FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6460, 351 aa 1>>>pF1KB6460 351 - 351 aa - 351 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 10.9302+/-0.000658; mu= -12.9211+/- 0.038 mean_var=659.0814+/-153.519, 0's: 0 Z-trim(113.6): 1849 B-trim: 0 in 0/54 Lambda= 0.049958 statistics sampled from 20584 (23046) to 20584 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.616), E-opt: 0.2 (0.27), width: 16 Scan time: 6.800 The best scores are: opt bits E(85289) NP_002721 (OMIM: 601639,615830) cAMP-dependent pro ( 351) 2349 185.2 1.8e-46 NP_997401 (OMIM: 601639,615830) cAMP-dependent pro ( 343) 2262 179.0 1.4e-44 NP_001291278 (OMIM: 601639,615830) cAMP-dependent ( 427) 2258 178.8 1.9e-44 NP_002722 (OMIM: 176892) cAMP-dependent protein ki ( 351) 2186 173.5 6.2e-43 XP_006710821 (OMIM: 176892) PREDICTED: cAMP-depend ( 354) 2119 168.7 1.8e-41 NP_001229788 (OMIM: 176892) cAMP-dependent protein ( 355) 2119 168.7 1.8e-41 XP_005271075 (OMIM: 176892) PREDICTED: cAMP-depend ( 346) 2117 168.5 1.9e-41 XP_005271074 (OMIM: 176892) PREDICTED: cAMP-depend ( 347) 2117 168.5 1.9e-41 XP_005271076 (OMIM: 176892) PREDICTED: cAMP-depend ( 338) 2115 168.4 2.1e-41 XP_005271072 (OMIM: 176892) PREDICTED: cAMP-depend ( 350) 2112 168.2 2.5e-41 NP_001229789 (OMIM: 176892) cAMP-dependent protein ( 357) 2112 168.2 2.5e-41 NP_001229786 (OMIM: 176892) cAMP-dependent protein ( 358) 2112 168.2 2.5e-41 XP_005271073 (OMIM: 176892) PREDICTED: cAMP-depend ( 349) 2110 168.0 2.8e-41 NP_891993 (OMIM: 176892) cAMP-dependent protein ki ( 398) 2111 168.2 2.8e-41 NP_001229787 (OMIM: 176892) cAMP-dependent protein ( 339) 2106 167.7 3.3e-41 NP_002723 (OMIM: 176893,616176) cAMP-dependent pro ( 351) 2021 161.6 2.4e-39 NP_001229791 (OMIM: 176892) cAMP-dependent protein ( 338) 1988 159.2 1.2e-38 XP_016882437 (OMIM: 601639,615830) PREDICTED: cAMP ( 296) 1708 138.9 1.3e-32 XP_016857202 (OMIM: 176892) PREDICTED: cAMP-depend ( 258) 1585 130.0 5.7e-30 NP_001229790 (OMIM: 176892) cAMP-dependent protein ( 321) 1585 130.1 6.5e-30 NP_997461 (OMIM: 176892) cAMP-dependent protein ki ( 257) 1581 129.7 7e-30 XP_016857199 (OMIM: 176892) PREDICTED: cAMP-depend ( 261) 1518 125.2 1.6e-28 XP_016857198 (OMIM: 176892) PREDICTED: cAMP-depend ( 262) 1518 125.2 1.6e-28 XP_016857208 (OMIM: 176892) PREDICTED: cAMP-depend ( 245) 1514 124.8 1.9e-28 XP_016857201 (OMIM: 176892) PREDICTED: cAMP-depend ( 260) 1514 124.9 2e-28 XP_016857200 (OMIM: 176892) PREDICTED: cAMP-depend ( 261) 1514 124.9 2e-28 XP_016857206 (OMIM: 176892) PREDICTED: cAMP-depend ( 252) 1512 124.7 2.2e-28 XP_016857205 (OMIM: 176892) PREDICTED: cAMP-depend ( 253) 1512 124.7 2.2e-28 NP_001287844 (OMIM: 176892) cAMP-dependent protein ( 264) 1511 124.7 2.3e-28 XP_016857195 (OMIM: 176892) PREDICTED: cAMP-depend ( 265) 1511 124.7 2.4e-28 XP_016857209 (OMIM: 176892) PREDICTED: cAMP-depend ( 244) 1510 124.5 2.4e-28 XP_016857203 (OMIM: 176892) PREDICTED: cAMP-depend ( 256) 1509 124.5 2.6e-28 XP_005271077 (OMIM: 176892) PREDICTED: cAMP-depend ( 305) 1510 124.7 2.7e-28 XP_016857197 (OMIM: 176892) PREDICTED: cAMP-depend ( 263) 1507 124.4 2.9e-28 XP_016857196 (OMIM: 176892) PREDICTED: cAMP-depend ( 264) 1507 124.4 2.9e-28 XP_016857207 (OMIM: 176892) PREDICTED: cAMP-depend ( 246) 1505 124.2 3e-28 XP_016857204 (OMIM: 176892) PREDICTED: cAMP-depend ( 255) 1505 124.2 3.1e-28 NP_001287845 (OMIM: 176892) cAMP-dependent protein ( 304) 1506 124.4 3.3e-28 NP_001287846 (OMIM: 176892) cAMP-dependent protein ( 245) 1501 123.9 3.7e-28 NP_005035 (OMIM: 300083) cAMP-dependent protein ki ( 358) 1235 105.0 2.7e-22 NP_001269409 (OMIM: 601591) cGMP-dependent protein ( 342) 953 84.6 3.5e-16 NP_001269410 (OMIM: 601591) cGMP-dependent protein ( 342) 953 84.6 3.5e-16 NP_006250 (OMIM: 601591) cGMP-dependent protein ki ( 762) 953 85.1 5.4e-16 XP_005263183 (OMIM: 601591) PREDICTED: cGMP-depend ( 762) 953 85.1 5.4e-16 XP_016871902 (OMIM: 176894,615436) PREDICTED: cGMP ( 585) 948 84.6 5.9e-16 XP_016871901 (OMIM: 176894,615436) PREDICTED: cGMP ( 591) 948 84.6 6e-16 NP_001091982 (OMIM: 176894,615436) cGMP-dependent ( 671) 948 84.7 6.4e-16 NP_006249 (OMIM: 176894,615436) cGMP-dependent pro ( 686) 948 84.7 6.5e-16 NP_859029 (OMIM: 611223,615937) RAC-gamma serine/t ( 465) 909 81.6 3.7e-15 NP_001193658 (OMIM: 611223,615937) RAC-gamma serin ( 465) 909 81.6 3.7e-15 >>NP_002721 (OMIM: 601639,615830) cAMP-dependent protein (351 aa) initn: 2349 init1: 2349 opt: 2349 Z-score: 955.3 bits: 185.2 E(85289): 1.8e-46 Smith-Waterman score: 2349; 100.0% identity (100.0% similar) in 351 aa overlap (1-351:1-351) 10 20 30 40 50 60 pF1KB6 MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVML 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 VKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 VKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFAT 250 260 270 280 290 300 310 320 330 340 350 pF1KB6 TDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF ::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 TDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 310 320 330 340 350 >>NP_997401 (OMIM: 601639,615830) cAMP-dependent protein (343 aa) initn: 2262 init1: 2262 opt: 2262 Z-score: 921.5 bits: 179.0 E(85289): 1.4e-44 Smith-Waterman score: 2262; 98.8% identity (99.7% similar) in 341 aa overlap (11-351:3-343) 10 20 30 40 50 60 pF1KB6 MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVML :.. .::::::::::::::::::::::::::::::::::::::::::::: NP_997 MASNSSDVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVML 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 VKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 VKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMV 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGY 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB6 IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB6 ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFAT 240 250 260 270 280 290 310 320 330 340 350 pF1KB6 TDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF ::::::::::::::::::::::::::::::::::::::::::::::::::: NP_997 TDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 300 310 320 330 340 >>NP_001291278 (OMIM: 601639,615830) cAMP-dependent prot (427 aa) initn: 2258 init1: 2258 opt: 2258 Z-score: 919.0 bits: 178.8 E(85289): 1.9e-44 Smith-Waterman score: 2258; 100.0% identity (100.0% similar) in 336 aa overlap (16-351:92-427) 10 20 30 40 pF1KB6 MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWESPAQNTAHLDQFE :::::::::::::::::::::::::::::: NP_001 PGLPREGARGTAKSQGYKYLGWRRPWPWNVVKEFLAKAKEDFLKKWESPAQNTAHLDQFE 70 80 90 100 110 120 50 60 70 80 90 100 pF1KB6 RIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLV 130 140 150 160 170 180 110 120 130 140 150 160 pF1KB6 KLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIY 190 200 210 220 230 240 170 180 190 200 210 220 pF1KB6 RDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWAL 250 260 270 280 290 300 230 240 250 260 270 280 pF1KB6 GVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNL 310 320 330 340 350 360 290 300 310 320 330 340 pF1KB6 KNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCG 370 380 390 400 410 420 350 pF1KB6 KEFSEF :::::: NP_001 KEFSEF >>NP_002722 (OMIM: 176892) cAMP-dependent protein kinase (351 aa) initn: 2186 init1: 2186 opt: 2186 Z-score: 891.8 bits: 173.5 E(85289): 6.2e-43 Smith-Waterman score: 2186; 92.9% identity (98.3% similar) in 351 aa overlap (1-351:1-351) 10 20 30 40 50 60 pF1KB6 MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVML :::::.:::::: :::::::::::::::::::.:.::.: :..::: ::::::::::::: NP_002 MGNAATAKKGSEVESVKEFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVML 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 VKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMV :::: : ..::::::::::::::::::::::::::::::::::::.::..:::::::::: NP_002 VKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGY ::::::::::::::::::::::::::::::::::::::::::::::::::::::::.::: NP_002 MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFAT :::::::::::::::::::::::::::::::::::::::::::::::::.:::.:::::: NP_002 ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFAT 250 260 270 280 290 300 310 320 330 340 350 pF1KB6 TDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF :::::::::::::::::::.: ::::::::::::.:::::.:::.:::.:: NP_002 TDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEEDIRVSITEKCAKEFGEF 310 320 330 340 350 >>XP_006710821 (OMIM: 176892) PREDICTED: cAMP-dependent (354 aa) initn: 2119 init1: 2119 opt: 2119 Z-score: 865.6 bits: 168.7 E(85289): 1.8e-41 Smith-Waterman score: 2119; 91.3% identity (97.4% similar) in 346 aa overlap (6-351:9-354) 10 20 30 40 50 pF1KB6 MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGR :. .: . ::::::::::::::::::.:.::.: :..::: :::::::::: XP_006 MSARKSSDASACSSSEISVKEFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGR 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 VMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNL ::::::: : ..::::::::::::::::::::::::::::::::::::.::..::::::: XP_006 VMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNL 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 YMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::. XP_006 YMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDH 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB6 QGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 QGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYP 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB6 PFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKW ::::::::::::::::::::::::::::::::::::::::::::::::::::.:::.::: XP_006 PFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKW 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB6 FATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF ::::::::::::::::::::::.: ::::::::::::.:::::.:::.:::.:: XP_006 FATTDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEEDIRVSITEKCAKEFGEF 310 320 330 340 350 >>NP_001229788 (OMIM: 176892) cAMP-dependent protein kin (355 aa) initn: 2119 init1: 2119 opt: 2119 Z-score: 865.6 bits: 168.7 E(85289): 1.8e-41 Smith-Waterman score: 2119; 91.3% identity (97.4% similar) in 346 aa overlap (6-351:10-355) 10 20 30 40 50 pF1KB6 MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFG :. .: . ::::::::::::::::::.:.::.: :..::: ::::::::: NP_001 MGLSRKSSDASACSSSEISVKEFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFG 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 RVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSN :::::::: : ..::::::::::::::::::::::::::::::::::::.::..:::::: NP_001 RVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSN 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 LYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLID 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB6 QQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGY .::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGY 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB6 PPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHK :::::::::::::::::::::::::::::::::::::::::::::::::::::.:::.:: NP_001 PPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHK 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB6 WFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF :::::::::::::::::::::::.: ::::::::::::.:::::.:::.:::.:: NP_001 WFATTDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEEDIRVSITEKCAKEFGEF 310 320 330 340 350 >>XP_005271075 (OMIM: 176892) PREDICTED: cAMP-dependent (346 aa) initn: 2117 init1: 2117 opt: 2117 Z-score: 865.0 bits: 168.5 E(85289): 1.9e-41 Smith-Waterman score: 2117; 92.4% identity (97.9% similar) in 341 aa overlap (11-351:6-346) 10 20 30 40 50 60 pF1KB6 MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVML : . ::::::::::::::::::.:.::.: :..::: ::::::::::::: XP_005 MSACSSSEISVKEFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVML 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 VKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMV :::: : ..::::::::::::::::::::::::::::::::::::.::..:::::::::: XP_005 VKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMV 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGY ::::::::::::::::::::::::::::::::::::::::::::::::::::::::.::: XP_005 MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGY 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB6 IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB6 ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFAT :::::::::::::::::::::::::::::::::::::::::::::::::.:::.:::::: XP_005 ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFAT 240 250 260 270 280 290 310 320 330 340 350 pF1KB6 TDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF :::::::::::::::::::.: ::::::::::::.:::::.:::.:::.:: XP_005 TDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEEDIRVSITEKCAKEFGEF 300 310 320 330 340 >>XP_005271074 (OMIM: 176892) PREDICTED: cAMP-dependent (347 aa) initn: 2117 init1: 2117 opt: 2117 Z-score: 864.9 bits: 168.5 E(85289): 1.9e-41 Smith-Waterman score: 2117; 92.4% identity (97.9% similar) in 341 aa overlap (11-351:7-347) 10 20 30 40 50 60 pF1KB6 MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVML : . ::::::::::::::::::.:.::.: :..::: ::::::::::::: XP_005 MGLSCSSSEISVKEFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVML 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 VKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMV :::: : ..::::::::::::::::::::::::::::::::::::.::..:::::::::: XP_005 VKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMV 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGY ::::::::::::::::::::::::::::::::::::::::::::::::::::::::.::: XP_005 MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGY 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB6 IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB6 ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFAT :::::::::::::::::::::::::::::::::::::::::::::::::.:::.:::::: XP_005 ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFAT 240 250 260 270 280 290 310 320 330 340 350 pF1KB6 TDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF :::::::::::::::::::.: ::::::::::::.:::::.:::.:::.:: XP_005 TDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEEDIRVSITEKCAKEFGEF 300 310 320 330 340 >>XP_005271076 (OMIM: 176892) PREDICTED: cAMP-dependent (338 aa) initn: 2115 init1: 2115 opt: 2115 Z-score: 864.3 bits: 168.4 E(85289): 2.1e-41 Smith-Waterman score: 2115; 93.2% identity (98.5% similar) in 337 aa overlap (15-351:2-338) 10 20 30 40 50 60 pF1KB6 MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVML ::::::::::::::::::.:.::.: :..::: ::::::::::::: XP_005 MSVKEFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVML 10 20 30 40 70 80 90 100 110 120 pF1KB6 VKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMV :::: : ..::::::::::::::::::::::::::::::::::::.::..:::::::::: XP_005 VKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMV 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB6 MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGY ::::::::::::::::::::::::::::::::::::::::::::::::::::::::.::: XP_005 MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGY 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB6 IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB6 ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFAT :::::::::::::::::::::::::::::::::::::::::::::::::.:::.:::::: XP_005 ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFAT 230 240 250 260 270 280 310 320 330 340 350 pF1KB6 TDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF :::::::::::::::::::.: ::::::::::::.:::::.:::.:::.:: XP_005 TDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEEDIRVSITEKCAKEFGEF 290 300 310 320 330 >>XP_005271072 (OMIM: 176892) PREDICTED: cAMP-dependent (350 aa) initn: 2110 init1: 2110 opt: 2112 Z-score: 863.0 bits: 168.2 E(85289): 2.5e-41 Smith-Waterman score: 2112; 90.0% identity (97.2% similar) in 351 aa overlap (1-351:1-350) 10 20 30 40 50 60 pF1KB6 MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVML :: . .... :.. :::::::::::::::::.:.::.: :..::: ::::::::::::: XP_005 MGLSCSSSEISDSF-VKEFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVML 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 VKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMV :::: : ..::::::::::::::::::::::::::::::::::::.::..:::::::::: XP_005 VKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMV 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGY ::::::::::::::::::::::::::::::::::::::::::::::::::::::::.::: XP_005 MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGY 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB6 IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB6 ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFAT :::::::::::::::::::::::::::::::::::::::::::::::::.:::.:::::: XP_005 ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFAT 240 250 260 270 280 290 310 320 330 340 350 pF1KB6 TDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF :::::::::::::::::::.: ::::::::::::.:::::.:::.:::.:: XP_005 TDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEEDIRVSITEKCAKEFGEF 300 310 320 330 340 350 351 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 17:24:17 2016 done: Fri Nov 4 17:24:18 2016 Total Scan time: 6.800 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]