FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6483, 328 aa 1>>>pF1KB6483 328 - 328 aa - 328 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.9253+/-0.000351; mu= 19.5033+/- 0.022 mean_var=87.8890+/-17.303, 0's: 0 Z-trim(117.2): 57 B-trim: 957 in 2/54 Lambda= 0.136807 statistics sampled from 28980 (29040) to 28980 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.713), E-opt: 0.2 (0.34), width: 16 Scan time: 8.150 The best scores are: opt bits E(85289) NP_002892 (OMIM: 602735) reticulocalbin-1 precurso ( 331) 1217 249.8 5.8e-66 NP_001124146 (OMIM: 603420) calumenin isoform b pr ( 315) 1118 230.3 4.3e-60 NP_001186601 (OMIM: 603420) calumenin isoform d pr ( 323) 1118 230.3 4.3e-60 NP_001210 (OMIM: 603420) calumenin isoform a precu ( 315) 1098 226.3 6.6e-59 NP_001186600 (OMIM: 603420) calumenin isoform c pr ( 323) 1098 226.3 6.7e-59 NP_001186602 (OMIM: 603420) calumenin isoform e pr ( 224) 723 152.1 1e-36 XP_016868148 (OMIM: 603420) PREDICTED: calumenin i ( 164) 684 144.3 1.7e-34 NP_002893 (OMIM: 602584) reticulocalbin-2 isoform ( 317) 605 129.0 1.3e-29 NP_001258766 (OMIM: 602584) reticulocalbin-2 isofo ( 335) 425 93.5 6.6e-19 NP_057260 (OMIM: 614282) 45 kDa calcium-binding pr ( 362) 248 58.6 2.3e-08 NP_057631 (OMIM: 614282) 45 kDa calcium-binding pr ( 348) 185 46.2 0.00012 >>NP_002892 (OMIM: 602735) reticulocalbin-1 precursor [H (331 aa) initn: 1227 init1: 811 opt: 1217 Z-score: 1305.3 bits: 249.8 E(85289): 5.8e-66 Smith-Waterman score: 1217; 55.7% identity (78.6% similar) in 323 aa overlap (7-328:16-331) 10 20 30 40 50 pF1KB6 MMWRPSVLLLLLLLRHGAQGKPSPDAGPHGQGRVHQAAPLSDAPHDDAHGN .:: :.: . ..::. . . :. . :.. : .: . . NP_002 MARGGRGRRLGLALGLLLALVLAPRVLRAKPTV----RKERVVRPDSELGERPPEDNQ-S 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 FQYDHEAFLGREVAKEFDQLTPEESQARLGRIVDRMDRAGDGDGWVSLAELRAWIAHTQQ ::::::::::.: .: ::::::.::. :::.::::.: .::::.:. ::..:: ..:. NP_002 FQYDHEAFLGKEDSKTFDQLTPDESKERLGKIVDRID--NDGDGFVTTEELKTWIKRVQK 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 RHIRDSVSAAWDTYDTDRDGRVGWEELRNATYGHYAPGE-EFHDVEDAETYKKMLARDER :.: :.:. .: :: :.: ...::: ..::::.: . :::: : .:.:::: :::: NP_002 RYIFDNVAKVWKDYDRDKDDKISWEEYKQATYGYYLGNPAEFHDSSDHHTFKKMLPRDER 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB6 RFRVADQDGDSMATREELTAFLHPEEFPHMRDIVIAETLEDLDRNKDGYVQVEEYIADLY ::..:: .:: :::::.::::::::: ::..::. :::::.:.: ::.:. .:::::.. NP_002 RFKAADLNGDLTATREEFTAFLHPEEFEHMKEIVVLETLEDIDKNGDGFVDQDEYIADMF 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB6 SAEPGEEEPAWVQTERQQFRDFRDLNKDGHLDGSEVGHWVLPPAQDQPLVEANHLLHESD : : . :: :: .::.:: .::::::::.:: .:. ::.:: :. .:: ::..::: NP_002 SHEENGPEPDWVLSEREQFNEFRDLNKDGKLDKDEIRHWILPQDYDHAQAEARHLVYESD 240 250 260 270 280 290 300 310 320 pF1KB6 TDKDGRLSKAEILGNWNMFVGSQATNYGEDLTRHHDEL .:: .:.: ::: ::::::::::::::::::..:::: NP_002 KNKDEKLTKEEILENWNMFVGSQATNYGEDLTKNHDEL 300 310 320 330 >>NP_001124146 (OMIM: 603420) calumenin isoform b precur (315 aa) initn: 1024 init1: 698 opt: 1118 Z-score: 1199.9 bits: 230.3 E(85289): 4.3e-60 Smith-Waterman score: 1121; 50.8% identity (76.9% similar) in 321 aa overlap (8-328:7-315) 10 20 30 40 50 60 pF1KB6 MMWRPSVLLLLLLLRHGAQGKPSPDAGPHGQGRVHQAAPLSDAPHDDAHGNFQYDHEAFL :. : : : .::. . :::. ::: :.::. .:.:::.::: NP_001 MDLRQFLMCLSLCTAFALSKPTEK-----KDRVHHEPQLSDKVHNDAQ-SFDYDHDAFL 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 GREVAKEFDQLTPEESQARLGRIVDRMDRAGDGDGWVSLAELRAWIAHTQQRHIRDSVSA : : :: :::::::::. ::: :::..: .: ::.:. .::..:: :.:...: :.: NP_001 GAEEAKTFDQLTPEESKERLGMIVDKID--ADKDGFVTEGELKSWIKHAQKKYIYDNVEN 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 AWDTYDTDRDGRVGWEELRNATYGHYAPGEEFHDVEDAETYKKMLARDERRFRVADQDGD :. .: ..:: ..:.: ::.::: : : .:. .::.:..::::::..::.::: NP_001 QWQEFDMNQDGLISWDEYRNVTYGTYLDDP---DPDDGFNYKQMMVRDERRFKMADKDGD 120 130 140 150 160 190 200 210 220 230 240 pF1KB6 SMATREELTAFLHPEEFPHMRDIVIAETLEDLDRNKDGYVQVEEYIADLYSAEPGEEEPA .::.::.::::::::. .:.:::. ::.::.:.: ::....::::.:.:: . . .:: NP_001 LIATKEEFTAFLHPEEYDYMKDIVVQETMEDIDKNADGFIDLEEYIGDMYSHDGNTDEPE 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB6 WVQTERQQFRDFRDLNKDGHLDGSEVGHWVLPPAQDQPLVEANHLLHESDTDKDGRLSKA ::.:::.:: .::: :.::..: :. :.:: :. .:: ::..::: .:::.:.: NP_001 WVKTEREQFVEFRDKNRDGKMDKEETKDWILPSDYDHAEAEARHLVYESDQNKDGKLTKE 230 240 250 260 270 280 310 320 pF1KB6 EILGNWNMFVGSQATNYGEDLTRHHDEL ::. ....:::::::..:: :.:: ::. NP_001 EIVDKYDLFVGSQATDFGEALVRH-DEF 290 300 310 >>NP_001186601 (OMIM: 603420) calumenin isoform d precur (323 aa) initn: 1024 init1: 698 opt: 1118 Z-score: 1199.8 bits: 230.3 E(85289): 4.3e-60 Smith-Waterman score: 1121; 50.8% identity (76.9% similar) in 321 aa overlap (8-328:15-323) 10 20 30 40 50 pF1KB6 MMWRPSVLLLLLLLRHGAQGKPSPDAGPHGQGRVHQAAPLSDAPHDDAHGNFQ :. : : : .::. . :::. ::: :.::. .:. NP_001 MKETDLIIMDLRQFLMCLSLCTAFALSKPTEK-----KDRVHHEPQLSDKVHNDAQ-SFD 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 YDHEAFLGREVAKEFDQLTPEESQARLGRIVDRMDRAGDGDGWVSLAELRAWIAHTQQRH :::.:::: : :: :::::::::. ::: :::..: .: ::.:. .::..:: :.:... NP_001 YDHDAFLGAEEAKTFDQLTPEESKERLGMIVDKID--ADKDGFVTEGELKSWIKHAQKKY 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 IRDSVSAAWDTYDTDRDGRVGWEELRNATYGHYAPGEEFHDVEDAETYKKMLARDERRFR : :.: :. .: ..:: ..:.: ::.::: : : .:. .::.:..::::::. NP_001 IYDNVENQWQEFDMNQDGLISWDEYRNVTYGTYLDDP---DPDDGFNYKQMMVRDERRFK 120 130 140 150 160 180 190 200 210 220 230 pF1KB6 VADQDGDSMATREELTAFLHPEEFPHMRDIVIAETLEDLDRNKDGYVQVEEYIADLYSAE .::.::: .::.::.::::::::. .:.:::. ::.::.:.: ::....::::.:.:: . NP_001 MADKDGDLIATKEEFTAFLHPEEYDYMKDIVVQETMEDIDKNADGFIDLEEYIGDMYSHD 170 180 190 200 210 220 240 250 260 270 280 290 pF1KB6 PGEEEPAWVQTERQQFRDFRDLNKDGHLDGSEVGHWVLPPAQDQPLVEANHLLHESDTDK . .:: ::.:::.:: .::: :.::..: :. :.:: :. .:: ::..::: .: NP_001 GNTDEPEWVKTEREQFVEFRDKNRDGKMDKEETKDWILPSDYDHAEAEARHLVYESDQNK 230 240 250 260 270 280 300 310 320 pF1KB6 DGRLSKAEILGNWNMFVGSQATNYGEDLTRHHDEL ::.:.: ::. ....:::::::..:: :.:: ::. NP_001 DGKLTKEEIVDKYDLFVGSQATDFGEALVRH-DEF 290 300 310 320 >>NP_001210 (OMIM: 603420) calumenin isoform a precursor (315 aa) initn: 995 init1: 698 opt: 1098 Z-score: 1178.6 bits: 226.3 E(85289): 6.6e-59 Smith-Waterman score: 1101; 50.8% identity (76.0% similar) in 321 aa overlap (8-328:7-315) 10 20 30 40 50 60 pF1KB6 MMWRPSVLLLLLLLRHGAQGKPSPDAGPHGQGRVHQAAPLSDAPHDDAHGNFQYDHEAFL :. : : : .::. . :::. ::: :.::. .:.:::.::: NP_001 MDLRQFLMCLSLCTAFALSKPTEK-----KDRVHHEPQLSDKVHNDAQ-SFDYDHDAFL 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 GREVAKEFDQLTPEESQARLGRIVDRMDRAGDGDGWVSLAELRAWIAHTQQRHIRDSVSA : : :: :::::::::. :::.::...: :: ::.:.. ::. :: .:.: : ..: NP_001 GAEEAKTFDQLTPEESKERLGKIVSKID--GDKDGFVTVDELKDWIKFAQKRWIYEDVER 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 AWDTYDTDRDGRVGWEELRNATYGHYAPGEEFHDVEDAETYKKMLARDERRFRVADQDGD : .: ..:: :.::: .:::::. : .:. .::.:..::::::..::.::: NP_001 QWKGHDLNEDGLVSWEEYKNATYGYVLDDP---DPDDGFNYKQMMVRDERRFKMADKDGD 120 130 140 150 160 190 200 210 220 230 240 pF1KB6 SMATREELTAFLHPEEFPHMRDIVIAETLEDLDRNKDGYVQVEEYIADLYSAEPGEEEPA .::.::.::::::::. .:.:::. ::.::.:.: ::....::::.:.:: . . .:: NP_001 LIATKEEFTAFLHPEEYDYMKDIVVQETMEDIDKNADGFIDLEEYIGDMYSHDGNTDEPE 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB6 WVQTERQQFRDFRDLNKDGHLDGSEVGHWVLPPAQDQPLVEANHLLHESDTDKDGRLSKA ::.:::.:: .::: :.::..: :. :.:: :. .:: ::..::: .:::.:.: NP_001 WVKTEREQFVEFRDKNRDGKMDKEETKDWILPSDYDHAEAEARHLVYESDQNKDGKLTKE 230 240 250 260 270 280 310 320 pF1KB6 EILGNWNMFVGSQATNYGEDLTRHHDEL ::. ....:::::::..:: :.:: ::. NP_001 EIVDKYDLFVGSQATDFGEALVRH-DEF 290 300 310 >>NP_001186600 (OMIM: 603420) calumenin isoform c precur (323 aa) initn: 995 init1: 698 opt: 1098 Z-score: 1178.5 bits: 226.3 E(85289): 6.7e-59 Smith-Waterman score: 1101; 50.8% identity (76.0% similar) in 321 aa overlap (8-328:15-323) 10 20 30 40 50 pF1KB6 MMWRPSVLLLLLLLRHGAQGKPSPDAGPHGQGRVHQAAPLSDAPHDDAHGNFQ :. : : : .::. . :::. ::: :.::. .:. NP_001 MKETDLIIMDLRQFLMCLSLCTAFALSKPTEK-----KDRVHHEPQLSDKVHNDAQ-SFD 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 YDHEAFLGREVAKEFDQLTPEESQARLGRIVDRMDRAGDGDGWVSLAELRAWIAHTQQRH :::.:::: : :: :::::::::. :::.::...: :: ::.:.. ::. :: .:.: NP_001 YDHDAFLGAEEAKTFDQLTPEESKERLGKIVSKID--GDKDGFVTVDELKDWIKFAQKRW 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 IRDSVSAAWDTYDTDRDGRVGWEELRNATYGHYAPGEEFHDVEDAETYKKMLARDERRFR : ..: : .: ..:: :.::: .:::::. : .:. .::.:..::::::. NP_001 IYEDVERQWKGHDLNEDGLVSWEEYKNATYGYVLDDP---DPDDGFNYKQMMVRDERRFK 120 130 140 150 160 180 190 200 210 220 230 pF1KB6 VADQDGDSMATREELTAFLHPEEFPHMRDIVIAETLEDLDRNKDGYVQVEEYIADLYSAE .::.::: .::.::.::::::::. .:.:::. ::.::.:.: ::....::::.:.:: . NP_001 MADKDGDLIATKEEFTAFLHPEEYDYMKDIVVQETMEDIDKNADGFIDLEEYIGDMYSHD 170 180 190 200 210 220 240 250 260 270 280 290 pF1KB6 PGEEEPAWVQTERQQFRDFRDLNKDGHLDGSEVGHWVLPPAQDQPLVEANHLLHESDTDK . .:: ::.:::.:: .::: :.::..: :. :.:: :. .:: ::..::: .: NP_001 GNTDEPEWVKTEREQFVEFRDKNRDGKMDKEETKDWILPSDYDHAEAEARHLVYESDQNK 230 240 250 260 270 280 300 310 320 pF1KB6 DGRLSKAEILGNWNMFVGSQATNYGEDLTRHHDEL ::.:.: ::. ....:::::::..:: :.:: ::. NP_001 DGKLTKEEIVDKYDLFVGSQATDFGEALVRH-DEF 290 300 310 320 >>NP_001186602 (OMIM: 603420) calumenin isoform e precur (224 aa) initn: 737 init1: 337 opt: 723 Z-score: 780.4 bits: 152.1 E(85289): 1e-36 Smith-Waterman score: 726; 50.7% identity (74.4% similar) in 219 aa overlap (8-226:7-214) 10 20 30 40 50 60 pF1KB6 MMWRPSVLLLLLLLRHGAQGKPSPDAGPHGQGRVHQAAPLSDAPHDDAHGNFQYDHEAFL :. : : : .::. . :::. ::: :.::. .:.:::.::: NP_001 MDLRQFLMCLSLCTAFALSKPTEK-----KDRVHHEPQLSDKVHNDAQ-SFDYDHDAFL 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 GREVAKEFDQLTPEESQARLGRIVDRMDRAGDGDGWVSLAELRAWIAHTQQRHIRDSVSA : : :: :::::::::. :::.::...: :: ::.:.. ::. :: .:.: : ..: NP_001 GAEEAKTFDQLTPEESKERLGKIVSKID--GDKDGFVTVDELKDWIKFAQKRWIYEDVER 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 AWDTYDTDRDGRVGWEELRNATYGHYAPGEEFHDVEDAETYKKMLARDERRFRVADQDGD : .: ..:: :.::: .:::::. : .:. .::.:..::::::..::.::: NP_001 QWKGHDLNEDGLVSWEEYKNATYGYVLDDP---DPDDGFNYKQMMVRDERRFKMADKDGD 120 130 140 150 160 190 200 210 220 230 240 pF1KB6 SMATREELTAFLHPEEFPHMRDIVIAETLEDLDRNKDGYVQVEEYIADLYSAEPGEEEPA .::.::.::::::::. .:.:::. ::.::.:.: ::....:::: NP_001 LIATKEEFTAFLHPEEYDYMKDIVVQETMEDIDKNADGFIDLEEYIGWQAYQGGDR 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB6 WVQTERQQFRDFRDLNKDGHLDGSEVGHWVLPPAQDQPLVEANHLLHESDTDKDGRLSKA >>XP_016868148 (OMIM: 603420) PREDICTED: calumenin isofo (164 aa) initn: 795 init1: 672 opt: 684 Z-score: 740.4 bits: 144.3 E(85289): 1.7e-34 Smith-Waterman score: 684; 55.8% identity (84.8% similar) in 165 aa overlap (164-328:1-164) 140 150 160 170 180 190 pF1KB6 GWEELRNATYGHYAPGEEFHDVEDAETYKKMLARDERRFRVADQDGDSMATREELTAFLH :..::::::..::.::: .::.::.::::: XP_016 MMVRDERRFKMADKDGDLIATKEEFTAFLH 10 20 30 200 210 220 230 240 250 pF1KB6 PEEFPHMRDIVIAETLEDLDRNKDGYVQVEEYIADLYSAEPGEEEPAWVQTERQQFRDFR :::. .:.:::. ::.::.:.: ::....::::.:.:: . . .:: ::.:::.:: .:: XP_016 PEEYDYMKDIVVQETMEDIDKNADGFIDLEEYIGDMYSHDGNTDEPEWVKTEREQFVEFR 40 50 60 70 80 90 260 270 280 290 300 310 pF1KB6 DLNKDGHLDGSEVGHWVLPPAQDQPLVEANHLLHESDTDKDGRLSKAEILGNWNMFVGSQ : :.::..: :. :.:: :. .:: ::..::: .:::.:.: ::. ....::::: XP_016 DKNRDGKMDKEETKDWILPSDYDHAEAEARHLVYESDQNKDGKLTKEEIVDKYDLFVGSQ 100 110 120 130 140 150 320 pF1KB6 ATNYGEDLTRHHDEL ::..:: :.:: ::. XP_016 ATDFGEALVRH-DEF 160 >>NP_002893 (OMIM: 602584) reticulocalbin-2 isoform a pr (317 aa) initn: 580 init1: 397 opt: 605 Z-score: 652.7 bits: 129.0 E(85289): 1.3e-29 Smith-Waterman score: 605; 35.4% identity (64.0% similar) in 311 aa overlap (26-328:17-317) 10 20 30 40 50 pF1KB6 MMWRPSVLLLLLLLRHGAQGKPSPDAGPHGQGRVHQAA-PLSDAPHDDAHGNFQYDHEAF :. : :.... ::.. : ::.::. NP_002 MRLGPRTAALGLLLLCAAAAGAGKAEELHYPLGERRSD-------YDREAL 10 20 30 40 60 70 80 90 100 110 pF1KB6 LG-REVAKEFDQLTPEESQARLGRIVDRMDRAGDGDGWVSLAELRAWIAHTQQRHIRDSV :: .: . :. .: ::.: :: :. ..: :.::... .:: .:: . ... . . NP_002 LGVQEDVDEYVKLGHEEQQKRLQAIIKKIDL--DSDGFLTESELSSWIQMSFKHYAMQEA 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB6 SAAWDTYDTDRDGRVGWEELRNATYGHYAPGEEFHDVEDAE--TYKKMLARDERRFRVAD . . :: . : : :.: : . .: ..::: ...:. .:..::. :. NP_002 KQQFVEYDKNSDDTVTWDEYNIQMYDRVIDFDENTALDDAEEESFRKLHLKDKKRFEKAN 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB6 QDGDSMATREELTAFLHPEEFPHMRDIVIAETLEDLDRNKDGYVQVEEYIADLYSAEP-G ::. . ::. :: :::: .: ..:: :.::. :.: ::.:..::...: : .: . NP_002 QDSGPGLSLEEFIAFEHPEEVDYMTEFVIQEALEEHDKNGDGFVSLEEFLGD-YRWDPTA 170 180 190 200 210 220 240 250 260 270 280 290 pF1KB6 EEEPAWVQTERQQFRDFRDLNKDGHLDGSEVGHWVLPPAQDQPLVEANHLLHESDTDKDG .:.: :. .:...: . : ..::.:: .:. ::.: : :: ::. : : . : NP_002 NEDPEWILVEKDRFVNDYDKDNDGRLDPQELLPWVVPNNQGIAQEEALHLIDEMDLNGDK 230 240 250 260 270 280 300 310 320 pF1KB6 RLSKAEILGNWNMFVGSQATNYGEDLTR---HHDEL .::. ::: : ..:. :.::.::..: .:::: NP_002 KLSEEEILENPDLFLTSEATDYGRQLHDDYFYHDEL 290 300 310 >>NP_001258766 (OMIM: 602584) reticulocalbin-2 isoform b (335 aa) initn: 580 init1: 397 opt: 425 Z-score: 460.4 bits: 93.5 E(85289): 6.6e-19 Smith-Waterman score: 565; 33.7% identity (60.8% similar) in 329 aa overlap (26-328:17-335) 10 20 30 40 50 pF1KB6 MMWRPSVLLLLLLLRHGAQGKPSPDAGPHGQGRVHQAA-PLSDAPHDDAHGNFQYDHEAF :. : :.... ::.. : ::.::. NP_001 MRLGPRTAALGLLLLCAAAAGAGKAEELHYPLGERRSD-------YDREAL 10 20 30 40 60 70 80 90 100 110 pF1KB6 LG-REVAKEFDQLTPEESQARLGRIVDRMDRAGDGDGWVSLAELRAWIAHTQQRHIRDSV :: .: . :. .: ::.: :: :. ..: :.::... .:: .:: . ... . . NP_001 LGVQEDVDEYVKLGHEEQQKRLQAIIKKIDL--DSDGFLTESELSSWIQMSFKHYAMQEA 50 60 70 80 90 100 120 130 140 150 160 pF1KB6 SAAWDTYDTDRDGRVGWEELRNATYGHYAPGEEFHDVEDAE--TYKKMLA---------- . . :: . : : :.: : . .: ..::: ...: .: NP_001 KQQFVEYDKNSDDTVTWDEYNIQMYDRVIDFDENTALDDAEEESFRKEFAICKKQSFCFW 110 120 130 140 150 160 170 180 190 200 210 pF1KB6 --------RDERRFRVADQDGDSMATREELTAFLHPEEFPHMRDIVIAETLEDLDRNKDG .:..::. :.::. . ::. :: :::: .: ..:: :.::. :.: :: NP_001 LLRFNLHLKDKKRFEKANQDSGPGLSLEEFIAFEHPEEVDYMTEFVIQEALEEHDKNGDG 170 180 190 200 210 220 220 230 240 250 260 270 pF1KB6 YVQVEEYIADLYSAEP-GEEEPAWVQTERQQFRDFRDLNKDGHLDGSEVGHWVLPPAQDQ .:..::...: : .: ..:.: :. .:...: . : ..::.:: .:. ::.: : NP_001 FVSLEEFLGD-YRWDPTANEDPEWILVEKDRFVNDYDKDNDGRLDPQELLPWVVPNNQGI 230 240 250 260 270 280 280 290 300 310 320 pF1KB6 PLVEANHLLHESDTDKDGRLSKAEILGNWNMFVGSQATNYGEDLTR---HHDEL :: ::. : : . : .::. ::: : ..:. :.::.::..: .:::: NP_001 AQEEALHLIDEMDLNGDKKLSEEEILENPDLFLTSEATDYGRQLHDDYFYHDEL 290 300 310 320 330 >>NP_057260 (OMIM: 614282) 45 kDa calcium-binding protei (362 aa) initn: 136 init1: 122 opt: 248 Z-score: 271.2 bits: 58.6 E(85289): 2.3e-08 Smith-Waterman score: 359; 25.6% identity (59.5% similar) in 301 aa overlap (47-328:70-362) 20 30 40 50 60 70 pF1KB6 GAQGKPSPDAGPHGQGRVHQAAPLSDAPHDDAHGNFQYDHEAFLGREVAKEFDQ-LTPEE :.: : . .:.:::.... ::. :.. NP_057 NHSSTRERVANREENEILPPDHLNGVKLEMDGHLNRGFHQEVFLGKDLGG-FDEDAEPRR 40 50 60 70 80 90 80 90 100 110 120 130 pF1KB6 SQARLGRIVDRMDRAGDGDGWVSLAELRAWIAHTQQRHIRDSVSAAWDTY---DTDRDGR :. .: : ...: . : .: :.. :: . .:..... . . : : ::. NP_057 SRRKLMVIFSKVDV--NTDRKISAKEMQRWIMEKTAEHFQEAMEESKTHFRAVDPDGDGH 100 110 120 130 140 150 140 150 160 170 180 pF1KB6 VGWEELRN---ATYGHYAPGEEFHDV--------EDAETYKKMLARDERRFRVADQDGDS :.:.: . :. :: .: :. : :: . . .: ... . .: NP_057 VSWDEYKVKFLASKGHSE--KEVADAIRLNEELKVDEETQEVLENLKDRWYQADSPPADL 160 170 180 190 200 210 190 200 210 220 230 pF1KB6 MATREELTAFLHPEEFPHMRDIVIAETLEDLDRNKDGYVQVEEYIA---DLYSAEPGEE- . :.::. .:::::. : ... : ..:::.. : ..: :.:. . :.. NP_057 LLTEEEFLSFLHPEHSRGMLRFMVKEIVRDLDQDGDKQLSVPEFISLPVGTVENQQGQDI 220 230 240 250 260 270 240 250 260 270 280 290 pF1KB6 EPAWVQTERQQFRDFRDLNKDGHLDGSEVGHWVLPPAQDQPLVEANHLLHESDTDKDGRL . ::. ....:... : :.:: . . :. .. : . . : ::.... .: ... .: NP_057 DDNWVKDRKKEFEELIDSNHDGIVTAEELESYMDPMNEYNALNEAKQMIAVADENQNHHL 280 290 300 310 320 330 300 310 320 pF1KB6 SKAEILGNWNMFVGSQATNYGEDLTRHHDEL :.: ..:.::. ..:.... :.:. NP_057 EPEEVLKYSEFFTGSKLVDYARSV---HEEF 340 350 360 328 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 17:13:44 2016 done: Fri Nov 4 17:13:45 2016 Total Scan time: 8.150 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]