FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6486, 356 aa 1>>>pF1KB6486 356 - 356 aa - 356 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.6613+/-0.000826; mu= 9.7002+/- 0.049 mean_var=83.3825+/-17.673, 0's: 0 Z-trim(108.3): 17 B-trim: 1028 in 2/50 Lambda= 0.140455 statistics sampled from 10106 (10117) to 10106 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.687), E-opt: 0.2 (0.311), width: 16 Scan time: 2.830 The best scores are: opt bits E(32554) CCDS47956.1 APTX gene_id:54840|Hs108|chr9 ( 342) 2322 480.1 1.2e-135 CCDS6532.1 APTX gene_id:54840|Hs108|chr9 ( 306) 2061 427.2 9e-120 CCDS75827.1 APTX gene_id:54840|Hs108|chr9 ( 288) 1669 347.8 6.9e-96 CCDS56568.1 APTX gene_id:54840|Hs108|chr9 ( 302) 1669 347.8 7.2e-96 >>CCDS47956.1 APTX gene_id:54840|Hs108|chr9 (342 aa) initn: 2322 init1: 2322 opt: 2322 Z-score: 2548.8 bits: 480.1 E(32554): 1.2e-135 Smith-Waterman score: 2322; 100.0% identity (100.0% similar) in 342 aa overlap (15-356:1-342) 10 20 30 40 50 60 pF1KB6 MSNVNLSVSDFWRVMMRVCWLVRQDSRHQRIRLPHLEAVVIGRGPETKITDKKCSRQQVQ :::::::::::::::::::::::::::::::::::::::::::::: CCDS47 MMRVCWLVRQDSRHQRIRLPHLEAVVIGRGPETKITDKKCSRQQVQ 10 20 30 40 70 80 90 100 110 120 pF1KB6 LKAECNKGYVKVKQVGVNPTSIDSVVIGKDQEVKLQPGQVLHMVNELYPYIVEFEEEAKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 LKAECNKGYVKVKQVGVNPTSIDSVVIGKDQEVKLQPGQVLHMVNELYPYIVEFEEEAKN 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB6 PGLETHRKRKRSGNSDSIERDAAQEAEAGTGLEPGSNSGQCSVPLKKGKDAPIKKESLGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 PGLETHRKRKRSGNSDSIERDAAQEAEAGTGLEPGSNSGQCSVPLKKGKDAPIKKESLGH 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB6 WSQGLKISMQDPKMQVYKDEQVVVIKDKYPKARYHWLVLPWTSISSLKAVAREHLELLKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 WSQGLKISMQDPKMQVYKDEQVVVIKDKYPKARYHWLVLPWTSISSLKAVAREHLELLKH 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB6 MHTVGEKVIVDFAGSSKLRFRLGYHAIPSMSHVHLHVISQDFDSPCLKNKKHWNSFNTEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 MHTVGEKVIVDFAGSSKLRFRLGYHAIPSMSHVHLHVISQDFDSPCLKNKKHWNSFNTEY 230 240 250 260 270 280 310 320 330 340 350 pF1KB6 FLESQAVIEMVQEAGRVTVRDGMPELLKLPLRCHECQQLLPSIPQLKEHLRKHWTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS47 FLESQAVIEMVQEAGRVTVRDGMPELLKLPLRCHECQQLLPSIPQLKEHLRKHWTQ 290 300 310 320 330 340 >>CCDS6532.1 APTX gene_id:54840|Hs108|chr9 (306 aa) initn: 2061 init1: 2061 opt: 2061 Z-score: 2263.8 bits: 427.2 E(32554): 9e-120 Smith-Waterman score: 2061; 100.0% identity (100.0% similar) in 305 aa overlap (1-305:1-305) 10 20 30 40 50 60 pF1KB6 MSNVNLSVSDFWRVMMRVCWLVRQDSRHQRIRLPHLEAVVIGRGPETKITDKKCSRQQVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS65 MSNVNLSVSDFWRVMMRVCWLVRQDSRHQRIRLPHLEAVVIGRGPETKITDKKCSRQQVQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 LKAECNKGYVKVKQVGVNPTSIDSVVIGKDQEVKLQPGQVLHMVNELYPYIVEFEEEAKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS65 LKAECNKGYVKVKQVGVNPTSIDSVVIGKDQEVKLQPGQVLHMVNELYPYIVEFEEEAKN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 PGLETHRKRKRSGNSDSIERDAAQEAEAGTGLEPGSNSGQCSVPLKKGKDAPIKKESLGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS65 PGLETHRKRKRSGNSDSIERDAAQEAEAGTGLEPGSNSGQCSVPLKKGKDAPIKKESLGH 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 WSQGLKISMQDPKMQVYKDEQVVVIKDKYPKARYHWLVLPWTSISSLKAVAREHLELLKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS65 WSQGLKISMQDPKMQVYKDEQVVVIKDKYPKARYHWLVLPWTSISSLKAVAREHLELLKH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 MHTVGEKVIVDFAGSSKLRFRLGYHAIPSMSHVHLHVISQDFDSPCLKNKKHWNSFNTEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS65 MHTVGEKVIVDFAGSSKLRFRLGYHAIPSMSHVHLHVISQDFDSPCLKNKKHWNSFNTEY 250 260 270 280 290 300 310 320 330 340 350 pF1KB6 FLESQAVIEMVQEAGRVTVRDGMPELLKLPLRCHECQQLLPSIPQLKEHLRKHWTQ ::::: CCDS65 FLESQE >>CCDS75827.1 APTX gene_id:54840|Hs108|chr9 (288 aa) initn: 1956 init1: 1661 opt: 1669 Z-score: 1834.9 bits: 347.8 E(32554): 6.9e-96 Smith-Waterman score: 1852; 84.2% identity (84.2% similar) in 342 aa overlap (15-356:1-288) 10 20 30 40 50 60 pF1KB6 MSNVNLSVSDFWRVMMRVCWLVRQDSRHQRIRLPHLEAVVIGRGPETKITDKKCSRQQVQ :::::::::::::::::::::::::::::::::::::::::::: CCDS75 MMRVCWLVRQDSRHQRIRLPHLEAVVIGRGPETKITDKKCSRQQ-- 10 20 30 40 70 80 90 100 110 120 pF1KB6 LKAECNKGYVKVKQVGVNPTSIDSVVIGKDQEVKLQPGQVLHMVNELYPYIVEFEEEAKN :::::::: CCDS75 ----------------------------------------------------EFEEEAKN 50 130 140 150 160 170 180 pF1KB6 PGLETHRKRKRSGNSDSIERDAAQEAEAGTGLEPGSNSGQCSVPLKKGKDAPIKKESLGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 PGLETHRKRKRSGNSDSIERDAAQEAEAGTGLEPGSNSGQCSVPLKKGKDAPIKKESLGH 60 70 80 90 100 110 190 200 210 220 230 240 pF1KB6 WSQGLKISMQDPKMQVYKDEQVVVIKDKYPKARYHWLVLPWTSISSLKAVAREHLELLKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 WSQGLKISMQDPKMQVYKDEQVVVIKDKYPKARYHWLVLPWTSISSLKAVAREHLELLKH 120 130 140 150 160 170 250 260 270 280 290 300 pF1KB6 MHTVGEKVIVDFAGSSKLRFRLGYHAIPSMSHVHLHVISQDFDSPCLKNKKHWNSFNTEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 MHTVGEKVIVDFAGSSKLRFRLGYHAIPSMSHVHLHVISQDFDSPCLKNKKHWNSFNTEY 180 190 200 210 220 230 310 320 330 340 350 pF1KB6 FLESQAVIEMVQEAGRVTVRDGMPELLKLPLRCHECQQLLPSIPQLKEHLRKHWTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 FLESQAVIEMVQEAGRVTVRDGMPELLKLPLRCHECQQLLPSIPQLKEHLRKHWTQ 240 250 260 270 280 >>CCDS56568.1 APTX gene_id:54840|Hs108|chr9 (302 aa) initn: 2050 init1: 1661 opt: 1669 Z-score: 1834.6 bits: 347.8 E(32554): 7.2e-96 Smith-Waterman score: 1946; 84.8% identity (84.8% similar) in 356 aa overlap (1-356:1-302) 10 20 30 40 50 60 pF1KB6 MSNVNLSVSDFWRVMMRVCWLVRQDSRHQRIRLPHLEAVVIGRGPETKITDKKCSRQQVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 MSNVNLSVSDFWRVMMRVCWLVRQDSRHQRIRLPHLEAVVIGRGPETKITDKKCSRQQ-- 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 LKAECNKGYVKVKQVGVNPTSIDSVVIGKDQEVKLQPGQVLHMVNELYPYIVEFEEEAKN :::::::: CCDS56 ----------------------------------------------------EFEEEAKN 60 130 140 150 160 170 180 pF1KB6 PGLETHRKRKRSGNSDSIERDAAQEAEAGTGLEPGSNSGQCSVPLKKGKDAPIKKESLGH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 PGLETHRKRKRSGNSDSIERDAAQEAEAGTGLEPGSNSGQCSVPLKKGKDAPIKKESLGH 70 80 90 100 110 120 190 200 210 220 230 240 pF1KB6 WSQGLKISMQDPKMQVYKDEQVVVIKDKYPKARYHWLVLPWTSISSLKAVAREHLELLKH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 WSQGLKISMQDPKMQVYKDEQVVVIKDKYPKARYHWLVLPWTSISSLKAVAREHLELLKH 130 140 150 160 170 180 250 260 270 280 290 300 pF1KB6 MHTVGEKVIVDFAGSSKLRFRLGYHAIPSMSHVHLHVISQDFDSPCLKNKKHWNSFNTEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 MHTVGEKVIVDFAGSSKLRFRLGYHAIPSMSHVHLHVISQDFDSPCLKNKKHWNSFNTEY 190 200 210 220 230 240 310 320 330 340 350 pF1KB6 FLESQAVIEMVQEAGRVTVRDGMPELLKLPLRCHECQQLLPSIPQLKEHLRKHWTQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS56 FLESQAVIEMVQEAGRVTVRDGMPELLKLPLRCHECQQLLPSIPQLKEHLRKHWTQ 250 260 270 280 290 300 356 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 04:07:53 2016 done: Sat Nov 5 04:07:53 2016 Total Scan time: 2.830 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]