FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6476, 355 aa 1>>>pF1KB6476 355 - 355 aa - 355 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.8005+/-0.000536; mu= 5.1988+/- 0.033 mean_var=237.6441+/-51.987, 0's: 0 Z-trim(113.4): 314 B-trim: 37 in 1/59 Lambda= 0.083198 statistics sampled from 22343 (22768) to 22343 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.634), E-opt: 0.2 (0.267), width: 16 Scan time: 6.470 The best scores are: opt bits E(85289) XP_011520191 (OMIM: 603362) PREDICTED: endophilin- ( 355) 2321 292.1 1.2e-78 NP_001288038 (OMIM: 603362) endophilin-A3 isoform ( 355) 2321 292.1 1.2e-78 NP_001311112 (OMIM: 603362) endophilin-A3 isoform ( 355) 2321 292.1 1.2e-78 NP_003018 (OMIM: 603362) endophilin-A3 isoform a [ ( 347) 2162 273.1 6.7e-73 NP_001311113 (OMIM: 603362) endophilin-A3 isoform ( 312) 2028 256.9 4.3e-68 NP_001311115 (OMIM: 603362) endophilin-A3 isoform ( 312) 2028 256.9 4.3e-68 XP_016877975 (OMIM: 603362) PREDICTED: endophilin- ( 278) 1817 231.5 1.7e-60 NP_001311114 (OMIM: 603362) endophilin-A3 isoform ( 278) 1817 231.5 1.7e-60 NP_001288037 (OMIM: 603362) endophilin-A3 isoform ( 278) 1817 231.5 1.7e-60 NP_001311116 (OMIM: 603362) endophilin-A3 isoform ( 278) 1817 231.5 1.7e-60 NP_001311111 (OMIM: 603362) endophilin-A3 isoform ( 360) 1679 215.1 1.9e-55 NP_003017 (OMIM: 604465) endophilin-A1 [Homo sapie ( 352) 1532 197.4 3.9e-50 XP_011516307 (OMIM: 604465) PREDICTED: endophilin- ( 386) 1530 197.2 4.9e-50 XP_011520194 (OMIM: 603362) PREDICTED: endophilin- ( 217) 1403 181.7 1.3e-45 XP_011520193 (OMIM: 603362) PREDICTED: endophilin- ( 237) 1402 181.6 1.5e-45 NP_003016 (OMIM: 601768) endophilin-A2 isoform 1 [ ( 368) 1184 155.7 1.5e-37 XP_016882635 (OMIM: 601768) PREDICTED: endophilin- ( 358) 1182 155.4 1.8e-37 XP_011526485 (OMIM: 601768) PREDICTED: endophilin- ( 333) 1082 143.4 6.9e-34 NP_001186872 (OMIM: 601768) endophilin-A2 isoform ( 320) 708 98.5 2.2e-20 NP_001186873 (OMIM: 601768) endophilin-A2 isoform ( 304) 545 78.9 1.6e-14 NP_057093 (OMIM: 609287) endophilin-B1 isoform 1 [ ( 365) 300 49.6 1.3e-05 NP_001193580 (OMIM: 609287) endophilin-B1 isoform ( 394) 271 46.1 0.00015 XP_016856898 (OMIM: 609287) PREDICTED: endophilin- ( 235) 260 44.6 0.00027 XP_006710735 (OMIM: 609287) PREDICTED: endophilin- ( 402) 260 44.8 0.00039 XP_016856899 (OMIM: 609287) PREDICTED: endophilin- ( 219) 255 43.9 0.0004 NP_001273975 (OMIM: 609288) endophilin-B2 isoform ( 395) 258 44.6 0.00045 NP_064530 (OMIM: 609288) endophilin-B2 isoform b [ ( 395) 258 44.6 0.00045 XP_005252155 (OMIM: 609288) PREDICTED: endophilin- ( 400) 258 44.6 0.00046 NP_001193581 (OMIM: 609287) endophilin-B1 isoform ( 386) 256 44.3 0.00053 XP_011539840 (OMIM: 609287) PREDICTED: endophilin- ( 378) 255 44.2 0.00057 XP_006717254 (OMIM: 609288) PREDICTED: endophilin- ( 399) 251 43.7 0.00082 NP_001273974 (OMIM: 609288) endophilin-B2 isoform ( 404) 251 43.8 0.00083 XP_006717252 (OMIM: 609288) PREDICTED: endophilin- ( 424) 246 43.2 0.0013 XP_005252157 (OMIM: 609288) PREDICTED: endophilin- ( 379) 239 42.3 0.0021 XP_006717253 (OMIM: 609288) PREDICTED: endophilin- ( 423) 239 42.3 0.0023 XP_006717251 (OMIM: 609288) PREDICTED: endophilin- ( 428) 239 42.3 0.0023 NP_001139147 (OMIM: 616349) sorbin and SH3 domain- ( 492) 226 40.9 0.0075 XP_016864263 (OMIM: 616349) PREDICTED: sorbin and ( 564) 226 40.9 0.0082 XP_016864261 (OMIM: 616349) PREDICTED: sorbin and ( 619) 226 41.0 0.0087 XP_016864262 (OMIM: 616349) PREDICTED: sorbin and ( 619) 226 41.0 0.0087 XP_016864259 (OMIM: 616349) PREDICTED: sorbin and ( 627) 226 41.0 0.0088 XP_016864258 (OMIM: 616349) PREDICTED: sorbin and ( 635) 226 41.0 0.0089 XP_016864257 (OMIM: 616349) PREDICTED: sorbin and ( 636) 226 41.0 0.0089 XP_016864255 (OMIM: 616349) PREDICTED: sorbin and ( 642) 226 41.0 0.0089 XP_016864256 (OMIM: 616349) PREDICTED: sorbin and ( 642) 226 41.0 0.0089 NP_001139142 (OMIM: 616349) sorbin and SH3 domain- ( 644) 226 41.0 0.0089 XP_016864260 (OMIM: 616349) PREDICTED: sorbin and ( 645) 226 41.0 0.009 XP_016864253 (OMIM: 616349) PREDICTED: sorbin and ( 650) 226 41.0 0.009 XP_016864254 (OMIM: 616349) PREDICTED: sorbin and ( 650) 226 41.0 0.009 XP_005263370 (OMIM: 616349) PREDICTED: sorbin and ( 658) 226 41.0 0.0091 >>XP_011520191 (OMIM: 603362) PREDICTED: endophilin-A3 i (355 aa) initn: 2321 init1: 2321 opt: 2321 Z-score: 1532.8 bits: 292.1 E(85289): 1.2e-78 Smith-Waterman score: 2321; 100.0% identity (100.0% similar) in 355 aa overlap (1-355:1-355) 10 20 30 40 50 60 pF1KB6 MDGIFAGIICNQANRCLTWTSQQLFSEKISGAEGTKLDDEFLDMERKIDVTNKVVAEILS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MDGIFAGIICNQANRCLTWTSQQLFSEKISGAEGTKLDDEFLDMERKIDVTNKVVAEILS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 KTTEYLQPNPAYRAKLGMLNTVSKIRGQVKTTGYPQTEGLLGDCMLKYGKELGEDSTFGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KTTEYLQPNPAYRAKLGMLNTVSKIRGQVKTTGYPQTEGLLGDCMLKYGKELGEDSTFGN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 ALIEVGESMKLMAEVKDSLDINVKQTFIDPLQLLQDKDLKEIGHHLKKLEGRRLDYDYKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ALIEVGESMKLMAEVKDSLDINVKQTFIDPLQLLQDKDLKEIGHHLKKLEGRRLDYDYKK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 KRVGKIPDEEVRQAVEKFEESKELAERSMFNFLENDVEQVSQLAVFIEAALDYHRQSTEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 KRVGKIPDEEVRQAVEKFEESKELAERSMFNFLENDVEQVSQLAVFIEAALDYHRQSTEI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 LQELQSKLQMRISAASSVPRREYKPRPVKRSSSELNGVSTTSVVKTTGSNIPMDQPCCRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LQELQSKLQMRISAASSVPRREYKPRPVKRSSSELNGVSTTSVVKTTGSNIPMDQPCCRG 250 260 270 280 290 300 310 320 330 340 350 pF1KB6 LYDFEPENQGELGFKEGDIITLTNQIDENWYEGMIHGESGFFPINYVEVIVPLPQ ::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LYDFEPENQGELGFKEGDIITLTNQIDENWYEGMIHGESGFFPINYVEVIVPLPQ 310 320 330 340 350 >>NP_001288038 (OMIM: 603362) endophilin-A3 isoform c [H (355 aa) initn: 2321 init1: 2321 opt: 2321 Z-score: 1532.8 bits: 292.1 E(85289): 1.2e-78 Smith-Waterman score: 2321; 100.0% identity (100.0% similar) in 355 aa overlap (1-355:1-355) 10 20 30 40 50 60 pF1KB6 MDGIFAGIICNQANRCLTWTSQQLFSEKISGAEGTKLDDEFLDMERKIDVTNKVVAEILS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDGIFAGIICNQANRCLTWTSQQLFSEKISGAEGTKLDDEFLDMERKIDVTNKVVAEILS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 KTTEYLQPNPAYRAKLGMLNTVSKIRGQVKTTGYPQTEGLLGDCMLKYGKELGEDSTFGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KTTEYLQPNPAYRAKLGMLNTVSKIRGQVKTTGYPQTEGLLGDCMLKYGKELGEDSTFGN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 ALIEVGESMKLMAEVKDSLDINVKQTFIDPLQLLQDKDLKEIGHHLKKLEGRRLDYDYKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALIEVGESMKLMAEVKDSLDINVKQTFIDPLQLLQDKDLKEIGHHLKKLEGRRLDYDYKK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 KRVGKIPDEEVRQAVEKFEESKELAERSMFNFLENDVEQVSQLAVFIEAALDYHRQSTEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KRVGKIPDEEVRQAVEKFEESKELAERSMFNFLENDVEQVSQLAVFIEAALDYHRQSTEI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 LQELQSKLQMRISAASSVPRREYKPRPVKRSSSELNGVSTTSVVKTTGSNIPMDQPCCRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LQELQSKLQMRISAASSVPRREYKPRPVKRSSSELNGVSTTSVVKTTGSNIPMDQPCCRG 250 260 270 280 290 300 310 320 330 340 350 pF1KB6 LYDFEPENQGELGFKEGDIITLTNQIDENWYEGMIHGESGFFPINYVEVIVPLPQ ::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LYDFEPENQGELGFKEGDIITLTNQIDENWYEGMIHGESGFFPINYVEVIVPLPQ 310 320 330 340 350 >>NP_001311112 (OMIM: 603362) endophilin-A3 isoform c [H (355 aa) initn: 2321 init1: 2321 opt: 2321 Z-score: 1532.8 bits: 292.1 E(85289): 1.2e-78 Smith-Waterman score: 2321; 100.0% identity (100.0% similar) in 355 aa overlap (1-355:1-355) 10 20 30 40 50 60 pF1KB6 MDGIFAGIICNQANRCLTWTSQQLFSEKISGAEGTKLDDEFLDMERKIDVTNKVVAEILS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDGIFAGIICNQANRCLTWTSQQLFSEKISGAEGTKLDDEFLDMERKIDVTNKVVAEILS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 KTTEYLQPNPAYRAKLGMLNTVSKIRGQVKTTGYPQTEGLLGDCMLKYGKELGEDSTFGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KTTEYLQPNPAYRAKLGMLNTVSKIRGQVKTTGYPQTEGLLGDCMLKYGKELGEDSTFGN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 ALIEVGESMKLMAEVKDSLDINVKQTFIDPLQLLQDKDLKEIGHHLKKLEGRRLDYDYKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ALIEVGESMKLMAEVKDSLDINVKQTFIDPLQLLQDKDLKEIGHHLKKLEGRRLDYDYKK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 KRVGKIPDEEVRQAVEKFEESKELAERSMFNFLENDVEQVSQLAVFIEAALDYHRQSTEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KRVGKIPDEEVRQAVEKFEESKELAERSMFNFLENDVEQVSQLAVFIEAALDYHRQSTEI 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 LQELQSKLQMRISAASSVPRREYKPRPVKRSSSELNGVSTTSVVKTTGSNIPMDQPCCRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LQELQSKLQMRISAASSVPRREYKPRPVKRSSSELNGVSTTSVVKTTGSNIPMDQPCCRG 250 260 270 280 290 300 310 320 330 340 350 pF1KB6 LYDFEPENQGELGFKEGDIITLTNQIDENWYEGMIHGESGFFPINYVEVIVPLPQ ::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LYDFEPENQGELGFKEGDIITLTNQIDENWYEGMIHGESGFFPINYVEVIVPLPQ 310 320 330 340 350 >>NP_003018 (OMIM: 603362) endophilin-A3 isoform a [Homo (347 aa) initn: 2162 init1: 2162 opt: 2162 Z-score: 1429.8 bits: 273.1 E(85289): 6.7e-73 Smith-Waterman score: 2162; 99.4% identity (100.0% similar) in 335 aa overlap (21-355:13-347) 10 20 30 40 50 60 pF1KB6 MDGIFAGIICNQANRCLTWTSQQLFSEKISGAEGTKLDDEFLDMERKIDVTNKVVAEILS ..:::::::::::::::::::::::::::::::::::::: NP_003 MSVAGLKKQFHKASQLFSEKISGAEGTKLDDEFLDMERKIDVTNKVVAEILS 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 KTTEYLQPNPAYRAKLGMLNTVSKIRGQVKTTGYPQTEGLLGDCMLKYGKELGEDSTFGN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 KTTEYLQPNPAYRAKLGMLNTVSKIRGQVKTTGYPQTEGLLGDCMLKYGKELGEDSTFGN 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 ALIEVGESMKLMAEVKDSLDINVKQTFIDPLQLLQDKDLKEIGHHLKKLEGRRLDYDYKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 ALIEVGESMKLMAEVKDSLDINVKQTFIDPLQLLQDKDLKEIGHHLKKLEGRRLDYDYKK 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB6 KRVGKIPDEEVRQAVEKFEESKELAERSMFNFLENDVEQVSQLAVFIEAALDYHRQSTEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 KRVGKIPDEEVRQAVEKFEESKELAERSMFNFLENDVEQVSQLAVFIEAALDYHRQSTEI 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB6 LQELQSKLQMRISAASSVPRREYKPRPVKRSSSELNGVSTTSVVKTTGSNIPMDQPCCRG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 LQELQSKLQMRISAASSVPRREYKPRPVKRSSSELNGVSTTSVVKTTGSNIPMDQPCCRG 240 250 260 270 280 290 310 320 330 340 350 pF1KB6 LYDFEPENQGELGFKEGDIITLTNQIDENWYEGMIHGESGFFPINYVEVIVPLPQ ::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_003 LYDFEPENQGELGFKEGDIITLTNQIDENWYEGMIHGESGFFPINYVEVIVPLPQ 300 310 320 330 340 >>NP_001311113 (OMIM: 603362) endophilin-A3 isoform e [H (312 aa) initn: 2028 init1: 2028 opt: 2028 Z-score: 1343.4 bits: 256.9 E(85289): 4.3e-68 Smith-Waterman score: 2028; 100.0% identity (100.0% similar) in 312 aa overlap (44-355:1-312) 20 30 40 50 60 70 pF1KB6 NRCLTWTSQQLFSEKISGAEGTKLDDEFLDMERKIDVTNKVVAEILSKTTEYLQPNPAYR :::::::::::::::::::::::::::::: NP_001 MERKIDVTNKVVAEILSKTTEYLQPNPAYR 10 20 30 80 90 100 110 120 130 pF1KB6 AKLGMLNTVSKIRGQVKTTGYPQTEGLLGDCMLKYGKELGEDSTFGNALIEVGESMKLMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AKLGMLNTVSKIRGQVKTTGYPQTEGLLGDCMLKYGKELGEDSTFGNALIEVGESMKLMA 40 50 60 70 80 90 140 150 160 170 180 190 pF1KB6 EVKDSLDINVKQTFIDPLQLLQDKDLKEIGHHLKKLEGRRLDYDYKKKRVGKIPDEEVRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EVKDSLDINVKQTFIDPLQLLQDKDLKEIGHHLKKLEGRRLDYDYKKKRVGKIPDEEVRQ 100 110 120 130 140 150 200 210 220 230 240 250 pF1KB6 AVEKFEESKELAERSMFNFLENDVEQVSQLAVFIEAALDYHRQSTEILQELQSKLQMRIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AVEKFEESKELAERSMFNFLENDVEQVSQLAVFIEAALDYHRQSTEILQELQSKLQMRIS 160 170 180 190 200 210 260 270 280 290 300 310 pF1KB6 AASSVPRREYKPRPVKRSSSELNGVSTTSVVKTTGSNIPMDQPCCRGLYDFEPENQGELG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AASSVPRREYKPRPVKRSSSELNGVSTTSVVKTTGSNIPMDQPCCRGLYDFEPENQGELG 220 230 240 250 260 270 320 330 340 350 pF1KB6 FKEGDIITLTNQIDENWYEGMIHGESGFFPINYVEVIVPLPQ :::::::::::::::::::::::::::::::::::::::::: NP_001 FKEGDIITLTNQIDENWYEGMIHGESGFFPINYVEVIVPLPQ 280 290 300 310 >>NP_001311115 (OMIM: 603362) endophilin-A3 isoform e [H (312 aa) initn: 2028 init1: 2028 opt: 2028 Z-score: 1343.4 bits: 256.9 E(85289): 4.3e-68 Smith-Waterman score: 2028; 100.0% identity (100.0% similar) in 312 aa overlap (44-355:1-312) 20 30 40 50 60 70 pF1KB6 NRCLTWTSQQLFSEKISGAEGTKLDDEFLDMERKIDVTNKVVAEILSKTTEYLQPNPAYR :::::::::::::::::::::::::::::: NP_001 MERKIDVTNKVVAEILSKTTEYLQPNPAYR 10 20 30 80 90 100 110 120 130 pF1KB6 AKLGMLNTVSKIRGQVKTTGYPQTEGLLGDCMLKYGKELGEDSTFGNALIEVGESMKLMA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AKLGMLNTVSKIRGQVKTTGYPQTEGLLGDCMLKYGKELGEDSTFGNALIEVGESMKLMA 40 50 60 70 80 90 140 150 160 170 180 190 pF1KB6 EVKDSLDINVKQTFIDPLQLLQDKDLKEIGHHLKKLEGRRLDYDYKKKRVGKIPDEEVRQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EVKDSLDINVKQTFIDPLQLLQDKDLKEIGHHLKKLEGRRLDYDYKKKRVGKIPDEEVRQ 100 110 120 130 140 150 200 210 220 230 240 250 pF1KB6 AVEKFEESKELAERSMFNFLENDVEQVSQLAVFIEAALDYHRQSTEILQELQSKLQMRIS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AVEKFEESKELAERSMFNFLENDVEQVSQLAVFIEAALDYHRQSTEILQELQSKLQMRIS 160 170 180 190 200 210 260 270 280 290 300 310 pF1KB6 AASSVPRREYKPRPVKRSSSELNGVSTTSVVKTTGSNIPMDQPCCRGLYDFEPENQGELG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AASSVPRREYKPRPVKRSSSELNGVSTTSVVKTTGSNIPMDQPCCRGLYDFEPENQGELG 220 230 240 250 260 270 320 330 340 350 pF1KB6 FKEGDIITLTNQIDENWYEGMIHGESGFFPINYVEVIVPLPQ :::::::::::::::::::::::::::::::::::::::::: NP_001 FKEGDIITLTNQIDENWYEGMIHGESGFFPINYVEVIVPLPQ 280 290 300 310 >>XP_016877975 (OMIM: 603362) PREDICTED: endophilin-A3 i (278 aa) initn: 1817 init1: 1817 opt: 1817 Z-score: 1207.1 bits: 231.5 E(85289): 1.7e-60 Smith-Waterman score: 1817; 100.0% identity (100.0% similar) in 278 aa overlap (78-355:1-278) 50 60 70 80 90 100 pF1KB6 IDVTNKVVAEILSKTTEYLQPNPAYRAKLGMLNTVSKIRGQVKTTGYPQTEGLLGDCMLK :::::::::::::::::::::::::::::: XP_016 MLNTVSKIRGQVKTTGYPQTEGLLGDCMLK 10 20 30 110 120 130 140 150 160 pF1KB6 YGKELGEDSTFGNALIEVGESMKLMAEVKDSLDINVKQTFIDPLQLLQDKDLKEIGHHLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YGKELGEDSTFGNALIEVGESMKLMAEVKDSLDINVKQTFIDPLQLLQDKDLKEIGHHLK 40 50 60 70 80 90 170 180 190 200 210 220 pF1KB6 KLEGRRLDYDYKKKRVGKIPDEEVRQAVEKFEESKELAERSMFNFLENDVEQVSQLAVFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KLEGRRLDYDYKKKRVGKIPDEEVRQAVEKFEESKELAERSMFNFLENDVEQVSQLAVFI 100 110 120 130 140 150 230 240 250 260 270 280 pF1KB6 EAALDYHRQSTEILQELQSKLQMRISAASSVPRREYKPRPVKRSSSELNGVSTTSVVKTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EAALDYHRQSTEILQELQSKLQMRISAASSVPRREYKPRPVKRSSSELNGVSTTSVVKTT 160 170 180 190 200 210 290 300 310 320 330 340 pF1KB6 GSNIPMDQPCCRGLYDFEPENQGELGFKEGDIITLTNQIDENWYEGMIHGESGFFPINYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GSNIPMDQPCCRGLYDFEPENQGELGFKEGDIITLTNQIDENWYEGMIHGESGFFPINYV 220 230 240 250 260 270 350 pF1KB6 EVIVPLPQ :::::::: XP_016 EVIVPLPQ >>NP_001311114 (OMIM: 603362) endophilin-A3 isoform f [H (278 aa) initn: 1817 init1: 1817 opt: 1817 Z-score: 1207.1 bits: 231.5 E(85289): 1.7e-60 Smith-Waterman score: 1817; 100.0% identity (100.0% similar) in 278 aa overlap (78-355:1-278) 50 60 70 80 90 100 pF1KB6 IDVTNKVVAEILSKTTEYLQPNPAYRAKLGMLNTVSKIRGQVKTTGYPQTEGLLGDCMLK :::::::::::::::::::::::::::::: NP_001 MLNTVSKIRGQVKTTGYPQTEGLLGDCMLK 10 20 30 110 120 130 140 150 160 pF1KB6 YGKELGEDSTFGNALIEVGESMKLMAEVKDSLDINVKQTFIDPLQLLQDKDLKEIGHHLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YGKELGEDSTFGNALIEVGESMKLMAEVKDSLDINVKQTFIDPLQLLQDKDLKEIGHHLK 40 50 60 70 80 90 170 180 190 200 210 220 pF1KB6 KLEGRRLDYDYKKKRVGKIPDEEVRQAVEKFEESKELAERSMFNFLENDVEQVSQLAVFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KLEGRRLDYDYKKKRVGKIPDEEVRQAVEKFEESKELAERSMFNFLENDVEQVSQLAVFI 100 110 120 130 140 150 230 240 250 260 270 280 pF1KB6 EAALDYHRQSTEILQELQSKLQMRISAASSVPRREYKPRPVKRSSSELNGVSTTSVVKTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EAALDYHRQSTEILQELQSKLQMRISAASSVPRREYKPRPVKRSSSELNGVSTTSVVKTT 160 170 180 190 200 210 290 300 310 320 330 340 pF1KB6 GSNIPMDQPCCRGLYDFEPENQGELGFKEGDIITLTNQIDENWYEGMIHGESGFFPINYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GSNIPMDQPCCRGLYDFEPENQGELGFKEGDIITLTNQIDENWYEGMIHGESGFFPINYV 220 230 240 250 260 270 350 pF1KB6 EVIVPLPQ :::::::: NP_001 EVIVPLPQ >>NP_001288037 (OMIM: 603362) endophilin-A3 isoform b [H (278 aa) initn: 1817 init1: 1817 opt: 1817 Z-score: 1207.1 bits: 231.5 E(85289): 1.7e-60 Smith-Waterman score: 1817; 100.0% identity (100.0% similar) in 278 aa overlap (78-355:1-278) 50 60 70 80 90 100 pF1KB6 IDVTNKVVAEILSKTTEYLQPNPAYRAKLGMLNTVSKIRGQVKTTGYPQTEGLLGDCMLK :::::::::::::::::::::::::::::: NP_001 MLNTVSKIRGQVKTTGYPQTEGLLGDCMLK 10 20 30 110 120 130 140 150 160 pF1KB6 YGKELGEDSTFGNALIEVGESMKLMAEVKDSLDINVKQTFIDPLQLLQDKDLKEIGHHLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YGKELGEDSTFGNALIEVGESMKLMAEVKDSLDINVKQTFIDPLQLLQDKDLKEIGHHLK 40 50 60 70 80 90 170 180 190 200 210 220 pF1KB6 KLEGRRLDYDYKKKRVGKIPDEEVRQAVEKFEESKELAERSMFNFLENDVEQVSQLAVFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KLEGRRLDYDYKKKRVGKIPDEEVRQAVEKFEESKELAERSMFNFLENDVEQVSQLAVFI 100 110 120 130 140 150 230 240 250 260 270 280 pF1KB6 EAALDYHRQSTEILQELQSKLQMRISAASSVPRREYKPRPVKRSSSELNGVSTTSVVKTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EAALDYHRQSTEILQELQSKLQMRISAASSVPRREYKPRPVKRSSSELNGVSTTSVVKTT 160 170 180 190 200 210 290 300 310 320 330 340 pF1KB6 GSNIPMDQPCCRGLYDFEPENQGELGFKEGDIITLTNQIDENWYEGMIHGESGFFPINYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GSNIPMDQPCCRGLYDFEPENQGELGFKEGDIITLTNQIDENWYEGMIHGESGFFPINYV 220 230 240 250 260 270 350 pF1KB6 EVIVPLPQ :::::::: NP_001 EVIVPLPQ >>NP_001311116 (OMIM: 603362) endophilin-A3 isoform f [H (278 aa) initn: 1817 init1: 1817 opt: 1817 Z-score: 1207.1 bits: 231.5 E(85289): 1.7e-60 Smith-Waterman score: 1817; 100.0% identity (100.0% similar) in 278 aa overlap (78-355:1-278) 50 60 70 80 90 100 pF1KB6 IDVTNKVVAEILSKTTEYLQPNPAYRAKLGMLNTVSKIRGQVKTTGYPQTEGLLGDCMLK :::::::::::::::::::::::::::::: NP_001 MLNTVSKIRGQVKTTGYPQTEGLLGDCMLK 10 20 30 110 120 130 140 150 160 pF1KB6 YGKELGEDSTFGNALIEVGESMKLMAEVKDSLDINVKQTFIDPLQLLQDKDLKEIGHHLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YGKELGEDSTFGNALIEVGESMKLMAEVKDSLDINVKQTFIDPLQLLQDKDLKEIGHHLK 40 50 60 70 80 90 170 180 190 200 210 220 pF1KB6 KLEGRRLDYDYKKKRVGKIPDEEVRQAVEKFEESKELAERSMFNFLENDVEQVSQLAVFI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KLEGRRLDYDYKKKRVGKIPDEEVRQAVEKFEESKELAERSMFNFLENDVEQVSQLAVFI 100 110 120 130 140 150 230 240 250 260 270 280 pF1KB6 EAALDYHRQSTEILQELQSKLQMRISAASSVPRREYKPRPVKRSSSELNGVSTTSVVKTT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EAALDYHRQSTEILQELQSKLQMRISAASSVPRREYKPRPVKRSSSELNGVSTTSVVKTT 160 170 180 190 200 210 290 300 310 320 330 340 pF1KB6 GSNIPMDQPCCRGLYDFEPENQGELGFKEGDIITLTNQIDENWYEGMIHGESGFFPINYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GSNIPMDQPCCRGLYDFEPENQGELGFKEGDIITLTNQIDENWYEGMIHGESGFFPINYV 220 230 240 250 260 270 350 pF1KB6 EVIVPLPQ :::::::: NP_001 EVIVPLPQ 355 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 16:26:14 2016 done: Fri Nov 4 16:26:15 2016 Total Scan time: 6.470 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]