FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6487, 329 aa 1>>>pF1KB6487 329 - 329 aa - 329 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.8158+/-0.00069; mu= 15.2524+/- 0.042 mean_var=85.7786+/-17.484, 0's: 0 Z-trim(111.9): 30 B-trim: 490 in 1/52 Lambda= 0.138479 statistics sampled from 12731 (12761) to 12731 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.743), E-opt: 0.2 (0.392), width: 16 Scan time: 2.480 The best scores are: opt bits E(32554) CCDS10661.1 KCTD13 gene_id:253980|Hs108|chr16 ( 329) 2182 445.1 3.7e-125 CCDS9128.1 KCTD10 gene_id:83892|Hs108|chr12 ( 313) 1418 292.4 3.2e-79 CCDS11227.1 TNFAIP1 gene_id:7126|Hs108|chr17 ( 316) 1356 280.0 1.7e-75 >>CCDS10661.1 KCTD13 gene_id:253980|Hs108|chr16 (329 aa) initn: 2182 init1: 2182 opt: 2182 Z-score: 2360.4 bits: 445.1 E(32554): 3.7e-125 Smith-Waterman score: 2182; 100.0% identity (100.0% similar) in 329 aa overlap (1-329:1-329) 10 20 30 40 50 60 pF1KB6 MSAEASGPAAAAAPSLEAPKPSGLEPGPAAYGLKPLTPNSKYVKLNVGGSLHYTTLRTLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 MSAEASGPAAAAAPSLEAPKPSGLEPGPAAYGLKPLTPNSKYVKLNVGGSLHYTTLRTLT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 GQDTMLKAMFSGRVEVLTDAGGWVLIDRSGRHFGTILNYLRDGSVPLPESTRELGELLGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 GQDTMLKAMFSGRVEVLTDAGGWVLIDRSGRHFGTILNYLRDGSVPLPESTRELGELLGE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 ARYYLVQGLIEDCQLALQQKRETLSPLCLIPMVTSPREEQQLLASTSKPVVKLLHNRSNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 ARYYLVQGLIEDCQLALQQKRETLSPLCLIPMVTSPREEQQLLASTSKPVVKLLHNRSNN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 KYSYTSTSDDNLLKNIELFDKLALRFHGRLLFLKDVLGDEICCWSFYGQGRKIAEVCCTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 KYSYTSTSDDNLLKNIELFDKLALRFHGRLLFLKDVLGDEICCWSFYGQGRKIAEVCCTS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 IVYATEKKQTKVEFPEARIFEETLNILIYETPRGPDPALLEATGGAAGAGGAGRGEDEEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS10 IVYATEKKQTKVEFPEARIFEETLNILIYETPRGPDPALLEATGGAAGAGGAGRGEDEEN 250 260 270 280 290 300 310 320 pF1KB6 REHRVRRIHVRRHITHDERPHGQQIVFKD ::::::::::::::::::::::::::::: CCDS10 REHRVRRIHVRRHITHDERPHGQQIVFKD 310 320 >>CCDS9128.1 KCTD10 gene_id:83892|Hs108|chr12 (313 aa) initn: 898 init1: 763 opt: 1418 Z-score: 1535.8 bits: 292.4 E(32554): 3.2e-79 Smith-Waterman score: 1418; 72.4% identity (89.8% similar) in 294 aa overlap (33-324:24-313) 10 20 30 40 50 60 pF1KB6 AEASGPAAAAAPSLEAPKPSGLEPGPAAYGLKPLTPNSKYVKLNVGGSLHYTTLRTLTGQ .: .:.::::::::::.:.:::..::: : CCDS91 MEEMSGESVVSSAVPAAATRTTSFKGTSPSSKYVKLNVGGALYYTTMQTLTKQ 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 DTMLKAMFSGRVEVLTDAGGWVLIDRSGRHFGTILNYLRDGSVPLPESTRELGELLGEAR :::::::::::.:::::. ::.:::: :.::::::::::::.:::::: ::. :::.::. CCDS91 DTMLKAMFSGRMEVLTDSEGWILIDRCGKHFGTILNYLRDGAVPLPESRREIEELLAEAK 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 YYLVQGLIEDCQLALQQKRETLSPLCLIPMVTSPREEQQLLASTSKPVVKLLHNRSNNKY :::::::.:.:: :::.: .: :.: .:..:: .:::.:.:...::.::::.::::::: CCDS91 YYLVQGLVEECQAALQNK-DTYEPFCKVPVITSSKEEQKLIATSNKPAVKLLYNRSNNKY 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB6 SYTSTSDDNLLKNIELFDKLALRFHGRLLFLKDVLGDEICCWSFYGQGRKIAEVCCTSIV ::::.::::.::::::::::.:::.::.::.:::.::::::::::::::::::::::::: CCDS91 SYTSNSDDNMLKNIELFDKLSLRFNGRVLFIKDVIGDEICCWSFYGQGRKIAEVCCTSIV 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB6 YATEKKQTKVEFPEARIFEETLNILIYETP--RGPDPALLEATGGAAGAGGAGRGEDEEN :::::::::::::::::.:::::::.::. :::: ::::::::::: . ..:.. CCDS91 YATEKKQTKVEFPEARIYEETLNILLYEAQDGRGPDNALLEATGGAAGRSHHLDEDEERE 240 250 260 270 280 290 310 320 pF1KB6 REHRVRRIHVRRHITHDERPHGQQIVFKD : .::::::..: :.: : .: CCDS91 RIERVRRIHIKRP---DDRAHLHQ 300 310 >>CCDS11227.1 TNFAIP1 gene_id:7126|Hs108|chr17 (316 aa) initn: 1389 init1: 1343 opt: 1356 Z-score: 1468.8 bits: 280.0 E(32554): 1.7e-75 Smith-Waterman score: 1361; 64.4% identity (84.4% similar) in 326 aa overlap (6-329:2-316) 10 20 30 40 50 60 pF1KB6 MSAEASGPAAAAAPSLEAPKPSGLEPGPAAYGLKPLTPNSKYVKLNVGGSLHYTTLRTLT :: . : :: ::.. : :: ..:::.:::::::.:::.:.:: CCDS11 MSGDTCLCPASGAKPKLSGFKGG----GL-----GNKYVQLNVGGSLYYTTVRALT 10 20 30 40 70 80 90 100 110 120 pF1KB6 GQDTMLKAMFSGRVEVLTDAGGWVLIDRSGRHFGTILNYLRDGSVPLPESTRELGELLGE .:::::::::::.::::: ::.:::: :.::::::::::: .. ::.. .:. ::..: CCDS11 RHDTMLKAMFSGRMEVLTDKEGWILIDRCGKHFGTILNYLRDDTITLPQNRQEIKELMAE 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB6 ARYYLVQGLIEDCQLALQQKRETLSPLCLIPMVTSPREEQQLLASTSKPVVKLLHNRSNN :.:::.:::.. :: :::.:... .:.: ::..:: .::..:. :..:::::::.::::: CCDS11 AKYYLIQGLVNMCQSALQDKKDSYQPVCNIPIITSLKEEERLIESSTKPVVKLLYNRSNN 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB6 KYSYTSTSDDNLLKNIELFDKLALRFHGRLLFLKDVLGDEICCWSFYGQGRKIAEVCCTS ::::::.:::.:::::::::::.:::.::.::.:::.:::::::::::::::.::::::: CCDS11 KYSYTSNSDDHLLKNIELFDKLSLRFNGRVLFIKDVIGDEICCWSFYGQGRKLAEVCCTS 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB6 IVYATEKKQTKVEFPEARIFEETLNILIYETPRGPDPALLEATGGAAGAGGAGRGEDEEN :::::::::::::::::::.:::::.:.::::: :: .::::: . . . :. .::::. CCDS11 IVYATEKKQTKVEFPEARIYEETLNVLLYETPRVPDNSLLEAT--SRSRSQASPSEDEET 230 240 250 260 270 280 310 320 pF1KB6 RE--HRVRRIHVRRHITHDERPHGQQIVFKD : :::::::.:. :.:.: :.: . .: CCDS11 FELRDRVRRIHVKRYSTYDDRQLGHQSTHRD 290 300 310 329 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 23:08:04 2016 done: Fri Nov 4 23:08:04 2016 Total Scan time: 2.480 Total Display time: -0.010 Function used was FASTA [36.3.4 Apr, 2011]