Result of FASTA (omim) for
pF1KB6497
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6497, 351 aa
1>>>pF1KB6497 351 - 351 aa - 351 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.1952+/-0.000628; mu= 2.4647+/- 0.037
mean_var=648.1595+/-151.160, 0's: 0 Z-trim(113.2): 1992 B-trim: 0 in 0/50
Lambda= 0.050377
statistics sampled from 19819 (22425) to 19819 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.615), E-opt: 0.2 (0.263), width: 16
Scan time: 6.910
The best scores are: opt bits E(85289)
NP_002723 (OMIM: 176893,616176) cAMP-dependent pro ( 351) 2359 187.5 3.9e-47
NP_002721 (OMIM: 601639,615830) cAMP-dependent pro ( 351) 2021 162.9 9.7e-40
NP_997401 (OMIM: 601639,615830) cAMP-dependent pro ( 343) 1974 159.4 1e-38
NP_001291278 (OMIM: 601639,615830) cAMP-dependent ( 427) 1974 159.6 1.1e-38
NP_002722 (OMIM: 176892) cAMP-dependent protein ki ( 351) 1916 155.3 1.9e-37
XP_006710821 (OMIM: 176892) PREDICTED: cAMP-depend ( 354) 1888 153.2 7.9e-37
NP_001229788 (OMIM: 176892) cAMP-dependent protein ( 355) 1888 153.2 7.9e-37
XP_005271075 (OMIM: 176892) PREDICTED: cAMP-depend ( 346) 1887 153.1 8.3e-37
XP_005271074 (OMIM: 176892) PREDICTED: cAMP-depend ( 347) 1887 153.1 8.3e-37
NP_001229789 (OMIM: 176892) cAMP-dependent protein ( 357) 1886 153.1 8.8e-37
NP_001229786 (OMIM: 176892) cAMP-dependent protein ( 358) 1886 153.1 8.8e-37
XP_005271076 (OMIM: 176892) PREDICTED: cAMP-depend ( 338) 1884 152.9 9.5e-37
NP_891993 (OMIM: 176892) cAMP-dependent protein ki ( 398) 1882 152.9 1.1e-36
XP_005271073 (OMIM: 176892) PREDICTED: cAMP-depend ( 349) 1880 152.6 1.2e-36
XP_005271072 (OMIM: 176892) PREDICTED: cAMP-depend ( 350) 1879 152.6 1.2e-36
NP_001229787 (OMIM: 176892) cAMP-dependent protein ( 339) 1875 152.2 1.5e-36
NP_001229791 (OMIM: 176892) cAMP-dependent protein ( 338) 1789 146.0 1.1e-34
XP_016882437 (OMIM: 601639,615830) PREDICTED: cAMP ( 296) 1464 122.3 1.4e-27
NP_001229790 (OMIM: 176892) cAMP-dependent protein ( 321) 1433 120.1 6.9e-27
XP_016857202 (OMIM: 176892) PREDICTED: cAMP-depend ( 258) 1380 116.0 9.1e-26
NP_997461 (OMIM: 176892) cAMP-dependent protein ki ( 257) 1376 115.7 1.1e-25
XP_016857199 (OMIM: 176892) PREDICTED: cAMP-depend ( 261) 1352 114.0 3.7e-25
XP_016857198 (OMIM: 176892) PREDICTED: cAMP-depend ( 262) 1352 114.0 3.7e-25
NP_001287844 (OMIM: 176892) cAMP-dependent protein ( 264) 1350 113.9 4.1e-25
XP_016857195 (OMIM: 176892) PREDICTED: cAMP-depend ( 265) 1350 113.9 4.2e-25
XP_016857208 (OMIM: 176892) PREDICTED: cAMP-depend ( 245) 1348 113.7 4.4e-25
XP_016857201 (OMIM: 176892) PREDICTED: cAMP-depend ( 260) 1348 113.7 4.6e-25
XP_016857200 (OMIM: 176892) PREDICTED: cAMP-depend ( 261) 1348 113.7 4.6e-25
XP_016857206 (OMIM: 176892) PREDICTED: cAMP-depend ( 252) 1347 113.6 4.7e-25
XP_016857205 (OMIM: 176892) PREDICTED: cAMP-depend ( 253) 1347 113.6 4.7e-25
XP_016857197 (OMIM: 176892) PREDICTED: cAMP-depend ( 263) 1346 113.6 5.1e-25
XP_016857196 (OMIM: 176892) PREDICTED: cAMP-depend ( 264) 1346 113.6 5.1e-25
XP_005271077 (OMIM: 176892) PREDICTED: cAMP-depend ( 305) 1346 113.7 5.4e-25
XP_016857209 (OMIM: 176892) PREDICTED: cAMP-depend ( 244) 1344 113.4 5.4e-25
XP_016857203 (OMIM: 176892) PREDICTED: cAMP-depend ( 256) 1344 113.4 5.5e-25
NP_001287845 (OMIM: 176892) cAMP-dependent protein ( 304) 1342 113.4 6.6e-25
XP_016857204 (OMIM: 176892) PREDICTED: cAMP-depend ( 255) 1340 113.1 6.8e-25
XP_016857207 (OMIM: 176892) PREDICTED: cAMP-depend ( 246) 1339 113.0 7e-25
NP_001287846 (OMIM: 176892) cAMP-dependent protein ( 245) 1335 112.7 8.6e-25
NP_005035 (OMIM: 300083) cAMP-dependent protein ki ( 358) 1149 99.5 1.2e-20
XP_016871902 (OMIM: 176894,615436) PREDICTED: cGMP ( 585) 913 82.8 2.1e-15
XP_016871901 (OMIM: 176894,615436) PREDICTED: cGMP ( 591) 913 82.8 2.1e-15
NP_001091982 (OMIM: 176894,615436) cGMP-dependent ( 671) 913 82.9 2.2e-15
NP_006249 (OMIM: 176894,615436) cGMP-dependent pro ( 686) 913 82.9 2.2e-15
NP_001269410 (OMIM: 601591) cGMP-dependent protein ( 342) 907 81.9 2.3e-15
NP_001269409 (OMIM: 601591) cGMP-dependent protein ( 342) 907 81.9 2.3e-15
NP_005618 (OMIM: 602958) serine/threonine-protein ( 431) 906 82.0 2.6e-15
NP_001137150 (OMIM: 602958) serine/threonine-prote ( 445) 906 82.0 2.7e-15
NP_001137149 (OMIM: 602958) serine/threonine-prote ( 459) 906 82.1 2.7e-15
XP_011534373 (OMIM: 602958) PREDICTED: serine/thre ( 526) 906 82.2 2.9e-15
>>NP_002723 (OMIM: 176893,616176) cAMP-dependent protein (351 aa)
initn: 2359 init1: 2359 opt: 2359 Z-score: 967.2 bits: 187.5 E(85289): 3.9e-47
Smith-Waterman score: 2359; 100.0% identity (100.0% similar) in 351 aa overlap (1-351:1-351)
10 20 30 40 50 60
pF1KB6 MGNAPAKKDTEQEESVNEFLAKARGDFLYRWGNPAQNTASSDQFERLRTLGMGSFGRVML
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MGNAPAKKDTEQEESVNEFLAKARGDFLYRWGNPAQNTASSDQFERLRTLGMGSFGRVML
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 VRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAIDFPFLVKLQFSFKDNSYLYLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 VRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAIDFPFLVKLQFSFKDNSYLYLV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 MEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLHSLDLIHRDLKPENLLIDQQGY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 MEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLHSLDLIHRDLKPENLLIDQQGY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 LQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAVGFPPFY
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 LQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAVGFPPFY
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 ADQPIQIYEKIVSGRVRFPSKLSSDLKHLLRSLLQVDLTKRFGNLRNGVGDIKNHKWFAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 ADQPIQIYEKIVSGRVRFPSKLSSDLKHLLRSLLQVDLTKRFGNLRNGVGDIKNHKWFAT
250 260 270 280 290 300
310 320 330 340 350
pF1KB6 TSWIAIYEKKVEAPFIPKYTGPGDASNFDDYEEEELRISINEKCAKEFSEF
:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_002 TSWIAIYEKKVEAPFIPKYTGPGDASNFDDYEEEELRISINEKCAKEFSEF
310 320 330 340 350
>>NP_002721 (OMIM: 601639,615830) cAMP-dependent protein (351 aa)
initn: 2021 init1: 2021 opt: 2021 Z-score: 834.4 bits: 162.9 E(85289): 9.7e-40
Smith-Waterman score: 2021; 82.9% identity (95.2% similar) in 351 aa overlap (1-351:1-351)
10 20 30 40 50 60
pF1KB6 MGNAPAKKDTEQEESVNEFLAKARGDFLYRWGNPAQNTASSDQFERLRTLGMGSFGRVML
:::: : : ..:::.::::::. ::: .: .:::::: :::::..::: ::::::::
NP_002 MGNAAAAKKGSEQESVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVML
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 VRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAIDFPFLVKLQFSFKDNSYLYLV
:.:.:::.:::::::.::::::.::.:: :::::::::..:::::::.::::::: ::.:
NP_002 VKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 MEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLHSLDLIHRDLKPENLLIDQQGY
:::::::::::.:.:.:::::::: :::::.::. .::::::::.:::::::::::::::
NP_002 MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 LQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAVGFPPFY
.::::::::::::::::::::::::::::::::::::::::::::::::::::.:.:::.
NP_002 IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 ADQPIQIYEKIVSGRVRFPSKLSSDLKHLLRSLLQVDLTKRFGNLRNGVGDIKNHKWFAT
::::::::::::::.:::::..::::: :::.:::::::::::::.:::.::::::::::
NP_002 ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFAT
250 260 270 280 290 300
310 320 330 340 350
pF1KB6 TSWIAIYEKKVEAPFIPKYTGPGDASNFDDYEEEELRISINEKCAKEFSEF
:.:::::..:::::::::. ::::.::::::::::.:.::::::.::::::
NP_002 TDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF
310 320 330 340 350
>>NP_997401 (OMIM: 601639,615830) cAMP-dependent protein (343 aa)
initn: 1974 init1: 1974 opt: 1974 Z-score: 816.0 bits: 159.4 E(85289): 1e-38
Smith-Waterman score: 1974; 84.2% identity (96.4% similar) in 336 aa overlap (16-351:8-343)
10 20 30 40 50 60
pF1KB6 MGNAPAKKDTEQEESVNEFLAKARGDFLYRWGNPAQNTASSDQFERLRTLGMGSFGRVML
:.::::::. ::: .: .:::::: :::::..::: ::::::::
NP_997 MASNSSDVKEFLAKAKEDFLKKWESPAQNTAHLDQFERIKTLGTGSFGRVML
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 VRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAIDFPFLVKLQFSFKDNSYLYLV
:.:.:::.:::::::.::::::.::.:: :::::::::..:::::::.::::::: ::.:
NP_997 VKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVKLEFSFKDNSNLYMV
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB6 MEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLHSLDLIHRDLKPENLLIDQQGY
:::::::::::.:.:.:::::::: :::::.::. .::::::::.:::::::::::::::
NP_997 MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDQQGY
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB6 LQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAVGFPPFY
.::::::::::::::::::::::::::::::::::::::::::::::::::::.:.:::.
NP_997 IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB6 ADQPIQIYEKIVSGRVRFPSKLSSDLKHLLRSLLQVDLTKRFGNLRNGVGDIKNHKWFAT
::::::::::::::.:::::..::::: :::.:::::::::::::.:::.::::::::::
NP_997 ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVNDIKNHKWFAT
240 250 260 270 280 290
310 320 330 340 350
pF1KB6 TSWIAIYEKKVEAPFIPKYTGPGDASNFDDYEEEELRISINEKCAKEFSEF
:.:::::..:::::::::. ::::.::::::::::.:.::::::.::::::
NP_997 TDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCGKEFSEF
300 310 320 330 340
>>NP_001291278 (OMIM: 601639,615830) cAMP-dependent prot (427 aa)
initn: 1974 init1: 1974 opt: 1974 Z-score: 815.3 bits: 159.6 E(85289): 1.1e-38
Smith-Waterman score: 1974; 84.2% identity (96.4% similar) in 336 aa overlap (16-351:92-427)
10 20 30 40
pF1KB6 MGNAPAKKDTEQEESVNEFLAKARGDFLYRWGNPAQNTASSDQFE
:.::::::. ::: .: .:::::: ::::
NP_001 PGLPREGARGTAKSQGYKYLGWRRPWPWNVVKEFLAKAKEDFLKKWESPAQNTAHLDQFE
70 80 90 100 110 120
50 60 70 80 90 100
pF1KB6 RLRTLGMGSFGRVMLVRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAIDFPFLV
:..::: :::::::::.:.:::.:::::::.::::::.::.:: :::::::::..:::::
NP_001 RIKTLGTGSFGRVMLVKHKETGNHYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLV
130 140 150 160 170 180
110 120 130 140 150 160
pF1KB6 KLQFSFKDNSYLYLVMEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLHSLDLIH
::.::::::: ::.::::::::::::.:.:.:::::::: :::::.::. .::::::::.
NP_001 KLEFSFKDNSNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIY
190 200 210 220 230 240
170 180 190 200 210 220
pF1KB6 RDLKPENLLIDQQGYLQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWAL
:::::::::::::::.::::::::::::::::::::::::::::::::::::::::::::
NP_001 RDLKPENLLIDQQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWAL
250 260 270 280 290 300
230 240 250 260 270 280
pF1KB6 GVLIYEMAVGFPPFYADQPIQIYEKIVSGRVRFPSKLSSDLKHLLRSLLQVDLTKRFGNL
::::::::.:.:::.::::::::::::::.:::::..::::: :::.:::::::::::::
NP_001 GVLIYEMAAGYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNL
310 320 330 340 350 360
290 300 310 320 330 340
pF1KB6 RNGVGDIKNHKWFATTSWIAIYEKKVEAPFIPKYTGPGDASNFDDYEEEELRISINEKCA
.:::.:::::::::::.:::::..:::::::::. ::::.::::::::::.:.::::::.
NP_001 KNGVNDIKNHKWFATTDWIAIYQRKVEAPFIPKFKGPGDTSNFDDYEEEEIRVSINEKCG
370 380 390 400 410 420
350
pF1KB6 KEFSEF
::::::
NP_001 KEFSEF
>>NP_002722 (OMIM: 176892) cAMP-dependent protein kinase (351 aa)
initn: 1916 init1: 1916 opt: 1916 Z-score: 793.2 bits: 155.3 E(85289): 1.9e-37
Smith-Waterman score: 1916; 78.6% identity (93.7% similar) in 351 aa overlap (1-351:1-351)
10 20 30 40 50 60
pF1KB6 MGNAPAKKDTEQEESVNEFLAKARGDFLYRWGNPAQNTASSDQFERLRTLGMGSFGRVML
:::: . : . :::.::::::. ::: .: ::.::.:. ..::: .::: ::::::::
NP_002 MGNAATAKKGSEVESVKEFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVML
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 VRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAIDFPFLVKLQFSFKDNSYLYLV
:.:. : .::::::.::::::.::.:: :::::::::..:::::.:...::::: ::.:
NP_002 VKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 MEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLHSLDLIHRDLKPENLLIDQQGY
:::::::::::.:.:.:::::::: :::::.::. .::::::::.:::::::::::.:::
NP_002 MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGY
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 LQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAVGFPPFY
.::::::::::::::::::::::::::::::::::::::::::::::::::::.:.:::.
NP_002 IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 ADQPIQIYEKIVSGRVRFPSKLSSDLKHLLRSLLQVDLTKRFGNLRNGVGDIKNHKWFAT
::::::::::::::.:::::..::::: :::.:::::::::::::.:::.:::.::::::
NP_002 ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFAT
250 260 270 280 290 300
310 320 330 340 350
pF1KB6 TSWIAIYEKKVEAPFIPKYTGPGDASNFDDYEEEELRISINEKCAKEFSEF
:.:::::..:::::::::. : ::.:::::::::..:.::.:::::::.::
NP_002 TDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEEDIRVSITEKCAKEFGEF
310 320 330 340 350
>>XP_006710821 (OMIM: 176892) PREDICTED: cAMP-dependent (354 aa)
initn: 1887 init1: 1887 opt: 1888 Z-score: 782.1 bits: 153.2 E(85289): 7.9e-37
Smith-Waterman score: 1888; 77.9% identity (94.0% similar) in 349 aa overlap (3-351:6-354)
10 20 30 40 50
pF1KB6 MGNAPAKKDTEQEESVNEFLAKARGDFLYRWGNPAQNTASSDQFERLRTLGMGSFGR
.. :. . .: ::.::::::. ::: .: ::.::.:. ..::: .::: :::::
XP_006 MSARKSSDASACSSSEISVKEFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGR
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB6 VMLVRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAIDFPFLVKLQFSFKDNSYL
::::.:. : .::::::.::::::.::.:: :::::::::..:::::.:...::::: :
XP_006 VMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNL
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB6 YLVMEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLHSLDLIHRDLKPENLLIDQ
:.::::::::::::.:.:.:::::::: :::::.::. .::::::::.:::::::::::.
XP_006 YMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDH
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB6 QGYLQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAVGFP
:::.::::::::::::::::::::::::::::::::::::::::::::::::::::.:.:
XP_006 QGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYP
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB6 PFYADQPIQIYEKIVSGRVRFPSKLSSDLKHLLRSLLQVDLTKRFGNLRNGVGDIKNHKW
::.::::::::::::::.:::::..::::: :::.:::::::::::::.:::.:::.:::
XP_006 PFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKW
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB6 FATTSWIAIYEKKVEAPFIPKYTGPGDASNFDDYEEEELRISINEKCAKEFSEF
::::.:::::..:::::::::. : ::.:::::::::..:.::.:::::::.::
XP_006 FATTDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEEDIRVSITEKCAKEFGEF
310 320 330 340 350
>>NP_001229788 (OMIM: 176892) cAMP-dependent protein kin (355 aa)
initn: 1887 init1: 1887 opt: 1888 Z-score: 782.1 bits: 153.2 E(85289): 7.9e-37
Smith-Waterman score: 1888; 77.9% identity (94.0% similar) in 349 aa overlap (3-351:7-355)
10 20 30 40 50
pF1KB6 MGNAPAKKDTEQEESVNEFLAKARGDFLYRWGNPAQNTASSDQFERLRTLGMGSFG
.. :. . .: ::.::::::. ::: .: ::.::.:. ..::: .::: ::::
NP_001 MGLSRKSSDASACSSSEISVKEFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFG
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB6 RVMLVRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAIDFPFLVKLQFSFKDNSY
:::::.:. : .::::::.::::::.::.:: :::::::::..:::::.:...:::::
NP_001 RVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSN
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB6 LYLVMEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLHSLDLIHRDLKPENLLID
::.::::::::::::.:.:.:::::::: :::::.::. .::::::::.:::::::::::
NP_001 LYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLID
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB6 QQGYLQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAVGF
.:::.::::::::::::::::::::::::::::::::::::::::::::::::::::.:.
NP_001 HQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGY
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB6 PPFYADQPIQIYEKIVSGRVRFPSKLSSDLKHLLRSLLQVDLTKRFGNLRNGVGDIKNHK
:::.::::::::::::::.:::::..::::: :::.:::::::::::::.:::.:::.::
NP_001 PPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHK
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB6 WFATTSWIAIYEKKVEAPFIPKYTGPGDASNFDDYEEEELRISINEKCAKEFSEF
:::::.:::::..:::::::::. : ::.:::::::::..:.::.:::::::.::
NP_001 WFATTDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEEDIRVSITEKCAKEFGEF
310 320 330 340 350
>>XP_005271075 (OMIM: 176892) PREDICTED: cAMP-dependent (346 aa)
initn: 1887 init1: 1887 opt: 1887 Z-score: 781.8 bits: 153.1 E(85289): 8.3e-37
Smith-Waterman score: 1887; 79.2% identity (94.7% similar) in 342 aa overlap (10-351:5-346)
10 20 30 40 50 60
pF1KB6 MGNAPAKKDTEQEESVNEFLAKARGDFLYRWGNPAQNTASSDQFERLRTLGMGSFGRVML
. .: ::.::::::. ::: .: ::.::.:. ..::: .::: ::::::::
XP_005 MSACSSSEISVKEFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVML
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 VRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAIDFPFLVKLQFSFKDNSYLYLV
:.:. : .::::::.::::::.::.:: :::::::::..:::::.:...::::: ::.:
XP_005 VKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMV
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB6 MEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLHSLDLIHRDLKPENLLIDQQGY
:::::::::::.:.:.:::::::: :::::.::. .::::::::.:::::::::::.:::
XP_005 MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGY
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB6 LQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAVGFPPFY
.::::::::::::::::::::::::::::::::::::::::::::::::::::.:.:::.
XP_005 IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB6 ADQPIQIYEKIVSGRVRFPSKLSSDLKHLLRSLLQVDLTKRFGNLRNGVGDIKNHKWFAT
::::::::::::::.:::::..::::: :::.:::::::::::::.:::.:::.::::::
XP_005 ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFAT
240 250 260 270 280 290
310 320 330 340 350
pF1KB6 TSWIAIYEKKVEAPFIPKYTGPGDASNFDDYEEEELRISINEKCAKEFSEF
:.:::::..:::::::::. : ::.:::::::::..:.::.:::::::.::
XP_005 TDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEEDIRVSITEKCAKEFGEF
300 310 320 330 340
>>XP_005271074 (OMIM: 176892) PREDICTED: cAMP-dependent (347 aa)
initn: 1887 init1: 1887 opt: 1887 Z-score: 781.8 bits: 153.1 E(85289): 8.3e-37
Smith-Waterman score: 1887; 79.2% identity (94.7% similar) in 342 aa overlap (10-351:6-347)
10 20 30 40 50 60
pF1KB6 MGNAPAKKDTEQEESVNEFLAKARGDFLYRWGNPAQNTASSDQFERLRTLGMGSFGRVML
. .: ::.::::::. ::: .: ::.::.:. ..::: .::: ::::::::
XP_005 MGLSCSSSEISVKEFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGSFGRVML
10 20 30 40 50
70 80 90 100 110 120
pF1KB6 VRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAIDFPFLVKLQFSFKDNSYLYLV
:.:. : .::::::.::::::.::.:: :::::::::..:::::.:...::::: ::.:
XP_005 VKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDNSNLYMV
60 70 80 90 100 110
130 140 150 160 170 180
pF1KB6 MEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLHSLDLIHRDLKPENLLIDQQGY
:::::::::::.:.:.:::::::: :::::.::. .::::::::.:::::::::::.:::
XP_005 MEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLLIDHQGY
120 130 140 150 160 170
190 200 210 220 230 240
pF1KB6 LQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAVGFPPFY
.::::::::::::::::::::::::::::::::::::::::::::::::::::.:.:::.
XP_005 IQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAAGYPPFF
180 190 200 210 220 230
250 260 270 280 290 300
pF1KB6 ADQPIQIYEKIVSGRVRFPSKLSSDLKHLLRSLLQVDLTKRFGNLRNGVGDIKNHKWFAT
::::::::::::::.:::::..::::: :::.:::::::::::::.:::.:::.::::::
XP_005 ADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKTHKWFAT
240 250 260 270 280 290
310 320 330 340 350
pF1KB6 TSWIAIYEKKVEAPFIPKYTGPGDASNFDDYEEEELRISINEKCAKEFSEF
:.:::::..:::::::::. : ::.:::::::::..:.::.:::::::.::
XP_005 TDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEEDIRVSITEKCAKEFGEF
300 310 320 330 340
>>NP_001229789 (OMIM: 176892) cAMP-dependent protein kin (357 aa)
initn: 1879 init1: 1879 opt: 1886 Z-score: 781.3 bits: 153.1 E(85289): 8.8e-37
Smith-Waterman score: 1886; 78.0% identity (94.0% similar) in 350 aa overlap (3-351:8-357)
10 20 30 40 50
pF1KB6 MGNAPAKKDTEQEES-VNEFLAKARGDFLYRWGNPAQNTASSDQFERLRTLGMGS
.: : ...: .: :.::::::. ::: .: ::.::.:. ..::: .::: ::
NP_001 MSARKSSDASACSSSEISDSFVKEFLAKAKEDFLKKWENPTQNNAGLEDFERKKTLGTGS
10 20 30 40 50 60
60 70 80 90 100 110
pF1KB6 FGRVMLVRHQETGGHYAMKILNKQKVVKMKQVEHILNEKRILQAIDFPFLVKLQFSFKDN
:::::::.:. : .::::::.::::::.::.:: :::::::::..:::::.:...::::
NP_001 FGRVMLVKHKATEQYYAMKILDKQKVVKLKQIEHTLNEKRILQAVNFPFLVRLEYAFKDN
70 80 90 100 110 120
120 130 140 150 160 170
pF1KB6 SYLYLVMEYVPGGEMFSRLQRVGRFSEPHACFYAAQVVLAVQYLHSLDLIHRDLKPENLL
: ::.::::::::::::.:.:.:::::::: :::::.::. .::::::::.:::::::::
NP_001 SNLYMVMEYVPGGEMFSHLRRIGRFSEPHARFYAAQIVLTFEYLHSLDLIYRDLKPENLL
130 140 150 160 170 180
180 190 200 210 220 230
pF1KB6 IDQQGYLQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAV
::.:::.::::::::::::::::::::::::::::::::::::::::::::::::::::.
NP_001 IDHQGYIQVTDFGFAKRVKGRTWTLCGTPEYLAPEIILSKGYNKAVDWWALGVLIYEMAA
190 200 210 220 230 240
240 250 260 270 280 290
pF1KB6 GFPPFYADQPIQIYEKIVSGRVRFPSKLSSDLKHLLRSLLQVDLTKRFGNLRNGVGDIKN
:.:::.::::::::::::::.:::::..::::: :::.:::::::::::::.:::.:::.
NP_001 GYPPFFADQPIQIYEKIVSGKVRFPSHFSSDLKDLLRNLLQVDLTKRFGNLKNGVSDIKT
250 260 270 280 290 300
300 310 320 330 340 350
pF1KB6 HKWFATTSWIAIYEKKVEAPFIPKYTGPGDASNFDDYEEEELRISINEKCAKEFSEF
:::::::.:::::..:::::::::. : ::.:::::::::..:.::.:::::::.::
NP_001 HKWFATTDWIAIYQRKVEAPFIPKFRGSGDTSNFDDYEEEDIRVSITEKCAKEFGEF
310 320 330 340 350
351 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 00:59:30 2016 done: Sat Nov 5 00:59:31 2016
Total Scan time: 6.910 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]