Result of FASTA (omim) for
pF1KB6505
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6505, 358 aa
1>>>pF1KB6505 358 - 358 aa - 358 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 8.9748+/-0.000408; mu= 0.2781+/- 0.025
mean_var=395.2673+/-87.747, 0's: 0 Z-trim(120.3): 742 B-trim: 904 in 1/55
Lambda= 0.064510
statistics sampled from 34319 (35358) to 34319 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.754), E-opt: 0.2 (0.415), width: 16
Scan time: 9.540
The best scores are: opt bits E(85289)
NP_001288117 (OMIM: 607898) tribbles homolog 3 iso ( 358) 2446 241.8 1.8e-63
NP_001288122 (OMIM: 607898) tribbles homolog 3 iso ( 358) 2446 241.8 1.8e-63
NP_066981 (OMIM: 607898) tribbles homolog 3 isofor ( 358) 2446 241.8 1.8e-63
NP_001288119 (OMIM: 607898) tribbles homolog 3 iso ( 358) 2446 241.8 1.8e-63
NP_001288125 (OMIM: 607898) tribbles homolog 3 iso ( 358) 2446 241.8 1.8e-63
NP_001288130 (OMIM: 607898) tribbles homolog 3 iso ( 385) 2446 241.8 1.9e-63
XP_016883478 (OMIM: 607898) PREDICTED: tribbles ho ( 385) 2446 241.8 1.9e-63
NP_079471 (OMIM: 609461) tribbles homolog 1 isofor ( 372) 988 106.1 1.3e-22
NP_067675 (OMIM: 609462) tribbles homolog 2 [Homo ( 343) 979 105.2 2.2e-22
NP_001269914 (OMIM: 609461) tribbles homolog 1 iso ( 206) 766 85.1 1.5e-16
NP_115806 (OMIM: 609235) serine/threonine-protein ( 778) 394 51.3 8.7e-06
XP_011516388 (OMIM: 607025) PREDICTED: maternal em ( 373) 386 50.1 9.6e-06
XP_011516382 (OMIM: 607025) PREDICTED: maternal em ( 622) 390 50.8 9.9e-06
NP_001243614 (OMIM: 607025) maternal embryonic leu ( 610) 386 50.4 1.3e-05
XP_011516386 (OMIM: 607025) PREDICTED: maternal em ( 619) 386 50.4 1.3e-05
XP_011516385 (OMIM: 607025) PREDICTED: maternal em ( 619) 386 50.4 1.3e-05
XP_011516383 (OMIM: 607025) PREDICTED: maternal em ( 619) 386 50.4 1.3e-05
NP_001243618 (OMIM: 607025) maternal embryonic leu ( 619) 386 50.4 1.3e-05
XP_011516384 (OMIM: 607025) PREDICTED: maternal em ( 619) 386 50.4 1.3e-05
XP_011516381 (OMIM: 607025) PREDICTED: maternal em ( 651) 386 50.4 1.3e-05
XP_011516380 (OMIM: 607025) PREDICTED: maternal em ( 651) 386 50.4 1.3e-05
NP_055606 (OMIM: 607025) maternal embryonic leucin ( 651) 386 50.4 1.3e-05
XP_011516378 (OMIM: 607025) PREDICTED: maternal em ( 651) 386 50.4 1.3e-05
XP_011516379 (OMIM: 607025) PREDICTED: maternal em ( 651) 386 50.4 1.3e-05
NP_114406 (OMIM: 609437) serine/threonine-protein ( 435) 373 49.0 2.4e-05
NP_001269476 (OMIM: 609437) serine/threonine-prote ( 435) 373 49.0 2.4e-05
NP_001269475 (OMIM: 609437) serine/threonine-prote ( 440) 373 49.0 2.4e-05
XP_011516387 (OMIM: 607025) PREDICTED: maternal em ( 568) 374 49.2 2.6e-05
NP_001243619 (OMIM: 607025) maternal embryonic leu ( 580) 374 49.2 2.7e-05
NP_004064 (OMIM: 602913) serine/threonine-protein ( 646) 374 49.3 2.8e-05
XP_006714393 (OMIM: 607708) PREDICTED: calcium/cal ( 478) 368 48.6 3.5e-05
NP_001308506 (OMIM: 607708) calcium/calmodulin-dep ( 491) 368 48.6 3.6e-05
XP_016864166 (OMIM: 607708) PREDICTED: calcium/cal ( 491) 368 48.6 3.6e-05
NP_001308512 (OMIM: 607708) calcium/calmodulin-dep ( 492) 368 48.6 3.6e-05
NP_001308504 (OMIM: 607708) calcium/calmodulin-dep ( 492) 368 48.6 3.6e-05
NP_001308497 (OMIM: 607708) calcium/calmodulin-dep ( 503) 368 48.6 3.6e-05
XP_011530597 (OMIM: 607708) PREDICTED: calcium/cal ( 510) 368 48.6 3.7e-05
XP_016864163 (OMIM: 607708) PREDICTED: calcium/cal ( 511) 368 48.6 3.7e-05
NP_001308501 (OMIM: 607708) calcium/calmodulin-dep ( 512) 368 48.6 3.7e-05
XP_016864162 (OMIM: 607708) PREDICTED: calcium/cal ( 512) 368 48.6 3.7e-05
NP_001308496 (OMIM: 607708) calcium/calmodulin-dep ( 512) 368 48.6 3.7e-05
XP_016864161 (OMIM: 607708) PREDICTED: calcium/cal ( 513) 368 48.6 3.7e-05
XP_005263311 (OMIM: 607708) PREDICTED: calcium/cal ( 532) 368 48.6 3.7e-05
NP_001308500 (OMIM: 607708) calcium/calmodulin-dep ( 533) 368 48.6 3.8e-05
NP_003948 (OMIM: 609236) serine/threonine-protein ( 668) 370 48.9 3.8e-05
NP_001243558 (OMIM: 609236) serine/threonine-prote ( 674) 370 49.0 3.8e-05
NP_001243559 (OMIM: 609236) serine/threonine-prote ( 766) 371 49.1 3.8e-05
XP_005253275 (OMIM: 609236) PREDICTED: serine/thre ( 720) 370 49.0 3.9e-05
NP_001243556 (OMIM: 609236) serine/threonine-prote ( 736) 370 49.0 4e-05
XP_006718437 (OMIM: 609236) PREDICTED: serine/thre ( 758) 370 49.0 4e-05
>>NP_001288117 (OMIM: 607898) tribbles homolog 3 isoform (358 aa)
initn: 2446 init1: 2446 opt: 2446 Z-score: 1260.5 bits: 241.8 E(85289): 1.8e-63
Smith-Waterman score: 2446; 100.0% identity (100.0% similar) in 358 aa overlap (1-358:1-358)
10 20 30 40 50 60
pF1KB6 MRATPLAAPAGSLSRKKRLELDDNLDTERPVQKRARSGPQPRLPPCLLPLSPPTAPDRAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRATPLAAPAGSLSRKKRLELDDNLDTERPVQKRARSGPQPRLPPCLLPLSPPTAPDRAT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 AVATASRLGPYVLLEPEEGGRAYQALHCPTGTEYTCKVYPVQEALAVLEPYARLPPHKHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVATASRLGPYVLLEPEEGGRAYQALHCPTGTEYTCKVYPVQEALAVLEPYARLPPHKHV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 ARPTEVLAGTQLLYAFFTRTHGDMHSLVRSRHRIPEPEAAVLFRQMATALAHCHQHGLVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARPTEVLAGTQLLYAFFTRTHGDMHSLVRSRHRIPEPEAAVLFRQMATALAHCHQHGLVL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 RDLKLCRFVFADRERKKLVLENLEDSCVLTGPDDSLWDKHACPAYVGPEILSSRASYSGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RDLKLCRFVFADRERKKLVLENLEDSCVLTGPDDSLWDKHACPAYVGPEILSSRASYSGK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 AADVWSLGVALFTMLAGHYPFQDSEPVLLFGKIRRGAYALPAGLSAPARCLVRCLLRREP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AADVWSLGVALFTMLAGHYPFQDSEPVLLFGKIRRGAYALPAGLSAPARCLVRCLLRREP
250 260 270 280 290 300
310 320 330 340 350
pF1KB6 AERLTATGILLHPWLRQDPMPLAPTRSHLWEAAQVVPDGLGLDEAREEEGDREVVLYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AERLTATGILLHPWLRQDPMPLAPTRSHLWEAAQVVPDGLGLDEAREEEGDREVVLYG
310 320 330 340 350
>>NP_001288122 (OMIM: 607898) tribbles homolog 3 isoform (358 aa)
initn: 2446 init1: 2446 opt: 2446 Z-score: 1260.5 bits: 241.8 E(85289): 1.8e-63
Smith-Waterman score: 2446; 100.0% identity (100.0% similar) in 358 aa overlap (1-358:1-358)
10 20 30 40 50 60
pF1KB6 MRATPLAAPAGSLSRKKRLELDDNLDTERPVQKRARSGPQPRLPPCLLPLSPPTAPDRAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRATPLAAPAGSLSRKKRLELDDNLDTERPVQKRARSGPQPRLPPCLLPLSPPTAPDRAT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 AVATASRLGPYVLLEPEEGGRAYQALHCPTGTEYTCKVYPVQEALAVLEPYARLPPHKHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVATASRLGPYVLLEPEEGGRAYQALHCPTGTEYTCKVYPVQEALAVLEPYARLPPHKHV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 ARPTEVLAGTQLLYAFFTRTHGDMHSLVRSRHRIPEPEAAVLFRQMATALAHCHQHGLVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARPTEVLAGTQLLYAFFTRTHGDMHSLVRSRHRIPEPEAAVLFRQMATALAHCHQHGLVL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 RDLKLCRFVFADRERKKLVLENLEDSCVLTGPDDSLWDKHACPAYVGPEILSSRASYSGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RDLKLCRFVFADRERKKLVLENLEDSCVLTGPDDSLWDKHACPAYVGPEILSSRASYSGK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 AADVWSLGVALFTMLAGHYPFQDSEPVLLFGKIRRGAYALPAGLSAPARCLVRCLLRREP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AADVWSLGVALFTMLAGHYPFQDSEPVLLFGKIRRGAYALPAGLSAPARCLVRCLLRREP
250 260 270 280 290 300
310 320 330 340 350
pF1KB6 AERLTATGILLHPWLRQDPMPLAPTRSHLWEAAQVVPDGLGLDEAREEEGDREVVLYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AERLTATGILLHPWLRQDPMPLAPTRSHLWEAAQVVPDGLGLDEAREEEGDREVVLYG
310 320 330 340 350
>>NP_066981 (OMIM: 607898) tribbles homolog 3 isoform 1 (358 aa)
initn: 2446 init1: 2446 opt: 2446 Z-score: 1260.5 bits: 241.8 E(85289): 1.8e-63
Smith-Waterman score: 2446; 100.0% identity (100.0% similar) in 358 aa overlap (1-358:1-358)
10 20 30 40 50 60
pF1KB6 MRATPLAAPAGSLSRKKRLELDDNLDTERPVQKRARSGPQPRLPPCLLPLSPPTAPDRAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 MRATPLAAPAGSLSRKKRLELDDNLDTERPVQKRARSGPQPRLPPCLLPLSPPTAPDRAT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 AVATASRLGPYVLLEPEEGGRAYQALHCPTGTEYTCKVYPVQEALAVLEPYARLPPHKHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 AVATASRLGPYVLLEPEEGGRAYQALHCPTGTEYTCKVYPVQEALAVLEPYARLPPHKHV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 ARPTEVLAGTQLLYAFFTRTHGDMHSLVRSRHRIPEPEAAVLFRQMATALAHCHQHGLVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 ARPTEVLAGTQLLYAFFTRTHGDMHSLVRSRHRIPEPEAAVLFRQMATALAHCHQHGLVL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 RDLKLCRFVFADRERKKLVLENLEDSCVLTGPDDSLWDKHACPAYVGPEILSSRASYSGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 RDLKLCRFVFADRERKKLVLENLEDSCVLTGPDDSLWDKHACPAYVGPEILSSRASYSGK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 AADVWSLGVALFTMLAGHYPFQDSEPVLLFGKIRRGAYALPAGLSAPARCLVRCLLRREP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 AADVWSLGVALFTMLAGHYPFQDSEPVLLFGKIRRGAYALPAGLSAPARCLVRCLLRREP
250 260 270 280 290 300
310 320 330 340 350
pF1KB6 AERLTATGILLHPWLRQDPMPLAPTRSHLWEAAQVVPDGLGLDEAREEEGDREVVLYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_066 AERLTATGILLHPWLRQDPMPLAPTRSHLWEAAQVVPDGLGLDEAREEEGDREVVLYG
310 320 330 340 350
>>NP_001288119 (OMIM: 607898) tribbles homolog 3 isoform (358 aa)
initn: 2446 init1: 2446 opt: 2446 Z-score: 1260.5 bits: 241.8 E(85289): 1.8e-63
Smith-Waterman score: 2446; 100.0% identity (100.0% similar) in 358 aa overlap (1-358:1-358)
10 20 30 40 50 60
pF1KB6 MRATPLAAPAGSLSRKKRLELDDNLDTERPVQKRARSGPQPRLPPCLLPLSPPTAPDRAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRATPLAAPAGSLSRKKRLELDDNLDTERPVQKRARSGPQPRLPPCLLPLSPPTAPDRAT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 AVATASRLGPYVLLEPEEGGRAYQALHCPTGTEYTCKVYPVQEALAVLEPYARLPPHKHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVATASRLGPYVLLEPEEGGRAYQALHCPTGTEYTCKVYPVQEALAVLEPYARLPPHKHV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 ARPTEVLAGTQLLYAFFTRTHGDMHSLVRSRHRIPEPEAAVLFRQMATALAHCHQHGLVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARPTEVLAGTQLLYAFFTRTHGDMHSLVRSRHRIPEPEAAVLFRQMATALAHCHQHGLVL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 RDLKLCRFVFADRERKKLVLENLEDSCVLTGPDDSLWDKHACPAYVGPEILSSRASYSGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RDLKLCRFVFADRERKKLVLENLEDSCVLTGPDDSLWDKHACPAYVGPEILSSRASYSGK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 AADVWSLGVALFTMLAGHYPFQDSEPVLLFGKIRRGAYALPAGLSAPARCLVRCLLRREP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AADVWSLGVALFTMLAGHYPFQDSEPVLLFGKIRRGAYALPAGLSAPARCLVRCLLRREP
250 260 270 280 290 300
310 320 330 340 350
pF1KB6 AERLTATGILLHPWLRQDPMPLAPTRSHLWEAAQVVPDGLGLDEAREEEGDREVVLYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AERLTATGILLHPWLRQDPMPLAPTRSHLWEAAQVVPDGLGLDEAREEEGDREVVLYG
310 320 330 340 350
>>NP_001288125 (OMIM: 607898) tribbles homolog 3 isoform (358 aa)
initn: 2446 init1: 2446 opt: 2446 Z-score: 1260.5 bits: 241.8 E(85289): 1.8e-63
Smith-Waterman score: 2446; 100.0% identity (100.0% similar) in 358 aa overlap (1-358:1-358)
10 20 30 40 50 60
pF1KB6 MRATPLAAPAGSLSRKKRLELDDNLDTERPVQKRARSGPQPRLPPCLLPLSPPTAPDRAT
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MRATPLAAPAGSLSRKKRLELDDNLDTERPVQKRARSGPQPRLPPCLLPLSPPTAPDRAT
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 AVATASRLGPYVLLEPEEGGRAYQALHCPTGTEYTCKVYPVQEALAVLEPYARLPPHKHV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AVATASRLGPYVLLEPEEGGRAYQALHCPTGTEYTCKVYPVQEALAVLEPYARLPPHKHV
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 ARPTEVLAGTQLLYAFFTRTHGDMHSLVRSRHRIPEPEAAVLFRQMATALAHCHQHGLVL
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ARPTEVLAGTQLLYAFFTRTHGDMHSLVRSRHRIPEPEAAVLFRQMATALAHCHQHGLVL
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 RDLKLCRFVFADRERKKLVLENLEDSCVLTGPDDSLWDKHACPAYVGPEILSSRASYSGK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RDLKLCRFVFADRERKKLVLENLEDSCVLTGPDDSLWDKHACPAYVGPEILSSRASYSGK
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 AADVWSLGVALFTMLAGHYPFQDSEPVLLFGKIRRGAYALPAGLSAPARCLVRCLLRREP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AADVWSLGVALFTMLAGHYPFQDSEPVLLFGKIRRGAYALPAGLSAPARCLVRCLLRREP
250 260 270 280 290 300
310 320 330 340 350
pF1KB6 AERLTATGILLHPWLRQDPMPLAPTRSHLWEAAQVVPDGLGLDEAREEEGDREVVLYG
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 AERLTATGILLHPWLRQDPMPLAPTRSHLWEAAQVVPDGLGLDEAREEEGDREVVLYG
310 320 330 340 350
>>NP_001288130 (OMIM: 607898) tribbles homolog 3 isoform (385 aa)
initn: 2446 init1: 2446 opt: 2446 Z-score: 1260.2 bits: 241.8 E(85289): 1.9e-63
Smith-Waterman score: 2446; 100.0% identity (100.0% similar) in 358 aa overlap (1-358:28-385)
10 20 30
pF1KB6 MRATPLAAPAGSLSRKKRLELDDNLDTERPVQK
:::::::::::::::::::::::::::::::::
NP_001 MVLMHLAVKNNRMSANNDHFLTPTWQQMRATPLAAPAGSLSRKKRLELDDNLDTERPVQK
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB6 RARSGPQPRLPPCLLPLSPPTAPDRATAVATASRLGPYVLLEPEEGGRAYQALHCPTGTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RARSGPQPRLPPCLLPLSPPTAPDRATAVATASRLGPYVLLEPEEGGRAYQALHCPTGTE
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB6 YTCKVYPVQEALAVLEPYARLPPHKHVARPTEVLAGTQLLYAFFTRTHGDMHSLVRSRHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 YTCKVYPVQEALAVLEPYARLPPHKHVARPTEVLAGTQLLYAFFTRTHGDMHSLVRSRHR
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB6 IPEPEAAVLFRQMATALAHCHQHGLVLRDLKLCRFVFADRERKKLVLENLEDSCVLTGPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 IPEPEAAVLFRQMATALAHCHQHGLVLRDLKLCRFVFADRERKKLVLENLEDSCVLTGPD
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB6 DSLWDKHACPAYVGPEILSSRASYSGKAADVWSLGVALFTMLAGHYPFQDSEPVLLFGKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSLWDKHACPAYVGPEILSSRASYSGKAADVWSLGVALFTMLAGHYPFQDSEPVLLFGKI
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB6 RRGAYALPAGLSAPARCLVRCLLRREPAERLTATGILLHPWLRQDPMPLAPTRSHLWEAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 RRGAYALPAGLSAPARCLVRCLLRREPAERLTATGILLHPWLRQDPMPLAPTRSHLWEAA
310 320 330 340 350 360
340 350
pF1KB6 QVVPDGLGLDEAREEEGDREVVLYG
:::::::::::::::::::::::::
NP_001 QVVPDGLGLDEAREEEGDREVVLYG
370 380
>>XP_016883478 (OMIM: 607898) PREDICTED: tribbles homolo (385 aa)
initn: 2446 init1: 2446 opt: 2446 Z-score: 1260.2 bits: 241.8 E(85289): 1.9e-63
Smith-Waterman score: 2446; 100.0% identity (100.0% similar) in 358 aa overlap (1-358:28-385)
10 20 30
pF1KB6 MRATPLAAPAGSLSRKKRLELDDNLDTERPVQK
:::::::::::::::::::::::::::::::::
XP_016 MVLMHLAVKNNRMSANNDHFLTPTWQQMRATPLAAPAGSLSRKKRLELDDNLDTERPVQK
10 20 30 40 50 60
40 50 60 70 80 90
pF1KB6 RARSGPQPRLPPCLLPLSPPTAPDRATAVATASRLGPYVLLEPEEGGRAYQALHCPTGTE
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RARSGPQPRLPPCLLPLSPPTAPDRATAVATASRLGPYVLLEPEEGGRAYQALHCPTGTE
70 80 90 100 110 120
100 110 120 130 140 150
pF1KB6 YTCKVYPVQEALAVLEPYARLPPHKHVARPTEVLAGTQLLYAFFTRTHGDMHSLVRSRHR
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 YTCKVYPVQEALAVLEPYARLPPHKHVARPTEVLAGTQLLYAFFTRTHGDMHSLVRSRHR
130 140 150 160 170 180
160 170 180 190 200 210
pF1KB6 IPEPEAAVLFRQMATALAHCHQHGLVLRDLKLCRFVFADRERKKLVLENLEDSCVLTGPD
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 IPEPEAAVLFRQMATALAHCHQHGLVLRDLKLCRFVFADRERKKLVLENLEDSCVLTGPD
190 200 210 220 230 240
220 230 240 250 260 270
pF1KB6 DSLWDKHACPAYVGPEILSSRASYSGKAADVWSLGVALFTMLAGHYPFQDSEPVLLFGKI
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 DSLWDKHACPAYVGPEILSSRASYSGKAADVWSLGVALFTMLAGHYPFQDSEPVLLFGKI
250 260 270 280 290 300
280 290 300 310 320 330
pF1KB6 RRGAYALPAGLSAPARCLVRCLLRREPAERLTATGILLHPWLRQDPMPLAPTRSHLWEAA
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_016 RRGAYALPAGLSAPARCLVRCLLRREPAERLTATGILLHPWLRQDPMPLAPTRSHLWEAA
310 320 330 340 350 360
340 350
pF1KB6 QVVPDGLGLDEAREEEGDREVVLYG
:::::::::::::::::::::::::
XP_016 QVVPDGLGLDEAREEEGDREVVLYG
370 380
>>NP_079471 (OMIM: 609461) tribbles homolog 1 isoform 1 (372 aa)
initn: 1022 init1: 928 opt: 988 Z-score: 527.0 bits: 106.1 E(85289): 1.3e-22
Smith-Waterman score: 988; 46.5% identity (70.2% similar) in 346 aa overlap (2-338:17-360)
10 20 30 40
pF1KB6 MRATPLAAPAG-SLSRKKRLELDDN--LDTERPVQKRARSGPQ--
:. : :: .. :. :. :: . .. : .. : :.
NP_079 MRVGPVRSAMSGASQPRGPALLFPATRGVPAKRLLDADDAAAVAAKCPRLSECSSPPDYL
10 20 30 40 50 60
50 60 70 80 90
pF1KB6 -PRLPPCLLPLSPPTAPDRATAVATA---SRLGPYVLLEPEEGGRAYQALHCPTGTEYTC
: :: : ::.:: . . ..: ::.. :.:: : .. .:: :: : :
NP_079 SPPGSPCS-PQPPPAAPGAGGGSGSAPGPSRIADYLLLPLAEREHVSRALCIHTGRELRC
70 80 90 100 110
100 110 120 130 140 150
pF1KB6 KVYPVQEALAVLEPYARLPPHKHVARPTEVLAGTQLLYAFFTRTHGDMHSLVRSRHRIPE
::.:... ..:: .:: :.... .::. : :.:: . ::::: ::::.:. :
NP_079 KVFPIKHYQDKIRPYIQLPSHSNITGIVEVILGETKAYVFFEKDFGDMHSYVRSRKRLRE
120 130 140 150 160 170
160 170 180 190 200 210
pF1KB6 PEAAVLFRQMATALAHCHQHGLVLRDLKLCRFVFADRERKKLVLENLEDSCVLTGPDDSL
::: ::.:...:.::::: ..:: :::: .:::. .:: .: ::.:::. .. : ::.:
NP_079 EEAARLFKQIVSAVAHCHQSAIVLGDLKLRKFVFSTEERTQLRLESLEDTHIMKGEDDAL
180 190 200 210 220 230
220 230 240 250 260 270
pF1KB6 WDKHACPAYVGPEILSSRASYSGKAADVWSLGVALFTMLAGHYPFQDSEPVLLFGKIRRG
:::.:::::.::::.. ..::::::::::::: :.:.:.:.:::.::.: ::.:::::
NP_079 SDKHGCPAYVSPEILNTTGTYSGKAADVWSLGVMLYTLLVGRYPFHDSDPSALFSKIRRG
240 250 260 270 280 290
280 290 300 310 320 330
pF1KB6 AYALPAGLSAPARCLVRCLLRREPAERLTATGILLHPWLRQDPMPLAPTRSHLWEAAQVV
. .: .: ::::.: ::::::.::::: ::::::... : . :.. . :.:
NP_079 QFCIPEHISPKARCLIRSLLRREPSERLTAPEILLHPWFESVLEP-GYIDSEIGTSDQIV
300 310 320 330 340 350
340 350
pF1KB6 PDGLGLDEAREEEGDREVVLYG
:.
NP_079 PEYQEDSDISSFFC
360 370
>>NP_067675 (OMIM: 609462) tribbles homolog 2 [Homo sapi (343 aa)
initn: 947 init1: 947 opt: 979 Z-score: 522.8 bits: 105.2 E(85289): 2.2e-22
Smith-Waterman score: 993; 47.0% identity (71.0% similar) in 338 aa overlap (2-338:5-331)
10 20 30 40 50
pF1KB6 MRATPLAAPAGSLSRKKRLELDDNLDTERPVQKRARSGPQPRLPPCLLPLSPPTAPD
:.::.. . ::.: .... :.. : .. :. . : : ::: .:.
NP_067 MNIHRSTPITIARYGRSRNKTQDFEE-LSSIRSAE------PSQSFSPNLGSPSPPETPN
10 20 30 40 50
60 70 80 90 100 110
pF1KB6 RATAVATASRLGPYVLLEPEEGGRAYQALHCPTGTEYTCKVYPVQEALAVLEPYARLPPH
. : : .: :.:::: :: ....:.: .: : .:::. .. : : : :
NP_067 LSHCV---SCIGKYLLLEPLEGDHVFRAVHLHSGEELVCKVFDISCYQESLAPCFCLSAH
60 70 80 90 100 110
120 130 140 150 160 170
pF1KB6 KHVARPTEVLAGTQLLYAFFTRTHGDMHSLVRSRHRIPEPEAAVLFRQMATALAHCHQHG
... . ::.. : :.:: :..:::::.::. ... : ::: :: :.:.:.::::. :
NP_067 SNINQITEIILGETKAYVFFERSYGDMHSFVRTCKKLREEEAARLFYQIASAVAHCHDGG
120 130 140 150 160 170
180 190 200 210 220 230
pF1KB6 LVLRDLKLCRFVFADRERKKLVLENLEDSCVLTGPDDSLWDKHACPAYVGPEILSSRASY
:::::::: .:.: :.:: .. ::.:::. .: : :::: :::.:::::.::::.. .::
NP_067 LVLRDLKLRKFIFKDEERTRVKLESLEDAYILRGDDDSLSDKHGCPAYVSPEILNTSGSY
180 190 200 210 220 230
240 250 260 270 280 290
pF1KB6 SGKAADVWSLGVALFTMLAGHYPFQDSEPVLLFGKIRRGAYALPAGLSAPARCLVRCLLR
:::::::::::: :.:::.:.:::.: :: ::.::::: . .: :: :.::.: .::
NP_067 SGKAADVWSLGVMLYTMLVGRYPFHDIEPSSLFSKIRRGQFNIPETLSPKAKCLIRSILR
240 250 260 270 280 290
300 310 320 330 340 350
pF1KB6 REPAERLTATGILLHPWLRQDPMPLAPTRSHLWEAA-QVVPDGLGLDEAREEEGDREVVL
:::.::::. :: :::. : . .. . :.. :.:::
NP_067 REPSERLTSQEILDHPWFSTD-FSVSNSAYGAKEVSDQLVPDVNMEENLDPFFN
300 310 320 330 340
pF1KB6 YG
>>NP_001269914 (OMIM: 609461) tribbles homolog 1 isoform (206 aa)
initn: 774 init1: 754 opt: 766 Z-score: 418.0 bits: 85.1 E(85289): 1.5e-16
Smith-Waterman score: 766; 57.9% identity (81.0% similar) in 195 aa overlap (144-338:1-194)
120 130 140 150 160 170
pF1KB6 LPPHKHVARPTEVLAGTQLLYAFFTRTHGDMHSLVRSRHRIPEPEAAVLFRQMATALAHC
::: ::::.:. : ::: ::.:...:.:::
NP_001 MHSYVRSRKRLREEEAARLFKQIVSAVAHC
10 20 30
180 190 200 210 220 230
pF1KB6 HQHGLVLRDLKLCRFVFADRERKKLVLENLEDSCVLTGPDDSLWDKHACPAYVGPEILSS
:: ..:: :::: .:::. .:: .: ::.:::. .. : ::.: :::.:::::.::::..
NP_001 HQSAIVLGDLKLRKFVFSTEERTQLRLESLEDTHIMKGEDDALSDKHGCPAYVSPEILNT
40 50 60 70 80 90
240 250 260 270 280 290
pF1KB6 RASYSGKAADVWSLGVALFTMLAGHYPFQDSEPVLLFGKIRRGAYALPAGLSAPARCLVR
..::::::::::::: :.:.:.:.:::.::.: ::.::::: . .: .: ::::.:
NP_001 TGTYSGKAADVWSLGVMLYTLLVGRYPFHDSDPSALFSKIRRGQFCIPEHISPKARCLIR
100 110 120 130 140 150
300 310 320 330 340 350
pF1KB6 CLLRREPAERLTATGILLHPWLRQDPMPLAPTRSHLWEAAQVVPDGLGLDEAREEEGDRE
::::::.::::: ::::::... : . :.. . :.::.
NP_001 SLLRREPSERLTAPEILLHPWFESVLEP-GYIDSEIGTSDQIVPEYQEDSDISSFFC
160 170 180 190 200
pF1KB6 VVLYG
358 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Fri Nov 4 16:20:50 2016 done: Fri Nov 4 16:20:51 2016
Total Scan time: 9.540 Total Display time: 0.040
Function used was FASTA [36.3.4 Apr, 2011]