FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6509, 359 aa 1>>>pF1KB6509 359 - 359 aa - 359 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.3340+/-0.000416; mu= 11.5532+/- 0.026 mean_var=117.6814+/-24.103, 0's: 0 Z-trim(115.4): 405 B-trim: 1166 in 1/48 Lambda= 0.118228 statistics sampled from 25270 (25809) to 25270 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.69), E-opt: 0.2 (0.303), width: 16 Scan time: 6.500 The best scores are: opt bits E(85289) XP_006719333 (OMIM: 125255,610048) PREDICTED: deco ( 359) 2376 416.5 4.7e-116 NP_598010 (OMIM: 125255,610048) decorin isoform a ( 359) 2376 416.5 4.7e-116 NP_001911 (OMIM: 125255,610048) decorin isoform a ( 359) 2376 416.5 4.7e-116 XP_016874406 (OMIM: 125255,610048) PREDICTED: deco ( 359) 2376 416.5 4.7e-116 XP_005268750 (OMIM: 125255,610048) PREDICTED: deco ( 359) 2376 416.5 4.7e-116 NP_001702 (OMIM: 300106,301870) biglycan prepropro ( 368) 1281 229.7 8e-60 XP_016885213 (OMIM: 300106,301870) PREDICTED: bigl ( 368) 1281 229.7 8e-60 NP_060150 (OMIM: 603932,607850,608135) asporin iso ( 379) 1236 222.0 1.7e-57 NP_598011 (OMIM: 125255,610048) decorin isoform b ( 250) 1184 213.0 5.7e-55 NP_598012 (OMIM: 125255,610048) decorin isoform c ( 212) 942 171.7 1.3e-42 NP_598013 (OMIM: 125255,610048) decorin isoform d ( 172) 797 146.9 3.2e-35 NP_001180264 (OMIM: 603932,607850,608135) asporin ( 242) 670 125.3 1.4e-28 NP_598014 (OMIM: 125255,610048) decorin isoform e ( 75) 510 97.6 9.4e-21 NP_002716 (OMIM: 601914) prolargin precursor [Homo ( 382) 498 96.2 1.3e-19 NP_958505 (OMIM: 601914) prolargin precursor [Homo ( 382) 498 96.2 1.3e-19 NP_002336 (OMIM: 600616) lumican precursor [Homo s ( 338) 478 92.7 1.3e-18 NP_001184225 (OMIM: 603479) extracellular matrix p ( 643) 454 88.9 3.5e-17 NP_001184224 (OMIM: 603479) extracellular matrix p ( 677) 454 88.9 3.7e-17 NP_001384 (OMIM: 603479) extracellular matrix prot ( 699) 454 88.9 3.7e-17 NP_001017403 (OMIM: 606653) leucine-rich repeat-co ( 967) 434 85.6 5.1e-16 NP_002014 (OMIM: 600245) fibromodulin precursor [H ( 376) 425 83.7 7.3e-16 NP_060960 (OMIM: 606666,615311) leucine-rich repea ( 951) 423 83.7 1.8e-15 NP_071426 (OMIM: 610486) leucine-rich repeat-conta ( 653) 409 81.2 7.3e-15 XP_016867994 (OMIM: 610486) PREDICTED: leucine-ric ( 653) 409 81.2 7.3e-15 XP_011514763 (OMIM: 610486) PREDICTED: leucine-ric ( 653) 409 81.2 7.3e-15 XP_016873560 (OMIM: 608817) PREDICTED: leucine-ric ( 640) 405 80.5 1.2e-14 XP_011518544 (OMIM: 608817) PREDICTED: leucine-ric ( 640) 405 80.5 1.2e-14 XP_016873567 (OMIM: 608817) PREDICTED: leucine-ric ( 640) 405 80.5 1.2e-14 NP_001245348 (OMIM: 608817) leucine-rich repeat-co ( 640) 405 80.5 1.2e-14 XP_011518542 (OMIM: 608817) PREDICTED: leucine-ric ( 640) 405 80.5 1.2e-14 XP_011518545 (OMIM: 608817) PREDICTED: leucine-ric ( 640) 405 80.5 1.2e-14 XP_011518546 (OMIM: 608817) PREDICTED: leucine-ric ( 640) 405 80.5 1.2e-14 XP_011518543 (OMIM: 608817) PREDICTED: leucine-ric ( 640) 405 80.5 1.2e-14 XP_016873568 (OMIM: 608817) PREDICTED: leucine-ric ( 640) 405 80.5 1.2e-14 XP_016873564 (OMIM: 608817) PREDICTED: leucine-ric ( 640) 405 80.5 1.2e-14 XP_016873559 (OMIM: 608817) PREDICTED: leucine-ric ( 640) 405 80.5 1.2e-14 XP_016873566 (OMIM: 608817) PREDICTED: leucine-ric ( 640) 405 80.5 1.2e-14 XP_016873562 (OMIM: 608817) PREDICTED: leucine-ric ( 640) 405 80.5 1.2e-14 XP_016873561 (OMIM: 608817) PREDICTED: leucine-ric ( 640) 405 80.5 1.2e-14 XP_016873565 (OMIM: 608817) PREDICTED: leucine-ric ( 640) 405 80.5 1.2e-14 XP_011518540 (OMIM: 608817) PREDICTED: leucine-ric ( 640) 405 80.5 1.2e-14 NP_065980 (OMIM: 608817) leucine-rich repeat-conta ( 640) 405 80.5 1.2e-14 XP_016873563 (OMIM: 608817) PREDICTED: leucine-ric ( 640) 405 80.5 1.2e-14 XP_011518541 (OMIM: 608817) PREDICTED: leucine-ric ( 640) 405 80.5 1.2e-14 NP_003658 (OMIM: 606667) leucine-rich repeat-conta ( 907) 400 79.8 2.7e-14 NP_001264155 (OMIM: 606667) leucine-rich repeat-co ( 883) 378 76.0 3.6e-13 NP_003053 (OMIM: 603745) slit homolog 3 protein is (1523) 377 76.0 6e-13 NP_001258875 (OMIM: 603745) slit homolog 3 protein (1530) 377 76.0 6.1e-13 NP_056356 (OMIM: 608868) leucine-rich repeats and (1093) 372 75.1 8.5e-13 NP_001004432 (OMIM: 609794) leucine-rich repeat an ( 593) 364 73.5 1.4e-12 >>XP_006719333 (OMIM: 125255,610048) PREDICTED: decorin (359 aa) initn: 2376 init1: 2376 opt: 2376 Z-score: 2204.6 bits: 416.5 E(85289): 4.7e-116 Smith-Waterman score: 2376; 100.0% identity (100.0% similar) in 359 aa overlap (1-359:1-359) 10 20 30 40 50 60 pF1KB6 MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 HLRVVQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHALILVNNKISKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 HLRVVQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHALILVNNKISKV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 SPGAFTPLVKLERLYLSKNQLKELPEKMPKTLQELRAHENEITKVRKVTFNGLNQMIVIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SPGAFTPLVKLERLYLSKNQLKELPEKMPKTLQELRAHENEITKVRKVTFNGLNQMIVIE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 LGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGNKISRVDAAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGNKISRVDAAS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 LKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLH 250 260 270 280 290 300 310 320 330 340 350 pF1KB6 NNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYWEIQPSTFRCVYVRSAIQLGNYK ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYWEIQPSTFRCVYVRSAIQLGNYK 310 320 330 340 350 >>NP_598010 (OMIM: 125255,610048) decorin isoform a prep (359 aa) initn: 2376 init1: 2376 opt: 2376 Z-score: 2204.6 bits: 416.5 E(85289): 4.7e-116 Smith-Waterman score: 2376; 100.0% identity (100.0% similar) in 359 aa overlap (1-359:1-359) 10 20 30 40 50 60 pF1KB6 MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_598 MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 HLRVVQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHALILVNNKISKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_598 HLRVVQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHALILVNNKISKV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 SPGAFTPLVKLERLYLSKNQLKELPEKMPKTLQELRAHENEITKVRKVTFNGLNQMIVIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_598 SPGAFTPLVKLERLYLSKNQLKELPEKMPKTLQELRAHENEITKVRKVTFNGLNQMIVIE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 LGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGNKISRVDAAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_598 LGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGNKISRVDAAS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 LKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_598 LKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLH 250 260 270 280 290 300 310 320 330 340 350 pF1KB6 NNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYWEIQPSTFRCVYVRSAIQLGNYK ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_598 NNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYWEIQPSTFRCVYVRSAIQLGNYK 310 320 330 340 350 >>NP_001911 (OMIM: 125255,610048) decorin isoform a prep (359 aa) initn: 2376 init1: 2376 opt: 2376 Z-score: 2204.6 bits: 416.5 E(85289): 4.7e-116 Smith-Waterman score: 2376; 100.0% identity (100.0% similar) in 359 aa overlap (1-359:1-359) 10 20 30 40 50 60 pF1KB6 MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 HLRVVQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHALILVNNKISKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HLRVVQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHALILVNNKISKV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 SPGAFTPLVKLERLYLSKNQLKELPEKMPKTLQELRAHENEITKVRKVTFNGLNQMIVIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SPGAFTPLVKLERLYLSKNQLKELPEKMPKTLQELRAHENEITKVRKVTFNGLNQMIVIE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 LGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGNKISRVDAAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGNKISRVDAAS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 LKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLH 250 260 270 280 290 300 310 320 330 340 350 pF1KB6 NNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYWEIQPSTFRCVYVRSAIQLGNYK ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYWEIQPSTFRCVYVRSAIQLGNYK 310 320 330 340 350 >>XP_016874406 (OMIM: 125255,610048) PREDICTED: decorin (359 aa) initn: 2376 init1: 2376 opt: 2376 Z-score: 2204.6 bits: 416.5 E(85289): 4.7e-116 Smith-Waterman score: 2376; 100.0% identity (100.0% similar) in 359 aa overlap (1-359:1-359) 10 20 30 40 50 60 pF1KB6 MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 HLRVVQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHALILVNNKISKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HLRVVQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHALILVNNKISKV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 SPGAFTPLVKLERLYLSKNQLKELPEKMPKTLQELRAHENEITKVRKVTFNGLNQMIVIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SPGAFTPLVKLERLYLSKNQLKELPEKMPKTLQELRAHENEITKVRKVTFNGLNQMIVIE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 LGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGNKISRVDAAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGNKISRVDAAS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 LKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLH 250 260 270 280 290 300 310 320 330 340 350 pF1KB6 NNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYWEIQPSTFRCVYVRSAIQLGNYK ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYWEIQPSTFRCVYVRSAIQLGNYK 310 320 330 340 350 >>XP_005268750 (OMIM: 125255,610048) PREDICTED: decorin (359 aa) initn: 2376 init1: 2376 opt: 2376 Z-score: 2204.6 bits: 416.5 E(85289): 4.7e-116 Smith-Waterman score: 2376; 100.0% identity (100.0% similar) in 359 aa overlap (1-359:1-359) 10 20 30 40 50 60 pF1KB6 MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 HLRVVQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHALILVNNKISKV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 HLRVVQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHALILVNNKISKV 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 SPGAFTPLVKLERLYLSKNQLKELPEKMPKTLQELRAHENEITKVRKVTFNGLNQMIVIE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SPGAFTPLVKLERLYLSKNQLKELPEKMPKTLQELRAHENEITKVRKVTFNGLNQMIVIE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 LGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGNKISRVDAAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGNKISRVDAAS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 LKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLH 250 260 270 280 290 300 310 320 330 340 350 pF1KB6 NNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYWEIQPSTFRCVYVRSAIQLGNYK ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 NNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYWEIQPSTFRCVYVRSAIQLGNYK 310 320 330 340 350 >>NP_001702 (OMIM: 300106,301870) biglycan preproprotein (368 aa) initn: 707 init1: 642 opt: 1281 Z-score: 1195.0 bits: 229.7 E(85289): 8e-60 Smith-Waterman score: 1326; 55.8% identity (78.7% similar) in 362 aa overlap (7-359:7-367) 10 20 30 40 50 pF1KB6 MKATIILLLLAQVSWAGPFQQRGLFDFMLED--------EASGIGPE-VPDDRDFEPSLG :. : .: : ::.:::..:: :.: :::: : : . :. . NP_001 MWPLWRLVSLLALSQALPFEQRGFWDFTLDDGPFMMNDEEASGADTSGVLDPDSVTPTYS 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 PVCPFRCQCHLRVVQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHALI .::: :.::::::::::::: .:::.. ::::::::::: :.:.. :::.:..:.::. NP_001 AMCPFGCHCHLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALV 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 LVNNKISKVSPGAFTPLVKLERLYLSKNQLKELPEKMPKTLQELRAHENEITKVRKVTFN ::::::::. ::.:: ::..::.:::.: :.: ..:..: ::: :.:.: :: : .:. NP_001 LVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFS 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB6 GLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGN :: .: ::.: :::..::.: :::.:.: :.:.::.....:.::. :: .:.::::: : NP_001 GLRNMNCIEMGGNPLENSGFEPGAFDGLK-LNYLRISEAKLTGIPKDLPETLNELHLDHN 190 200 210 220 230 240 250 260 270 280 290 pF1KB6 KISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEH ::. .. .: ..: .:::. :.: ..::::. : :::::::::::.:::.:: . NP_001 KIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLARVPSGLPDL 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB6 KYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYWEIQPSTFRCVYVRS : .::::::.:::. :: .:::: : ..:.: :.:.:::.::: :::.::.::::: : NP_001 KLLQVVYLHSNNITKVGVNDFCPMGFGVKRAYYNGISLFNNPVPYWEVQPATFRCVTDRL 300 310 320 330 340 350 pF1KB6 AIQLGNYK :::.:::: NP_001 AIQFGNYKK 360 >>XP_016885213 (OMIM: 300106,301870) PREDICTED: biglycan (368 aa) initn: 707 init1: 642 opt: 1281 Z-score: 1195.0 bits: 229.7 E(85289): 8e-60 Smith-Waterman score: 1326; 55.8% identity (78.7% similar) in 362 aa overlap (7-359:7-367) 10 20 30 40 50 pF1KB6 MKATIILLLLAQVSWAGPFQQRGLFDFMLED--------EASGIGPE-VPDDRDFEPSLG :. : .: : ::.:::..:: :.: :::: : : . :. . XP_016 MWPLWRLVSLLALSQALPFEQRGFWDFTLDDGPFMMNDEEASGADTSGVLDPDSVTPTYS 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 PVCPFRCQCHLRVVQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHALI .::: :.::::::::::::: .:::.. ::::::::::: :.:.. :::.:..:.::. XP_016 AMCPFGCHCHLRVVQCSDLGLKSVPKEISPDTTLLDLQNNDISELRKDDFKGLQHLYALV 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 LVNNKISKVSPGAFTPLVKLERLYLSKNQLKELPEKMPKTLQELRAHENEITKVRKVTFN ::::::::. ::.:: ::..::.:::.: :.: ..:..: ::: :.:.: :: : .:. XP_016 LVNNKISKIHEKAFSPLRKLQKLYISKNHLVEIPPNLPSSLVELRIHDNRIRKVPKGVFS 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB6 GLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGN :: .: ::.: :::..::.: :::.:.: :.:.::.....:.::. :: .:.::::: : XP_016 GLRNMNCIEMGGNPLENSGFEPGAFDGLK-LNYLRISEAKLTGIPKDLPETLNELHLDHN 190 200 210 220 230 240 250 260 270 280 290 pF1KB6 KISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEH ::. .. .: ..: .:::. :.: ..::::. : :::::::::::.:::.:: . XP_016 KIQAIELEDLLRYSKLYRLGLGHNQIRMIENGSLSFLPTLRELHLDNNKLARVPSGLPDL 240 250 260 270 280 290 300 310 320 330 340 350 pF1KB6 KYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYWEIQPSTFRCVYVRS : .::::::.:::. :: .:::: : ..:.: :.:.:::.::: :::.::.::::: : XP_016 KLLQVVYLHSNNITKVGVNDFCPMGFGVKRAYYNGISLFNNPVPYWEVQPATFRCVTDRL 300 310 320 330 340 350 pF1KB6 AIQLGNYK :::.:::: XP_016 AIQFGNYKK 360 >>NP_060150 (OMIM: 603932,607850,608135) asporin isoform (379 aa) initn: 1256 init1: 625 opt: 1236 Z-score: 1153.4 bits: 222.0 E(85289): 1.7e-57 Smith-Waterman score: 1240; 50.7% identity (76.0% similar) in 379 aa overlap (1-358:1-377) 10 20 30 40 pF1KB6 MKATIILLLLAQVSWAGPF---QQRGLFDFMLEDEASGIGPEVPDDRD------------ :: ..::.:: : : :: .. .: ..::.: . . :: : NP_060 MKEYVLLLFLALCS-AKPFFSPSHIALKNMMLKDMEDTDDDDDDDDDDDDDEDNSLFPTR 10 20 30 40 50 50 60 70 80 90 pF1KB6 -----FEP-SLGPVCPFRCQCHLRVVQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDG : : .: :.::: :::. :::.:::::: .:: ..: :: .:::::::: :::.. NP_060 EPRSHFFPFDLFPMCPFGCQCYSRVVHCSDLGLTSVPTNIPFDTRMLDLQNNKIKEIKEN 60 70 80 90 100 110 100 110 120 130 140 150 pF1KB6 DFKNLKNLHALILVNNKISKVSPGAFTPLVKLERLYLSKNQLKELPEKMPKTLQELRAHE :::.: .:..::: :::..:. : :: ::.:::::.:::.:.: ..::.: ::: :: NP_060 DFKGLTSLYGLILNNNKLTKIHPKAFLTTKKLRRLYLSHNQLSEIPLNLPKSLAELRIHE 120 130 140 150 160 170 160 170 180 190 200 210 pF1KB6 NEITKVRKVTFNGLNQMIVIELGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGL :.. :..: ::.:.: . :.:...::: ..::: :::.:. . .::::....::.:.:: NP_060 NKVKKIQKDTFKGMNALHVLEMSANPLDNNGIEPGAFEGVT-VFHIRIAEAKLTSVPKGL 180 190 200 210 220 230 220 230 240 250 260 270 pF1KB6 PPSLTELHLDGNKISRVDAASLKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNN ::.: ::::: :::: :. ..: ..: .:::. :.:. ..:::::: :..::.::.:: NP_060 PPTLLELHLDYNKISTVELEDFKRYKELQRLGLGNNKITDIENGSLANIPRVREIHLENN 240 250 260 270 280 290 280 290 300 310 320 330 pF1KB6 KLTRVPGGLAEHKYIQVVYLHNNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYWEI :: ..:.:: : ::.:...::.:.:. :: .:::: . ::. ::..:::.:::.:::. NP_060 KLKKIPSGLPELKYLQIIFLHSNSIARVGVNDFCPTVPKMKKSLYSAISLFNNPVKYWEM 300 310 320 330 340 350 340 350 pF1KB6 QPSTFRCVYVRSAIQLGNYK ::.::::: : ..::::. NP_060 QPATFRCVLSRMSVQLGNFGM 360 370 >>NP_598011 (OMIM: 125255,610048) decorin isoform b prec (250 aa) initn: 1184 init1: 1184 opt: 1184 Z-score: 1107.9 bits: 213.0 E(85289): 5.7e-55 Smith-Waterman score: 1456; 69.6% identity (69.6% similar) in 359 aa overlap (1-359:1-250) 10 20 30 40 50 60 pF1KB6 MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_598 MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 HLRVVQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHALILVNNKISKV :::::::::: NP_598 HLRVVQCSDL-------------------------------------------------- 70 130 140 150 160 170 180 pF1KB6 SPGAFTPLVKLERLYLSKNQLKELPEKMPKTLQELRAHENEITKVRKVTFNGLNQMIVIE : NP_598 -----------------------------------------------------------E 190 200 210 220 230 240 pF1KB6 LGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGNKISRVDAAS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_598 LGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGNKISRVDAAS 80 90 100 110 120 130 250 260 270 280 290 300 pF1KB6 LKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_598 LKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLH 140 150 160 170 180 190 310 320 330 340 350 pF1KB6 NNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYWEIQPSTFRCVYVRSAIQLGNYK ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_598 NNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYWEIQPSTFRCVYVRSAIQLGNYK 200 210 220 230 240 250 >>NP_598012 (OMIM: 125255,610048) decorin isoform c prec (212 aa) initn: 942 init1: 942 opt: 942 Z-score: 885.7 bits: 171.7 E(85289): 1.3e-42 Smith-Waterman score: 1140; 59.1% identity (59.1% similar) in 359 aa overlap (1-359:1-212) 10 20 30 40 50 60 pF1KB6 MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_598 MKATIILLLLAQVSWAGPFQQRGLFDFMLEDEASGIGPEVPDDRDFEPSLGPVCPFRCQC 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 HLRVVQCSDLGLDKVPKDLPPDTTLLDLQNNKITEIKDGDFKNLKNLHALILVNNKISKV :::::::::::: NP_598 HLRVVQCSDLGL------------------------------------------------ 70 130 140 150 160 170 180 pF1KB6 SPGAFTPLVKLERLYLSKNQLKELPEKMPKTLQELRAHENEITKVRKVTFNGLNQMIVIE NP_598 ------------------------------------------------------------ 190 200 210 220 230 240 pF1KB6 LGTNPLKSSGIENGAFQGMKKLSYIRIADTNITSIPQGLPPSLTELHLDGNKISRVDAAS ::::::::::::::::::::: NP_598 ---------------------------------------PPSLTELHLDGNKISRVDAAS 80 90 250 260 270 280 290 300 pF1KB6 LKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_598 LKGLNNLAKLGLSFNSISAVDNGSLANTPHLRELHLDNNKLTRVPGGLAEHKYIQVVYLH 100 110 120 130 140 150 310 320 330 340 350 pF1KB6 NNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYWEIQPSTFRCVYVRSAIQLGNYK ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_598 NNNISVVGSSDFCPPGHNTKKASYSGVSLFSNPVQYWEIQPSTFRCVYVRSAIQLGNYK 160 170 180 190 200 210 359 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 23:11:24 2016 done: Fri Nov 4 23:11:25 2016 Total Scan time: 6.500 Total Display time: 0.040 Function used was FASTA [36.3.4 Apr, 2011]