FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6468, 354 aa 1>>>pF1KB6468 354 - 354 aa - 354 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.9245+/-0.000478; mu= 18.8896+/- 0.030 mean_var=67.9980+/-13.214, 0's: 0 Z-trim(108.8): 98 B-trim: 0 in 0/54 Lambda= 0.155534 statistics sampled from 16869 (16971) to 16869 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.541), E-opt: 0.2 (0.199), width: 16 Scan time: 6.570 The best scores are: opt bits E(85289) NP_006487 (OMIM: 139370,602483) guanine nucleotide ( 354) 2323 530.6 2e-150 NP_002060 (OMIM: 139310) guanine nucleotide-bindin ( 354) 2209 505.0 9.9e-143 NP_002061 (OMIM: 139360,192605) guanine nucleotide ( 355) 2051 469.6 4.7e-132 NP_001243343 (OMIM: 139310) guanine nucleotide-bin ( 302) 1893 434.1 1.9e-121 NP_001159897 (OMIM: 139360,192605) guanine nucleot ( 318) 1827 419.3 5.8e-117 NP_001269549 (OMIM: 139360,192605) guanine nucleot ( 339) 1827 419.3 6.1e-117 NP_001269548 (OMIM: 139360,192605) guanine nucleot ( 339) 1827 419.3 6.1e-117 NP_001269546 (OMIM: 139360,192605) guanine nucleot ( 303) 1748 401.6 1.2e-111 NP_005263 (OMIM: 139340,613856) guanine nucleotide ( 354) 1688 388.1 1.5e-107 XP_011539566 (OMIM: 139340,613856) PREDICTED: guan ( 354) 1688 388.1 1.5e-107 NP_001095856 (OMIM: 139395) guanine nucleotide-bin ( 354) 1678 385.9 7.3e-107 NP_620073 (OMIM: 139311,615473) guanine nucleotide ( 354) 1675 385.2 1.2e-106 NP_066268 (OMIM: 139311,615473) guanine nucleotide ( 354) 1667 383.4 4e-106 NP_653082 (OMIM: 139330,610444,616389) guanine nuc ( 350) 1607 370.0 4.5e-102 NP_000163 (OMIM: 139330,610444,616389) guanine nuc ( 350) 1607 370.0 4.5e-102 NP_002064 (OMIM: 139160) guanine nucleotide-bindin ( 355) 1589 365.9 7.5e-101 NP_001269547 (OMIM: 139360,192605) guanine nucleot ( 274) 1575 362.7 5.4e-100 XP_011521305 (OMIM: 139311,615473) PREDICTED: guan ( 312) 1393 321.9 1.2e-87 XP_011514426 (OMIM: 139395) PREDICTED: guanine nuc ( 297) 1375 317.8 1.9e-86 NP_004288 (OMIM: 604397) guanine nucleotide-bindin ( 355) 1146 266.5 6.3e-71 NP_002063 (OMIM: 163000,185300,600998) guanine nuc ( 359) 1144 266.1 8.7e-71 NP_002058 (OMIM: 139313) guanine nucleotide-bindin ( 359) 1114 259.3 9.2e-69 XP_016884275 (OMIM: 139160) PREDICTED: guanine nuc ( 307) 991 231.7 1.7e-60 XP_016870117 (OMIM: 163000,185300,600998) PREDICTE ( 301) 973 227.6 2.7e-59 XP_016870830 (OMIM: 604397) PREDICTED: guanine nuc ( 301) 971 227.2 3.7e-59 NP_031379 (OMIM: 604394) guanine nucleotide-bindin ( 381) 902 211.8 2e-54 NP_006563 (OMIM: 604406) guanine nucleotide-bindin ( 377) 892 209.5 9.5e-54 XP_011517526 (OMIM: 604397) PREDICTED: guanine nuc ( 237) 872 204.9 1.5e-52 NP_002059 (OMIM: 139314) guanine nucleotide-bindin ( 374) 874 205.5 1.5e-52 XP_016883302 (OMIM: 102200,103580,139320,166350,17 (1023) 818 193.3 2e-48 NP_536351 (OMIM: 102200,103580,139320,166350,17480 ( 380) 813 191.8 2.1e-48 NP_001070957 (OMIM: 102200,103580,139320,166350,17 ( 379) 812 191.6 2.4e-48 XP_016883303 (OMIM: 102200,103580,139320,166350,17 (1022) 816 192.8 2.8e-48 NP_892023 (OMIM: 139312,615073) guanine nucleotide ( 458) 812 191.7 2.8e-48 NP_001248372 (OMIM: 139312,615073) guanine nucleot ( 381) 795 187.8 3.4e-47 NP_001135811 (OMIM: 139312,615073) guanine nucleot ( 381) 795 187.8 3.4e-47 XP_016883304 (OMIM: 102200,103580,139320,166350,17 ( 347) 754 178.6 1.9e-44 XP_016867497 (OMIM: 604394) PREDICTED: guanine nuc ( 253) 745 176.4 5.9e-44 XP_011513590 (OMIM: 604394) PREDICTED: guanine nuc ( 284) 745 176.5 6.5e-44 NP_001269370 (OMIM: 604394) guanine nucleotide-bin ( 322) 745 176.5 7.1e-44 NP_001269354 (OMIM: 604406) guanine nucleotide-bin ( 282) 689 163.9 3.9e-40 XP_016883307 (OMIM: 102200,103580,139320,166350,17 ( 320) 673 160.4 5.2e-39 XP_016883306 (OMIM: 102200,103580,139320,166350,17 ( 320) 673 160.4 5.2e-39 XP_016883308 (OMIM: 102200,103580,139320,166350,17 ( 320) 673 160.4 5.2e-39 NP_001269369 (OMIM: 604394) guanine nucleotide-bin ( 305) 659 157.2 4.4e-38 NP_000507 (OMIM: 102200,103580,139320,166350,17480 ( 394) 645 154.1 4.7e-37 NP_001070956 (OMIM: 102200,103580,139320,166350,17 ( 395) 645 154.1 4.7e-37 NP_536350 (OMIM: 102200,103580,139320,166350,17480 (1037) 645 154.5 9.9e-37 XP_016883301 (OMIM: 102200,103580,139320,166350,17 (1038) 645 154.5 9.9e-37 NP_001296769 (OMIM: 102200,103580,139320,166350,17 ( 335) 639 152.7 1.1e-36 >>NP_006487 (OMIM: 139370,602483) guanine nucleotide-bin (354 aa) initn: 2323 init1: 2323 opt: 2323 Z-score: 2821.7 bits: 530.6 E(85289): 2e-150 Smith-Waterman score: 2323; 100.0% identity (100.0% similar) in 354 aa overlap (1-354:1-354) 10 20 30 40 50 60 pF1KB6 MGCTLSAEDKAAVERSKMIDRNLREDGEKAAKEVKLLLLGAGESGKSTIVKQMKIIHEDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 MGCTLSAEDKAAVERSKMIDRNLREDGEKAAKEVKLLLLGAGESGKSTIVKQMKIIHEDG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 YSEDECKQYKVVVYSNTIQSIIAIIRAMGRLKIDFGEAARADDARQLFVLAGSAEEGVMT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 YSEDECKQYKVVVYSNTIQSIIAIIRAMGRLKIDFGEAARADDARQLFVLAGSAEEGVMT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 PELAGVIKRLWRDGGVQACFSRSREYQLNDSASYYLNDLDRISQSNYIPTQQDVLRTRVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 PELAGVIKRLWRDGGVQACFSRSREYQLNDSASYYLNDLDRISQSNYIPTQQDVLRTRVK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 TTGIVETHFTFKDLYFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 TTGIVETHFTFKDLYFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 NRMHESMKLFDSICNNKWFTETSIILFLNKKDLFEEKIKRSPLTICYPEYTGSNTYEEAA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 NRMHESMKLFDSICNNKWFTETSIILFLNKKDLFEEKIKRSPLTICYPEYTGSNTYEEAA 250 260 270 280 290 300 310 320 330 340 350 pF1KB6 AYIQCQFEDLNRRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKECGLY :::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_006 AYIQCQFEDLNRRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKECGLY 310 320 330 340 350 >>NP_002060 (OMIM: 139310) guanine nucleotide-binding pr (354 aa) initn: 2230 init1: 2209 opt: 2209 Z-score: 2683.5 bits: 505.0 E(85289): 9.9e-143 Smith-Waterman score: 2209; 93.8% identity (98.9% similar) in 354 aa overlap (1-354:1-354) 10 20 30 40 50 60 pF1KB6 MGCTLSAEDKAAVERSKMIDRNLREDGEKAAKEVKLLLLGAGESGKSTIVKQMKIIHEDG :::::::::::::::::::::::::::::::.:::::::::::::::::::::::::: : NP_002 MGCTLSAEDKAAVERSKMIDRNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEAG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 YSEDECKQYKVVVYSNTIQSIIAIIRAMGRLKIDFGEAARADDARQLFVLAGSAEEGVMT :::.::::::.:::::::::::::::::::::::::..::::::::::::::.:::: :: NP_002 YSEEECKQYKAVVYSNTIQSIIAIIRAMGRLKIDFGDSARADDARQLFVLAGAAEEGFMT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 PELAGVIKRLWRDGGVQACFSRSREYQLNDSASYYLNDLDRISQSNYIPTQQDVLRTRVK ::::::::::.:.::::::.:::::::::::.:::::::::.: ::::::::::::::: NP_002 AELAGVIKRLWKDSGVQACFNRSREYQLNDSAAYYLNDLDRIAQPNYIPTQQDVLRTRVK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 TTGIVETHFTFKDLYFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEM ::::::::::::::.::::::::::::::::::::::::::::::::::::::::::::: NP_002 TTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 NRMHESMKLFDSICNNKWFTETSIILFLNKKDLFEEKIKRSPLTICYPEYTGSNTYEEAA ::::::::::::::::::::.::::::::::::::::::.::::::::::.::::::::: NP_002 NRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICYPEYAGSNTYEEAA 250 260 270 280 290 300 310 320 330 340 350 pF1KB6 AYIQCQFEDLNRRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKECGLY :::::::::::.:::::::::::::::::::::::::::::::::::::.:::. NP_002 AYIQCQFEDLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF 310 320 330 340 350 >>NP_002061 (OMIM: 139360,192605) guanine nucleotide-bin (355 aa) initn: 2076 init1: 1437 opt: 2051 Z-score: 2491.9 bits: 469.6 E(85289): 4.7e-132 Smith-Waterman score: 2051; 85.9% identity (96.6% similar) in 355 aa overlap (1-354:1-355) 10 20 30 40 50 60 pF1KB6 MGCTLSAEDKAAVERSKMIDRNLREDGEKAAKEVKLLLLGAGESGKSTIVKQMKIIHEDG ::::.:::::::.:::::::.::::::::::.:::::::::::::::::::::::::::: NP_002 MGCTVSAEDKAAAERSKMIDKNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEDG 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 YSEDECKQYKVVVYSNTIQSIIAIIRAMGRLKIDFGEAARADDARQLFVLAGSAEE-GVM :::.::.::..::::::::::.::..::: :.:::.. .:::::::::.:. .::: ::. NP_002 YSEEECRQYRAVVYSNTIQSIMAIVKAMGNLQIDFADPSRADDARQLFALSCTAEEQGVL 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 TPELAGVIKRLWRDGGVQACFSRSREYQLNDSASYYLNDLDRISQSNYIPTQQDVLRTRV .:.:::.::: : ::::::.:::::::::::.::::::.::.::.::::::::::::: NP_002 PDDLSGVIRRLWADHGVQACFGRSREYQLNDSAAYYLNDLERIAQSDYIPTQQDVLRTRV 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB6 KTTGIVETHFTFKDLYFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEE :::::::::::::::.::::::::::::::::::::::::::::::::: :::::::::: NP_002 KTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSAYDLVLAEDEE 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB6 MNRMHESMKLFDSICNNKWFTETSIILFLNKKDLFEEKIKRSPLTICYPEYTGSNTYEEA :::::::::::::::::::::.::::::::::::::::: .::::::.:::::.: :.:: NP_002 MNRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKITHSPLTICFPEYTGANKYDEA 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB6 AAYIQCQFEDLNRRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKECGLY :.::: .:::::.:::::::::::::::::::::::::::::::::::::.:::. NP_002 ASYIQSKFEDLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF 310 320 330 340 350 >>NP_001243343 (OMIM: 139310) guanine nucleotide-binding (302 aa) initn: 1914 init1: 1893 opt: 1893 Z-score: 2301.2 bits: 434.1 E(85289): 1.9e-121 Smith-Waterman score: 1893; 93.0% identity (98.7% similar) in 302 aa overlap (53-354:1-302) 30 40 50 60 70 80 pF1KB6 LREDGEKAAKEVKLLLLGAGESGKSTIVKQMKIIHEDGYSEDECKQYKVVVYSNTIQSII :::::: ::::.::::::.::::::::::: NP_001 MKIIHEAGYSEEECKQYKAVVYSNTIQSII 10 20 30 90 100 110 120 130 140 pF1KB6 AIIRAMGRLKIDFGEAARADDARQLFVLAGSAEEGVMTPELAGVIKRLWRDGGVQACFSR ::::::::::::::..::::::::::::::.:::: :: ::::::::::.:.::::::.: NP_001 AIIRAMGRLKIDFGDSARADDARQLFVLAGAAEEGFMTAELAGVIKRLWKDSGVQACFNR 40 50 60 70 80 90 150 160 170 180 190 200 pF1KB6 SREYQLNDSASYYLNDLDRISQSNYIPTQQDVLRTRVKTTGIVETHFTFKDLYFKMFDVG ::::::::::.:::::::::.: :::::::::::::::::::::::::::::.::::::: NP_001 SREYQLNDSAAYYLNDLDRIAQPNYIPTQQDVLRTRVKTTGIVETHFTFKDLHFKMFDVG 100 110 120 130 140 150 210 220 230 240 250 260 pF1KB6 GQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEMNRMHESMKLFDSICNNKWFTET ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::.: NP_001 GQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEMNRMHESMKLFDSICNNKWFTDT 160 170 180 190 200 210 270 280 290 300 310 320 pF1KB6 SIILFLNKKDLFEEKIKRSPLTICYPEYTGSNTYEEAAAYIQCQFEDLNRRKDTKEIYTH :::::::::::::::::.::::::::::.::::::::::::::::::::.:::::::::: NP_001 SIILFLNKKDLFEEKIKKSPLTICYPEYAGSNTYEEAAAYIQCQFEDLNKRKDTKEIYTH 220 230 240 250 260 270 330 340 350 pF1KB6 FTCATDTKNVQFVFDAVTDVIIKNNLKECGLY :::::::::::::::::::::::::::.:::. NP_001 FTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF 280 290 300 >>NP_001159897 (OMIM: 139360,192605) guanine nucleotide- (318 aa) initn: 1852 init1: 1437 opt: 1827 Z-score: 2220.9 bits: 419.3 E(85289): 5.8e-117 Smith-Waterman score: 1827; 85.4% identity (96.2% similar) in 316 aa overlap (40-354:3-318) 10 20 30 40 50 60 pF1KB6 KAAVERSKMIDRNLREDGEKAAKEVKLLLLGAGESGKSTIVKQMKIIHEDGYSEDECKQY ::::::::::::::::::::::::.::.:: NP_001 MRGAGESGKSTIVKQMKIIHEDGYSEEECRQY 10 20 30 70 80 90 100 110 120 pF1KB6 KVVVYSNTIQSIIAIIRAMGRLKIDFGEAARADDARQLFVLAGSAEE-GVMTPELAGVIK ..::::::::::.::..::: :.:::.. .:::::::::.:. .::: ::. .:.:::. NP_001 RAVVYSNTIQSIMAIVKAMGNLQIDFADPSRADDARQLFALSCTAEEQGVLPDDLSGVIR 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB6 RLWRDGGVQACFSRSREYQLNDSASYYLNDLDRISQSNYIPTQQDVLRTRVKTTGIVETH ::: : ::::::.:::::::::::.::::::.::.::.:::::::::::::::::::::: NP_001 RLWADHGVQACFGRSREYQLNDSAAYYLNDLERIAQSDYIPTQQDVLRTRVKTTGIVETH 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB6 FTFKDLYFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEMNRMHESMK ::::::.::::::::::::::::::::::::::::::::: ::::::::::::::::::: NP_001 FTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSAYDLVLAEDEEMNRMHESMK 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB6 LFDSICNNKWFTETSIILFLNKKDLFEEKIKRSPLTICYPEYTGSNTYEEAAAYIQCQFE ::::::::::::.::::::::::::::::: .::::::.:::::.: :.:::.::: .:: NP_001 LFDSICNNKWFTDTSIILFLNKKDLFEEKITHSPLTICFPEYTGANKYDEAASYIQSKFE 220 230 240 250 260 270 310 320 330 340 350 pF1KB6 DLNRRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKECGLY :::.:::::::::::::::::::::::::::::::::::::.:::. NP_001 DLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF 280 290 300 310 >>NP_001269549 (OMIM: 139360,192605) guanine nucleotide- (339 aa) initn: 1852 init1: 1437 opt: 1827 Z-score: 2220.5 bits: 419.3 E(85289): 6.1e-117 Smith-Waterman score: 1827; 85.4% identity (96.2% similar) in 316 aa overlap (40-354:24-339) 10 20 30 40 50 60 pF1KB6 KAAVERSKMIDRNLREDGEKAAKEVKLLLLGAGESGKSTIVKQMKIIHEDGYSEDECKQY ::::::::::::::::::::::::.::.:: NP_001 MTEGVKTLGWTKQKGGCHWGRSEGAGESGKSTIVKQMKIIHEDGYSEEECRQY 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 KVVVYSNTIQSIIAIIRAMGRLKIDFGEAARADDARQLFVLAGSAEE-GVMTPELAGVIK ..::::::::::.::..::: :.:::.. .:::::::::.:. .::: ::. .:.:::. NP_001 RAVVYSNTIQSIMAIVKAMGNLQIDFADPSRADDARQLFALSCTAEEQGVLPDDLSGVIR 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 RLWRDGGVQACFSRSREYQLNDSASYYLNDLDRISQSNYIPTQQDVLRTRVKTTGIVETH ::: : ::::::.:::::::::::.::::::.::.::.:::::::::::::::::::::: NP_001 RLWADHGVQACFGRSREYQLNDSAAYYLNDLERIAQSDYIPTQQDVLRTRVKTTGIVETH 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB6 FTFKDLYFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEMNRMHESMK ::::::.::::::::::::::::::::::::::::::::: ::::::::::::::::::: NP_001 FTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSAYDLVLAEDEEMNRMHESMK 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB6 LFDSICNNKWFTETSIILFLNKKDLFEEKIKRSPLTICYPEYTGSNTYEEAAAYIQCQFE ::::::::::::.::::::::::::::::: .::::::.:::::.: :.:::.::: .:: NP_001 LFDSICNNKWFTDTSIILFLNKKDLFEEKITHSPLTICFPEYTGANKYDEAASYIQSKFE 240 250 260 270 280 290 310 320 330 340 350 pF1KB6 DLNRRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKECGLY :::.:::::::::::::::::::::::::::::::::::::.:::. NP_001 DLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF 300 310 320 330 >>NP_001269548 (OMIM: 139360,192605) guanine nucleotide- (339 aa) initn: 1852 init1: 1437 opt: 1827 Z-score: 2220.5 bits: 419.3 E(85289): 6.1e-117 Smith-Waterman score: 1827; 85.4% identity (96.2% similar) in 316 aa overlap (40-354:24-339) 10 20 30 40 50 60 pF1KB6 KAAVERSKMIDRNLREDGEKAAKEVKLLLLGAGESGKSTIVKQMKIIHEDGYSEDECKQY ::::::::::::::::::::::::.::.:: NP_001 MEYAGHLPASSAQGTILACTSCTGAGESGKSTIVKQMKIIHEDGYSEEECRQY 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 KVVVYSNTIQSIIAIIRAMGRLKIDFGEAARADDARQLFVLAGSAEE-GVMTPELAGVIK ..::::::::::.::..::: :.:::.. .:::::::::.:. .::: ::. .:.:::. NP_001 RAVVYSNTIQSIMAIVKAMGNLQIDFADPSRADDARQLFALSCTAEEQGVLPDDLSGVIR 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 RLWRDGGVQACFSRSREYQLNDSASYYLNDLDRISQSNYIPTQQDVLRTRVKTTGIVETH ::: : ::::::.:::::::::::.::::::.::.::.:::::::::::::::::::::: NP_001 RLWADHGVQACFGRSREYQLNDSAAYYLNDLERIAQSDYIPTQQDVLRTRVKTTGIVETH 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB6 FTFKDLYFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEMNRMHESMK ::::::.::::::::::::::::::::::::::::::::: ::::::::::::::::::: NP_001 FTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSAYDLVLAEDEEMNRMHESMK 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB6 LFDSICNNKWFTETSIILFLNKKDLFEEKIKRSPLTICYPEYTGSNTYEEAAAYIQCQFE ::::::::::::.::::::::::::::::: .::::::.:::::.: :.:::.::: .:: NP_001 LFDSICNNKWFTDTSIILFLNKKDLFEEKITHSPLTICFPEYTGANKYDEAASYIQSKFE 240 250 260 270 280 290 310 320 330 340 350 pF1KB6 DLNRRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKECGLY :::.:::::::::::::::::::::::::::::::::::::.:::. NP_001 DLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF 300 310 320 330 >>NP_001269546 (OMIM: 139360,192605) guanine nucleotide- (303 aa) initn: 1773 init1: 1437 opt: 1748 Z-score: 2125.4 bits: 401.6 E(85289): 1.2e-111 Smith-Waterman score: 1748; 84.8% identity (96.0% similar) in 303 aa overlap (53-354:1-303) 30 40 50 60 70 80 pF1KB6 LREDGEKAAKEVKLLLLGAGESGKSTIVKQMKIIHEDGYSEDECKQYKVVVYSNTIQSII :::::::::::.::.::..::::::::::. NP_001 MKIIHEDGYSEEECRQYRAVVYSNTIQSIM 10 20 30 90 100 110 120 130 140 pF1KB6 AIIRAMGRLKIDFGEAARADDARQLFVLAGSAEE-GVMTPELAGVIKRLWRDGGVQACFS ::..::: :.:::.. .:::::::::.:. .::: ::. .:.:::.::: : ::::::. NP_001 AIVKAMGNLQIDFADPSRADDARQLFALSCTAEEQGVLPDDLSGVIRRLWADHGVQACFG 40 50 60 70 80 90 150 160 170 180 190 200 pF1KB6 RSREYQLNDSASYYLNDLDRISQSNYIPTQQDVLRTRVKTTGIVETHFTFKDLYFKMFDV :::::::::::.::::::.::.::.::::::::::::::::::::::::::::.:::::: NP_001 RSREYQLNDSAAYYLNDLERIAQSDYIPTQQDVLRTRVKTTGIVETHFTFKDLHFKMFDV 100 110 120 130 140 150 210 220 230 240 250 260 pF1KB6 GGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEMNRMHESMKLFDSICNNKWFTE ::::::::::::::::::::::::::: :::::::::::::::::::::::::::::::. NP_001 GGQRSERKKWIHCFEGVTAIIFCVALSAYDLVLAEDEEMNRMHESMKLFDSICNNKWFTD 160 170 180 190 200 210 270 280 290 300 310 320 pF1KB6 TSIILFLNKKDLFEEKIKRSPLTICYPEYTGSNTYEEAAAYIQCQFEDLNRRKDTKEIYT ::::::::::::::::: .::::::.:::::.: :.:::.::: .:::::.::::::::: NP_001 TSIILFLNKKDLFEEKITHSPLTICFPEYTGANKYDEAASYIQSKFEDLNKRKDTKEIYT 220 230 240 250 260 270 330 340 350 pF1KB6 HFTCATDTKNVQFVFDAVTDVIIKNNLKECGLY ::::::::::::::::::::::::::::.:::. NP_001 HFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF 280 290 300 >>NP_005263 (OMIM: 139340,613856) guanine nucleotide-bin (354 aa) initn: 1688 init1: 1688 opt: 1688 Z-score: 2051.7 bits: 388.1 E(85289): 1.5e-107 Smith-Waterman score: 1688; 69.5% identity (89.8% similar) in 354 aa overlap (1-354:1-354) 10 20 30 40 50 60 pF1KB6 MGCTLSAEDKAAVERSKMIDRNLREDGEKAAKEVKLLLLGAGESGKSTIVKQMKIIHEDG :: ::::: ..::: ....:.::..: :: ::::::::::::::::::::::::.:: NP_005 MGSGASAEDKELAKRSKELEKKLQEDADKEAKTVKLLLLGAGESGKSTIVKQMKIIHQDG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 YSEDECKQYKVVVYSNTIQSIIAIIRAMGRLKIDFGEAARADDARQLFVLAGSAEEGVMT :: .:: ..:...:.:..:::.:::::: : ::..: . :::.::: :: : :::.: NP_005 YSPEECLEFKAIIYGNVLQSILAIIRAMTTLGIDYAEPSCADDGRQLNNLADSIEEGTMP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 PELAGVIKRLWRDGGVQACFSRSREYQLNDSASYYLNDLDRISQSNYIPTQQDVLRTRVK :::. ::.:::.:::::::: :. :::::::::::::.:.::.. .:.:..:::::.::: NP_005 PELVEVIRRLWKDGGVQACFERAAEYQLNDSASYYLNQLERITDPEYLPSEQDVLRSRVK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 TTGIVETHFTFKDLYFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEM ::::.::.:. ::: :.:::::::::::::::::::::: ::::.::: ::.::.::.:. NP_005 TTGIIETKFSVKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFCAALSAYDMVLVEDDEV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 NRMHESMKLFDSICNNKWFTETSIILFLNKKDLFEEKIKRSPLTICYPEYTGSNTYEEAA ::::::..::.::::.:.:. :::.::::::::::::::. :.::.::: :.:.:..:. NP_005 NRMHESLHLFNSICNHKFFAATSIVLFLNKKDLFEEKIKKVHLSICFPEYDGNNSYDDAG 250 260 270 280 290 300 310 320 330 340 350 pF1KB6 AYIQCQFEDLNRRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKECGLY ::. :: ::: :::.::::.:.::::::.::.::::::::.:::.:::.:::. NP_005 NYIKSQFLDLNMRKDVKEIYSHMTCATDTQNVKFVFDAVTDIIIKENLKDCGLF 310 320 330 340 350 >>XP_011539566 (OMIM: 139340,613856) PREDICTED: guanine (354 aa) initn: 1688 init1: 1688 opt: 1688 Z-score: 2051.7 bits: 388.1 E(85289): 1.5e-107 Smith-Waterman score: 1688; 69.5% identity (89.8% similar) in 354 aa overlap (1-354:1-354) 10 20 30 40 50 60 pF1KB6 MGCTLSAEDKAAVERSKMIDRNLREDGEKAAKEVKLLLLGAGESGKSTIVKQMKIIHEDG :: ::::: ..::: ....:.::..: :: ::::::::::::::::::::::::.:: XP_011 MGSGASAEDKELAKRSKELEKKLQEDADKEAKTVKLLLLGAGESGKSTIVKQMKIIHQDG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 YSEDECKQYKVVVYSNTIQSIIAIIRAMGRLKIDFGEAARADDARQLFVLAGSAEEGVMT :: .:: ..:...:.:..:::.:::::: : ::..: . :::.::: :: : :::.: XP_011 YSPEECLEFKAIIYGNVLQSILAIIRAMTTLGIDYAEPSCADDGRQLNNLADSIEEGTMP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 PELAGVIKRLWRDGGVQACFSRSREYQLNDSASYYLNDLDRISQSNYIPTQQDVLRTRVK :::. ::.:::.:::::::: :. :::::::::::::.:.::.. .:.:..:::::.::: XP_011 PELVEVIRRLWKDGGVQACFERAAEYQLNDSASYYLNQLERITDPEYLPSEQDVLRSRVK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 TTGIVETHFTFKDLYFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEM ::::.::.:. ::: :.:::::::::::::::::::::: ::::.::: ::.::.::.:. XP_011 TTGIIETKFSVKDLNFRMFDVGGQRSERKKWIHCFEGVTCIIFCAALSAYDMVLVEDDEV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 NRMHESMKLFDSICNNKWFTETSIILFLNKKDLFEEKIKRSPLTICYPEYTGSNTYEEAA ::::::..::.::::.:.:. :::.::::::::::::::. :.::.::: :.:.:..:. XP_011 NRMHESLHLFNSICNHKFFAATSIVLFLNKKDLFEEKIKKVHLSICFPEYDGNNSYDDAG 250 260 270 280 290 300 310 320 330 340 350 pF1KB6 AYIQCQFEDLNRRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKECGLY ::. :: ::: :::.::::.:.::::::.::.::::::::.:::.:::.:::. XP_011 NYIKSQFLDLNMRKDVKEIYSHMTCATDTQNVKFVFDAVTDIIIKENLKDCGLF 310 320 330 340 350 354 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 23:05:22 2016 done: Fri Nov 4 23:05:23 2016 Total Scan time: 6.570 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]