FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6455, 318 aa 1>>>pF1KB6455 318 - 318 aa - 318 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.3914+/-0.000473; mu= 14.2645+/- 0.029 mean_var=55.3427+/-10.850, 0's: 0 Z-trim(107.7): 43 B-trim: 75 in 1/50 Lambda= 0.172403 statistics sampled from 15774 (15810) to 15774 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.542), E-opt: 0.2 (0.185), width: 16 Scan time: 6.830 The best scores are: opt bits E(85289) NP_002755 (OMIM: 300661,301835,311070,311850) ribo ( 318) 2070 523.5 2.3e-148 NP_002756 (OMIM: 311860) ribose-phosphate pyrophos ( 318) 1990 503.6 2.2e-142 NP_001034180 (OMIM: 311860) ribose-phosphate pyrop ( 321) 1974 499.6 3.5e-141 NP_787082 (OMIM: 611566) ribose-phosphate pyrophos ( 318) 1953 494.4 1.3e-139 NP_001191331 (OMIM: 300661,301835,311070,311850) r ( 114) 738 192.1 4.7e-49 NP_001230869 (OMIM: 603762) phosphoribosyl pyropho ( 320) 604 158.8 1.3e-38 XP_005256786 (OMIM: 603762) PREDICTED: phosphoribo ( 283) 366 99.6 7.8e-21 XP_016880364 (OMIM: 603762) PREDICTED: phosphoribo ( 283) 366 99.6 7.8e-21 NP_001230871 (OMIM: 603762) phosphoribosyl pyropho ( 283) 366 99.6 7.8e-21 XP_016880362 (OMIM: 603762) PREDICTED: phosphoribo ( 283) 366 99.6 7.8e-21 XP_016880365 (OMIM: 603762) PREDICTED: phosphoribo ( 283) 366 99.6 7.8e-21 XP_016880361 (OMIM: 603762) PREDICTED: phosphoribo ( 283) 366 99.6 7.8e-21 XP_016880363 (OMIM: 603762) PREDICTED: phosphoribo ( 283) 366 99.6 7.8e-21 XP_016880360 (OMIM: 603762) PREDICTED: phosphoribo ( 283) 366 99.6 7.8e-21 NP_001230870 (OMIM: 603762) phosphoribosyl pyropho ( 283) 366 99.6 7.8e-21 XP_016880358 (OMIM: 603762) PREDICTED: phosphoribo ( 324) 366 99.7 8.8e-21 XP_016880357 (OMIM: 603762) PREDICTED: phosphoribo ( 324) 366 99.7 8.8e-21 XP_016880359 (OMIM: 603762) PREDICTED: phosphoribo ( 324) 366 99.7 8.8e-21 NP_001230865 (OMIM: 603762) phosphoribosyl pyropho ( 329) 366 99.7 9e-21 XP_016880354 (OMIM: 603762) PREDICTED: phosphoribo ( 369) 366 99.7 1e-20 XP_016880356 (OMIM: 603762) PREDICTED: phosphoribo ( 369) 366 99.7 1e-20 XP_005256783 (OMIM: 603762) PREDICTED: phosphoribo ( 369) 366 99.7 1e-20 XP_016880355 (OMIM: 603762) PREDICTED: phosphoribo ( 369) 366 99.7 1e-20 NP_002758 (OMIM: 603762) phosphoribosyl pyrophosph ( 369) 366 99.7 1e-20 XP_005256782 (OMIM: 603762) PREDICTED: phosphoribo ( 369) 366 99.7 1e-20 XP_016880353 (OMIM: 603762) PREDICTED: phosphoribo ( 423) 366 99.7 1.1e-20 NP_001317432 (OMIM: 601249) phosphoribosyl pyropho ( 282) 347 94.9 2.1e-19 NP_002757 (OMIM: 601249) phosphoribosyl pyrophosph ( 385) 347 94.9 2.7e-19 >>NP_002755 (OMIM: 300661,301835,311070,311850) ribose-p (318 aa) initn: 2070 init1: 2070 opt: 2070 Z-score: 2784.7 bits: 523.5 E(85289): 2.3e-148 Smith-Waterman score: 2070; 100.0% identity (100.0% similar) in 318 aa overlap (1-318:1-318) 10 20 30 40 50 60 pF1KB6 MPNIKIFSGSSHQDLSQKIADRLGLELGKVVTKKFSNQETCVEIGESVRGEDVYIVQSGC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MPNIKIFSGSSHQDLSQKIADRLGLELGKVVTKKFSNQETCVEIGESVRGEDVYIVQSGC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 GEINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPISAKLVANMLSVAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 GEINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPISAKLVANMLSVAG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 ADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIRENISEWRNCTIVSPDAGGAKRVTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 ADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIRENISEWRNCTIVSPDAGGAKRVTS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 IADRLNVDFALIHKERKKANEVDRMVLVGDVKDRVAILVDDMADTCGTICHAADKLLSAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 IADRLNVDFALIHKERKKANEVDRMVLVGDVKDRVAILVDDMADTCGTICHAADKLLSAG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 ATRVYAILTHGIFSGPAISRINNACFEAVVVTNTIPQEDKMKHCSKIQVIDISMILAEAI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 ATRVYAILTHGIFSGPAISRINNACFEAVVVTNTIPQEDKMKHCSKIQVIDISMILAEAI 250 260 270 280 290 300 310 pF1KB6 RRTHNGESVSYLFSHVPL :::::::::::::::::: NP_002 RRTHNGESVSYLFSHVPL 310 >>NP_002756 (OMIM: 311860) ribose-phosphate pyrophosphok (318 aa) initn: 1990 init1: 1990 opt: 1990 Z-score: 2677.2 bits: 503.6 E(85289): 2.2e-142 Smith-Waterman score: 1990; 95.3% identity (98.7% similar) in 318 aa overlap (1-318:1-318) 10 20 30 40 50 60 pF1KB6 MPNIKIFSGSSHQDLSQKIADRLGLELGKVVTKKFSNQETCVEIGESVRGEDVYIVQSGC :::: .:::::::::::..::::::::::::::::::::: ::::::::::::::.:::: NP_002 MPNIVLFSGSSHQDLSQRVADRLGLELGKVVTKKFSNQETSVEIGESVRGEDVYIIQSGC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 GEINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPISAKLVANMLSVAG :::::::::::::::::::::.:::::::::::::::::::::::::::::::::::::: NP_002 GEINDNLMELLIMINACKIASSSRVTAVIPCFPYARQDKKDKSRAPISAKLVANMLSVAG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 ADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIRENISEWRNCTIVSPDAGGAKRVTS ::::::::::::::::::::::::::::::::.::::::.::.:: :::::::::::::: NP_002 ADHIITMDLHASQIQGFFDIPVDNLYAEPAVLQWIRENIAEWKNCIIVSPDAGGAKRVTS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 IADRLNVDFALIHKERKKANEVDRMVLVGDVKDRVAILVDDMADTCGTICHAADKLLSAG :::::::.:::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 IADRLNVEFALIHKERKKANEVDRMVLVGDVKDRVAILVDDMADTCGTICHAADKLLSAG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 ATRVYAILTHGIFSGPAISRINNACFEAVVVTNTIPQEDKMKHCSKIQVIDISMILAEAI ::.::::::::::::::::::::: :::::::::::::::::::.::::::::::::::: NP_002 ATKVYAILTHGIFSGPAISRINNAAFEAVVVTNTIPQEDKMKHCTKIQVIDISMILAEAI 250 260 270 280 290 300 310 pF1KB6 RRTHNGESVSYLFSHVPL :::::::::::::::::: NP_002 RRTHNGESVSYLFSHVPL 310 >>NP_001034180 (OMIM: 311860) ribose-phosphate pyrophosp (321 aa) initn: 1375 init1: 1375 opt: 1974 Z-score: 2655.6 bits: 499.6 E(85289): 3.5e-141 Smith-Waterman score: 1974; 94.4% identity (97.8% similar) in 321 aa overlap (1-318:1-321) 10 20 30 40 50 60 pF1KB6 MPNIKIFSGSSHQDLSQKIADRLGLELGKVVTKKFSNQETCVEIGESVRGEDVYIVQSGC :::: .:::::::::::..::::::::::::::::::::: ::::::::::::::.:::: NP_001 MPNIVLFSGSSHQDLSQRVADRLGLELGKVVTKKFSNQETSVEIGESVRGEDVYIIQSGC 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 GEINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDK---SRAPISAKLVANMLS :::::::::::::::::::::.:::::::::::::::::::: ::::::::::::::: NP_001 GEINDNLMELLIMINACKIASSSRVTAVIPCFPYARQDKKDKVGESRAPISAKLVANMLS 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 VAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIRENISEWRNCTIVSPDAGGAKR :::::::::::::::::::::::::::::::::::.::::::.::.:: ::::::::::: NP_001 VAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLQWIRENIAEWKNCIIVSPDAGGAKR 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB6 VTSIADRLNVDFALIHKERKKANEVDRMVLVGDVKDRVAILVDDMADTCGTICHAADKLL ::::::::::.::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VTSIADRLNVEFALIHKERKKANEVDRMVLVGDVKDRVAILVDDMADTCGTICHAADKLL 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB6 SAGATRVYAILTHGIFSGPAISRINNACFEAVVVTNTIPQEDKMKHCSKIQVIDISMILA :::::.::::::::::::::::::::: :::::::::::::::::::.:::::::::::: NP_001 SAGATKVYAILTHGIFSGPAISRINNAAFEAVVVTNTIPQEDKMKHCTKIQVIDISMILA 250 260 270 280 290 300 300 310 pF1KB6 EAIRRTHNGESVSYLFSHVPL ::::::::::::::::::::: NP_001 EAIRRTHNGESVSYLFSHVPL 310 320 >>NP_787082 (OMIM: 611566) ribose-phosphate pyrophosphok (318 aa) initn: 1953 init1: 1953 opt: 1953 Z-score: 2627.5 bits: 494.4 E(85289): 1.3e-139 Smith-Waterman score: 1953; 94.3% identity (98.1% similar) in 318 aa overlap (1-318:1-318) 10 20 30 40 50 60 pF1KB6 MPNIKIFSGSSHQDLSQKIADRLGLELGKVVTKKFSNQETCVEIGESVRGEDVYIVQSGC :::::::::::::::::::::::::::::::::::::::::::: ::::::::::::::: NP_787 MPNIKIFSGSSHQDLSQKIADRLGLELGKVVTKKFSNQETCVEIDESVRGEDVYIVQSGC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 GEINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRAPISAKLVANMLSVAG :::::.::::::::::::::::::::::::::::::::::::::.::::::::::::.:: NP_787 GEINDSLMELLIMINACKIASASRVTAVIPCFPYARQDKKDKSRSPISAKLVANMLSIAG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 ADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIRENISEWRNCTIVSPDAGGAKRVTS :::::::::::::::::::::::::::::.::::::::: ::.:: :::::::::::::: NP_787 ADHIITMDLHASQIQGFFDIPVDNLYAEPTVLKWIRENIPEWKNCIIVSPDAGGAKRVTS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 IADRLNVDFALIHKERKKANEVDRMVLVGDVKDRVAILVDDMADTCGTICHAADKLLSAG :::.::::::::::::::::::: .::::::.:::::::::::::: ::: ::::::::: NP_787 IADQLNVDFALIHKERKKANEVDCIVLVGDVNDRVAILVDDMADTCVTICLAADKLLSAG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 ATRVYAILTHGIFSGPAISRINNACFEAVVVTNTIPQEDKMKHCSKIQVIDISMILAEAI ::::::::::::::::::::::.::::::::::::::..::::::::.:::::::::::: NP_787 ATRVYAILTHGIFSGPAISRINTACFEAVVVTNTIPQDEKMKHCSKIRVIDISMILAEAI 250 260 270 280 290 300 310 pF1KB6 RRTHNGESVSYLFSHVPL :::::::::::::::::: NP_787 RRTHNGESVSYLFSHVPL 310 >>NP_001191331 (OMIM: 300661,301835,311070,311850) ribos (114 aa) initn: 738 init1: 738 opt: 738 Z-score: 1001.7 bits: 192.1 E(85289): 4.7e-49 Smith-Waterman score: 738; 100.0% identity (100.0% similar) in 114 aa overlap (205-318:1-114) 180 190 200 210 220 230 pF1KB6 AKRVTSIADRLNVDFALIHKERKKANEVDRMVLVGDVKDRVAILVDDMADTCGTICHAAD :::::::::::::::::::::::::::::: NP_001 MVLVGDVKDRVAILVDDMADTCGTICHAAD 10 20 30 240 250 260 270 280 290 pF1KB6 KLLSAGATRVYAILTHGIFSGPAISRINNACFEAVVVTNTIPQEDKMKHCSKIQVIDISM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KLLSAGATRVYAILTHGIFSGPAISRINNACFEAVVVTNTIPQEDKMKHCSKIQVIDISM 40 50 60 70 80 90 300 310 pF1KB6 ILAEAIRRTHNGESVSYLFSHVPL :::::::::::::::::::::::: NP_001 ILAEAIRRTHNGESVSYLFSHVPL 100 110 >>NP_001230869 (OMIM: 603762) phosphoribosyl pyrophospha (320 aa) initn: 837 init1: 320 opt: 604 Z-score: 814.1 bits: 158.8 E(85289): 1.3e-38 Smith-Waterman score: 752; 46.0% identity (70.4% similar) in 311 aa overlap (8-318:27-318) 10 20 30 40 pF1KB6 MPNIKIFSGSSHQDLSQKIADRLGLELGKVVTKKFSNQETC :.:: ..::.:::.:::.:.::: . . :.:: NP_001 MFCVTPPELETKMNITKGGLVLFSANSNSSCMELSKKIAERLGVEMGKVQVYQEPNRETR 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB6 VEIGESVRGEDVYIVQSGCGEINDNLMELLIMINACKIASASRVTAVIPCFPYARQDKKD :.: :::::.::.:.:. ..: ..::::::. ::: . :. . .::: :::..: : NP_001 VQIQESVRGKDVFIIQTVSKDVNTTIMELLIMVYACKTSCAKSIIGVIPYFPYSKQCKMR 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB6 KSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIRENISE : :. : .::.:.:. :: :.:::::: ..:::::.:::::: : : .:..:.:.: . NP_001 K-RGSIVSKLLASMMCKAGLTHLITMDLHQKEIQGFFNIPVDNLRASPFLLQYIQEEIPD 130 140 150 160 170 170 180 190 200 210 220 pF1KB6 WRNCTIVSPDAGGAKRVTSIADRLNVDFALIHKERKKANEVDRMVLVGDVKDRVAILVDD .:: .::. . ..:::. :.:.:: . .:.:: : . : : : :: : . NP_001 YRNAVIVAKSPASAKRAQSFAERLRLGIAVIHGEAQDA-ESD---LV-DGRHS-----PP 180 190 200 210 220 230 240 250 260 270 280 pF1KB6 MADTCGTICHAADKLLSAGATRVYAILTHGIFSGPAISRINNACFEAVVVTNTIPQEDKM :. . ..: : . .. . : . : .: :: .::::::::.: . NP_001 MVRSVAAI-HPSLEIPMLIPKEKPPITVVGDVGG----RIAII---VVVVTNTIPHEVQK 230 240 250 260 270 280 290 300 310 pF1KB6 KHCSKIQVIDISMILAEAIRRTHNGESVSYLFSHVPL .: ::...::::::.::::: :::::.:::: .. : NP_001 LQCPKIKTVDISMILSEAIRRIHNGESMSYLFRNIGLDD 290 300 310 320 >>XP_005256786 (OMIM: 603762) PREDICTED: phosphoribosyl (283 aa) initn: 762 init1: 359 opt: 366 Z-score: 495.0 bits: 99.6 E(85289): 7.8e-21 Smith-Waterman score: 711; 44.0% identity (68.4% similar) in 282 aa overlap (68-318:1-281) 40 50 60 70 80 90 pF1KB6 QETCVEIGESVRGEDVYIVQSGCGEINDNLMELLIMINACKIASASRVTAVIPCFPYARQ ::::::. ::: . :. . .::: :::..: XP_005 MELLIMVYACKTSCAKSIIGVIPYFPYSKQ 10 20 30 100 110 120 130 140 150 pF1KB6 DKKDKSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIRE : : :. : .::.:.:. :: :.:::::: ..:::::.:::::: : : .:..:.: XP_005 CKMRK-RGSIVSKLLASMMCKAGLTHLITMDLHQKEIQGFFNIPVDNLRASPFLLQYIQE 40 50 60 70 80 160 170 180 190 200 pF1KB6 NISEWRNCTIVSPDAGGAKRVTSIADRLNVDFALIHKERKKAN----------------- .: ..:: .::. . ..:::. :.:.:: . .:.:: : . :. XP_005 EIPDYRNAVIVAKSPASAKRAQSFAERLRLGIAVIHGEAQDAESDLVDGRHSPPMVRSVA 90 100 110 120 130 140 210 220 230 240 pF1KB6 ------EVDRMV--------LVGDVKDRVAILVDDMADTCGTICHAADKLLSAGATRVYA :. .. .:::: :.::.:::. : .. ::. : :: .... XP_005 AIHPSLEIPMLIPKEKPPITVVGDVGGRIAIIVDDIIDDVDSFLAAAETLKERGAYKIFV 150 160 170 180 190 200 250 260 270 280 290 300 pF1KB6 ILTHGIFSGPAISRINNACFEAVVVTNTIPQEDKMKHCSKIQVIDISMILAEAIRRTHNG . :::..:. : ::... .. ::::::::.: . .: ::...::::::.::::: ::: XP_005 MATHGLLSSDAPRRIEESAIDEVVVTNTIPHEVQKLQCPKIKTVDISMILSEAIRRIHNG 210 220 230 240 250 260 310 pF1KB6 ESVSYLFSHVPL ::.:::: .. : XP_005 ESMSYLFRNIGLDD 270 280 >>XP_016880364 (OMIM: 603762) PREDICTED: phosphoribosyl (283 aa) initn: 762 init1: 359 opt: 366 Z-score: 495.0 bits: 99.6 E(85289): 7.8e-21 Smith-Waterman score: 711; 44.0% identity (68.4% similar) in 282 aa overlap (68-318:1-281) 40 50 60 70 80 90 pF1KB6 QETCVEIGESVRGEDVYIVQSGCGEINDNLMELLIMINACKIASASRVTAVIPCFPYARQ ::::::. ::: . :. . .::: :::..: XP_016 MELLIMVYACKTSCAKSIIGVIPYFPYSKQ 10 20 30 100 110 120 130 140 150 pF1KB6 DKKDKSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIRE : : :. : .::.:.:. :: :.:::::: ..:::::.:::::: : : .:..:.: XP_016 CKMRK-RGSIVSKLLASMMCKAGLTHLITMDLHQKEIQGFFNIPVDNLRASPFLLQYIQE 40 50 60 70 80 160 170 180 190 200 pF1KB6 NISEWRNCTIVSPDAGGAKRVTSIADRLNVDFALIHKERKKAN----------------- .: ..:: .::. . ..:::. :.:.:: . .:.:: : . :. XP_016 EIPDYRNAVIVAKSPASAKRAQSFAERLRLGIAVIHGEAQDAESDLVDGRHSPPMVRSVA 90 100 110 120 130 140 210 220 230 240 pF1KB6 ------EVDRMV--------LVGDVKDRVAILVDDMADTCGTICHAADKLLSAGATRVYA :. .. .:::: :.::.:::. : .. ::. : :: .... XP_016 AIHPSLEIPMLIPKEKPPITVVGDVGGRIAIIVDDIIDDVDSFLAAAETLKERGAYKIFV 150 160 170 180 190 200 250 260 270 280 290 300 pF1KB6 ILTHGIFSGPAISRINNACFEAVVVTNTIPQEDKMKHCSKIQVIDISMILAEAIRRTHNG . :::..:. : ::... .. ::::::::.: . .: ::...::::::.::::: ::: XP_016 MATHGLLSSDAPRRIEESAIDEVVVTNTIPHEVQKLQCPKIKTVDISMILSEAIRRIHNG 210 220 230 240 250 260 310 pF1KB6 ESVSYLFSHVPL ::.:::: .. : XP_016 ESMSYLFRNIGLDD 270 280 >>NP_001230871 (OMIM: 603762) phosphoribosyl pyrophospha (283 aa) initn: 762 init1: 359 opt: 366 Z-score: 495.0 bits: 99.6 E(85289): 7.8e-21 Smith-Waterman score: 711; 44.0% identity (68.4% similar) in 282 aa overlap (68-318:1-281) 40 50 60 70 80 90 pF1KB6 QETCVEIGESVRGEDVYIVQSGCGEINDNLMELLIMINACKIASASRVTAVIPCFPYARQ ::::::. ::: . :. . .::: :::..: NP_001 MELLIMVYACKTSCAKSIIGVIPYFPYSKQ 10 20 30 100 110 120 130 140 150 pF1KB6 DKKDKSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIRE : : :. : .::.:.:. :: :.:::::: ..:::::.:::::: : : .:..:.: NP_001 CKMRK-RGSIVSKLLASMMCKAGLTHLITMDLHQKEIQGFFNIPVDNLRASPFLLQYIQE 40 50 60 70 80 160 170 180 190 200 pF1KB6 NISEWRNCTIVSPDAGGAKRVTSIADRLNVDFALIHKERKKAN----------------- .: ..:: .::. . ..:::. :.:.:: . .:.:: : . :. NP_001 EIPDYRNAVIVAKSPASAKRAQSFAERLRLGIAVIHGEAQDAESDLVDGRHSPPMVRSVA 90 100 110 120 130 140 210 220 230 240 pF1KB6 ------EVDRMV--------LVGDVKDRVAILVDDMADTCGTICHAADKLLSAGATRVYA :. .. .:::: :.::.:::. : .. ::. : :: .... NP_001 AIHPSLEIPMLIPKEKPPITVVGDVGGRIAIIVDDIIDDVDSFLAAAETLKERGAYKIFV 150 160 170 180 190 200 250 260 270 280 290 300 pF1KB6 ILTHGIFSGPAISRINNACFEAVVVTNTIPQEDKMKHCSKIQVIDISMILAEAIRRTHNG . :::..:. : ::... .. ::::::::.: . .: ::...::::::.::::: ::: NP_001 MATHGLLSSDAPRRIEESAIDEVVVTNTIPHEVQKLQCPKIKTVDISMILSEAIRRIHNG 210 220 230 240 250 260 310 pF1KB6 ESVSYLFSHVPL ::.:::: .. : NP_001 ESMSYLFRNIGLDD 270 280 >>XP_016880362 (OMIM: 603762) PREDICTED: phosphoribosyl (283 aa) initn: 762 init1: 359 opt: 366 Z-score: 495.0 bits: 99.6 E(85289): 7.8e-21 Smith-Waterman score: 711; 44.0% identity (68.4% similar) in 282 aa overlap (68-318:1-281) 40 50 60 70 80 90 pF1KB6 QETCVEIGESVRGEDVYIVQSGCGEINDNLMELLIMINACKIASASRVTAVIPCFPYARQ ::::::. ::: . :. . .::: :::..: XP_016 MELLIMVYACKTSCAKSIIGVIPYFPYSKQ 10 20 30 100 110 120 130 140 150 pF1KB6 DKKDKSRAPISAKLVANMLSVAGADHIITMDLHASQIQGFFDIPVDNLYAEPAVLKWIRE : : :. : .::.:.:. :: :.:::::: ..:::::.:::::: : : .:..:.: XP_016 CKMRK-RGSIVSKLLASMMCKAGLTHLITMDLHQKEIQGFFNIPVDNLRASPFLLQYIQE 40 50 60 70 80 160 170 180 190 200 pF1KB6 NISEWRNCTIVSPDAGGAKRVTSIADRLNVDFALIHKERKKAN----------------- .: ..:: .::. . ..:::. :.:.:: . .:.:: : . :. XP_016 EIPDYRNAVIVAKSPASAKRAQSFAERLRLGIAVIHGEAQDAESDLVDGRHSPPMVRSVA 90 100 110 120 130 140 210 220 230 240 pF1KB6 ------EVDRMV--------LVGDVKDRVAILVDDMADTCGTICHAADKLLSAGATRVYA :. .. .:::: :.::.:::. : .. ::. : :: .... XP_016 AIHPSLEIPMLIPKEKPPITVVGDVGGRIAIIVDDIIDDVDSFLAAAETLKERGAYKIFV 150 160 170 180 190 200 250 260 270 280 290 300 pF1KB6 ILTHGIFSGPAISRINNACFEAVVVTNTIPQEDKMKHCSKIQVIDISMILAEAIRRTHNG . :::..:. : ::... .. ::::::::.: . .: ::...::::::.::::: ::: XP_016 MATHGLLSSDAPRRIEESAIDEVVVTNTIPHEVQKLQCPKIKTVDISMILSEAIRRIHNG 210 220 230 240 250 260 310 pF1KB6 ESVSYLFSHVPL ::.:::: .. : XP_016 ESMSYLFRNIGLDD 270 280 318 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 23:02:03 2016 done: Fri Nov 4 23:02:04 2016 Total Scan time: 6.830 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]