FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6496, 358 aa 1>>>pF1KB6496 358 - 358 aa - 358 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.4881+/-0.000363; mu= 15.7892+/- 0.022 mean_var=72.1713+/-14.123, 0's: 0 Z-trim(114.0): 116 B-trim: 105 in 1/57 Lambda= 0.150970 statistics sampled from 23477 (23599) to 23477 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.654), E-opt: 0.2 (0.277), width: 16 Scan time: 5.550 The best scores are: opt bits E(85289) NP_057390 (OMIM: 611341) dnaJ homolog subfamily B ( 358) 2424 537.1 2.2e-152 NP_705842 (OMIM: 610263,617091) dnaJ homolog subfa ( 316) 464 110.2 6.4e-24 XP_011543306 (OMIM: 610263,617091) PREDICTED: dnaJ ( 350) 401 96.5 9.4e-20 NP_006136 (OMIM: 604572) dnaJ homolog subfamily B ( 340) 342 83.7 6.8e-16 NP_005871 (OMIM: 611322) dnaJ homolog subfamily A ( 412) 341 83.5 9.2e-16 NP_001258510 (OMIM: 607987) dnaJ homolog subfamily ( 747) 337 82.8 2.8e-15 NP_061854 (OMIM: 607987) dnaJ homolog subfamily C ( 793) 337 82.8 2.9e-15 NP_001128582 (OMIM: 608382) dnaJ homolog subfamily ( 453) 329 80.9 6.1e-15 NP_005138 (OMIM: 608382) dnaJ homolog subfamily A ( 480) 329 80.9 6.4e-15 XP_006722796 (OMIM: 604572) PREDICTED: dnaJ homolo ( 240) 325 79.9 6.6e-15 XP_011526258 (OMIM: 604572) PREDICTED: dnaJ homolo ( 240) 325 79.9 6.6e-15 XP_006722797 (OMIM: 604572) PREDICTED: dnaJ homolo ( 240) 325 79.9 6.6e-15 NP_001300893 (OMIM: 604572) dnaJ homolog subfamily ( 240) 325 79.9 6.6e-15 NP_001287843 (OMIM: 604572) dnaJ homolog subfamily ( 240) 325 79.9 6.6e-15 XP_016867122 (OMIM: 603511,611332) PREDICTED: dnaJ ( 211) 321 79.0 1.1e-14 NP_005485 (OMIM: 603511,611332) dnaJ homolog subfa ( 241) 321 79.0 1.2e-14 XP_006715886 (OMIM: 603511,611332) PREDICTED: dnaJ ( 257) 321 79.0 1.3e-14 NP_036460 (OMIM: 602634) dnaJ homolog subfamily B ( 223) 320 78.8 1.3e-14 NP_490647 (OMIM: 603511,611332) dnaJ homolog subfa ( 326) 321 79.1 1.6e-14 XP_005249573 (OMIM: 603511,611332) PREDICTED: dnaJ ( 334) 321 79.1 1.6e-14 XP_011514006 (OMIM: 603511,611332) PREDICTED: dnaJ ( 334) 321 79.1 1.6e-14 XP_005249572 (OMIM: 603511,611332) PREDICTED: dnaJ ( 334) 321 79.1 1.6e-14 NP_001300968 (OMIM: 602837) dnaJ homolog subfamily ( 240) 310 76.6 6.4e-14 NP_001530 (OMIM: 602837) dnaJ homolog subfamily A ( 397) 310 76.7 9.7e-14 NP_060096 (OMIM: 608376) dnaJ homolog subfamily B ( 409) 307 76.1 1.6e-13 XP_005269989 (OMIM: 608376) PREDICTED: dnaJ homolo ( 409) 307 76.1 1.6e-13 NP_001002762 (OMIM: 608376) dnaJ homolog subfamily ( 409) 307 76.1 1.6e-13 XP_005269988 (OMIM: 608376) PREDICTED: dnaJ homolo ( 411) 307 76.1 1.6e-13 NP_001304032 (OMIM: 611327) dnaJ homolog subfamily ( 77) 296 73.3 2.1e-13 NP_001034639 (OMIM: 604139,614881,617017) dnaJ hom ( 277) 300 74.5 3.2e-13 NP_006727 (OMIM: 604139,614881,617017) dnaJ homolo ( 324) 300 74.5 3.7e-13 XP_016873165 (OMIM: 610263,617091) PREDICTED: dnaJ ( 258) 292 72.7 1e-12 XP_016873166 (OMIM: 610263,617091) PREDICTED: dnaJ ( 258) 292 72.7 1e-12 XP_016873167 (OMIM: 610263,617091) PREDICTED: dnaJ ( 258) 292 72.7 1e-12 XP_016873164 (OMIM: 610263,617091) PREDICTED: dnaJ ( 258) 292 72.7 1e-12 XP_011543309 (OMIM: 610263,617091) PREDICTED: dnaJ ( 258) 292 72.7 1e-12 XP_011543311 (OMIM: 610263,617091) PREDICTED: dnaJ ( 258) 292 72.7 1e-12 NP_001304029 (OMIM: 611327) dnaJ homolog subfamily ( 297) 289 72.1 1.8e-12 NP_001304028 (OMIM: 611327) dnaJ homolog subfamily ( 337) 289 72.1 2e-12 NP_008965 (OMIM: 611327) dnaJ homolog subfamily B ( 337) 289 72.1 2e-12 NP_660157 (OMIM: 611336) dnaJ homolog subfamily B ( 309) 287 71.7 2.5e-12 XP_011527351 (OMIM: 611203) PREDICTED: dnaJ homolo ( 198) 284 70.9 2.8e-12 XP_011527350 (OMIM: 611203) PREDICTED: dnaJ homolo ( 198) 284 70.9 2.8e-12 NP_079495 (OMIM: 611203) dnaJ homolog subfamily C ( 198) 284 70.9 2.8e-12 XP_011515922 (OMIM: 613945) PREDICTED: dnaJ homolo ( 180) 279 69.8 5.4e-12 NP_001304030 (OMIM: 611327) dnaJ homolog subfamily ( 222) 280 70.1 5.5e-12 NP_001304031 (OMIM: 611327) dnaJ homolog subfamily ( 222) 280 70.1 5.5e-12 NP_149096 (OMIM: 613945) dnaJ homolog subfamily C ( 199) 279 69.8 5.9e-12 XP_011515920 (OMIM: 613945) PREDICTED: dnaJ homolo ( 199) 279 69.8 5.9e-12 NP_699161 (OMIM: 611337) dnaJ homolog subfamily B ( 232) 272 68.3 1.9e-11 >>NP_057390 (OMIM: 611341) dnaJ homolog subfamily B memb (358 aa) initn: 2424 init1: 2424 opt: 2424 Z-score: 2856.8 bits: 537.1 E(85289): 2.2e-152 Smith-Waterman score: 2424; 99.7% identity (100.0% similar) in 358 aa overlap (1-358:1-358) 10 20 30 40 50 60 pF1KB6 MAPQNLSTFCLLLLYLIGAVIAGRDFYKILGVPRSASIKDIKKAYRKLALQLHPDRNPDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 MAPQNLSTFCLLLLYLIGAVIAGRDFYKILGVPRSASIKDIKKAYRKLALQLHPDRNPDD 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 PQAQEKFQDLGAAYEVLSDSEKRKQYDTYGEEGLKDGHQSSHGDIFSHFFGDFGFMFGGT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 PQAQEKFQDLGAAYEVLSDSEKRKQYDTYGEEGLKDGHQSSHGDIFSHFFGDFGFMFGGT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 PRQQDRNIPRGSDIIVDLEVTLEEVYAGNFVEVVRNKPVARQAPGKRKCNCRQEMRTTQL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 PRQQDRNIPRGSDIIVDLEVTLEEVYAGNFVEVVRNKPVARQAPGKRKCNCRQEMRTTQL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 GPGRFQMTQEVVCDECPNVKLVNEERTLEVEIEPGVRDGMEYPFIGEGEPHVDGEPGDLR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 GPGRFQMTQEVVCDECPNVKLVNEERTLEVEIEPGVRDGMEYPFIGEGEPHVDGEPGDLR 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 FRIKVVKHPIFERRGDDLYTNVTVSLVESLVGFEMDITHLDGHKVHISRDKITRPGAKLW :::::::::::::::::::::::.:::::::::::::::::::::::::::::::::::: NP_057 FRIKVVKHPIFERRGDDLYTNVTISLVESLVGFEMDITHLDGHKVHISRDKITRPGAKLW 250 260 270 280 290 300 310 320 330 340 350 pF1KB6 KKGEGLPNFDNNNIKGSLIITFDVDFPKEQLTEEAREGIKQLLKQGSVQKVYNGLQGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 KKGEGLPNFDNNNIKGSLIITFDVDFPKEQLTEEAREGIKQLLKQGSVQKVYNGLQGY 310 320 330 340 350 >>NP_705842 (OMIM: 610263,617091) dnaJ homolog subfamily (316 aa) initn: 392 init1: 218 opt: 464 Z-score: 550.4 bits: 110.2 E(85289): 6.4e-24 Smith-Waterman score: 464; 29.5% identity (62.5% similar) in 325 aa overlap (23-343:2-314) 10 20 30 40 50 60 pF1KB6 MAPQNLSTFCLLLLYLIGAVIAGRDFYKILGVPRSASIKDIKKAYRKLALQLHPDRNPDD :.:.:..::. :.. .::.:::.:::. :: .. .. NP_705 MGQDYYSVLGITRNSEDAQIKQAYRRLALKHHPLKS-NE 10 20 30 70 80 90 100 110 120 pF1KB6 PQAQEKFQDLGAAYEVLSDSEKRKQYDTYGEEGLKDGHQSSHGDIFSHFFGDFGFMFGGT :.. : :.... ::.:::: :: :: .:::::: : : :. :..: : NP_705 PSSAEIFRQIAEAYDVLSDPMKRGIYDKFGEEGLKGGIPLEFG---SQTPWTTGYVFHGK 40 50 60 70 80 90 130 140 150 160 170 pF1KB6 PRQQDRNIPRGSDIIVDL-EVTLEEVYAGNFVEVVRNKPVARQAPGKRKCNCRQEMRTTQ :.. ... :.. . .. .. :: :: . ... : .: : .. . .. NP_705 PEKVFHEFFGGNNPFSEFFDAEGSEVDL-NFGGL-QGRGVKKQDPQVER-DLYLSLEDLF 100 110 120 130 140 150 180 190 200 210 220 230 pF1KB6 LG-PGRFQMTQEVVCDECPNVKLVNEERTLEVEIEPGVRDGMEYPFIGEGEPHVDGEPGD .: .......:. .. . . ... : ....:: :.: . : ::. . :.: NP_705 FGCTKKIKISRRVLNEDGYSSTI--KDKILTIDVKPGWRQGTRITFEKEGDQGPNIIPAD 160 170 180 190 200 210 240 250 260 270 280 290 pF1KB6 LRFRIKVVKHPIFERRGDDLYTNVTVSLVESLVGFEMDITHLDGHKVHISRDKITRPGAK . : .: :: :.:..:.:. . : ..:. ... :: . ..: . : .: : NP_705 IIFIVKEKLHPRFRRENDNLFFVNPIPLGKALTCCTVEVRTLDDRLLNIPINDIIHP--K 220 230 240 250 260 300 310 320 330 340 350 pF1KB6 LWKK--GEGLPNFDNNNIKGSLIITFDVDFPKEQLTEEAREGIKQLLKQGSVQKVYNGLQ .:: :::.: .. . ::.:.: ::..:: .:: . .. ..: : NP_705 YFKKVPGEGMPLPEDPTKKGDLFIFFDIQFPT-RLTPQKKQMLRQALLT 270 280 290 300 310 pF1KB6 GY >>XP_011543306 (OMIM: 610263,617091) PREDICTED: dnaJ hom (350 aa) initn: 355 init1: 218 opt: 401 Z-score: 475.6 bits: 96.5 E(85289): 9.4e-20 Smith-Waterman score: 401; 27.7% identity (60.2% similar) in 314 aa overlap (36-343:49-348) 10 20 30 40 50 60 pF1KB6 LSTFCLLLLYLIGAVIAGRDFYKILGVPRSASIKDIKKAYRKLALQLHPDRNPDDPQAQE .. .: . ::.:::. :: .. ..:.. : XP_011 QCPALGLELDAATPGPPSLLDRGVNIHLEHSTAEDKDQRYRRLALKHHPLKS-NEPSSAE 20 30 40 50 60 70 70 80 90 100 110 120 pF1KB6 KFQDLGAAYEVLSDSEKRKQYDTYGEEGLKDGHQSSHGDIFSHFFGDFGFMFGGTPRQQD :.... ::.:::: :: :: .:::::: : : :. :..: : :.. XP_011 IFRQIAEAYDVLSDPMKRGIYDKFGEEGLKGGIPLEFG---SQTPWTTGYVFHGKPEKVF 80 90 100 110 120 130 130 140 150 160 170 180 pF1KB6 RNIPRGSDII---VDLEVTLEEVYAGNFVEVVRNKPVARQAPGKRKCNCRQEMRTTQLG- ... :.. . : : . .. :.. ... : .: : .. . .. .: XP_011 HEFFGGNNPFSEFFDAEGSEVDLNFGGL----QGRGVKKQDPQVER-DLYLSLEDLFFGC 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 PGRFQMTQEVVCDECPNVKLVNEERTLEVEIEPGVRDGMEYPFIGEGEPHVDGEPGDLRF .......:. .. . . ... : ....:: :.: . : ::. . :.:. : XP_011 TKKIKISRRVLNEDGYSSTI--KDKILTIDVKPGWRQGTRITFEKEGDQGPNIIPADIIF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 RIKVVKHPIFERRGDDLYTNVTVSLVESLVGFEMDITHLDGHKVHISRDKITRPGAKLWK .: :: :.:..:.:. . : ..:. ... :: . ..: . : .: : .: XP_011 IVKEKLHPRFRRENDNLFFVNPIPLGKALTCCTVEVRTLDDRLLNIPINDIIHP--KYFK 250 260 270 280 290 300 310 320 330 340 350 pF1KB6 K--GEGLPNFDNNNIKGSLIITFDVDFPKEQLTEEAREGIKQLLKQGSVQKVYNGLQGY : :::.: .. . ::.:.: ::..:: .:: . .. ..: : XP_011 KVPGEGMPLPEDPTKKGDLFIFFDIQFPT-RLTPQKKQMLRQALLT 310 320 330 340 350 >>NP_006136 (OMIM: 604572) dnaJ homolog subfamily B memb (340 aa) initn: 587 init1: 271 opt: 342 Z-score: 406.3 bits: 83.7 E(85289): 6.8e-16 Smith-Waterman score: 587; 32.9% identity (62.7% similar) in 343 aa overlap (23-343:2-338) 10 20 30 40 50 60 pF1KB6 MAPQNLSTFCLLLLYLIGAVIAGRDFYKILGVPRSASIKDIKKAYRKLALQLHPDRNPDD :.:.:. ::. :.:: ..::.:::. ::. :::.: . NP_006 MGKDYYQTLGLARGASDEEIKRAYRRQALRYHPDKNKE- 10 20 30 70 80 90 100 110 pF1KB6 PQAQEKFQDLGAAYEVLSDSEKRKQYDTYGEEGLKDGHQS------SHGDIFSH-FFGD- : :.:::.... ::.:::: .::. .: ::::::: . : ..: ::. : :: NP_006 PGAEEKFKEIAEAYDVLSDPRKREIFDRYGEEGLKGSGPSGGSGGGANGTSFSYTFHGDP 40 50 60 70 80 90 120 130 140 150 160 pF1KB6 ---FGFMFGG-TPRQQ---DRNIPRGSDIIVDLEVTLEEVYAGNFVEVVRNKPVARQAPG :. .::: .: . .:: .: :: : . . :.:..: .. . : :. NP_006 HAMFAEFFGGRNPFDTFFGQRNGEEGMDI--DDPFSGFPMGMGGFTNVNFGRSRSAQEPA 100 110 120 130 140 150 170 180 190 200 210 pF1KB6 KRKCN--CRQEMRTT--QLGPG---RFQMTQEVVCDECPNVKLVNEERTLEVEIEPGVRD ..: . ...:.. .. : ....... . . ... ::.. : .:.. : .. NP_006 RKKQDPPVTHDLRVSLEEIYSGCTKKMKISHKRLNPDGKSIR--NEDKILTIEVKKGWKE 160 170 180 190 200 210 220 230 240 250 260 270 pF1KB6 GMEYPFIGEGEPHVDGEPGDLRFRIKVVKHPIFERRGDDLYTNVTVSLVESLVGFEMDIT : . : ::. .. :.:. : .: : ::.: :.:. . .:: :.: : ... NP_006 GTKITFPKEGDQTSNNIPADIVFVLKDKPHNIFKRDGSDVIYPARISLREALCGCTVNVP 220 230 240 250 260 270 280 290 300 310 320 330 pF1KB6 HLDGHKVHISRDKITRPGAKLWKKGEGLPNFDNNNIKGSLIITFDVDFPKEQLTEEAREG :::. . . . ::: . ::::: . . .:.::: :.: :: :.. . .: NP_006 TLDGRTIPVVFKDVIRPGMRRKVPGEGLPLPKTPEKRGDLIIEFEVIFP-ERIPQTSRTV 280 290 300 310 320 330 340 350 pF1KB6 IKQLLKQGSVQKVYNGLQGY ..:.: NP_006 LEQVLPI 340 >>NP_005871 (OMIM: 611322) dnaJ homolog subfamily A memb (412 aa) initn: 602 init1: 206 opt: 341 Z-score: 403.9 bits: 83.5 E(85289): 9.2e-16 Smith-Waterman score: 715; 38.5% identity (65.0% similar) in 343 aa overlap (19-328:2-339) 10 20 30 40 50 60 pF1KB6 MAPQNLSTFCLLLLYLIGAVIAGRDFYKILGVPRSASIKDIKKAYRKLALQLHPDRNPDD : .: .: ::::: .:: ...:::::::: . :::.::. NP_005 MANVADTKLYDILGVPPGASENELKKAYRKLAKEYHPDKNPN- 10 20 30 40 70 80 90 100 110 pF1KB6 PQAQEKFQDLGAAYEVLSDSEKRKQYDTYGEEGLKDGHQSSHG--DIFSHFFGD--FGFM : .::.... ::::::. :::. :: :::.::..: .. : :::::.:: :::: NP_005 --AGDKFKEISFAYEVLSNPEKRELYDRYGEQGLREGSGGGGGMDDIFSHIFGGGLFGFM 50 60 70 80 90 100 120 130 140 150 160 pF1KB6 FGGTPRQQDRNIPRGSDIIVDLEVTLEEVYAGNFVEVVRNKPVARQA----PGK----RK :. :... . :: :.. :.:.::..: :. ... .: : .: :: .: NP_005 -GNQSRSRN-GRRRGEDMMHPLKVSLEDLYNGKTTKLQLSKNVLCSACSGQGGKSGAVQK 110 120 130 140 150 170 180 190 200 pF1KB6 CN-CRQE---MRTTQLGPGRFQMTQ----------EVV-----CDECPNVKLVNEERTLE :. :: . . ::.:: :. : ::. : .: . :...: . :: NP_005 CSACRGRGVRIMIRQLAPGMVQQMQSVCSDCNGEGEVINEKDRCKKCEGKKVIKEVKILE 160 170 180 190 200 210 210 220 230 240 250 260 pF1KB6 VEIEPGVRDGMEYPFIGEGEPHVDGEPGDLRFRIKVVKHPIFERRGDDLYTNVTVSLVES :... :.. :.. : ::.. ::::. . .. .: .:.: :.::. . ..:::. NP_005 VHVDKGMKHGQRITFTGEADQAPGVEPGDIVLLLQEKEHEVFQRDGNDLHMTYKIGLVEA 220 230 240 250 260 270 270 280 290 300 310 320 pF1KB6 LVGFEMDITHLDGHKVHISRD--KITRPGAKLWKKGEGLPNFDNNNIKGSLIITFDVDFP : ::.. . ::::... .. :. .:: .:::.:.. : ::.: : :::.:: NP_005 LCGFQFTFKHLDGRQIVVKYPPGKVIEPGCVRVVRGEGMPQYRNPFEKGDLYIKFDVQFP 280 290 300 310 320 330 330 340 350 pF1KB6 KEQLTEEAREGIKQLLKQGSVQKVYNGLQGY . NP_005 ENNWINPDKLSELEDLLPSRPEVPNIIGETEEVELQEFDSTRGSGGGQRREAYNDSSDEE 340 350 360 370 380 390 >>NP_001258510 (OMIM: 607987) dnaJ homolog subfamily C m (747 aa) initn: 290 init1: 290 opt: 337 Z-score: 395.4 bits: 82.8 E(85289): 2.8e-15 Smith-Waterman score: 337; 42.5% identity (78.8% similar) in 113 aa overlap (9-121:19-129) 10 20 30 40 50 pF1KB6 MAPQNLSTFCLLLLYLIGAVIAGRDFYKILGVPRSASIKDIKKAYRKLAL .:.:..:. : . .:::..::: ..:: ..:..:..:::: NP_001 MGVWLNKDDYIRDLKRIILCFLIVYMAILVGTDQDFYSLLGVSKTASSREIRQAFKKLAL 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 QLHPDRNPDDPQAQEKFQDLGAAYEVLSDSEKRKQYDTYGEEGLKDGHQSSHGDIFSHFF .::::.::..:.:. : .. :::::.: . ::.:: :::.::.: .:... . .... NP_001 KLHPDKNPNNPNAHGDFLKINRAYEVLKDEDLRKKYDKYGEKGLED-NQGGQYESWNYYR 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 GDFGFMFGGTPRQQDRNIPRGSDIIVDLEVTLEEVYAGNFVEVVRNKPVARQAPGKRKCN ::: .. : NP_001 YDFG-IYDDDPEIITLERREFDAAVNSGELWFVNFYSPGCSHCHDLAPTWRDFAKEVDGL 120 130 140 150 160 170 >>NP_061854 (OMIM: 607987) dnaJ homolog subfamily C memb (793 aa) initn: 291 init1: 291 opt: 337 Z-score: 395.0 bits: 82.8 E(85289): 2.9e-15 Smith-Waterman score: 337; 42.5% identity (78.8% similar) in 113 aa overlap (9-121:19-129) 10 20 30 40 50 pF1KB6 MAPQNLSTFCLLLLYLIGAVIAGRDFYKILGVPRSASIKDIKKAYRKLAL .:.:..:. : . .:::..::: ..:: ..:..:..:::: NP_061 MGVWLNKDDYIRDLKRIILCFLIVYMAILVGTDQDFYSLLGVSKTASSREIRQAFKKLAL 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 QLHPDRNPDDPQAQEKFQDLGAAYEVLSDSEKRKQYDTYGEEGLKDGHQSSHGDIFSHFF .::::.::..:.:. : .. :::::.: . ::.:: :::.::.: .:... . .... NP_061 KLHPDKNPNNPNAHGDFLKINRAYEVLKDEDLRKKYDKYGEKGLED-NQGGQYESWNYYR 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 GDFGFMFGGTPRQQDRNIPRGSDIIVDLEVTLEEVYAGNFVEVVRNKPVARQAPGKRKCN ::: .. : NP_061 YDFG-IYDDDPEIITLERREFDAAVNSGELWFVNFYSPGCSHCHDLAPTWRDFAKEVDGL 120 130 140 150 160 170 >>NP_001128582 (OMIM: 608382) dnaJ homolog subfamily A m (453 aa) initn: 347 init1: 300 opt: 329 Z-score: 389.2 bits: 80.9 E(85289): 6.1e-15 Smith-Waterman score: 434; 27.5% identity (56.9% similar) in 367 aa overlap (19-355:87-441) 10 20 30 40 pF1KB6 MAPQNLSTFCLLLLYLIGAVIAGRDFYKILGVPRSASIKDIKKAYRKL : .: .:.:.::::::.:: :.::::: .: NP_001 PRALLTLRPGVSLTGTKHNPFICTASFHTSAPLAKEDYYQILGVPRNASQKEIKKAYYQL 60 70 80 90 100 110 50 60 70 80 90 100 pF1KB6 ALQLHPDRNPDDPQAQEKFQDLGAAYEVLSDSEKRKQYDTYGEEGLKDGHQSS-HG---- : . ::: : :::.:.:::..:. ::::::: ::::::.:: :. : ..: :. NP_001 AKKYHPDTNKDDPKAKEKFSQLAEAYEVLSDEVKRKQYDAYGSAGFDPGASGSQHSYWKG 120 130 140 150 160 170 110 120 130 140 150 pF1KB6 -------DIFSHFFGDFGFM-FGGTPRQQDRNIPRGSDIIVDLEVT-LEEVYAGNFVEVV ..: ..::.:. :: :. .. . . ... .. :.... NP_001 GPTVDPEELFRKIFGEFSSSSFGDFQTVFDQPQEYFMELTFNQAAKGVNKEFTVNIMDTC 180 190 200 210 220 230 160 170 180 190 200 pF1KB6 RNKPVARQAPGKRKCNCR----QEMRTTQLGPGRFQMTQE-------VV---CDECPNVK . . :: . .:. . :.: . :: .. : . .. : : .. NP_001 ERCNGKGNEPGTKVQHCHYCGGSGMETINTGPFVMRSTCRRCGGRGSIIISPCVVCRGAG 240 250 260 270 280 290 210 220 230 240 250 pF1KB6 LVNEERTLEVEIEPGVRDG--MEYPFIGEGEPHVDGEPGDLRFRIKVVKHPIFERRGDDL ..... . . . ::.:: ...: .:. : . ::.. : :.:.: : :. NP_001 QAKQKKRVMIPVPAGVEDGQTVRMP-VGKREIFIT-------FRVQ--KSPVFRRDGADI 300 310 320 330 340 260 270 280 290 300 310 pF1KB6 YTNVTVSLVESLVGFEMDITHLDGHKVHISRDKITRPGAKLWKKGEGLPNFDNNNIKGSL .... .:....:.: : . .... :. :. :.:.: . :. :. NP_001 HSDLFISIAQALLGGTARAQGLY-ETINVTIPPGTQTDQKIRMGGKGIPRI-NSYGYGDH 350 360 370 380 390 400 320 330 340 350 pF1KB6 IITFDVDFPKEQLTEEAREGIKQLLKQGSVQKVYNGLQGY : . . ::. ... .. . .:. . ::. NP_001 YIHIKIRVPKRLTSRQQSLILSYAEDETDVEGTVNGVTLTSSGKRSTGN 410 420 430 440 450 >>NP_005138 (OMIM: 608382) dnaJ homolog subfamily A memb (480 aa) initn: 347 init1: 300 opt: 329 Z-score: 388.8 bits: 80.9 E(85289): 6.4e-15 Smith-Waterman score: 434; 27.5% identity (56.9% similar) in 367 aa overlap (19-355:87-441) 10 20 30 40 pF1KB6 MAPQNLSTFCLLLLYLIGAVIAGRDFYKILGVPRSASIKDIKKAYRKL : .: .:.:.::::::.:: :.::::: .: NP_005 PRALLTLRPGVSLTGTKHNPFICTASFHTSAPLAKEDYYQILGVPRNASQKEIKKAYYQL 60 70 80 90 100 110 50 60 70 80 90 100 pF1KB6 ALQLHPDRNPDDPQAQEKFQDLGAAYEVLSDSEKRKQYDTYGEEGLKDGHQSS-HG---- : . ::: : :::.:.:::..:. ::::::: ::::::.:: :. : ..: :. NP_005 AKKYHPDTNKDDPKAKEKFSQLAEAYEVLSDEVKRKQYDAYGSAGFDPGASGSQHSYWKG 120 130 140 150 160 170 110 120 130 140 150 pF1KB6 -------DIFSHFFGDFGFM-FGGTPRQQDRNIPRGSDIIVDLEVT-LEEVYAGNFVEVV ..: ..::.:. :: :. .. . . ... .. :.... NP_005 GPTVDPEELFRKIFGEFSSSSFGDFQTVFDQPQEYFMELTFNQAAKGVNKEFTVNIMDTC 180 190 200 210 220 230 160 170 180 190 200 pF1KB6 RNKPVARQAPGKRKCNCR----QEMRTTQLGPGRFQMTQE-------VV---CDECPNVK . . :: . .:. . :.: . :: .. : . .. : : .. NP_005 ERCNGKGNEPGTKVQHCHYCGGSGMETINTGPFVMRSTCRRCGGRGSIIISPCVVCRGAG 240 250 260 270 280 290 210 220 230 240 250 pF1KB6 LVNEERTLEVEIEPGVRDG--MEYPFIGEGEPHVDGEPGDLRFRIKVVKHPIFERRGDDL ..... . . . ::.:: ...: .:. : . ::.. : :.:.: : :. NP_005 QAKQKKRVMIPVPAGVEDGQTVRMP-VGKREIFIT-------FRVQ--KSPVFRRDGADI 300 310 320 330 340 260 270 280 290 300 310 pF1KB6 YTNVTVSLVESLVGFEMDITHLDGHKVHISRDKITRPGAKLWKKGEGLPNFDNNNIKGSL .... .:....:.: : . .... :. :. :.:.: . :. :. NP_005 HSDLFISIAQALLGGTARAQGLY-ETINVTIPPGTQTDQKIRMGGKGIPRI-NSYGYGDH 350 360 370 380 390 400 320 330 340 350 pF1KB6 IITFDVDFPKEQLTEEAREGIKQLLKQGSVQKVYNGLQGY : . . ::. ... .. . .:. . ::. NP_005 YIHIKIRVPKRLTSRQQSLILSYAEDETDVEGTVNGVTLTSSGGSTMDSSAGSKARREAG 410 420 430 440 450 460 NP_005 EDEEGFLSKLKKMFTS 470 480 >>XP_006722796 (OMIM: 604572) PREDICTED: dnaJ homolog su (240 aa) initn: 360 init1: 271 opt: 325 Z-score: 388.6 bits: 79.9 E(85289): 6.6e-15 Smith-Waterman score: 325; 27.3% identity (58.2% similar) in 249 aa overlap (105-343:1-238) 80 90 100 110 120 130 pF1KB6 EVLSDSEKRKQYDTYGEEGLKDGHQSSHGDIFSHFFGD---FGFMFGGTPRQQDRNIPRG .:..::: : .:: .:: .: XP_006 MFAEFFGGRNPFDTFFG------QRNGEEG 10 20 140 150 160 170 180 pF1KB6 SDIIVDLEVTLEEVYAGNFVEVVRNKPVARQAPGKRKCN--CRQEMRTT--QLGPG---R :: : . . :.:..: .. . : :...: . ...:.. .. : . XP_006 MDI--DDPFSGFPMGMGGFTNVNFGRSRSAQEPARKKQDPPVTHDLRVSLEEIYSGCTKK 30 40 50 60 70 80 190 200 210 220 230 240 pF1KB6 FQMTQEVVCDECPNVKLVNEERTLEVEIEPGVRDGMEYPFIGEGEPHVDGEPGDLRFRIK ...... . . ... ::.. : .:.. : ..: . : ::. .. :.:. : .: XP_006 MKISHKRLNPDGKSIR--NEDKILTIEVKKGWKEGTKITFPKEGDQTSNNIPADIVFVLK 90 100 110 120 130 140 250 260 270 280 290 300 pF1KB6 VVKHPIFERRGDDLYTNVTVSLVESLVGFEMDITHLDGHKVHISRDKITRPGAKLWKKGE : ::.: :.:. . .:: :.: : ... :::. . . . ::: . :: XP_006 DKPHNIFKRDGSDVIYPARISLREALCGCTVNVPTLDGRTIPVVFKDVIRPGMRRKVPGE 150 160 170 180 190 200 310 320 330 340 350 pF1KB6 GLPNFDNNNIKGSLIITFDVDFPKEQLTEEAREGIKQLLKQGSVQKVYNGLQGY ::: . . .:.::: :.: :: :.. . .: ..:.: XP_006 GLPLPKTPEKRGDLIIEFEVIFP-ERIPQTSRTVLEQVLPI 210 220 230 240 358 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 23:10:52 2016 done: Fri Nov 4 23:10:53 2016 Total Scan time: 5.550 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]