Result of FASTA (ccds) for
pF1KB6505
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6505, 358 aa
1>>>pF1KB6505 358 - 358 aa - 358 aa
Library: human.CCDS.faa
18511270 residues in 32554 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.7729+/-0.000916; mu= 0.4797+/- 0.054
mean_var=240.4901+/-52.594, 0's: 0 Z-trim(112.8): 295 B-trim: 5 in 2/51
Lambda= 0.082704
statistics sampled from 13159 (13524) to 13159 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.756), E-opt: 0.2 (0.415), width: 16
Scan time: 2.840
The best scores are: opt bits E(32554)
CCDS12997.1 TRIB3 gene_id:57761|Hs108|chr20 ( 358) 2446 304.7 7.9e-83
CCDS77554.1 TRIB3 gene_id:57761|Hs108|chr20 ( 385) 2446 304.7 8.3e-83
CCDS6357.1 TRIB1 gene_id:10221|Hs108|chr8 ( 372) 988 130.8 1.9e-30
CCDS1683.1 TRIB2 gene_id:28951|Hs108|chr2 ( 343) 979 129.6 3.7e-30
CCDS64971.1 TRIB1 gene_id:10221|Hs108|chr8 ( 206) 766 104.0 1.2e-22
>>CCDS12997.1 TRIB3 gene_id:57761|Hs108|chr20 (358 aa)
initn: 2446 init1: 2446 opt: 2446 Z-score: 1600.5 bits: 304.7 E(32554): 7.9e-83
Smith-Waterman score: 2446; 100.0% identity (100.0% similar) in 358 aa overlap (1-358:1-358)
10 20 30 40 50 60
pF1KB6 MRATPLAAPAGSLSRKKRLELDDNLDTERPVQKRARSGPQPRLPPCLLPLSPPTAPDRAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 MRATPLAAPAGSLSRKKRLELDDNLDTERPVQKRARSGPQPRLPPCLLPLSPPTAPDRAT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 AVATASRLGPYVLLEPEEGGRAYQALHCPTGTEYTCKVYPVQEALAVLEPYARLPPHKHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 AVATASRLGPYVLLEPEEGGRAYQALHCPTGTEYTCKVYPVQEALAVLEPYARLPPHKHV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 ARPTEVLAGTQLLYAFFTRTHGDMHSLVRSRHRIPEPEAAVLFRQMATALAHCHQHGLVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 ARPTEVLAGTQLLYAFFTRTHGDMHSLVRSRHRIPEPEAAVLFRQMATALAHCHQHGLVL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 RDLKLCRFVFADRERKKLVLENLEDSCVLTGPDDSLWDKHACPAYVGPEILSSRASYSGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 RDLKLCRFVFADRERKKLVLENLEDSCVLTGPDDSLWDKHACPAYVGPEILSSRASYSGK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 AADVWSLGVALFTMLAGHYPFQDSEPVLLFGKIRRGAYALPAGLSAPARCLVRCLLRREP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 AADVWSLGVALFTMLAGHYPFQDSEPVLLFGKIRRGAYALPAGLSAPARCLVRCLLRREP
250 260 270 280 290 300
310 320 330 340 350
pF1KB6 AERLTATGILLHPWLRQDPMPLAPTRSHLWEAAQVVPDGLGLDEAREEEGDREVVLYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS12 AERLTATGILLHPWLRQDPMPLAPTRSHLWEAAQVVPDGLGLDEAREEEGDREVVLYG
310 320 330 340 350
>>CCDS77554.1 TRIB3 gene_id:57761|Hs108|chr20 (385 aa)
initn: 2446 init1: 2446 opt: 2446 Z-score: 1600.1 bits: 304.7 E(32554): 8.3e-83
Smith-Waterman score: 2446; 100.0% identity (100.0% similar) in 358 aa overlap (1-358:28-385)
10 20 30
pF1KB6 MRATPLAAPAGSLSRKKRLELDDNLDTERPVQK
:::::::::::::::::::::::::::::::::
CCDS77 MVLMHLAVKNNRMSANNDHFLTPTWQQMRATPLAAPAGSLSRKKRLELDDNLDTERPVQK
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB6 RARSGPQPRLPPCLLPLSPPTAPDRATAVATASRLGPYVLLEPEEGGRAYQALHCPTGTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 RARSGPQPRLPPCLLPLSPPTAPDRATAVATASRLGPYVLLEPEEGGRAYQALHCPTGTE
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB6 YTCKVYPVQEALAVLEPYARLPPHKHVARPTEVLAGTQLLYAFFTRTHGDMHSLVRSRHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 YTCKVYPVQEALAVLEPYARLPPHKHVARPTEVLAGTQLLYAFFTRTHGDMHSLVRSRHR
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB6 IPEPEAAVLFRQMATALAHCHQHGLVLRDLKLCRFVFADRERKKLVLENLEDSCVLTGPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 IPEPEAAVLFRQMATALAHCHQHGLVLRDLKLCRFVFADRERKKLVLENLEDSCVLTGPD
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB6 DSLWDKHACPAYVGPEILSSRASYSGKAADVWSLGVALFTMLAGHYPFQDSEPVLLFGKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 DSLWDKHACPAYVGPEILSSRASYSGKAADVWSLGVALFTMLAGHYPFQDSEPVLLFGKI
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB6 RRGAYALPAGLSAPARCLVRCLLRREPAERLTATGILLHPWLRQDPMPLAPTRSHLWEAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
CCDS77 RRGAYALPAGLSAPARCLVRCLLRREPAERLTATGILLHPWLRQDPMPLAPTRSHLWEAA
310 320 330 340 350 360
340 350
pF1KB6 QVVPDGLGLDEAREEEGDREVVLYG
:::::::::::::::::::::::::
CCDS77 QVVPDGLGLDEAREEEGDREVVLYG
370 380
>>CCDS6357.1 TRIB1 gene_id:10221|Hs108|chr8 (372 aa)
initn: 1022 init1: 928 opt: 988 Z-score: 660.2 bits: 130.8 E(32554): 1.9e-30
Smith-Waterman score: 988; 46.5% identity (70.2% similar) in 346 aa overlap (2-338:17-360)
10 20 30 40
pF1KB6 MRATPLAAPAG-SLSRKKRLELDDN--LDTERPVQKRARSGPQ--
:. : :: .. :. :. :: . .. : .. : :.
CCDS63 MRVGPVRSAMSGASQPRGPALLFPATRGVPAKRLLDADDAAAVAAKCPRLSECSSPPDYL
10 20 30 40 50 60
50 60 70 80 90
pF1KB6 -PRLPPCLLPLSPPTAPDRATAVATA---SRLGPYVLLEPEEGGRAYQALHCPTGTEYTC
: :: : ::.:: . . ..: ::.. :.:: : .. .:: :: : :
CCDS63 SPPGSPCS-PQPPPAAPGAGGGSGSAPGPSRIADYLLLPLAEREHVSRALCIHTGRELRC
70 80 90 100 110
100 110 120 130 140 150
pF1KB6 KVYPVQEALAVLEPYARLPPHKHVARPTEVLAGTQLLYAFFTRTHGDMHSLVRSRHRIPE
::.:... ..:: .:: :.... .::. : :.:: . ::::: ::::.:. :
CCDS63 KVFPIKHYQDKIRPYIQLPSHSNITGIVEVILGETKAYVFFEKDFGDMHSYVRSRKRLRE
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB6 PEAAVLFRQMATALAHCHQHGLVLRDLKLCRFVFADRERKKLVLENLEDSCVLTGPDDSL
::: ::.:...:.::::: ..:: :::: .:::. .:: .: ::.:::. .. : ::.:
CCDS63 EEAARLFKQIVSAVAHCHQSAIVLGDLKLRKFVFSTEERTQLRLESLEDTHIMKGEDDAL
180 190 200 210 220 230
220 230 240 250 260 270
pF1KB6 WDKHACPAYVGPEILSSRASYSGKAADVWSLGVALFTMLAGHYPFQDSEPVLLFGKIRRG
:::.:::::.::::.. ..::::::::::::: :.:.:.:.:::.::.: ::.:::::
CCDS63 SDKHGCPAYVSPEILNTTGTYSGKAADVWSLGVMLYTLLVGRYPFHDSDPSALFSKIRRG
240 250 260 270 280 290
280 290 300 310 320 330
pF1KB6 AYALPAGLSAPARCLVRCLLRREPAERLTATGILLHPWLRQDPMPLAPTRSHLWEAAQVV
. .: .: ::::.: ::::::.::::: ::::::... : . :.. . :.:
CCDS63 QFCIPEHISPKARCLIRSLLRREPSERLTAPEILLHPWFESVLEP-GYIDSEIGTSDQIV
300 310 320 330 340 350
340 350
pF1KB6 PDGLGLDEAREEEGDREVVLYG
:.
CCDS63 PEYQEDSDISSFFC
360 370
>>CCDS1683.1 TRIB2 gene_id:28951|Hs108|chr2 (343 aa)
initn: 947 init1: 947 opt: 979 Z-score: 654.8 bits: 129.6 E(32554): 3.7e-30
Smith-Waterman score: 993; 47.0% identity (71.0% similar) in 338 aa overlap (2-338:5-331)
10 20 30 40 50
pF1KB6 MRATPLAAPAGSLSRKKRLELDDNLDTERPVQKRARSGPQPRLPPCLLPLSPPTAPD
:.::.. . ::.: .... :.. : .. :. . : : ::: .:.
CCDS16 MNIHRSTPITIARYGRSRNKTQDFEE-LSSIRSAE------PSQSFSPNLGSPSPPETPN
10 20 30 40 50
60 70 80 90 100 110
pF1KB6 RATAVATASRLGPYVLLEPEEGGRAYQALHCPTGTEYTCKVYPVQEALAVLEPYARLPPH
. : : .: :.:::: :: ....:.: .: : .:::. .. : : : :
CCDS16 LSHCV---SCIGKYLLLEPLEGDHVFRAVHLHSGEELVCKVFDISCYQESLAPCFCLSAH
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 KHVARPTEVLAGTQLLYAFFTRTHGDMHSLVRSRHRIPEPEAAVLFRQMATALAHCHQHG
... . ::.. : :.:: :..:::::.::. ... : ::: :: :.:.:.::::. :
CCDS16 SNINQITEIILGETKAYVFFERSYGDMHSFVRTCKKLREEEAARLFYQIASAVAHCHDGG
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB6 LVLRDLKLCRFVFADRERKKLVLENLEDSCVLTGPDDSLWDKHACPAYVGPEILSSRASY
:::::::: .:.: :.:: .. ::.:::. .: : :::: :::.:::::.::::.. .::
CCDS16 LVLRDLKLRKFIFKDEERTRVKLESLEDAYILRGDDDSLSDKHGCPAYVSPEILNTSGSY
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB6 SGKAADVWSLGVALFTMLAGHYPFQDSEPVLLFGKIRRGAYALPAGLSAPARCLVRCLLR
:::::::::::: :.:::.:.:::.: :: ::.::::: . .: :: :.::.: .::
CCDS16 SGKAADVWSLGVMLYTMLVGRYPFHDIEPSSLFSKIRRGQFNIPETLSPKAKCLIRSILR
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB6 REPAERLTATGILLHPWLRQDPMPLAPTRSHLWEAA-QVVPDGLGLDEAREEEGDREVVL
:::.::::. :: :::. : . .. . :.. :.:::
CCDS16 REPSERLTSQEILDHPWFSTD-FSVSNSAYGAKEVSDQLVPDVNMEENLDPFFN
300 310 320 330 340
pF1KB6 YG
>>CCDS64971.1 TRIB1 gene_id:10221|Hs108|chr8 (206 aa)
initn: 774 init1: 754 opt: 766 Z-score: 520.3 bits: 104.0 E(32554): 1.2e-22
Smith-Waterman score: 766; 57.9% identity (81.0% similar) in 195 aa overlap (144-338:1-194)
120 130 140 150 160 170
pF1KB6 LPPHKHVARPTEVLAGTQLLYAFFTRTHGDMHSLVRSRHRIPEPEAAVLFRQMATALAHC
::: ::::.:. : ::: ::.:...:.:::
CCDS64 MHSYVRSRKRLREEEAARLFKQIVSAVAHC
10 20 30
180 190 200 210 220 230
pF1KB6 HQHGLVLRDLKLCRFVFADRERKKLVLENLEDSCVLTGPDDSLWDKHACPAYVGPEILSS
:: ..:: :::: .:::. .:: .: ::.:::. .. : ::.: :::.:::::.::::..
CCDS64 HQSAIVLGDLKLRKFVFSTEERTQLRLESLEDTHIMKGEDDALSDKHGCPAYVSPEILNT
40 50 60 70 80 90
240 250 260 270 280 290
pF1KB6 RASYSGKAADVWSLGVALFTMLAGHYPFQDSEPVLLFGKIRRGAYALPAGLSAPARCLVR
..::::::::::::: :.:.:.:.:::.::.: ::.::::: . .: .: ::::.:
CCDS64 TGTYSGKAADVWSLGVMLYTLLVGRYPFHDSDPSALFSKIRRGQFCIPEHISPKARCLIR
100 110 120 130 140 150
300 310 320 330 340 350
pF1KB6 CLLRREPAERLTATGILLHPWLRQDPMPLAPTRSHLWEAAQVVPDGLGLDEAREEEGDRE
::::::.::::: ::::::... : . :.. . :.::.
CCDS64 SLLRREPSERLTAPEILLHPWFESVLEP-GYIDSEIGTSDQIVPEYQEDSDISSFFC
160 170 180 190 200
pF1KB6 VVLYG
358 residues in 1 query sequences
18511270 residues in 32554 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 16:20:49 2016 done: Fri Nov 4 16:20:49 2016
Total Scan time: 2.840 Total Display time: 0.010
Function used was FASTA [36.3.4 Apr, 2011]