FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6497, 351 aa 1>>>pF1KB6497 351 - 351 aa - 351 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.7007+/-0.0013; mu= 3.3901+/- 0.074 mean_var=245.2471+/-58.175, 0's: 0 Z-trim(105.7): 719 B-trim: 0 in 0/51 Lambda= 0.081898 statistics sampled from 7728 (8548) to 7728 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.626), E-opt: 0.2 (0.263), width: 16 Scan time: 2.590 The best scores are: opt bits E(32554) CCDS6625.1 PRKACG gene_id:5568|Hs108|chr9 ( 351) 2359 292.7 3.2e-79 CCDS12304.1 PRKACA gene_id:5566|Hs108|chr19 ( 351) 2021 252.7 3.3e-67 CCDS12305.1 PRKACA gene_id:5566|Hs108|chr19 ( 343) 1974 247.2 1.5e-65 CCDS691.1 PRKACB gene_id:5567|Hs108|chr1 ( 351) 1916 240.3 1.8e-63 CCDS55610.1 PRKACB gene_id:5567|Hs108|chr1 ( 355) 1888 237.0 1.8e-62 CCDS72815.1 PRKACB gene_id:5567|Hs108|chr1 ( 357) 1886 236.8 2.1e-62 CCDS55609.1 PRKACB gene_id:5567|Hs108|chr1 ( 358) 1886 236.8 2.1e-62 CCDS693.1 PRKACB gene_id:5567|Hs108|chr1 ( 398) 1882 236.4 3.2e-62 CCDS72813.1 PRKACB gene_id:5567|Hs108|chr1 ( 339) 1875 235.5 5.1e-62 CCDS72816.1 PRKACB gene_id:5567|Hs108|chr1 ( 338) 1789 225.3 5.8e-59 CCDS55611.1 PRKACB gene_id:5567|Hs108|chr1 ( 321) 1433 183.2 2.6e-46 CCDS692.1 PRKACB gene_id:5567|Hs108|chr1 ( 257) 1376 176.4 2.4e-44 CCDS72814.1 PRKACB gene_id:5567|Hs108|chr1 ( 264) 1350 173.3 2.1e-43 CCDS72812.1 PRKACB gene_id:5567|Hs108|chr1 ( 245) 1335 171.5 6.7e-43 CCDS14125.1 PRKX gene_id:5613|Hs108|chrX ( 358) 1149 149.7 3.5e-36 CCDS44399.1 PRKG1 gene_id:5592|Hs108|chr10 ( 671) 913 122.2 1.3e-27 CCDS7244.1 PRKG1 gene_id:5592|Hs108|chr10 ( 686) 913 122.2 1.3e-27 CCDS75150.1 PRKG2 gene_id:5593|Hs108|chr4 ( 342) 907 121.1 1.4e-27 CCDS5170.1 SGK1 gene_id:6446|Hs108|chr6 ( 431) 906 121.1 1.7e-27 CCDS47478.1 SGK1 gene_id:6446|Hs108|chr6 ( 445) 906 121.1 1.8e-27 CCDS47477.1 SGK1 gene_id:6446|Hs108|chr6 ( 459) 906 121.1 1.8e-27 CCDS47476.1 SGK1 gene_id:6446|Hs108|chr6 ( 526) 906 121.2 2e-27 CCDS3589.1 PRKG2 gene_id:5593|Hs108|chr4 ( 762) 908 121.6 2.1e-27 CCDS13321.1 SGK2 gene_id:10110|Hs108|chr20 ( 367) 896 119.8 3.6e-27 CCDS13320.1 SGK2 gene_id:10110|Hs108|chr20 ( 427) 896 119.9 3.9e-27 CCDS31076.1 AKT3 gene_id:10000|Hs108|chr1 ( 465) 872 117.1 2.9e-26 CCDS9994.1 AKT1 gene_id:207|Hs108|chr14 ( 480) 861 115.8 7.4e-26 CCDS31077.1 AKT3 gene_id:10000|Hs108|chr1 ( 479) 858 115.5 9.4e-26 CCDS12552.1 AKT2 gene_id:208|Hs108|chr19 ( 481) 854 115.0 1.3e-25 CCDS64005.1 PRKG2 gene_id:5593|Hs108|chr4 ( 733) 847 114.4 3e-25 CCDS6195.1 SGK3 gene_id:23678|Hs108|chr8 ( 496) 835 112.8 6.3e-25 CCDS81350.1 PKN2 gene_id:5586|Hs108|chr1 ( 936) 816 110.9 4.5e-24 CCDS714.1 PKN2 gene_id:5586|Hs108|chr1 ( 984) 816 110.9 4.6e-24 CCDS41677.1 RPS6KB2 gene_id:6199|Hs108|chr11 ( 482) 804 109.1 7.9e-24 CCDS62271.1 RPS6KB1 gene_id:6198|Hs108|chr17 ( 451) 794 107.9 1.7e-23 CCDS62273.1 RPS6KB1 gene_id:6198|Hs108|chr17 ( 472) 794 107.9 1.8e-23 CCDS11621.1 RPS6KB1 gene_id:6198|Hs108|chr17 ( 525) 794 108.0 1.9e-23 CCDS9752.1 PRKCH gene_id:5583|Hs108|chr14 ( 683) 793 108.0 2.4e-23 CCDS42513.1 PKN1 gene_id:5585|Hs108|chr19 ( 942) 790 107.8 3.8e-23 CCDS42514.1 PKN1 gene_id:5585|Hs108|chr19 ( 948) 790 107.8 3.8e-23 CCDS6908.1 PKN3 gene_id:29941|Hs108|chr9 ( 889) 785 107.2 5.5e-23 CCDS5294.1 RPS6KA2 gene_id:6196|Hs108|chr6 ( 733) 781 106.6 6.8e-23 CCDS34570.1 RPS6KA2 gene_id:6196|Hs108|chr6 ( 741) 781 106.6 6.8e-23 CCDS83148.1 RPS6KA2 gene_id:6196|Hs108|chr6 ( 758) 781 106.6 6.9e-23 CCDS11664.1 PRKCA gene_id:5578|Hs108|chr17 ( 672) 776 106.0 9.6e-23 CCDS1824.1 PRKCE gene_id:5581|Hs108|chr2 ( 737) 773 105.7 1.3e-22 CCDS10618.1 PRKCB gene_id:5579|Hs108|chr16 ( 671) 762 104.3 3e-22 CCDS81286.1 RPS6KA1 gene_id:6195|Hs108|chr1 ( 719) 761 104.2 3.4e-22 CCDS284.1 RPS6KA1 gene_id:6195|Hs108|chr1 ( 735) 761 104.2 3.5e-22 CCDS30649.1 RPS6KA1 gene_id:6195|Hs108|chr1 ( 744) 761 104.3 3.5e-22 >>CCDS6625.1 PRKACG gene_id:5568|Hs108|chr9 (351 aa) initn: 2359 init1: 2359 opt: 2359 Z-score: 1535.8 bits: 292.7 E(32554): 3.2e-79 Smith-Waterman score: 2359; 100.0% identity (100.0% similar) in 351 aa overlap (1-351:1-351) 10 20 30 40 50 60 pF1KB6 MGNAPAKKDTEQEESVNEFLAKARGDFLYRWGNPAQNTASSDQFERLRTLGMGSFGRVML :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 MGNAPAKKDTEQEESVNEFLAKARGDFLYRWGNPAQNTASSDQFERLRTLGMGSFGRVML 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 VRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAIDFPFLVKLQFSFKDNSYLYLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 VRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAIDFPFLVKLQFSFKDNSYLYLV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 MEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLHSLDLIHRDLKPENLLIDQQGY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 MEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLHSLDLIHRDLKPENLLIDQQGY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 LQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAVGFPPFY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 LQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAVGFPPFY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 ADQPIQIYEKIVSGRVRFPSKLSSDLKHLLRSLLQVDLTKRFGNLRNGVGDIKNHKWFAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 ADQPIQIYEKIVSGRVRFPSKLSSDLKHLLRSLLQVDLTKRFGNLRNGVGDIKNHKWFAT 250 260 270 280 290 300 310 320 330 340 350 pF1KB6 TSWIAIYEKKVEAPFIPKYTGPGDASNFDDYEEEELRISINEKCAKEFSEF ::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 TSWIAIYEKKVEAPFIPKYTGPGDASNFDDYEEEELRISINEKCAKEFSEF 310 320 330 340 350 >>CCDS12304.1 PRKACA gene_id:5566|Hs108|chr19 (351 aa) initn: 2021 init1: 2021 opt: 2021 Z-score: 1320.0 bits: 252.7 E(32554): 3.3e-67 Smith-Waterman score: 2021; 82.9% identity (95.2% similar) in 351 aa overlap (1-351:1-351) 10 20 30 40 50 60 pF1KB6 MGNAPAKKDTEQEESVNEFLAKARGDFLYRWGNPAQNTASSDQFERLRTLGMGSFGRVML :::: : : ..:::.::::::. ::: .: .:::::: :::::..::: :::::::: CCDS12 MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVML 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 VRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAIDFPFLVKLQFSFKDNSYLYLV :.:.:::.:::::::.::::::.::.:: :::::::::..:::::::.::::::: ::.: CCDS12 VKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 MEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLHSLDLIHRDLKPENLLIDQQGY :::::::::::.:.:.:::::::: :::::.::. .::::::::.::::::::::::::: CCDS12 MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 LQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAVGFPPFY .::::::::::::::::::::::::::::::::::::::::::::::::::::.:.:::. CCDS12 IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 ADQPIQIYEKIVSGRVRFPSKLSSDLKHLLRSLLQVDLTKRFGNLRNGVGDIKNHKWFAT ::::::::::::::.:::::..::::: :::.:::::::::::::.:::.:::::::::: CCDS12 ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFAT 250 260 270 280 290 300 310 320 330 340 350 pF1KB6 TSWIAIYEKKVEAPFIPKYTGPGDASNFDDYEEEELRISINEKCAKEFSEF :.:::::..:::::::::. ::::.::::::::::.:.::::::.:::::: CCDS12 TDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 310 320 330 340 350 >>CCDS12305.1 PRKACA gene_id:5566|Hs108|chr19 (343 aa) initn: 1974 init1: 1974 opt: 1974 Z-score: 1290.1 bits: 247.2 E(32554): 1.5e-65 Smith-Waterman score: 1974; 84.2% identity (96.4% similar) in 336 aa overlap (16-351:8-343) 10 20 30 40 50 60 pF1KB6 MGNAPAKKDTEQEESVNEFLAKARGDFLYRWGNPAQNTASSDQFERLRTLGMGSFGRVML :.::::::. ::: .: .:::::: :::::..::: :::::::: CCDS12 MASNSSDVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVML 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 VRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAIDFPFLVKLQFSFKDNSYLYLV :.:.:::.:::::::.::::::.::.:: :::::::::..:::::::.::::::: ::.: CCDS12 VKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMV 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 MEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLHSLDLIHRDLKPENLLIDQQGY :::::::::::.:.:.:::::::: :::::.::. .::::::::.::::::::::::::: CCDS12 MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGY 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB6 LQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAVGFPPFY .::::::::::::::::::::::::::::::::::::::::::::::::::::.:.:::. CCDS12 IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB6 ADQPIQIYEKIVSGRVRFPSKLSSDLKHLLRSLLQVDLTKRFGNLRNGVGDIKNHKWFAT ::::::::::::::.:::::..::::: :::.:::::::::::::.:::.:::::::::: CCDS12 ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFAT 240 250 260 270 280 290 310 320 330 340 350 pF1KB6 TSWIAIYEKKVEAPFIPKYTGPGDASNFDDYEEEELRISINEKCAKEFSEF :.:::::..:::::::::. ::::.::::::::::.:.::::::.:::::: CCDS12 TDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF 300 310 320 330 340 >>CCDS691.1 PRKACB gene_id:5567|Hs108|chr1 (351 aa) initn: 1916 init1: 1916 opt: 1916 Z-score: 1252.9 bits: 240.3 E(32554): 1.8e-63 Smith-Waterman score: 1916; 78.6% identity (93.7% similar) in 351 aa overlap (1-351:1-351) 10 20 30 40 50 60 pF1KB6 MGNAPAKKDTEQEESVNEFLAKARGDFLYRWGNPAQNTASSDQFERLRTLGMGSFGRVML :::: . : . :::.::::::. ::: .: ::.::.:. ..::: .::: :::::::: CCDS69 MGNAATAKKGSEVESVKEFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVML 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 VRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAIDFPFLVKLQFSFKDNSYLYLV :.:. : .::::::.::::::.::.:: :::::::::..:::::.:...::::: ::.: CCDS69 VKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 MEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLHSLDLIHRDLKPENLLIDQQGY :::::::::::.:.:.:::::::: :::::.::. .::::::::.:::::::::::.::: CCDS69 MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 LQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAVGFPPFY .::::::::::::::::::::::::::::::::::::::::::::::::::::.:.:::. CCDS69 IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 ADQPIQIYEKIVSGRVRFPSKLSSDLKHLLRSLLQVDLTKRFGNLRNGVGDIKNHKWFAT ::::::::::::::.:::::..::::: :::.:::::::::::::.:::.:::.:::::: CCDS69 ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFAT 250 260 270 280 290 300 310 320 330 340 350 pF1KB6 TSWIAIYEKKVEAPFIPKYTGPGDASNFDDYEEEELRISINEKCAKEFSEF :.:::::..:::::::::. : ::.:::::::::..:.::.:::::::.:: CCDS69 TDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEEDIRVSITEKCAKEFGEF 310 320 330 340 350 >>CCDS55610.1 PRKACB gene_id:5567|Hs108|chr1 (355 aa) initn: 1887 init1: 1887 opt: 1888 Z-score: 1235.0 bits: 237.0 E(32554): 1.8e-62 Smith-Waterman score: 1888; 77.9% identity (94.0% similar) in 349 aa overlap (3-351:7-355) 10 20 30 40 50 pF1KB6 MGNAPAKKDTEQEESVNEFLAKARGDFLYRWGNPAQNTASSDQFERLRTLGMGSFG .. :. . .: ::.::::::. ::: .: ::.::.:. ..::: .::: :::: CCDS55 MGLSRKSSDASACSSSEISVKEFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFG 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 RVMLVRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAIDFPFLVKLQFSFKDNSY :::::.:. : .::::::.::::::.::.:: :::::::::..:::::.:...::::: CCDS55 RVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSN 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 LYLVMEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLHSLDLIHRDLKPENLLID ::.::::::::::::.:.:.:::::::: :::::.::. .::::::::.::::::::::: CCDS55 LYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLID 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB6 QQGYLQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAVGF .:::.::::::::::::::::::::::::::::::::::::::::::::::::::::.:. CCDS55 HQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGY 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB6 PPFYADQPIQIYEKIVSGRVRFPSKLSSDLKHLLRSLLQVDLTKRFGNLRNGVGDIKNHK :::.::::::::::::::.:::::..::::: :::.:::::::::::::.:::.:::.:: CCDS55 PPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHK 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB6 WFATTSWIAIYEKKVEAPFIPKYTGPGDASNFDDYEEEELRISINEKCAKEFSEF :::::.:::::..:::::::::. : ::.:::::::::..:.::.:::::::.:: CCDS55 WFATTDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEEDIRVSITEKCAKEFGEF 310 320 330 340 350 >>CCDS72815.1 PRKACB gene_id:5567|Hs108|chr1 (357 aa) initn: 1879 init1: 1879 opt: 1886 Z-score: 1233.7 bits: 236.8 E(32554): 2.1e-62 Smith-Waterman score: 1886; 78.0% identity (94.0% similar) in 350 aa overlap (3-351:8-357) 10 20 30 40 50 pF1KB6 MGNAPAKKDTEQEES-VNEFLAKARGDFLYRWGNPAQNTASSDQFERLRTLGMGS .: : ...: .: :.::::::. ::: .: ::.::.:. ..::: .::: :: CCDS72 MSARKSSDASACSSSEISDSFVKEFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGS 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 FGRVMLVRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAIDFPFLVKLQFSFKDN :::::::.:. : .::::::.::::::.::.:: :::::::::..:::::.:...:::: CCDS72 FGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDN 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 SYLYLVMEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLHSLDLIHRDLKPENLL : ::.::::::::::::.:.:.:::::::: :::::.::. .::::::::.::::::::: CCDS72 SNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLL 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB6 IDQQGYLQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAV ::.:::.::::::::::::::::::::::::::::::::::::::::::::::::::::. CCDS72 IDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAA 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB6 GFPPFYADQPIQIYEKIVSGRVRFPSKLSSDLKHLLRSLLQVDLTKRFGNLRNGVGDIKN :.:::.::::::::::::::.:::::..::::: :::.:::::::::::::.:::.:::. CCDS72 GYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKT 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB6 HKWFATTSWIAIYEKKVEAPFIPKYTGPGDASNFDDYEEEELRISINEKCAKEFSEF :::::::.:::::..:::::::::. : ::.:::::::::..:.::.:::::::.:: CCDS72 HKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEEDIRVSITEKCAKEFGEF 310 320 330 340 350 >>CCDS55609.1 PRKACB gene_id:5567|Hs108|chr1 (358 aa) initn: 1879 init1: 1879 opt: 1886 Z-score: 1233.7 bits: 236.8 E(32554): 2.1e-62 Smith-Waterman score: 1886; 78.0% identity (94.0% similar) in 350 aa overlap (3-351:9-358) 10 20 30 40 50 pF1KB6 MGNAPAKKDTEQEES-VNEFLAKARGDFLYRWGNPAQNTASSDQFERLRTLGMG .: : ...: .: :.::::::. ::: .: ::.::.:. ..::: .::: : CCDS55 MGLSRKSSDASACSSSEISDSFVKEFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTG 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 SFGRVMLVRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAIDFPFLVKLQFSFKD ::::::::.:. : .::::::.::::::.::.:: :::::::::..:::::.:...::: CCDS55 SFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKD 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 NSYLYLVMEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLHSLDLIHRDLKPENL :: ::.::::::::::::.:.:.:::::::: :::::.::. .::::::::.:::::::: CCDS55 NSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENL 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB6 LIDQQGYLQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMA :::.:::.:::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS55 LIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMA 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB6 VGFPPFYADQPIQIYEKIVSGRVRFPSKLSSDLKHLLRSLLQVDLTKRFGNLRNGVGDIK .:.:::.::::::::::::::.:::::..::::: :::.:::::::::::::.:::.::: CCDS55 AGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIK 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB6 NHKWFATTSWIAIYEKKVEAPFIPKYTGPGDASNFDDYEEEELRISINEKCAKEFSEF .:::::::.:::::..:::::::::. : ::.:::::::::..:.::.:::::::.:: CCDS55 THKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEEDIRVSITEKCAKEFGEF 310 320 330 340 350 >>CCDS693.1 PRKACB gene_id:5567|Hs108|chr1 (398 aa) initn: 1882 init1: 1882 opt: 1882 Z-score: 1230.6 bits: 236.4 E(32554): 3.2e-62 Smith-Waterman score: 1882; 79.4% identity (95.3% similar) in 339 aa overlap (13-351:60-398) 10 20 30 40 pF1KB6 MGNAPAKKDTEQEESVNEFLAKARGDFLYRWGNPAQNTASSD ..:..::::::. ::: .: ::.::.:. . CCDS69 FHRHSKGTAHDQKTALENDSLHFSEHTALWDRSMKEFLAKAKEDFLKKWENPTQNNAGLE 30 40 50 60 70 80 50 60 70 80 90 100 pF1KB6 QFERLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAIDFP .::: .::: :::::::::.:. : .::::::.::::::.::.:: :::::::::..:: CCDS69 DFERKKTLGTGSFGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFP 90 100 110 120 130 140 110 120 130 140 150 160 pF1KB6 FLVKLQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLHSLD :::.:...::::: ::.::::::::::::.:.:.:::::::: :::::.::. .:::::: CCDS69 FLVRLEYAFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLD 150 160 170 180 190 200 170 180 190 200 210 220 pF1KB6 LIHRDLKPENLLIDQQGYLQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDW ::.:::::::::::.:::.::::::::::::::::::::::::::::::::::::::::: CCDS69 LIYRDLKPENLLIDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDW 210 220 230 240 250 260 230 240 250 260 270 280 pF1KB6 WALGVLIYEMAVGFPPFYADQPIQIYEKIVSGRVRFPSKLSSDLKHLLRSLLQVDLTKRF :::::::::::.:.:::.::::::::::::::.:::::..::::: :::.:::::::::: CCDS69 WALGVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRF 270 280 290 300 310 320 290 300 310 320 330 340 pF1KB6 GNLRNGVGDIKNHKWFATTSWIAIYEKKVEAPFIPKYTGPGDASNFDDYEEEELRISINE :::.:::.:::.:::::::.:::::..:::::::::. : ::.:::::::::..:.::.: CCDS69 GNLKNGVSDIKTHKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEEDIRVSITE 330 340 350 360 370 380 350 pF1KB6 KCAKEFSEF ::::::.:: CCDS69 KCAKEFGEF 390 >>CCDS72813.1 PRKACB gene_id:5567|Hs108|chr1 (339 aa) initn: 1875 init1: 1875 opt: 1875 Z-score: 1226.9 bits: 235.5 E(32554): 5.1e-62 Smith-Waterman score: 1875; 79.8% identity (95.2% similar) in 336 aa overlap (16-351:4-339) 10 20 30 40 50 60 pF1KB6 MGNAPAKKDTEQEESVNEFLAKARGDFLYRWGNPAQNTASSDQFERLRTLGMGSFGRVML ..::::::. ::: .: ::.::.:. ..::: .::: :::::::: CCDS72 MGLLKEFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVML 10 20 30 40 70 80 90 100 110 120 pF1KB6 VRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAIDFPFLVKLQFSFKDNSYLYLV :.:. : .::::::.::::::.::.:: :::::::::..:::::.:...::::: ::.: CCDS72 VKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMV 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB6 MEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLHSLDLIHRDLKPENLLIDQQGY :::::::::::.:.:.:::::::: :::::.::. .::::::::.:::::::::::.::: CCDS72 MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGY 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB6 LQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAVGFPPFY .::::::::::::::::::::::::::::::::::::::::::::::::::::.:.:::. CCDS72 IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB6 ADQPIQIYEKIVSGRVRFPSKLSSDLKHLLRSLLQVDLTKRFGNLRNGVGDIKNHKWFAT ::::::::::::::.:::::..::::: :::.:::::::::::::.:::.:::.:::::: CCDS72 ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFAT 230 240 250 260 270 280 310 320 330 340 350 pF1KB6 TSWIAIYEKKVEAPFIPKYTGPGDASNFDDYEEEELRISINEKCAKEFSEF :.:::::..:::::::::. : ::.:::::::::..:.::.:::::::.:: CCDS72 TDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEEDIRVSITEKCAKEFGEF 290 300 310 320 330 >>CCDS72816.1 PRKACB gene_id:5567|Hs108|chr1 (338 aa) initn: 1789 init1: 1789 opt: 1789 Z-score: 1172.0 bits: 225.3 E(32554): 5.8e-59 Smith-Waterman score: 1789; 80.8% identity (95.9% similar) in 317 aa overlap (35-351:22-338) 10 20 30 40 50 60 pF1KB6 PAKKDTEQEESVNEFLAKARGDFLYRWGNPAQNTASSDQFERLRTLGMGSFGRVMLVRHQ .::.:. ..::: .::: :::::::::.:. CCDS72 MLLLSSSISLYKDRNEARLISSQNNAGLEDFERKKTLGTGSFGRVMLVKHK 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 ETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAIDFPFLVKLQFSFKDNSYLYLVMEYV : .::::::.::::::.::.:: :::::::::..:::::.:...::::: ::.::::: CCDS72 ATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMVMEYV 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 PGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLHSLDLIHRDLKPENLLIDQQGYLQVT :::::::.:.:.:::::::: :::::.::. .::::::::.:::::::::::.:::.::: CCDS72 PGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGYIQVT 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB6 DFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAVGFPPFYADQP :::::::::::::::::::::::::::::::::::::::::::::::::.:.:::.:::: CCDS72 DFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFFADQP 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB6 IQIYEKIVSGRVRFPSKLSSDLKHLLRSLLQVDLTKRFGNLRNGVGDIKNHKWFATTSWI ::::::::::.:::::..::::: :::.:::::::::::::.:::.:::.:::::::.:: CCDS72 IQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFATTDWI 240 250 260 270 280 290 310 320 330 340 350 pF1KB6 AIYEKKVEAPFIPKYTGPGDASNFDDYEEEELRISINEKCAKEFSEF :::..:::::::::. : ::.:::::::::..:.::.:::::::.:: CCDS72 AIYQRKVEAPFIPKFRGSGDTSNFDDYEEEDIRVSITEKCAKEFGEF 300 310 320 330 351 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 00:59:29 2016 done: Sat Nov 5 00:59:30 2016 Total Scan time: 2.590 Total Display time: 0.050 Function used was FASTA [36.3.4 Apr, 2011]