FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6482, 356 aa 1>>>pF1KB6482 356 - 356 aa - 356 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.6168+/-0.000317; mu= 6.7420+/- 0.020 mean_var=200.5092+/-40.258, 0's: 0 Z-trim(123.0): 82 B-trim: 574 in 1/53 Lambda= 0.090575 statistics sampled from 41832 (42051) to 41832 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.804), E-opt: 0.2 (0.493), width: 16 Scan time: 8.620 The best scores are: opt bits E(85289) NP_002494 (OMIM: 604495) NF-kappa-B inhibitor beta ( 356) 2436 330.4 3.8e-90 XP_006723290 (OMIM: 604495) PREDICTED: NF-kappa-B ( 351) 1889 258.9 1.2e-68 XP_006723289 (OMIM: 604495) PREDICTED: NF-kappa-B ( 324) 1876 257.2 3.8e-68 NP_001230045 (OMIM: 604495) NF-kappa-B inhibitor b ( 270) 1831 251.2 2e-66 NP_004547 (OMIM: 604548) NF-kappa-B inhibitor epsi ( 500) 372 60.8 7.4e-09 XP_011538132 (OMIM: 164012,615577) PREDICTED: nucl ( 755) 280 49.0 4.1e-05 XP_011538133 (OMIM: 164012,615577) PREDICTED: nucl ( 755) 280 49.0 4.1e-05 NP_001309864 (OMIM: 164012,615577) nuclear factor ( 858) 280 49.1 4.4e-05 NP_001248332 (OMIM: 164012,615577) nuclear factor ( 899) 280 49.1 4.6e-05 NP_002493 (OMIM: 164012,615577) nuclear factor NF- ( 899) 280 49.1 4.6e-05 NP_001275653 (OMIM: 164012,615577) nuclear factor ( 899) 280 49.1 4.6e-05 NP_001309863 (OMIM: 164012,615577) nuclear factor ( 900) 280 49.1 4.6e-05 NP_001070962 (OMIM: 164012,615577) nuclear factor ( 900) 280 49.1 4.6e-05 XP_016871767 (OMIM: 164012,615577) PREDICTED: nucl (1081) 280 49.2 5.2e-05 NP_065390 (OMIM: 164008,612132) NF-kappa-B inhibit ( 317) 263 46.4 0.0001 XP_016882599 (OMIM: 109560) PREDICTED: B-cell lymp ( 356) 237 43.0 0.0012 XP_011525502 (OMIM: 109560) PREDICTED: B-cell lymp ( 378) 237 43.1 0.0012 XP_016882598 (OMIM: 109560) PREDICTED: B-cell lymp ( 434) 237 43.1 0.0014 NP_005169 (OMIM: 109560) B-cell lymphoma 3 protein ( 454) 237 43.2 0.0014 XP_011525499 (OMIM: 109560) PREDICTED: B-cell lymp ( 539) 237 43.2 0.0016 XP_011525500 (OMIM: 109560) PREDICTED: B-cell lymp ( 696) 237 43.3 0.0019 NP_065815 (OMIM: 612184) caskin-1 [Homo sapiens] (1431) 231 42.9 0.0054 XP_011530310 (OMIM: 164011,616576) PREDICTED: nucl ( 916) 221 41.4 0.0097 >>NP_002494 (OMIM: 604495) NF-kappa-B inhibitor beta iso (356 aa) initn: 2436 init1: 2436 opt: 2436 Z-score: 1739.5 bits: 330.4 E(85289): 3.8e-90 Smith-Waterman score: 2436; 100.0% identity (100.0% similar) in 356 aa overlap (1-356:1-356) 10 20 30 40 50 60 pF1KB6 MAGVACLGKAADADEWCDSGLGSLGPDAAAPGGPGLGAELGPGLSWAPLVFGYVTEDGDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MAGVACLGKAADADEWCDSGLGSLGPDAAAPGGPGLGAELGPGLSWAPLVFGYVTEDGDT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 ALHLAVIHQHEPFLDFLLGFSAGTEYMDLQNDLGQTALHLAAILGETSTVEKLYAAGAGL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 ALHLAVIHQHEPFLDFLLGFSAGTEYMDLQNDLGQTALHLAAILGETSTVEKLYAAGAGL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 CVAERRGHTALHLACRVGAHACARALLQPRPRRPREAPDTYLAQGPDRTPDTNHTPVALY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 CVAERRGHTALHLACRVGAHACARALLQPRPRRPREAPDTYLAQGPDRTPDTNHTPVALY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 PDSDLEKEEEESEEDWKLQLEAENYEGHTPLHVAVIHKDVEMVRLLRDAGADLDKPEPTC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 PDSDLEKEEEESEEDWKLQLEAENYEGHTPLHVAVIHKDVEMVRLLRDAGADLDKPEPTC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 GRSPLHLAVEAQAADVLELLLRAGANPAARMYGGRTPLGSAMLRPNPILARLLRAHGAPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 GRSPLHLAVEAQAADVLELLLRAGANPAARMYGGRTPLGSAMLRPNPILARLLRAHGAPE 250 260 270 280 290 300 310 320 330 340 350 pF1KB6 PEGEDEKSGPCSSSSDSDSGDEGDEYDDIVVHSSRSQTRLPPTPASKPLPDDPRPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 PEGEDEKSGPCSSSSDSDSGDEGDEYDDIVVHSSRSQTRLPPTPASKPLPDDPRPV 310 320 330 340 350 >>XP_006723290 (OMIM: 604495) PREDICTED: NF-kappa-B inhi (351 aa) initn: 1889 init1: 1889 opt: 1889 Z-score: 1353.3 bits: 258.9 E(85289): 1.2e-68 Smith-Waterman score: 1889; 100.0% identity (100.0% similar) in 279 aa overlap (78-356:73-351) 50 60 70 80 90 100 pF1KB6 PLVFGYVTEDGDTALHLAVIHQHEPFLDFLLGFSAGTEYMDLQNDLGQTALHLAAILGET :::::::::::::::::::::::::::::: XP_006 GSGRDRAQNYNSQQTLRPQTRFRTTPRAPQLGFSAGTEYMDLQNDLGQTALHLAAILGET 50 60 70 80 90 100 110 120 130 140 150 160 pF1KB6 STVEKLYAAGAGLCVAERRGHTALHLACRVGAHACARALLQPRPRRPREAPDTYLAQGPD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 STVEKLYAAGAGLCVAERRGHTALHLACRVGAHACARALLQPRPRRPREAPDTYLAQGPD 110 120 130 140 150 160 170 180 190 200 210 220 pF1KB6 RTPDTNHTPVALYPDSDLEKEEEESEEDWKLQLEAENYEGHTPLHVAVIHKDVEMVRLLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 RTPDTNHTPVALYPDSDLEKEEEESEEDWKLQLEAENYEGHTPLHVAVIHKDVEMVRLLR 170 180 190 200 210 220 230 240 250 260 270 280 pF1KB6 DAGADLDKPEPTCGRSPLHLAVEAQAADVLELLLRAGANPAARMYGGRTPLGSAMLRPNP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DAGADLDKPEPTCGRSPLHLAVEAQAADVLELLLRAGANPAARMYGGRTPLGSAMLRPNP 230 240 250 260 270 280 290 300 310 320 330 340 pF1KB6 ILARLLRAHGAPEPEGEDEKSGPCSSSSDSDSGDEGDEYDDIVVHSSRSQTRLPPTPASK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ILARLLRAHGAPEPEGEDEKSGPCSSSSDSDSGDEGDEYDDIVVHSSRSQTRLPPTPASK 290 300 310 320 330 340 350 pF1KB6 PLPDDPRPV ::::::::: XP_006 PLPDDPRPV 350 >>XP_006723289 (OMIM: 604495) PREDICTED: NF-kappa-B inhi (324 aa) initn: 1876 init1: 1876 opt: 1876 Z-score: 1344.5 bits: 257.2 E(85289): 3.8e-68 Smith-Waterman score: 1876; 100.0% identity (100.0% similar) in 277 aa overlap (80-356:48-324) 50 60 70 80 90 100 pF1KB6 VFGYVTEDGDTALHLAVIHQHEPFLDFLLGFSAGTEYMDLQNDLGQTALHLAAILGETST :::::::::::::::::::::::::::::: XP_006 PEDLGWARSWARGCRGLPSSSATSLRMGTRFSAGTEYMDLQNDLGQTALHLAAILGETST 20 30 40 50 60 70 110 120 130 140 150 160 pF1KB6 VEKLYAAGAGLCVAERRGHTALHLACRVGAHACARALLQPRPRRPREAPDTYLAQGPDRT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VEKLYAAGAGLCVAERRGHTALHLACRVGAHACARALLQPRPRRPREAPDTYLAQGPDRT 80 90 100 110 120 130 170 180 190 200 210 220 pF1KB6 PDTNHTPVALYPDSDLEKEEEESEEDWKLQLEAENYEGHTPLHVAVIHKDVEMVRLLRDA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PDTNHTPVALYPDSDLEKEEEESEEDWKLQLEAENYEGHTPLHVAVIHKDVEMVRLLRDA 140 150 160 170 180 190 230 240 250 260 270 280 pF1KB6 GADLDKPEPTCGRSPLHLAVEAQAADVLELLLRAGANPAARMYGGRTPLGSAMLRPNPIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GADLDKPEPTCGRSPLHLAVEAQAADVLELLLRAGANPAARMYGGRTPLGSAMLRPNPIL 200 210 220 230 240 250 290 300 310 320 330 340 pF1KB6 ARLLRAHGAPEPEGEDEKSGPCSSSSDSDSGDEGDEYDDIVVHSSRSQTRLPPTPASKPL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ARLLRAHGAPEPEGEDEKSGPCSSSSDSDSGDEGDEYDDIVVHSSRSQTRLPPTPASKPL 260 270 280 290 300 310 350 pF1KB6 PDDPRPV ::::::: XP_006 PDDPRPV 320 >>NP_001230045 (OMIM: 604495) NF-kappa-B inhibitor beta (270 aa) initn: 1831 init1: 1831 opt: 1831 Z-score: 1313.7 bits: 251.2 E(85289): 2e-66 Smith-Waterman score: 1831; 100.0% identity (100.0% similar) in 270 aa overlap (87-356:1-270) 60 70 80 90 100 110 pF1KB6 DGDTALHLAVIHQHEPFLDFLLGFSAGTEYMDLQNDLGQTALHLAAILGETSTVEKLYAA :::::::::::::::::::::::::::::: NP_001 MDLQNDLGQTALHLAAILGETSTVEKLYAA 10 20 30 120 130 140 150 160 170 pF1KB6 GAGLCVAERRGHTALHLACRVGAHACARALLQPRPRRPREAPDTYLAQGPDRTPDTNHTP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GAGLCVAERRGHTALHLACRVGAHACARALLQPRPRRPREAPDTYLAQGPDRTPDTNHTP 40 50 60 70 80 90 180 190 200 210 220 230 pF1KB6 VALYPDSDLEKEEEESEEDWKLQLEAENYEGHTPLHVAVIHKDVEMVRLLRDAGADLDKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VALYPDSDLEKEEEESEEDWKLQLEAENYEGHTPLHVAVIHKDVEMVRLLRDAGADLDKP 100 110 120 130 140 150 240 250 260 270 280 290 pF1KB6 EPTCGRSPLHLAVEAQAADVLELLLRAGANPAARMYGGRTPLGSAMLRPNPILARLLRAH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EPTCGRSPLHLAVEAQAADVLELLLRAGANPAARMYGGRTPLGSAMLRPNPILARLLRAH 160 170 180 190 200 210 300 310 320 330 340 350 pF1KB6 GAPEPEGEDEKSGPCSSSSDSDSGDEGDEYDDIVVHSSRSQTRLPPTPASKPLPDDPRPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GAPEPEGEDEKSGPCSSSSDSDSGDEGDEYDDIVVHSSRSQTRLPPTPASKPLPDDPRPV 220 230 240 250 260 270 >>NP_004547 (OMIM: 604548) NF-kappa-B inhibitor epsilon (500 aa) initn: 464 init1: 200 opt: 372 Z-score: 280.0 bits: 60.8 E(85289): 7.4e-09 Smith-Waterman score: 438; 37.2% identity (55.9% similar) in 288 aa overlap (12-284:202-447) 10 20 30 pF1KB6 MAGVACLGKAADAD-EWCDSGLGSL----------GPDAAA ::: : :: :: ::.: NP_004 TSAPASGPSDGSPQPCTHPPGPVKEPQEKEDADGERADSTYGSSSLTYTLSLLGGPEAED 180 190 200 210 220 230 40 50 60 70 80 pF1KB6 PGG----PGLGAELGPGLSWAPLVFGYVTEDGDTALHLAVIHQHEPFLDFLLGFSAGTEY :. : .:: :.: : . :..::::: .::::::. : :.. : NP_004 PAPRLPLPHVGA-LSPQQLEA---LTYISEDGDTLVHLAVIHEAPAVLLCCLAL-LPQEV 240 250 260 270 280 90 100 110 120 130 140 pF1KB6 MDLQNDLGQTALHLAAILGETSTVEKLYAAGAGLCVAERRGHTALHLACRVGAHACARAL .:.::.: :::::::. : . ..:. : ::. . .:.: ::::.::. :::: : NP_004 LDIQNNLYQTALHLAVHLDQPGAVRALVLKGASRALQDRHGDTALHVACQRQHLACARCL 290 300 310 320 330 340 150 160 170 180 190 200 pF1KB6 LQPRPRRPREAPDTYLAQGPDRTPDTNHTPVALYPDSDLEKEEEESEEDWKLQLEAENYE :. ::. : : :.:. :.:. .:.. NP_004 LEGRPE-------------PGR--GTSHS----------------------LDLQLQNWQ 350 360 210 220 230 240 250 260 pF1KB6 GHTPLHVAVIHKDVEMVRLLRDAGADLDKPEPTCGRSPLHLAVEAQAADVLELLLRAGAN : . ::.:...:. ...:: :::.: : : :.. ::::::.: ....::.:::. NP_004 GLACLHIATLQKNQPLMELLLRNGADIDVQEGTSGKTALHLAVETQERGLVQFLLQAGAQ 370 380 390 400 410 420 270 280 290 300 310 320 pF1KB6 PAARMYGGRTPLGSAMLRPNPILARLLRAHGAPEPEGEDEKSGPCSSSSDSDSGDEGDEY ::: .: ::: : : NP_004 VDARMLNGCTPLHLAAGRGLMGISSTLCKAGADSLLRNVEDETPQDLTEESLVLLPFDDL 430 440 450 460 470 480 >>XP_011538132 (OMIM: 164012,615577) PREDICTED: nuclear (755 aa) initn: 394 init1: 151 opt: 280 Z-score: 212.8 bits: 49.0 E(85289): 4.1e-05 Smith-Waterman score: 379; 34.0% identity (51.7% similar) in 300 aa overlap (56-347:341-596) 30 40 50 60 70 80 pF1KB6 PDAAAPGGPGLGAELGPGLSWAPLVFGYVTEDGDTALHLAVIHQHEPFLD---FLLGFSA :.::: ::::.:: . .. ... . XP_011 RSARALLDYGVTADARALLAGQRHLLTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQ 320 330 340 350 360 370 90 100 110 120 130 140 pF1KB6 GTEYMDLQNDLGQTALHLAAILGETSTVEKLYAAGAGLCVAERRGHTALHLACRVGAHA- ..: : : :: ::::.: :.::.: : .:: . .:.: .:.::: :.:: : XP_011 DLGVVNLTNHLHQTPLHLAVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAP 380 390 400 410 420 430 150 160 170 180 190 200 pF1KB6 -CARALLQPRPRRPREAPDTYLAQGPDRTPDTNHTPVALYPDSDLEKEEEESEEDWKLQL ::::: .: .:. : : XP_011 ELLRALLQ---------------SGAPAVPQLLHMP------------------------ 440 450 210 220 230 240 250 pF1KB6 EAENYEGHTPLHVAVIHKDVEMVRLLRDAGADLDKPEPTCGRSPLHLAVEAQAAD-VLEL ..:: :.:.:: .. : . :: :.::... : ::. ::::.: . : .: XP_011 ---DFEGLYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHL 460 470 480 490 500 260 270 280 290 300 310 pF1KB6 LLRAGANPAARMYGGRTPLGSAMLRPNPILARLLRAHGAPEPEGEDEKSGPCSS--SSDS . . :: :: ..: ::: : : :.::: :: ..: : : .::: XP_011 VTKLRANVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPLPSPPTSDS 510 520 530 540 550 560 320 330 340 350 pF1KB6 DSGDEGDEYDDIVVHSSRSQTRLPPTPASKPLPDDPRPV :: .:: : : . : :..: : : ..: XP_011 DSDSEGPEKD--TRSSFRGHTPLDLTCSTKVKTLLLNAAQNTMEPPLTPPSPAGPGLSLG 570 580 590 600 610 620 >>XP_011538133 (OMIM: 164012,615577) PREDICTED: nuclear (755 aa) initn: 394 init1: 151 opt: 280 Z-score: 212.8 bits: 49.0 E(85289): 4.1e-05 Smith-Waterman score: 379; 34.0% identity (51.7% similar) in 300 aa overlap (56-347:341-596) 30 40 50 60 70 80 pF1KB6 PDAAAPGGPGLGAELGPGLSWAPLVFGYVTEDGDTALHLAVIHQHEPFLD---FLLGFSA :.::: ::::.:: . .. ... . XP_011 RSARALLDYGVTADARALLAGQRHLLTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQ 320 330 340 350 360 370 90 100 110 120 130 140 pF1KB6 GTEYMDLQNDLGQTALHLAAILGETSTVEKLYAAGAGLCVAERRGHTALHLACRVGAHA- ..: : : :: ::::.: :.::.: : .:: . .:.: .:.::: :.:: : XP_011 DLGVVNLTNHLHQTPLHLAVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAP 380 390 400 410 420 430 150 160 170 180 190 200 pF1KB6 -CARALLQPRPRRPREAPDTYLAQGPDRTPDTNHTPVALYPDSDLEKEEEESEEDWKLQL ::::: .: .:. : : XP_011 ELLRALLQ---------------SGAPAVPQLLHMP------------------------ 440 450 210 220 230 240 250 pF1KB6 EAENYEGHTPLHVAVIHKDVEMVRLLRDAGADLDKPEPTCGRSPLHLAVEAQAAD-VLEL ..:: :.:.:: .. : . :: :.::... : ::. ::::.: . : .: XP_011 ---DFEGLYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHL 460 470 480 490 500 260 270 280 290 300 310 pF1KB6 LLRAGANPAARMYGGRTPLGSAMLRPNPILARLLRAHGAPEPEGEDEKSGPCSS--SSDS . . :: :: ..: ::: : : :.::: :: ..: : : .::: XP_011 VTKLRANVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPLPSPPTSDS 510 520 530 540 550 560 320 330 340 350 pF1KB6 DSGDEGDEYDDIVVHSSRSQTRLPPTPASKPLPDDPRPV :: .:: : : . : :..: : : ..: XP_011 DSDSEGPEKD--TRSSFRGHTPLDLTCSTKVKTLLLNAAQNTMEPPLTPPSPAGPGLSLG 570 580 590 600 610 620 >>NP_001309864 (OMIM: 164012,615577) nuclear factor NF-k (858 aa) initn: 394 init1: 151 opt: 280 Z-score: 212.2 bits: 49.1 E(85289): 4.4e-05 Smith-Waterman score: 379; 34.0% identity (51.7% similar) in 300 aa overlap (56-347:444-699) 30 40 50 60 70 80 pF1KB6 PDAAAPGGPGLGAELGPGLSWAPLVFGYVTEDGDTALHLAVIHQHEPFLD---FLLGFSA :.::: ::::.:: . .. ... . NP_001 RSARALLDYGVTADARALLAGQRHLLTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQ 420 430 440 450 460 470 90 100 110 120 130 140 pF1KB6 GTEYMDLQNDLGQTALHLAAILGETSTVEKLYAAGAGLCVAERRGHTALHLACRVGAHA- ..: : : :: ::::.: :.::.: : .:: . .:.: .:.::: :.:: : NP_001 DLGVVNLTNHLHQTPLHLAVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAP 480 490 500 510 520 530 150 160 170 180 190 200 pF1KB6 -CARALLQPRPRRPREAPDTYLAQGPDRTPDTNHTPVALYPDSDLEKEEEESEEDWKLQL ::::: .: .:. : : NP_001 ELLRALLQ---------------SGAPAVPQLLHMP------------------------ 540 550 210 220 230 240 250 pF1KB6 EAENYEGHTPLHVAVIHKDVEMVRLLRDAGADLDKPEPTCGRSPLHLAVEAQAAD-VLEL ..:: :.:.:: .. : . :: :.::... : ::. ::::.: . : .: NP_001 ---DFEGLYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHL 560 570 580 590 600 610 260 270 280 290 300 310 pF1KB6 LLRAGANPAARMYGGRTPLGSAMLRPNPILARLLRAHGAPEPEGEDEKSGPCSS--SSDS . . :: :: ..: ::: : : :.::: :: ..: : : .::: NP_001 VTKLRANVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPLPSPPTSDS 620 630 640 650 660 670 320 330 340 350 pF1KB6 DSGDEGDEYDDIVVHSSRSQTRLPPTPASKPLPDDPRPV :: .:: : : . : :..: : : ..: NP_001 DSDSEGPEKD--TRSSFRGHTPLDLTCSTKVKTLLLNAAQNTMEPPLTPPSPAGPGLSLG 680 690 700 710 720 >>NP_001248332 (OMIM: 164012,615577) nuclear factor NF-k (899 aa) initn: 394 init1: 151 opt: 280 Z-score: 211.9 bits: 49.1 E(85289): 4.6e-05 Smith-Waterman score: 379; 34.0% identity (51.7% similar) in 300 aa overlap (56-347:486-741) 30 40 50 60 70 80 pF1KB6 PDAAAPGGPGLGAELGPGLSWAPLVFGYVTEDGDTALHLAVIHQHEPFLD---FLLGFSA :.::: ::::.:: . .. ... . NP_001 RSARALLDYGVTADARALLAGQRHLLTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQ 460 470 480 490 500 510 90 100 110 120 130 140 pF1KB6 GTEYMDLQNDLGQTALHLAAILGETSTVEKLYAAGAGLCVAERRGHTALHLACRVGAHA- ..: : : :: ::::.: :.::.: : .:: . .:.: .:.::: :.:: : NP_001 DLGVVNLTNHLHQTPLHLAVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAP 520 530 540 550 560 570 150 160 170 180 190 200 pF1KB6 -CARALLQPRPRRPREAPDTYLAQGPDRTPDTNHTPVALYPDSDLEKEEEESEEDWKLQL ::::: .: .:. : : NP_001 ELLRALLQ---------------SGAPAVPQLLHMP------------------------ 580 590 210 220 230 240 250 pF1KB6 EAENYEGHTPLHVAVIHKDVEMVRLLRDAGADLDKPEPTCGRSPLHLAVEAQAAD-VLEL ..:: :.:.:: .. : . :: :.::... : ::. ::::.: . : .: NP_001 ---DFEGLYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHL 600 610 620 630 640 650 260 270 280 290 300 310 pF1KB6 LLRAGANPAARMYGGRTPLGSAMLRPNPILARLLRAHGAPEPEGEDEKSGPCSS--SSDS . . :: :: ..: ::: : : :.::: :: ..: : : .::: NP_001 VTKLRANVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPLPSPPTSDS 660 670 680 690 700 710 320 330 340 350 pF1KB6 DSGDEGDEYDDIVVHSSRSQTRLPPTPASKPLPDDPRPV :: .:: : : . : :..: : : ..: NP_001 DSDSEGPEKD--TRSSFRGHTPLDLTCSTKVKTLLLNAAQNTMEPPLTPPSPAGPGLSLG 720 730 740 750 760 770 >>NP_002493 (OMIM: 164012,615577) nuclear factor NF-kapp (899 aa) initn: 394 init1: 151 opt: 280 Z-score: 211.9 bits: 49.1 E(85289): 4.6e-05 Smith-Waterman score: 379; 34.0% identity (51.7% similar) in 300 aa overlap (56-347:486-741) 30 40 50 60 70 80 pF1KB6 PDAAAPGGPGLGAELGPGLSWAPLVFGYVTEDGDTALHLAVIHQHEPFLD---FLLGFSA :.::: ::::.:: . .. ... . NP_002 RSARALLDYGVTADARALLAGQRHLLTAQDENGDTPLHLAIIHGQTSVIEQIVYVIHHAQ 460 470 480 490 500 510 90 100 110 120 130 140 pF1KB6 GTEYMDLQNDLGQTALHLAAILGETSTVEKLYAAGAGLCVAERRGHTALHLACRVGAHA- ..: : : :: ::::.: :.::.: : .:: . .:.: .:.::: :.:: : NP_002 DLGVVNLTNHLHQTPLHLAVITGQTSVVSFLLRVGADPALLDRHGDSAMHLALRAGAGAP 520 530 540 550 560 570 150 160 170 180 190 200 pF1KB6 -CARALLQPRPRRPREAPDTYLAQGPDRTPDTNHTPVALYPDSDLEKEEEESEEDWKLQL ::::: .: .:. : : NP_002 ELLRALLQ---------------SGAPAVPQLLHMP------------------------ 580 590 210 220 230 240 250 pF1KB6 EAENYEGHTPLHVAVIHKDVEMVRLLRDAGADLDKPEPTCGRSPLHLAVEAQAAD-VLEL ..:: :.:.:: .. : . :: :.::... : ::. ::::.: . : .: NP_002 ---DFEGLYPVHLAVRARSPECLDLLVDSGAEVEATERQGGRTALHLATEMEELGLVTHL 600 610 620 630 640 650 260 270 280 290 300 310 pF1KB6 LLRAGANPAARMYGGRTPLGSAMLRPNPILARLLRAHGAPEPEGEDEKSGPCSS--SSDS . . :: :: ..: ::: : : :.::: :: ..: : : .::: NP_002 VTKLRANVNARTFAGNTPLHLAAGLGYPTLTRLLLKAGADIHAENEEPLCPLPSPPTSDS 660 670 680 690 700 710 320 330 340 350 pF1KB6 DSGDEGDEYDDIVVHSSRSQTRLPPTPASKPLPDDPRPV :: .:: : : . : :..: : : ..: NP_002 DSDSEGPEKD--TRSSFRGHTPLDLTCSTKVKTLLLNAAQNTMEPPLTPPSPAGPGLSLG 720 730 740 750 760 770 356 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 20:59:49 2016 done: Fri Nov 4 20:59:51 2016 Total Scan time: 8.620 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]