FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6495, 285 aa 1>>>pF1KB6495 285 - 285 aa - 285 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.0012+/-0.000387; mu= 16.4518+/- 0.025 mean_var=220.7725+/-47.560, 0's: 0 Z-trim(119.9): 329 B-trim: 3436 in 2/53 Lambda= 0.086318 statistics sampled from 33942 (34374) to 33942 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.735), E-opt: 0.2 (0.403), width: 16 Scan time: 7.920 The best scores are: opt bits E(85289) NP_004490 (OMIM: 602688) heterogeneous nuclear rib ( 285) 1924 251.8 1.1e-66 NP_112556 (OMIM: 602688) heterogeneous nuclear rib ( 332) 1800 236.4 5.4e-62 NP_001003810 (OMIM: 601324) heterogeneous nuclear ( 287) 1172 158.1 1.7e-38 NP_112737 (OMIM: 601324) heterogeneous nuclear rib ( 336) 1116 151.3 2.4e-36 NP_001193929 (OMIM: 607137,609115) heterogeneous n ( 363) 1081 147.0 5.1e-35 NP_002129 (OMIM: 601324) heterogeneous nuclear rib ( 306) 1065 144.9 1.8e-34 NP_112740 (OMIM: 607137,609115) heterogeneous nucl ( 420) 1016 139.0 1.5e-32 NP_112738 (OMIM: 601324) heterogeneous nuclear rib ( 355) 1009 138.0 2.5e-32 NP_001309180 (OMIM: 607897) RNA-binding protein Mu ( 255) 633 90.9 2.6e-18 XP_016879637 (OMIM: 607897) PREDICTED: RNA-binding ( 295) 633 91.0 2.8e-18 NP_620412 (OMIM: 607897) RNA-binding protein Musas ( 328) 633 91.1 3e-18 XP_005257072 (OMIM: 607897) PREDICTED: RNA-binding ( 346) 633 91.1 3.1e-18 XP_005257071 (OMIM: 607897) PREDICTED: RNA-binding ( 346) 633 91.1 3.1e-18 NP_001317180 (OMIM: 605372) heterogeneous nuclear ( 331) 611 88.4 2e-17 NP_001317179 (OMIM: 605372) heterogeneous nuclear ( 331) 611 88.4 2e-17 NP_001317178 (OMIM: 605372) heterogeneous nuclear ( 378) 611 88.5 2.2e-17 NP_919223 (OMIM: 605372) heterogeneous nuclear rib ( 378) 611 88.5 2.2e-17 XP_016874740 (OMIM: 164017,615424,615426) PREDICTE ( 295) 598 86.7 5.8e-17 XP_016867598 (OMIM: 600124,615422) PREDICTED: hete ( 341) 597 86.6 6.8e-17 NP_002128 (OMIM: 600124,615422) heterogeneous nucl ( 341) 597 86.6 6.8e-17 XP_016867599 (OMIM: 600124,615422) PREDICTED: hete ( 341) 597 86.6 6.8e-17 XP_005249786 (OMIM: 600124,615422) PREDICTED: hete ( 353) 597 86.7 7e-17 NP_112533 (OMIM: 600124,615422) heterogeneous nucl ( 353) 597 86.7 7e-17 NP_733839 (OMIM: 607897) RNA-binding protein Musas ( 251) 589 85.4 1.2e-16 NP_002127 (OMIM: 164017,615424,615426) heterogeneo ( 320) 590 85.7 1.2e-16 XP_005268883 (OMIM: 164017,615424,615426) PREDICTE ( 372) 590 85.8 1.3e-16 NP_112420 (OMIM: 164017,615424,615426) heterogeneo ( 372) 590 85.8 1.3e-16 NP_001317176 (OMIM: 605372) heterogeneous nuclear ( 356) 589 85.7 1.4e-16 NP_001317177 (OMIM: 605372) heterogeneous nuclear ( 356) 589 85.7 1.4e-16 NP_001309179 (OMIM: 607897) RNA-binding protein Mu ( 324) 582 84.7 2.4e-16 XP_011536665 (OMIM: 603328) PREDICTED: RNA-binding ( 332) 556 81.5 2.3e-15 XP_011536664 (OMIM: 603328) PREDICTED: RNA-binding ( 343) 556 81.5 2.4e-15 XP_006719466 (OMIM: 603328) PREDICTED: RNA-binding ( 351) 556 81.6 2.4e-15 NP_002433 (OMIM: 603328) RNA-binding protein Musas ( 362) 556 81.6 2.4e-15 XP_011536663 (OMIM: 603328) PREDICTED: RNA-binding ( 362) 556 81.6 2.4e-15 NP_006796 (OMIM: 609409) heterogeneous nuclear rib ( 305) 493 73.6 5.1e-13 NP_031401 (OMIM: 605078,612069) TAR DNA-binding pr ( 414) 406 63.0 1.1e-09 XP_016856353 (OMIM: 605078,612069) PREDICTED: TAR ( 414) 406 63.0 1.1e-09 XP_016856357 (OMIM: 605078,612069) PREDICTED: TAR ( 414) 406 63.0 1.1e-09 XP_016856356 (OMIM: 605078,612069) PREDICTED: TAR ( 414) 406 63.0 1.1e-09 XP_016856354 (OMIM: 605078,612069) PREDICTED: TAR ( 414) 406 63.0 1.1e-09 XP_016856352 (OMIM: 605078,612069) PREDICTED: TAR ( 414) 406 63.0 1.1e-09 XP_016856355 (OMIM: 605078,612069) PREDICTED: TAR ( 414) 406 63.0 1.1e-09 XP_016879636 (OMIM: 607897) PREDICTED: RNA-binding ( 315) 390 60.8 3.8e-09 XP_016882071 (OMIM: 607430) PREDICTED: DAZ-associa ( 327) 312 51.1 3.2e-06 XP_011526209 (OMIM: 607430) PREDICTED: DAZ-associa ( 548) 314 51.7 3.5e-06 XP_011526208 (OMIM: 607430) PREDICTED: DAZ-associa ( 549) 314 51.7 3.6e-06 XP_005259588 (OMIM: 607430) PREDICTED: DAZ-associa ( 406) 311 51.2 3.9e-06 XP_011526211 (OMIM: 607430) PREDICTED: DAZ-associa ( 521) 312 51.5 4.1e-06 XP_011526210 (OMIM: 607430) PREDICTED: DAZ-associa ( 521) 312 51.5 4.1e-06 >>NP_004490 (OMIM: 602688) heterogeneous nuclear ribonuc (285 aa) initn: 1924 init1: 1924 opt: 1924 Z-score: 1318.1 bits: 251.8 E(85289): 1.1e-66 Smith-Waterman score: 1924; 100.0% identity (100.0% similar) in 285 aa overlap (1-285:1-285) 10 20 30 40 50 60 pF1KB6 MSEAGEEQPMETTGATENGHEAVPEGESPAGAGTGAAAGAGGATAAPPSGNQNGAEGDQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MSEAGEEQPMETTGATENGHEAVPEGESPAGAGTGAAAGAGGATAAPPSGNQNGAEGDQI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 NASKNEEDAGKMFVGGLSWDTSKKDLKDYFTKFGEVVDCTIKMDPNTGRSRGFGFILFKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 NASKNEEDAGKMFVGGLSWDTSKKDLKDYFTKFGEVVDCTIKMDPNTGRSRGFGFILFKD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 AASVEKVLDQKEHRLDGRVIDPKKAMAMKKDPVKKIFVGGLNPEATEEKIREYFGEFGEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 AASVEKVLDQKEHRLDGRVIDPKKAMAMKKDPVKKIFVGGLNPEATEEKIREYFGEFGEI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 EAIELPMDPKLNKRRGFVFITFKEEEPVKKVLEKKFHTVSGSKCEIKVAQPKEVYQQQQY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 EAIELPMDPKLNKRRGFVFITFKEEEPVKKVLEKKFHTVSGSKCEIKVAQPKEVYQQQQY 190 200 210 220 230 240 250 260 270 280 pF1KB6 GSGGRGNRNRGNRGSGGGGGGGGQGSTNYGKSQRRGGHQNNYKPY ::::::::::::::::::::::::::::::::::::::::::::: NP_004 GSGGRGNRNRGNRGSGGGGGGGGQGSTNYGKSQRRGGHQNNYKPY 250 260 270 280 >>NP_112556 (OMIM: 602688) heterogeneous nuclear ribonuc (332 aa) initn: 2378 init1: 1774 opt: 1800 Z-score: 1234.0 bits: 236.4 E(85289): 5.4e-62 Smith-Waterman score: 1800; 94.1% identity (97.2% similar) in 288 aa overlap (1-284:1-288) 10 20 30 40 50 60 pF1KB6 MSEAGEEQPMETTGATENGHEAVPEGESPAGAGTGAAAGAGGATAAPPSGNQNGAEGDQI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_112 MSEAGEEQPMETTGATENGHEAVPEGESPAGAGTGAAAGAGGATAAPPSGNQNGAEGDQI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 NASKNEEDAGKMFVGGLSWDTSKKDLKDYFTKFGEVVDCTIKMDPNTGRSRGFGFILFKD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_112 NASKNEEDAGKMFVGGLSWDTSKKDLKDYFTKFGEVVDCTIKMDPNTGRSRGFGFILFKD 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 AASVEKVLDQKEHRLDGRVIDPKKAMAMKKDPVKKIFVGGLNPEATEEKIREYFGEFGEI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_112 AASVEKVLDQKEHRLDGRVIDPKKAMAMKKDPVKKIFVGGLNPEATEEKIREYFGEFGEI 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 EAIELPMDPKLNKRRGFVFITFKEEEPVKKVLEKKFHTVSGSKCEIKVAQPKEVYQQQQY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_112 EAIELPMDPKLNKRRGFVFITFKEEEPVKKVLEKKFHTVSGSKCEIKVAQPKEVYQQQQY 190 200 210 220 230 240 250 260 270 280 pF1KB6 GSGGRGNRNRGNRGSGGGGGGGGQGST---NYGKSQRRG-GHQNNYKPY ::::::::::::::::::::::::... .::. .: :.:..: : NP_112 GSGGRGNRNRGNRGSGGGGGGGGQSQSWNQGYGNYWNQGYGYQQGYGPGYGGYDYSPYGY 250 260 270 280 290 300 NP_112 YGYGPGYDYSQGSTNYGKSQRRGGHQNNYKPY 310 320 330 >>NP_001003810 (OMIM: 601324) heterogeneous nuclear ribo (287 aa) initn: 1135 init1: 561 opt: 1172 Z-score: 811.9 bits: 158.1 E(85289): 1.7e-38 Smith-Waterman score: 1172; 64.6% identity (84.8% similar) in 277 aa overlap (12-285:22-287) 10 20 30 40 50 pF1KB6 MSEAGEEQPMETTGATENGHEAVPEGESPAGAGTGAAAGAGGATAAPPSG ..: :.. :. .: . :.::.::..:.: :... .: NP_001 MSEEQFGGDGAAAAATAAVGGSAGEQEGAMVAATQGAA-AAAGSGAGTGGGTASGGTEGG 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 NQNGAEGDQINASKNEEDAGKMFVGGLSWDTSKKDLKDYFTKFGEVVDCTIKMDPNTGRS . . .:: .:.::::::: ::::.:::::::.::::::::.:::::::::.:.:: :::: NP_001 SAE-SEGAKIDASKNEEDEGKMFIGGLSWDTTKKDLKDYFSKFGEVVDCTLKLDPITGRS 60 70 80 90 100 110 120 130 140 150 160 pF1KB6 RGFGFILFKDAASVEKVLDQKEHRLDGRVIDPKKAMAMK-KDPVKKIFVGGLNPEATEEK :::::.:::.. ::.::.:::::.:.:.:::::.: ::: :.::::::::::.:.. ::: NP_001 RGFGFVLFKESESVDKVMDQKEHKLNGKVIDPKRAKAMKTKEPVKKIFVGGLSPDTPEEK 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB6 IREYFGEFGEIEAIELPMDPKLNKRRGFVFITFKEEEPVKKVLEKKFHTVSGSKCEIKVA :::::: :::.:.:::::: : :::::: ::::::::::::..:::.:.:. :::::::: NP_001 IREYFGGFGEVESIELPMDNKTNKRRGFCFITFKEEEPVKKIMEKKYHNVGLSKCEIKVA 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB6 QPKEVYQQQQ-YGS-GGRGNRNRGNRGSGGGGGGGGQGSTNYGKSQRRGGHQNNYKPY . :: ::::: .:: :: ..: :: ::. ...::: .:::::::.:::: NP_001 MSKEQYQQQQQWGSRGGFAGRARGR---------GGDQQSGYGKVSRRGGHQNSYKPY 240 250 260 270 280 >>NP_112737 (OMIM: 601324) heterogeneous nuclear ribonuc (336 aa) initn: 1052 init1: 561 opt: 1116 Z-score: 773.6 bits: 151.3 E(85289): 2.4e-36 Smith-Waterman score: 1116; 63.2% identity (84.1% similar) in 277 aa overlap (12-285:22-293) 10 20 30 40 50 pF1KB6 MSEAGEEQPMETTGATENGHEAVPEGESPAGAGTGAAAGAGGATAAPPSG ..: :.. :. .: . :.::.::..:.: :... .: NP_112 MSEEQFGGDGAAAAATAAVGGSAGEQEGAMVAATQGAA-AAAGSGAGTGGGTASGGTEGG 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 NQNGAEGDQINASKNEEDAGKMFVGGLSWDTSKKDLKDYFTKFGEVVDCTIKMDPNTGRS . . .:: .:.::::::: ::::.:::::::.::::::::.:::::::::.:.:: :::: NP_112 SAE-SEGAKIDASKNEEDEGKMFIGGLSWDTTKKDLKDYFSKFGEVVDCTLKLDPITGRS 60 70 80 90 100 110 120 130 140 150 160 pF1KB6 RGFGFILFKDAASVEKVLDQKEHRLDGRVIDPKKAMAMK-KDPVKKIFVGGLNPEATEEK :::::.:::.. ::.::.:::::.:.:.:::::.: ::: :.::::::::::.:.. ::: NP_112 RGFGFVLFKESESVDKVMDQKEHKLNGKVIDPKRAKAMKTKEPVKKIFVGGLSPDTPEEK 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB6 IREYFGEFGEIEAIELPMDPKLNKRRGFVFITFKEEEPVKKVLEKKFHTVSGSKCEIKVA :::::: :::.:.:::::: : :::::: ::::::::::::..:::.:.:. :::::::: NP_112 IREYFGGFGEVESIELPMDNKTNKRRGFCFITFKEEEPVKKIMEKKYHNVGLSKCEIKVA 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB6 QPKEVYQQQQ-YGS-GGRGNRNRGNRGSGGGGGGGGQGSTNYGKSQRRGGHQNNYKPY . :: ::::: .:: :: ..: :: :: :: . . .:: .:: .: :.. : . : NP_112 MSKEQYQQQQQWGSRGGFAGRARG-RG-GGPSQNWNQGYSNYW-NQGYGNYGYNSQGYGG 240 250 260 270 280 290 NP_112 YGGYDYTGYNNYYGYGDYSNQQSGYGKVSRRGGHQNSYKPY 300 310 320 330 >>NP_001193929 (OMIM: 607137,609115) heterogeneous nucle (363 aa) initn: 589 init1: 525 opt: 1081 Z-score: 749.7 bits: 147.0 E(85289): 5.1e-35 Smith-Waterman score: 1081; 69.2% identity (86.8% similar) in 234 aa overlap (55-285:133-363) 30 40 50 60 70 80 pF1KB6 EGESPAGAGTGAAAGAGGATAAPPSGNQNGAEGDQINASKNEEDAGKMFVGGLSWDTSKK :::..::::::..: ::::.:::::::::: NP_001 AATRTARQHPPADSSVTMEDMNEYSNIEEFAEGSKINASKNQQDDGKMFIGGLSWDTSKK 110 120 130 140 150 160 90 100 110 120 130 140 pF1KB6 DLKDYFTKFGEVVDCTIKMDPNTGRSRGFGFILFKDAASVEKVLDQKEHRLDGRVIDPKK :: .:...:::::::::: :: :::::::::.::::::::.:::. :::.:::..::::. NP_001 DLTEYLSRFGEVVDCTIKTDPVTGRSRGFGFVLFKDAASVDKVLELKEHKLDGKLIDPKR 170 180 190 200 210 220 150 160 170 180 190 200 pF1KB6 AMAMK-KDPVKKIFVGGLNPEATEEKIREYFGEFGEIEAIELPMDPKLNKRRGFVFITFK : :.: :.: ::.:::::.:...::.:.:::: ::::: :::::: : :.:::: :::. NP_001 AKALKGKEPPKKVFVGGLSPDTSEEQIKEYFGAFGEIENIELPMDTKTNERRGFCFITYT 230 240 250 260 270 280 210 220 230 240 250 260 pF1KB6 EEEPVKKVLEKKFHTVSGSKCEIKVAQPKEVY-QQQQYGSGGRGNRNRGNRGSGGGGGGG .::::::.::...: ....::::::::::::: :::: .:::: :.:: : : : NP_001 DEEPVKKLLESRYHQIGSGKCEIKVAQPKEVYRQQQQQQKGGRGA-AAGGRG-GTRGRGR 290 300 310 320 330 340 270 280 pF1KB6 GQGSTNYGKSQRRGG-HQNNYKPY :: :: :::..: :: :::::.:: NP_001 GQQST-YGKASRGGGNHQNNYQPY 350 360 >>NP_002129 (OMIM: 601324) heterogeneous nuclear ribonuc (306 aa) initn: 1075 init1: 474 opt: 1065 Z-score: 739.7 bits: 144.9 E(85289): 1.8e-34 Smith-Waterman score: 1124; 60.5% identity (79.4% similar) in 296 aa overlap (12-285:22-306) 10 20 30 40 50 pF1KB6 MSEAGEEQPMETTGATENGHEAVPEGESPAGAGTGAAAGAGGATAAPPSG ..: :.. :. .: . :.::.::..:.: :... .: NP_002 MSEEQFGGDGAAAAATAAVGGSAGEQEGAMVAATQGAA-AAAGSGAGTGGGTASGGTEGG 10 20 30 40 50 60 70 80 90 pF1KB6 NQNGAEGDQINASKNEEDAG-------------------KMFVGGLSWDTSKKDLKDYFT . . .:: .:.::::::: : :::.:::::::.::::::::. NP_002 SAE-SEGAKIDASKNEEDEGHSNSSPRHSEAATAQREEWKMFIGGLSWDTTKKDLKDYFS 60 70 80 90 100 110 100 110 120 130 140 150 pF1KB6 KFGEVVDCTIKMDPNTGRSRGFGFILFKDAASVEKVLDQKEHRLDGRVIDPKKAMAMK-K :::::::::.:.:: :::::::::.:::.. ::.::.:::::.:.:.:::::.: ::: : NP_002 KFGEVVDCTLKLDPITGRSRGFGFVLFKESESVDKVMDQKEHKLNGKVIDPKRAKAMKTK 120 130 140 150 160 170 160 170 180 190 200 210 pF1KB6 DPVKKIFVGGLNPEATEEKIREYFGEFGEIEAIELPMDPKLNKRRGFVFITFKEEEPVKK .::::::::::.:.. ::::::::: :::.:.:::::: : :::::: :::::::::::: NP_002 EPVKKIFVGGLSPDTPEEKIREYFGGFGEVESIELPMDNKTNKRRGFCFITFKEEEPVKK 180 190 200 210 220 230 220 230 240 250 260 pF1KB6 VLEKKFHTVSGSKCEIKVAQPKEVYQQQQ-YGS-GGRGNRNRGNRGSGGGGGGGGQGSTN ..:::.:.:. ::::::::. :: ::::: .:: :: ..: :: ::. ... NP_002 IMEKKYHNVGLSKCEIKVAMSKEQYQQQQQWGSRGGFAGRARGR---------GGDQQSG 240 250 260 270 280 270 280 pF1KB6 YGKSQRRGGHQNNYKPY ::: .:::::::.:::: NP_002 YGKVSRRGGHQNSYKPY 290 300 >>NP_112740 (OMIM: 607137,609115) heterogeneous nuclear (420 aa) initn: 986 init1: 513 opt: 1016 Z-score: 705.4 bits: 139.0 E(85289): 1.5e-32 Smith-Waterman score: 1016; 65.0% identity (83.8% similar) in 234 aa overlap (55-282:133-365) 30 40 50 60 70 80 pF1KB6 EGESPAGAGTGAAAGAGGATAAPPSGNQNGAEGDQINASKNEEDAGKMFVGGLSWDTSKK :::..::::::..: ::::.:::::::::: NP_112 AATRTARQHPPADSSVTMEDMNEYSNIEEFAEGSKINASKNQQDDGKMFIGGLSWDTSKK 110 120 130 140 150 160 90 100 110 120 130 140 pF1KB6 DLKDYFTKFGEVVDCTIKMDPNTGRSRGFGFILFKDAASVEKVLDQKEHRLDGRVIDPKK :: .:...:::::::::: :: :::::::::.::::::::.:::. :::.:::..::::. NP_112 DLTEYLSRFGEVVDCTIKTDPVTGRSRGFGFVLFKDAASVDKVLELKEHKLDGKLIDPKR 170 180 190 200 210 220 150 160 170 180 190 200 pF1KB6 AMAMK-KDPVKKIFVGGLNPEATEEKIREYFGEFGEIEAIELPMDPKLNKRRGFVFITFK : :.: :.: ::.:::::.:...::.:.:::: ::::: :::::: : :.:::: :::. NP_112 AKALKGKEPPKKVFVGGLSPDTSEEQIKEYFGAFGEIENIELPMDTKTNERRGFCFITYT 230 240 250 260 270 280 210 220 230 240 250 260 pF1KB6 EEEPVKKVLEKKFHTVSGSKCEIKVAQPKEVY-QQQQYGSGGRGNRNRGNRGSGGGGGGG .::::::.::...: ....::::::::::::: :::: .:::: : :. : : : NP_112 DEEPVKKLLESRYHQIGSGKCEIKVAQPKEVYRQQQQQQKGGRGAAAGGRGGTRGRGRGQ 290 300 310 320 330 340 270 280 pF1KB6 GQ----GSTNYGKSQRRGGHQNNYKPY :: : .:: .: :.... : NP_112 GQNWNQGFNNY-YDQGYGNYNSAYGGDQNYSGYGGYDYTGYNYGNYGYGQGYADYSGQQS 350 360 370 380 390 400 >>NP_112738 (OMIM: 601324) heterogeneous nuclear ribonuc (355 aa) initn: 992 init1: 505 opt: 1009 Z-score: 701.4 bits: 138.0 E(85289): 2.5e-32 Smith-Waterman score: 1068; 59.1% identity (78.7% similar) in 296 aa overlap (12-285:22-312) 10 20 30 40 50 pF1KB6 MSEAGEEQPMETTGATENGHEAVPEGESPAGAGTGAAAGAGGATAAPPSG ..: :.. :. .: . :.::.::..:.: :... .: NP_112 MSEEQFGGDGAAAAATAAVGGSAGEQEGAMVAATQGAA-AAAGSGAGTGGGTASGGTEGG 10 20 30 40 50 60 70 80 90 pF1KB6 NQNGAEGDQINASKNEEDAG-------------------KMFVGGLSWDTSKKDLKDYFT . . .:: .:.::::::: : :::.:::::::.::::::::. NP_112 SAE-SEGAKIDASKNEEDEGHSNSSPRHSEAATAQREEWKMFIGGLSWDTTKKDLKDYFS 60 70 80 90 100 110 100 110 120 130 140 150 pF1KB6 KFGEVVDCTIKMDPNTGRSRGFGFILFKDAASVEKVLDQKEHRLDGRVIDPKKAMAMK-K :::::::::.:.:: :::::::::.:::.. ::.::.:::::.:.:.:::::.: ::: : NP_112 KFGEVVDCTLKLDPITGRSRGFGFVLFKESESVDKVMDQKEHKLNGKVIDPKRAKAMKTK 120 130 140 150 160 170 160 170 180 190 200 210 pF1KB6 DPVKKIFVGGLNPEATEEKIREYFGEFGEIEAIELPMDPKLNKRRGFVFITFKEEEPVKK .::::::::::.:.. ::::::::: :::.:.:::::: : :::::: :::::::::::: NP_112 EPVKKIFVGGLSPDTPEEKIREYFGGFGEVESIELPMDNKTNKRRGFCFITFKEEEPVKK 180 190 200 210 220 230 220 230 240 250 260 pF1KB6 VLEKKFHTVSGSKCEIKVAQPKEVYQQQQ-YGS-GGRGNRNRGNRGSGGGGGGGGQGSTN ..:::.:.:. ::::::::. :: ::::: .:: :: ..: :: :: :: . . .:: .: NP_112 IMEKKYHNVGLSKCEIKVAMSKEQYQQQQQWGSRGGFAGRARG-RG-GGPSQNWNQGYSN 240 250 260 270 280 290 270 280 pF1KB6 YGKSQRRGGHQNNYKPY : .: :.. : . : NP_112 YW-NQGYGNYGYNSQGYGGYGGYDYTGYNNYYGYGDYSNQQSGYGKVSRRGGHQNSYKPY 300 310 320 330 340 350 >>NP_001309180 (OMIM: 607897) RNA-binding protein Musash (255 aa) initn: 624 init1: 389 opt: 633 Z-score: 449.7 bits: 90.9 E(85289): 2.6e-18 Smith-Waterman score: 633; 44.6% identity (69.3% similar) in 231 aa overlap (53-276:4-229) 30 40 50 60 70 80 pF1KB6 VPEGESPAGAGTGAAAGAGGATAAPPSGNQNGAEGDQINASKNEEDAGKMFVGGLSWDTS ::..: . .:. ...: ::::.:::::.:: NP_001 MEANGSQGTSGSANDSQHDPGKMFIGGLSWQTS 10 20 30 90 100 110 120 130 140 pF1KB6 KKDLKDYFTKFGEVVDCTIKMDPNTGRSRGFGFILFKDAASVEKVLDQKEHRLDGRVIDP .:.:::.::::. .: . ::.: :::::::. : : :::.::: : .:.::...::: NP_001 PDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLGQPHHELDSKTIDP 40 50 60 70 80 90 150 160 170 180 190 pF1KB6 KKAMAMKKDP-----VKKIFVGGLNPEATEEKIREYFGEFGEIEAIELPMDPKLNKRRGF : :. . .: .::::::::. ... : ...:: .::..: : .: :..::: NP_001 KVAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHRGF 100 110 120 130 140 150 200 210 220 230 240 250 pF1KB6 VFITFKEEEPVKKVLEKKFHTVSGSKCEIKVAQPKEVYQQQQYGSGGRGNRNRGNRGSGG :.::..:. :.:: : .:: .... : : ::::::. . : :: : :: . NP_001 GFVTFENEDVVEKVCEIHFHEINNKMVECKKAQPKEVM----FPPGTRG-RARGLPYTMD 160 170 180 190 200 260 270 280 pF1KB6 GG--GGGGQGSTNYGKSQRRGGHQNNYKPY . : : : :. . :: NP_001 AFMLGMGMLGYPNFVATYGRGYPGFAPSYGYQFPDYLPVSQDIIFIN 210 220 230 240 250 >>XP_016879637 (OMIM: 607897) PREDICTED: RNA-binding pro (295 aa) initn: 624 init1: 389 opt: 633 Z-score: 449.1 bits: 91.0 E(85289): 2.8e-18 Smith-Waterman score: 633; 44.6% identity (69.3% similar) in 231 aa overlap (53-276:4-229) 30 40 50 60 70 80 pF1KB6 VPEGESPAGAGTGAAAGAGGATAAPPSGNQNGAEGDQINASKNEEDAGKMFVGGLSWDTS ::..: . .:. ...: ::::.:::::.:: XP_016 MEANGSQGTSGSANDSQHDPGKMFIGGLSWQTS 10 20 30 90 100 110 120 130 140 pF1KB6 KKDLKDYFTKFGEVVDCTIKMDPNTGRSRGFGFILFKDAASVEKVLDQKEHRLDGRVIDP .:.:::.::::. .: . ::.: :::::::. : : :::.::: : .:.::...::: XP_016 PDSLRDYFSKFGEIRECMVMRDPTTKRSRGFGFVTFADPASVDKVLGQPHHELDSKTIDP 40 50 60 70 80 90 150 160 170 180 190 pF1KB6 KKAMAMKKDP-----VKKIFVGGLNPEATEEKIREYFGEFGEIEAIELPMDPKLNKRRGF : :. . .: .::::::::. ... : ...:: .::..: : .: :..::: XP_016 KVAFPRRAQPKMVTRTKKIFVGGLSANTVVEDVKQYFEQFGKVEDAMLMFDKTTNRHRGF 100 110 120 130 140 150 200 210 220 230 240 250 pF1KB6 VFITFKEEEPVKKVLEKKFHTVSGSKCEIKVAQPKEVYQQQQYGSGGRGNRNRGNRGSGG :.::..:. :.:: : .:: .... : : ::::::. . : :: : :: . XP_016 GFVTFENEDVVEKVCEIHFHEINNKMVECKKAQPKEVM----FPPGTRG-RARGLPYTMD 160 170 180 190 200 260 270 280 pF1KB6 GG--GGGGQGSTNYGKSQRRGGHQNNYKPY . : : : :. . :: XP_016 AFMLGMGMLGYPNFVATYGRGYPGFAPSYGYQFPGFPAAAYGPVAAAAVAAARGSGSAHL 210 220 230 240 250 260 285 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 21:03:26 2016 done: Fri Nov 4 21:03:27 2016 Total Scan time: 7.920 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]