FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6461, 321 aa 1>>>pF1KB6461 321 - 321 aa - 321 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.4825+/-0.000321; mu= 12.0393+/- 0.020 mean_var=130.6867+/-25.083, 0's: 0 Z-trim(120.0): 277 B-trim: 135 in 2/50 Lambda= 0.112191 statistics sampled from 34498 (34801) to 34498 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.77), E-opt: 0.2 (0.408), width: 16 Scan time: 8.570 The best scores are: opt bits E(85289) XP_005272519 (OMIM: 151445) PREDICTED: low affinit ( 321) 2221 370.3 3.1e-102 NP_001993 (OMIM: 151445) low affinity immunoglobul ( 321) 2221 370.3 3.1e-102 NP_001207429 (OMIM: 151445) low affinity immunoglo ( 321) 2221 370.3 3.1e-102 NP_001193948 (OMIM: 151445) low affinity immunoglo ( 320) 2174 362.7 5.9e-100 NP_001231785 (OMIM: 616256) C-type lectin domain f ( 281) 438 81.6 2.1e-15 NP_940894 (OMIM: 616256) C-type lectin domain fami ( 293) 438 81.6 2.1e-15 NP_001138379 (OMIM: 605872) C-type lectin domain f ( 332) 402 75.9 1.3e-13 NP_001138378 (OMIM: 605872) C-type lectin domain f ( 263) 399 75.3 1.6e-13 NP_001138381 (OMIM: 605872) C-type lectin domain f ( 353) 388 73.6 6.7e-13 XP_006722677 (OMIM: 605872) PREDICTED: C-type lect ( 343) 381 72.5 1.4e-12 NP_001138376 (OMIM: 605872) C-type lectin domain f ( 348) 381 72.5 1.5e-12 XP_006722675 (OMIM: 605872) PREDICTED: C-type lect ( 371) 381 72.5 1.5e-12 XP_006722676 (OMIM: 605872) PREDICTED: C-type lect ( 371) 381 72.5 1.5e-12 NP_001138377 (OMIM: 605872) C-type lectin domain f ( 375) 381 72.5 1.5e-12 NP_001138382 (OMIM: 605872) C-type lectin domain f ( 376) 381 72.5 1.5e-12 NP_001316999 (OMIM: 605999) C-type lectin domain f ( 289) 379 72.1 1.6e-12 XP_006721587 (OMIM: 108361) PREDICTED: asialoglyco ( 248) 378 71.9 1.6e-12 NP_550436 (OMIM: 108361) asialoglycoprotein recept ( 292) 379 72.1 1.6e-12 XP_006722674 (OMIM: 605872) PREDICTED: C-type lect ( 398) 381 72.5 1.6e-12 NP_055072 (OMIM: 605872) C-type lectin domain fami ( 399) 381 72.5 1.6e-12 NP_550434 (OMIM: 108361) asialoglycoprotein recept ( 311) 379 72.1 1.7e-12 NP_001172 (OMIM: 108361) asialoglycoprotein recept ( 311) 379 72.1 1.7e-12 XP_016882280 (OMIM: 616838) PREDICTED: C-type lect ( 243) 377 71.7 1.8e-12 XP_016880140 (OMIM: 108361) PREDICTED: asialoglyco ( 292) 377 71.8 2e-12 XP_016882279 (OMIM: 616838) PREDICTED: C-type lect ( 293) 377 71.8 2e-12 XP_016882277 (OMIM: 616838) PREDICTED: C-type lect ( 310) 377 71.8 2.1e-12 XP_016882274 (OMIM: 616838) PREDICTED: C-type lect ( 310) 377 71.8 2.1e-12 XP_016882275 (OMIM: 616838) PREDICTED: C-type lect ( 310) 377 71.8 2.1e-12 XP_016882276 (OMIM: 616838) PREDICTED: C-type lect ( 310) 377 71.8 2.1e-12 XP_016882278 (OMIM: 616838) PREDICTED: C-type lect ( 310) 377 71.8 2.1e-12 XP_016880141 (OMIM: 108361) PREDICTED: asialoglyco ( 311) 377 71.8 2.1e-12 XP_016880142 (OMIM: 108361) PREDICTED: asialoglyco ( 311) 377 71.8 2.1e-12 NP_006335 (OMIM: 605999) C-type lectin domain fami ( 292) 376 71.6 2.2e-12 NP_001138365 (OMIM: 604672,607948,609423,614371) C ( 268) 375 71.4 2.4e-12 NP_001191047 (OMIM: 616838) C-type lectin domain f ( 378) 377 71.9 2.4e-12 XP_006721589 (OMIM: 108361) PREDICTED: asialoglyco ( 287) 367 70.1 6.1e-12 NP_550435 (OMIM: 108361) asialoglycoprotein recept ( 287) 367 70.1 6.1e-12 XP_005256705 (OMIM: 108361) PREDICTED: asialoglyco ( 287) 367 70.1 6.1e-12 NP_001188281 (OMIM: 108361) asialoglycoprotein rec ( 306) 367 70.2 6.4e-12 NP_001138367 (OMIM: 604672,607948,609423,614371) C ( 312) 367 70.2 6.5e-12 XP_011522168 (OMIM: 108361) PREDICTED: asialoglyco ( 299) 365 69.8 7.8e-12 XP_011522165 (OMIM: 108361) PREDICTED: asialoglyco ( 299) 365 69.8 7.8e-12 XP_011522167 (OMIM: 108361) PREDICTED: asialoglyco ( 299) 365 69.8 7.8e-12 XP_011522166 (OMIM: 108361) PREDICTED: asialoglyco ( 318) 365 69.8 8.2e-12 NP_001184145 (OMIM: 108360) asialoglycoprotein rec ( 252) 363 69.4 8.7e-12 NP_001662 (OMIM: 108360) asialoglycoprotein recept ( 291) 363 69.5 9.6e-12 XP_011522163 (OMIM: 108360) PREDICTED: asialoglyco ( 291) 363 69.5 9.6e-12 XP_011522164 (OMIM: 108361) PREDICTED: asialoglyco ( 410) 365 69.9 9.9e-12 XP_005272529 (OMIM: 604672,607948,609423,614371) P ( 266) 355 68.2 2.2e-11 NP_001138366 (OMIM: 604672,607948,609423,614371) C ( 360) 351 67.6 4.3e-11 >>XP_005272519 (OMIM: 151445) PREDICTED: low affinity im (321 aa) initn: 2221 init1: 2221 opt: 2221 Z-score: 1956.6 bits: 370.3 E(85289): 3.1e-102 Smith-Waterman score: 2221; 99.7% identity (100.0% similar) in 321 aa overlap (1-321:1-321) 10 20 30 40 50 60 pF1KB6 MEEGQYSEIEELPRRRCCRRGTQIVLLGLVTAALWAGLLTLLLLWHWDTTQSLKQLEERA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MEEGQYSEIEELPRRRCCRRGTQIVLLGLVTAALWAGLLTLLLLWHWDTTQSLKQLEERA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 ARNVSQVSKNLESHHGDQMAQKSQSTQISQELEELRAEQQRLKSQDLELSWNLNGLQADL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ARNVSQVSKNLESHHGDQMAQKSQSTQISQELEELRAEQQRLKSQDLELSWNLNGLQADL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 SSFKSQELNERNEASDLLERLREEVTKLRMELQVSSGFVCNTCPEKWINFQRKCYYFGKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SSFKSQELNERNEASDLLERLREEVTKLRMELQVSSGFVCNTCPEKWINFQRKCYYFGKG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 TKQWVHARYACDDMEGQLVSIHSPEEQDFLTKHASHTGSWIGLRNLDLKGEFIWVDGSHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TKQWVHARYACDDMEGQLVSIHSPEEQDFLTKHASHTGSWIGLRNLDLKGEFIWVDGSHV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 DYSNWAPGEPTSRSQGEDCVMMRGSGRWNDAFCDRKLGAWVCDQLATCTPPASEGSAESM :::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::: XP_005 DYSNWAPGEPTSRSQGEDCVMMRGSGRWNDAFCDRKLGAWVCDRLATCTPPASEGSAESM 250 260 270 280 290 300 310 320 pF1KB6 GPDSRPDPDGRLPTPSAPLHS ::::::::::::::::::::: XP_005 GPDSRPDPDGRLPTPSAPLHS 310 320 >>NP_001993 (OMIM: 151445) low affinity immunoglobulin e (321 aa) initn: 2221 init1: 2221 opt: 2221 Z-score: 1956.6 bits: 370.3 E(85289): 3.1e-102 Smith-Waterman score: 2221; 99.7% identity (100.0% similar) in 321 aa overlap (1-321:1-321) 10 20 30 40 50 60 pF1KB6 MEEGQYSEIEELPRRRCCRRGTQIVLLGLVTAALWAGLLTLLLLWHWDTTQSLKQLEERA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MEEGQYSEIEELPRRRCCRRGTQIVLLGLVTAALWAGLLTLLLLWHWDTTQSLKQLEERA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 ARNVSQVSKNLESHHGDQMAQKSQSTQISQELEELRAEQQRLKSQDLELSWNLNGLQADL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ARNVSQVSKNLESHHGDQMAQKSQSTQISQELEELRAEQQRLKSQDLELSWNLNGLQADL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 SSFKSQELNERNEASDLLERLREEVTKLRMELQVSSGFVCNTCPEKWINFQRKCYYFGKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSFKSQELNERNEASDLLERLREEVTKLRMELQVSSGFVCNTCPEKWINFQRKCYYFGKG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 TKQWVHARYACDDMEGQLVSIHSPEEQDFLTKHASHTGSWIGLRNLDLKGEFIWVDGSHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TKQWVHARYACDDMEGQLVSIHSPEEQDFLTKHASHTGSWIGLRNLDLKGEFIWVDGSHV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 DYSNWAPGEPTSRSQGEDCVMMRGSGRWNDAFCDRKLGAWVCDQLATCTPPASEGSAESM :::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::: NP_001 DYSNWAPGEPTSRSQGEDCVMMRGSGRWNDAFCDRKLGAWVCDRLATCTPPASEGSAESM 250 260 270 280 290 300 310 320 pF1KB6 GPDSRPDPDGRLPTPSAPLHS ::::::::::::::::::::: NP_001 GPDSRPDPDGRLPTPSAPLHS 310 320 >>NP_001207429 (OMIM: 151445) low affinity immunoglobuli (321 aa) initn: 2221 init1: 2221 opt: 2221 Z-score: 1956.6 bits: 370.3 E(85289): 3.1e-102 Smith-Waterman score: 2221; 99.7% identity (100.0% similar) in 321 aa overlap (1-321:1-321) 10 20 30 40 50 60 pF1KB6 MEEGQYSEIEELPRRRCCRRGTQIVLLGLVTAALWAGLLTLLLLWHWDTTQSLKQLEERA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MEEGQYSEIEELPRRRCCRRGTQIVLLGLVTAALWAGLLTLLLLWHWDTTQSLKQLEERA 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 ARNVSQVSKNLESHHGDQMAQKSQSTQISQELEELRAEQQRLKSQDLELSWNLNGLQADL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ARNVSQVSKNLESHHGDQMAQKSQSTQISQELEELRAEQQRLKSQDLELSWNLNGLQADL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 SSFKSQELNERNEASDLLERLREEVTKLRMELQVSSGFVCNTCPEKWINFQRKCYYFGKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSFKSQELNERNEASDLLERLREEVTKLRMELQVSSGFVCNTCPEKWINFQRKCYYFGKG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 TKQWVHARYACDDMEGQLVSIHSPEEQDFLTKHASHTGSWIGLRNLDLKGEFIWVDGSHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TKQWVHARYACDDMEGQLVSIHSPEEQDFLTKHASHTGSWIGLRNLDLKGEFIWVDGSHV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 DYSNWAPGEPTSRSQGEDCVMMRGSGRWNDAFCDRKLGAWVCDQLATCTPPASEGSAESM :::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::: NP_001 DYSNWAPGEPTSRSQGEDCVMMRGSGRWNDAFCDRKLGAWVCDRLATCTPPASEGSAESM 250 260 270 280 290 300 310 320 pF1KB6 GPDSRPDPDGRLPTPSAPLHS ::::::::::::::::::::: NP_001 GPDSRPDPDGRLPTPSAPLHS 310 320 >>NP_001193948 (OMIM: 151445) low affinity immunoglobuli (320 aa) initn: 2174 init1: 2174 opt: 2174 Z-score: 1915.5 bits: 362.7 E(85289): 5.9e-100 Smith-Waterman score: 2174; 99.7% identity (100.0% similar) in 314 aa overlap (8-321:7-320) 10 20 30 40 50 60 pF1KB6 MEEGQYSEIEELPRRRCCRRGTQIVLLGLVTAALWAGLLTLLLLWHWDTTQSLKQLEERA ::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MNPPSQEIEELPRRRCCRRGTQIVLLGLVTAALWAGLLTLLLLWHWDTTQSLKQLEERA 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 ARNVSQVSKNLESHHGDQMAQKSQSTQISQELEELRAEQQRLKSQDLELSWNLNGLQADL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ARNVSQVSKNLESHHGDQMAQKSQSTQISQELEELRAEQQRLKSQDLELSWNLNGLQADL 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 SSFKSQELNERNEASDLLERLREEVTKLRMELQVSSGFVCNTCPEKWINFQRKCYYFGKG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SSFKSQELNERNEASDLLERLREEVTKLRMELQVSSGFVCNTCPEKWINFQRKCYYFGKG 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB6 TKQWVHARYACDDMEGQLVSIHSPEEQDFLTKHASHTGSWIGLRNLDLKGEFIWVDGSHV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TKQWVHARYACDDMEGQLVSIHSPEEQDFLTKHASHTGSWIGLRNLDLKGEFIWVDGSHV 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB6 DYSNWAPGEPTSRSQGEDCVMMRGSGRWNDAFCDRKLGAWVCDQLATCTPPASEGSAESM :::::::::::::::::::::::::::::::::::::::::::.:::::::::::::::: NP_001 DYSNWAPGEPTSRSQGEDCVMMRGSGRWNDAFCDRKLGAWVCDRLATCTPPASEGSAESM 240 250 260 270 280 290 310 320 pF1KB6 GPDSRPDPDGRLPTPSAPLHS ::::::::::::::::::::: NP_001 GPDSRPDPDGRLPTPSAPLHS 300 310 320 >>NP_001231785 (OMIM: 616256) C-type lectin domain famil (281 aa) initn: 448 init1: 196 opt: 438 Z-score: 397.6 bits: 81.6 E(85289): 2.1e-15 Smith-Waterman score: 438; 29.7% identity (56.8% similar) in 273 aa overlap (19-288:17-281) 10 20 30 40 50 60 pF1KB6 MEEGQYSEIEELPRRRCCRRGTQIVLLGLVTAALWAGLLTLLLLWHWDTTQSLKQLEERA :: ..: :::..::: .:..:: .: . .. NP_001 MDTTRYRPWGRWVHWSRRPLFLALAVLVTTVLWAVILSILLSKASTERAALLDGHDLL 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 ARNVSQVSKNLESHHGDQMAQKSQSTQISQELEELRAEQQRLKSQDLELSWNLNGLQADL :.:. . : . . . .: . . .:. ::: . ... .: : :. . NP_001 RTNASKQTAALGALKEEVGDCHSCCSGTQAQLQTTRAELGEAQAKLMEQESALRELRERV 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 SSFKSQELNERNEASDLLERLREEVTKLRMELQVSSGFVCNTCPEKWINFQRKCYYFGKG .. .. :... : : : : .:: .: :. :: .:..:. .::.:. NP_001 TQGLAEAGRGREDVRTELFRALEAV-----RLQNNS---CEPCPTSWLSFEGSCYFFSVP 120 130 140 150 160 170 190 200 210 220 230 pF1KB6 TKQWVHARYACDDMEGQLVSIHSPEEQDFLTKHASHTGSWIGLRNLDLKGE---FIWVDG :. :. : : ..:: . . .:: :::... : :.::: . :. . :::: NP_001 KTTWAAAQDHCADASAHLVIVGGLDEQGFLTRNTRGRGYWLGLRAVRHLGKVQGYQWVDG 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB6 SHVDYSNWAPGEPTSRSQGEDCVMMRGSGRWNDAFCDRKLGAWVCDQLATCTPPASEGSA ...:.: :::.. :.:::: .: :::: :: . .:.:.. .: NP_001 VSLSFSHWNQGEPNDAWGRENCVMMLHTGLWNDAPCDSEKDGWICEKRHNC 240 250 260 270 280 300 310 320 pF1KB6 ESMGPDSRPDPDGRLPTPSAPLHS >>NP_940894 (OMIM: 616256) C-type lectin domain family 4 (293 aa) initn: 448 init1: 196 opt: 438 Z-score: 397.4 bits: 81.6 E(85289): 2.1e-15 Smith-Waterman score: 438; 29.7% identity (56.8% similar) in 273 aa overlap (19-288:29-293) 10 20 30 40 50 pF1KB6 MEEGQYSEIEELPRRRCCRRGTQIVLLGLVTAALWAGLLTLLLLWHWDTT :: ..: :::..::: .:..:: NP_940 MDTTRYSKWGGSSEEVPGGPWGRWVHWSRRPLFLALAVLVTTVLWAVILSILLSKASTER 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 QSLKQLEERAARNVSQVSKNLESHHGDQMAQKSQSTQISQELEELRAEQQRLKSQDLELS .: . .. :.:. . : . . . .: . . .:. ::: . ... .: NP_940 AALLDGHDLLRTNASKQTAALGALKEEVGDCHSCCSGTQAQLQTTRAELGEAQAKLMEQE 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 WNLNGLQADLSSFKSQELNERNEASDLLERLREEVTKLRMELQVSSGFVCNTCPEKWINF : :. ... .. :... : : : : .:: .: :. :: .:..: NP_940 SALRELRERVTQGLAEAGRGREDVRTELFRALEAV-----RLQNNS---CEPCPTSWLSF 130 140 150 160 170 180 190 200 210 220 230 pF1KB6 QRKCYYFGKGTKQWVHARYACDDMEGQLVSIHSPEEQDFLTKHASHTGSWIGLRNLDLKG . .::.:. :. :. : : ..:: . . .:: :::... : :.::: . : NP_940 EGSCYFFSVPKTTWAAAQDHCADASAHLVIVGGLDEQGFLTRNTRGRGYWLGLRAVRHLG 180 190 200 210 220 230 240 250 260 270 280 pF1KB6 E---FIWVDGSHVDYSNWAPGEPTSRSQGEDCVMMRGSGRWNDAFCDRKLGAWVCDQLAT . . :::: ...:.: :::.. :.:::: .: :::: :: . .:.:.. . NP_940 KVQGYQWVDGVSLSFSHWNQGEPNDAWGRENCVMMLHTGLWNDAPCDSEKDGWICEKRHN 240 250 260 270 280 290 290 300 310 320 pF1KB6 CTPPASEGSAESMGPDSRPDPDGRLPTPSAPLHS : NP_940 C >>NP_001138379 (OMIM: 605872) C-type lectin domain famil (332 aa) initn: 347 init1: 169 opt: 402 Z-score: 365.2 bits: 75.9 E(85289): 1.3e-13 Smith-Waterman score: 422; 33.3% identity (63.9% similar) in 249 aa overlap (57-288:84-328) 30 40 50 60 70 80 pF1KB6 LGLVTAALWAGLLTLLLLWHWDTTQSLKQLEERAARNVSQVSKNLESHHGDQMAQKSQST :. ... : .:.. :. . .::. NP_001 VPSSLSQEQSEQDAIYQNLTQLKAAVGELSEKSKLQEIYQELTQLKAAVGE-LPEKSKLQ 60 70 80 90 100 110 90 100 110 120 130 pF1KB6 QISQELEELRAEQQRL--KSQDLELSWNLNGLQADLSSF--KS------QELNERNEA-S .: ::: .:.: .: ::. :. .:. :.: .. . :: :::.: . : . NP_001 EIYQELTRLKAAVGELPEKSKLQEIYQELTRLKAAVGELPEKSKLQEIYQELTELKAAVG 120 130 140 150 160 170 140 150 160 170 180 190 pF1KB6 DLLERLR-EEVTKLRMELQVSSGFVCNTCPEKWINFQRKCYYFGKGTKQWVHARYACDDM .: :. . .:. . .:... .: ::. : :: .::..... ..: . ::... NP_001 ELPEKSKLQEIYQELTQLKAAVERLCRHCPKDWTFFQGNCYFMSNSQRNWHDSVTACQEV 180 190 200 210 220 230 200 210 220 230 240 pF1KB6 EGQLVSIHSPEEQDFLTKHASHTG--SWIGLRNLDLKGEFIWVDGSHVDYS---NWAPGE ..::: :.. :::.:: ..:... ::.:: .:. .: . ::::: .. : : :: NP_001 RAQLVVIKTAEEQNFLQLQTSRSNRFSWMGLSDLNQEGTWQWVDGSPLSPSFQRYWNSGE 240 250 260 270 280 290 250 260 270 280 290 300 pF1KB6 PTSRSQGEDCVMMRGSGRWNDAFCDRKLGAWVCDQLATCTPPASEGSAESMGPDSRPDPD :.. : .:::. . ::: ::: :: . :.: . :.: NP_001 PNN-SGNEDCAEFSGSG-WNDNRCDVD-NYWICKKPAACFRDE 300 310 320 330 310 320 pF1KB6 GRLPTPSAPLHS >>NP_001138378 (OMIM: 605872) C-type lectin domain famil (263 aa) initn: 343 init1: 169 opt: 399 Z-score: 363.9 bits: 75.3 E(85289): 1.6e-13 Smith-Waterman score: 412; 33.0% identity (66.1% similar) in 230 aa overlap (64-288:51-259) 40 50 60 70 80 90 pF1KB6 LWAGLLTLLLLWHWDTTQSLKQLEERAARNVSQVSKNLESHHGDQMAQKSQSTQISQELE ::.: ..: .....: : .. ::.. . NP_001 TSGIRLFPRDFQFQQIHGHKSSTVPFLLGPVSKVPSSLSQEQSEQDAIYQNLTQLKAAVG 30 40 50 60 70 80 100 110 120 130 140 150 pF1KB6 ELRAEQQRLKSQDLELSWNLNGLQADLSSFKSQELNERNEASDLLERLREEVTKLRMELQ :: .:...:. :. .:. :.: .. :: :... :... .:.:.:. .. NP_001 EL-SEKSKLQ----EIYQELTQLKAAVG-----ELPEKSK----LQEIYQELTRLKAAVE 90 100 110 120 160 170 180 190 200 210 pF1KB6 VSSGFVCNTCPEKWINFQRKCYYFGKGTKQWVHARYACDDMEGQLVSIHSPEEQDFLTKH .: ::. : :: .::..... ..: . ::.....::: :.. :::.:: . NP_001 R----LCRHCPKDWTFFQGNCYFMSNSQRNWHDSVTACQEVRAQLVVIKTAEEQNFLQLQ 130 140 150 160 170 180 220 230 240 250 260 pF1KB6 ASHTG--SWIGLRNLDLKGEFIWVDGSHVDYS---NWAPGEPTSRSQGEDCVMMRGSGRW .:... ::.:: .:. .: . ::::: .. : : :::.. : .:::. . ::: : NP_001 TSRSNRFSWMGLSDLNQEGTWQWVDGSPLSPSFQRYWNSGEPNN-SGNEDCAEFSGSG-W 190 200 210 220 230 240 270 280 290 300 310 320 pF1KB6 NDAFCDRKLGAWVCDQLATCTPPASEGSAESMGPDSRPDPDGRLPTPSAPLHS :: :: . :.: . :.: NP_001 NDNRCDVD-NYWICKKPAACFRDE 250 260 >>NP_001138381 (OMIM: 605872) C-type lectin domain famil (353 aa) initn: 335 init1: 169 opt: 388 Z-score: 352.6 bits: 73.6 E(85289): 6.7e-13 Smith-Waterman score: 421; 30.9% identity (60.2% similar) in 324 aa overlap (5-288:32-349) 10 20 30 pF1KB6 MEEGQYSEIEELPRRRCCRRGTQIVLLGLVTAAL :...:. : : ..: :.. : NP_001 SDSKEPRVQQLGLLEEDPTTSGIRLFPRDFQFQQIHGHKSSTGCL-GHGALVLQLLSFML 10 20 30 40 50 60 40 50 60 70 80 90 pF1KB6 WAGLLTLLLLWHWDTTQSLKQLEERAARNVSQVSKNLESHHGDQMAQKSQSTQISQELEE ::.:. .:. . .::.: :. . : .:.. :. ...::. .: ::: . NP_001 LAGVLVAILVQVSKVPSSLSQ-EQSEQDAIYQNLTQLKAAVGE-LSEKSKLQEIYQELTQ 70 80 90 100 110 100 110 120 130 pF1KB6 LRAEQQRL--KSQDLELSWNLNGLQADLSSF--KS------QELNERNEA-SDL-----L :.: .: ::. :. .:. :.: .. . :: :::.. . : ..: : NP_001 LKAAVGELPEKSKLQEIYQELTRLKAAVGELPEKSKLQEIYQELTRLKAAVGELPEKSKL 120 130 140 150 160 170 140 150 160 170 pF1KB6 ERLREEVTKLR----------------MEL-QVSSGF--VCNTCPEKWINFQRKCYYFGK ... .:.:.:. .:: .....: .: ::. : :: .::.... NP_001 QEIYQELTQLKAAVGELPDQSKQQQIYQELTDLKTAFERLCRHCPKDWTFFQGNCYFMSN 180 190 200 210 220 230 180 190 200 210 220 230 pF1KB6 GTKQWVHARYACDDMEGQLVSIHSPEEQDFLTKHASHTG--SWIGLRNLDLKGEFIWVDG . ..: . ::.....::: :.. :::.:: ..:... ::.:: .:. .: . :::: NP_001 SQRNWHDSVTACQEVRAQLVVIKTAEEQNFLQLQTSRSNRFSWMGLSDLNQEGTWQWVDG 240 250 260 270 280 290 240 250 260 270 280 290 pF1KB6 SHVDYS---NWAPGEPTSRSQGEDCVMMRGSGRWNDAFCDRKLGAWVCDQLATCTPPASE : .. : : :::.. : .:::. . ::: ::: :: . :.: . :.: NP_001 SPLSPSFQRYWNSGEPNN-SGNEDCAEFSGSG-WNDNRCDVD-NYWICKKPAACFRDE 300 310 320 330 340 350 300 310 320 pF1KB6 GSAESMGPDSRPDPDGRLPTPSAPLHS >>XP_006722677 (OMIM: 605872) PREDICTED: C-type lectin d (343 aa) initn: 347 init1: 169 opt: 381 Z-score: 346.6 bits: 72.5 E(85289): 1.4e-12 Smith-Waterman score: 413; 32.6% identity (62.8% similar) in 239 aa overlap (57-288:118-339) 30 40 50 60 70 80 pF1KB6 LGLVTAALWAGLLTLLLLWHWDTTQSLKQLEERAARNVSQVSKNLESHHGDQMAQKSQST :. ... : :.. :. . .::. XP_006 AAVGELPEKSKLQEIYQELTRLKAAVGELPEKSKLQEIYQELTRLKAAVGE-LPEKSKLQ 90 100 110 120 130 140 90 100 110 120 130 140 pF1KB6 QISQELEELRAEQQRL--KSQDLELSWNLNGLQADLSSFKSQELNERNEASDLLERLREE .: ::: ::.: .: ::. :. .:. :.: .. :: .... ... .: XP_006 EIYQELTELKAAVGELPEKSKLQEIYQELTQLKAAVG-----ELPDQSKQ----QQIYQE 150 160 170 180 190 150 160 170 180 190 200 pF1KB6 VTKLRMELQVSSGFVCNTCPEKWINFQRKCYYFGKGTKQWVHARYACDDMEGQLVSIHSP .: :. .. .: ::. : :: .::..... ..: . ::.....::: :.. XP_006 LTDLKTAFE----RLCRHCPKDWTFFQGNCYFMSNSQRNWHDSVTACQEVRAQLVVIKTA 200 210 220 230 240 250 210 220 230 240 250 pF1KB6 EEQDFLTKHASHTG--SWIGLRNLDLKGEFIWVDGSHVDYS---NWAPGEPTSRSQGEDC :::.:: ..:... ::.:: .:. .: . ::::: .. : : :::.. : .::: XP_006 EEQNFLQLQTSRSNRFSWMGLSDLNQEGTWQWVDGSPLSPSFQRYWNSGEPNN-SGNEDC 260 270 280 290 300 310 260 270 280 290 300 310 pF1KB6 VMMRGSGRWNDAFCDRKLGAWVCDQLATCTPPASEGSAESMGPDSRPDPDGRLPTPSAPL . . ::: ::: :: . :.: . :.: XP_006 AEFSGSG-WNDNRCDVD-NYWICKKPAACFRDE 320 330 340 321 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 01:13:59 2016 done: Sat Nov 5 01:14:00 2016 Total Scan time: 8.570 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]