FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6485, 328 aa 1>>>pF1KB6485 328 - 328 aa - 328 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.1927+/-0.00038; mu= 16.7588+/- 0.024 mean_var=72.7537+/-14.658, 0's: 0 Z-trim(112.7): 61 B-trim: 0 in 0/53 Lambda= 0.150365 statistics sampled from 21735 (21796) to 21735 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.632), E-opt: 0.2 (0.256), width: 16 Scan time: 7.890 The best scores are: opt bits E(85289) NP_002869 (OMIM: 602954,614291) DNA repair protein ( 328) 2075 459.5 4.4e-129 NP_001136043 (OMIM: 602954,614291) DNA repair prot ( 348) 1531 341.5 1.5e-93 NP_598332 (OMIM: 602954,614291) DNA repair protein ( 216) 1069 241.1 1.6e-63 NP_001308739 (OMIM: 602948) DNA repair protein RAD ( 347) 311 76.8 7.2e-14 NP_001308738 (OMIM: 602948) DNA repair protein RAD ( 347) 311 76.8 7.2e-14 NP_001308747 (OMIM: 602948) DNA repair protein RAD ( 347) 311 76.8 7.2e-14 NP_001308748 (OMIM: 602948) DNA repair protein RAD ( 348) 311 76.8 7.2e-14 NP_002868 (OMIM: 602948) DNA repair protein RAD51 ( 350) 311 76.8 7.2e-14 NP_598194 (OMIM: 602948) DNA repair protein RAD51 ( 350) 311 76.8 7.2e-14 NP_001308741 (OMIM: 602948) DNA repair protein RAD ( 351) 311 76.8 7.3e-14 NP_001308743 (OMIM: 602948) DNA repair protein RAD ( 351) 311 76.8 7.3e-14 NP_598193 (OMIM: 602948) DNA repair protein RAD51 ( 384) 311 76.9 7.8e-14 NP_001308750 (OMIM: 602948) DNA repair protein RAD ( 425) 311 76.9 8.4e-14 XP_016877034 (OMIM: 602948) PREDICTED: DNA repair ( 500) 297 73.9 7.8e-13 XP_011535352 (OMIM: 602948) PREDICTED: DNA repair ( 274) 281 70.3 5.4e-12 XP_011535353 (OMIM: 602948) PREDICTED: DNA repair ( 258) 279 69.8 7e-12 NP_001308744 (OMIM: 602948) DNA repair protein RAD ( 332) 270 67.9 3.3e-11 XP_011520159 (OMIM: 114480,179617,614508) PREDICTE ( 339) 242 61.9 2.3e-09 XP_011520160 (OMIM: 114480,179617,614508) PREDICTE ( 339) 242 61.9 2.3e-09 XP_006720689 (OMIM: 114480,179617,614508) PREDICTE ( 339) 242 61.9 2.3e-09 NP_002866 (OMIM: 114480,179617,614508) DNA repair ( 339) 242 61.9 2.3e-09 XP_011520162 (OMIM: 114480,179617,614508) PREDICTE ( 339) 242 61.9 2.3e-09 XP_011520161 (OMIM: 114480,179617,614508) PREDICTE ( 339) 242 61.9 2.3e-09 XP_011520163 (OMIM: 114480,179617,614508) PREDICTE ( 280) 196 51.8 2e-06 NP_001157742 (OMIM: 114480,179617,614508) DNA repa ( 280) 196 51.8 2e-06 NP_597994 (OMIM: 114480,179617,614508) DNA repair ( 340) 191 50.8 4.9e-06 NP_001157741 (OMIM: 114480,179617,614508) DNA repa ( 340) 191 50.8 4.9e-06 NP_008999 (OMIM: 602721) meiotic recombination pro ( 340) 184 49.3 1.4e-05 XP_011535440 (OMIM: 114480,600675,613972) PREDICTE ( 346) 182 48.9 1.9e-05 NP_001093589 (OMIM: 114480,600675,613972) DNA repa ( 346) 182 48.9 1.9e-05 XP_005268103 (OMIM: 114480,600675,613972) PREDICTE ( 346) 182 48.9 1.9e-05 NP_001093588 (OMIM: 114480,600675,613972) DNA repa ( 346) 182 48.9 1.9e-05 NP_005423 (OMIM: 114480,600675,613972) DNA repair ( 346) 182 48.9 1.9e-05 XP_011528137 (OMIM: 602721) PREDICTED: meiotic rec ( 362) 182 48.9 2e-05 XP_011528136 (OMIM: 602721) PREDICTED: meiotic rec ( 362) 182 48.9 2e-05 XP_006722065 (OMIM: 189960,602774,613390,613399) P ( 342) 163 44.7 0.00033 NP_478123 (OMIM: 189960,602774,613390,613399) DNA ( 376) 163 44.8 0.00035 XP_006722064 (OMIM: 189960,602774,613390,613399) P ( 377) 163 44.8 0.00035 NP_001308746 (OMIM: 602948) DNA repair protein RAD ( 231) 156 43.1 0.00069 XP_016877036 (OMIM: 602948) PREDICTED: DNA repair ( 306) 156 43.2 0.00086 XP_011520164 (OMIM: 114480,179617,614508) PREDICTE ( 215) 154 42.6 0.00088 >>NP_002869 (OMIM: 602954,614291) DNA repair protein RAD (328 aa) initn: 2075 init1: 2075 opt: 2075 Z-score: 2438.4 bits: 459.5 E(85289): 4.4e-129 Smith-Waterman score: 2075; 100.0% identity (100.0% similar) in 328 aa overlap (1-328:1-328) 10 20 30 40 50 60 pF1KB6 MGVLRVGLCPGLTEEMIQLLRSHRIKTVVDLVSADLEEVAQKCGLSYKALVALRRVLLAQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MGVLRVGLCPGLTEEMIQLLRSHRIKTVVDLVSADLEEVAQKCGLSYKALVALRRVLLAQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 FSAFPVNGADLYEELKTSTAILSTGIGSLDKLLDAGLYTGEVTEIVGGPGSGKTQVCLCM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 FSAFPVNGADLYEELKTSTAILSTGIGSLDKLLDAGLYTGEVTEIVGGPGSGKTQVCLCM 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 AANVAHGLQQNVLYVDSNGGLTASRLLQLLQAKTQDEEEQAEALRRIQVVHAFDIFQMLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 AANVAHGLQQNVLYVDSNGGLTASRLLQLLQAKTQDEEEQAEALRRIQVVHAFDIFQMLD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 VLQELRGTVAQQVTGSSGTVKVVVVDSVTAVVSPLLGGQQREGLALMMQLARELKTLARD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 VLQELRGTVAQQVTGSSGTVKVVVVDSVTAVVSPLLGGQQREGLALMMQLARELKTLARD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 LGMAVVVTNHITRDRDSGRLKPALGRSWSFVPSTRILLDTIEGAGASGGRRMACLAKSSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 LGMAVVVTNHITRDRDSGRLKPALGRSWSFVPSTRILLDTIEGAGASGGRRMACLAKSSR 250 260 270 280 290 300 310 320 pF1KB6 QPTGFQEMVDIGTWGTSEQSATLQGDQT :::::::::::::::::::::::::::: NP_002 QPTGFQEMVDIGTWGTSEQSATLQGDQT 310 320 >>NP_001136043 (OMIM: 602954,614291) DNA repair protein (348 aa) initn: 1824 init1: 1530 opt: 1531 Z-score: 1800.3 bits: 341.5 E(85289): 1.5e-93 Smith-Waterman score: 1783; 85.6% identity (89.4% similar) in 348 aa overlap (1-328:1-348) 10 20 30 40 50 pF1KB6 MGVLRVGLCPGLTEEMIQLLRSHRIKTVVDLVSADLEEVAQKCGLSYKALVALRRVLLA- ::::::::::::::::::::::::::::::::::::::::::::::::. : :. NP_001 MGVLRVGLCPGLTEEMIQLLRSHRIKTVVDLVSADLEEVAQKCGLSYKTWRAHSSGNLGG 10 20 30 40 50 60 60 70 80 90 100 pF1KB6 -QFSAFPV--NGADLYEELKTS------TAILS--------TGIGS--LDKLLDAGLYTG :. :. . . . . :: . : :: :.... :::::::::::: NP_001 LQLPQVPAGRSWSGVRNALKKAGLGHGGTDGLSLNAFDERGTAVSTSRLDKLLDAGLYTG 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB6 EVTEIVGGPGSGKTQVCLCMAANVAHGLQQNVLYVDSNGGLTASRLLQLLQAKTQDEEEQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 EVTEIVGGPGSGKTQVCLCMAANVAHGLQQNVLYVDSNGGLTASRLLQLLQAKTQDEEEQ 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB6 AEALRRIQVVHAFDIFQMLDVLQELRGTVAQQVTGSSGTVKVVVVDSVTAVVSPLLGGQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 AEALRRIQVVHAFDIFQMLDVLQELRGTVAQQVTGSSGTVKVVVVDSVTAVVSPLLGGQQ 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB6 REGLALMMQLARELKTLARDLGMAVVVTNHITRDRDSGRLKPALGRSWSFVPSTRILLDT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 REGLALMMQLARELKTLARDLGMAVVVTNHITRDRDSGRLKPALGRSWSFVPSTRILLDT 250 260 270 280 290 300 290 300 310 320 pF1KB6 IEGAGASGGRRMACLAKSSRQPTGFQEMVDIGTWGTSEQSATLQGDQT :::::::::::::::::::::::::::::::::::::::::::::::: NP_001 IEGAGASGGRRMACLAKSSRQPTGFQEMVDIGTWGTSEQSATLQGDQT 310 320 330 340 >>NP_598332 (OMIM: 602954,614291) DNA repair protein RAD (216 aa) initn: 1069 init1: 1069 opt: 1069 Z-score: 1261.6 bits: 241.1 E(85289): 1.6e-63 Smith-Waterman score: 1141; 65.9% identity (65.9% similar) in 328 aa overlap (1-328:1-216) 10 20 30 40 50 60 pF1KB6 MGVLRVGLCPGLTEEMIQLLRSHRIKTVVDLVSADLEEVAQKCGLSYKALVALRRVLLAQ ::::::::::::::::::::::::::::::::::::::::::::::::: NP_598 MGVLRVGLCPGLTEEMIQLLRSHRIKTVVDLVSADLEEVAQKCGLSYKA----------- 10 20 30 40 70 80 90 100 110 120 pF1KB6 FSAFPVNGADLYEELKTSTAILSTGIGSLDKLLDAGLYTGEVTEIVGGPGSGKTQVCLCM NP_598 ------------------------------------------------------------ 130 140 150 160 170 180 pF1KB6 AANVAHGLQQNVLYVDSNGGLTASRLLQLLQAKTQDEEEQAEALRRIQVVHAFDIFQMLD ::::::::::::::::::: NP_598 -----------------------------------------EALRRIQVVHAFDIFQMLD 50 60 190 200 210 220 230 240 pF1KB6 VLQELRGTVAQQVTGSSGTVKVVVVDSVTAVVSPLLGGQQREGLALMMQLARELKTLARD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_598 VLQELRGTVAQQVTGSSGTVKVVVVDSVTAVVSPLLGGQQREGLALMMQLARELKTLARD 70 80 90 100 110 120 250 260 270 280 290 300 pF1KB6 LGMAVVVTNHITRDRDSGRLKPALGRSWSFVPSTRILLDTIEGAGASGGRRMACLAKSSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_598 LGMAVVVTNHITRDRDSGRLKPALGRSWSFVPSTRILLDTIEGAGASGGRRMACLAKSSR 130 140 150 160 170 180 310 320 pF1KB6 QPTGFQEMVDIGTWGTSEQSATLQGDQT :::::::::::::::::::::::::::: NP_598 QPTGFQEMVDIGTWGTSEQSATLQGDQT 190 200 210 >>NP_001308739 (OMIM: 602948) DNA repair protein RAD51 h (347 aa) initn: 257 init1: 131 opt: 311 Z-score: 370.0 bits: 76.8 E(85289): 7.2e-14 Smith-Waterman score: 324; 28.2% identity (57.1% similar) in 354 aa overlap (11-325:10-346) 10 20 30 40 50 60 pF1KB6 MGVLRVGLCPGLTEEMIQLLRSHRIKTVVDLVSADLEEVAQKCGLSYKALVALRRVLLAQ ::..:. . : :.: : :.. . :. . ::::... : .... NP_001 MGSKKLKRVGLSQELCDRLSRHQILTCQDFLCLSPLELMKVTGLSYRGVHELL-CMVSR 10 20 30 40 50 70 80 90 100 110 pF1KB6 FSAFPVNGADLYEELKT---STAILSTGIGSLDKLLDAGLYTGEVTEIVGGPGSGKTQVC : .. : . .. : :.::: ...::. : .:. : .:::.: :: :::: : NP_001 ACAPKMQTAYGIKAQRSADFSPAFLSTTLSALDEALHGGVACGSLTEITGPPGCGKTQFC 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 LCMA------ANVAHGLQQNVLYVDSNGGLTASRLLQLLQAKTQDEEEQAEALRRIQV-V . :. .:.. ::. :.:.:......: ::... ... . : : . : NP_001 IMMSILATLPTNMG-GLEGAVVYIDTESAFSAERLVEIAESRFPRYFNTEEKLLLTSSKV 120 130 140 150 160 170 180 190 200 210 220 pF1KB6 HAFDIFQMLDVLQELRGTVAQQVTGSSGTVKVVVVDSVTAVV----SPLLGGQQREGLAL : . . .:::... .. ... :.: .:.:..:::..:: . : :. .: . NP_001 HLYRELTCDEVLQRIE-SLEEEII-SKG-IKLVILDSVASVVRKEFDAQLQGNLKERNKF 180 190 200 210 220 230 230 240 250 260 pF1KB6 MMQLARELKTLARDLGMAVVVTNHITRDRDSGRL-------KPA---------------- . . : :: ::..... :..::.:: :: : .:: NP_001 LAREASSLKYLAEEFSIPVILTNQITTHL-SGALASQADLVSPADDLSLSEGTSGSSCVI 240 250 260 270 280 290 270 280 290 300 310 320 pF1KB6 --LGRSWSFVPSTRILLDTIEGAGASGGRRMACLAKSSRQPTGFQEMVDIGTWGTSEQSA :: .:: .::..:. ... ::. .::: : : .: . .:.. NP_001 AALGNTWSHSVNTRLILQYLDSE-----RRQILIAKSPLAP--FTSFV----YTIKEEGL 300 310 320 330 340 pF1KB6 TLQGDQT .::: NP_001 VLQGL >>NP_001308738 (OMIM: 602948) DNA repair protein RAD51 h (347 aa) initn: 257 init1: 131 opt: 311 Z-score: 370.0 bits: 76.8 E(85289): 7.2e-14 Smith-Waterman score: 324; 28.2% identity (57.1% similar) in 354 aa overlap (11-325:10-346) 10 20 30 40 50 60 pF1KB6 MGVLRVGLCPGLTEEMIQLLRSHRIKTVVDLVSADLEEVAQKCGLSYKALVALRRVLLAQ ::..:. . : :.: : :.. . :. . ::::... : .... NP_001 MGSKKLKRVGLSQELCDRLSRHQILTCQDFLCLSPLELMKVTGLSYRGVHELL-CMVSR 10 20 30 40 50 70 80 90 100 110 pF1KB6 FSAFPVNGADLYEELKT---STAILSTGIGSLDKLLDAGLYTGEVTEIVGGPGSGKTQVC : .. : . .. : :.::: ...::. : .:. : .:::.: :: :::: : NP_001 ACAPKMQTAYGIKAQRSADFSPAFLSTTLSALDEALHGGVACGSLTEITGPPGCGKTQFC 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 LCMA------ANVAHGLQQNVLYVDSNGGLTASRLLQLLQAKTQDEEEQAEALRRIQV-V . :. .:.. ::. :.:.:......: ::... ... . : : . : NP_001 IMMSILATLPTNMG-GLEGAVVYIDTESAFSAERLVEIAESRFPRYFNTEEKLLLTSSKV 120 130 140 150 160 170 180 190 200 210 220 pF1KB6 HAFDIFQMLDVLQELRGTVAQQVTGSSGTVKVVVVDSVTAVV----SPLLGGQQREGLAL : . . .:::... .. ... :.: .:.:..:::..:: . : :. .: . NP_001 HLYRELTCDEVLQRIE-SLEEEII-SKG-IKLVILDSVASVVRKEFDAQLQGNLKERNKF 180 190 200 210 220 230 230 240 250 260 pF1KB6 MMQLARELKTLARDLGMAVVVTNHITRDRDSGRL-------KPA---------------- . . : :: ::..... :..::.:: :: : .:: NP_001 LAREASSLKYLAEEFSIPVILTNQITTHL-SGALASQADLVSPADDLSLSEGTSGSSCVI 240 250 260 270 280 290 270 280 290 300 310 320 pF1KB6 --LGRSWSFVPSTRILLDTIEGAGASGGRRMACLAKSSRQPTGFQEMVDIGTWGTSEQSA :: .:: .::..:. ... ::. .::: : : .: . .:.. NP_001 AALGNTWSHSVNTRLILQYLDSE-----RRQILIAKSPLAP--FTSFV----YTIKEEGL 300 310 320 330 340 pF1KB6 TLQGDQT .::: NP_001 VLQGL >>NP_001308747 (OMIM: 602948) DNA repair protein RAD51 h (347 aa) initn: 257 init1: 131 opt: 311 Z-score: 370.0 bits: 76.8 E(85289): 7.2e-14 Smith-Waterman score: 324; 28.2% identity (57.1% similar) in 354 aa overlap (11-325:10-346) 10 20 30 40 50 60 pF1KB6 MGVLRVGLCPGLTEEMIQLLRSHRIKTVVDLVSADLEEVAQKCGLSYKALVALRRVLLAQ ::..:. . : :.: : :.. . :. . ::::... : .... NP_001 MGSKKLKRVGLSQELCDRLSRHQILTCQDFLCLSPLELMKVTGLSYRGVHELL-CMVSR 10 20 30 40 50 70 80 90 100 110 pF1KB6 FSAFPVNGADLYEELKT---STAILSTGIGSLDKLLDAGLYTGEVTEIVGGPGSGKTQVC : .. : . .. : :.::: ...::. : .:. : .:::.: :: :::: : NP_001 ACAPKMQTAYGIKAQRSADFSPAFLSTTLSALDEALHGGVACGSLTEITGPPGCGKTQFC 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 LCMA------ANVAHGLQQNVLYVDSNGGLTASRLLQLLQAKTQDEEEQAEALRRIQV-V . :. .:.. ::. :.:.:......: ::... ... . : : . : NP_001 IMMSILATLPTNMG-GLEGAVVYIDTESAFSAERLVEIAESRFPRYFNTEEKLLLTSSKV 120 130 140 150 160 170 180 190 200 210 220 pF1KB6 HAFDIFQMLDVLQELRGTVAQQVTGSSGTVKVVVVDSVTAVV----SPLLGGQQREGLAL : . . .:::... .. ... :.: .:.:..:::..:: . : :. .: . NP_001 HLYRELTCDEVLQRIE-SLEEEII-SKG-IKLVILDSVASVVRKEFDAQLQGNLKERNKF 180 190 200 210 220 230 230 240 250 260 pF1KB6 MMQLARELKTLARDLGMAVVVTNHITRDRDSGRL-------KPA---------------- . . : :: ::..... :..::.:: :: : .:: NP_001 LAREASSLKYLAEEFSIPVILTNQITTHL-SGALASQADLVSPADDLSLSEGTSGSSCVI 240 250 260 270 280 290 270 280 290 300 310 320 pF1KB6 --LGRSWSFVPSTRILLDTIEGAGASGGRRMACLAKSSRQPTGFQEMVDIGTWGTSEQSA :: .:: .::..:. ... ::. .::: : : .: . .:.. NP_001 AALGNTWSHSVNTRLILQYLDSE-----RRQILIAKSPLAP--FTSFV----YTIKEEGL 300 310 320 330 340 pF1KB6 TLQGDQT .::: NP_001 VLQGQ >>NP_001308748 (OMIM: 602948) DNA repair protein RAD51 h (348 aa) initn: 257 init1: 131 opt: 311 Z-score: 370.0 bits: 76.8 E(85289): 7.2e-14 Smith-Waterman score: 321; 28.6% identity (56.8% similar) in 336 aa overlap (11-305:10-333) 10 20 30 40 50 60 pF1KB6 MGVLRVGLCPGLTEEMIQLLRSHRIKTVVDLVSADLEEVAQKCGLSYKALVALRRVLLAQ ::..:. . : :.: : :.. . :. . ::::... : . ... NP_001 MGSKKLKRVGLSQELCDRLSRHQILTCQDFLCLSPLELMKVTGLSYRGVHEL--LCMVS 10 20 30 40 50 70 80 90 100 110 pF1KB6 FSAFP----VNGADLYEELKTSTAILSTGIGSLDKLLDAGLYTGEVTEIVGGPGSGKTQV . : . : . : :.::: ...::. : .:. : .:::.: :: :::: NP_001 RACAPKMQTAYGIKAQRSADFSPAFLSTTLSALDEALHGGVACGSLTEITGPPGCGKTQF 60 70 80 90 100 110 120 130 140 150 160 pF1KB6 CLCMA------ANVAHGLQQNVLYVDSNGGLTASRLLQLLQAKTQDEEEQAEALRRIQV- :. :. .:.. ::. :.:.:......: ::... ... . : : . NP_001 CIMMSILATLPTNMG-GLEGAVVYIDTESAFSAERLVEIAESRFPRYFNTEEKLLLTSSK 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB6 VHAFDIFQMLDVLQELRGTVAQQVTGSSGTVKVVVVDSVTAVV----SPLLGGQQREGLA :: . . .:::... .. ... :.: .:.:..:::..:: . : :. .: NP_001 VHLYRELTCDEVLQRIE-SLEEEII-SKG-IKLVILDSVASVVRKEFDAQLQGNLKERNK 180 190 200 210 220 230 230 240 250 260 pF1KB6 LMMQLARELKTLARDLGMAVVVTNHITRDRDSGRL-------KPA--------------- .. . : :: ::..... :..::.:: :: : .:: NP_001 FLAREASSLKYLAEEFSIPVILTNQITTHL-SGALASQADLVSPADDLSLSEGTSGSSCV 240 250 260 270 280 290 270 280 290 300 310 pF1KB6 ---LGRSWSFVPSTRILLDTIEGAGASGGRRMACLAKSSRQP-TGFQEMVDIGTWGTSEQ :: .:: .::..:. ... ::. .::: : :.: NP_001 IAALGNTWSHSVNTRLILQYLDSE-----RRQILIAKSPLAPFTSFVYTIKEEGLVLQAG 300 310 320 330 340 320 pF1KB6 SATLQGDQT NP_001 K >>NP_002868 (OMIM: 602948) DNA repair protein RAD51 homo (350 aa) initn: 257 init1: 131 opt: 311 Z-score: 369.9 bits: 76.8 E(85289): 7.2e-14 Smith-Waterman score: 321; 28.6% identity (56.8% similar) in 336 aa overlap (11-305:10-333) 10 20 30 40 50 60 pF1KB6 MGVLRVGLCPGLTEEMIQLLRSHRIKTVVDLVSADLEEVAQKCGLSYKALVALRRVLLAQ ::..:. . : :.: : :.. . :. . ::::... : . ... NP_002 MGSKKLKRVGLSQELCDRLSRHQILTCQDFLCLSPLELMKVTGLSYRGVHEL--LCMVS 10 20 30 40 50 70 80 90 100 110 pF1KB6 FSAFP----VNGADLYEELKTSTAILSTGIGSLDKLLDAGLYTGEVTEIVGGPGSGKTQV . : . : . : :.::: ...::. : .:. : .:::.: :: :::: NP_002 RACAPKMQTAYGIKAQRSADFSPAFLSTTLSALDEALHGGVACGSLTEITGPPGCGKTQF 60 70 80 90 100 110 120 130 140 150 160 pF1KB6 CLCMA------ANVAHGLQQNVLYVDSNGGLTASRLLQLLQAKTQDEEEQAEALRRIQV- :. :. .:.. ::. :.:.:......: ::... ... . : : . NP_002 CIMMSILATLPTNMG-GLEGAVVYIDTESAFSAERLVEIAESRFPRYFNTEEKLLLTSSK 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB6 VHAFDIFQMLDVLQELRGTVAQQVTGSSGTVKVVVVDSVTAVV----SPLLGGQQREGLA :: . . .:::... .. ... :.: .:.:..:::..:: . : :. .: NP_002 VHLYRELTCDEVLQRIE-SLEEEII-SKG-IKLVILDSVASVVRKEFDAQLQGNLKERNK 180 190 200 210 220 230 230 240 250 260 pF1KB6 LMMQLARELKTLARDLGMAVVVTNHITRDRDSGRL-------KPA--------------- .. . : :: ::..... :..::.:: :: : .:: NP_002 FLAREASSLKYLAEEFSIPVILTNQITTHL-SGALASQADLVSPADDLSLSEGTSGSSCV 240 250 260 270 280 290 270 280 290 300 310 pF1KB6 ---LGRSWSFVPSTRILLDTIEGAGASGGRRMACLAKSSRQP-TGFQEMVDIGTWGTSEQ :: .:: .::..:. ... ::. .::: : :.: NP_002 IAALGNTWSHSVNTRLILQYLDSE-----RRQILIAKSPLAPFTSFVYTIKEEGLVLQAY 300 310 320 330 340 320 pF1KB6 SATLQGDQT NP_002 GNS 350 >>NP_598194 (OMIM: 602948) DNA repair protein RAD51 homo (350 aa) initn: 257 init1: 131 opt: 311 Z-score: 369.9 bits: 76.8 E(85289): 7.2e-14 Smith-Waterman score: 326; 28.1% identity (57.6% similar) in 356 aa overlap (11-327:10-348) 10 20 30 40 50 60 pF1KB6 MGVLRVGLCPGLTEEMIQLLRSHRIKTVVDLVSADLEEVAQKCGLSYKALVALRRVLLAQ ::..:. . : :.: : :.. . :. . ::::... : .... NP_598 MGSKKLKRVGLSQELCDRLSRHQILTCQDFLCLSPLELMKVTGLSYRGVHELL-CMVSR 10 20 30 40 50 70 80 90 100 110 pF1KB6 FSAFPVNGADLYEELKT---STAILSTGIGSLDKLLDAGLYTGEVTEIVGGPGSGKTQVC : .. : . .. : :.::: ...::. : .:. : .:::.: :: :::: : NP_598 ACAPKMQTAYGIKAQRSADFSPAFLSTTLSALDEALHGGVACGSLTEITGPPGCGKTQFC 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 LCMA------ANVAHGLQQNVLYVDSNGGLTASRLLQLLQAKTQDEEEQAEALRRIQV-V . :. .:.. ::. :.:.:......: ::... ... . : : . : NP_598 IMMSILATLPTNMG-GLEGAVVYIDTESAFSAERLVEIAESRFPRYFNTEEKLLLTSSKV 120 130 140 150 160 170 180 190 200 210 220 pF1KB6 HAFDIFQMLDVLQELRGTVAQQVTGSSGTVKVVVVDSVTAVV----SPLLGGQQREGLAL : . . .:::... .. ... :.: .:.:..:::..:: . : :. .: . NP_598 HLYRELTCDEVLQRIE-SLEEEII-SKG-IKLVILDSVASVVRKEFDAQLQGNLKERNKF 180 190 200 210 220 230 230 240 250 260 pF1KB6 MMQLARELKTLARDLGMAVVVTNHITRDRDSGRL-------KPA---------------- . . : :: ::..... :..::.:: . :: : .:: NP_598 LAREASSLKYLAEEFSIPVILTNQITT-HLSGALASQADLVSPADDLSLSEGTSGSSCVI 240 250 260 270 280 290 270 280 290 300 310 320 pF1KB6 --LGRSWSFVPSTRILLDTIEGAGASGGRRMACLAKSSRQPTGFQEMVDIGTWGTSEQSA :: .:: .::..:. ... ::. .::: : : .: . .:.. NP_598 AALGNTWSHSVNTRLILQYLDSE-----RRQILIAKSPLAP--FTSFV----YTIKEEGL 300 310 320 330 340 pF1KB6 TLQGDQT .:::.. NP_598 VLQGQEKP 350 >>NP_001308741 (OMIM: 602948) DNA repair protein RAD51 h (351 aa) initn: 257 init1: 131 opt: 311 Z-score: 369.9 bits: 76.8 E(85289): 7.3e-14 Smith-Waterman score: 325; 28.1% identity (57.6% similar) in 356 aa overlap (11-327:10-348) 10 20 30 40 50 60 pF1KB6 MGVLRVGLCPGLTEEMIQLLRSHRIKTVVDLVSADLEEVAQKCGLSYKALVALRRVLLAQ ::..:. . : :.: : :.. . :. . ::::... : .... NP_001 MGSKKLKRVGLSQELCDRLSRHQILTCQDFLCLSPLELMKVTGLSYRGVHELL-CMVSR 10 20 30 40 50 70 80 90 100 110 pF1KB6 FSAFPVNGADLYEELKT---STAILSTGIGSLDKLLDAGLYTGEVTEIVGGPGSGKTQVC : .. : . .. : :.::: ...::. : .:. : .:::.: :: :::: : NP_001 ACAPKMQTAYGIKAQRSADFSPAFLSTTLSALDEALHGGVACGSLTEITGPPGCGKTQFC 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 LCMA------ANVAHGLQQNVLYVDSNGGLTASRLLQLLQAKTQDEEEQAEALRRIQV-V . :. .:.. ::. :.:.:......: ::... ... . : : . : NP_001 IMMSILATLPTNMG-GLEGAVVYIDTESAFSAERLVEIAESRFPRYFNTEEKLLLTSSKV 120 130 140 150 160 170 180 190 200 210 220 pF1KB6 HAFDIFQMLDVLQELRGTVAQQVTGSSGTVKVVVVDSVTAVV----SPLLGGQQREGLAL : . . .:::... .. ... :.: .:.:..:::..:: . : :. .: . NP_001 HLYRELTCDEVLQRIE-SLEEEII-SKG-IKLVILDSVASVVRKEFDAQLQGNLKERNKF 180 190 200 210 220 230 230 240 250 260 pF1KB6 MMQLARELKTLARDLGMAVVVTNHITRDRDSGRL-------KPA---------------- . . : :: ::..... :..::.:: . :: : .:: NP_001 LAREASSLKYLAEEFSIPVILTNQITT-HLSGALASQADLVSPADDLSLSEGTSGSSCVI 240 250 260 270 280 290 270 280 290 300 310 320 pF1KB6 --LGRSWSFVPSTRILLDTIEGAGASGGRRMACLAKSSRQPTGFQEMVDIGTWGTSEQSA :: .:: .::..:. ... ::. .::: : : .: . .:.. NP_001 AALGNTWSHSVNTRLILQYLDSE-----RRQILIAKSPLAP--FTSFV----YTIKEEGL 300 310 320 330 340 pF1KB6 TLQGDQT .:::.. NP_001 VLQGSREFK 350 328 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 21:00:25 2016 done: Fri Nov 4 21:00:26 2016 Total Scan time: 7.890 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]