FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6487, 329 aa 1>>>pF1KB6487 329 - 329 aa - 329 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.5190+/-0.000296; mu= 16.8496+/- 0.019 mean_var=86.6660+/-17.422, 0's: 0 Z-trim(118.7): 55 B-trim: 0 in 0/59 Lambda= 0.137768 statistics sampled from 31826 (31881) to 31826 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.735), E-opt: 0.2 (0.374), width: 16 Scan time: 7.540 The best scores are: opt bits E(85289) NP_849194 (OMIM: 608947) BTB/POZ domain-containing ( 329) 2182 443.0 4.2e-124 NP_001304324 (OMIM: 613421) BTB/POZ domain-contain ( 314) 1434 294.3 2.3e-79 NP_114160 (OMIM: 613421) BTB/POZ domain-containing ( 313) 1418 291.1 2.1e-78 NP_066960 (OMIM: 191161) BTB/POZ domain-containing ( 316) 1356 278.8 1.1e-74 XP_011544085 (OMIM: 608947) PREDICTED: BTB/POZ dom ( 347) 1304 268.5 1.5e-71 XP_011544086 (OMIM: 608947) PREDICTED: BTB/POZ dom ( 202) 1289 265.3 7.8e-71 XP_016878593 (OMIM: 608947) PREDICTED: BTB/POZ dom ( 178) 1190 245.6 5.9e-65 XP_016880482 (OMIM: 191161) PREDICTED: BTB/POZ dom ( 391) 1095 227.0 5.2e-59 XP_016878594 (OMIM: 608947) PREDICTED: BTB/POZ dom ( 175) 906 189.1 5.7e-48 XP_016878595 (OMIM: 608947) PREDICTED: BTB/POZ dom ( 173) 903 188.5 8.6e-48 NP_001304328 (OMIM: 613421) BTB/POZ domain-contain ( 290) 744 157.1 4.2e-38 NP_001161433 (OMIM: 611725,611726) BTB/POZ domain- ( 288) 262 61.3 2.9e-09 NP_694578 (OMIM: 611725,611726) BTB/POZ domain-con ( 289) 262 61.3 2.9e-09 NP_001269615 (OMIM: 616386,616398) BTB/POZ domain- ( 220) 208 50.5 4e-06 NP_001269614 (OMIM: 616386,616398) BTB/POZ domain- ( 225) 208 50.5 4e-06 XP_011528679 (OMIM: 616386,616398) PREDICTED: BTB/ ( 249) 208 50.5 4.3e-06 NP_076981 (OMIM: 615240) BTB/POZ domain-containing ( 234) 207 50.3 4.8e-06 NP_078957 (OMIM: 616386,616398) BTB/POZ domain-con ( 297) 208 50.6 5e-06 XP_005261801 (OMIM: 616386,616398) PREDICTED: BTB/ ( 315) 208 50.6 5.2e-06 NP_001269613 (OMIM: 616386,616398) BTB/POZ domain- ( 321) 208 50.6 5.3e-06 XP_005261800 (OMIM: 616386,616398) PREDICTED: BTB/ ( 328) 208 50.6 5.4e-06 XP_005261798 (OMIM: 616386,616398) PREDICTED: BTB/ ( 352) 208 50.6 5.7e-06 XP_005261799 (OMIM: 616386,616398) PREDICTED: BTB/ ( 352) 208 50.6 5.7e-06 XP_011528676 (OMIM: 616386,616398) PREDICTED: BTB/ ( 370) 208 50.7 5.9e-06 NP_001123467 (OMIM: 615240) BTB/POZ domain-contain ( 283) 206 50.2 6.3e-06 XP_011525599 (OMIM: 615240) PREDICTED: BTB/POZ dom ( 283) 206 50.2 6.3e-06 XP_016882772 (OMIM: 615240) PREDICTED: BTB/POZ dom ( 283) 206 50.2 6.3e-06 NP_001123466 (OMIM: 615240) BTB/POZ domain-contain ( 283) 206 50.2 6.3e-06 XP_011525600 (OMIM: 615240) PREDICTED: BTB/POZ dom ( 283) 206 50.2 6.3e-06 XP_011522877 (OMIM: 613422) PREDICTED: BTB/POZ dom ( 226) 191 47.1 4.2e-05 NP_056168 (OMIM: 613422) BTB/POZ domain-containing ( 263) 191 47.2 4.7e-05 XP_011535975 (OMIM: 613423) PREDICTED: BTB/POZ dom ( 286) 182 45.4 0.00017 XP_011535974 (OMIM: 613423) PREDICTED: BTB/POZ dom ( 304) 182 45.4 0.00018 XP_005268549 (OMIM: 613423) PREDICTED: BTB/POZ dom ( 428) 182 45.5 0.00024 XP_011535973 (OMIM: 613423) PREDICTED: BTB/POZ dom ( 428) 182 45.5 0.00024 XP_006714852 (OMIM: 613423) PREDICTED: BTB/POZ dom ( 428) 182 45.5 0.00024 NP_065819 (OMIM: 613423) BTB/POZ domain-containing ( 428) 182 45.5 0.00024 XP_005268550 (OMIM: 613423) PREDICTED: BTB/POZ dom ( 428) 182 45.5 0.00024 NP_001245150 (OMIM: 181270,613420) BTB/POZ domain- ( 257) 179 44.8 0.00024 NP_945342 (OMIM: 181270,613420) BTB/POZ domain-con ( 257) 179 44.8 0.00024 NP_001129677 (OMIM: 181270,613420) BTB/POZ domain- ( 257) 179 44.8 0.00024 XP_016881197 (OMIM: 181270,613420) PREDICTED: BTB/ ( 257) 179 44.8 0.00024 NP_001245151 (OMIM: 181270,613420) BTB/POZ domain- ( 265) 179 44.8 0.00025 NP_061865 (OMIM: 611285) BTB/POZ domain-containing ( 234) 175 43.9 0.00039 NP_001136202 (OMIM: 181270,613420) BTB/POZ domain- ( 865) 179 45.2 0.00061 NP_612453 (OMIM: 610521) BTB/POZ domain-containing ( 325) 164 41.9 0.0023 NP_955751 (OMIM: 607947) potassium channel regulat ( 229) 161 41.1 0.0026 NP_775876 (OMIM: 607947) potassium channel regulat ( 272) 161 41.2 0.003 NP_001306223 (OMIM: 613272) BTB/POZ domain-contain ( 813) 160 41.4 0.008 NP_057205 (OMIM: 613272) BTB/POZ domain-containing ( 815) 160 41.4 0.008 >>NP_849194 (OMIM: 608947) BTB/POZ domain-containing ada (329 aa) initn: 2182 init1: 2182 opt: 2182 Z-score: 2349.1 bits: 443.0 E(85289): 4.2e-124 Smith-Waterman score: 2182; 100.0% identity (100.0% similar) in 329 aa overlap (1-329:1-329) 10 20 30 40 50 60 pF1KB6 MSAEASGPAAAAAPSLEAPKPSGLEPGPAAYGLKPLTPNSKYVKLNVGGSLHYTTLRTLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_849 MSAEASGPAAAAAPSLEAPKPSGLEPGPAAYGLKPLTPNSKYVKLNVGGSLHYTTLRTLT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 GQDTMLKAMFSGRVEVLTDAGGWVLIDRSGRHFGTILNYLRDGSVPLPESTRELGELLGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_849 GQDTMLKAMFSGRVEVLTDAGGWVLIDRSGRHFGTILNYLRDGSVPLPESTRELGELLGE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 ARYYLVQGLIEDCQLALQQKRETLSPLCLIPMVTSPREEQQLLASTSKPVVKLLHNRSNN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_849 ARYYLVQGLIEDCQLALQQKRETLSPLCLIPMVTSPREEQQLLASTSKPVVKLLHNRSNN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 KYSYTSTSDDNLLKNIELFDKLALRFHGRLLFLKDVLGDEICCWSFYGQGRKIAEVCCTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_849 KYSYTSTSDDNLLKNIELFDKLALRFHGRLLFLKDVLGDEICCWSFYGQGRKIAEVCCTS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 IVYATEKKQTKVEFPEARIFEETLNILIYETPRGPDPALLEATGGAAGAGGAGRGEDEEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_849 IVYATEKKQTKVEFPEARIFEETLNILIYETPRGPDPALLEATGGAAGAGGAGRGEDEEN 250 260 270 280 290 300 310 320 pF1KB6 REHRVRRIHVRRHITHDERPHGQQIVFKD ::::::::::::::::::::::::::::: NP_849 REHRVRRIHVRRHITHDERPHGQQIVFKD 310 320 >>NP_001304324 (OMIM: 613421) BTB/POZ domain-containing (314 aa) initn: 1448 init1: 1313 opt: 1434 Z-score: 1545.9 bits: 294.3 E(85289): 2.3e-79 Smith-Waterman score: 1434; 72.4% identity (90.1% similar) in 294 aa overlap (33-324:24-314) 10 20 30 40 50 60 pF1KB6 AEASGPAAAAAPSLEAPKPSGLEPGPAAYGLKPLTPNSKYVKLNVGGSLHYTTLRTLTGQ .: .:.::::::::::.:.:::..::: : NP_001 MEEMSGESVVSSAVPAAATRTTSFKGTSPSSKYVKLNVGGALYYTTMQTLTKQ 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 DTMLKAMFSGRVEVLTDAGGWVLIDRSGRHFGTILNYLRDGSVPLPESTRELGELLGEAR :::::::::::.:::::. ::.:::: :.::::::::::::.:::::: ::. :::.::. NP_001 DTMLKAMFSGRMEVLTDSEGWILIDRCGKHFGTILNYLRDGAVPLPESRREIEELLAEAK 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 YYLVQGLIEDCQLALQQKRETLSPLCLIPMVTSPREEQQLLASTSKPVVKLLHNRSNNKY :::::::.:.:: ::::...: :.: .:..:: .:::.:.:...::.::::.::::::: NP_001 YYLVQGLVEECQAALQQNKDTYEPFCKVPVITSSKEEQKLIATSNKPAVKLLYNRSNNKY 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB6 SYTSTSDDNLLKNIELFDKLALRFHGRLLFLKDVLGDEICCWSFYGQGRKIAEVCCTSIV ::::.::::.::::::::::.:::.::.::.:::.::::::::::::::::::::::::: NP_001 SYTSNSDDNMLKNIELFDKLSLRFNGRVLFIKDVIGDEICCWSFYGQGRKIAEVCCTSIV 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB6 YATEKKQTKVEFPEARIFEETLNILIYETP--RGPDPALLEATGGAAGAGGAGRGEDEEN :::::::::::::::::.:::::::.::. :::: ::::::::::: . ..:.. NP_001 YATEKKQTKVEFPEARIYEETLNILLYEAQDGRGPDNALLEATGGAAGRSHHLDEDEERE 240 250 260 270 280 290 310 320 pF1KB6 REHRVRRIHVRRHITHDERPHGQQIVFKD : .::::::..: :.: : .: NP_001 RIERVRRIHIKRP---DDRAHLHQ 300 310 >>NP_114160 (OMIM: 613421) BTB/POZ domain-containing ada (313 aa) initn: 898 init1: 763 opt: 1418 Z-score: 1528.7 bits: 291.1 E(85289): 2.1e-78 Smith-Waterman score: 1418; 72.4% identity (89.8% similar) in 294 aa overlap (33-324:24-313) 10 20 30 40 50 60 pF1KB6 AEASGPAAAAAPSLEAPKPSGLEPGPAAYGLKPLTPNSKYVKLNVGGSLHYTTLRTLTGQ .: .:.::::::::::.:.:::..::: : NP_114 MEEMSGESVVSSAVPAAATRTTSFKGTSPSSKYVKLNVGGALYYTTMQTLTKQ 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 DTMLKAMFSGRVEVLTDAGGWVLIDRSGRHFGTILNYLRDGSVPLPESTRELGELLGEAR :::::::::::.:::::. ::.:::: :.::::::::::::.:::::: ::. :::.::. NP_114 DTMLKAMFSGRMEVLTDSEGWILIDRCGKHFGTILNYLRDGAVPLPESRREIEELLAEAK 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 YYLVQGLIEDCQLALQQKRETLSPLCLIPMVTSPREEQQLLASTSKPVVKLLHNRSNNKY :::::::.:.:: :::.: .: :.: .:..:: .:::.:.:...::.::::.::::::: NP_114 YYLVQGLVEECQAALQNK-DTYEPFCKVPVITSSKEEQKLIATSNKPAVKLLYNRSNNKY 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB6 SYTSTSDDNLLKNIELFDKLALRFHGRLLFLKDVLGDEICCWSFYGQGRKIAEVCCTSIV ::::.::::.::::::::::.:::.::.::.:::.::::::::::::::::::::::::: NP_114 SYTSNSDDNMLKNIELFDKLSLRFNGRVLFIKDVIGDEICCWSFYGQGRKIAEVCCTSIV 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB6 YATEKKQTKVEFPEARIFEETLNILIYETP--RGPDPALLEATGGAAGAGGAGRGEDEEN :::::::::::::::::.:::::::.::. :::: ::::::::::: . ..:.. NP_114 YATEKKQTKVEFPEARIYEETLNILLYEAQDGRGPDNALLEATGGAAGRSHHLDEDEERE 240 250 260 270 280 290 310 320 pF1KB6 REHRVRRIHVRRHITHDERPHGQQIVFKD : .::::::..: :.: : .: NP_114 RIERVRRIHIKRP---DDRAHLHQ 300 310 >>NP_066960 (OMIM: 191161) BTB/POZ domain-containing ada (316 aa) initn: 1389 init1: 1343 opt: 1356 Z-score: 1462.0 bits: 278.8 E(85289): 1.1e-74 Smith-Waterman score: 1361; 64.4% identity (84.4% similar) in 326 aa overlap (6-329:2-316) 10 20 30 40 50 60 pF1KB6 MSAEASGPAAAAAPSLEAPKPSGLEPGPAAYGLKPLTPNSKYVKLNVGGSLHYTTLRTLT :: . : :: ::.. : :: ..:::.:::::::.:::.:.:: NP_066 MSGDTCLCPASGAKPKLSGFKGG----GL-----GNKYVQLNVGGSLYYTTVRALT 10 20 30 40 70 80 90 100 110 120 pF1KB6 GQDTMLKAMFSGRVEVLTDAGGWVLIDRSGRHFGTILNYLRDGSVPLPESTRELGELLGE .:::::::::::.::::: ::.:::: :.::::::::::: .. ::.. .:. ::..: NP_066 RHDTMLKAMFSGRMEVLTDKEGWILIDRCGKHFGTILNYLRDDTITLPQNRQEIKELMAE 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB6 ARYYLVQGLIEDCQLALQQKRETLSPLCLIPMVTSPREEQQLLASTSKPVVKLLHNRSNN :.:::.:::.. :: :::.:... .:.: ::..:: .::..:. :..:::::::.::::: NP_066 AKYYLIQGLVNMCQSALQDKKDSYQPVCNIPIITSLKEEERLIESSTKPVVKLLYNRSNN 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB6 KYSYTSTSDDNLLKNIELFDKLALRFHGRLLFLKDVLGDEICCWSFYGQGRKIAEVCCTS ::::::.:::.:::::::::::.:::.::.::.:::.:::::::::::::::.::::::: NP_066 KYSYTSNSDDHLLKNIELFDKLSLRFNGRVLFIKDVIGDEICCWSFYGQGRKLAEVCCTS 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB6 IVYATEKKQTKVEFPEARIFEETLNILIYETPRGPDPALLEATGGAAGAGGAGRGEDEEN :::::::::::::::::::.:::::.:.::::: :: .::::: . . . :. .::::. NP_066 IVYATEKKQTKVEFPEARIYEETLNVLLYETPRVPDNSLLEAT--SRSRSQASPSEDEET 230 240 250 260 270 280 310 320 pF1KB6 RE--HRVRRIHVRRHITHDERPHGQQIVFKD : :::::::.:. :.:.: :.: . .: NP_066 FELRDRVRRIHVKRYSTYDDRQLGHQSTHRD 290 300 310 >>XP_011544085 (OMIM: 608947) PREDICTED: BTB/POZ domain- (347 aa) initn: 1289 init1: 1289 opt: 1304 Z-score: 1405.6 bits: 268.5 E(85289): 1.5e-71 Smith-Waterman score: 2136; 94.8% identity (94.8% similar) in 347 aa overlap (1-329:1-347) 10 20 30 40 50 60 pF1KB6 MSAEASGPAAAAAPSLEAPKPSGLEPGPAAYGLKPLTPNSKYVKLNVGGSLHYTTLRTLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MSAEASGPAAAAAPSLEAPKPSGLEPGPAAYGLKPLTPNSKYVKLNVGGSLHYTTLRTLT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 GQDTMLKAMFSGRVEVLTDAGGWVLIDRSGRHFGTILNYLRDGSVPLPESTRELGELLGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GQDTMLKAMFSGRVEVLTDAGGWVLIDRSGRHFGTILNYLRDGSVPLPESTRELGELLGE 70 80 90 100 110 120 130 140 150 160 pF1KB6 ARYYLVQGLIEDCQLALQ------------------QKRETLSPLCLIPMVTSPREEQQL :::::::::::::::::: :::::::::::::::::::::::: XP_011 ARYYLVQGLIEDCQLALQVRAFGVPMPMFLGELPKQQKRETLSPLCLIPMVTSPREEQQL 130 140 150 160 170 180 170 180 190 200 210 220 pF1KB6 LASTSKPVVKLLHNRSNNKYSYTSTSDDNLLKNIELFDKLALRFHGRLLFLKDVLGDEIC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LASTSKPVVKLLHNRSNNKYSYTSTSDDNLLKNIELFDKLALRFHGRLLFLKDVLGDEIC 190 200 210 220 230 240 230 240 250 260 270 280 pF1KB6 CWSFYGQGRKIAEVCCTSIVYATEKKQTKVEFPEARIFEETLNILIYETPRGPDPALLEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 CWSFYGQGRKIAEVCCTSIVYATEKKQTKVEFPEARIFEETLNILIYETPRGPDPALLEA 250 260 270 280 290 300 290 300 310 320 pF1KB6 TGGAAGAGGAGRGEDEENREHRVRRIHVRRHITHDERPHGQQIVFKD ::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TGGAAGAGGAGRGEDEENREHRVRRIHVRRHITHDERPHGQQIVFKD 310 320 330 340 >>XP_011544086 (OMIM: 608947) PREDICTED: BTB/POZ domain- (202 aa) initn: 1289 init1: 1289 opt: 1289 Z-score: 1392.7 bits: 265.3 E(85289): 7.8e-71 Smith-Waterman score: 1289; 98.5% identity (99.0% similar) in 196 aa overlap (134-329:7-202) 110 120 130 140 150 160 pF1KB6 SVPLPESTRELGELLGEARYYLVQGLIEDCQLALQQKRETLSPLCLIPMVTSPREEQQLL .: :::::::::::::::::::::::::: XP_011 MPMFLGELPKQQKRETLSPLCLIPMVTSPREEQQLL 10 20 30 170 180 190 200 210 220 pF1KB6 ASTSKPVVKLLHNRSNNKYSYTSTSDDNLLKNIELFDKLALRFHGRLLFLKDVLGDEICC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ASTSKPVVKLLHNRSNNKYSYTSTSDDNLLKNIELFDKLALRFHGRLLFLKDVLGDEICC 40 50 60 70 80 90 230 240 250 260 270 280 pF1KB6 WSFYGQGRKIAEVCCTSIVYATEKKQTKVEFPEARIFEETLNILIYETPRGPDPALLEAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 WSFYGQGRKIAEVCCTSIVYATEKKQTKVEFPEARIFEETLNILIYETPRGPDPALLEAT 100 110 120 130 140 150 290 300 310 320 pF1KB6 GGAAGAGGAGRGEDEENREHRVRRIHVRRHITHDERPHGQQIVFKD :::::::::::::::::::::::::::::::::::::::::::::: XP_011 GGAAGAGGAGRGEDEENREHRVRRIHVRRHITHDERPHGQQIVFKD 160 170 180 190 200 >>XP_016878593 (OMIM: 608947) PREDICTED: BTB/POZ domain- (178 aa) initn: 1190 init1: 1190 opt: 1190 Z-score: 1287.1 bits: 245.6 E(85289): 5.9e-65 Smith-Waterman score: 1190; 100.0% identity (100.0% similar) in 178 aa overlap (152-329:1-178) 130 140 150 160 170 180 pF1KB6 RYYLVQGLIEDCQLALQQKRETLSPLCLIPMVTSPREEQQLLASTSKPVVKLLHNRSNNK :::::::::::::::::::::::::::::: XP_016 MVTSPREEQQLLASTSKPVVKLLHNRSNNK 10 20 30 190 200 210 220 230 240 pF1KB6 YSYTSTSDDNLLKNIELFDKLALRFHGRLLFLKDVLGDEICCWSFYGQGRKIAEVCCTSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 YSYTSTSDDNLLKNIELFDKLALRFHGRLLFLKDVLGDEICCWSFYGQGRKIAEVCCTSI 40 50 60 70 80 90 250 260 270 280 290 300 pF1KB6 VYATEKKQTKVEFPEARIFEETLNILIYETPRGPDPALLEATGGAAGAGGAGRGEDEENR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VYATEKKQTKVEFPEARIFEETLNILIYETPRGPDPALLEATGGAAGAGGAGRGEDEENR 100 110 120 130 140 150 310 320 pF1KB6 EHRVRRIHVRRHITHDERPHGQQIVFKD :::::::::::::::::::::::::::: XP_016 EHRVRRIHVRRHITHDERPHGQQIVFKD 160 170 >>XP_016880482 (OMIM: 191161) PREDICTED: BTB/POZ domain- (391 aa) initn: 1111 init1: 1087 opt: 1095 Z-score: 1180.4 bits: 227.0 E(85289): 5.2e-59 Smith-Waterman score: 1100; 66.8% identity (86.2% similar) in 247 aa overlap (6-252:2-239) 10 20 30 40 50 60 pF1KB6 MSAEASGPAAAAAPSLEAPKPSGLEPGPAAYGLKPLTPNSKYVKLNVGGSLHYTTLRTLT :: . : :: ::.. : :: ..:::.:::::::.:::.:.:: XP_016 MSGDTCLCPASGAKPKLSGFKGG----GL-----GNKYVQLNVGGSLYYTTVRALT 10 20 30 40 70 80 90 100 110 120 pF1KB6 GQDTMLKAMFSGRVEVLTDAGGWVLIDRSGRHFGTILNYLRDGSVPLPESTRELGELLGE .:::::::::::.::::: ::.:::: :.::::::::::: .. ::.. .:. ::..: XP_016 RHDTMLKAMFSGRMEVLTDKEGWILIDRCGKHFGTILNYLRDDTITLPQNRQEIKELMAE 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB6 ARYYLVQGLIEDCQLALQQKRETLSPLCLIPMVTSPREEQQLLASTSKPVVKLLHNRSNN :.:::.:::.. :: :::.:... .:.: ::..:: .::..:. :..:::::::.::::: XP_016 AKYYLIQGLVNMCQSALQDKKDSYQPVCNIPIITSLKEEERLIESSTKPVVKLLYNRSNN 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB6 KYSYTSTSDDNLLKNIELFDKLALRFHGRLLFLKDVLGDEICCWSFYGQGRKIAEVCCTS ::::::.:::.:::::::::::.:::.::.::.:::.:::::::::::::::.::::::: XP_016 KYSYTSNSDDHLLKNIELFDKLSLRFNGRVLFIKDVIGDEICCWSFYGQGRKLAEVCCTS 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB6 IVYATEKKQTKVEFPEARIFEETLNILIYETPRGPDPALLEATGGAAGAGGAGRGEDEEN :::::::::::: XP_016 IVYATEKKQTKVWGIAPAWVGEDTHPLCGGRGRAVTSTEQKGHGLGSFFQTRWNSQRPES 230 240 250 260 270 280 >>XP_016878594 (OMIM: 608947) PREDICTED: BTB/POZ domain- (175 aa) initn: 906 init1: 906 opt: 906 Z-score: 982.2 bits: 189.1 E(85289): 5.7e-48 Smith-Waterman score: 906; 98.6% identity (100.0% similar) in 140 aa overlap (1-140:1-140) 10 20 30 40 50 60 pF1KB6 MSAEASGPAAAAAPSLEAPKPSGLEPGPAAYGLKPLTPNSKYVKLNVGGSLHYTTLRTLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSAEASGPAAAAAPSLEAPKPSGLEPGPAAYGLKPLTPNSKYVKLNVGGSLHYTTLRTLT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 GQDTMLKAMFSGRVEVLTDAGGWVLIDRSGRHFGTILNYLRDGSVPLPESTRELGELLGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GQDTMLKAMFSGRVEVLTDAGGWVLIDRSGRHFGTILNYLRDGSVPLPESTRELGELLGE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 ARYYLVQGLIEDCQLALQQKRETLSPLCLIPMVTSPREEQQLLASTSKPVVKLLHNRSNN ::::::::::::::::::.. XP_016 ARYYLVQGLIEDCQLALQSRAYSGFSSCSRNVFLQLVHQTRVQSRSSRCIWLSAS 130 140 150 160 170 >>XP_016878595 (OMIM: 608947) PREDICTED: BTB/POZ domain- (173 aa) initn: 903 init1: 903 opt: 903 Z-score: 979.0 bits: 188.5 E(85289): 8.6e-48 Smith-Waterman score: 904; 90.0% identity (90.6% similar) in 160 aa overlap (1-151:1-160) 10 20 30 40 50 60 pF1KB6 MSAEASGPAAAAAPSLEAPKPSGLEPGPAAYGLKPLTPNSKYVKLNVGGSLHYTTLRTLT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MSAEASGPAAAAAPSLEAPKPSGLEPGPAAYGLKPLTPNSKYVKLNVGGSLHYTTLRTLT 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 GQDTMLKAMFSGRVEVLTDAGGWVLIDRSGRHFGTILNYLRDGSVPLPESTRELGELLGE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GQDTMLKAMFSGRVEVLTDAGGWVLIDRSGRHFGTILNYLRDGSVPLPESTRELGELLGE 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 ARYYLVQGLIEDCQLALQ---------QKRETLSPLCLIPMVTSPREEQQLLASTSKPVV :::::::::::::::::: : :. :: : : XP_016 ARYYLVQGLIEDCQLALQSLSVAQAGVQWRDLGSPQPLPPRFKQFSCLSLPSS 130 140 150 160 170 180 190 200 210 220 230 pF1KB6 KLLHNRSNNKYSYTSTSDDNLLKNIELFDKLALRFHGRLLFLKDVLGDEICCWSFYGQGR 329 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 23:08:04 2016 done: Fri Nov 4 23:08:06 2016 Total Scan time: 7.540 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]