FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6462, 352 aa
1>>>pF1KB6462 352 - 352 aa - 352 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.2678+/-0.00109; mu= 3.2378+/- 0.064
mean_var=191.8993+/-40.718, 0's: 0 Z-trim(109.4): 141 B-trim: 33 in 1/51
Lambda= 0.092584
statistics sampled from 10719 (10870) to 10719 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.701), E-opt: 0.2 (0.334), width: 16
Scan time: 2.430
The best scores are: opt bits E(32554)
CCDS6483.1 SH3GL2 gene_id:6456|Hs108|chr9 ( 352) 2330 323.6 1.5e-88
CCDS10325.2 SH3GL3 gene_id:6457|Hs108|chr15 ( 347) 1617 228.4 7e-60
CCDS73772.1 SH3GL3 gene_id:6457|Hs108|chr15 ( 355) 1532 217.1 1.9e-56
CCDS32874.1 SH3GL1 gene_id:6455|Hs108|chr19 ( 368) 1390 198.1 9.8e-51
CCDS56076.1 SH3GL1 gene_id:6455|Hs108|chr19 ( 320) 830 123.3 2.9e-28
CCDS59335.1 SH3GL1 gene_id:6455|Hs108|chr19 ( 304) 666 101.3 1.1e-21
>>CCDS6483.1 SH3GL2 gene_id:6456|Hs108|chr9 (352 aa)
initn: 2330 init1: 2330 opt: 2330 Z-score: 1703.2 bits: 323.6 E(32554): 1.5e-88
Smith-Waterman score: 2330; 100.0% identity (100.0% similar) in 352 aa overlap (1-352:1-352)
10 20 30 40 50 60
pF1KB6 MSVAGLKKQFHKATQKVSEKVGGAEGTKLDDDFKEMERKVDVTSRAVMEIMTKTIEYLQP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS64 MSVAGLKKQFHKATQKVSEKVGGAEGTKLDDDFKEMERKVDVTSRAVMEIMTKTIEYLQP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 NPASRAKLSMINTMSKIRGQEKGPGYPQAEALLAEAMLKFGRELGDDCNFGPALGEVGEA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS64 NPASRAKLSMINTMSKIRGQEKGPGYPQAEALLAEAMLKFGRELGDDCNFGPALGEVGEA
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 MRELSEVKDSLDIEVKQNFIDPLQNLHDKDLREIQHHLKKLEGRRLDFDYKKKRQGKIPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS64 MRELSEVKDSLDIEVKQNFIDPLQNLHDKDLREIQHHLKKLEGRRLDFDYKKKRQGKIPD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 EELRQALEKFDESKEIAESSMFNLLEMDIEQVSQLSALVQAQLEYHKQAVQILQQVTVRL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS64 EELRQALEKFDESKEIAESSMFNLLEMDIEQVSQLSALVQAQLEYHKQAVQILQQVTVRL
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 EERIRQASSQPRREYQPKPRMSLEFPTGDSTQPNGGLSHTGTPKPSGVQMDQPCCRALYD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS64 EERIRQASSQPRREYQPKPRMSLEFPTGDSTQPNGGLSHTGTPKPSGVQMDQPCCRALYD
250 260 270 280 290 300
310 320 330 340 350
pF1KB6 FEPENEGELGFKEGDIITLTNQIDENWYEGMLHGHSGFFPINYVEILVALPH
::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS64 FEPENEGELGFKEGDIITLTNQIDENWYEGMLHGHSGFFPINYVEILVALPH
310 320 330 340 350
>>CCDS10325.2 SH3GL3 gene_id:6457|Hs108|chr15 (347 aa)
initn: 1642 init1: 1212 opt: 1617 Z-score: 1188.6 bits: 228.4 E(32554): 7e-60
Smith-Waterman score: 1617; 68.1% identity (87.6% similar) in 354 aa overlap (1-352:1-347)
10 20 30 40 50 60
pF1KB6 MSVAGLKKQFHKATQKVSEKVGGAEGTKLDDDFKEMERKVDVTSRAVMEIMTKTIEYLQP
:::::::::::::.: :::..:::::::::.: .::::.:::...: ::..:: :::::
CCDS10 MSVAGLKKQFHKASQLFSEKISGAEGTKLDDEFLDMERKIDVTNKVVAEILSKTTEYLQP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 NPASRAKLSMINTMSKIRGQEKGPGYPQAEALLAEAMLKFGRELGDDCNFGPALGEVGEA
::: ::::.:.::.:::::: : ::::.:.::.. :::.:.:::.: .:: :: ::::.
CCDS10 NPAYRAKLGMLNTVSKIRGQVKTTGYPQTEGLLGDCMLKYGKELGEDSTFGNALIEVGES
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 MRELSEVKDSLDIEVKQNFIDPLQNLHDKDLREIQHHLKKLEGRRLDFDYKKKRQGKIPD
:. ..::::::::.:::.:::::: :.::::.:: ::::::::::::.:::::: :::::
CCDS10 MKLMAEVKDSLDINVKQTFIDPLQLLQDKDLKEIGHHLKKLEGRRLDYDYKKKRVGKIPD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 EELRQALEKFDESKEIAESSMFNLLEMDIEQVSQLSALVQAQLEYHKQAVQILQQVTVRL
::.:::.:::.::::.:: ::::.:: :.::::::.....: :.::.:...:::.. .:
CCDS10 EEVRQAVEKFEESKELAERSMFNFLENDVEQVSQLAVFIEAALDYHRQSTEILQELQSKL
190 200 210 220 230 240
250 260 270 280 290
pF1KB6 EERIRQASSQPRREYQPKPRMSLEFPTGDSTQPNGGLSHTGTPKPSG--VQMDQPCCRAL
. :: ::: :::::.:.: . :.. .:.: :.. : .: . :::::::.:
CCDS10 QMRISAASSVPRREYKPRP-------VKRSSSELNGVSTTSVVKTTGSNIPMDQPCCRGL
250 260 270 280 290
300 310 320 330 340 350
pF1KB6 YDFEPENEGELGFKEGDIITLTNQIDENWYEGMLHGHSGFFPINYVEILVALPH
:::::::.:::::::::::::::::::::::::.::.::::::::::..: ::.
CCDS10 YDFEPENQGELGFKEGDIITLTNQIDENWYEGMIHGESGFFPINYVEVIVPLPQ
300 310 320 330 340
>>CCDS73772.1 SH3GL3 gene_id:6457|Hs108|chr15 (355 aa)
initn: 1554 init1: 1124 opt: 1532 Z-score: 1127.1 bits: 217.1 E(32554): 1.9e-56
Smith-Waterman score: 1532; 67.1% identity (87.1% similar) in 340 aa overlap (15-352:23-355)
10 20 30 40 50
pF1KB6 MSVAGLKKQFHKATQKVSEKVGGAEGTKLDDDFKEMERKVDVTSRAVMEIMT
: :::..:::::::::.: .::::.:::...: ::..
CCDS73 MDGIFAGIICNQANRCLTWTSQQLFSEKISGAEGTKLDDEFLDMERKIDVTNKVVAEILS
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB6 KTIEYLQPNPASRAKLSMINTMSKIRGQEKGPGYPQAEALLAEAMLKFGRELGDDCNFGP
:: :::::::: ::::.:.::.:::::: : ::::.:.::.. :::.:.:::.: .::
CCDS73 KTTEYLQPNPAYRAKLGMLNTVSKIRGQVKTTGYPQTEGLLGDCMLKYGKELGEDSTFGN
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB6 ALGEVGEAMRELSEVKDSLDIEVKQNFIDPLQNLHDKDLREIQHHLKKLEGRRLDFDYKK
:: ::::.:. ..::::::::.:::.:::::: :.::::.:: ::::::::::::.::::
CCDS73 ALIEVGESMKLMAEVKDSLDINVKQTFIDPLQLLQDKDLKEIGHHLKKLEGRRLDYDYKK
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB6 KRQGKIPDEELRQALEKFDESKEIAESSMFNLLEMDIEQVSQLSALVQAQLEYHKQAVQI
:: :::::::.:::.:::.::::.:: ::::.:: :.::::::.....: :.::.:...:
CCDS73 KRVGKIPDEEVRQAVEKFEESKELAERSMFNFLENDVEQVSQLAVFIEAALDYHRQSTEI
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB6 LQQVTVRLEERIRQASSQPRREYQPKPRMSLEFPTGDSTQPNGGLSHTGTPKPSG--VQM
::.. .:. :: ::: :::::.:.: . :.. .:.: :.. : .: . :
CCDS73 LQELQSKLQMRISAASSVPRREYKPRP-------VKRSSSELNGVSTTSVVKTTGSNIPM
250 260 270 280 290
300 310 320 330 340 350
pF1KB6 DQPCCRALYDFEPENEGELGFKEGDIITLTNQIDENWYEGMLHGHSGFFPINYVEILVAL
::::::.::::::::.:::::::::::::::::::::::::.::.::::::::::..: :
CCDS73 DQPCCRGLYDFEPENQGELGFKEGDIITLTNQIDENWYEGMIHGESGFFPINYVEVIVPL
300 310 320 330 340 350
pF1KB6 PH
:.
CCDS73 PQ
>>CCDS32874.1 SH3GL1 gene_id:6455|Hs108|chr19 (368 aa)
initn: 1721 init1: 1349 opt: 1390 Z-score: 1024.4 bits: 198.1 E(32554): 9.8e-51
Smith-Waterman score: 1720; 71.1% identity (87.0% similar) in 370 aa overlap (1-352:1-368)
10 20 30 40 50 60
pF1KB6 MSVAGLKKQFHKATQKVSEKVGGAEGTKLDDDFKEMERKVDVTSRAVMEIMTKTIEYLQP
::::::::::.::.: :::::::::::::::::::::.::::::.:: :....:::::::
CCDS32 MSVAGLKKQFYKASQLVSEKVGGAEGTKLDDDFKEMEKKVDVTSKAVTEVLARTIEYLQP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 NPASRAKLSMINTMSKIRGQEKGPGYPQAEALLAEAMLKFGRELGDDCNFGPALGEVGEA
::::::::.:.::.:::::: :.:::::.:.::.: :.. :.::: . ::: :: ..::.
CCDS32 NPASRAKLTMLNTVSKIRGQVKNPGYPQSEGLLGECMIRHGKELGGESNFGDALLDAGES
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 MRELSEVKDSLDIEVKQNFIDPLQNLHDKDLREIQHHLKKLEGRRLDFDYKKKRQGKIPD
:..:.::::::::::::::::::::: .:::.::::::::::::::::::::::::::::
CCDS32 MKRLAEVKDSLDIEVKQNFIDPLQNLCEKDLKEIQHHLKKLEGRRLDFDYKKKRQGKIPD
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 EELRQALEKFDESKEIAESSMFNLLEMDIEQVSQLSALVQAQLEYHKQAVQILQQVTVRL
::::::::::.::::.::.:: :::: ::::::::::::.:::.::.::::::.... .:
CCDS32 EELRQALEKFEESKEVAETSMHNLLETDIEQVSQLSALVDAQLDYHRQAVQILDELAEKL
190 200 210 220 230 240
250 260 270 280
pF1KB6 EERIRQASSQPRREYQPKPRMSLEFPTGDSTQPNGGLSHTGTPK----------------
..:.:.:::.:.:::.:::: : :. : :::. : .::
CCDS32 KRRMREASSRPKREYKPKPREP--FDLGEPEQSNGGFPCTTAPKIAASSSFRSSDKPIRT
250 260 270 280 290
290 300 310 320 330 340
pF1KB6 PSGVQ--MDQPCCRALYDFEPENEGELGFKEGDIITLTNQIDENWYEGMLHGHSGFFPIN
:: . .::: :.:::::::::.:::::.:::.:::::::::::::::: :.:::::..
CCDS32 PSRSMPPLDQPSCKALYDFEPENDGELGFHEGDVITLTNQIDENWYEGMLDGQSGFFPLS
300 310 320 330 340 350
350
pF1KB6 YVEILVALPH
:::.:: ::.
CCDS32 YVEVLVPLPQ
360
>>CCDS56076.1 SH3GL1 gene_id:6455|Hs108|chr19 (320 aa)
initn: 1161 init1: 789 opt: 830 Z-score: 620.9 bits: 123.3 E(32554): 2.9e-28
Smith-Waterman score: 1395; 62.4% identity (75.4% similar) in 370 aa overlap (1-352:1-320)
10 20 30 40 50 60
pF1KB6 MSVAGLKKQFHKATQKVSEKVGGAEGTKLDDDFKEMERKVDVTSRAVMEIMTKTIEYLQP
::::::::::.::.: :::::::::::::::::::::.::::::.:: :....:::::::
CCDS56 MSVAGLKKQFYKASQLVSEKVGGAEGTKLDDDFKEMEKKVDVTSKAVTEVLARTIEYLQP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 NPASRAKLSMINTMSKIRGQEKGPGYPQAEALLAEAMLKFGRELGDDCNFGPALGEVGEA
:: : :: ..::.
CCDS56 NP------------------------------------------------GDALLDAGES
70
130 140 150 160 170 180
pF1KB6 MRELSEVKDSLDIEVKQNFIDPLQNLHDKDLREIQHHLKKLEGRRLDFDYKKKRQGKIPD
:..:.::::::::::::::::::::: .:::.::::::::::::::::::::::::::::
CCDS56 MKRLAEVKDSLDIEVKQNFIDPLQNLCEKDLKEIQHHLKKLEGRRLDFDYKKKRQGKIPD
80 90 100 110 120 130
190 200 210 220 230 240
pF1KB6 EELRQALEKFDESKEIAESSMFNLLEMDIEQVSQLSALVQAQLEYHKQAVQILQQVTVRL
::::::::::.::::.::.:: :::: ::::::::::::.:::.::.::::::.... .:
CCDS56 EELRQALEKFEESKEVAETSMHNLLETDIEQVSQLSALVDAQLDYHRQAVQILDELAEKL
140 150 160 170 180 190
250 260 270 280
pF1KB6 EERIRQASSQPRREYQPKPRMSLEFPTGDSTQPNGGLSHTGTPK----------------
..:.:.:::.:.:::.:::: : :. : :::. : .::
CCDS56 KRRMREASSRPKREYKPKPREP--FDLGEPEQSNGGFPCTTAPKIAASSSFRSSDKPIRT
200 210 220 230 240 250
290 300 310 320 330 340
pF1KB6 PSGVQ--MDQPCCRALYDFEPENEGELGFKEGDIITLTNQIDENWYEGMLHGHSGFFPIN
:: . .::: :.:::::::::.:::::.:::.:::::::::::::::: :.:::::..
CCDS56 PSRSMPPLDQPSCKALYDFEPENDGELGFHEGDVITLTNQIDENWYEGMLDGQSGFFPLS
260 270 280 290 300 310
350
pF1KB6 YVEILVALPH
:::.:: ::.
CCDS56 YVEVLVPLPQ
320
>>CCDS59335.1 SH3GL1 gene_id:6455|Hs108|chr19 (304 aa)
initn: 997 init1: 625 opt: 666 Z-score: 502.9 bits: 101.3 E(32554): 1.1e-21
Smith-Waterman score: 1290; 59.5% identity (71.6% similar) in 370 aa overlap (1-352:1-304)
10 20 30 40 50 60
pF1KB6 MSVAGLKKQFHKATQKVSEKVGGAEGTKLDDDFKEMERKVDVTSRAVMEIMTKTIEYLQP
::::::::::.::.: :::::::::::::::::::::.::::::.:: :....:::::::
CCDS59 MSVAGLKKQFYKASQLVSEKVGGAEGTKLDDDFKEMEKKVDVTSKAVTEVLARTIEYLQP
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 NPASRAKLSMINTMSKIRGQEKGPGYPQAEALLAEAMLKFGRELGDDCNFGPALGEVGEA
::::::::.:.::.::::::
CCDS59 NPASRAKLTMLNTVSKIRGQ----------------------------------------
70 80
130 140 150 160 170 180
pF1KB6 MRELSEVKDSLDIEVKQNFIDPLQNLHDKDLREIQHHLKKLEGRRLDFDYKKKRQGKIPD
:: .:::.::::::::::::::::::::::::::::
CCDS59 ------------------------NLCEKDLKEIQHHLKKLEGRRLDFDYKKKRQGKIPD
90 100 110
190 200 210 220 230 240
pF1KB6 EELRQALEKFDESKEIAESSMFNLLEMDIEQVSQLSALVQAQLEYHKQAVQILQQVTVRL
::::::::::.::::.::.:: :::: ::::::::::::.:::.::.::::::.... .:
CCDS59 EELRQALEKFEESKEVAETSMHNLLETDIEQVSQLSALVDAQLDYHRQAVQILDELAEKL
120 130 140 150 160 170
250 260 270 280
pF1KB6 EERIRQASSQPRREYQPKPRMSLEFPTGDSTQPNGGLSHTGTPK----------------
..:.:.:::.:.:::.:::: : :. : :::. : .::
CCDS59 KRRMREASSRPKREYKPKPREP--FDLGEPEQSNGGFPCTTAPKIAASSSFRSSDKPIRT
180 190 200 210 220 230
290 300 310 320 330 340
pF1KB6 PSGVQ--MDQPCCRALYDFEPENEGELGFKEGDIITLTNQIDENWYEGMLHGHSGFFPIN
:: . .::: :.:::::::::.:::::.:::.:::::::::::::::: :.:::::..
CCDS59 PSRSMPPLDQPSCKALYDFEPENDGELGFHEGDVITLTNQIDENWYEGMLDGQSGFFPLS
240 250 260 270 280 290
350
pF1KB6 YVEILVALPH
:::.:: ::.
CCDS59 YVEVLVPLPQ
300
352 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 20:56:01 2016 done: Fri Nov 4 20:56:01 2016
Total Scan time: 2.430 Total Display time: 0.000
Function used was FASTA [36.3.4 Apr, 2011]