FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6466, 352 aa 1>>>pF1KB6466 352 - 352 aa - 352 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.9934+/-0.000317; mu= 10.6862+/- 0.020 mean_var=135.5571+/-27.700, 0's: 0 Z-trim(120.1): 169 B-trim: 1238 in 1/56 Lambda= 0.110157 statistics sampled from 34790 (34963) to 34790 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.744), E-opt: 0.2 (0.41), width: 16 Scan time: 7.480 The best scores are: opt bits E(85289) NP_065115 (OMIM: 607240) N-lysine methyltransferas ( 352) 2348 384.0 2.7e-106 NP_001311433 (OMIM: 607240) N-lysine methyltransfe ( 322) 2107 345.6 8.6e-95 XP_006719457 (OMIM: 607240) PREDICTED: N-lysine me ( 315) 2060 338.2 1.5e-92 XP_011536635 (OMIM: 607240) PREDICTED: N-lysine me ( 295) 1977 325.0 1.3e-88 NP_001311434 (OMIM: 607240) N-lysine methyltransfe ( 295) 1977 325.0 1.3e-88 NP_001311435 (OMIM: 607240) N-lysine methyltransfe ( 244) 1627 269.3 6.4e-72 XP_006718902 (OMIM: 159555,605130) PREDICTED: hist (3133) 258 52.5 1.4e-05 XP_011541135 (OMIM: 159555,605130) PREDICTED: hist (3166) 258 52.6 1.4e-05 NP_005924 (OMIM: 159555,605130) histone-lysine N-m (3969) 258 52.6 1.7e-05 NP_001184033 (OMIM: 159555,605130) histone-lysine (3972) 258 52.6 1.7e-05 XP_011541133 (OMIM: 159555,605130) PREDICTED: hist (4002) 258 52.6 1.7e-05 XP_011541132 (OMIM: 159555,605130) PREDICTED: hist (4004) 258 52.6 1.7e-05 XP_011541131 (OMIM: 159555,605130) PREDICTED: hist (4005) 258 52.6 1.7e-05 XP_016879841 (OMIM: 601674) PREDICTED: histone-lys ( 410) 236 48.4 3.4e-05 XP_016883035 (OMIM: 606834) PREDICTED: histone-lys (1703) 243 50.0 4.7e-05 XP_016879840 (OMIM: 601674) PREDICTED: histone-lys ( 637) 236 48.5 4.7e-05 XP_016879839 (OMIM: 601674) PREDICTED: histone-lys ( 668) 236 48.5 4.9e-05 NP_001308011 (OMIM: 601674) histone-lysine N-methy ( 707) 236 48.6 5.1e-05 XP_005257202 (OMIM: 601674) PREDICTED: histone-lys ( 713) 236 48.6 5.1e-05 NP_001308010 (OMIM: 601674) histone-lysine N-methy ( 738) 236 48.6 5.3e-05 XP_011522819 (OMIM: 601674) PREDICTED: histone-lys ( 744) 236 48.6 5.3e-05 NP_001982 (OMIM: 601674) histone-lysine N-methyltr ( 747) 236 48.6 5.3e-05 NP_001308008 (OMIM: 601674) histone-lysine N-methy ( 753) 236 48.6 5.4e-05 XP_011525863 (OMIM: 606834) PREDICTED: histone-lys (2527) 243 50.1 6.3e-05 XP_016883034 (OMIM: 606834) PREDICTED: histone-lys (2527) 243 50.1 6.3e-05 XP_016883033 (OMIM: 606834) PREDICTED: histone-lys (2685) 243 50.1 6.6e-05 NP_055542 (OMIM: 606834) histone-lysine N-methyltr (2715) 243 50.1 6.7e-05 XP_011517964 (OMIM: 606503) PREDICTED: histone-lys ( 350) 220 45.8 0.00017 XP_006717566 (OMIM: 606503) PREDICTED: histone-lys ( 350) 220 45.8 0.00017 NP_078946 (OMIM: 606503) histone-lysine N-methyltr ( 350) 220 45.8 0.00017 XP_016872126 (OMIM: 606503) PREDICTED: histone-lys ( 350) 220 45.8 0.00017 NP_001180354 (OMIM: 606503) histone-lysine N-methy ( 350) 220 45.8 0.00017 NP_001180353 (OMIM: 606503) histone-lysine N-methy ( 410) 220 45.8 0.0002 NP_003164 (OMIM: 300254) histone-lysine N-methyltr ( 412) 217 45.4 0.00027 NP_001269095 (OMIM: 300254) histone-lysine N-methy ( 423) 217 45.4 0.00028 XP_016867310 (OMIM: 277590,601573) PREDICTED: hist ( 637) 218 45.7 0.00034 XP_011514200 (OMIM: 277590,601573) PREDICTED: hist ( 642) 218 45.7 0.00034 XP_011514199 (OMIM: 277590,601573) PREDICTED: hist ( 642) 218 45.7 0.00034 XP_011514198 (OMIM: 277590,601573) PREDICTED: hist ( 673) 218 45.7 0.00036 NP_001190178 (OMIM: 277590,601573) histone-lysine ( 695) 218 45.7 0.00037 XP_005250021 (OMIM: 277590,601573) PREDICTED: hist ( 703) 218 45.7 0.00037 XP_016867309 (OMIM: 277590,601573) PREDICTED: hist ( 703) 218 45.7 0.00037 NP_694543 (OMIM: 277590,601573) histone-lysine N-m ( 707) 218 45.7 0.00037 XP_011514197 (OMIM: 277590,601573) PREDICTED: hist ( 711) 218 45.7 0.00037 XP_016867308 (OMIM: 277590,601573) PREDICTED: hist ( 712) 218 45.7 0.00037 XP_011514196 (OMIM: 277590,601573) PREDICTED: hist ( 712) 218 45.7 0.00037 XP_011514195 (OMIM: 277590,601573) PREDICTED: hist ( 715) 218 45.7 0.00037 XP_011514194 (OMIM: 277590,601573) PREDICTED: hist ( 717) 218 45.7 0.00038 XP_011514193 (OMIM: 277590,601573) PREDICTED: hist ( 718) 218 45.7 0.00038 XP_011514192 (OMIM: 277590,601573) PREDICTED: hist ( 720) 218 45.7 0.00038 >>NP_065115 (OMIM: 607240) N-lysine methyltransferase KM (352 aa) initn: 2348 init1: 2348 opt: 2348 Z-score: 2029.2 bits: 384.0 E(85289): 2.7e-106 Smith-Waterman score: 2348; 100.0% identity (100.0% similar) in 352 aa overlap (1-352:1-352) 10 20 30 40 50 60 pF1KB6 MARGRKMSKPRAVEAAAAAAAVAATAPGPEMVERRGPGRPRTDGENVFTGQSKIYSYMSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 MARGRKMSKPRAVEAAAAAAAVAATAPGPEMVERRGPGRPRTDGENVFTGQSKIYSYMSP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 NKCSGMRFPLQEENSVTHHEVKCQGKPLAGIYRKREEKRNAGNAVRSAMKSEEQKIKDAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 NKCSGMRFPLQEENSVTHHEVKCQGKPLAGIYRKREEKRNAGNAVRSAMKSEEQKIKDAR 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 KGPLVPFPNQKSEAAEPPKTPPSSCDSTNAAIAKQALKKPIKGKQAPRKKAQGKTQQNRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 KGPLVPFPNQKSEAAEPPKTPPSSCDSTNAAIAKQALKKPIKGKQAPRKKAQGKTQQNRK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 LTDFYPVRRSSRKSKAELQSEERKRIDELIESGKEEGMKIDLIDGKGRGVIATKQFSRGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 LTDFYPVRRSSRKSKAELQSEERKRIDELIESGKEEGMKIDLIDGKGRGVIATKQFSRGD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 FVVEYHGDLIEITDAKKREALYAQDPSTGCYMYYFQYLSKTYCVDATRETNRLGRLINHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 FVVEYHGDLIEITDAKKREALYAQDPSTGCYMYYFQYLSKTYCVDATRETNRLGRLINHS 250 260 270 280 290 300 310 320 330 340 350 pF1KB6 KCGNCQTKLHDIDGVPHLILIASRDIAAGEELLYDYGDRSKASIEAHPWLKH :::::::::::::::::::::::::::::::::::::::::::::::::::: NP_065 KCGNCQTKLHDIDGVPHLILIASRDIAAGEELLYDYGDRSKASIEAHPWLKH 310 320 330 340 350 >>NP_001311433 (OMIM: 607240) N-lysine methyltransferase (322 aa) initn: 2101 init1: 2101 opt: 2107 Z-score: 1822.8 bits: 345.6 E(85289): 8.6e-95 Smith-Waterman score: 2107; 97.8% identity (99.1% similar) in 322 aa overlap (31-352:1-322) 10 20 30 40 50 60 pF1KB6 MARGRKMSKPRAVEAAAAAAAVAATAPGPEMVERRGPGRPRTDGENVFTGQSKIYSYMSP :.. : ..::::::::::::::::::::: NP_001 MARGRKMSKPRTDGENVFTGQSKIYSYMSP 10 20 30 70 80 90 100 110 120 pF1KB6 NKCSGMRFPLQEENSVTHHEVKCQGKPLAGIYRKREEKRNAGNAVRSAMKSEEQKIKDAR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NKCSGMRFPLQEENSVTHHEVKCQGKPLAGIYRKREEKRNAGNAVRSAMKSEEQKIKDAR 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB6 KGPLVPFPNQKSEAAEPPKTPPSSCDSTNAAIAKQALKKPIKGKQAPRKKAQGKTQQNRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KGPLVPFPNQKSEAAEPPKTPPSSCDSTNAAIAKQALKKPIKGKQAPRKKAQGKTQQNRK 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB6 LTDFYPVRRSSRKSKAELQSEERKRIDELIESGKEEGMKIDLIDGKGRGVIATKQFSRGD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LTDFYPVRRSSRKSKAELQSEERKRIDELIESGKEEGMKIDLIDGKGRGVIATKQFSRGD 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB6 FVVEYHGDLIEITDAKKREALYAQDPSTGCYMYYFQYLSKTYCVDATRETNRLGRLINHS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FVVEYHGDLIEITDAKKREALYAQDPSTGCYMYYFQYLSKTYCVDATRETNRLGRLINHS 220 230 240 250 260 270 310 320 330 340 350 pF1KB6 KCGNCQTKLHDIDGVPHLILIASRDIAAGEELLYDYGDRSKASIEAHPWLKH :::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KCGNCQTKLHDIDGVPHLILIASRDIAAGEELLYDYGDRSKASIEAHPWLKH 280 290 300 310 320 >>XP_006719457 (OMIM: 607240) PREDICTED: N-lysine methyl (315 aa) initn: 2060 init1: 2060 opt: 2060 Z-score: 1782.5 bits: 338.2 E(85289): 1.5e-92 Smith-Waterman score: 2060; 100.0% identity (100.0% similar) in 308 aa overlap (45-352:8-315) 20 30 40 50 60 70 pF1KB6 AAAAAAAVAATAPGPEMVERRGPGRPRTDGENVFTGQSKIYSYMSPNKCSGMRFPLQEEN :::::::::::::::::::::::::::::: XP_006 MGLAGLQENVFTGQSKIYSYMSPNKCSGMRFPLQEEN 10 20 30 80 90 100 110 120 130 pF1KB6 SVTHHEVKCQGKPLAGIYRKREEKRNAGNAVRSAMKSEEQKIKDARKGPLVPFPNQKSEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SVTHHEVKCQGKPLAGIYRKREEKRNAGNAVRSAMKSEEQKIKDARKGPLVPFPNQKSEA 40 50 60 70 80 90 140 150 160 170 180 190 pF1KB6 AEPPKTPPSSCDSTNAAIAKQALKKPIKGKQAPRKKAQGKTQQNRKLTDFYPVRRSSRKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AEPPKTPPSSCDSTNAAIAKQALKKPIKGKQAPRKKAQGKTQQNRKLTDFYPVRRSSRKS 100 110 120 130 140 150 200 210 220 230 240 250 pF1KB6 KAELQSEERKRIDELIESGKEEGMKIDLIDGKGRGVIATKQFSRGDFVVEYHGDLIEITD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 KAELQSEERKRIDELIESGKEEGMKIDLIDGKGRGVIATKQFSRGDFVVEYHGDLIEITD 160 170 180 190 200 210 260 270 280 290 300 310 pF1KB6 AKKREALYAQDPSTGCYMYYFQYLSKTYCVDATRETNRLGRLINHSKCGNCQTKLHDIDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 AKKREALYAQDPSTGCYMYYFQYLSKTYCVDATRETNRLGRLINHSKCGNCQTKLHDIDG 220 230 240 250 260 270 320 330 340 350 pF1KB6 VPHLILIASRDIAAGEELLYDYGDRSKASIEAHPWLKH :::::::::::::::::::::::::::::::::::::: XP_006 VPHLILIASRDIAAGEELLYDYGDRSKASIEAHPWLKH 280 290 300 310 >>XP_011536635 (OMIM: 607240) PREDICTED: N-lysine methyl (295 aa) initn: 1977 init1: 1977 opt: 1977 Z-score: 1711.6 bits: 325.0 E(85289): 1.3e-88 Smith-Waterman score: 1977; 100.0% identity (100.0% similar) in 295 aa overlap (58-352:1-295) 30 40 50 60 70 80 pF1KB6 GPEMVERRGPGRPRTDGENVFTGQSKIYSYMSPNKCSGMRFPLQEENSVTHHEVKCQGKP :::::::::::::::::::::::::::::: XP_011 MSPNKCSGMRFPLQEENSVTHHEVKCQGKP 10 20 30 90 100 110 120 130 140 pF1KB6 LAGIYRKREEKRNAGNAVRSAMKSEEQKIKDARKGPLVPFPNQKSEAAEPPKTPPSSCDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LAGIYRKREEKRNAGNAVRSAMKSEEQKIKDARKGPLVPFPNQKSEAAEPPKTPPSSCDS 40 50 60 70 80 90 150 160 170 180 190 200 pF1KB6 TNAAIAKQALKKPIKGKQAPRKKAQGKTQQNRKLTDFYPVRRSSRKSKAELQSEERKRID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TNAAIAKQALKKPIKGKQAPRKKAQGKTQQNRKLTDFYPVRRSSRKSKAELQSEERKRID 100 110 120 130 140 150 210 220 230 240 250 260 pF1KB6 ELIESGKEEGMKIDLIDGKGRGVIATKQFSRGDFVVEYHGDLIEITDAKKREALYAQDPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ELIESGKEEGMKIDLIDGKGRGVIATKQFSRGDFVVEYHGDLIEITDAKKREALYAQDPS 160 170 180 190 200 210 270 280 290 300 310 320 pF1KB6 TGCYMYYFQYLSKTYCVDATRETNRLGRLINHSKCGNCQTKLHDIDGVPHLILIASRDIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TGCYMYYFQYLSKTYCVDATRETNRLGRLINHSKCGNCQTKLHDIDGVPHLILIASRDIA 220 230 240 250 260 270 330 340 350 pF1KB6 AGEELLYDYGDRSKASIEAHPWLKH ::::::::::::::::::::::::: XP_011 AGEELLYDYGDRSKASIEAHPWLKH 280 290 >>NP_001311434 (OMIM: 607240) N-lysine methyltransferase (295 aa) initn: 1977 init1: 1977 opt: 1977 Z-score: 1711.6 bits: 325.0 E(85289): 1.3e-88 Smith-Waterman score: 1977; 100.0% identity (100.0% similar) in 295 aa overlap (58-352:1-295) 30 40 50 60 70 80 pF1KB6 GPEMVERRGPGRPRTDGENVFTGQSKIYSYMSPNKCSGMRFPLQEENSVTHHEVKCQGKP :::::::::::::::::::::::::::::: NP_001 MSPNKCSGMRFPLQEENSVTHHEVKCQGKP 10 20 30 90 100 110 120 130 140 pF1KB6 LAGIYRKREEKRNAGNAVRSAMKSEEQKIKDARKGPLVPFPNQKSEAAEPPKTPPSSCDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LAGIYRKREEKRNAGNAVRSAMKSEEQKIKDARKGPLVPFPNQKSEAAEPPKTPPSSCDS 40 50 60 70 80 90 150 160 170 180 190 200 pF1KB6 TNAAIAKQALKKPIKGKQAPRKKAQGKTQQNRKLTDFYPVRRSSRKSKAELQSEERKRID :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TNAAIAKQALKKPIKGKQAPRKKAQGKTQQNRKLTDFYPVRRSSRKSKAELQSEERKRID 100 110 120 130 140 150 210 220 230 240 250 260 pF1KB6 ELIESGKEEGMKIDLIDGKGRGVIATKQFSRGDFVVEYHGDLIEITDAKKREALYAQDPS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ELIESGKEEGMKIDLIDGKGRGVIATKQFSRGDFVVEYHGDLIEITDAKKREALYAQDPS 160 170 180 190 200 210 270 280 290 300 310 320 pF1KB6 TGCYMYYFQYLSKTYCVDATRETNRLGRLINHSKCGNCQTKLHDIDGVPHLILIASRDIA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TGCYMYYFQYLSKTYCVDATRETNRLGRLINHSKCGNCQTKLHDIDGVPHLILIASRDIA 220 230 240 250 260 270 330 340 350 pF1KB6 AGEELLYDYGDRSKASIEAHPWLKH ::::::::::::::::::::::::: NP_001 AGEELLYDYGDRSKASIEAHPWLKH 280 290 >>NP_001311435 (OMIM: 607240) N-lysine methyltransferase (244 aa) initn: 1627 init1: 1627 opt: 1627 Z-score: 1412.2 bits: 269.3 E(85289): 6.4e-72 Smith-Waterman score: 1627; 100.0% identity (100.0% similar) in 244 aa overlap (109-352:1-244) 80 90 100 110 120 130 pF1KB6 HEVKCQGKPLAGIYRKREEKRNAGNAVRSAMKSEEQKIKDARKGPLVPFPNQKSEAAEPP :::::::::::::::::::::::::::::: NP_001 MKSEEQKIKDARKGPLVPFPNQKSEAAEPP 10 20 30 140 150 160 170 180 190 pF1KB6 KTPPSSCDSTNAAIAKQALKKPIKGKQAPRKKAQGKTQQNRKLTDFYPVRRSSRKSKAEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KTPPSSCDSTNAAIAKQALKKPIKGKQAPRKKAQGKTQQNRKLTDFYPVRRSSRKSKAEL 40 50 60 70 80 90 200 210 220 230 240 250 pF1KB6 QSEERKRIDELIESGKEEGMKIDLIDGKGRGVIATKQFSRGDFVVEYHGDLIEITDAKKR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QSEERKRIDELIESGKEEGMKIDLIDGKGRGVIATKQFSRGDFVVEYHGDLIEITDAKKR 100 110 120 130 140 150 260 270 280 290 300 310 pF1KB6 EALYAQDPSTGCYMYYFQYLSKTYCVDATRETNRLGRLINHSKCGNCQTKLHDIDGVPHL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EALYAQDPSTGCYMYYFQYLSKTYCVDATRETNRLGRLINHSKCGNCQTKLHDIDGVPHL 160 170 180 190 200 210 320 330 340 350 pF1KB6 ILIASRDIAAGEELLYDYGDRSKASIEAHPWLKH :::::::::::::::::::::::::::::::::: NP_001 ILIASRDIAAGEELLYDYGDRSKASIEAHPWLKH 220 230 240 >>XP_006718902 (OMIM: 159555,605130) PREDICTED: histone- (3133 aa) initn: 295 init1: 143 opt: 258 Z-score: 221.0 bits: 52.5 E(85289): 1.4e-05 Smith-Waterman score: 278; 29.3% identity (60.6% similar) in 208 aa overlap (129-336:2912-3108) 100 110 120 130 140 150 pF1KB6 RNAGNAVRSAMKSEEQKIKDARKGPLVPFPNQKSEAAEPPKTPPSSCDSTNAAIAKQALK .. :: ::: .: .: . .. . :.:. XP_006 RMLGILHDAVVFLIEQLSGAKHCRNYKFRFHKPEEANEPPLNPHGSARA-EVHLRKSAFD 2890 2900 2910 2920 2930 2940 160 170 180 190 200 210 pF1KB6 KPIKGKQAPRKKAQGKTQQNRKLTDFYPVRRSSRKSKAELQSEERKRIDELIESGKEEGM . . : ... . . : . . .. . : .. .: : : .: ...:: .. XP_006 --MFNFLASKHRQPPEYNPNDEEEEEVQLKSARRATSMDLPMPMRFR--HLKKTSKE-AV 2950 2960 2970 2980 2990 220 230 240 250 260 270 pF1KB6 KIDLIDGKGRGVIATKQFSRGDFVVEYHGDLIEITDAKKREALYAQDPSTGCYMYYFQYL . .:::.. .... :..:.:: :..:. .. ::: : .. . ::::. . XP_006 GVYRSPIHGRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYY-DSKGIGCYMFR---I 3000 3010 3020 3030 3040 3050 280 290 300 310 320 330 pF1KB6 SKTYCVDATRETNRLGRLINHSKCGNCQTKLHDIDGVPHLILIASRDIAAGEELLYDYGD . . :::: . : .:.:::: :: ... .::: :....: : : :::: ::: XP_006 DDSEVVDATMHGNA-ARFINHSCEPNCYSRVINIDGQKHIVIFAMRKIYRGEELTYDYKF 3060 3070 3080 3090 3100 3110 340 350 pF1KB6 RSKASIEAHPWLKH XP_006 PIEDASNKLPCNCGAKKCRKFLN 3120 3130 >>XP_011541135 (OMIM: 159555,605130) PREDICTED: histone- (3166 aa) initn: 295 init1: 143 opt: 258 Z-score: 221.0 bits: 52.6 E(85289): 1.4e-05 Smith-Waterman score: 278; 29.3% identity (60.6% similar) in 208 aa overlap (129-336:2945-3141) 100 110 120 130 140 150 pF1KB6 RNAGNAVRSAMKSEEQKIKDARKGPLVPFPNQKSEAAEPPKTPPSSCDSTNAAIAKQALK .. :: ::: .: .: . .. . :.:. XP_011 RMLGILHDAVVFLIEQLSGAKHCRNYKFRFHKPEEANEPPLNPHGSARA-EVHLRKSAFD 2920 2930 2940 2950 2960 2970 160 170 180 190 200 210 pF1KB6 KPIKGKQAPRKKAQGKTQQNRKLTDFYPVRRSSRKSKAELQSEERKRIDELIESGKEEGM . . : ... . . : . . .. . : .. .: : : .: ...:: .. XP_011 --MFNFLASKHRQPPEYNPNDEEEEEVQLKSARRATSMDLPMPMRFR--HLKKTSKE-AV 2980 2990 3000 3010 3020 220 230 240 250 260 270 pF1KB6 KIDLIDGKGRGVIATKQFSRGDFVVEYHGDLIEITDAKKREALYAQDPSTGCYMYYFQYL . .:::.. .... :..:.:: :..:. .. ::: : .. . ::::. . XP_011 GVYRSPIHGRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYY-DSKGIGCYMFR---I 3030 3040 3050 3060 3070 3080 280 290 300 310 320 330 pF1KB6 SKTYCVDATRETNRLGRLINHSKCGNCQTKLHDIDGVPHLILIASRDIAAGEELLYDYGD . . :::: . : .:.:::: :: ... .::: :....: : : :::: ::: XP_011 DDSEVVDATMHGNA-ARFINHSCEPNCYSRVINIDGQKHIVIFAMRKIYRGEELTYDYKF 3090 3100 3110 3120 3130 3140 340 350 pF1KB6 RSKASIEAHPWLKH XP_011 PIEDASNKLPCNCGAKKCRKFLN 3150 3160 >>NP_005924 (OMIM: 159555,605130) histone-lysine N-methy (3969 aa) initn: 295 init1: 143 opt: 258 Z-score: 219.6 bits: 52.6 E(85289): 1.7e-05 Smith-Waterman score: 278; 29.3% identity (60.6% similar) in 208 aa overlap (129-336:3748-3944) 100 110 120 130 140 150 pF1KB6 RNAGNAVRSAMKSEEQKIKDARKGPLVPFPNQKSEAAEPPKTPPSSCDSTNAAIAKQALK .. :: ::: .: .: . .. . :.:. NP_005 RMLGILHDAVVFLIEQLSGAKHCRNYKFRFHKPEEANEPPLNPHGSARA-EVHLRKSAFD 3720 3730 3740 3750 3760 3770 160 170 180 190 200 210 pF1KB6 KPIKGKQAPRKKAQGKTQQNRKLTDFYPVRRSSRKSKAELQSEERKRIDELIESGKEEGM . . : ... . . : . . .. . : .. .: : : .: ...:: .. NP_005 --MFNFLASKHRQPPEYNPNDEEEEEVQLKSARRATSMDLPMPMRFR--HLKKTSKE-AV 3780 3790 3800 3810 3820 3830 220 230 240 250 260 270 pF1KB6 KIDLIDGKGRGVIATKQFSRGDFVVEYHGDLIEITDAKKREALYAQDPSTGCYMYYFQYL . .:::.. .... :..:.:: :..:. .. ::: : .. . ::::. . NP_005 GVYRSPIHGRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYY-DSKGIGCYMFR---I 3840 3850 3860 3870 3880 280 290 300 310 320 330 pF1KB6 SKTYCVDATRETNRLGRLINHSKCGNCQTKLHDIDGVPHLILIASRDIAAGEELLYDYGD . . :::: . : .:.:::: :: ... .::: :....: : : :::: ::: NP_005 DDSEVVDATMHGNA-ARFINHSCEPNCYSRVINIDGQKHIVIFAMRKIYRGEELTYDYKF 3890 3900 3910 3920 3930 3940 340 350 pF1KB6 RSKASIEAHPWLKH NP_005 PIEDASNKLPCNCGAKKCRKFLN 3950 3960 >>NP_001184033 (OMIM: 159555,605130) histone-lysine N-me (3972 aa) initn: 295 init1: 143 opt: 258 Z-score: 219.6 bits: 52.6 E(85289): 1.7e-05 Smith-Waterman score: 278; 29.3% identity (60.6% similar) in 208 aa overlap (129-336:3751-3947) 100 110 120 130 140 150 pF1KB6 RNAGNAVRSAMKSEEQKIKDARKGPLVPFPNQKSEAAEPPKTPPSSCDSTNAAIAKQALK .. :: ::: .: .: . .. . :.:. NP_001 RMLGILHDAVVFLIEQLSGAKHCRNYKFRFHKPEEANEPPLNPHGSARA-EVHLRKSAFD 3730 3740 3750 3760 3770 160 170 180 190 200 210 pF1KB6 KPIKGKQAPRKKAQGKTQQNRKLTDFYPVRRSSRKSKAELQSEERKRIDELIESGKEEGM . . : ... . . : . . .. . : .. .: : : .: ...:: .. NP_001 --MFNFLASKHRQPPEYNPNDEEEEEVQLKSARRATSMDLPMPMRFR--HLKKTSKE-AV 3780 3790 3800 3810 3820 3830 220 230 240 250 260 270 pF1KB6 KIDLIDGKGRGVIATKQFSRGDFVVEYHGDLIEITDAKKREALYAQDPSTGCYMYYFQYL . .:::.. .... :..:.:: :..:. .. ::: : .. . ::::. . NP_001 GVYRSPIHGRGLFCKRNIDAGEMVIEYAGNVIRSIQTDKREKYY-DSKGIGCYMFR---I 3840 3850 3860 3870 3880 3890 280 290 300 310 320 330 pF1KB6 SKTYCVDATRETNRLGRLINHSKCGNCQTKLHDIDGVPHLILIASRDIAAGEELLYDYGD . . :::: . : .:.:::: :: ... .::: :....: : : :::: ::: NP_001 DDSEVVDATMHGNA-ARFINHSCEPNCYSRVINIDGQKHIVIFAMRKIYRGEELTYDYKF 3900 3910 3920 3930 3940 340 350 pF1KB6 RSKASIEAHPWLKH NP_001 PIEDASNKLPCNCGAKKCRKFLN 3950 3960 3970 352 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 01:06:04 2016 done: Sat Nov 5 01:06:05 2016 Total Scan time: 7.480 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]