Result of FASTA (omim) for
pF1KB6488
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6488, 357 aa
1>>>pF1KB6488 357 - 357 aa - 357 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 6.3234+/-0.000349; mu= 13.3835+/- 0.022
mean_var=146.6994+/-28.014, 0's: 0 Z-trim(120.3): 99 B-trim: 0 in 0/53
Lambda= 0.105891
statistics sampled from 35204 (35373) to 35204 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.749), E-opt: 0.2 (0.415), width: 16
Scan time: 8.500
The best scores are: opt bits E(85289)
NP_002505 (OMIM: 164958) protein NOV homolog precu ( 357) 2606 409.5 6e-114
NP_001892 (OMIM: 121009) connective tissue growth ( 349) 1366 220.0 6.3e-57
NP_003873 (OMIM: 603398) WNT1-inducible-signaling ( 367) 1021 167.3 4.8e-41
XP_011534522 (OMIM: 208230,603400) PREDICTED: WNT1 ( 354) 820 136.6 8.1e-32
NP_003871 (OMIM: 208230,603400) WNT1-inducible-sig ( 354) 820 136.6 8.1e-32
NP_937882 (OMIM: 208230,603400) WNT1-inducible-sig ( 372) 820 136.6 8.4e-32
NP_003872 (OMIM: 603399) WNT1-inducible-signaling ( 250) 795 132.6 9.1e-31
NP_001310299 (OMIM: 603399) WNT1-inducible-signali ( 250) 795 132.6 9.1e-31
NP_001545 (OMIM: 602369) protein CYR61 precursor [ ( 381) 578 99.7 1.1e-20
XP_011534525 (OMIM: 208230,603400) PREDICTED: WNT1 ( 160) 459 81.1 1.9e-15
NP_543028 (OMIM: 603398) WNT1-inducible-signaling ( 280) 302 57.4 4.6e-08
XP_016883606 (OMIM: 603399) PREDICTED: WNT1-induci ( 162) 295 56.0 6.7e-08
NP_001310298 (OMIM: 603399) WNT1-inducible-signali ( 218) 295 56.2 8.2e-08
XP_011534524 (OMIM: 208230,603400) PREDICTED: WNT1 ( 158) 292 55.6 9.1e-08
NP_001191799 (OMIM: 603398) WNT1-inducible-signali ( 122) 274 52.7 5.1e-07
NP_001191798 (OMIM: 603398) WNT1-inducible-signali ( 155) 268 51.9 1.1e-06
NP_008967 (OMIM: 601521) endothelial cell-specific ( 184) 199 41.4 0.0019
NP_001159605 (OMIM: 219000,607830) extracellular m (1976) 213 44.7 0.0021
NP_001129076 (OMIM: 601521) endothelial cell-speci ( 134) 194 40.5 0.0026
XP_006714379 (OMIM: 219000,607830) PREDICTED: extr (3936) 213 45.0 0.0034
NP_079350 (OMIM: 219000,607830) extracellular matr (4012) 213 45.0 0.0034
XP_011542734 (OMIM: 610700) PREDICTED: serine prot ( 343) 194 41.0 0.0049
XP_011542733 (OMIM: 610700) PREDICTED: serine prot ( 380) 194 41.0 0.0052
XP_016870188 (OMIM: 610413) PREDICTED: insulin-lik ( 174) 188 39.7 0.0059
NP_710159 (OMIM: 610700) serine protease HTRA4 pre ( 476) 194 41.1 0.0061
NP_955381 (OMIM: 609344) kielin/chordin-like prote ( 814) 197 41.8 0.0063
XP_016867683 (OMIM: 609344) PREDICTED: kielin/chor (1093) 197 42.0 0.0077
XP_016867682 (OMIM: 609344) PREDICTED: kielin/chor (1102) 197 42.0 0.0078
NP_001007564 (OMIM: 610413) insulin-like growth fa ( 278) 188 39.9 0.008
>>NP_002505 (OMIM: 164958) protein NOV homolog precursor (357 aa)
initn: 2606 init1: 2606 opt: 2606 Z-score: 2166.7 bits: 409.5 E(85289): 6e-114
Smith-Waterman score: 2606; 99.7% identity (100.0% similar) in 357 aa overlap (1-357:1-357)
10 20 30 40 50 60
pF1KB6 MQSVQSTSFCLRKQCLCLTFLLLHLLGQVAATQRCPPQCPGQCPATPPTCAPGVRAVLDG
:::::::::::::::::::::::::::::::::::::::::.::::::::::::::::::
NP_002 MQSVQSTSFCLRKQCLCLTFLLLHLLGQVAATQRCPPQCPGRCPATPPTCAPGVRAVLDG
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 CSCCLVCARQRGESCSDLEPCDESSGLYCDRSADPSNQTGICTAVEGDNCVFDGVIYRSG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 CSCCLVCARQRGESCSDLEPCDESSGLYCDRSADPSNQTGICTAVEGDNCVFDGVIYRSG
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 EKFQPSCKFQCTCRDGQIGCVPRCQLDVLLPEPNCPAPRKVEVPGECCEKWICGPDEEDS
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 EKFQPSCKFQCTCRDGQIGCVPRCQLDVLLPEPNCPAPRKVEVPGECCEKWICGPDEEDS
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 LGGLTLAAYRPEATLGVEVSDSSVNCIEQTTEWTACSKSCGMGFSTRVTNRNRQCEMLKQ
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LGGLTLAAYRPEATLGVEVSDSSVNCIEQTTEWTACSKSCGMGFSTRVTNRNRQCEMLKQ
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 TRLCMVRPCEQEPEQPTDKKGKKCLRTKKSLKAIHLQFKNCTSLHTYKPRFCGVCSDGRC
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TRLCMVRPCEQEPEQPTDKKGKKCLRTKKSLKAIHLQFKNCTSLHTYKPRFCGVCSDGRC
250 260 270 280 290 300
310 320 330 340 350
pF1KB6 CTPHNTKTIQAEFQCSPGQIVKKPVMVIGTCTCHTNCPKNNEAFLQELELKTTRGKM
:::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 CTPHNTKTIQAEFQCSPGQIVKKPVMVIGTCTCHTNCPKNNEAFLQELELKTTRGKM
310 320 330 340 350
>>NP_001892 (OMIM: 121009) connective tissue growth fact (349 aa)
initn: 1361 init1: 919 opt: 1366 Z-score: 1143.1 bits: 220.0 E(85289): 6.3e-57
Smith-Waterman score: 1366; 51.8% identity (74.9% similar) in 338 aa overlap (21-357:15-348)
10 20 30 40 50
pF1KB6 MQSVQSTSFCLRKQCLCLTFLLLHLLGQVAATQRCPPQCPGQCPATP-PTCAPGVRAVLD
.:: : .. :. : : : .:: : : : :: :::
NP_001 MTAASMGPVRVAFVVLLALCSRPAVGQNCSGPC--RCPDEPAPRCPAGVSLVLD
10 20 30 40 50
60 70 80 90 100 110
pF1KB6 GCSCCLVCARQRGESCSDLEPCDESSGLYCDRSADPSNQTGICTAVEGDNCVFDGVIYRS
::.:: :::.: :: :.. .::: .::.:: .. . . :.::: .: :.: :..:::
NP_001 GCGCCRVCAKQLGELCTERDPCDPHKGLFCDFGSPANRKIGVCTAKDGAPCIFGGTVYRS
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 GEKFQPSCKFQCTCRDGQIGCVPRCQLDVLLPEPNCPAPRKVEVPGECCEKWICGPDEED
::.:: :::.:::: :: .::.: :..:: :: :.:: ::.:..::.:::.:.: ...
NP_001 GESFQSSCKYQCTCLDGAVGCMPLCSMDVRLPSPDCPFPRRVKLPGKCCEEWVCDEPKDQ
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB6 SLGGLTLAAYRPEATLGVEVSDSSVNCIEQTTEWTACSKSCGMGFSTRVTNRNRQCEMLK
.. : .::::: : :.: . . .::. :::::.::::.::::.:::::: : .:.. :
NP_001 TVVGPALAAYRLEDTFGPDPTMIRANCLVQTTEWSACSKTCGMGISTRVTNDNASCRLEK
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB6 QTRLCMVRPCEQEPEQPTDKKGKKCLRTKKSLKAIHLQFKNCTSLHTYKPRFCGVCSDGR
:.::::::::: . :. ::::::.:: : : :......:::..::. .:::::.:::
NP_001 QSRLCMVRPCEADLEENI-KKGKKCIRTPKISKPIKFELSGCTSMKTYRAKFCGVCTDGR
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB6 CCTPHNTKTIQAEFQCSPGQIVKKPVMVIGTCTCHTNCPKNNEAFLQELELKTTRGKM
::::: : :. .::.: :...:: .: : ::.:: ::: .:. : . : . : :
NP_001 CCTPHRTTTLPVEFKCPDGEVMKKNMMFIKTCACHYNCPGDNDIF-ESLYYRKMYGDMA
300 310 320 330 340
>>NP_003873 (OMIM: 603398) WNT1-inducible-signaling path (367 aa)
initn: 688 init1: 293 opt: 1021 Z-score: 858.0 bits: 167.3 E(85289): 4.8e-41
Smith-Waterman score: 1021; 43.1% identity (65.8% similar) in 313 aa overlap (37-344:46-353)
10 20 30 40 50 60
pF1KB6 TSFCLRKQCLCLTFLLLHLLGQVAATQRCPPQ-C--PGQCPATPPTCAPGVRAVLDGCSC
:: : : .:: .:: : :: . ::: :
NP_003 AASTVLATALSPAPTTMDFTPAPLEDTSSRPQFCKWPCECPPSPPRCPLGVSLITDGCEC
20 30 40 50 60 70
70 80 90 100 110 120
pF1KB6 CLVCARQRGESCSDLEPCDESSGLYCDRSAD-PSNQTGICTAVEGDNCVFDGVIYRSGEK
: .::.: :..:.. :: ::::: :.: : :.:. : : .::.::: : .:..
NP_003 CKMCAQQLGDNCTEAAICDPHRGLYCDYSGDRPRYAIGVCAQVVGVGCVLDGVRYNNGQS
80 90 100 110 120 130
130 140 150 160 170 180
pF1KB6 FQPSCKFQCTCRDGQIGCVPRCQLDVLLPEPNCPAPRKVEVPGECCEKWICGPDEEDSLG
:::.::..::: :: .::.: : : : :. :: ::.: .::.:::.:.: :.:.
NP_003 FQPNCKYNCTCIDGAVGCTPLC-LRVRPPRLWCPHPRRVSIPGHCCEQWVC---EDDAKR
140 150 160 170 180 190
190 200 210 220 230 240
pF1KB6 GLTLAAYRPEATLGV-EVSDSSVNCIEQTTEWTACSKSCGMGFSTRVTNRNRQCEMLKQT
: : .: :: ::: :. :. :: :::.: :::..: : :: ...
NP_003 PRKTAPRDTGAFDAVGEVEAWHRNCIAYTSPWSPCSTSCGLGVSTRISNVNAQCWPEQES
200 210 220 230 240 250
250 260 270 280 290 300
pF1KB6 RLCMVRPCEQEPEQPTDKKGKKCLRTKKSLKAIHLQFKNCTSLHTYKPRFCGVCSDGRCC
::: .:::. . . : ::::: . . .... . .: : ..:.:..:::: :.:::
NP_003 RLCNLRPCDVDI-HTLIKAGKKCLAVYQPEASMNFTLAGCISTRSYQPKYCGVCMDNRCC
260 270 280 290 300 310
310 320 330 340 350
pF1KB6 TPHNTKTIQAEFQCSPGQIVKKPVMVIGTCTCHTNCPKNNEAFLQELELKTTRGKM
:...:::.. ::: : .. :. :..: :. .: . :. :
NP_003 IPYKSKTIDVSFQCPDGLGFSRQVLWINACFCNLSCRNPNDIFADLESYPDFSEIAN
320 330 340 350 360
>>XP_011534522 (OMIM: 208230,603400) PREDICTED: WNT1-ind (354 aa)
initn: 870 init1: 254 opt: 820 Z-score: 692.2 bits: 136.6 E(85289): 8.1e-32
Smith-Waterman score: 821; 37.2% identity (62.8% similar) in 336 aa overlap (27-350:36-353)
10 20 30 40 50
pF1KB6 MQSVQSTSFCLRKQCLCLTFLLLHLLGQVA-ATQR---CPPQCPGQCPATPPTCAP
:.:. : :: : : .:: : : :
XP_011 FSTLLLAGLAQFCCRVQGTGPLDTTPEGRPGEVSDAPQRKQFCHWPC--KCPQQKPRCPP
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB6 GVRAVLDGCSCCLVCARQRGESCSDLEPCDESSGLYCDRSAD-PSNQTGICTAVEGDNCV
:: : :::.:: .::.: :: :.. . :: .::::: :.: : .::.:. . . .:
XP_011 GVSLVRDGCGCCKICAKQPGEICNEADLCDPHKGLYCDYSVDRPRYETGVCAYLVAVGCE
70 80 90 100 110 120
120 130 140 150 160
pF1KB6 FDGVIYRSGEKFQPSCKFQCTCRDGQIGCVPRCQLDVLLPE---PNCPAPRKVEVPGECC
:. : :..:. :::. :.: : .: :::.: ...:. .: . . :.
XP_011 FNQVHYHNGQVFQPNPLFSCLCVSGAIGCTP-----LFIPKLAGSHCSGAKG----GKKS
130 140 150 160 170
170 180 190 200 210 220
pF1KB6 EKWICGPD---EEDSLGGLTLAAYRPEATLGVEVSDSSVNCIEQTTEWTACSKSCGMGFS
.. :. . .. : . :. ::: . . .:. :.:.:: ::..::::.:
XP_011 DQSNCSLEPLLQQLSTSYKTMPAYRNLPLIWKK------KCLVQATKWTPCSRTCGMGIS
180 190 200 210 220
230 240 250 260 270 280
pF1KB6 TRVTNRNRQCEMLKQTRLCMVRPCEQEPEQPTD-KKGKKCLRTKKSLKAIHLQFKNCTSL
.::::.: .::: :. :::...::... . ::: : : . :: .. :..:.:
XP_011 NRVTNENSNCEMRKEKRLCYIQPCDSNILKTIKIPKGKTCQPTFQLSKAEKFVFSGCSST
230 240 250 260 270 280
290 300 310 320 330 340
pF1KB6 HTYKPRFCGVCSDGRCCTPHNTKTIQAEFQCSPGQIVKKPVMVIGTCTCHTNCPKNNEAF
..::: :::.: : ::: :...: : .:.: : .. : .:.:. :: . .. :
XP_011 QSYKPTFCGICLDKRCCIPNKSKMITIQFDCPNEGSFKWKMLWITSCVCQRNCREPGDIF
290 300 310 320 330 340
350
pF1KB6 LQELELKTTRGKM
.::..
XP_011 -SELKIL
350
>>NP_003871 (OMIM: 208230,603400) WNT1-inducible-signali (354 aa)
initn: 870 init1: 254 opt: 820 Z-score: 692.2 bits: 136.6 E(85289): 8.1e-32
Smith-Waterman score: 821; 37.2% identity (62.8% similar) in 336 aa overlap (27-350:36-353)
10 20 30 40 50
pF1KB6 MQSVQSTSFCLRKQCLCLTFLLLHLLGQVA-ATQR---CPPQCPGQCPATPPTCAP
:.:. : :: : : .:: : : :
NP_003 FSTLLLAGLAQFCCRVQGTGPLDTTPEGRPGEVSDAPQRKQFCHWPC--KCPQQKPRCPP
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB6 GVRAVLDGCSCCLVCARQRGESCSDLEPCDESSGLYCDRSAD-PSNQTGICTAVEGDNCV
:: : :::.:: .::.: :: :.. . :: .::::: :.: : .::.:. . . .:
NP_003 GVSLVRDGCGCCKICAKQPGEICNEADLCDPHKGLYCDYSVDRPRYETGVCAYLVAVGCE
70 80 90 100 110 120
120 130 140 150 160
pF1KB6 FDGVIYRSGEKFQPSCKFQCTCRDGQIGCVPRCQLDVLLPE---PNCPAPRKVEVPGECC
:. : :..:. :::. :.: : .: :::.: ...:. .: . . :.
NP_003 FNQVHYHNGQVFQPNPLFSCLCVSGAIGCTP-----LFIPKLAGSHCSGAKG----GKKS
130 140 150 160 170
170 180 190 200 210 220
pF1KB6 EKWICGPD---EEDSLGGLTLAAYRPEATLGVEVSDSSVNCIEQTTEWTACSKSCGMGFS
.. :. . .. : . :. ::: . . .:. :.:.:: ::..::::.:
NP_003 DQSNCSLEPLLQQLSTSYKTMPAYRNLPLIWKK------KCLVQATKWTPCSRTCGMGIS
180 190 200 210 220
230 240 250 260 270 280
pF1KB6 TRVTNRNRQCEMLKQTRLCMVRPCEQEPEQPTD-KKGKKCLRTKKSLKAIHLQFKNCTSL
.::::.: .::: :. :::...::... . ::: : : . :: .. :..:.:
NP_003 NRVTNENSNCEMRKEKRLCYIQPCDSNILKTIKIPKGKTCQPTFQLSKAEKFVFSGCSST
230 240 250 260 270 280
290 300 310 320 330 340
pF1KB6 HTYKPRFCGVCSDGRCCTPHNTKTIQAEFQCSPGQIVKKPVMVIGTCTCHTNCPKNNEAF
..::: :::.: : ::: :...: : .:.: : .. : .:.:. :: . .. :
NP_003 QSYKPTFCGICLDKRCCIPNKSKMITIQFDCPNEGSFKWKMLWITSCVCQRNCREPGDIF
290 300 310 320 330 340
350
pF1KB6 LQELELKTTRGKM
.::..
NP_003 -SELKIL
350
>>NP_937882 (OMIM: 208230,603400) WNT1-inducible-signali (372 aa)
initn: 870 init1: 254 opt: 820 Z-score: 691.9 bits: 136.6 E(85289): 8.4e-32
Smith-Waterman score: 821; 37.2% identity (62.8% similar) in 336 aa overlap (27-350:54-371)
10 20 30 40 50
pF1KB6 MQSVQSTSFCLRKQCLCLTFLLLHLLGQVA-ATQR---CPPQCPGQCPATPPTCAP
:.:. : :: : : .:: : : :
NP_937 FSTLLLAGLAQFCCRVQGTGPLDTTPEGRPGEVSDAPQRKQFCHWPC--KCPQQKPRCPP
30 40 50 60 70 80
60 70 80 90 100 110
pF1KB6 GVRAVLDGCSCCLVCARQRGESCSDLEPCDESSGLYCDRSAD-PSNQTGICTAVEGDNCV
:: : :::.:: .::.: :: :.. . :: .::::: :.: : .::.:. . . .:
NP_937 GVSLVRDGCGCCKICAKQPGEICNEADLCDPHKGLYCDYSVDRPRYETGVCAYLVAVGCE
90 100 110 120 130 140
120 130 140 150 160
pF1KB6 FDGVIYRSGEKFQPSCKFQCTCRDGQIGCVPRCQLDVLLPE---PNCPAPRKVEVPGECC
:. : :..:. :::. :.: : .: :::.: ...:. .: . . :.
NP_937 FNQVHYHNGQVFQPNPLFSCLCVSGAIGCTP-----LFIPKLAGSHCSGAKG----GKKS
150 160 170 180 190
170 180 190 200 210 220
pF1KB6 EKWICGPD---EEDSLGGLTLAAYRPEATLGVEVSDSSVNCIEQTTEWTACSKSCGMGFS
.. :. . .. : . :. ::: . . .:. :.:.:: ::..::::.:
NP_937 DQSNCSLEPLLQQLSTSYKTMPAYRNLPLIWKK------KCLVQATKWTPCSRTCGMGIS
200 210 220 230 240
230 240 250 260 270 280
pF1KB6 TRVTNRNRQCEMLKQTRLCMVRPCEQEPEQPTD-KKGKKCLRTKKSLKAIHLQFKNCTSL
.::::.: .::: :. :::...::... . ::: : : . :: .. :..:.:
NP_937 NRVTNENSNCEMRKEKRLCYIQPCDSNILKTIKIPKGKTCQPTFQLSKAEKFVFSGCSST
250 260 270 280 290 300
290 300 310 320 330 340
pF1KB6 HTYKPRFCGVCSDGRCCTPHNTKTIQAEFQCSPGQIVKKPVMVIGTCTCHTNCPKNNEAF
..::: :::.: : ::: :...: : .:.: : .. : .:.:. :: . .. :
NP_937 QSYKPTFCGICLDKRCCIPNKSKMITIQFDCPNEGSFKWKMLWITSCVCQRNCREPGDIF
310 320 330 340 350 360
350
pF1KB6 LQELELKTTRGKM
.::..
NP_937 -SELKIL
370
>>NP_003872 (OMIM: 603399) WNT1-inducible-signaling path (250 aa)
initn: 549 init1: 309 opt: 795 Z-score: 673.4 bits: 132.6 E(85289): 9.1e-31
Smith-Waterman score: 795; 47.2% identity (67.0% similar) in 233 aa overlap (18-249:10-237)
10 20 30 40 50 60
pF1KB6 MQSVQSTSFCLRKQCLCLTFLLLHLLGQVAATQRCPPQCPGQCPATPPTCAPGVRAVLDG
:.: :: ::..: :: :: : :: :: : :: ::::
NP_003 MRGTPKTHLLAFSLLCLLSKVR-TQLCPTPCT--CPWPPPRCPLGVPLVLDG
10 20 30 40
70 80 90 100 110
pF1KB6 CSCCLVCARQRGESCSDLEPCDESSGLYCDRSADPSNQTGICTAVEGDN-CVFDGVIYRS
:.:: ::::. :: :..:. :: :.:: :. .: :... ..: .: :. : .: .::
NP_003 CGCCRVCARRLGEPCDQLHVCDASQGLVCQPGAGPGGRGALCLLAEDDSSCEVNGRLYRE
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB6 GEKFQPSCKFQCTCRDGQIGCVPRCQLDVLLPEPNCPAPRKVEVPGECCEKWICGPDEED
:: ::: :...: :.:: . ::: :. :: :: .:: ::.::: :.:: .:.:: .
NP_003 GETFQPHCSIRCRCEDGGFTCVPLCSEDVRLPSWDCPHPRRVEVLGKCCPEWVCG--QGG
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB6 SLGGLTLAAYRPEATLGVEVSDSSVNCIEQTTEWTACSKSCGMGFSTRVTNRNRQCEMLK
.:: : : :. . : .: : : .: : :: .::.:..:::.:.:: :..
NP_003 GLGTQPLPAQGPQFSGLVSSLPPGVPCPEWSTAWGPCSTTCGLGMATRVSNQNRFCRLET
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB6 QTRLCMVRPCEQEPEQPTDKKGKKCLRTKKSLKAIHLQFKNCTSLHTYKPRFCGVCSDGR
: :::. :::
NP_003 QRRLCLSRPCPPSRGRSPQNSAF
230 240 250
>>NP_001310299 (OMIM: 603399) WNT1-inducible-signaling p (250 aa)
initn: 549 init1: 309 opt: 795 Z-score: 673.4 bits: 132.6 E(85289): 9.1e-31
Smith-Waterman score: 795; 47.2% identity (67.0% similar) in 233 aa overlap (18-249:10-237)
10 20 30 40 50 60
pF1KB6 MQSVQSTSFCLRKQCLCLTFLLLHLLGQVAATQRCPPQCPGQCPATPPTCAPGVRAVLDG
:.: :: ::..: :: :: : :: :: : :: ::::
NP_001 MRGTPKTHLLAFSLLCLLSKVR-TQLCPTPCT--CPWPPPRCPLGVPLVLDG
10 20 30 40
70 80 90 100 110
pF1KB6 CSCCLVCARQRGESCSDLEPCDESSGLYCDRSADPSNQTGICTAVEGDN-CVFDGVIYRS
:.:: ::::. :: :..:. :: :.:: :. .: :... ..: .: :. : .: .::
NP_001 CGCCRVCARRLGEPCDQLHVCDASQGLVCQPGAGPGGRGALCLLAEDDSSCEVNGRLYRE
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB6 GEKFQPSCKFQCTCRDGQIGCVPRCQLDVLLPEPNCPAPRKVEVPGECCEKWICGPDEED
:: ::: :...: :.:: . ::: :. :: :: .:: ::.::: :.:: .:.:: .
NP_001 GETFQPHCSIRCRCEDGGFTCVPLCSEDVRLPSWDCPHPRRVEVLGKCCPEWVCG--QGG
110 120 130 140 150 160
180 190 200 210 220 230
pF1KB6 SLGGLTLAAYRPEATLGVEVSDSSVNCIEQTTEWTACSKSCGMGFSTRVTNRNRQCEMLK
.:: : : :. . : .: : : .: : :: .::.:..:::.:.:: :..
NP_001 GLGTQPLPAQGPQFSGLVSSLPPGVPCPEWSTAWGPCSTTCGLGMATRVSNQNRFCRLET
170 180 190 200 210 220
240 250 260 270 280 290
pF1KB6 QTRLCMVRPCEQEPEQPTDKKGKKCLRTKKSLKAIHLQFKNCTSLHTYKPRFCGVCSDGR
: :::. :::
NP_001 QRRLCLSRPCPPSRGRSPQNSAF
230 240 250
>>NP_001545 (OMIM: 602369) protein CYR61 precursor [Homo (381 aa)
initn: 1155 init1: 345 opt: 578 Z-score: 492.0 bits: 99.7 E(85289): 1.1e-20
Smith-Waterman score: 1113; 44.2% identity (65.5% similar) in 362 aa overlap (16-343:9-365)
10 20 30 40 50 60
pF1KB6 MQSVQSTSFCLRKQCLCLTFLLLHLLGQVAATQRCPPQCPGQCPATPPTCAPGVRAVLDG
: :. :::: . .: :: : .:: : ::::: : ::
NP_001 MSSRIARALALVVTLLHLTRLALST--CPAAC--HCPLEAPKCAPGVGLVRDG
10 20 30 40
70 80 90 100 110
pF1KB6 CSCCLVCARQRGESCSDLEPCDESSGLYCDRSADPSNQTGICTA-VEGDNCVFDGVIYRS
:.:: :::.: .:.:: .:::...:: :. .:. . ::: : :: : ... ::..
NP_001 CGCCKVCAKQLNEDCSKTQPCDHTKGLECNFGASSTALKGICRAQSEGRPCEYNSRIYQN
50 60 70 80 90 100
120 130 140 150 160 170
pF1KB6 GEKFQPSCKFQCTCRDGQIGCVPRCQLDVLLPEPNCPAPRKVEVPGECCEKWICGPD---
::.:::.:: :::: :: .::.: : .. ::. .:: :: :.: :.:::.:.: :
NP_001 GESFQPNCKHQCTCIDGAVGCIPLCPQELSLPNLGCPNPRLVKVTGQCCEEWVCDEDSIK
110 120 130 140 150 160
180 190 200
pF1KB6 ----EEDSLGG--LTLAAYRPEATLGVEV----SDSSVN--------------------C
..:.: : : . : . : : . :. . ::.. :
NP_001 DPMEDQDGLLGKELGFDASEVELTRNNELIAVGKGSSLKRLPVFGMEPRILYNPLQGQKC
170 180 190 200 210 220
210 220 230 240 250 260
pF1KB6 IEQTTEWTACSKSCGMGFSTRVTNRNRQCEMLKQTRLCMVRPCEQEPEQPTDKKGKKCLR
: ::: :. :::.:: :.:::::: : .:...:.::.: :::: : : . :::::: .
NP_001 IVQTTSWSQCSKTCGTGISTRVTNDNPECRLVKETRICEVRPCGQ-PVYSSLKKGKKCSK
230 240 250 260 270 280
270 280 290 300 310 320
pF1KB6 TKKSLKAIHLQFKNCTSLHTYKPRFCGVCSDGRCCTPHNTKTIQAEFQCSPGQIVKKPVM
:::: . ... . .: :.. :.:..:: : :::::::. :.:.. .:.: :. .: ::
NP_001 TKKSPEPVRFTYAGCLSVKKYRPKYCGSCVDGRCCTPQLTRTVKMRFRCEDGETFSKNVM
290 300 310 320 330 340
330 340 350
pF1KB6 VIGTCTCHTNCPKNNEAFLQELELKTTRGKM
.: .: :. :::. :::
NP_001 MIQSCKCNYNCPHANEAAFPFYRLFNDIHKFRD
350 360 370 380
>>XP_011534525 (OMIM: 208230,603400) PREDICTED: WNT1-ind (160 aa)
initn: 463 init1: 254 opt: 459 Z-score: 398.3 bits: 81.1 E(85289): 1.9e-15
Smith-Waterman score: 459; 41.8% identity (70.5% similar) in 146 aa overlap (206-350:15-159)
180 190 200 210 220 230
pF1KB6 DEEDSLGGLTLAAYRPEATLGVEVSDSSVNCIEQTTEWTACSKSCGMGFSTRVTNRNRQC
:. :.:.:: ::..::::.:.::::.: .:
XP_011 MPAYRNLPLIWKKKCLVQATKWTPCSRTCGMGISNRVTNENSNC
10 20 30 40
240 250 260 270 280 290
pF1KB6 EMLKQTRLCMVRPCEQEPEQPTD-KKGKKCLRTKKSLKAIHLQFKNCTSLHTYKPRFCGV
:: :. :::...::... . ::: : : . :: .. :..:.: ..::: :::.
XP_011 EMRKEKRLCYIQPCDSNILKTIKIPKGKTCQPTFQLSKAEKFVFSGCSSTQSYKPTFCGI
50 60 70 80 90 100
300 310 320 330 340 350
pF1KB6 CSDGRCCTPHNTKTIQAEFQCSPGQIVKKPVMVIGTCTCHTNCPKNNEAFLQELELKTTR
: : ::: :...: : .:.: : .. : .:.:. :: . .. : .::..
XP_011 CLDKRCCIPNKSKMITIQFDCPNEGSFKWKMLWITSCVCQRNCREPGDIF-SELKIL
110 120 130 140 150 160
pF1KB6 GKM
357 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 23:08:34 2016 done: Fri Nov 4 23:08:35 2016
Total Scan time: 8.500 Total Display time: 0.020
Function used was FASTA [36.3.4 Apr, 2011]