FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6477, 326 aa 1>>>pF1KB6477 326 - 326 aa - 326 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.5787+/-0.000331; mu= 6.6963+/- 0.021 mean_var=158.5098+/-31.226, 0's: 0 Z-trim(120.0): 38 B-trim: 51 in 1/54 Lambda= 0.101870 statistics sampled from 34595 (34637) to 34595 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.763), E-opt: 0.2 (0.406), width: 16 Scan time: 7.730 The best scores are: opt bits E(85289) NP_067038 (OMIM: 614694) regulation of nuclear pre ( 326) 2082 317.4 2.6e-86 XP_005260534 (OMIM: 614694) PREDICTED: regulation ( 285) 1770 271.5 1.5e-72 XP_016883479 (OMIM: 614694) PREDICTED: regulation ( 323) 1770 271.5 1.6e-72 XP_011527256 (OMIM: 614694) PREDICTED: regulation ( 323) 1770 271.5 1.6e-72 XP_005260537 (OMIM: 614694) PREDICTED: regulation ( 193) 1176 184.1 2.1e-46 XP_016883480 (OMIM: 614694) PREDICTED: regulation ( 218) 1176 184.1 2.3e-46 XP_011524351 (OMIM: 610347) PREDICTED: regulation ( 276) 729 118.5 1.7e-26 XP_011524352 (OMIM: 610347) PREDICTED: regulation ( 276) 729 118.5 1.7e-26 NP_001290340 (OMIM: 610347) regulation of nuclear ( 276) 729 118.5 1.7e-26 NP_001290341 (OMIM: 610347) regulation of nuclear ( 276) 729 118.5 1.7e-26 XP_011524350 (OMIM: 610347) PREDICTED: regulation ( 312) 680 111.3 2.7e-24 NP_060640 (OMIM: 610347) regulation of nuclear pre ( 312) 680 111.3 2.7e-24 NP_001290342 (OMIM: 610347) regulation of nuclear ( 289) 668 109.5 8.5e-24 XP_016881297 (OMIM: 610347) PREDICTED: regulation ( 253) 511 86.4 6.8e-17 XP_005245090 (OMIM: 614695) PREDICTED: regulation ( 706) 373 66.5 1.9e-10 XP_016856254 (OMIM: 614695) PREDICTED: regulation ( 893) 373 66.6 2.3e-10 XP_006711303 (OMIM: 614695) PREDICTED: regulation ( 960) 373 66.6 2.4e-10 XP_011507646 (OMIM: 614695) PREDICTED: regulation (1394) 373 66.7 3.2e-10 NP_056018 (OMIM: 614695) regulation of nuclear pre (1461) 373 66.7 3.4e-10 XP_016856256 (OMIM: 614695) PREDICTED: regulation ( 613) 308 56.9 1.3e-07 XP_016856255 (OMIM: 614695) PREDICTED: regulation ( 680) 308 56.9 1.4e-07 NP_001284602 (OMIM: 614695) regulation of nuclear ( 934) 308 57.0 1.8e-07 XP_016856252 (OMIM: 614695) PREDICTED: regulation (1368) 308 57.1 2.4e-07 NP_001284603 (OMIM: 614695) regulation of nuclear (1435) 308 57.2 2.5e-07 >>NP_067038 (OMIM: 614694) regulation of nuclear pre-mRN (326 aa) initn: 2082 init1: 2082 opt: 2082 Z-score: 1670.6 bits: 317.4 E(85289): 2.6e-86 Smith-Waterman score: 2082; 100.0% identity (100.0% similar) in 326 aa overlap (1-326:1-326) 10 20 30 40 50 60 pF1KB6 MSSFSESALEKKLSELSNSQQSVQTLSLWLIHHRKHAGPIVSVWHRELRKAKSNRKLTFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_067 MSSFSESALEKKLSELSNSQQSVQTLSLWLIHHRKHAGPIVSVWHRELRKAKSNRKLTFL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 YLANDVIQNSKRKGPEFTREFESVLVDAFSHVAREADEGCKKPLERLLNIWQERSVYGGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_067 YLANDVIQNSKRKGPEFTREFESVLVDAFSHVAREADEGCKKPLERLLNIWQERSVYGGE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 FIQQLKLSMEDSKSPPPKATEEKKSLKRTFQQIQEEEDDDYPGSYSPQDPSAGPLLTEEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_067 FIQQLKLSMEDSKSPPPKATEEKKSLKRTFQQIQEEEDDDYPGSYSPQDPSAGPLLTEEL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 IKALQDLENAASGDATVRQKIASLPQEVQDVSLLEKITDKEAAERLSKTVDEACLLLAEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_067 IKALQDLENAASGDATVRQKIASLPQEVQDVSLLEKITDKEAAERLSKTVDEACLLLAEY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 NGRLAAELEDRRQLARMLVEYTQNQKDVLSEKEKKLEEYKQKLARVTQVRKELKSHIQSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_067 NGRLAAELEDRRQLARMLVEYTQNQKDVLSEKEKKLEEYKQKLARVTQVRKELKSHIQSL 250 260 270 280 290 300 310 320 pF1KB6 PDLSLLPNVTGGLAPLPSAGDLFSTD :::::::::::::::::::::::::: NP_067 PDLSLLPNVTGGLAPLPSAGDLFSTD 310 320 >>XP_005260534 (OMIM: 614694) PREDICTED: regulation of n (285 aa) initn: 1770 init1: 1770 opt: 1770 Z-score: 1423.6 bits: 271.5 E(85289): 1.5e-72 Smith-Waterman score: 1770; 100.0% identity (100.0% similar) in 277 aa overlap (1-277:1-277) 10 20 30 40 50 60 pF1KB6 MSSFSESALEKKLSELSNSQQSVQTLSLWLIHHRKHAGPIVSVWHRELRKAKSNRKLTFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MSSFSESALEKKLSELSNSQQSVQTLSLWLIHHRKHAGPIVSVWHRELRKAKSNRKLTFL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 YLANDVIQNSKRKGPEFTREFESVLVDAFSHVAREADEGCKKPLERLLNIWQERSVYGGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 YLANDVIQNSKRKGPEFTREFESVLVDAFSHVAREADEGCKKPLERLLNIWQERSVYGGE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 FIQQLKLSMEDSKSPPPKATEEKKSLKRTFQQIQEEEDDDYPGSYSPQDPSAGPLLTEEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 FIQQLKLSMEDSKSPPPKATEEKKSLKRTFQQIQEEEDDDYPGSYSPQDPSAGPLLTEEL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 IKALQDLENAASGDATVRQKIASLPQEVQDVSLLEKITDKEAAERLSKTVDEACLLLAEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 IKALQDLENAASGDATVRQKIASLPQEVQDVSLLEKITDKEAAERLSKTVDEACLLLAEY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 NGRLAAELEDRRQLARMLVEYTQNQKDVLSEKEKKLEEYKQKLARVTQVRKELKSHIQSL ::::::::::::::::::::::::::::::::::::: XP_005 NGRLAAELEDRRQLARMLVEYTQNQKDVLSEKEKKLEGVMIDFGL 250 260 270 280 310 320 pF1KB6 PDLSLLPNVTGGLAPLPSAGDLFSTD >>XP_016883479 (OMIM: 614694) PREDICTED: regulation of n (323 aa) initn: 1770 init1: 1770 opt: 1770 Z-score: 1422.8 bits: 271.5 E(85289): 1.6e-72 Smith-Waterman score: 1770; 100.0% identity (100.0% similar) in 277 aa overlap (1-277:1-277) 10 20 30 40 50 60 pF1KB6 MSSFSESALEKKLSELSNSQQSVQTLSLWLIHHRKHAGPIVSVWHRELRKAKSNRKLTFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSSFSESALEKKLSELSNSQQSVQTLSLWLIHHRKHAGPIVSVWHRELRKAKSNRKLTFL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 YLANDVIQNSKRKGPEFTREFESVLVDAFSHVAREADEGCKKPLERLLNIWQERSVYGGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YLANDVIQNSKRKGPEFTREFESVLVDAFSHVAREADEGCKKPLERLLNIWQERSVYGGE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 FIQQLKLSMEDSKSPPPKATEEKKSLKRTFQQIQEEEDDDYPGSYSPQDPSAGPLLTEEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 FIQQLKLSMEDSKSPPPKATEEKKSLKRTFQQIQEEEDDDYPGSYSPQDPSAGPLLTEEL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 IKALQDLENAASGDATVRQKIASLPQEVQDVSLLEKITDKEAAERLSKTVDEACLLLAEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IKALQDLENAASGDATVRQKIASLPQEVQDVSLLEKITDKEAAERLSKTVDEACLLLAEY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 NGRLAAELEDRRQLARMLVEYTQNQKDVLSEKEKKLEEYKQKLARVTQVRKELKSHIQSL ::::::::::::::::::::::::::::::::::::: XP_016 NGRLAAELEDRRQLARMLVEYTQNQKDVLSEKEKKLEIWLIHSAHVLGAYCLLDTAEPGG 250 260 270 280 290 300 310 320 pF1KB6 PDLSLLPNVTGGLAPLPSAGDLFSTD XP_016 CWGKQMGLVLASRSLLVKCGSHC 310 320 >>XP_011527256 (OMIM: 614694) PREDICTED: regulation of n (323 aa) initn: 1770 init1: 1770 opt: 1770 Z-score: 1422.8 bits: 271.5 E(85289): 1.6e-72 Smith-Waterman score: 1770; 100.0% identity (100.0% similar) in 277 aa overlap (1-277:1-277) 10 20 30 40 50 60 pF1KB6 MSSFSESALEKKLSELSNSQQSVQTLSLWLIHHRKHAGPIVSVWHRELRKAKSNRKLTFL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSSFSESALEKKLSELSNSQQSVQTLSLWLIHHRKHAGPIVSVWHRELRKAKSNRKLTFL 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 YLANDVIQNSKRKGPEFTREFESVLVDAFSHVAREADEGCKKPLERLLNIWQERSVYGGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 YLANDVIQNSKRKGPEFTREFESVLVDAFSHVAREADEGCKKPLERLLNIWQERSVYGGE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 FIQQLKLSMEDSKSPPPKATEEKKSLKRTFQQIQEEEDDDYPGSYSPQDPSAGPLLTEEL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 FIQQLKLSMEDSKSPPPKATEEKKSLKRTFQQIQEEEDDDYPGSYSPQDPSAGPLLTEEL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 IKALQDLENAASGDATVRQKIASLPQEVQDVSLLEKITDKEAAERLSKTVDEACLLLAEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 IKALQDLENAASGDATVRQKIASLPQEVQDVSLLEKITDKEAAERLSKTVDEACLLLAEY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 NGRLAAELEDRRQLARMLVEYTQNQKDVLSEKEKKLEEYKQKLARVTQVRKELKSHIQSL ::::::::::::::::::::::::::::::::::::: XP_011 NGRLAAELEDRRQLARMLVEYTQNQKDVLSEKEKKLEIWLIHSAHVLGAYCLLDTAEPGG 250 260 270 280 290 300 310 320 pF1KB6 PDLSLLPNVTGGLAPLPSAGDLFSTD XP_011 CWGKQMGLVLASRSLLVKCGSHC 310 320 >>XP_005260537 (OMIM: 614694) PREDICTED: regulation of n (193 aa) initn: 1176 init1: 1176 opt: 1176 Z-score: 954.1 bits: 184.1 E(85289): 2.1e-46 Smith-Waterman score: 1176; 100.0% identity (100.0% similar) in 188 aa overlap (139-326:6-193) 110 120 130 140 150 160 pF1KB6 NIWQERSVYGGEFIQQLKLSMEDSKSPPPKATEEKKSLKRTFQQIQEEEDDDYPGSYSPQ :::::::::::::::::::::::::::::: XP_005 MIMNDATEEKKSLKRTFQQIQEEEDDDYPGSYSPQ 10 20 30 170 180 190 200 210 220 pF1KB6 DPSAGPLLTEELIKALQDLENAASGDATVRQKIASLPQEVQDVSLLEKITDKEAAERLSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DPSAGPLLTEELIKALQDLENAASGDATVRQKIASLPQEVQDVSLLEKITDKEAAERLSK 40 50 60 70 80 90 230 240 250 260 270 280 pF1KB6 TVDEACLLLAEYNGRLAAELEDRRQLARMLVEYTQNQKDVLSEKEKKLEEYKQKLARVTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 TVDEACLLLAEYNGRLAAELEDRRQLARMLVEYTQNQKDVLSEKEKKLEEYKQKLARVTQ 100 110 120 130 140 150 290 300 310 320 pF1KB6 VRKELKSHIQSLPDLSLLPNVTGGLAPLPSAGDLFSTD :::::::::::::::::::::::::::::::::::::: XP_005 VRKELKSHIQSLPDLSLLPNVTGGLAPLPSAGDLFSTD 160 170 180 190 >>XP_016883480 (OMIM: 614694) PREDICTED: regulation of n (218 aa) initn: 1197 init1: 1176 opt: 1176 Z-score: 953.4 bits: 184.1 E(85289): 2.3e-46 Smith-Waterman score: 1176; 100.0% identity (100.0% similar) in 188 aa overlap (139-326:31-218) 110 120 130 140 150 160 pF1KB6 NIWQERSVYGGEFIQQLKLSMEDSKSPPPKATEEKKSLKRTFQQIQEEEDDDYPGSYSPQ :::::::::::::::::::::::::::::: XP_016 MMSSKTVKGKDLNSLENLNLSLWMLFLMLPATEEKKSLKRTFQQIQEEEDDDYPGSYSPQ 10 20 30 40 50 60 170 180 190 200 210 220 pF1KB6 DPSAGPLLTEELIKALQDLENAASGDATVRQKIASLPQEVQDVSLLEKITDKEAAERLSK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DPSAGPLLTEELIKALQDLENAASGDATVRQKIASLPQEVQDVSLLEKITDKEAAERLSK 70 80 90 100 110 120 230 240 250 260 270 280 pF1KB6 TVDEACLLLAEYNGRLAAELEDRRQLARMLVEYTQNQKDVLSEKEKKLEEYKQKLARVTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TVDEACLLLAEYNGRLAAELEDRRQLARMLVEYTQNQKDVLSEKEKKLEEYKQKLARVTQ 130 140 150 160 170 180 290 300 310 320 pF1KB6 VRKELKSHIQSLPDLSLLPNVTGGLAPLPSAGDLFSTD :::::::::::::::::::::::::::::::::::::: XP_016 VRKELKSHIQSLPDLSLLPNVTGGLAPLPSAGDLFSTD 190 200 210 >>XP_011524351 (OMIM: 610347) PREDICTED: regulation of n (276 aa) initn: 1078 init1: 657 opt: 729 Z-score: 596.9 bits: 118.5 E(85289): 1.7e-26 Smith-Waterman score: 1053; 61.2% identity (84.1% similar) in 276 aa overlap (51-326:15-276) 30 40 50 60 70 80 pF1KB6 QSVQTLSLWLIHHRKHAGPIVSVWHRELRKAKSNRKLTFLYLANDVIQNSKRKGPEFTRE .: :::::::::::::::::::::::::.. XP_011 MRNSNWRFCQTGIYSKPNRKLTFLYLANDVIQNSKRKGPEFTKD 10 20 30 40 90 100 110 120 130 140 pF1KB6 FESVLVDAFSHVAREADEGCKKPLERLLNIWQERSVYGGEFIQQLKLSMEDSKSPPPKAT : :.:.::.::. :.::.::: : :.:.::.::::: .. ..::: .. .:.: XP_011 FAPVIVEAFKHVSSETDESCKKHLGRVLSIWEERSVYENDVLEQLKQALYGDKKPR---- 50 60 70 80 90 100 150 160 170 180 190 200 pF1KB6 EEKKSLKRTFQQIQEEEDDDYPGSYSPQDPSAGPLLTEELIKALQDLENAASGDATVRQK :::..::. .:... . ::..: : : .:..:::::::::::::.:.:. XP_011 ------KRTYEQIKVDENENCSSLGSPSEP---PQ-TLDLVRALQDLENAASGDAAVHQR 110 120 130 140 150 210 220 230 240 250 260 pF1KB6 IASLPQEVQDVSLLEKITDKEAAERLSKTVDEACLLLAEYNGRLAAELEDRRQLARMLVE ::::: :::.::::.::::::..::::: :..::.:::.::::::::..::.::.:::.. XP_011 IASLPVEVQEVSLLDKITDKESGERLSKMVEDACMLLADYNGRLAAEIDDRKQLTRMLAD 160 170 180 190 200 210 270 280 290 300 310 320 pF1KB6 YTQNQKDVLSEKEKKLEEYKQKLARVTQVRKELKSHIQSLPDLSLLPNVTGGLAPLPSAG . . ::..:.:::.::::::.:::::. :::::.:.:::::::: ::::::. :: :: XP_011 FLRCQKEALAEKEHKLEEYKRKLARVSLVRKELRSRIQSLPDLSRLPNVTGSHMHLPFAG 220 230 240 250 260 270 pF1KB6 DLFSTD :..: : XP_011 DIYSED >>XP_011524352 (OMIM: 610347) PREDICTED: regulation of n (276 aa) initn: 1078 init1: 657 opt: 729 Z-score: 596.9 bits: 118.5 E(85289): 1.7e-26 Smith-Waterman score: 1053; 61.2% identity (84.1% similar) in 276 aa overlap (51-326:15-276) 30 40 50 60 70 80 pF1KB6 QSVQTLSLWLIHHRKHAGPIVSVWHRELRKAKSNRKLTFLYLANDVIQNSKRKGPEFTRE .: :::::::::::::::::::::::::.. XP_011 MRNSNWRFCQTGIYSKPNRKLTFLYLANDVIQNSKRKGPEFTKD 10 20 30 40 90 100 110 120 130 140 pF1KB6 FESVLVDAFSHVAREADEGCKKPLERLLNIWQERSVYGGEFIQQLKLSMEDSKSPPPKAT : :.:.::.::. :.::.::: : :.:.::.::::: .. ..::: .. .:.: XP_011 FAPVIVEAFKHVSSETDESCKKHLGRVLSIWEERSVYENDVLEQLKQALYGDKKPR---- 50 60 70 80 90 100 150 160 170 180 190 200 pF1KB6 EEKKSLKRTFQQIQEEEDDDYPGSYSPQDPSAGPLLTEELIKALQDLENAASGDATVRQK :::..::. .:... . ::..: : : .:..:::::::::::::.:.:. XP_011 ------KRTYEQIKVDENENCSSLGSPSEP---PQ-TLDLVRALQDLENAASGDAAVHQR 110 120 130 140 150 210 220 230 240 250 260 pF1KB6 IASLPQEVQDVSLLEKITDKEAAERLSKTVDEACLLLAEYNGRLAAELEDRRQLARMLVE ::::: :::.::::.::::::..::::: :..::.:::.::::::::..::.::.:::.. XP_011 IASLPVEVQEVSLLDKITDKESGERLSKMVEDACMLLADYNGRLAAEIDDRKQLTRMLAD 160 170 180 190 200 210 270 280 290 300 310 320 pF1KB6 YTQNQKDVLSEKEKKLEEYKQKLARVTQVRKELKSHIQSLPDLSLLPNVTGGLAPLPSAG . . ::..:.:::.::::::.:::::. :::::.:.:::::::: ::::::. :: :: XP_011 FLRCQKEALAEKEHKLEEYKRKLARVSLVRKELRSRIQSLPDLSRLPNVTGSHMHLPFAG 220 230 240 250 260 270 pF1KB6 DLFSTD :..: : XP_011 DIYSED >>NP_001290340 (OMIM: 610347) regulation of nuclear pre- (276 aa) initn: 1078 init1: 657 opt: 729 Z-score: 596.9 bits: 118.5 E(85289): 1.7e-26 Smith-Waterman score: 1053; 61.2% identity (84.1% similar) in 276 aa overlap (51-326:15-276) 30 40 50 60 70 80 pF1KB6 QSVQTLSLWLIHHRKHAGPIVSVWHRELRKAKSNRKLTFLYLANDVIQNSKRKGPEFTRE .: :::::::::::::::::::::::::.. NP_001 MRNSNWRFCQTGIYSKPNRKLTFLYLANDVIQNSKRKGPEFTKD 10 20 30 40 90 100 110 120 130 140 pF1KB6 FESVLVDAFSHVAREADEGCKKPLERLLNIWQERSVYGGEFIQQLKLSMEDSKSPPPKAT : :.:.::.::. :.::.::: : :.:.::.::::: .. ..::: .. .:.: NP_001 FAPVIVEAFKHVSSETDESCKKHLGRVLSIWEERSVYENDVLEQLKQALYGDKKPR---- 50 60 70 80 90 100 150 160 170 180 190 200 pF1KB6 EEKKSLKRTFQQIQEEEDDDYPGSYSPQDPSAGPLLTEELIKALQDLENAASGDATVRQK :::..::. .:... . ::..: : : .:..:::::::::::::.:.:. NP_001 ------KRTYEQIKVDENENCSSLGSPSEP---PQ-TLDLVRALQDLENAASGDAAVHQR 110 120 130 140 150 210 220 230 240 250 260 pF1KB6 IASLPQEVQDVSLLEKITDKEAAERLSKTVDEACLLLAEYNGRLAAELEDRRQLARMLVE ::::: :::.::::.::::::..::::: :..::.:::.::::::::..::.::.:::.. NP_001 IASLPVEVQEVSLLDKITDKESGERLSKMVEDACMLLADYNGRLAAEIDDRKQLTRMLAD 160 170 180 190 200 210 270 280 290 300 310 320 pF1KB6 YTQNQKDVLSEKEKKLEEYKQKLARVTQVRKELKSHIQSLPDLSLLPNVTGGLAPLPSAG . . ::..:.:::.::::::.:::::. :::::.:.:::::::: ::::::. :: :: NP_001 FLRCQKEALAEKEHKLEEYKRKLARVSLVRKELRSRIQSLPDLSRLPNVTGSHMHLPFAG 220 230 240 250 260 270 pF1KB6 DLFSTD :..: : NP_001 DIYSED >>NP_001290341 (OMIM: 610347) regulation of nuclear pre- (276 aa) initn: 1078 init1: 657 opt: 729 Z-score: 596.9 bits: 118.5 E(85289): 1.7e-26 Smith-Waterman score: 1053; 61.2% identity (84.1% similar) in 276 aa overlap (51-326:15-276) 30 40 50 60 70 80 pF1KB6 QSVQTLSLWLIHHRKHAGPIVSVWHRELRKAKSNRKLTFLYLANDVIQNSKRKGPEFTRE .: :::::::::::::::::::::::::.. NP_001 MRNSNWRFCQTGIYSKPNRKLTFLYLANDVIQNSKRKGPEFTKD 10 20 30 40 90 100 110 120 130 140 pF1KB6 FESVLVDAFSHVAREADEGCKKPLERLLNIWQERSVYGGEFIQQLKLSMEDSKSPPPKAT : :.:.::.::. :.::.::: : :.:.::.::::: .. ..::: .. .:.: NP_001 FAPVIVEAFKHVSSETDESCKKHLGRVLSIWEERSVYENDVLEQLKQALYGDKKPR---- 50 60 70 80 90 100 150 160 170 180 190 200 pF1KB6 EEKKSLKRTFQQIQEEEDDDYPGSYSPQDPSAGPLLTEELIKALQDLENAASGDATVRQK :::..::. .:... . ::..: : : .:..:::::::::::::.:.:. NP_001 ------KRTYEQIKVDENENCSSLGSPSEP---PQ-TLDLVRALQDLENAASGDAAVHQR 110 120 130 140 150 210 220 230 240 250 260 pF1KB6 IASLPQEVQDVSLLEKITDKEAAERLSKTVDEACLLLAEYNGRLAAELEDRRQLARMLVE ::::: :::.::::.::::::..::::: :..::.:::.::::::::..::.::.:::.. NP_001 IASLPVEVQEVSLLDKITDKESGERLSKMVEDACMLLADYNGRLAAEIDDRKQLTRMLAD 160 170 180 190 200 210 270 280 290 300 310 320 pF1KB6 YTQNQKDVLSEKEKKLEEYKQKLARVTQVRKELKSHIQSLPDLSLLPNVTGGLAPLPSAG . . ::..:.:::.::::::.:::::. :::::.:.:::::::: ::::::. :: :: NP_001 FLRCQKEALAEKEHKLEEYKRKLARVSLVRKELRSRIQSLPDLSRLPNVTGSHMHLPFAG 220 230 240 250 260 270 pF1KB6 DLFSTD :..: : NP_001 DIYSED 326 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 20:59:15 2016 done: Fri Nov 4 20:59:16 2016 Total Scan time: 7.730 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]