FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6484, 356 aa 1>>>pF1KB6484 356 - 356 aa - 356 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.8655+/-0.000902; mu= 13.5601+/- 0.054 mean_var=67.7706+/-13.352, 0's: 0 Z-trim(105.3): 29 B-trim: 63 in 1/50 Lambda= 0.155795 statistics sampled from 8316 (8332) to 8316 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.638), E-opt: 0.2 (0.256), width: 16 Scan time: 2.530 The best scores are: opt bits E(32554) CCDS9352.1 RFC3 gene_id:5983|Hs108|chr13 ( 356) 2370 541.6 3.7e-154 CCDS45025.1 RFC3 gene_id:5983|Hs108|chr13 ( 305) 1961 449.7 1.5e-126 CCDS41843.2 RFC5 gene_id:5985|Hs108|chr12 ( 319) 252 65.6 6.7e-11 CCDS9185.1 RFC5 gene_id:5985|Hs108|chr12 ( 340) 252 65.6 7.1e-11 >>CCDS9352.1 RFC3 gene_id:5983|Hs108|chr13 (356 aa) initn: 2370 init1: 2370 opt: 2370 Z-score: 2881.2 bits: 541.6 E(32554): 3.7e-154 Smith-Waterman score: 2370; 100.0% identity (100.0% similar) in 356 aa overlap (1-356:1-356) 10 20 30 40 50 60 pF1KB6 MSLWVDKYRPCSLGRLDYHKEQAAQLRNLVQCGDFPHLLVYGPSGAGKKTRIMCILRELY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS93 MSLWVDKYRPCSLGRLDYHKEQAAQLRNLVQCGDFPHLLVYGPSGAGKKTRIMCILRELY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 GVGVEKLRIEHQTITTPSKKKIEISTIASNYHLEVNPSDAGNSDRVVIQEMLKTVAQSQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS93 GVGVEKLRIEHQTITTPSKKKIEISTIASNYHLEVNPSDAGNSDRVVIQEMLKTVAQSQQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 LETNSQRDFKVVLLTEVDKLTKDAQHALRRTMEKYMSTCRLILCCNSTSKVIPPIRSRCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS93 LETNSQRDFKVVLLTEVDKLTKDAQHALRRTMEKYMSTCRLILCCNSTSKVIPPIRSRCL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 AVRVPAPSIEDICHVLSTVCKKEGLNLPSQLAHRLAEKSCRNLRKALLMCEACRVQQYPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS93 AVRVPAPSIEDICHVLSTVCKKEGLNLPSQLAHRLAEKSCRNLRKALLMCEACRVQQYPF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 TADQEIPETDWEVYLRETANAIVSQQTPQRLLEVRGRLYELLTHCIPPEIIMKGLLSELL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS93 TADQEIPETDWEVYLRETANAIVSQQTPQRLLEVRGRLYELLTHCIPPEIIMKGLLSELL 250 260 270 280 290 300 310 320 330 340 350 pF1KB6 HNCDGQLKGEVAQMAAYYEHRLQLGSKAIYHLEAFVAKFMALYKKFMEDGLEGMMF :::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS93 HNCDGQLKGEVAQMAAYYEHRLQLGSKAIYHLEAFVAKFMALYKKFMEDGLEGMMF 310 320 330 340 350 >>CCDS45025.1 RFC3 gene_id:5983|Hs108|chr13 (305 aa) initn: 1953 init1: 1953 opt: 1961 Z-score: 2385.5 bits: 449.7 E(32554): 1.5e-126 Smith-Waterman score: 1961; 97.4% identity (98.7% similar) in 304 aa overlap (1-304:1-303) 10 20 30 40 50 60 pF1KB6 MSLWVDKYRPCSLGRLDYHKEQAAQLRNLVQCGDFPHLLVYGPSGAGKKTRIMCILRELY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 MSLWVDKYRPCSLGRLDYHKEQAAQLRNLVQCGDFPHLLVYGPSGAGKKTRIMCILRELY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 GVGVEKLRIEHQTITTPSKKKIEISTIASNYHLEVNPSDAGNSDRVVIQEMLKTVAQSQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 GVGVEKLRIEHQTITTPSKKKIEISTIASNYHLEVNPSDAGNSDRVVIQEMLKTVAQSQQ 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 LETNSQRDFKVVLLTEVDKLTKDAQHALRRTMEKYMSTCRLILCCNSTSKVIPPIRSRCL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 LETNSQRDFKVVLLTEVDKLTKDAQHALRRTMEKYMSTCRLILCCNSTSKVIPPIRSRCL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 AVRVPAPSIEDICHVLSTVCKKEGLNLPSQLAHRLAEKSCRNLRKALLMCEACRVQQYPF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS45 AVRVPAPSIEDICHVLSTVCKKEGLNLPSQLAHRLAEKSCRNLRKALLMCEACRVQQYPF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 TADQEIPETDWEVYLRETANAIVSQQTPQRLLEVRGRLYELLTHCIPPEIIMKGLLSELL :::::::::::::::::::::::::::::::::::::::::::::::::::::. .: CCDS45 TADQEIPETDWEVYLRETANAIVSQQTPQRLLEVRGRLYELLTHCIPPEIIMKAC-KEES 250 260 270 280 290 310 320 330 340 350 pF1KB6 HNCDGQLKGEVAQMAAYYEHRLQLGSKAIYHLEAFVAKFMALYKKFMEDGLEGMMF ..:: CCDS45 RSCDIF 300 >>CCDS41843.2 RFC5 gene_id:5985|Hs108|chr12 (319 aa) initn: 359 init1: 223 opt: 252 Z-score: 309.2 bits: 65.6 E(32554): 6.7e-11 Smith-Waterman score: 348; 26.2% identity (54.4% similar) in 340 aa overlap (5-339:2-308) 10 20 30 40 50 60 pF1KB6 MSLWVDKYRPCSLGRLDYHKEQAAQLRNLVQCGDFPHLLVYGPSGAGKKTRIMCILRELY :.:::: .:. : :.. . ...... .::::.::: :.:: . :. ..:: CCDS41 MVEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYGPPGTGKTSTILACAKQLY 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 GVGVEKLRIEHQTITTPSKKKIEISTIASNYHLEVNPSDAGNSDRVVIQEMLKTVAQSQQ : :..... ::.: :: . : .:. . . :... CCDS41 -------------------KDKEFGSMV----LELNASDDRGID--IIRGPILSFASTR- 60 70 80 90 130 140 150 160 170 180 pF1KB6 LETNSQRDFKVVLLTEVDKLTKDAQHALRRTMEKYMSTCRLILCCNSTSKVIPPIRSRCL : .. ::.:.: :.: .:.:::.::::..::. . :. : :: ::.:: ..::: CCDS41 --TIFKKGFKLVILDEADAMTQDAQNALRRVIEKFTENTRFCLICNYLSKIIPALQSRCT 100 110 120 130 140 190 200 210 220 230 240 pF1KB6 AVRVPAPSIEDICHVLSTVCKKEGLNLPSQLAHRLAEKSCRNLRKALLMCEACRVQQYPF : . : . : : ..: ... . . :. : ..:.:: . .. . CCDS41 RFRFGPLTPELMVPRLEHVVEEEKVDISEDGMKALVTLSSGDMRRALNILQSTNMAFGKV 150 160 170 180 190 200 250 260 270 280 290 pF1KB6 TADQEIPETDWEVYLRETANAIVSQQTPQRLLEVRGRLYELLTHCIPPEIIMKGLLSEL- : . : :. :.. . : . . . :: : . .. .:.:. CCDS41 TEETVYTCTGHP--LKSDIANILDWMLNQDFTTAYRNITELKTL---KGLALHDILTEIH 210 220 230 240 250 260 300 310 320 330 340 350 pF1KB6 --LHNCD--GQLKGEVAQMAAYYEHRLQLGSKAIYHLEAFVAKFMALYKKFMEDGLEGMM .: : .... .. : :.::..:.. .: ...: : CCDS41 LFVHRVDFPSSVRIHLLTKMADIEYRLSVGTNEKIQLSSLIAAFQVTRDLIVAEA 270 280 290 300 310 pF1KB6 F >>CCDS9185.1 RFC5 gene_id:5985|Hs108|chr12 (340 aa) initn: 374 init1: 223 opt: 252 Z-score: 308.7 bits: 65.6 E(32554): 7.1e-11 Smith-Waterman score: 363; 26.4% identity (54.5% similar) in 341 aa overlap (4-339:22-329) 10 20 30 40 pF1KB6 MSLWVDKYRPCSLGRLDYHKEQAAQLRNLVQCGDFPHLLVYG ::.:::: .:. : :.. . ...... .::::.:: CCDS91 METSALKQQEQPAATKIRNLPWVEKYRPQTLNDLISHQDILSTIQKFINEDRLPHLLLYG 10 20 30 40 50 60 50 60 70 80 90 100 pF1KB6 PSGAGKKTRIMCILRELYGVGVEKLRIEHQTITTPSKKKIEISTIASNYHLEVNPSDAGN : :.:: . :. ..:: : :..... ::.: :: . CCDS91 PPGTGKTSTILACAKQLY-------------------KDKEFGSMV----LELNASDDRG 70 80 90 110 120 130 140 150 160 pF1KB6 SDRVVIQEMLKTVAQSQQLETNSQRDFKVVLLTEVDKLTKDAQHALRRTMEKYMSTCRLI : .:. . . :... : .. ::.:.: :.: .:.:::.::::..::. . :. CCDS91 ID--IIRGPILSFASTR---TIFKKGFKLVILDEADAMTQDAQNALRRVIEKFTENTRFC 100 110 120 130 140 150 170 180 190 200 210 220 pF1KB6 LCCNSTSKVIPPIRSRCLAVRVPAPSIEDICHVLSTVCKKEGLNLPSQLAHRLAEKSCRN : :: ::.:: ..::: : . : . : : ..: ... . . :. : . CCDS91 LICNYLSKIIPALQSRCTRFRFGPLTPELMVPRLEHVVEEEKVDISEDGMKALVTLSSGD 160 170 180 190 200 210 230 240 250 260 270 280 pF1KB6 LRKALLMCEACRVQQYPFTADQEIPETDWEVYLRETANAIVSQQTPQRLLEVRGRLYELL .:.:: . .. . : . : :. :.. . : . . . :: CCDS91 MRRALNILQSTNMAFGKVTEETVYTCTGHP--LKSDIANILDWMLNQDFTTAYRNITELK 220 230 240 250 260 270 290 300 310 320 330 pF1KB6 THCIPPEIIMKGLLSEL---LHNCD--GQLKGEVAQMAAYYEHRLQLGSKAIYHLEAFVA : . .. .:.:. .: : .... .. : :.::..:.. .: ...: CCDS91 TL---KGLALHDILTEIHLFVHRVDFPSSVRIHLLTKMADIEYRLSVGTNEKIQLSSLIA 280 290 300 310 320 340 350 pF1KB6 KFMALYKKFMEDGLEGMMF : CCDS91 AFQVTRDLIVAEA 330 340 356 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 16:23:33 2016 done: Fri Nov 4 16:23:33 2016 Total Scan time: 2.530 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]