FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6488, 357 aa 1>>>pF1KB6488 357 - 357 aa - 357 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.4502+/-0.000831; mu= 18.7104+/- 0.051 mean_var=136.4848+/-24.943, 0's: 0 Z-trim(113.3): 64 B-trim: 46 in 1/51 Lambda= 0.109782 statistics sampled from 13894 (13960) to 13894 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.761), E-opt: 0.2 (0.429), width: 16 Scan time: 2.380 The best scores are: opt bits E(32554) CCDS6328.1 NOV gene_id:4856|Hs108|chr8 ( 357) 2606 423.7 1.2e-118 CCDS5151.1 CTGF gene_id:1490|Hs108|chr6 ( 349) 1357 225.9 4.1e-59 CCDS6371.1 WISP1 gene_id:8840|Hs108|chr8 ( 367) 1021 172.7 4.4e-43 CCDS5098.1 WISP3 gene_id:8838|Hs108|chr6 ( 354) 820 140.8 1.6e-33 CCDS5097.1 WISP3 gene_id:8838|Hs108|chr6 ( 372) 820 140.9 1.7e-33 CCDS13336.1 WISP2 gene_id:8839|Hs108|chr20 ( 250) 795 136.7 2.1e-32 CCDS706.1 CYR61 gene_id:3491|Hs108|chr1 ( 381) 578 102.6 5.9e-22 >>CCDS6328.1 NOV gene_id:4856|Hs108|chr8 (357 aa) initn: 2606 init1: 2606 opt: 2606 Z-score: 2243.8 bits: 423.7 E(32554): 1.2e-118 Smith-Waterman score: 2606; 99.7% identity (100.0% similar) in 357 aa overlap (1-357:1-357) 10 20 30 40 50 60 pF1KB6 MQSVQSTSFCLRKQCLCLTFLLLHLLGQVAATQRCPPQCPGQCPATPPTCAPGVRAVLDG :::::::::::::::::::::::::::::::::::::::::.:::::::::::::::::: CCDS63 MQSVQSTSFCLRKQCLCLTFLLLHLLGQVAATQRCPPQCPGRCPATPPTCAPGVRAVLDG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 CSCCLVCARQRGESCSDLEPCDESSGLYCDRSADPSNQTGICTAVEGDNCVFDGVIYRSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 CSCCLVCARQRGESCSDLEPCDESSGLYCDRSADPSNQTGICTAVEGDNCVFDGVIYRSG 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 EKFQPSCKFQCTCRDGQIGCVPRCQLDVLLPEPNCPAPRKVEVPGECCEKWICGPDEEDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 EKFQPSCKFQCTCRDGQIGCVPRCQLDVLLPEPNCPAPRKVEVPGECCEKWICGPDEEDS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 LGGLTLAAYRPEATLGVEVSDSSVNCIEQTTEWTACSKSCGMGFSTRVTNRNRQCEMLKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 LGGLTLAAYRPEATLGVEVSDSSVNCIEQTTEWTACSKSCGMGFSTRVTNRNRQCEMLKQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 TRLCMVRPCEQEPEQPTDKKGKKCLRTKKSLKAIHLQFKNCTSLHTYKPRFCGVCSDGRC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 TRLCMVRPCEQEPEQPTDKKGKKCLRTKKSLKAIHLQFKNCTSLHTYKPRFCGVCSDGRC 250 260 270 280 290 300 310 320 330 340 350 pF1KB6 CTPHNTKTIQAEFQCSPGQIVKKPVMVIGTCTCHTNCPKNNEAFLQELELKTTRGKM ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 CTPHNTKTIQAEFQCSPGQIVKKPVMVIGTCTCHTNCPKNNEAFLQELELKTTRGKM 310 320 330 340 350 >>CCDS5151.1 CTGF gene_id:1490|Hs108|chr6 (349 aa) initn: 1352 init1: 910 opt: 1357 Z-score: 1174.8 bits: 225.9 E(32554): 4.1e-59 Smith-Waterman score: 1357; 51.5% identity (74.6% similar) in 338 aa overlap (21-357:15-348) 10 20 30 40 50 pF1KB6 MQSVQSTSFCLRKQCLCLTFLLLHLLGQVAATQRCPPQCPGQCPATP-PTCAPGVRAVLD .:: : .. :. : : : .:: : : : :: ::: CCDS51 MTAASMGPVRVAFVVLLALCSRPAVGQNCSGPC--RCPDEPAPRCPAGVSLVLD 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 GCSCCLVCARQRGESCSDLEPCDESSGLYCDRSADPSNQTGICTAVEGDNCVFDGVIYRS ::.:: :::.: :: :.. .::: .::.: .. . . :.::: .: :.: :..::: CCDS51 GCGCCRVCAKQLGELCTERDPCDPHKGLFCHFGSPANRKIGVCTAKDGAPCIFGGTVYRS 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 GEKFQPSCKFQCTCRDGQIGCVPRCQLDVLLPEPNCPAPRKVEVPGECCEKWICGPDEED ::.:: :::.:::: :: .::.: :..:: :: :.:: ::.:..::.:::.:.: ... CCDS51 GESFQSSCKYQCTCLDGAVGCMPLCSMDVRLPSPDCPFPRRVKLPGKCCEEWVCDEPKDQ 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB6 SLGGLTLAAYRPEATLGVEVSDSSVNCIEQTTEWTACSKSCGMGFSTRVTNRNRQCEMLK .. : .::::: : :.: . . .::. :::::.::::.::::.:::::: : .:.. : CCDS51 TVVGPALAAYRLEDTFGPDPTMIRANCLVQTTEWSACSKTCGMGISTRVTNDNASCRLEK 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB6 QTRLCMVRPCEQEPEQPTDKKGKKCLRTKKSLKAIHLQFKNCTSLHTYKPRFCGVCSDGR :.::::::::: . :. ::::::.:: : : :......:::..::. .:::::.::: CCDS51 QSRLCMVRPCEADLEENI-KKGKKCIRTPKISKPIKFELSGCTSMKTYRAKFCGVCTDGR 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB6 CCTPHNTKTIQAEFQCSPGQIVKKPVMVIGTCTCHTNCPKNNEAFLQELELKTTRGKM ::::: : :. .::.: :...:: .: : ::.:: ::: .:. : . : . : : CCDS51 CCTPHRTTTLPVEFKCPDGEVMKKNMMFIKTCACHYNCPGDNDIF-ESLYYRKMYGDMA 300 310 320 330 340 >>CCDS6371.1 WISP1 gene_id:8840|Hs108|chr8 (367 aa) initn: 688 init1: 293 opt: 1021 Z-score: 887.0 bits: 172.7 E(32554): 4.4e-43 Smith-Waterman score: 1021; 43.1% identity (65.8% similar) in 313 aa overlap (37-344:46-353) 10 20 30 40 50 60 pF1KB6 TSFCLRKQCLCLTFLLLHLLGQVAATQRCPPQ-C--PGQCPATPPTCAPGVRAVLDGCSC :: : : .:: .:: : :: . ::: : CCDS63 AASTVLATALSPAPTTMDFTPAPLEDTSSRPQFCKWPCECPPSPPRCPLGVSLITDGCEC 20 30 40 50 60 70 70 80 90 100 110 120 pF1KB6 CLVCARQRGESCSDLEPCDESSGLYCDRSAD-PSNQTGICTAVEGDNCVFDGVIYRSGEK : .::.: :..:.. :: ::::: :.: : :.:. : : .::.::: : .:.. CCDS63 CKMCAQQLGDNCTEAAICDPHRGLYCDYSGDRPRYAIGVCAQVVGVGCVLDGVRYNNGQS 80 90 100 110 120 130 130 140 150 160 170 180 pF1KB6 FQPSCKFQCTCRDGQIGCVPRCQLDVLLPEPNCPAPRKVEVPGECCEKWICGPDEEDSLG :::.::..::: :: .::.: : : : :. :: ::.: .::.:::.:.: :.:. CCDS63 FQPNCKYNCTCIDGAVGCTPLC-LRVRPPRLWCPHPRRVSIPGHCCEQWVC---EDDAKR 140 150 160 170 180 190 190 200 210 220 230 240 pF1KB6 GLTLAAYRPEATLGV-EVSDSSVNCIEQTTEWTACSKSCGMGFSTRVTNRNRQCEMLKQT : : .: :: ::: :. :. :: :::.: :::..: : :: ... CCDS63 PRKTAPRDTGAFDAVGEVEAWHRNCIAYTSPWSPCSTSCGLGVSTRISNVNAQCWPEQES 200 210 220 230 240 250 250 260 270 280 290 300 pF1KB6 RLCMVRPCEQEPEQPTDKKGKKCLRTKKSLKAIHLQFKNCTSLHTYKPRFCGVCSDGRCC ::: .:::. . . : ::::: . . .... . .: : ..:.:..:::: :.::: CCDS63 RLCNLRPCDVDI-HTLIKAGKKCLAVYQPEASMNFTLAGCISTRSYQPKYCGVCMDNRCC 260 270 280 290 300 310 310 320 330 340 350 pF1KB6 TPHNTKTIQAEFQCSPGQIVKKPVMVIGTCTCHTNCPKNNEAFLQELELKTTRGKM :...:::.. ::: : .. :. :..: :. .: . :. : CCDS63 IPYKSKTIDVSFQCPDGLGFSRQVLWINACFCNLSCRNPNDIFADLESYPDFSEIAN 320 330 340 350 360 >>CCDS5098.1 WISP3 gene_id:8838|Hs108|chr6 (354 aa) initn: 870 init1: 254 opt: 820 Z-score: 715.1 bits: 140.8 E(32554): 1.6e-33 Smith-Waterman score: 821; 37.2% identity (62.8% similar) in 336 aa overlap (27-350:36-353) 10 20 30 40 50 pF1KB6 MQSVQSTSFCLRKQCLCLTFLLLHLLGQVA-ATQR---CPPQCPGQCPATPPTCAP :.:. : :: : : .:: : : : CCDS50 FSTLLLAGLAQFCCRVQGTGPLDTTPEGRPGEVSDAPQRKQFCHWPC--KCPQQKPRCPP 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 GVRAVLDGCSCCLVCARQRGESCSDLEPCDESSGLYCDRSAD-PSNQTGICTAVEGDNCV :: : :::.:: .::.: :: :.. . :: .::::: :.: : .::.:. . . .: CCDS50 GVSLVRDGCGCCKICAKQPGEICNEADLCDPHKGLYCDYSVDRPRYETGVCAYLVAVGCE 70 80 90 100 110 120 120 130 140 150 160 pF1KB6 FDGVIYRSGEKFQPSCKFQCTCRDGQIGCVPRCQLDVLLPE---PNCPAPRKVEVPGECC :. : :..:. :::. :.: : .: :::.: ...:. .: . . :. CCDS50 FNQVHYHNGQVFQPNPLFSCLCVSGAIGCTP-----LFIPKLAGSHCSGAKG----GKKS 130 140 150 160 170 170 180 190 200 210 220 pF1KB6 EKWICGPD---EEDSLGGLTLAAYRPEATLGVEVSDSSVNCIEQTTEWTACSKSCGMGFS .. :. . .. : . :. ::: . . .:. :.:.:: ::..::::.: CCDS50 DQSNCSLEPLLQQLSTSYKTMPAYRNLPLIWKK------KCLVQATKWTPCSRTCGMGIS 180 190 200 210 220 230 240 250 260 270 280 pF1KB6 TRVTNRNRQCEMLKQTRLCMVRPCEQEPEQPTD-KKGKKCLRTKKSLKAIHLQFKNCTSL .::::.: .::: :. :::...::... . ::: : : . :: .. :..:.: CCDS50 NRVTNENSNCEMRKEKRLCYIQPCDSNILKTIKIPKGKTCQPTFQLSKAEKFVFSGCSST 230 240 250 260 270 280 290 300 310 320 330 340 pF1KB6 HTYKPRFCGVCSDGRCCTPHNTKTIQAEFQCSPGQIVKKPVMVIGTCTCHTNCPKNNEAF ..::: :::.: : ::: :...: : .:.: : .. : .:.:. :: . .. : CCDS50 QSYKPTFCGICLDKRCCIPNKSKMITIQFDCPNEGSFKWKMLWITSCVCQRNCREPGDIF 290 300 310 320 330 340 350 pF1KB6 LQELELKTTRGKM .::.. CCDS50 -SELKIL 350 >>CCDS5097.1 WISP3 gene_id:8838|Hs108|chr6 (372 aa) initn: 870 init1: 254 opt: 820 Z-score: 714.9 bits: 140.9 E(32554): 1.7e-33 Smith-Waterman score: 821; 37.2% identity (62.8% similar) in 336 aa overlap (27-350:54-371) 10 20 30 40 50 pF1KB6 MQSVQSTSFCLRKQCLCLTFLLLHLLGQVA-ATQR---CPPQCPGQCPATPPTCAP :.:. : :: : : .:: : : : CCDS50 FSTLLLAGLAQFCCRVQGTGPLDTTPEGRPGEVSDAPQRKQFCHWPC--KCPQQKPRCPP 30 40 50 60 70 80 60 70 80 90 100 110 pF1KB6 GVRAVLDGCSCCLVCARQRGESCSDLEPCDESSGLYCDRSAD-PSNQTGICTAVEGDNCV :: : :::.:: .::.: :: :.. . :: .::::: :.: : .::.:. . . .: CCDS50 GVSLVRDGCGCCKICAKQPGEICNEADLCDPHKGLYCDYSVDRPRYETGVCAYLVAVGCE 90 100 110 120 130 140 120 130 140 150 160 pF1KB6 FDGVIYRSGEKFQPSCKFQCTCRDGQIGCVPRCQLDVLLPE---PNCPAPRKVEVPGECC :. : :..:. :::. :.: : .: :::.: ...:. .: . . :. CCDS50 FNQVHYHNGQVFQPNPLFSCLCVSGAIGCTP-----LFIPKLAGSHCSGAKG----GKKS 150 160 170 180 190 170 180 190 200 210 220 pF1KB6 EKWICGPD---EEDSLGGLTLAAYRPEATLGVEVSDSSVNCIEQTTEWTACSKSCGMGFS .. :. . .. : . :. ::: . . .:. :.:.:: ::..::::.: CCDS50 DQSNCSLEPLLQQLSTSYKTMPAYRNLPLIWKK------KCLVQATKWTPCSRTCGMGIS 200 210 220 230 240 230 240 250 260 270 280 pF1KB6 TRVTNRNRQCEMLKQTRLCMVRPCEQEPEQPTD-KKGKKCLRTKKSLKAIHLQFKNCTSL .::::.: .::: :. :::...::... . ::: : : . :: .. :..:.: CCDS50 NRVTNENSNCEMRKEKRLCYIQPCDSNILKTIKIPKGKTCQPTFQLSKAEKFVFSGCSST 250 260 270 280 290 300 290 300 310 320 330 340 pF1KB6 HTYKPRFCGVCSDGRCCTPHNTKTIQAEFQCSPGQIVKKPVMVIGTCTCHTNCPKNNEAF ..::: :::.: : ::: :...: : .:.: : .. : .:.:. :: . .. : CCDS50 QSYKPTFCGICLDKRCCIPNKSKMITIQFDCPNEGSFKWKMLWITSCVCQRNCREPGDIF 310 320 330 340 350 360 350 pF1KB6 LQELELKTTRGKM .::.. CCDS50 -SELKIL 370 >>CCDS13336.1 WISP2 gene_id:8839|Hs108|chr20 (250 aa) initn: 549 init1: 309 opt: 795 Z-score: 695.3 bits: 136.7 E(32554): 2.1e-32 Smith-Waterman score: 795; 47.2% identity (67.0% similar) in 233 aa overlap (18-249:10-237) 10 20 30 40 50 60 pF1KB6 MQSVQSTSFCLRKQCLCLTFLLLHLLGQVAATQRCPPQCPGQCPATPPTCAPGVRAVLDG :.: :: ::..: :: :: : :: :: : :: :::: CCDS13 MRGTPKTHLLAFSLLCLLSKVR-TQLCPTPCT--CPWPPPRCPLGVPLVLDG 10 20 30 40 70 80 90 100 110 pF1KB6 CSCCLVCARQRGESCSDLEPCDESSGLYCDRSADPSNQTGICTAVEGDN-CVFDGVIYRS :.:: ::::. :: :..:. :: :.:: :. .: :... ..: .: :. : .: .:: CCDS13 CGCCRVCARRLGEPCDQLHVCDASQGLVCQPGAGPGGRGALCLLAEDDSSCEVNGRLYRE 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB6 GEKFQPSCKFQCTCRDGQIGCVPRCQLDVLLPEPNCPAPRKVEVPGECCEKWICGPDEED :: ::: :...: :.:: . ::: :. :: :: .:: ::.::: :.:: .:.:: . CCDS13 GETFQPHCSIRCRCEDGGFTCVPLCSEDVRLPSWDCPHPRRVEVLGKCCPEWVCG--QGG 110 120 130 140 150 160 180 190 200 210 220 230 pF1KB6 SLGGLTLAAYRPEATLGVEVSDSSVNCIEQTTEWTACSKSCGMGFSTRVTNRNRQCEMLK .:: : : :. . : .: : : .: : :: .::.:..:::.:.:: :.. CCDS13 GLGTQPLPAQGPQFSGLVSSLPPGVPCPEWSTAWGPCSTTCGLGMATRVSNQNRFCRLET 170 180 190 200 210 220 240 250 260 270 280 290 pF1KB6 QTRLCMVRPCEQEPEQPTDKKGKKCLRTKKSLKAIHLQFKNCTSLHTYKPRFCGVCSDGR : :::. ::: CCDS13 QRRLCLSRPCPPSRGRSPQNSAF 230 240 250 >>CCDS706.1 CYR61 gene_id:3491|Hs108|chr1 (381 aa) initn: 1155 init1: 345 opt: 578 Z-score: 507.6 bits: 102.6 E(32554): 5.9e-22 Smith-Waterman score: 1113; 44.2% identity (65.5% similar) in 362 aa overlap (16-343:9-365) 10 20 30 40 50 60 pF1KB6 MQSVQSTSFCLRKQCLCLTFLLLHLLGQVAATQRCPPQCPGQCPATPPTCAPGVRAVLDG : :. :::: . .: :: : .:: : ::::: : :: CCDS70 MSSRIARALALVVTLLHLTRLALST--CPAAC--HCPLEAPKCAPGVGLVRDG 10 20 30 40 70 80 90 100 110 pF1KB6 CSCCLVCARQRGESCSDLEPCDESSGLYCDRSADPSNQTGICTA-VEGDNCVFDGVIYRS :.:: :::.: .:.:: .:::...:: :. .:. . ::: : :: : ... ::.. CCDS70 CGCCKVCAKQLNEDCSKTQPCDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQN 50 60 70 80 90 100 120 130 140 150 160 170 pF1KB6 GEKFQPSCKFQCTCRDGQIGCVPRCQLDVLLPEPNCPAPRKVEVPGECCEKWICGPD--- ::.:::.:: :::: :: .::.: : .. ::. .:: :: :.: :.:::.:.: : CCDS70 GESFQPNCKHQCTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSIK 110 120 130 140 150 160 180 190 200 pF1KB6 ----EEDSLGG--LTLAAYRPEATLGVEV----SDSSVN--------------------C ..:.: : : . : . : : . :. . ::.. : CCDS70 DPMEDQDGLLGKELGFDASEVELTRNNELIAVGKGSSLKRLPVFGMEPRILYNPLQGQKC 170 180 190 200 210 220 210 220 230 240 250 260 pF1KB6 IEQTTEWTACSKSCGMGFSTRVTNRNRQCEMLKQTRLCMVRPCEQEPEQPTDKKGKKCLR : ::: :. :::.:: :.:::::: : .:...:.::.: :::: : : . :::::: . CCDS70 IVQTTSWSQCSKTCGTGISTRVTNDNPECRLVKETRICEVRPCGQ-PVYSSLKKGKKCSK 230 240 250 260 270 280 270 280 290 300 310 320 pF1KB6 TKKSLKAIHLQFKNCTSLHTYKPRFCGVCSDGRCCTPHNTKTIQAEFQCSPGQIVKKPVM :::: . ... . .: :.. :.:..:: : :::::::. :.:.. .:.: :. .: :: CCDS70 TKKSPEPVRFTYAGCLSVKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVM 290 300 310 320 330 340 330 340 350 pF1KB6 VIGTCTCHTNCPKNNEAFLQELELKTTRGKM .: .: :. :::. ::: CCDS70 MIQSCKCNYNCPHANEAAFPFYRLFNDIHKFRD 350 360 370 380 357 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 23:08:33 2016 done: Fri Nov 4 23:08:33 2016 Total Scan time: 2.380 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]