FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6510, 384 aa 1>>>pF1KB6510 384 - 384 aa - 384 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.6124+/-0.000718; mu= 15.1719+/- 0.043 mean_var=66.9714+/-13.571, 0's: 0 Z-trim(108.8): 21 B-trim: 34 in 1/50 Lambda= 0.156722 statistics sampled from 10458 (10477) to 10458 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.692), E-opt: 0.2 (0.322), width: 16 Scan time: 3.040 The best scores are: opt bits E(32554) CCDS534.1 NSUN4 gene_id:387338|Hs108|chr1 ( 384) 2594 595.2 3.3e-170 CCDS57996.1 NSUN4 gene_id:387338|Hs108|chr1 ( 335) 2274 522.8 1.8e-148 CCDS2927.1 NSUN3 gene_id:63899|Hs108|chr3 ( 340) 565 136.4 3.7e-32 CCDS58202.1 NOP2 gene_id:4839|Hs108|chr12 ( 628) 262 68.0 2.7e-11 CCDS44811.1 NOP2 gene_id:4839|Hs108|chr12 ( 808) 262 68.0 3.4e-11 CCDS58203.1 NOP2 gene_id:4839|Hs108|chr12 ( 812) 262 68.0 3.4e-11 CCDS58204.1 NOP2 gene_id:4839|Hs108|chr12 ( 845) 262 68.0 3.5e-11 >>CCDS534.1 NSUN4 gene_id:387338|Hs108|chr1 (384 aa) initn: 2594 init1: 2594 opt: 2594 Z-score: 3169.2 bits: 595.2 E(32554): 3.3e-170 Smith-Waterman score: 2594; 100.0% identity (100.0% similar) in 384 aa overlap (1-384:1-384) 10 20 30 40 50 60 pF1KB6 MAALTLRGVRELLKRVDLATVPRRHRYKKKWAATEPKFPAVRLALQNFDMTYSVQFGDLW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 MAALTLRGVRELLKRVDLATVPRRHRYKKKWAATEPKFPAVRLALQNFDMTYSVQFGDLW 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 PSIRVSLLSEQKYGALVNNFAAWDHVSAKLEQLSAKDFVNEAISHWELQSEGGQSAAPSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 PSIRVSLLSEQKYGALVNNFAAWDHVSAKLEQLSAKDFVNEAISHWELQSEGGQSAAPSP 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 ASWACSPNLRCFTFDRGDISRFPPARPGSLGVMEYYLMDAASLLPVLALGLQPGDIVLDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 ASWACSPNLRCFTFDRGDISRFPPARPGSLGVMEYYLMDAASLLPVLALGLQPGDIVLDL 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 CAAPGGKTLALLQTGCCRNLAANDLSPSRIARLQKILHSYVPEEIRDGNQVRVTSWDGRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 CAAPGGKTLALLQTGCCRNLAANDLSPSRIARLQKILHSYVPEEIRDGNQVRVTSWDGRK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 WGELEGDTYDRVLVDVPCTTDRHSLHEEENNIFKRSRKKERQILPVLQVQLLAAGLLATK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 WGELEGDTYDRVLVDVPCTTDRHSLHEEENNIFKRSRKKERQILPVLQVQLLAAGLLATK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 PGGHVVYSTCSLSHLQNEYVVQGAIELLANQYSIQVQVEDLTHFRRVFMDTFCFFSSCQV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 PGGHVVYSTCSLSHLQNEYVVQGAIELLANQYSIQVQVEDLTHFRRVFMDTFCFFSSCQV 310 320 330 340 350 360 370 380 pF1KB6 GELVIPNLMANFGPMYFCKMRRLT :::::::::::::::::::::::: CCDS53 GELVIPNLMANFGPMYFCKMRRLT 370 380 >>CCDS57996.1 NSUN4 gene_id:387338|Hs108|chr1 (335 aa) initn: 2274 init1: 2274 opt: 2274 Z-score: 2779.2 bits: 522.8 E(32554): 1.8e-148 Smith-Waterman score: 2274; 100.0% identity (100.0% similar) in 335 aa overlap (50-384:1-335) 20 30 40 50 60 70 pF1KB6 TVPRRHRYKKKWAATEPKFPAVRLALQNFDMTYSVQFGDLWPSIRVSLLSEQKYGALVNN :::::::::::::::::::::::::::::: CCDS57 MTYSVQFGDLWPSIRVSLLSEQKYGALVNN 10 20 30 80 90 100 110 120 130 pF1KB6 FAAWDHVSAKLEQLSAKDFVNEAISHWELQSEGGQSAAPSPASWACSPNLRCFTFDRGDI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS57 FAAWDHVSAKLEQLSAKDFVNEAISHWELQSEGGQSAAPSPASWACSPNLRCFTFDRGDI 40 50 60 70 80 90 140 150 160 170 180 190 pF1KB6 SRFPPARPGSLGVMEYYLMDAASLLPVLALGLQPGDIVLDLCAAPGGKTLALLQTGCCRN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS57 SRFPPARPGSLGVMEYYLMDAASLLPVLALGLQPGDIVLDLCAAPGGKTLALLQTGCCRN 100 110 120 130 140 150 200 210 220 230 240 250 pF1KB6 LAANDLSPSRIARLQKILHSYVPEEIRDGNQVRVTSWDGRKWGELEGDTYDRVLVDVPCT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS57 LAANDLSPSRIARLQKILHSYVPEEIRDGNQVRVTSWDGRKWGELEGDTYDRVLVDVPCT 160 170 180 190 200 210 260 270 280 290 300 310 pF1KB6 TDRHSLHEEENNIFKRSRKKERQILPVLQVQLLAAGLLATKPGGHVVYSTCSLSHLQNEY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS57 TDRHSLHEEENNIFKRSRKKERQILPVLQVQLLAAGLLATKPGGHVVYSTCSLSHLQNEY 220 230 240 250 260 270 320 330 340 350 360 370 pF1KB6 VVQGAIELLANQYSIQVQVEDLTHFRRVFMDTFCFFSSCQVGELVIPNLMANFGPMYFCK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS57 VVQGAIELLANQYSIQVQVEDLTHFRRVFMDTFCFFSSCQVGELVIPNLMANFGPMYFCK 280 290 300 310 320 330 380 pF1KB6 MRRLT ::::: CCDS57 MRRLT >>CCDS2927.1 NSUN3 gene_id:63899|Hs108|chr3 (340 aa) initn: 534 init1: 206 opt: 565 Z-score: 690.7 bits: 136.4 E(32554): 3.7e-32 Smith-Waterman score: 614; 35.4% identity (64.1% similar) in 345 aa overlap (42-382:19-333) 20 30 40 50 60 70 pF1KB6 LLKRVDLATVPRRHRYKKKWAATEPKFPAVRLALQNFDMTYSVQFGDLWPSIRVSLLSEQ ...:..:. :: ..:: : ..: : : . CCDS29 MLTQLKAKSEGKLAKQICKVVLDHFEKQYSKELGDAWNTVREILTSPS 10 20 30 40 80 90 100 110 120 pF1KB6 --KYGALVNNFAAWDHVSAKLEQLSAKDFVNEAISHWELQSEGGQSAAPSPASWACSPNL .:..:.: : . .:: ::. .. .. :.:. :. .. CCDS29 CWQYAVLLNRF----NYPFELE----KDL---HLKGYHTLSQGSLPNYPK--------SV 50 60 70 80 130 140 150 160 170 180 pF1KB6 RCFTFDRGDISRFPPARPGSLGVMEYYLMDAASLLPVLALGLQPGDIVLDLCAAPGGKTL .:. ..: .:.: : .. .:::..:::::::::: :. :. :::::::::::.. CCDS29 KCY-LSRTP-GRIPSERHQIGNLKKYYLLNAASLLPVLALELRDGEKVLDLCAAPGGKSI 90 100 110 120 130 140 190 200 210 220 230 240 pF1KB6 ALLQTGCCRNLAANDLSPSRIARLQKILHSYVPEEIRDGNQVRVTSWDGRKWGELEGDTY :::: .: : :. . :. :.. :.:..:. . : ..:. :::: :. . . . CCDS29 ALLQCACPGYLHCNEYDSLRLRWLRQTLESFIPQPLI--NVIKVSELDGRKMGDAQPEMF 150 160 170 180 190 200 250 260 270 280 290 300 pF1KB6 DRVLVDVPCTTDRHSLHEEENNIFKRS-RKKERQILPVLQVQLLAAGLLATKPGGHVVYS :.::::.::..:: : ... : : : ..:. ::.::..:: ... : .::: .::: CCDS29 DKVLVDAPCSNDRSWLFSSDSQ--KASCRISQRRNLPLLQIELLRSAIKALRPGGILVYS 210 220 230 240 250 260 310 320 330 340 350 360 pF1KB6 TCSLSHLQNEYVVQGAIELLANQYSIQVQVEDLTHFRRVFMDTFCFFSSCQ-VGELVIPN ::.::. .:. :.. :.: .. .:. . :. . :. : : . : : ::::. CCDS29 TCTLSKAENQDVIS---EILNSHGNIMPM--DIKGIARTCSHDFTFAPTGQECGLLVIPD 270 280 290 300 310 370 380 pF1KB6 LMANFGPMYFCKMRRLT .:::: :... CCDS29 KGKAWGPMYVAKLKKSWSTGKW 320 330 340 >>CCDS58202.1 NOP2 gene_id:4839|Hs108|chr12 (628 aa) initn: 274 init1: 131 opt: 262 Z-score: 316.3 bits: 68.0 E(32554): 2.7e-11 Smith-Waterman score: 274; 33.3% identity (62.8% similar) in 180 aa overlap (155-326:362-529) 130 140 150 160 170 180 pF1KB6 CSPNLRCFTFDRGDISRFPPARPGSLGVMEYYLMDAASLLPVLALGLQPGDIVLDLCAAP :.:. :.:.:::.::. : . .::.: :: CCDS58 DPLGKWSKTGLVVYDSSVPIGATPEYLAGHYMLQGASSMLPVMALAPQEHERILDMCCAP 340 350 360 370 380 390 190 200 210 220 230 240 pF1KB6 GGKTLALLQTGCCRNLA-ANDLSPSRIARLQKILHSYVPEEIRDG-NQVRVTSWDGRKWG :::: . : .. ::: . :. . :: : : ... .. .:::.. CCDS58 GGKTSYMAQLMKNTGVILANDANAERLKSVVGNLH-------RLGVTNTIISHYDGRQFP 400 410 420 430 440 250 260 270 280 290 pF1KB6 ELEGDTYDRVLVDVPCTTDRHSLHEEENNIFKRSRKKERQILPV--LQVQLLAAGL---- .. : .::::.:.::. .. .. . .. : :..:: :: .:: ... CCDS58 KVVGG-FDRVLLDAPCSGT--GVISKDPAV--KTNKDEKDILRCAHLQKELLLSAIDSVN 450 460 470 480 490 300 310 320 330 340 350 pF1KB6 LATKPGGHVVYSTCSLSHLQNEYVVQGAIELLANQYSIQVQVEDLTHFRRVFMDTFCFFS ..: ::..:: :::.. .::.::. :.. CCDS58 ATSKTGGYLVYCTCSITVEENEWVVDYALKKRNVRLVPTGLDFGQEGFTRFRERRFHPSL 500 510 520 530 540 550 >>CCDS44811.1 NOP2 gene_id:4839|Hs108|chr12 (808 aa) initn: 274 init1: 131 opt: 262 Z-score: 314.5 bits: 68.0 E(32554): 3.4e-11 Smith-Waterman score: 274; 33.3% identity (62.8% similar) in 180 aa overlap (155-326:362-529) 130 140 150 160 170 180 pF1KB6 CSPNLRCFTFDRGDISRFPPARPGSLGVMEYYLMDAASLLPVLALGLQPGDIVLDLCAAP :.:. :.:.:::.::. : . .::.: :: CCDS44 DPLGKWSKTGLVVYDSSVPIGATPEYLAGHYMLQGASSMLPVMALAPQEHERILDMCCAP 340 350 360 370 380 390 190 200 210 220 230 240 pF1KB6 GGKTLALLQTGCCRNLA-ANDLSPSRIARLQKILHSYVPEEIRDG-NQVRVTSWDGRKWG :::: . : .. ::: . :. . :: : : ... .. .:::.. CCDS44 GGKTSYMAQLMKNTGVILANDANAERLKSVVGNLH-------RLGVTNTIISHYDGRQFP 400 410 420 430 440 250 260 270 280 290 pF1KB6 ELEGDTYDRVLVDVPCTTDRHSLHEEENNIFKRSRKKERQILPV--LQVQLLAAGL---- .. : .::::.:.::. .. .. . .. : :..:: :: .:: ... CCDS44 KVVGG-FDRVLLDAPCSGT--GVISKDPAV--KTNKDEKDILRCAHLQKELLLSAIDSVN 450 460 470 480 490 300 310 320 330 340 350 pF1KB6 LATKPGGHVVYSTCSLSHLQNEYVVQGAIELLANQYSIQVQVEDLTHFRRVFMDTFCFFS ..: ::..:: :::.. .::.::. :.. CCDS44 ATSKTGGYLVYCTCSITVEENEWVVDYALKKRNVRLVPTGLDFGQEGFTRFRERRFHPSL 500 510 520 530 540 550 >>CCDS58203.1 NOP2 gene_id:4839|Hs108|chr12 (812 aa) initn: 274 init1: 131 opt: 262 Z-score: 314.5 bits: 68.0 E(32554): 3.4e-11 Smith-Waterman score: 274; 33.3% identity (62.8% similar) in 180 aa overlap (155-326:366-533) 130 140 150 160 170 180 pF1KB6 CSPNLRCFTFDRGDISRFPPARPGSLGVMEYYLMDAASLLPVLALGLQPGDIVLDLCAAP :.:. :.:.:::.::. : . .::.: :: CCDS58 DPLGKWSKTGLVVYDSSVPIGATPEYLAGHYMLQGASSMLPVMALAPQEHERILDMCCAP 340 350 360 370 380 390 190 200 210 220 230 240 pF1KB6 GGKTLALLQTGCCRNLA-ANDLSPSRIARLQKILHSYVPEEIRDG-NQVRVTSWDGRKWG :::: . : .. ::: . :. . :: : : ... .. .:::.. CCDS58 GGKTSYMAQLMKNTGVILANDANAERLKSVVGNLH-------RLGVTNTIISHYDGRQFP 400 410 420 430 440 250 260 270 280 290 pF1KB6 ELEGDTYDRVLVDVPCTTDRHSLHEEENNIFKRSRKKERQILPV--LQVQLLAAGL---- .. : .::::.:.::. .. .. . .. : :..:: :: .:: ... CCDS58 KVVGG-FDRVLLDAPCSGT--GVISKDPAV--KTNKDEKDILRCAHLQKELLLSAIDSVN 450 460 470 480 490 500 300 310 320 330 340 350 pF1KB6 LATKPGGHVVYSTCSLSHLQNEYVVQGAIELLANQYSIQVQVEDLTHFRRVFMDTFCFFS ..: ::..:: :::.. .::.::. :.. CCDS58 ATSKTGGYLVYCTCSITVEENEWVVDYALKKRNVRLVPTGLDFGQEGFTRFRERRFHPSL 510 520 530 540 550 560 >>CCDS58204.1 NOP2 gene_id:4839|Hs108|chr12 (845 aa) initn: 270 init1: 131 opt: 262 Z-score: 314.2 bits: 68.0 E(32554): 3.5e-11 Smith-Waterman score: 274; 33.3% identity (62.8% similar) in 180 aa overlap (155-326:399-566) 130 140 150 160 170 180 pF1KB6 CSPNLRCFTFDRGDISRFPPARPGSLGVMEYYLMDAASLLPVLALGLQPGDIVLDLCAAP :.:. :.:.:::.::. : . .::.: :: CCDS58 DPLGKWSKTGLVVYDSSVPIGATPEYLAGHYMLQGASSMLPVMALAPQEHERILDMCCAP 370 380 390 400 410 420 190 200 210 220 230 240 pF1KB6 GGKTLALLQTGCCRNLA-ANDLSPSRIARLQKILHSYVPEEIRDG-NQVRVTSWDGRKWG :::: . : .. ::: . :. . :: : : ... .. .:::.. CCDS58 GGKTSYMAQLMKNTGVILANDANAERLKSVVGNLH-------RLGVTNTIISHYDGRQFP 430 440 450 460 470 480 250 260 270 280 290 pF1KB6 ELEGDTYDRVLVDVPCTTDRHSLHEEENNIFKRSRKKERQILPV--LQVQLLAAGL---- .. : .::::.:.::. .. .. . .. : :..:: :: .:: ... CCDS58 KVVGG-FDRVLLDAPCSGT--GVISKDPAV--KTNKDEKDILRCAHLQKELLLSAIDSVN 490 500 510 520 530 300 310 320 330 340 350 pF1KB6 LATKPGGHVVYSTCSLSHLQNEYVVQGAIELLANQYSIQVQVEDLTHFRRVFMDTFCFFS ..: ::..:: :::.. .::.::. :.. CCDS58 ATSKTGGYLVYCTCSITVEENEWVVDYALKKRNVRLVPTGLDFGQEGFTRFRERRFHPSL 540 550 560 570 580 590 384 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 16:17:31 2016 done: Fri Nov 4 16:17:31 2016 Total Scan time: 3.040 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]