FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6477, 326 aa 1>>>pF1KB6477 326 - 326 aa - 326 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.4890+/-0.000799; mu= 7.0316+/- 0.048 mean_var=141.7295+/-27.743, 0's: 0 Z-trim(112.4): 20 B-trim: 14 in 1/52 Lambda= 0.107732 statistics sampled from 13166 (13181) to 13166 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.76), E-opt: 0.2 (0.405), width: 16 Scan time: 2.630 The best scores are: opt bits E(32554) CCDS13301.1 RPRD1B gene_id:58490|Hs108|chr20 ( 326) 2082 334.6 6.5e-92 CCDS77178.1 RPRD1A gene_id:55197|Hs108|chr18 ( 276) 729 124.3 1.1e-28 CCDS11917.1 RPRD1A gene_id:55197|Hs108|chr18 ( 312) 680 116.7 2.5e-26 CCDS44216.1 RPRD2 gene_id:23248|Hs108|chr1 (1461) 373 69.4 2e-11 >>CCDS13301.1 RPRD1B gene_id:58490|Hs108|chr20 (326 aa) initn: 2082 init1: 2082 opt: 2082 Z-score: 1763.6 bits: 334.6 E(32554): 6.5e-92 Smith-Waterman score: 2082; 100.0% identity (100.0% similar) in 326 aa overlap (1-326:1-326) 10 20 30 40 50 60 pF1KB6 MSSFSESALEKKLSELSNSQQSVQTLSLWLIHHRKHAGPIVSVWHRELRKAKSNRKLTFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 MSSFSESALEKKLSELSNSQQSVQTLSLWLIHHRKHAGPIVSVWHRELRKAKSNRKLTFL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 YLANDVIQNSKRKGPEFTREFESVLVDAFSHVAREADEGCKKPLERLLNIWQERSVYGGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 YLANDVIQNSKRKGPEFTREFESVLVDAFSHVAREADEGCKKPLERLLNIWQERSVYGGE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 FIQQLKLSMEDSKSPPPKATEEKKSLKRTFQQIQEEEDDDYPGSYSPQDPSAGPLLTEEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 FIQQLKLSMEDSKSPPPKATEEKKSLKRTFQQIQEEEDDDYPGSYSPQDPSAGPLLTEEL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 IKALQDLENAASGDATVRQKIASLPQEVQDVSLLEKITDKEAAERLSKTVDEACLLLAEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 IKALQDLENAASGDATVRQKIASLPQEVQDVSLLEKITDKEAAERLSKTVDEACLLLAEY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 NGRLAAELEDRRQLARMLVEYTQNQKDVLSEKEKKLEEYKQKLARVTQVRKELKSHIQSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS13 NGRLAAELEDRRQLARMLVEYTQNQKDVLSEKEKKLEEYKQKLARVTQVRKELKSHIQSL 250 260 270 280 290 300 310 320 pF1KB6 PDLSLLPNVTGGLAPLPSAGDLFSTD :::::::::::::::::::::::::: CCDS13 PDLSLLPNVTGGLAPLPSAGDLFSTD 310 320 >>CCDS77178.1 RPRD1A gene_id:55197|Hs108|chr18 (276 aa) initn: 1078 init1: 657 opt: 729 Z-score: 628.1 bits: 124.3 E(32554): 1.1e-28 Smith-Waterman score: 1053; 61.2% identity (84.1% similar) in 276 aa overlap (51-326:15-276) 30 40 50 60 70 80 pF1KB6 QSVQTLSLWLIHHRKHAGPIVSVWHRELRKAKSNRKLTFLYLANDVIQNSKRKGPEFTRE .: :::::::::::::::::::::::::.. CCDS77 MRNSNWRFCQTGIYSKPNRKLTFLYLANDVIQNSKRKGPEFTKD 10 20 30 40 90 100 110 120 130 140 pF1KB6 FESVLVDAFSHVAREADEGCKKPLERLLNIWQERSVYGGEFIQQLKLSMEDSKSPPPKAT : :.:.::.::. :.::.::: : :.:.::.::::: .. ..::: .. .:.: CCDS77 FAPVIVEAFKHVSSETDESCKKHLGRVLSIWEERSVYENDVLEQLKQALYGDKKPR---- 50 60 70 80 90 100 150 160 170 180 190 200 pF1KB6 EEKKSLKRTFQQIQEEEDDDYPGSYSPQDPSAGPLLTEELIKALQDLENAASGDATVRQK :::..::. .:... . ::..: : : .:..:::::::::::::.:.:. CCDS77 ------KRTYEQIKVDENENCSSLGSPSEP---PQ-TLDLVRALQDLENAASGDAAVHQR 110 120 130 140 150 210 220 230 240 250 260 pF1KB6 IASLPQEVQDVSLLEKITDKEAAERLSKTVDEACLLLAEYNGRLAAELEDRRQLARMLVE ::::: :::.::::.::::::..::::: :..::.:::.::::::::..::.::.:::.. CCDS77 IASLPVEVQEVSLLDKITDKESGERLSKMVEDACMLLADYNGRLAAEIDDRKQLTRMLAD 160 170 180 190 200 210 270 280 290 300 310 320 pF1KB6 YTQNQKDVLSEKEKKLEEYKQKLARVTQVRKELKSHIQSLPDLSLLPNVTGGLAPLPSAG . . ::..:.:::.::::::.:::::. :::::.:.:::::::: ::::::. :: :: CCDS77 FLRCQKEALAEKEHKLEEYKRKLARVSLVRKELRSRIQSLPDLSRLPNVTGSHMHLPFAG 220 230 240 250 260 270 pF1KB6 DLFSTD :..: : CCDS77 DIYSED >>CCDS11917.1 RPRD1A gene_id:55197|Hs108|chr18 (312 aa) initn: 1371 init1: 668 opt: 680 Z-score: 586.2 bits: 116.7 E(32554): 2.5e-26 Smith-Waterman score: 1346; 65.6% identity (86.2% similar) in 326 aa overlap (1-326:1-312) 10 20 30 40 50 60 pF1KB6 MSSFSESALEKKLSELSNSQQSVQTLSLWLIHHRKHAGPIVSVWHRELRKAKSNRKLTFL ::.:::.:::::::::::::::::::::::::::::. :::.::.::::::: ::::::: CCDS11 MSAFSEAALEKKLSELSNSQQSVQTLSLWLIHHRKHSRPIVTVWERELRKAKPNRKLTFL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 YLANDVIQNSKRKGPEFTREFESVLVDAFSHVAREADEGCKKPLERLLNIWQERSVYGGE ::::::::::::::::::..: :.:.::.::. :.::.::: : :.:.::.::::: .. CCDS11 YLANDVIQNSKRKGPEFTKDFAPVIVEAFKHVSSETDESCKKHLGRVLSIWEERSVYEND 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 FIQQLKLSMEDSKSPPPKATEEKKSLKRTFQQIQEEEDDDYPGSYSPQDPSAGPLLTEEL ..::: .. .:.: :::..::. .:... . ::..: : : .: CCDS11 VLEQLKQALYGDKKPR----------KRTYEQIKVDENENCSSLGSPSEP---PQ-TLDL 130 140 150 160 190 200 210 220 230 240 pF1KB6 IKALQDLENAASGDATVRQKIASLPQEVQDVSLLEKITDKEAAERLSKTVDEACLLLAEY ..:::::::::::::.:.:.::::: :::.::::.::::::..::::: :..::.:::.: CCDS11 VRALQDLENAASGDAAVHQRIASLPVEVQEVSLLDKITDKESGERLSKMVEDACMLLADY 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB6 NGRLAAELEDRRQLARMLVEYTQNQKDVLSEKEKKLEEYKQKLARVTQVRKELKSHIQSL :::::::..::.::.:::... . ::..:.:::.::::::.:::::. :::::.:.:::: CCDS11 NGRLAAEIDDRKQLTRMLADFLRCQKEALAEKEHKLEEYKRKLARVSLVRKELRSRIQSL 230 240 250 260 270 280 310 320 pF1KB6 PDLSLLPNVTGGLAPLPSAGDLFSTD :::: ::::::. :: :::..: : CCDS11 PDLSRLPNVTGSHMHLPFAGDIYSED 290 300 310 >>CCDS44216.1 RPRD2 gene_id:23248|Hs108|chr1 (1461 aa) initn: 346 init1: 218 opt: 373 Z-score: 318.6 bits: 69.4 E(32554): 2e-11 Smith-Waterman score: 375; 27.0% identity (61.5% similar) in 322 aa overlap (6-321:24-335) 10 20 30 40 pF1KB6 MSSFSESALEKKLSELSNSQQSVQTLSLWLIHHRKHAGPIVS ::.:..:.. ..:...:.: :: : :...:: . :: CCDS44 MAAGGGGGSSKASSSSASSAGALESSLDRKFQSVTNTMESIQGLSSWCIENKKHHSTIVY 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB6 VWHRELRKAKSNRKLTFLYLANDVIQNSKRKGPEFTRE-FESVLVDAFSHVAREADEGCK : . ::.. ..:...::::::::: :::. . :: : .:: .: . : : . . CCDS44 HWMKWLRRSAYPHRLNLFYLANDVIQNCKRKNAIIFRESFADVLPEAAALVK---DPSVS 70 80 90 100 110 110 120 130 140 150 160 pF1KB6 KPLERLLNIWQERSVYGGEFIQQLKLSMEDSKSPPPKATEEKKSLKRTFQQIQEEEDDDY : .::...::..:.:: :.: :. .. . . .:.::..... ... CCDS44 KSVERIFKIWEDRNVYPEEMIVALREALSTT-------FKTQKQLKENLNKQPNKQWKKS 120 130 140 150 160 170 170 180 190 200 210 pF1KB6 PGSYSPQDPSAGPLLTEELIKALQD---LENAASGDATVRQK-IASLPQEVQDVSLLEKI : .:. . ...: .:: . : . . . ...: .... .: .. :. . CCDS44 QTSTNPKAALKSKIVAEFRSQALIEELLLYKRSEDQIELKEKQLSTMRVDVCSTETLKCL 180 190 200 210 220 230 220 230 240 250 260 270 pF1KB6 TDKEAAERLSKTVDEACLLLAEYNGRLAAELEDRRQLARMLVEYTQNQKDVLSEKEKKLE :: .....:: .:: : :. . : .... .:.. : . . .: . . CCDS44 KDKTGGKKFSKEFEEASSKLEEFVNGLDKQVKNGPSLTEALENAGIFYEAQYKEVKVVAN 240 250 260 270 280 290 280 290 300 310 320 pF1KB6 EYKQKLARVTQVRKELKSHIQSLPDLSLLPNVTGGL-APLPSAGDLFSTD :: ::....:.: . ..::: : . .. :: :.... CCDS44 AYKTFANRVNNLKKKLDQLKSTLPDPEESPVPSPSMDAPSPTGSESPFQGMGGEESQSPT 300 310 320 330 340 350 CCDS44 MESEKSATPEPVTDNRDVEDMELSDVEDDGSKIIVEDRKEKPAEKSAVSTSVPTKPTENI 360 370 380 390 400 410 326 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 20:59:14 2016 done: Fri Nov 4 20:59:15 2016 Total Scan time: 2.630 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]