FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6464, 352 aa 1>>>pF1KB6464 352 - 352 aa - 352 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.1711+/-0.000761; mu= 17.2597+/- 0.046 mean_var=70.6783+/-13.622, 0's: 0 Z-trim(109.0): 45 B-trim: 0 in 0/51 Lambda= 0.152557 statistics sampled from 10531 (10576) to 10531 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.699), E-opt: 0.2 (0.325), width: 16 Scan time: 2.220 The best scores are: opt bits E(32554) CCDS6800.1 AMBP gene_id:259|Hs108|chr9 ( 352) 2437 545.3 2.9e-155 CCDS82159.1 WFIKKN2 gene_id:124857|Hs108|chr17 ( 483) 345 84.9 1.5e-16 CCDS11575.1 WFIKKN2 gene_id:124857|Hs108|chr17 ( 576) 345 85.0 1.7e-16 CCDS10414.1 WFIKKN1 gene_id:117166|Hs108|chr16 ( 548) 290 72.9 7.3e-13 CCDS7019.1 PTGDS gene_id:5730|Hs108|chr9 ( 190) 261 66.2 2.6e-11 >>CCDS6800.1 AMBP gene_id:259|Hs108|chr9 (352 aa) initn: 2437 init1: 2437 opt: 2437 Z-score: 2900.9 bits: 545.3 E(32554): 2.9e-155 Smith-Waterman score: 2437; 100.0% identity (100.0% similar) in 352 aa overlap (1-352:1-352) 10 20 30 40 50 60 pF1KB6 MRSLGALLLLLSACLAVSAGPVPTPPDNIQVQENFNISRIYGKWYNLAIGSTCPWLKKIM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS68 MRSLGALLLLLSACLAVSAGPVPTPPDNIQVQENFNISRIYGKWYNLAIGSTCPWLKKIM 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 DRMTVSTLVLGEGATEAEISMTSTRWRKGVCEETSGAYEKTDTDGKFLYHKSKWNITMES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS68 DRMTVSTLVLGEGATEAEISMTSTRWRKGVCEETSGAYEKTDTDGKFLYHKSKWNITMES 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 YVVHTNYDEYAIFLTKKFSRHHGPTITAKLYGRAPQLRETLLQDFRVVAQGVGIPEDSIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS68 YVVHTNYDEYAIFLTKKFSRHHGPTITAKLYGRAPQLRETLLQDFRVVAQGVGIPEDSIF 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 TMADRGECVPGEQEPEPILIPRVRRAVLPQEEEGSGGGQLVTEVTKKEDSCQLGYSAGPC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS68 TMADRGECVPGEQEPEPILIPRVRRAVLPQEEEGSGGGQLVTEVTKKEDSCQLGYSAGPC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 MGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTCRTVAACNLPIVRGPCRAFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS68 MGMTSRYFYNGTSMACETFQYGGCMGNGNNFVTEKECLQTCRTVAACNLPIVRGPCRAFI 250 260 270 280 290 300 310 320 330 340 350 pF1KB6 QLWAFDAVKGKCVLFPYGGCQGNGNKFYSEKECREYCGVPGDGDEELLRFSN :::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS68 QLWAFDAVKGKCVLFPYGGCQGNGNKFYSEKECREYCGVPGDGDEELLRFSN 310 320 330 340 350 >>CCDS82159.1 WFIKKN2 gene_id:124857|Hs108|chr17 (483 aa) initn: 401 init1: 241 opt: 345 Z-score: 410.6 bits: 84.9 E(32554): 1.5e-16 Smith-Waterman score: 345; 31.5% identity (59.6% similar) in 178 aa overlap (166-340:178-346) 140 150 160 170 180 190 pF1KB6 KKFSRHHGPTITAKLYGRAPQLRETLLQDFRVVAQGVGIPEDSIFTMADRGECVPGEQEP ..: .. . . .:.: . :. : : . CCDS82 ITWEKQLEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQLQDAGIYTCTARN--VAGVLRA 150 160 170 180 190 200 200 210 220 230 240 250 pF1KB6 E-PILIPRVRRAVLPQEEEGSGGGQLVTEVTKKEDSCQLGYSAGPCMGMTSRYFYNGTSM . :. . : ..:. .: .: . ..: : :: . : .:. ... . CCDS82 DFPLSVVRGHQAAATSESSPNGTAFPAAECLKPPDSED-------CGEEQTRWHFDAQAN 210 220 230 240 250 260 270 280 290 300 310 pF1KB6 ACETFQYGGCMGNGNNFVTEKECLQTCRT--VAACNLPIVRGPCRAFIQLWAFDAVKGKC : :: .: : : :.: : . :. .: . .:::.:: ..:::.:. ::... :.: CCDS82 NCLTFTFGHCHRNLNHFETYEACMLACMSGPLAACSLPALQGPCKAYAPRWAYNSQTGQC 260 270 280 290 300 310 320 330 340 350 pF1KB6 VLFPYGGCQGNGNKFYSEKECREYCGVPGDGDEELLRFSN : ::::.::::.: :.. :.: : : CCDS82 QSFVYGGCEGNGNNFESREACEESCPFPRGNQRCRACKPRQKLVTSFCRSDFVILGRVSE 320 330 340 350 360 370 >>CCDS11575.1 WFIKKN2 gene_id:124857|Hs108|chr17 (576 aa) initn: 426 init1: 241 opt: 345 Z-score: 409.5 bits: 85.0 E(32554): 1.7e-16 Smith-Waterman score: 345; 31.5% identity (59.6% similar) in 178 aa overlap (166-340:271-439) 140 150 160 170 180 190 pF1KB6 KKFSRHHGPTITAKLYGRAPQLRETLLQDFRVVAQGVGIPEDSIFTMADRGECVPGEQEP ..: .. . . .:.: . :. : : . CCDS11 ITWEKQLEDRENVVMRPNHVRGNVVVTNIAQLVIYNAQLQDAGIYTCTARN--VAGVLRA 250 260 270 280 290 200 210 220 230 240 250 pF1KB6 E-PILIPRVRRAVLPQEEEGSGGGQLVTEVTKKEDSCQLGYSAGPCMGMTSRYFYNGTSM . :. . : ..:. .: .: . ..: : :: . : .:. ... . CCDS11 DFPLSVVRGHQAAATSESSPNGTAFPAAECLKPPDSED-------CGEEQTRWHFDAQAN 300 310 320 330 340 350 260 270 280 290 300 310 pF1KB6 ACETFQYGGCMGNGNNFVTEKECLQTCRT--VAACNLPIVRGPCRAFIQLWAFDAVKGKC : :: .: : : :.: : . :. .: . .:::.:: ..:::.:. ::... :.: CCDS11 NCLTFTFGHCHRNLNHFETYEACMLACMSGPLAACSLPALQGPCKAYAPRWAYNSQTGQC 360 370 380 390 400 410 320 330 340 350 pF1KB6 VLFPYGGCQGNGNKFYSEKECREYCGVPGDGDEELLRFSN : ::::.::::.: :.. :.: : : CCDS11 QSFVYGGCEGNGNNFESREACEESCPFPRGNQRCRACKPRQKLVTSFCRSDFVILGRVSE 420 430 440 450 460 470 >>CCDS10414.1 WFIKKN1 gene_id:117166|Hs108|chr16 (548 aa) initn: 346 init1: 220 opt: 290 Z-score: 344.4 bits: 72.9 E(32554): 7.3e-13 Smith-Waterman score: 290; 40.2% identity (60.7% similar) in 107 aa overlap (240-340:306-412) 210 220 230 240 250 260 pF1KB6 QEEEGSGGGQLVTEVTKKEDSCQLGYSAGPCMGMTSRYF----YNGTSMACETFQYGGCM : : :: .. :. .: :: :: CCDS10 FPLSVVQREPARDAAPSIPAPAECLPDVQACTGPTSPHLVLWHYDPQRGGCMTFPARGCD 280 290 300 310 320 330 270 280 290 300 310 320 pF1KB6 GNGNNFVTEKECLQTCRTVA--ACNLPIVRGPCRAFIQLWAFDAVKGKCVLFPYGGCQGN : . .: : . : :.: :: :: :.::::.. ::.. . .: : ::::.:: CCDS10 GAARGFETYEACQQACARGPGDACVLPAVQGPCRGWEPRWAYSPLLQQCHPFVYGGCEGN 340 350 360 370 380 390 330 340 350 pF1KB6 GNKFYSEKECREYCGVPGDGDEELLRFSN ::.:.:.. :.. : :: CCDS10 GNNFHSRESCEDACPVPRTPPCRACRLRSKLALSLCRSDFAIVGRLTEVLEEPEAAGGIA 400 410 420 430 440 450 >>CCDS7019.1 PTGDS gene_id:5730|Hs108|chr9 (190 aa) initn: 244 init1: 175 opt: 261 Z-score: 316.4 bits: 66.2 E(32554): 2.6e-11 Smith-Waterman score: 261; 27.0% identity (61.8% similar) in 178 aa overlap (13-189:12-187) 10 20 30 40 50 60 pF1KB6 MRSLGALLLLLSACLAVSAGPVPTPPDNIQVQENFNISRIYGKWYNLAIGSTCPWLKKIM : :.: . .: ...:: ::. ... :.:.. ...:. ::.. CCDS70 MATHHTLWMGLALLGVLGDLQAAPEAQVSVQPNFQQDKFLGRWFSAGLASNSSWLREKK 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 DRMTVSTLVLGEGATEAEISMTSTRWRKGVCEETSGAYEKTDTDGKFLYHKSKWNITMES ... :.. ::.. ...::: ::. :: . . . . :.. :.. .:. :. CCDS70 AALSMCKSVVAP-ATDGGLNLTSTFLRKNQCETRTMLLQPAGSLGSYSYRSPHWGSTYSV 60 70 80 90 100 110 130 140 150 160 170 pF1KB6 YVVHTNYDEYAIFLTKKFSRHHGPTIT-AKLYGRAPQLRETLLQDFRVVAQGVGIPEDSI ::.:.::.::.. .. :. : . : ::.:. : : . : . .. :. ::.: CCDS70 SVVETDYDQYALLYSQG-SKGPGEDFRMATLYSRTQTPRAELKEKFTAFCKAQGFTEDTI 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB6 FTMADRGECVPGEQEPEPILIPRVRRAVLPQEEEGSGGGQLVTEVTKKEDSCQLGYSAGP . . .:. CCDS70 VFLPQTDKCMTEQ 180 190 352 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 20:56:34 2016 done: Fri Nov 4 20:56:34 2016 Total Scan time: 2.220 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]