FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6458, 351 aa 1>>>pF1KB6458 351 - 351 aa - 351 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.4281+/-0.000332; mu= 6.1311+/- 0.021 mean_var=123.6986+/-25.954, 0's: 0 Z-trim(118.9): 13 B-trim: 2292 in 2/49 Lambda= 0.115317 statistics sampled from 32386 (32410) to 32386 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.749), E-opt: 0.2 (0.38), width: 16 Scan time: 9.040 The best scores are: opt bits E(85289) NP_054829 (OMIM: 602636) nuclear inhibitor of prot ( 351) 2378 406.5 4.5e-113 NP_612568 (OMIM: 602636) nuclear inhibitor of prot ( 209) 1407 244.8 1.2e-64 NP_002704 (OMIM: 602636) nuclear inhibitor of prot ( 127) 872 155.7 5e-38 XP_016857083 (OMIM: 602636) PREDICTED: nuclear inh ( 127) 872 155.7 5e-38 >>NP_054829 (OMIM: 602636) nuclear inhibitor of protein (351 aa) initn: 2378 init1: 2378 opt: 2378 Z-score: 2151.0 bits: 406.5 E(85289): 4.5e-113 Smith-Waterman score: 2378; 100.0% identity (100.0% similar) in 351 aa overlap (1-351:1-351) 10 20 30 40 50 60 pF1KB6 MAAAANSGSSLPLFDCPTWAGKPPPGLHLDVVKGDKLIEKLIIDEKKYYLFGRNPDLCDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 MAAAANSGSSLPLFDCPTWAGKPPPGLHLDVVKGDKLIEKLIIDEKKYYLFGRNPDLCDF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 TIDHQSCSRVHAALVYHKHLKRVFLIDLNSTHGTFLGHIRLEPHKPQQIPIDSTVSFGAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 TIDHQSCSRVHAALVYHKHLKRVFLIDLNSTHGTFLGHIRLEPHKPQQIPIDSTVSFGAS 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 TRAYTLREKPQTLPSAVKGDEKMGGEDDELKGLLGLPEEETELDNLTEFNTAHNKRISTL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 TRAYTLREKPQTLPSAVKGDEKMGGEDDELKGLLGLPEEETELDNLTEFNTAHNKRISTL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 TIEEGNLDIQRPKRKRKNSRVTFSEDDEIINPEDVDPSVGRFRNMVQTAVVPVKKKRVEG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 TIEEGNLDIQRPKRKRKNSRVTFSEDDEIINPEDVDPSVGRFRNMVQTAVVPVKKKRVEG 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 PGSLGLEESGSRRMQNFAFSGGLYGGLPPTHSEAGSQPHGIHGTALIGGLPMPYPNLAPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 PGSLGLEESGSRRMQNFAFSGGLYGGLPPTHSEAGSQPHGIHGTALIGGLPMPYPNLAPD 250 260 270 280 290 300 310 320 330 340 350 pF1KB6 VDLTPVVPSAVNMNPAPNPAVYNPEAVNEPKKKKYAKEAWPGKKPTPSLLI ::::::::::::::::::::::::::::::::::::::::::::::::::: NP_054 VDLTPVVPSAVNMNPAPNPAVYNPEAVNEPKKKKYAKEAWPGKKPTPSLLI 310 320 330 340 350 >>NP_612568 (OMIM: 602636) nuclear inhibitor of protein (209 aa) initn: 1407 init1: 1407 opt: 1407 Z-score: 1281.4 bits: 244.8 E(85289): 1.2e-64 Smith-Waterman score: 1407; 100.0% identity (100.0% similar) in 209 aa overlap (143-351:1-209) 120 130 140 150 160 170 pF1KB6 STVSFGASTRAYTLREKPQTLPSAVKGDEKMGGEDDELKGLLGLPEEETELDNLTEFNTA :::::::::::::::::::::::::::::: NP_612 MGGEDDELKGLLGLPEEETELDNLTEFNTA 10 20 30 180 190 200 210 220 230 pF1KB6 HNKRISTLTIEEGNLDIQRPKRKRKNSRVTFSEDDEIINPEDVDPSVGRFRNMVQTAVVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_612 HNKRISTLTIEEGNLDIQRPKRKRKNSRVTFSEDDEIINPEDVDPSVGRFRNMVQTAVVP 40 50 60 70 80 90 240 250 260 270 280 290 pF1KB6 VKKKRVEGPGSLGLEESGSRRMQNFAFSGGLYGGLPPTHSEAGSQPHGIHGTALIGGLPM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_612 VKKKRVEGPGSLGLEESGSRRMQNFAFSGGLYGGLPPTHSEAGSQPHGIHGTALIGGLPM 100 110 120 130 140 150 300 310 320 330 340 350 pF1KB6 PYPNLAPDVDLTPVVPSAVNMNPAPNPAVYNPEAVNEPKKKKYAKEAWPGKKPTPSLLI ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_612 PYPNLAPDVDLTPVVPSAVNMNPAPNPAVYNPEAVNEPKKKKYAKEAWPGKKPTPSLLI 160 170 180 190 200 >>NP_002704 (OMIM: 602636) nuclear inhibitor of protein (127 aa) initn: 872 init1: 872 opt: 872 Z-score: 803.7 bits: 155.7 E(85289): 5e-38 Smith-Waterman score: 872; 100.0% identity (100.0% similar) in 127 aa overlap (225-351:1-127) 200 210 220 230 240 250 pF1KB6 KRKNSRVTFSEDDEIINPEDVDPSVGRFRNMVQTAVVPVKKKRVEGPGSLGLEESGSRRM :::::::::::::::::::::::::::::: NP_002 MVQTAVVPVKKKRVEGPGSLGLEESGSRRM 10 20 30 260 270 280 290 300 310 pF1KB6 QNFAFSGGLYGGLPPTHSEAGSQPHGIHGTALIGGLPMPYPNLAPDVDLTPVVPSAVNMN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 QNFAFSGGLYGGLPPTHSEAGSQPHGIHGTALIGGLPMPYPNLAPDVDLTPVVPSAVNMN 40 50 60 70 80 90 320 330 340 350 pF1KB6 PAPNPAVYNPEAVNEPKKKKYAKEAWPGKKPTPSLLI ::::::::::::::::::::::::::::::::::::: NP_002 PAPNPAVYNPEAVNEPKKKKYAKEAWPGKKPTPSLLI 100 110 120 >>XP_016857083 (OMIM: 602636) PREDICTED: nuclear inhibit (127 aa) initn: 872 init1: 872 opt: 872 Z-score: 803.7 bits: 155.7 E(85289): 5e-38 Smith-Waterman score: 872; 100.0% identity (100.0% similar) in 127 aa overlap (225-351:1-127) 200 210 220 230 240 250 pF1KB6 KRKNSRVTFSEDDEIINPEDVDPSVGRFRNMVQTAVVPVKKKRVEGPGSLGLEESGSRRM :::::::::::::::::::::::::::::: XP_016 MVQTAVVPVKKKRVEGPGSLGLEESGSRRM 10 20 30 260 270 280 290 300 310 pF1KB6 QNFAFSGGLYGGLPPTHSEAGSQPHGIHGTALIGGLPMPYPNLAPDVDLTPVVPSAVNMN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QNFAFSGGLYGGLPPTHSEAGSQPHGIHGTALIGGLPMPYPNLAPDVDLTPVVPSAVNMN 40 50 60 70 80 90 320 330 340 350 pF1KB6 PAPNPAVYNPEAVNEPKKKKYAKEAWPGKKPTPSLLI ::::::::::::::::::::::::::::::::::::: XP_016 PAPNPAVYNPEAVNEPKKKKYAKEAWPGKKPTPSLLI 100 110 120 351 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 23:04:08 2016 done: Fri Nov 4 23:04:09 2016 Total Scan time: 9.040 Total Display time: -0.020 Function used was FASTA [36.3.4 Apr, 2011]