Result of FASTA (ccds) for
pF1KB6478
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6478, 355 aa
1>>>pF1KB6478 355 - 355 aa - 355 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.6475+/-0.000875; mu= 3.1196+/- 0.053
mean_var=207.8910+/-41.162, 0's: 0 Z-trim(113.8): 13 B-trim: 0 in 0/52
Lambda= 0.088952
statistics sampled from 14419 (14431) to 14419 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.769), E-opt: 0.2 (0.443), width: 16
Scan time: 3.130
The best scores are: opt bits E(32554)
CCDS12122.1 SIRT6 gene_id:51548|Hs108|chr19 ( 355) 2423 323.0 2.4e-88
CCDS54199.1 SIRT6 gene_id:51548|Hs108|chr19 ( 328) 1235 170.5 1.8e-42
CCDS82275.1 SIRT6 gene_id:51548|Hs108|chr19 ( 176) 885 125.4 3.7e-29
CCDS11792.1 SIRT7 gene_id:51547|Hs108|chr17 ( 400) 610 90.4 2.9e-18
CCDS82276.1 SIRT6 gene_id:51548|Hs108|chr19 ( 187) 554 82.9 2.4e-16
>>CCDS12122.1 SIRT6 gene_id:51548|Hs108|chr19 (355 aa)
initn: 2423 init1: 2423 opt: 2423 Z-score: 1699.4 bits: 323.0 E(32554): 2.4e-88
Smith-Waterman score: 2423; 99.7% identity (100.0% similar) in 355 aa overlap (1-355:1-355)
10 20 30 40 50 60
pF1KB6 MSVNYAAGLSPYADKGKCGLPEIFDPPEELERKVWELARLVWQSSNVVFHTGAGISTASG
:::::::::::::::::::::::::::::::::::::::::::::.::::::::::::::
CCDS12 MSVNYAAGLSPYADKGKCGLPEIFDPPEELERKVWELARLVWQSSSVVFHTGAGISTASG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 IPDFRGPHGVWTMEERGLAPKFDTTFESARPTQTHMALVQLERVGLLRFLVSQNVDGLHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 IPDFRGPHGVWTMEERGLAPKFDTTFESARPTQTHMALVQLERVGLLRFLVSQNVDGLHV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 RSGFPRDKLAELHGNMFVEECAKCKTQYVRDTVVGTMGLKATGRLCTVAKARGLRACRGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 RSGFPRDKLAELHGNMFVEECAKCKTQYVRDTVVGTMGLKATGRLCTVAKARGLRACRGE
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 LRDTILDWEDSLPDRDLALADEASRNADLSITLGTSLQIRPSGNLPLATKRRGGRLVIVN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 LRDTILDWEDSLPDRDLALADEASRNADLSITLGTSLQIRPSGNLPLATKRRGGRLVIVN
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 LQPTKHDRHADLRIHGYVDEVMTRLMKHLGLEIPAWDGPRVLERALPPLPRPPTPKLEPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 LQPTKHDRHADLRIHGYVDEVMTRLMKHLGLEIPAWDGPRVLERALPPLPRPPTPKLEPK
250 260 270 280 290 300
310 320 330 340 350
pF1KB6 EESPTRINGSIPAGPKQEPCAQHNGSEPASPKRERPTSPAPHRPPKRVKAKAVPS
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 EESPTRINGSIPAGPKQEPCAQHNGSEPASPKRERPTSPAPHRPPKRVKAKAVPS
310 320 330 340 350
>>CCDS54199.1 SIRT6 gene_id:51548|Hs108|chr19 (328 aa)
initn: 1285 init1: 1206 opt: 1235 Z-score: 876.0 bits: 170.5 E(32554): 1.8e-42
Smith-Waterman score: 2179; 92.1% identity (92.4% similar) in 355 aa overlap (1-355:1-328)
10 20 30 40 50 60
pF1KB6 MSVNYAAGLSPYADKGKCGLPEIFDPPEELERKVWELARLVWQSSNVVFHTGAGISTASG
:::::::::::::::::::::::::::::::::::::::::::::.::::::::::::::
CCDS54 MSVNYAAGLSPYADKGKCGLPEIFDPPEELERKVWELARLVWQSSSVVFHTGAGISTASG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 IPDFRGPHGVWTMEERGLAPKFDTTFESARPTQTHMALVQLERVGLLRFLVSQNVDGLHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 IPDFRGPHGVWTMEERGLAPKFDTTFESARPTQTHMALVQLERVGLLRFLVSQNVDGLHV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 RSGFPRDKLAELHGNMFVEECAKCKTQYVRDTVVGTMGLKATGRLCTVAKARGLRACRGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 RSGFPRDKLAELHGNMFVEECAKCKTQYVRDTVVGTMGLKATGRLCTVAKARGLRACR--
130 140 150 160 170
190 200 210 220 230 240
pF1KB6 LRDTILDWEDSLPDRDLALADEASRNADLSITLGTSLQIRPSGNLPLATKRRGGRLVIVN
:::::::::::::::::::::::::::::::::::
CCDS54 -------------------------NADLSITLGTSLQIRPSGNLPLATKRRGGRLVIVN
180 190 200 210
250 260 270 280 290 300
pF1KB6 LQPTKHDRHADLRIHGYVDEVMTRLMKHLGLEIPAWDGPRVLERALPPLPRPPTPKLEPK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 LQPTKHDRHADLRIHGYVDEVMTRLMKHLGLEIPAWDGPRVLERALPPLPRPPTPKLEPK
220 230 240 250 260 270
310 320 330 340 350
pF1KB6 EESPTRINGSIPAGPKQEPCAQHNGSEPASPKRERPTSPAPHRPPKRVKAKAVPS
:::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS54 EESPTRINGSIPAGPKQEPCAQHNGSEPASPKRERPTSPAPHRPPKRVKAKAVPS
280 290 300 310 320
>>CCDS82275.1 SIRT6 gene_id:51548|Hs108|chr19 (176 aa)
initn: 885 init1: 885 opt: 885 Z-score: 637.0 bits: 125.4 E(32554): 3.7e-29
Smith-Waterman score: 885; 99.3% identity (100.0% similar) in 134 aa overlap (73-206:1-134)
50 60 70 80 90 100
pF1KB6 QSSNVVFHTGAGISTASGIPDFRGPHGVWTMEERGLAPKFDTTFESARPTQTHMALVQLE
::::::::::::::::::::::::::::::
CCDS82 MEERGLAPKFDTTFESARPTQTHMALVQLE
10 20 30
110 120 130 140 150 160
pF1KB6 RVGLLRFLVSQNVDGLHVRSGFPRDKLAELHGNMFVEECAKCKTQYVRDTVVGTMGLKAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 RVGLLRFLVSQNVDGLHVRSGFPRDKLAELHGNMFVEECAKCKTQYVRDTVVGTMGLKAT
40 50 60 70 80 90
170 180 190 200 210 220
pF1KB6 GRLCTVAKARGLRACRGELRDTILDWEDSLPDRDLALADEASRNADLSITLGTSLQIRPS
:::::::::::::::::::::::::::::::::::::::::::.
CCDS82 GRLCTVAKARGLRACRGELRDTILDWEDSLPDRDLALADEASRSGPAGTCRWLPSAGEAA
100 110 120 130 140 150
230 240 250 260 270 280
pF1KB6 GNLPLATKRRGGRLVIVNLQPTKHDRHADLRIHGYVDEVMTRLMKHLGLEIPAWDGPRVL
CCDS82 WSSSTCSPPSTTAMLTSASMATLTRS
160 170
>>CCDS11792.1 SIRT7 gene_id:51547|Hs108|chr17 (400 aa)
initn: 546 init1: 225 opt: 610 Z-score: 441.3 bits: 90.4 E(32554): 2.9e-18
Smith-Waterman score: 610; 43.2% identity (65.0% similar) in 280 aa overlap (22-287:77-346)
10 20 30 40 50
pF1KB6 MSVNYAAGLSPYADKGKCGLPEIFDPPEELERKVWELARLVWQSSNVVFHT
:. : ::::. :: ::: : ... .: .:
CCDS11 EGRLLAESADLVTELQGRSRRREGLKRRQEEVCDDPEELRGKVRELASAVRNAKYLVVYT
50 60 70 80 90 100
60 70 80 90 100 110
pF1KB6 GAGISTASGIPDFRGPHGVWTMEERGLAPKFDTTFESARPTQTHMALVQLERVGLLRFLV
:::::::..:::.:::.::::. ..: . . : :.:: :::....:.. :.. .:
CCDS11 GAGISTAASIPDYRGPNGVWTLLQKGRSVSAADLSE-AEPTLTHMSITRLHEQKLVQHVV
110 120 130 140 150 160
120 130 140 150 160
pF1KB6 SQNVDGLHVRSGFPRDKLAELHGNMFVEECAKC--KTQYVR--DTVVGT-MGLKATGRLC
::: ::::.:::.:: ..::::::..: :..: . .::: :.. : . . ::: :
CCDS11 SQNCDGLHLRSGLPRTAISELHGNMYIEVCTSCVPNREYVRVFDVTERTALHRHQTGRTC
170 180 190 200 210 220
170 180 190 200 210 220
pF1KB6 TVAKARGLRACRGELRDTILDW-EDSLPDRDLAL--ADEASRNADLSITLGTSLQI-RPS
. : .:::::. . : . . : : ::. :: . ::.::.. .
CCDS11 --------HKCGTQLRDTIVHFGERGTLGQPLNWEAATEAASRADTILCLGSSLKVLKKY
230 240 250 260 270
230 240 250 260 270
pF1KB6 GNLPLATK--RRGGRLVIVNLQPTKHDRHADLRIHGYVDEVMTRLMKHLGLEIPA---WD
: :: : .: ::::: : .: : :..:: :.:: :: .::::::: :.
CCDS11 PRLWCMTKPPSRRPKLYIVNLQWTPKDDWAALKLHGKCDDVMRLLMAELGLEIPAYSRWQ
280 290 300 310 320 330
280 290 300 310 320 330
pF1KB6 GPRVLERALPPLPRPPTPKLEPKEESPTRINGSIPAGPKQEPCAQHNGSEPASPKRERPT
: .. : :
CCDS11 DP-IFSLATPLRAGEEGSHSRKSLCRSREEAPPGDRGAPLSSAPILGGWFGRGCTKRTKR
340 350 360 370 380 390
>>CCDS82276.1 SIRT6 gene_id:51548|Hs108|chr19 (187 aa)
initn: 965 init1: 538 opt: 554 Z-score: 407.0 bits: 82.9 E(32554): 2.4e-16
Smith-Waterman score: 840; 69.4% identity (70.4% similar) in 206 aa overlap (1-206:1-145)
10 20 30 40 50 60
pF1KB6 MSVNYAAGLSPYADKGKCGLPEIFDPPEELERKVWELARLVWQSSNVVFHTGAGISTASG
:::::::::::::::::::::::::::::::::::::::::::::.::::::::::::::
CCDS82 MSVNYAAGLSPYADKGKCGLPEIFDPPEELERKVWELARLVWQSSSVVFHTGAGISTASG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 IPDFRGPHGVWTMEERGLAPKFDTTFESARPTQTHMALVQLERVGLLRFLVSQNVDGLHV
:::::
CCDS82 IPDFR-------------------------------------------------------
130 140 150 160 170 180
pF1KB6 RSGFPRDKLAELHGNMFVEECAKCKTQYVRDTVVGTMGLKATGRLCTVAKARGLRACRGE
::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS82 ------DKLAELHGNMFVEECAKCKTQYVRDTVVGTMGLKATGRLCTVAKARGLRACRGE
70 80 90 100 110
190 200 210 220 230 240
pF1KB6 LRDTILDWEDSLPDRDLALADEASRNADLSITLGTSLQIRPSGNLPLATKRRGGRLVIVN
:::::::::::::::::::::::::.
CCDS82 LRDTILDWEDSLPDRDLALADEASRSGPAGTCRWLPSAGEAAWSSSTCSPPSTTAMLTSA
120 130 140 150 160 170
355 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 17:18:21 2016 done: Fri Nov 4 17:18:21 2016
Total Scan time: 3.130 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]