FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6456, 351 aa
1>>>pF1KB6456 351 - 351 aa - 351 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.0862+/-0.000407; mu= 17.5390+/- 0.026
mean_var=61.6119+/-12.472, 0's: 0 Z-trim(109.8): 25 B-trim: 325 in 1/52
Lambda= 0.163396
statistics sampled from 17978 (17991) to 17978 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.576), E-opt: 0.2 (0.211), width: 16
Scan time: 7.050
The best scores are: opt bits E(85289)
NP_056528 (OMIM: 604712,612075,613077) ribonucleos ( 351) 2328 557.6 1.5e-158
NP_001165948 (OMIM: 604712,612075,613077) ribonucl ( 423) 2220 532.2 7.9e-151
NP_001165949 (OMIM: 604712,612075,613077) ribonucl ( 299) 1877 451.3 1.3e-126
NP_001025 (OMIM: 180390) ribonucleoside-diphosphat ( 389) 1861 447.5 2.2e-125
NP_001159403 (OMIM: 180390) ribonucleoside-diphosp ( 449) 1861 447.6 2.5e-125
>>NP_056528 (OMIM: 604712,612075,613077) ribonucleoside- (351 aa)
initn: 2328 init1: 2328 opt: 2328 Z-score: 2967.7 bits: 557.6 E(85289): 1.5e-158
Smith-Waterman score: 2328; 100.0% identity (100.0% similar) in 351 aa overlap (1-351:1-351)
10 20 30 40 50 60
pF1KB6 MGDPERPEAAGLDQDERSSSDTNESEIKSNEEPLLRKSSRRFVIFPIQYPDIWKMYKQAQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 MGDPERPEAAGLDQDERSSSDTNESEIKSNEEPLLRKSSRRFVIFPIQYPDIWKMYKQAQ
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 ASFWTAEEVDLSKDLPHWNKLKADEKYFISHILAFFAASDGIVNENLVERFSQEVQVPEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 ASFWTAEEVDLSKDLPHWNKLKADEKYFISHILAFFAASDGIVNENLVERFSQEVQVPEA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 RCFYGFQILIENVHSEMYSLLIDTYIRDPKKREFLFNAIETMPYVKKKADWALRWIADRK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 RCFYGFQILIENVHSEMYSLLIDTYIRDPKKREFLFNAIETMPYVKKKADWALRWIADRK
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 STFGERVVAFAAVEGVFFSGSFAAIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 STFGERVVAFAAVEGVFFSGSFAAIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 YLVNKPSEERVREIIVDAVKIEQEFLTEALPVGLIGMNCILMKQYIEFVADRLLVELGFS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 YLVNKPSEERVREIIVDAVKIEQEFLTEALPVGLIGMNCILMKQYIEFVADRLLVELGFS
250 260 270 280 290 300
310 320 330 340 350
pF1KB6 KVFQAENPFDFMENISLEGKTNFFEKRVSEYQRFAVMAETTDNVFTLDADF
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_056 KVFQAENPFDFMENISLEGKTNFFEKRVSEYQRFAVMAETTDNVFTLDADF
310 320 330 340 350
>>NP_001165948 (OMIM: 604712,612075,613077) ribonucleosi (423 aa)
initn: 2214 init1: 2214 opt: 2220 Z-score: 2828.9 bits: 532.2 E(85289): 7.9e-151
Smith-Waterman score: 2220; 97.1% identity (97.7% similar) in 349 aa overlap (3-351:81-423)
10 20 30
pF1KB6 MGDPERPEAAGLDQDERSSSDTNESEIKSNEE
: ::.:. ::::::::::::::::
NP_001 RGGRPRGGRRKELTLGLRPARCSAPGPAKDDAWRPQAG------RSSSDTNESEIKSNEE
60 70 80 90 100
40 50 60 70 80 90
pF1KB6 PLLRKSSRRFVIFPIQYPDIWKMYKQAQASFWTAEEVDLSKDLPHWNKLKADEKYFISHI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 PLLRKSSRRFVIFPIQYPDIWKMYKQAQASFWTAEEVDLSKDLPHWNKLKADEKYFISHI
110 120 130 140 150 160
100 110 120 130 140 150
pF1KB6 LAFFAASDGIVNENLVERFSQEVQVPEARCFYGFQILIENVHSEMYSLLIDTYIRDPKKR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LAFFAASDGIVNENLVERFSQEVQVPEARCFYGFQILIENVHSEMYSLLIDTYIRDPKKR
170 180 190 200 210 220
160 170 180 190 200 210
pF1KB6 EFLFNAIETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGVFFSGSFAAIFWLKKRG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 EFLFNAIETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGVFFSGSFAAIFWLKKRG
230 240 250 260 270 280
220 230 240 250 260 270
pF1KB6 LMPGLTFSNELISRDEGLHCDFACLMFQYLVNKPSEERVREIIVDAVKIEQEFLTEALPV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LMPGLTFSNELISRDEGLHCDFACLMFQYLVNKPSEERVREIIVDAVKIEQEFLTEALPV
290 300 310 320 330 340
280 290 300 310 320 330
pF1KB6 GLIGMNCILMKQYIEFVADRLLVELGFSKVFQAENPFDFMENISLEGKTNFFEKRVSEYQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 GLIGMNCILMKQYIEFVADRLLVELGFSKVFQAENPFDFMENISLEGKTNFFEKRVSEYQ
350 360 370 380 390 400
340 350
pF1KB6 RFAVMAETTDNVFTLDADF
:::::::::::::::::::
NP_001 RFAVMAETTDNVFTLDADF
410 420
>>NP_001165949 (OMIM: 604712,612075,613077) ribonucleosi (299 aa)
initn: 1876 init1: 1876 opt: 1877 Z-score: 2394.1 bits: 451.3 E(85289): 1.3e-126
Smith-Waterman score: 1877; 96.6% identity (98.3% similar) in 295 aa overlap (57-351:5-299)
30 40 50 60 70 80
pF1KB6 IKSNEEPLLRKSSRRFVIFPIQYPDIWKMYKQAQASFWTAEEVDLSKDLPHWNKLKADEK
.. .:. .:::::::::::::::::::
NP_001 MGDPERPEAAGLDQDEVDLSKDLPHWNKLKADEK
10 20 30
90 100 110 120 130 140
pF1KB6 YFISHILAFFAASDGIVNENLVERFSQEVQVPEARCFYGFQILIENVHSEMYSLLIDTYI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YFISHILAFFAASDGIVNENLVERFSQEVQVPEARCFYGFQILIENVHSEMYSLLIDTYI
40 50 60 70 80 90
150 160 170 180 190 200
pF1KB6 RDPKKREFLFNAIETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGVFFSGSFAAIF
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RDPKKREFLFNAIETMPYVKKKADWALRWIADRKSTFGERVVAFAAVEGVFFSGSFAAIF
100 110 120 130 140 150
210 220 230 240 250 260
pF1KB6 WLKKRGLMPGLTFSNELISRDEGLHCDFACLMFQYLVNKPSEERVREIIVDAVKIEQEFL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 WLKKRGLMPGLTFSNELISRDEGLHCDFACLMFQYLVNKPSEERVREIIVDAVKIEQEFL
160 170 180 190 200 210
270 280 290 300 310 320
pF1KB6 TEALPVGLIGMNCILMKQYIEFVADRLLVELGFSKVFQAENPFDFMENISLEGKTNFFEK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 TEALPVGLIGMNCILMKQYIEFVADRLLVELGFSKVFQAENPFDFMENISLEGKTNFFEK
220 230 240 250 260 270
330 340 350
pF1KB6 RVSEYQRFAVMAETTDNVFTLDADF
:::::::::::::::::::::::::
NP_001 RVSEYQRFAVMAETTDNVFTLDADF
280 290
>>NP_001025 (OMIM: 180390) ribonucleoside-diphosphate re (389 aa)
initn: 1861 init1: 1861 opt: 1861 Z-score: 2372.1 bits: 447.5 E(85289): 2.2e-125
Smith-Waterman score: 1861; 83.8% identity (96.3% similar) in 321 aa overlap (31-351:69-389)
10 20 30 40 50 60
pF1KB6 MGDPERPEAAGLDQDERSSSDTNESEIKSNEEPLLRKSSRRFVIFPIQYPDIWKMYKQAQ
.:::::.. ::::::::.: :::.:::.:.
NP_001 GTRVLASKTARRIFQEPTEPKTKAAAPGVEDEPLLRENPRRFVIFPIEYHDIWQMYKKAE
40 50 60 70 80 90
70 80 90 100 110 120
pF1KB6 ASFWTAEEVDLSKDLPHWNKLKADEKYFISHILAFFAASDGIVNENLVERFSQEVQVPEA
::::::::::::::. ::..:: .:.:::::.::::::::::::::::::::::::. ::
NP_001 ASFWTAEEVDLSKDIQHWESLKPEERYFISHVLAFFAASDGIVNENLVERFSQEVQITEA
100 110 120 130 140 150
130 140 150 160 170 180
pF1KB6 RCFYGFQILIENVHSEMYSLLIDTYIRDPKKREFLFNAIETMPYVKKKADWALRWIADRK
:::::::: .::.:::::::::::::.:::.:::::::::::: ::::::::::::.:..
NP_001 RCFYGFQIAMENIHSEMYSLLIDTYIKDPKEREFLFNAIETMPCVKKKADWALRWIGDKE
160 170 180 190 200 210
190 200 210 220 230 240
pF1KB6 STFGERVVAFAAVEGVFFSGSFAAIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFQ
.:.::::::::::::.:::::::.:::::::::::::::::::::::::::::::::::.
NP_001 ATYGERVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFK
220 230 240 250 260 270
250 260 270 280 290 300
pF1KB6 YLVNKPSEERVREIIVDAVKIEQEFLTEALPVGLIGMNCILMKQYIEFVADRLLVELGFS
.::.:::::::::::..::.:::::::::::: :::::: :::::::::::::..:::::
NP_001 HLVHKPSEERVREIIINAVRIEQEFLTEALPVKLIGMNCTLMKQYIEFVADRLMLELGFS
280 290 300 310 320 330
310 320 330 340 350
pF1KB6 KVFQAENPFDFMENISLEGKTNFFEKRVSEYQRFAVMAETTDNVFTLDADF
:::..:::::::::::::::::::::::.::::..::. :.: :::::::
NP_001 KVFRVENPFDFMENISLEGKTNFFEKRVGEYQRMGVMSSPTENSFTLDADF
340 350 360 370 380
>>NP_001159403 (OMIM: 180390) ribonucleoside-diphosphate (449 aa)
initn: 1861 init1: 1861 opt: 1861 Z-score: 2371.1 bits: 447.6 E(85289): 2.5e-125
Smith-Waterman score: 1861; 83.8% identity (96.3% similar) in 321 aa overlap (31-351:129-449)
10 20 30 40 50 60
pF1KB6 MGDPERPEAAGLDQDERSSSDTNESEIKSNEEPLLRKSSRRFVIFPIQYPDIWKMYKQAQ
.:::::.. ::::::::.: :::.:::.:.
NP_001 GTRVLASKTARRIFQEPTEPKTKAAAPGVEDEPLLRENPRRFVIFPIEYHDIWQMYKKAE
100 110 120 130 140 150
70 80 90 100 110 120
pF1KB6 ASFWTAEEVDLSKDLPHWNKLKADEKYFISHILAFFAASDGIVNENLVERFSQEVQVPEA
::::::::::::::. ::..:: .:.:::::.::::::::::::::::::::::::. ::
NP_001 ASFWTAEEVDLSKDIQHWESLKPEERYFISHVLAFFAASDGIVNENLVERFSQEVQITEA
160 170 180 190 200 210
130 140 150 160 170 180
pF1KB6 RCFYGFQILIENVHSEMYSLLIDTYIRDPKKREFLFNAIETMPYVKKKADWALRWIADRK
:::::::: .::.:::::::::::::.:::.:::::::::::: ::::::::::::.:..
NP_001 RCFYGFQIAMENIHSEMYSLLIDTYIKDPKEREFLFNAIETMPCVKKKADWALRWIGDKE
220 230 240 250 260 270
190 200 210 220 230 240
pF1KB6 STFGERVVAFAAVEGVFFSGSFAAIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFQ
.:.::::::::::::.:::::::.:::::::::::::::::::::::::::::::::::.
NP_001 ATYGERVVAFAAVEGIFFSGSFASIFWLKKRGLMPGLTFSNELISRDEGLHCDFACLMFK
280 290 300 310 320 330
250 260 270 280 290 300
pF1KB6 YLVNKPSEERVREIIVDAVKIEQEFLTEALPVGLIGMNCILMKQYIEFVADRLLVELGFS
.::.:::::::::::..::.:::::::::::: :::::: :::::::::::::..:::::
NP_001 HLVHKPSEERVREIIINAVRIEQEFLTEALPVKLIGMNCTLMKQYIEFVADRLMLELGFS
340 350 360 370 380 390
310 320 330 340 350
pF1KB6 KVFQAENPFDFMENISLEGKTNFFEKRVSEYQRFAVMAETTDNVFTLDADF
:::..:::::::::::::::::::::::.::::..::. :.: :::::::
NP_001 KVFRVENPFDFMENISLEGKTNFFEKRVGEYQRMGVMSSPTENSFTLDADF
400 410 420 430 440
351 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 16:46:16 2016 done: Sat Nov 5 16:46:17 2016
Total Scan time: 7.050 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]