FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6516, 385 aa 1>>>pF1KB6516 385 - 385 aa - 385 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.8664+/-0.00119; mu= 14.9057+/- 0.071 mean_var=159.7018+/-29.145, 0's: 0 Z-trim(107.4): 152 B-trim: 6 in 1/50 Lambda= 0.101489 statistics sampled from 9391 (9556) to 9391 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.665), E-opt: 0.2 (0.294), width: 16 Scan time: 2.230 The best scores are: opt bits E(32554) CCDS53427.1 SELL gene_id:6402|Hs108|chr1 ( 385) 2817 424.9 5.8e-119 CCDS1282.1 SELP gene_id:6403|Hs108|chr1 ( 830) 1229 192.9 9e-49 CCDS1283.1 SELE gene_id:6401|Hs108|chr1 ( 610) 1148 180.8 2.8e-45 >>CCDS53427.1 SELL gene_id:6402|Hs108|chr1 (385 aa) initn: 2817 init1: 2817 opt: 2817 Z-score: 2249.2 bits: 424.9 E(32554): 5.8e-119 Smith-Waterman score: 2817; 100.0% identity (100.0% similar) in 385 aa overlap (1-385:1-385) 10 20 30 40 50 60 pF1KB6 MGCRRTREGPSKAMIFPWKCQSTQRDLWNIFKLWGWTMLCCDFLAHHGTDCWTYHYSEKP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 MGCRRTREGPSKAMIFPWKCQSTQRDLWNIFKLWGWTMLCCDFLAHHGTDCWTYHYSEKP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 MNWQRARRFCRDNYTDLVAIQNKAEIEYLEKTLPFSRSYYWIGIRKIGGIWTWVGTNKSL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 MNWQRARRFCRDNYTDLVAIQNKAEIEYLEKTLPFSRSYYWIGIRKIGGIWTWVGTNKSL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 TEEAENWGDGEPNNKKNKEDCVEIYIKRNKDAGKWNDDACHKLKAALCYTASCQPWSCSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 TEEAENWGDGEPNNKKNKEDCVEIYIKRNKDAGKWNDDACHKLKAALCYTASCQPWSCSG 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 HGECVEIINNYTCNCDVGYYGPQCQFVIQCEPLEAPELGTMDCTHPLGNFSFSSQCAFSC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 HGECVEIINNYTCNCDVGYYGPQCQFVIQCEPLEAPELGTMDCTHPLGNFSFSSQCAFSC 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 SEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 SEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 ICSEGTELIGKKKTICESSGIWSNPSPICQKLDKSFSMIKEGDYNPLFIPVAVMVTAFSG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS53 ICSEGTELIGKKKTICESSGIWSNPSPICQKLDKSFSMIKEGDYNPLFIPVAVMVTAFSG 310 320 330 340 350 360 370 380 pF1KB6 LAFIIWLARRLKKGKKSKRSMNDPY ::::::::::::::::::::::::: CCDS53 LAFIIWLARRLKKGKKSKRSMNDPY 370 380 >>CCDS1282.1 SELP gene_id:6403|Hs108|chr1 (830 aa) initn: 3469 init1: 1225 opt: 1229 Z-score: 989.1 bits: 192.9 E(32554): 9e-49 Smith-Waterman score: 1229; 51.3% identity (74.5% similar) in 310 aa overlap (21-330:11-320) 10 20 30 40 50 60 pF1KB6 MGCRRTREGPSKAMIFPWKCQSTQRDLWNIFKLWGWTMLCCDFLAHHGTDCWTYHYSEKP : :: ...: .: .. : .. .. . :::::: : CCDS12 MANCQIAILYQRFQRVVFGISQLLCFSALISELTNQKEVAAWTYHYSTKA 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 MNWQRARRFCRDNYTDLVAIQNKAEIEYLEKTLPFSRSYYWIGIRKIGGIWTWVGTNKSL ..:. .:..:.. :::::::::: ::.::.:.::. ::::::::: . ::::::.:.: CCDS12 YSWNISRKYCQNRYTDLVAIQNKNEIDYLNKVLPYYSSYYWIGIRKNNKTWTWVGTKKAL 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 TEEAENWGDGEPNNKKNKEDCVEIYIKRNKDAGKWNDDACHKLKAALCYTASCQPWSCSG :.:::::.:.:::::.:.::::::::: . :::::. : : : ::::::::: ::: CCDS12 TNEAENWADNEPNNKRNNEDCVEIYIKSPSAPGKWNDEHCLKKKHALCYTASCQDMSCSK 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB6 HGECVEIINNYTCNCDVGYYGPQCQFVIQCEPLEAPELGTMDCTHPLGNFSFSSQCAFSC .:::.: :.::::.: :.:::.:..: .: :: :. :.:.::::::::.:::.: : CCDS12 QGECLETIGNYTCSCYPGFYGPECEYVRECGELELPQHVLMNCSHPLGNFSFNSQCSFHC 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB6 SEGTNLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTF ..: ...: . : : :.. : : . :: ::. :. : :.: : .:. :.:.: CCDS12 TDGYQVNGPSKLECLASGIWTNKPPQCLAAQCPPLKIPERGNMTCLHSAKAFQHQSSCSF 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB6 ICSEGTELIGKKKTICESSGIWSNPSPICQKLDKSFSMIKEGDYNPLFIPVAVMVTAFSG : :: :.: . . : .::.:. :.:.:. CCDS12 SCEEGFALVGPEVVQCTASGVWTAPAPVCKAVQCQHLEAPSEGTMDCVHPLTAFAYGSSC 300 310 320 330 340 350 >-- initn: 1826 init1: 452 opt: 456 Z-score: 377.4 bits: 79.7 E(32554): 1.1e-14 Smith-Waterman score: 482; 37.1% identity (66.9% similar) in 178 aa overlap (158-332:336-508) 130 140 150 160 170 180 pF1KB6 GDGEPNNKKNKEDCVEIYIKRNKDAGKWNDDACHKLKAALCYTASCQPWSCSGHGECVEI : : : .:. : .::. . :. : :. CCDS12 CTASGVWTAPAPVCKAVQCQHLEAPSEGTMDCVHPL-TAFAYGSSCK-FECQP-GYRVRG 310 320 330 340 350 360 190 200 210 220 230 240 pF1KB6 INNYTCNCDVGYYG---PQCQFVIQCEPLEAPELGTMDCTHPLGNFSFSSQCAFSCSEGT .. : : :... : :. .:.:::::.: :.:::. : :.....:.: :.:: CCDS12 LDMLRC-IDSGHWSAPLPTCE-AISCEPLESPVHGSMDCSPSLRAFQYDTNCSFRCAEGF 370 380 390 400 410 420 250 260 270 280 290 300 pF1KB6 NLTGIEETTCGPFGNWSSPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSE : : . . : .:.:..: :.::..::. : .:. . .:::::...: . :.:.: :.: CCDS12 MLRGADIVRCDNLGQWTAPAPVCQALQCQDLPVPNEARVNCSHPFGAFRYQSVCSFTCNE 430 440 450 460 470 480 310 320 330 340 350 360 pF1KB6 GTELIGKKKTICESSGIWSNPSPICQKLDKSFSMIKEGDYNPLFIPVAVMVTAFSGLAFI : :.: . : ..: :.. : :: . CCDS12 GLLLVGASVLQCLATGNWNSVPPECQAIPCTPLLSPQNGTMTCVQPLGSSSYKSTCQFIC 490 500 510 520 530 540 >-- initn: 576 init1: 373 opt: 414 Z-score: 344.2 bits: 73.5 E(32554): 7.5e-13 Smith-Waterman score: 414; 28.6% identity (54.1% similar) in 266 aa overlap (127-382:560-810) 100 110 120 130 140 150 pF1KB6 RSYYWIGIRKIGGIWTWVGTNKSLTEEAENWGDGEPNNKKNKEDCVEIYIKRNKDAGKWN : :. : . : : :.. : . . CCDS12 SSYKSTCQFICDEGYSLSGPERLDCTRSGRWTDSPPMCEAIK--CPELF------APEQG 530 540 550 560 570 580 160 170 180 190 200 pF1KB6 DDACHKLKAALCYTASCQPWSCSGHGECVEIINNYTCNCDVGYYG---PQCQFV------ . : .. . ..:. .::. .: .: :: :. . : .. : :. . CCDS12 SLDCSDTRGEFNVGSTCH-FSCD-NGFKLEGPNNVECTTS-GRWSATPPTCKGIASLPTP 590 600 610 620 630 210 220 230 240 250 260 pF1KB6 -IQCEPLEAPELGTMDCTHPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWSSPEPT .:: : .: ::: : : :.:.:.. : :.:. : .: : .: : :.:.. :. CCDS12 GVQCPALTTPGQGTMYCRHHPGTFGFNTTCYFGCNAGFTLIGDSTLSCRPSGQWTAVTPA 640 650 660 670 680 690 270 280 290 300 310 320 pF1KB6 CQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGIWSNPS :....: : . ::::. ..::. : :.: : :: : :. .: :. .: ::. CCDS12 CRAVKCSELHVNKPIAMNCSNLWGNFSYGSICSFHCLEGQLLNGSAQTACQENGHWSTTV 700 710 720 730 740 750 330 340 350 360 370 380 pF1KB6 PICQKLDKSFSMIKEGDYNPLFIPVAVMVTAFSGLAFIIWLARRLKKGKKSKRSMNDPY : :: . :.:. . . :: . . : ... : .:... .: .: CCDS12 PTCQAGPLT---IQEA-LTYFGGAVASTIGLIMGGTLLALLRKRFRQKDDGKCPLNPHSH 760 770 780 790 800 810 CCDS12 LGTYGVFTNAAFDPSP 820 830 >>CCDS1283.1 SELE gene_id:6401|Hs108|chr1 (610 aa) initn: 1278 init1: 1092 opt: 1148 Z-score: 926.4 bits: 180.8 E(32554): 2.8e-45 Smith-Waterman score: 1148; 52.7% identity (78.9% similar) in 279 aa overlap (52-330:22-300) 30 40 50 60 70 80 pF1KB6 STQRDLWNIFKLWGWTMLCCDFLAHHGTDCWTYHYSEKPMNWQRARRFCRDNYTDLVAIQ :.:. : . :....: .:.. :: ::::: CCDS12 MIASQFLSALTLVLLIKESGAWSYNTSTEAMTYDEASAYCQQRYTHLVAIQ 10 20 30 40 50 90 100 110 120 130 140 pF1KB6 NKAEIEYLEKTLPFSRSYYWIGIRKIGGIWTWVGTNKSLTEEAENWGDGEPNNKKNKEDC :: :::::.. : .: :::::::::....:.::::.: :::::.::. :::::... ::: CCDS12 NKEEIEYLNSILSYSPSYYWIGIRKVNNVWVWVGTQKPLTEEAKNWAPGEPNNRQKDEDC 60 70 80 90 100 110 150 160 170 180 190 200 pF1KB6 VEIYIKRNKDAGKWNDDACHKLKAALCYTASCQPWSCSGHGECVEIINNYTCNCDVGYYG :::::::.::.: :::. : : : ::::::.: :::::::::: ::::::.:: :. : CCDS12 VEIYIKREKDVGMWNDERCSKKKLALCYTAACTNTSCSGHGECVETINNYTCKCDPGFSG 120 130 140 150 160 170 210 220 230 240 250 260 pF1KB6 PQCQFVIQCEPLEAPELGTMDCTHPLGNFSFSSQCAFSCSEGTNLTGIEETTCGPFGNWS .:. ...: ::.:: :.. :.:::::::..:.:..::..: ...: : :.:: CCDS12 LKCEQIVNCTALESPEHGSLVCSHPLGNFSYNSSCSISCDRGYLPSSMETMQCMSSGEWS 180 190 200 210 220 230 270 280 290 300 310 320 pF1KB6 SPEPTCQVIQCEPLSAPDLGIMNCSHPLASFSFTSACTFICSEGTELIGKKKTICESSGI .: :.:.:..:. .. : :...: . .:: ....::: : :: ::.: .. : ::: CCDS12 APIPACNVVECDAVTNPANGFVECFQNPGSFPWNTTCTFDCEEGFELMGAQSLQCTSSGN 240 250 260 270 280 290 330 340 350 360 370 380 pF1KB6 WSNPSPICQKLDKSFSMIKEGDYNPLFIPVAVMVTAFSGLAFIIWLARRLKKGKKSKRSM :.: .: :. CCDS12 WDNEKPTCKAVTCRAVRQPQNGSVRCSHSPAGEFTFKSSCNFTCEEGFMLQGPAQVECTT 300 310 320 330 340 350 385 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 04:10:35 2016 done: Sat Nov 5 04:10:36 2016 Total Scan time: 2.230 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]