FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6507, 359 aa 1>>>pF1KB6507 359 - 359 aa - 359 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 4.8303+/-0.000449; mu= 19.6933+/- 0.028 mean_var=71.8357+/-14.523, 0's: 0 Z-trim(109.2): 102 B-trim: 1130 in 2/48 Lambda= 0.151323 statistics sampled from 17228 (17352) to 17228 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.551), E-opt: 0.2 (0.203), width: 16 Scan time: 7.340 The best scores are: opt bits E(85289) NP_002058 (OMIM: 139313) guanine nucleotide-bindin ( 359) 2333 518.9 6.7e-147 NP_002063 (OMIM: 163000,185300,600998) guanine nuc ( 359) 2159 480.9 1.8e-135 NP_004288 (OMIM: 604397) guanine nucleotide-bindin ( 355) 1950 435.3 9.9e-122 XP_016870117 (OMIM: 163000,185300,600998) PREDICTE ( 301) 1827 408.4 1.1e-113 XP_016870830 (OMIM: 604397) PREDICTED: guanine nuc ( 301) 1667 373.5 3.5e-103 XP_011517526 (OMIM: 604397) PREDICTED: guanine nuc ( 237) 1348 303.7 2.7e-82 NP_002059 (OMIM: 139314) guanine nucleotide-bindin ( 374) 1218 275.5 1.3e-73 NP_002060 (OMIM: 139310) guanine nucleotide-bindin ( 354) 1129 256.1 8.9e-68 NP_620073 (OMIM: 139311,615473) guanine nucleotide ( 354) 1128 255.9 1e-67 NP_002061 (OMIM: 139360,192605) guanine nucleotide ( 355) 1126 255.4 1.4e-67 NP_006487 (OMIM: 139370,602483) guanine nucleotide ( 354) 1114 252.8 8.6e-67 NP_001095856 (OMIM: 139395) guanine nucleotide-bin ( 354) 1103 250.4 4.6e-66 NP_066268 (OMIM: 139311,615473) guanine nucleotide ( 354) 1101 250.0 6.2e-66 NP_000163 (OMIM: 139330,610444,616389) guanine nuc ( 350) 1086 246.7 5.9e-65 NP_653082 (OMIM: 139330,610444,616389) guanine nuc ( 350) 1086 246.7 5.9e-65 XP_011539566 (OMIM: 139340,613856) PREDICTED: guan ( 354) 1068 242.8 9.1e-64 NP_005263 (OMIM: 139340,613856) guanine nucleotide ( 354) 1068 242.8 9.1e-64 NP_001159897 (OMIM: 139360,192605) guanine nucleot ( 318) 1029 234.2 3.1e-61 NP_001269548 (OMIM: 139360,192605) guanine nucleot ( 339) 1029 234.2 3.2e-61 NP_001269549 (OMIM: 139360,192605) guanine nucleot ( 339) 1029 234.2 3.2e-61 NP_002064 (OMIM: 139160) guanine nucleotide-bindin ( 355) 1020 232.3 1.3e-60 NP_006563 (OMIM: 604406) guanine nucleotide-bindin ( 377) 1020 232.3 1.4e-60 NP_031379 (OMIM: 604394) guanine nucleotide-bindin ( 381) 978 223.1 7.9e-58 NP_001243343 (OMIM: 139310) guanine nucleotide-bin ( 302) 965 220.2 4.8e-57 NP_001269546 (OMIM: 139360,192605) guanine nucleot ( 303) 961 219.3 8.7e-57 XP_011521305 (OMIM: 139311,615473) PREDICTED: guan ( 312) 943 215.4 1.4e-55 XP_011514426 (OMIM: 139395) PREDICTED: guanine nuc ( 297) 922 210.8 3.1e-54 NP_001269547 (OMIM: 139360,192605) guanine nucleot ( 274) 875 200.5 3.6e-51 NP_892023 (OMIM: 139312,615073) guanine nucleotide ( 458) 801 184.6 3.9e-46 NP_001269354 (OMIM: 604406) guanine nucleotide-bin ( 282) 791 182.2 1.2e-45 NP_001070957 (OMIM: 102200,103580,139320,166350,17 ( 379) 789 181.9 2.1e-45 NP_001248372 (OMIM: 139312,615073) guanine nucleot ( 381) 788 181.7 2.4e-45 NP_001135811 (OMIM: 139312,615073) guanine nucleot ( 381) 788 181.7 2.4e-45 NP_536351 (OMIM: 102200,103580,139320,166350,17480 ( 380) 781 180.1 7e-45 XP_011513590 (OMIM: 604394) PREDICTED: guanine nuc ( 284) 768 177.2 4e-44 NP_001269370 (OMIM: 604394) guanine nucleotide-bin ( 322) 768 177.2 4.4e-44 XP_016867497 (OMIM: 604394) PREDICTED: guanine nuc ( 253) 753 173.9 3.6e-43 XP_016883303 (OMIM: 102200,103580,139320,166350,17 (1022) 748 173.3 2.1e-42 XP_016883302 (OMIM: 102200,103580,139320,166350,17 (1023) 740 171.6 7.1e-42 XP_016883304 (OMIM: 102200,103580,139320,166350,17 ( 347) 704 163.3 7.5e-40 XP_016884275 (OMIM: 139160) PREDICTED: guanine nuc ( 307) 688 159.7 7.7e-39 NP_001269369 (OMIM: 604394) guanine nucleotide-bin ( 305) 648 151.0 3.3e-36 XP_016883307 (OMIM: 102200,103580,139320,166350,17 ( 320) 636 148.4 2.1e-35 XP_016883308 (OMIM: 102200,103580,139320,166350,17 ( 320) 636 148.4 2.1e-35 XP_016883306 (OMIM: 102200,103580,139320,166350,17 ( 320) 636 148.4 2.1e-35 NP_001296769 (OMIM: 102200,103580,139320,166350,17 ( 335) 607 142.1 1.7e-33 NP_001296790 (OMIM: 102200,103580,139320,166350,17 ( 335) 607 142.1 1.7e-33 NP_000507 (OMIM: 102200,103580,139320,166350,17480 ( 394) 607 142.2 1.9e-33 XP_016883309 (OMIM: 102200,103580,139320,166350,17 ( 320) 603 141.2 3.1e-33 XP_016883305 (OMIM: 102200,103580,139320,166350,17 ( 320) 603 141.2 3.1e-33 >>NP_002058 (OMIM: 139313) guanine nucleotide-binding pr (359 aa) initn: 2333 init1: 2333 opt: 2333 Z-score: 2758.3 bits: 518.9 E(85289): 6.7e-147 Smith-Waterman score: 2333; 100.0% identity (100.0% similar) in 359 aa overlap (1-359:1-359) 10 20 30 40 50 60 pF1KB6 MTLESMMACCLSDEVKESKRINAEIEKQLRRDKRDARRELKLLLLGTGESGKSTFIKQMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MTLESMMACCLSDEVKESKRINAEIEKQLRRDKRDARRELKLLLLGTGESGKSTFIKQMR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 IIHGAGYSEEDKRGFTKLVYQNIFTAMQAMIRAMETLKILYKYEQNKANALLIREVDVEK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 IIHGAGYSEEDKRGFTKLVYQNIFTAMQAMIRAMETLKILYKYEQNKANALLIREVDVEK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 VTTFEHQYVSAIKTLWEDPGIQECYDRRREYQLSDSAKYYLTDVDRIATLGYLPTQQDVL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 VTTFEHQYVSAIKTLWEDPGIQECYDRRREYQLSDSAKYYLTDVDRIATLGYLPTQQDVL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 RVRVPTTGIIEYPFDLENIIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 RVRVPTTGIIEYPFDLENIIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 ESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEDKILYSHLVDYFPEFDGPQR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 ESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEDKILYSHLVDYFPEFDGPQR 250 260 270 280 290 300 310 320 330 340 350 pF1KB6 DAQAAREFILKMFVDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQLNLKEYNLV ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 DAQAAREFILKMFVDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQLNLKEYNLV 310 320 330 340 350 >>NP_002063 (OMIM: 163000,185300,600998) guanine nucleot (359 aa) initn: 2159 init1: 2159 opt: 2159 Z-score: 2553.0 bits: 480.9 E(85289): 1.8e-135 Smith-Waterman score: 2159; 90.3% identity (98.3% similar) in 359 aa overlap (1-359:1-359) 10 20 30 40 50 60 pF1KB6 MTLESMMACCLSDEVKESKRINAEIEKQLRRDKRDARRELKLLLLGTGESGKSTFIKQMR :::::.::::::.:.::..::: :::.::::::::::::::::::::::::::::::::: NP_002 MTLESIMACCLSEEAKEARRINDEIERQLRRDKRDARRELKLLLLGTGESGKSTFIKQMR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 IIHGAGYSEEDKRGFTKLVYQNIFTAMQAMIRAMETLKILYKYEQNKANALLIREVDVEK ::::.:::.:::::::::::::::::::::::::.:::: ::::.:::.: :.::::::: NP_002 IIHGSGYSDEDKRGFTKLVYQNIFTAMQAMIRAMDTLKIPYKYEHNKAHAQLVREVDVEK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 VTTFEHQYVSAIKTLWEDPGIQECYDRRREYQLSDSAKYYLTDVDRIATLGYLPTQQDVL :..::. ::.:::.::.:::::::::::::::::::.::::.:.::.: .::::::::: NP_002 VSAFENPYVDAIKSLWNDPGIQECYDRRREYQLSDSTKYYLNDLDRVADPAYLPTQQDVL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 RVRVPTTGIIEYPFDLENIIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLV ::::::::::::::::...::::::::::::::::::::::::::::::::::::::::: NP_002 RVRVPTTGIIEYPFDLQSVIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLV 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 ESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEDKILYSHLVDYFPEFDGPQR ::::::::::::::::::::::::::::::::::::::::.::.::::::::::.::::: NP_002 ESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEEKIMYSHLVDYFPEYDGPQR 250 260 270 280 290 300 310 320 330 340 350 pF1KB6 DAQAAREFILKMFVDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQLNLKEYNLV ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 DAQAAREFILKMFVDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQLNLKEYNLV 310 320 330 340 350 >>NP_004288 (OMIM: 604397) guanine nucleotide-binding pr (355 aa) initn: 1950 init1: 1950 opt: 1950 Z-score: 2306.4 bits: 435.3 E(85289): 9.9e-122 Smith-Waterman score: 1950; 82.3% identity (94.9% similar) in 351 aa overlap (9-359:5-355) 10 20 30 40 50 60 pF1KB6 MTLESMMACCLSDEVKESKRINAEIEKQLRRDKRDARRELKLLLLGTGESGKSTFIKQMR :::: : :::.::.::::.::::::.:::::::::::::::::::::::::: NP_004 MAGCCCLSAEEKESQRISAEIERQLRRDKKDARRELKLLLLGTGESGKSTFIKQMR 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 IIHGAGYSEEDKRGFTKLVYQNIFTAMQAMIRAMETLKILYKYEQNKANALLIREVDVEK ::::.:::.::..:::::::::::::::::::::.::.: : :::: :: .::::.:.: NP_004 IIHGSGYSDEDRKGFTKLVYQNIFTAMQAMIRAMDTLRIQYVCEQNKENAQIIREVEVDK 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 VTTFEHQYVSAIKTLWEDPGIQECYDRRREYQLSDSAKYYLTDVDRIATLGYLPTQQDVL :. . .. : ::: ::.::::::::::::::::::::::::::.::::: ...::::::: NP_004 VSMLSREQVEAIKQLWQDPGIQECYDRRREYQLSDSAKYYLTDIDRIATPSFVPTQQDVL 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB6 RVRVPTTGIIEYPFDLENIIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQVLV :::::::::::::::::::::::::::::::::::::::::.::::.::::::::::::. NP_004 RVRVPTTGIIEYPFDLENIIFRMVDVGGQRSERRKWIHCFESVTSIIFLVALSEYDQVLA 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB6 ESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEDKILYSHLVDYFPEFDGPQR : :::::::::::::.:::::::: :::::::::::::::.::.::::..::::. ::.. NP_004 ECDNENRMEESKALFKTIITYPWFLNSSVILFLNKKDLLEEKIMYSHLISYFPEYTGPKQ 240 250 260 270 280 290 310 320 330 340 350 pF1KB6 DAQAAREFILKMFVDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQLNLKEYNLV :..:::.::::.. : :::..:.:::::::::::.::::::::::::::::::.:.::: NP_004 DVRAARDFILKLYQDQNPDKEKVIYSHFTCATDTDNIRFVFAAVKDTILQLNLREFNLV 300 310 320 330 340 350 >>XP_016870117 (OMIM: 163000,185300,600998) PREDICTED: g (301 aa) initn: 1827 init1: 1827 opt: 1827 Z-score: 2162.3 bits: 408.4 E(85289): 1.1e-113 Smith-Waterman score: 1827; 90.7% identity (98.3% similar) in 301 aa overlap (59-359:1-301) 30 40 50 60 70 80 pF1KB6 LRRDKRDARRELKLLLLGTGESGKSTFIKQMRIIHGAGYSEEDKRGFTKLVYQNIFTAMQ ::::::.:::.::::::::::::::::::: XP_016 MRIIHGSGYSDEDKRGFTKLVYQNIFTAMQ 10 20 30 90 100 110 120 130 140 pF1KB6 AMIRAMETLKILYKYEQNKANALLIREVDVEKVTTFEHQYVSAIKTLWEDPGIQECYDRR ::::::.:::: ::::.:::.: :.::::::::..::. ::.:::.::.::::::::::: XP_016 AMIRAMDTLKIPYKYEHNKAHAQLVREVDVEKVSAFENPYVDAIKSLWNDPGIQECYDRR 40 50 60 70 80 90 150 160 170 180 190 200 pF1KB6 REYQLSDSAKYYLTDVDRIATLGYLPTQQDVLRVRVPTTGIIEYPFDLENIIFRMVDVGG ::::::::.::::.:.::.: .:::::::::::::::::::::::::...::::::::: XP_016 REYQLSDSTKYYLNDLDRVADPAYLPTQQDVLRVRVPTTGIIEYPFDLQSVIFRMVDVGG 100 110 120 130 140 150 210 220 230 240 250 260 pF1KB6 QRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRTIITYPWFQNSS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 QRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRTIITYPWFQNSS 160 170 180 190 200 210 270 280 290 300 310 320 pF1KB6 VILFLNKKDLLEDKILYSHLVDYFPEFDGPQRDAQAAREFILKMFVDLNPDSDKIIYSHF ::::::::::::.::.::::::::::.::::::::::::::::::::::::::::::::: XP_016 VILFLNKKDLLEEKIMYSHLVDYFPEYDGPQRDAQAAREFILKMFVDLNPDSDKIIYSHF 220 230 240 250 260 270 330 340 350 pF1KB6 TCATDTENIRFVFAAVKDTILQLNLKEYNLV ::::::::::::::::::::::::::::::: XP_016 TCATDTENIRFVFAAVKDTILQLNLKEYNLV 280 290 300 >>XP_016870830 (OMIM: 604397) PREDICTED: guanine nucleot (301 aa) initn: 1667 init1: 1667 opt: 1667 Z-score: 1973.5 bits: 373.5 E(85289): 3.5e-103 Smith-Waterman score: 1667; 81.4% identity (94.7% similar) in 301 aa overlap (59-359:1-301) 30 40 50 60 70 80 pF1KB6 LRRDKRDARRELKLLLLGTGESGKSTFIKQMRIIHGAGYSEEDKRGFTKLVYQNIFTAMQ ::::::.:::.::..::::::::::::::: XP_016 MRIIHGSGYSDEDRKGFTKLVYQNIFTAMQ 10 20 30 90 100 110 120 130 140 pF1KB6 AMIRAMETLKILYKYEQNKANALLIREVDVEKVTTFEHQYVSAIKTLWEDPGIQECYDRR ::::::.::.: : :::: :: .::::.:.::. . .. : ::: ::.::::::::::: XP_016 AMIRAMDTLRIQYVCEQNKENAQIIREVEVDKVSMLSREQVEAIKQLWQDPGIQECYDRR 40 50 60 70 80 90 150 160 170 180 190 200 pF1KB6 REYQLSDSAKYYLTDVDRIATLGYLPTQQDVLRVRVPTTGIIEYPFDLENIIFRMVDVGG :::::::::::::::.::::: ...::::::::::::::::::::::::::::::::::: XP_016 REYQLSDSAKYYLTDIDRIATPSFVPTQQDVLRVRVPTTGIIEYPFDLENIIFRMVDVGG 100 110 120 130 140 150 210 220 230 240 250 260 pF1KB6 QRSERRKWIHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRTIITYPWFQNSS :::::::::::::.::::.::::::::::::.: :::::::::::::.:::::::: ::: XP_016 QRSERRKWIHCFESVTSIIFLVALSEYDQVLAECDNENRMEESKALFKTIITYPWFLNSS 160 170 180 190 200 210 270 280 290 300 310 320 pF1KB6 VILFLNKKDLLEDKILYSHLVDYFPEFDGPQRDAQAAREFILKMFVDLNPDSDKIIYSHF ::::::::::::.::.::::..::::. ::..:..:::.::::.. : :::..:.::::: XP_016 VILFLNKKDLLEEKIMYSHLISYFPEYTGPKQDVRAARDFILKLYQDQNPDKEKVIYSHF 220 230 240 250 260 270 330 340 350 pF1KB6 TCATDTENIRFVFAAVKDTILQLNLKEYNLV ::::::.::::::::::::::::::.:.::: XP_016 TCATDTDNIRFVFAAVKDTILQLNLREFNLV 280 290 300 >>XP_011517526 (OMIM: 604397) PREDICTED: guanine nucleot (237 aa) initn: 1348 init1: 1348 opt: 1348 Z-score: 1598.5 bits: 303.7 E(85289): 2.7e-82 Smith-Waterman score: 1348; 84.1% identity (96.1% similar) in 233 aa overlap (127-359:5-237) 100 110 120 130 140 150 pF1KB6 LKILYKYEQNKANALLIREVDVEKVTTFEHQYVSAIKTLWEDPGIQECYDRRREYQLSDS . : ::: ::.::::::::::::::::::: XP_011 MLSREQVEAIKQLWQDPGIQECYDRRREYQLSDS 10 20 30 160 170 180 190 200 210 pF1KB6 AKYYLTDVDRIATLGYLPTQQDVLRVRVPTTGIIEYPFDLENIIFRMVDVGGQRSERRKW :::::::.::::: ...::::::::::::::::::::::::::::::::::::::::::: XP_011 AKYYLTDIDRIATPSFVPTQQDVLRVRVPTTGIIEYPFDLENIIFRMVDVGGQRSERRKW 40 50 60 70 80 90 220 230 240 250 260 270 pF1KB6 IHCFENVTSIMFLVALSEYDQVLVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKK :::::.::::.::::::::::::.: :::::::::::::.:::::::: ::::::::::: XP_011 IHCFESVTSIIFLVALSEYDQVLAECDNENRMEESKALFKTIITYPWFLNSSVILFLNKK 100 110 120 130 140 150 280 290 300 310 320 330 pF1KB6 DLLEDKILYSHLVDYFPEFDGPQRDAQAAREFILKMFVDLNPDSDKIIYSHFTCATDTEN ::::.::.::::..::::. ::..:..:::.::::.. : :::..:.:::::::::::.: XP_011 DLLEEKIMYSHLISYFPEYTGPKQDVRAARDFILKLYQDQNPDKEKVIYSHFTCATDTDN 160 170 180 190 200 210 340 350 pF1KB6 IRFVFAAVKDTILQLNLKEYNLV :::::::::::::::::.:.::: XP_011 IRFVFAAVKDTILQLNLREFNLV 220 230 >>NP_002059 (OMIM: 139314) guanine nucleotide-binding pr (374 aa) initn: 1334 init1: 1218 opt: 1218 Z-score: 1442.5 bits: 275.5 E(85289): 1.3e-73 Smith-Waterman score: 1325; 55.8% identity (80.4% similar) in 362 aa overlap (10-359:13-374) 10 20 30 40 50 pF1KB6 MTLESMMACCLSDEVKESKRINAEIEKQLRRDKRDARRELKLLLLGTGESGKSTFIK ::... : . :.. ::.. : ..:.. : :::::::: :::::::::: NP_002 MARSLTWRCCPWCLTEDEKAAARVDQEINRILLEQKKQDRGELKLLLLGPGESGKSTFIK 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 QMRIIHGAGYSEEDKRGFTKLVYQNIFTAMQAMIRAMETLKILYKYEQNKANALLIREVD :::::::::::::...:: :::::::..:.:::.::: :.: .. ..: .: :. : NP_002 QMRIIHGAGYSEEERKGFRPLVYQNIFVSMRAMIEAMERLQIPFSRPESKHHASLVMSQD 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 VEKVTTFEHQYVSAIKTLWEDPGIQECYDRRREYQLSDSAKYYLTDVDRIATLGYLPTQQ ::::::..:..:.. ::.: ::. ::.::::..: ::: :::. ..::. ::.:: : NP_002 PYKVTTFEKRYAAAMQWLWRDAGIRACYERRREFHLLDSAVYYLSHLERITEEGYVPTAQ 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB6 DVLRVRVPTTGIIEYPFDLENIIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQ :::: :.::::: :: :.... .:.::::::.:::.::::::::: ....:..:::::: NP_002 DVLRSRMPTTGINEYCFSVQKTNLRIVDVGGQKSERKKWIHCFENVIALIYLASLSEYDQ 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB6 VLVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEDKILYSHLVDYFPEFDG : :...::::.:: ::: ::. :::...:::::::: :.::.:: :::. ::: :.: NP_002 CLEENNQENRMKESLALFGTILELPWFKSTSVILFLNKTDILEEKIPTSHLATYFPSFQG 250 260 270 280 290 300 300 310 320 330 340 pF1KB6 PQRDAQAAREFILKMFVDL------NPDSDKI------IYSHFTCATDTENIRFVFAAVK :..::.::..::: :.. . .:...: ..::.::::::.::: :: :. NP_002 PKQDAEAAKRFILDMYTRMYTGCVDGPEGSKKGARSRRLFSHYTCATDTQNIRKVFKDVR 310 320 330 340 350 360 350 pF1KB6 DTILQLNLKEYNLV :..: : : ::. NP_002 DSVLARYLDEINLL 370 >>NP_002060 (OMIM: 139310) guanine nucleotide-binding pr (354 aa) initn: 1103 init1: 824 opt: 1129 Z-score: 1337.8 bits: 256.1 E(85289): 8.9e-68 Smith-Waterman score: 1129; 51.8% identity (76.1% similar) in 355 aa overlap (7-358:1-353) 10 20 30 40 50 60 pF1KB6 MTLESMMACCLSDEVKESKRINAEIEKQLRRDKRDARRELKLLLLGTGESGKSTFIKQMR :.: :: : : . . . :...::.: . : ::.::::::.:::::::..:::. NP_002 MGCTLSAEDKAAVERSKMIDRNLREDGEKAAREVKLLLLGAGESGKSTIVKQMK 10 20 30 40 50 70 80 90 100 110 pF1KB6 IIHGAGYSEEDKRGFTKLVYQNIFTAMQAMIRAMETLKILY--KYEQNKANALLIREVDV ::: ::::::. . . .::.: . .. :.:::: ::: . . . . : :.. . NP_002 IIHEAGYSEEECKQYKAVVYSNTIQSIIAIIRAMGRLKIDFGDSARADDARQLFVLAGAA 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 EKVTTFEHQYVSAIKTLWEDPGIQECYDRRREYQLSDSAKYYLTDVDRIATLGYLPTQQD :. . . ...:: ::.: :.: :..: :::::.::: :::.:.:::: .:.::::: NP_002 EE-GFMTAELAGVIKRLWKDSGVQACFNRSREYQLNDSAAYYLNDLDRIAQPNYIPTQQD 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB6 VLRVRVPTTGIIEYPFDLENIIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQV :::.:: ::::.: : .... :.: :::::::::.:::::::.::.:.: ::::.:: : NP_002 VLRTRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSDYDLV 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB6 LVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEDKILYSHLVDYFPEFDGP :.:... :::.:: :: .: . :: ..:.:::::::::.:.:: : :. .::. : NP_002 LAEDEEMNRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKIKKSPLTICYPEYAGS 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB6 QRDAQAAREFILKMFVDLNPDSD-KIIYSHFTCATDTENIRFVFAAVKDTILQLNLKEYN . .:: .: .: ::: .: : ::.::::::::.:..::: :: :.:.. :::. . NP_002 NTYEEAA-AYIQCQFEDLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKDCG 300 310 320 330 340 350 pF1KB6 LV : NP_002 LF >>NP_620073 (OMIM: 139311,615473) guanine nucleotide-bin (354 aa) initn: 1098 init1: 711 opt: 1128 Z-score: 1336.6 bits: 255.9 E(85289): 1e-67 Smith-Waterman score: 1128; 50.9% identity (75.7% similar) in 350 aa overlap (7-354:1-349) 10 20 30 40 50 60 pF1KB6 MTLESMMACCLSDEVKESKRINAEIEKQLRRDKRDARRELKLLLLGTGESGKSTFIKQMR :.: :: : . . . . :::.:..: .: ...::::::.:::::::..:::. NP_620 MGCTLSAEERAALERSKAIEKNLKEDGISAAKDVKLLLLGAGESGKSTIVKQMK 10 20 30 40 50 70 80 90 100 110 pF1KB6 IIHGAGYSEEDKRGFTKLVYQNIFTAMQAMIRAMETLKILYKYEQNKANALLIREV--DV ::: :.: :: . . .::.: . .. :..:::.:: : : .. ::.: .. .: . NP_620 IIHEDGFSGEDVKQYKPVVYSNTIQSLAAIVRAMDTLGIEYGDKERKADAKMVCDVVSRM 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 EKVTTFEHQYVSAIKTLWEDPGIQECYDRRREYQLSDSAKYYLTDVDRIATLGYLPTQQD : . : . .::. :: : :::::..: :::::.::::::: ..:::.. : ::.:: NP_620 EDTEPFSAELLSAMMRLWGDSGIQECFNRSREYQLNDSAKYYLDSLDRIGAADYQPTEQD 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB6 VLRVRVPTTGIIEYPFDLENIIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQV .::.:: ::::.: : ..:. ::. :::::::::.:::::::.::.:.: :::: :::: NP_620 ILRTRVKTTGIVETHFTFKNLHFRLFDVGGQRSERKKWIHCFEDVTAIIFCVALSGYDQV 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB6 LVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEDKILYSHLVDYFPEFDGP : :... :::.:: :: .: . :: ..:.::::::::..:.:: : :. :::. :: NP_620 LHEDETTNRMHESLKLFDSICNNKWFTDTSIILFLNKKDIFEEKIKKSPLTICFPEYTGP 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB6 QRDAQAAREFILKMFVDLNPDSDKIIYSHFTCATDTENIRFVFAAVKDTILQLNLKEYNL . ..:. .: .. . : .. : ::.: ::::::.::.::: :: :.:. ::. NP_620 SAFTEAV-AYIQAQYESKNKSAHKEIYTHVTCATDTNNIQFVFDAVTDVIIAKNLRGCGL 300 310 320 330 340 350 pF1KB6 V NP_620 Y >>NP_002061 (OMIM: 139360,192605) guanine nucleotide-bin (355 aa) initn: 1065 init1: 817 opt: 1126 Z-score: 1334.2 bits: 255.4 E(85289): 1.4e-67 Smith-Waterman score: 1126; 50.7% identity (75.2% similar) in 355 aa overlap (7-358:1-354) 10 20 30 40 50 60 pF1KB6 MTLESMMACCLSDEVKESKRINAEIEKQLRRDKRDARRELKLLLLGTGESGKSTFIKQMR :.: .: : : . . . :.:.::.: . : ::.::::::.:::::::..:::. NP_002 MGCTVSAEDKAAAERSKMIDKNLREDGEKAAREVKLLLLGAGESGKSTIVKQMK 10 20 30 40 50 70 80 90 100 110 pF1KB6 IIHGAGYSEEDKRGFTKLVYQNIFTAMQAMIRAMETLKILYK--YEQNKANALLIREVDV ::: :::::. : . .::.: . ...:...:: .:.: . . . : :. . NP_002 IIHEDGYSEEECRQYRAVVYSNTIQSIMAIVKAMGNLQIDFADPSRADDARQLFALSCTA 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 EKVTTFEHQYVSAIKTLWEDPGIQECYDRRREYQLSDSAKYYLTDVDRIATLGYLPTQQD :. .. . ..:. :: : :.: :. : :::::.::: :::.:..::: :.::::: NP_002 EEQGVLPDDLSGVIRRLWADHGVQACFGRSREYQLNDSAAYYLNDLERIAQSDYIPTQQD 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB6 VLRVRVPTTGIIEYPFDLENIIFRMVDVGGQRSERRKWIHCFENVTSIMFLVALSEYDQV :::.:: ::::.: : .... :.: :::::::::.:::::::.::.:.: :::: :: : NP_002 VLRTRVKTTGIVETHFTFKDLHFKMFDVGGQRSERKKWIHCFEGVTAIIFCVALSAYDLV 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB6 LVESDNENRMEESKALFRTIITYPWFQNSSVILFLNKKDLLEDKILYSHLVDYFPEFDGP :.:... :::.:: :: .: . :: ..:.:::::::::.:.:: .: :. :::. : NP_002 LAEDEEMNRMHESMKLFDSICNNKWFTDTSIILFLNKKDLFEEKITHSPLTICFPEYTGA 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB6 QRDAQAAREFILKMFVDLNPDSD-KIIYSHFTCATDTENIRFVFAAVKDTILQLNLKEYN .. .:: .: . : ::: .: : ::.::::::::.:..::: :: :.:.. :::. . NP_002 NKYDEAAS-YIQSKFEDLNKRKDTKEIYTHFTCATDTKNVQFVFDAVTDVIIKNNLKDCG 300 310 320 330 340 350 pF1KB6 LV : NP_002 LF 359 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 21:05:25 2016 done: Fri Nov 4 21:05:27 2016 Total Scan time: 7.340 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]