FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6504, 382 aa 1>>>pF1KB6504 382 - 382 aa - 382 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.1840+/-0.000302; mu= 17.6312+/- 0.019 mean_var=70.1544+/-14.369, 0's: 0 Z-trim(118.0): 11 B-trim: 1796 in 2/52 Lambda= 0.153125 statistics sampled from 30589 (30595) to 30589 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.735), E-opt: 0.2 (0.359), width: 16 Scan time: 9.120 The best scores are: opt bits E(85289) NP_036545 (OMIM: 607065) glutaminyl-peptide cyclot ( 361) 1081 247.6 3.5e-65 >>NP_036545 (OMIM: 607065) glutaminyl-peptide cyclotrans (361 aa) initn: 1064 init1: 473 opt: 1081 Z-score: 1291.1 bits: 247.6 E(85289): 3.5e-65 Smith-Waterman score: 1081; 47.8% identity (71.4% similar) in 364 aa overlap (27-382:7-361) 10 20 30 40 50 pF1KB6 MRSGGRGRPRLRLGERGLMEPLLPPKRRLLPRVRLLPLLLALAVGS-AFYTIWSGWHRRT ::.. ..:: :. :: .: . :.: NP_036 MAGGRHRRVVGTLHLLLLVAALPWASRGVSPSASAW---- 10 20 30 60 70 80 90 100 110 pF1KB6 EELPLGRELRVPLIGSLPEARLRRVVGQLDPQRLWSTYLRPLLVVRTPGSPGNLQVRKFL : .. . : : : . ::... . ...:.. :.:::. : :::::. .:. . NP_036 ---PEEKNYHQPAI--LNSSALRQIAEGTSISEMWQNDLQPLLIERYPGSPGSYAARQHI 40 50 60 70 80 90 120 130 140 150 160 170 pF1KB6 EATLRSLTAGWHVELDPFTASTPLGPVDFGNVVATLDPRAARHLTLACHYDSKLFPP-GS .. : : : .:.: : ..:: : .:.:...::.: : :::.:::::::: : .. NP_036 MQRIQRLQADWVLEIDTFLSQTPYGYRSFSNIISTLNPTAKRHLVLACHYDSKYFSHWNN 100 110 120 130 140 150 180 190 200 210 220 230 pF1KB6 TPFVGATDSAVPCALLLELAQALD---LELSRAKKQAAPVTLQLLFLDGEEALKEWGPKD ::::::::::::..::::.::: : :. .. . ..:::.:.:::::. .:.:.: NP_036 RVFVGATDSAVPCAMMLELARALDKKLLSLKTVSDSKPDLSLQLIFFDGEEAFLHWSPQD 160 170 180 190 200 210 240 250 260 270 280 290 pF1KB6 SLYGSRHLAQLMESIPHSPGP---TRIQAIELFMLLDLLGAPNPTFYSHFPRTVRWFHRL ::::::::: : : :: :: .......:..::::.::::::: . :: ..:::.:: NP_036 SLYGSRHLAAKMASTPHPPGARGTSQLHGMDLLVLLDLIGAPNPTFPNFFPNSARWFERL 220 230 240 250 260 270 300 310 320 330 340 350 pF1KB6 RSIEKRLHRLNLLQSHPQEVMYFQPGEPFGSVEDDHIPFLRRGVPVLHLISTPFPAVWHT ..::..::.:.::..: : ::: : ..::::::::::::::::: .::: :::: NP_036 QAIEHELHELGLLKDHSLEGRYFQNYSYGGVIQDDHIPFLRRGVPVLHLIPSPFPEVWHT 280 290 300 310 320 330 360 370 380 pF1KB6 PADTEVNLHPPTVHNLCRILAVFLAEYLGL :.: :: :. :: .:: ::. ::: : NP_036 MDDNEENLDESTIDNLNKILQVFVLEYLHL 340 350 360 382 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 17:10:10 2016 done: Fri Nov 4 17:10:11 2016 Total Scan time: 9.120 Total Display time: -0.030 Function used was FASTA [36.3.4 Apr, 2011]