FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6472, 355 aa 1>>>pF1KB6472 355 - 355 aa - 355 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.3635+/-0.000471; mu= 22.3254+/- 0.029 mean_var=68.3922+/-13.810, 0's: 0 Z-trim(109.1): 96 B-trim: 514 in 2/52 Lambda= 0.155085 statistics sampled from 17131 (17237) to 17131 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.557), E-opt: 0.2 (0.202), width: 16 Scan time: 7.360 The best scores are: opt bits E(85289) NP_002061 (OMIM: 139360,192605) guanine nucleotide ( 355) 2345 534.0 1.9e-151 NP_001159897 (OMIM: 139360,192605) guanine nucleot ( 318) 2105 480.3 2.5e-135 NP_001269549 (OMIM: 139360,192605) guanine nucleot ( 339) 2105 480.3 2.7e-135 NP_001269548 (OMIM: 139360,192605) guanine nucleot ( 339) 2105 480.3 2.7e-135 NP_002060 (OMIM: 139310) guanine nucleotide-bindin ( 354) 2077 474.1 2.1e-133 NP_006487 (OMIM: 139370,602483) guanine nucleotide ( 354) 2051 468.2 1.2e-131 NP_001269546 (OMIM: 139360,192605) guanine nucleot ( 303) 2026 462.6 5.2e-130 NP_001269547 (OMIM: 139360,192605) guanine nucleot ( 274) 1836 420.0 3e-117 NP_001243343 (OMIM: 139310) guanine nucleotide-bin ( 302) 1770 405.3 9e-113 NP_001095856 (OMIM: 139395) guanine nucleotide-bin ( 354) 1697 389.0 8.3e-108 XP_011539566 (OMIM: 139340,613856) PREDICTED: guan ( 354) 1690 387.5 2.4e-107 NP_005263 (OMIM: 139340,613856) guanine nucleotide ( 354) 1690 387.5 2.4e-107 NP_620073 (OMIM: 139311,615473) guanine nucleotide ( 354) 1667 382.3 8.7e-106 NP_066268 (OMIM: 139311,615473) guanine nucleotide ( 354) 1646 377.6 2.2e-104 NP_000163 (OMIM: 139330,610444,616389) guanine nuc ( 350) 1605 368.5 1.3e-101 NP_653082 (OMIM: 139330,610444,616389) guanine nuc ( 350) 1605 368.5 1.3e-101 NP_002064 (OMIM: 139160) guanine nucleotide-bindin ( 355) 1588 364.7 1.8e-100 XP_011514426 (OMIM: 139395) PREDICTED: guanine nuc ( 297) 1394 321.2 1.9e-87 XP_011521305 (OMIM: 139311,615473) PREDICTED: guan ( 312) 1379 317.8 2e-86 NP_002063 (OMIM: 163000,185300,600998) guanine nuc ( 359) 1142 264.9 2e-70 NP_004288 (OMIM: 604397) guanine nucleotide-bindin ( 355) 1140 264.4 2.7e-70 NP_002058 (OMIM: 139313) guanine nucleotide-bindin ( 359) 1126 261.3 2.4e-69 XP_016884275 (OMIM: 139160) PREDICTED: guanine nuc ( 307) 1015 236.4 6.4e-62 XP_016870117 (OMIM: 163000,185300,600998) PREDICTE ( 301) 974 227.2 3.7e-59 XP_016870830 (OMIM: 604397) PREDICTED: guanine nuc ( 301) 967 225.6 1.1e-58 NP_006563 (OMIM: 604406) guanine nucleotide-bindin ( 377) 908 212.5 1.2e-54 NP_002059 (OMIM: 139314) guanine nucleotide-bindin ( 374) 877 205.6 1.5e-52 NP_031379 (OMIM: 604394) guanine nucleotide-bindin ( 381) 871 204.3 3.7e-52 XP_011517526 (OMIM: 604397) PREDICTED: guanine nuc ( 237) 866 202.9 5.9e-52 XP_016883303 (OMIM: 102200,103580,139320,166350,17 (1022) 824 194.2 1.1e-48 NP_001070957 (OMIM: 102200,103580,139320,166350,17 ( 379) 819 192.6 1.2e-48 XP_016883302 (OMIM: 102200,103580,139320,166350,17 (1023) 818 192.9 2.7e-48 NP_536351 (OMIM: 102200,103580,139320,166350,17480 ( 380) 813 191.3 3e-48 NP_892023 (OMIM: 139312,615073) guanine nucleotide ( 458) 806 189.8 1e-47 NP_001248372 (OMIM: 139312,615073) guanine nucleot ( 381) 797 187.7 3.6e-47 NP_001135811 (OMIM: 139312,615073) guanine nucleot ( 381) 797 187.7 3.6e-47 XP_016883304 (OMIM: 102200,103580,139320,166350,17 ( 347) 758 178.9 1.4e-44 XP_016867497 (OMIM: 604394) PREDICTED: guanine nuc ( 253) 712 168.5 1.4e-41 XP_011513590 (OMIM: 604394) PREDICTED: guanine nuc ( 284) 712 168.6 1.6e-41 NP_001269370 (OMIM: 604394) guanine nucleotide-bin ( 322) 712 168.6 1.7e-41 NP_001269354 (OMIM: 604406) guanine nucleotide-bin ( 282) 688 163.2 6.4e-40 XP_016883308 (OMIM: 102200,103580,139320,166350,17 ( 320) 677 160.8 3.9e-39 XP_016883306 (OMIM: 102200,103580,139320,166350,17 ( 320) 677 160.8 3.9e-39 XP_016883307 (OMIM: 102200,103580,139320,166350,17 ( 320) 677 160.8 3.9e-39 NP_001070956 (OMIM: 102200,103580,139320,166350,17 ( 395) 653 155.5 1.8e-37 NP_000507 (OMIM: 102200,103580,139320,166350,17480 ( 394) 651 155.1 2.5e-37 XP_016883309 (OMIM: 102200,103580,139320,166350,17 ( 320) 650 154.7 2.5e-37 XP_016883305 (OMIM: 102200,103580,139320,166350,17 ( 320) 650 154.7 2.5e-37 NP_001296769 (OMIM: 102200,103580,139320,166350,17 ( 335) 649 154.5 3.1e-37 NP_001296790 (OMIM: 102200,103580,139320,166350,17 ( 335) 649 154.5 3.1e-37 >>NP_002061 (OMIM: 139360,192605) guanine nucleotide-bin (355 aa) initn: 2345 init1: 2345 opt: 2345 Z-score: 2840.1 bits: 534.0 E(85289): 1.9e-151 Smith-Waterman score: 2345; 100.0% identity (100.0% similar) in 355 aa overlap (1-355:1-355) 10 20 30 40 50 60 pF1KB6 MGCTVSAEDKAAAERSKMIDKNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEDG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MGCTVSAEDKAAAERSKMIDKNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEDG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 YSEEECRQYRAVVYSNTIQSIMAIVKAMGNLQIDFADPSRADDARQLFALSCTAEEQGVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 YSEEECRQYRAVVYSNTIQSIMAIVKAMGNLQIDFADPSRADDARQLFALSCTAEEQGVL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 PDDLSGVIRRLWADHGVQACFGRSREYQLNDSAAYYLNDLERIAQSDYIPTQQDVLRTRV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 PDDLSGVIRRLWADHGVQACFGRSREYQLNDSAAYYLNDLERIAQSDYIPTQQDVLRTRV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 KTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSAYDLVLAEDEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 KTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSAYDLVLAEDEE 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 MNRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKITHSPLTICFPEYTGANKYDEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MNRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKITHSPLTICFPEYTGANKYDEA 250 260 270 280 290 300 310 320 330 340 350 pF1KB6 ASYIQSKFEDLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF ::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 ASYIQSKFEDLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF 310 320 330 340 350 >>NP_001159897 (OMIM: 139360,192605) guanine nucleotide- (318 aa) initn: 2105 init1: 2105 opt: 2105 Z-score: 2550.4 bits: 480.3 E(85289): 2.5e-135 Smith-Waterman score: 2105; 100.0% identity (100.0% similar) in 316 aa overlap (40-355:3-318) 10 20 30 40 50 60 pF1KB6 KAAAERSKMIDKNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEDGYSEEECRQY :::::::::::::::::::::::::::::: NP_001 MRGAGESGKSTIVKQMKIIHEDGYSEEECRQY 10 20 30 70 80 90 100 110 120 pF1KB6 RAVVYSNTIQSIMAIVKAMGNLQIDFADPSRADDARQLFALSCTAEEQGVLPDDLSGVIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RAVVYSNTIQSIMAIVKAMGNLQIDFADPSRADDARQLFALSCTAEEQGVLPDDLSGVIR 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB6 RLWADHGVQACFGRSREYQLNDSAAYYLNDLERIAQSDYIPTQQDVLRTRVKTTGIVETH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RLWADHGVQACFGRSREYQLNDSAAYYLNDLERIAQSDYIPTQQDVLRTRVKTTGIVETH 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB6 FTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSAYDLVLAEDEEMNRMHESMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSAYDLVLAEDEEMNRMHESMK 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB6 LFDSICNNKWFTDTSIILFLNKKDLFEEKITHSPLTICFPEYTGANKYDEAASYIQSKFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LFDSICNNKWFTDTSIILFLNKKDLFEEKITHSPLTICFPEYTGANKYDEAASYIQSKFE 220 230 240 250 260 270 310 320 330 340 350 pF1KB6 DLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF :::::::::::::::::::::::::::::::::::::::::::::: NP_001 DLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF 280 290 300 310 >>NP_001269549 (OMIM: 139360,192605) guanine nucleotide- (339 aa) initn: 2105 init1: 2105 opt: 2105 Z-score: 2550.1 bits: 480.3 E(85289): 2.7e-135 Smith-Waterman score: 2105; 100.0% identity (100.0% similar) in 316 aa overlap (40-355:24-339) 10 20 30 40 50 60 pF1KB6 KAAAERSKMIDKNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEDGYSEEECRQY :::::::::::::::::::::::::::::: NP_001 MTEGVKTLGWTKQKGGCHWGRSEGAGESGKSTIVKQMKIIHEDGYSEEECRQY 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 RAVVYSNTIQSIMAIVKAMGNLQIDFADPSRADDARQLFALSCTAEEQGVLPDDLSGVIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RAVVYSNTIQSIMAIVKAMGNLQIDFADPSRADDARQLFALSCTAEEQGVLPDDLSGVIR 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 RLWADHGVQACFGRSREYQLNDSAAYYLNDLERIAQSDYIPTQQDVLRTRVKTTGIVETH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RLWADHGVQACFGRSREYQLNDSAAYYLNDLERIAQSDYIPTQQDVLRTRVKTTGIVETH 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB6 FTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSAYDLVLAEDEEMNRMHESMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSAYDLVLAEDEEMNRMHESMK 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB6 LFDSICNNKWFTDTSIILFLNKKDLFEEKITHSPLTICFPEYTGANKYDEAASYIQSKFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LFDSICNNKWFTDTSIILFLNKKDLFEEKITHSPLTICFPEYTGANKYDEAASYIQSKFE 240 250 260 270 280 290 310 320 330 340 350 pF1KB6 DLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF :::::::::::::::::::::::::::::::::::::::::::::: NP_001 DLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF 300 310 320 330 >>NP_001269548 (OMIM: 139360,192605) guanine nucleotide- (339 aa) initn: 2105 init1: 2105 opt: 2105 Z-score: 2550.1 bits: 480.3 E(85289): 2.7e-135 Smith-Waterman score: 2105; 100.0% identity (100.0% similar) in 316 aa overlap (40-355:24-339) 10 20 30 40 50 60 pF1KB6 KAAAERSKMIDKNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEDGYSEEECRQY :::::::::::::::::::::::::::::: NP_001 MEYAGHLPASSAQGTILACTSCTGAGESGKSTIVKQMKIIHEDGYSEEECRQY 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 RAVVYSNTIQSIMAIVKAMGNLQIDFADPSRADDARQLFALSCTAEEQGVLPDDLSGVIR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RAVVYSNTIQSIMAIVKAMGNLQIDFADPSRADDARQLFALSCTAEEQGVLPDDLSGVIR 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 RLWADHGVQACFGRSREYQLNDSAAYYLNDLERIAQSDYIPTQQDVLRTRVKTTGIVETH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RLWADHGVQACFGRSREYQLNDSAAYYLNDLERIAQSDYIPTQQDVLRTRVKTTGIVETH 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB6 FTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSAYDLVLAEDEEMNRMHESMK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSAYDLVLAEDEEMNRMHESMK 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB6 LFDSICNNKWFTDTSIILFLNKKDLFEEKITHSPLTICFPEYTGANKYDEAASYIQSKFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LFDSICNNKWFTDTSIILFLNKKDLFEEKITHSPLTICFPEYTGANKYDEAASYIQSKFE 240 250 260 270 280 290 310 320 330 340 350 pF1KB6 DLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF :::::::::::::::::::::::::::::::::::::::::::::: NP_001 DLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF 300 310 320 330 >>NP_002060 (OMIM: 139310) guanine nucleotide-binding pr (354 aa) initn: 1468 init1: 1468 opt: 2077 Z-score: 2516.0 bits: 474.1 E(85289): 2.1e-133 Smith-Waterman score: 2077; 87.9% identity (95.8% similar) in 355 aa overlap (1-355:1-354) 10 20 30 40 50 60 pF1KB6 MGCTVSAEDKAAAERSKMIDKNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEDG ::::.:::::::.:::::::.::::::::::::::::::::::::::::::::::::: : NP_002 MGCTLSAEDKAAVERSKMIDRNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEAG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 YSEEECRQYRAVVYSNTIQSIMAIVKAMGNLQIDFADPSRADDARQLFALSCTAEEQGVL ::::::.::.:::::::::::.::..::: :.:::.: .:::::::::.:. .::: : . NP_002 YSEEECKQYKAVVYSNTIQSIIAIIRAMGRLKIDFGDSARADDARQLFVLAGAAEE-GFM 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 PDDLSGVIRRLWADHGVQACFGRSREYQLNDSAAYYLNDLERIAQSDYIPTQQDVLRTRV .:.:::.::: : ::::::.::::::::::::::::::.:::: .::::::::::::: NP_002 TAELAGVIKRLWKDSGVQACFNRSREYQLNDSAAYYLNDLDRIAQPNYIPTQQDVLRTRV 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB6 KTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSAYDLVLAEDEE ::::::::::::::::::::::::::::::::::::::::::::::::: :::::::::: NP_002 KTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEE 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB6 MNRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKITHSPLTICFPEYTGANKYDEA ::::::::::::::::::::::::::::::::::::::: .::::::.:::.:.: :.:: NP_002 MNRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICYPEYAGSNTYEEA 240 250 260 270 280 290 310 320 330 340 350 pF1KB6 ASYIQSKFEDLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF :.::: .:::::::::::::::::::::::::::::::::::::::::::::::: NP_002 AAYIQCQFEDLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF 300 310 320 330 340 350 >>NP_006487 (OMIM: 139370,602483) guanine nucleotide-bin (354 aa) initn: 2076 init1: 1437 opt: 2051 Z-score: 2484.6 bits: 468.2 E(85289): 1.2e-131 Smith-Waterman score: 2051; 85.9% identity (96.6% similar) in 355 aa overlap (1-355:1-354) 10 20 30 40 50 60 pF1KB6 MGCTVSAEDKAAAERSKMIDKNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEDG ::::.:::::::.:::::::.::::::::::.:::::::::::::::::::::::::::: NP_006 MGCTLSAEDKAAVERSKMIDRNLREDGEKAAKEVKLLLLGAGESGKSTIVKQMKIIHEDG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 YSEEECRQYRAVVYSNTIQSIMAIVKAMGNLQIDFADPSRADDARQLFALSCTAEEQGVL :::.::.::..::::::::::.::..::: :.:::.. .:::::::::.:. .::: ::. NP_006 YSEDECKQYKVVVYSNTIQSIIAIIRAMGRLKIDFGEAARADDARQLFVLAGSAEE-GVM 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 PDDLSGVIRRLWADHGVQACFGRSREYQLNDSAAYYLNDLERIAQSDYIPTQQDVLRTRV .:.:::.::: : ::::::.:::::::::::.::::::.::.::.::::::::::::: NP_006 TPELAGVIKRLWRDGGVQACFSRSREYQLNDSASYYLNDLDRISQSNYIPTQQDVLRTRV 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB6 KTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSAYDLVLAEDEE :::::::::::::::.::::::::::::::::::::::::::::::::: :::::::::: NP_006 KTTGIVETHFTFKDLYFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEE 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB6 MNRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKITHSPLTICFPEYTGANKYDEA :::::::::::::::::::::.::::::::::::::::: .::::::.:::::.: :.:: NP_006 MNRMHESMKLFDSICNNKWFTETSIILFLNKKDLFEEKIKRSPLTICYPEYTGSNTYEEA 240 250 260 270 280 290 310 320 330 340 350 pF1KB6 ASYIQSKFEDLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF :.::: .:::::.:::::::::::::::::::::::::::::::::::::.:::. NP_006 AAYIQCQFEDLNRRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKECGLY 300 310 320 330 340 350 >>NP_001269546 (OMIM: 139360,192605) guanine nucleotide- (303 aa) initn: 2026 init1: 2026 opt: 2026 Z-score: 2455.2 bits: 462.6 E(85289): 5.2e-130 Smith-Waterman score: 2026; 100.0% identity (100.0% similar) in 303 aa overlap (53-355:1-303) 30 40 50 60 70 80 pF1KB6 LREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEDGYSEEECRQYRAVVYSNTIQSIM :::::::::::::::::::::::::::::: NP_001 MKIIHEDGYSEEECRQYRAVVYSNTIQSIM 10 20 30 90 100 110 120 130 140 pF1KB6 AIVKAMGNLQIDFADPSRADDARQLFALSCTAEEQGVLPDDLSGVIRRLWADHGVQACFG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AIVKAMGNLQIDFADPSRADDARQLFALSCTAEEQGVLPDDLSGVIRRLWADHGVQACFG 40 50 60 70 80 90 150 160 170 180 190 200 pF1KB6 RSREYQLNDSAAYYLNDLERIAQSDYIPTQQDVLRTRVKTTGIVETHFTFKDLHFKMFDV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RSREYQLNDSAAYYLNDLERIAQSDYIPTQQDVLRTRVKTTGIVETHFTFKDLHFKMFDV 100 110 120 130 140 150 210 220 230 240 250 260 pF1KB6 GGQRSERKKWIHCFEGVTAIIFCVALSAYDLVLAEDEEMNRMHESMKLFDSICNNKWFTD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GGQRSERKKWIHCFEGVTAIIFCVALSAYDLVLAEDEEMNRMHESMKLFDSICNNKWFTD 160 170 180 190 200 210 270 280 290 300 310 320 pF1KB6 TSIILFLNKKDLFEEKITHSPLTICFPEYTGANKYDEAASYIQSKFEDLNKRKDTKEIYT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TSIILFLNKKDLFEEKITHSPLTICFPEYTGANKYDEAASYIQSKFEDLNKRKDTKEIYT 220 230 240 250 260 270 330 340 350 pF1KB6 HFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF ::::::::::::::::::::::::::::::::: NP_001 HFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF 280 290 300 >>NP_001269547 (OMIM: 139360,192605) guanine nucleotide- (274 aa) initn: 1836 init1: 1836 opt: 1836 Z-score: 2225.9 bits: 420.0 E(85289): 3e-117 Smith-Waterman score: 1836; 100.0% identity (100.0% similar) in 274 aa overlap (82-355:1-274) 60 70 80 90 100 110 pF1KB6 QMKIIHEDGYSEEECRQYRAVVYSNTIQSIMAIVKAMGNLQIDFADPSRADDARQLFALS :::::::::::::::::::::::::::::: NP_001 MAIVKAMGNLQIDFADPSRADDARQLFALS 10 20 30 120 130 140 150 160 170 pF1KB6 CTAEEQGVLPDDLSGVIRRLWADHGVQACFGRSREYQLNDSAAYYLNDLERIAQSDYIPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CTAEEQGVLPDDLSGVIRRLWADHGVQACFGRSREYQLNDSAAYYLNDLERIAQSDYIPT 40 50 60 70 80 90 180 190 200 210 220 230 pF1KB6 QQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSAY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QQDVLRTRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSAY 100 110 120 130 140 150 240 250 260 270 280 290 pF1KB6 DLVLAEDEEMNRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKITHSPLTICFPEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DLVLAEDEEMNRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKITHSPLTICFPEY 160 170 180 190 200 210 300 310 320 330 340 350 pF1KB6 TGANKYDEAASYIQSKFEDLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TGANKYDEAASYIQSKFEDLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKD 220 230 240 250 260 270 pF1KB6 CGLF :::: NP_001 CGLF >>NP_001243343 (OMIM: 139310) guanine nucleotide-binding (302 aa) initn: 1468 init1: 1468 opt: 1770 Z-score: 2145.6 bits: 405.3 E(85289): 9e-113 Smith-Waterman score: 1770; 86.8% identity (95.0% similar) in 303 aa overlap (53-355:1-302) 30 40 50 60 70 80 pF1KB6 LREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEDGYSEEECRQYRAVVYSNTIQSIM :::::: :::::::.::.:::::::::::. NP_001 MKIIHEAGYSEEECKQYKAVVYSNTIQSII 10 20 30 90 100 110 120 130 140 pF1KB6 AIVKAMGNLQIDFADPSRADDARQLFALSCTAEEQGVLPDDLSGVIRRLWADHGVQACFG ::..::: :.:::.: .:::::::::.:. .::: : . .:.:::.::: : ::::::. NP_001 AIIRAMGRLKIDFGDSARADDARQLFVLAGAAEE-GFMTAELAGVIKRLWKDSGVQACFN 40 50 60 70 80 150 160 170 180 190 200 pF1KB6 RSREYQLNDSAAYYLNDLERIAQSDYIPTQQDVLRTRVKTTGIVETHFTFKDLHFKMFDV ::::::::::::::::::.:::: .::::::::::::::::::::::::::::::::::: NP_001 RSREYQLNDSAAYYLNDLDRIAQPNYIPTQQDVLRTRVKTTGIVETHFTFKDLHFKMFDV 90 100 110 120 130 140 210 220 230 240 250 260 pF1KB6 GGQRSERKKWIHCFEGVTAIIFCVALSAYDLVLAEDEEMNRMHESMKLFDSICNNKWFTD ::::::::::::::::::::::::::: :::::::::::::::::::::::::::::::: NP_001 GGQRSERKKWIHCFEGVTAIIFCVALSDYDLVLAEDEEMNRMHESMKLFDSICNNKWFTD 150 160 170 180 190 200 270 280 290 300 310 320 pF1KB6 TSIILFLNKKDLFEEKITHSPLTICFPEYTGANKYDEAASYIQSKFEDLNKRKDTKEIYT ::::::::::::::::: .::::::.:::.:.: :.:::.::: .::::::::::::::: NP_001 TSIILFLNKKDLFEEKIKKSPLTICYPEYAGSNTYEEAAAYIQCQFEDLNKRKDTKEIYT 210 220 230 240 250 260 330 340 350 pF1KB6 HFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF ::::::::::::::::::::::::::::::::: NP_001 HFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF 270 280 290 300 >>NP_001095856 (OMIM: 139395) guanine nucleotide-binding (354 aa) initn: 1222 init1: 1222 opt: 1697 Z-score: 2056.5 bits: 389.0 E(85289): 8.3e-108 Smith-Waterman score: 1697; 68.7% identity (90.7% similar) in 355 aa overlap (1-355:1-354) 10 20 30 40 50 60 pF1KB6 MGCTVSAEDKAAAERSKMIDKNLREDGEKAAREVKLLLLGAGESGKSTIVKQMKIIHEDG :: .:.:.: .:.::: ..:.:.::.:. :: ::::::::::::::::::::::::..: NP_001 MGSGISSESKESAKRSKELEKKLQEDAERDARTVKLLLLGAGESGKSTIVKQMKIIHKNG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 YSEEECRQYRAVVYSNTIQSIMAIVKAMGNLQIDFADPSRADDARQLFALSCTAEEQGVL :::.:: ...::.::::.:::.:::::: .: ::...: :.: :::.:.. : :. :. NP_001 YSEQECMEFKAVIYSNTLQSILAIVKAMTTLGIDYVNPRSAEDQRQLYAMANTLEDGGMT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 PDDLSGVIRRLWADHGVQACFGRSREYQLNDSAAYYLNDLERIAQSDYIPTQQDVLRTRV :. :. ::.::: : :.:::: :. :::::::::::::::.::. : :.:..::::..:: NP_001 PQ-LAEVIKRLWRDPGIQACFERASEYQLNDSAAYYLNDLDRITASGYVPNEQDVLHSRV 130 140 150 160 170 190 200 210 220 230 240 pF1KB6 KTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSAYDLVLAEDEE :::::.::.:.::::::.:::::::::::::::::::::: ::::.::::::.::.:::: NP_001 KTTGIIETQFSFKDLHFRMFDVGGQRSERKKWIHCFEGVTCIIFCAALSAYDMVLVEDEE 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB6 MNRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKITHSPLTICFPEYTGANKYDEA .::::::..::.::::.:.:. :::.:::::::.:.::.:. :.:::::::: : ...: NP_001 VNRMHESLHLFNSICNHKYFSTTSIVLFLNKKDIFQEKVTKVHLSICFPEYTGPNTFEDA 240 250 260 270 280 290 310 320 330 340 350 pF1KB6 ASYIQSKFEDLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKDCGLF ..::...: ::: .:. ::::.:.::::::.::.::::::::.:::.:::::::: NP_001 GNYIKNQFLDLNLKKEDKEIYSHMTCATDTQNVKFVFDAVTDIIIKENLKDCGLF 300 310 320 330 340 350 355 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 20:58:44 2016 done: Fri Nov 4 20:58:45 2016 Total Scan time: 7.360 Total Display time: 0.050 Function used was FASTA [36.3.4 Apr, 2011]