FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6518, 386 aa 1>>>pF1KB6518 386 - 386 aa - 386 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.3434+/-0.000708; mu= 8.4664+/- 0.043 mean_var=128.1293+/-24.792, 0's: 0 Z-trim(114.5): 123 B-trim: 11 in 1/51 Lambda= 0.113305 statistics sampled from 14966 (15100) to 14966 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.783), E-opt: 0.2 (0.464), width: 16 Scan time: 3.340 The best scores are: opt bits E(32554) CCDS12919.1 SYT5 gene_id:6861|Hs108|chr19 ( 386) 2626 439.9 1.9e-123 CCDS74455.1 SYT5 gene_id:6861|Hs108|chr19 ( 382) 2011 339.3 3.4e-93 CCDS1427.1 SYT2 gene_id:127833|Hs108|chr1 ( 419) 1614 274.4 1.3e-73 CCDS76582.1 SYT1 gene_id:6857|Hs108|chr12 ( 419) 1593 271.0 1.4e-72 CCDS9017.1 SYT1 gene_id:6857|Hs108|chr12 ( 422) 1587 270.0 2.7e-72 CCDS871.1 SYT6 gene_id:148281|Hs108|chr1 ( 425) 972 169.5 5e-42 CCDS7778.1 SYT9 gene_id:143425|Hs108|chr11 ( 491) 940 164.3 2.1e-40 CCDS8732.1 SYT10 gene_id:341359|Hs108|chr12 ( 523) 933 163.2 5e-40 CCDS12798.1 SYT3 gene_id:84258|Hs108|chr19 ( 590) 908 159.1 9.3e-39 CCDS31577.1 SYT7 gene_id:9066|Hs108|chr11 ( 403) 894 156.7 3.3e-38 CCDS73298.1 SYT7 gene_id:9066|Hs108|chr11 ( 447) 894 156.8 3.6e-38 CCDS58139.1 SYT7 gene_id:9066|Hs108|chr11 ( 478) 894 156.8 3.8e-38 CCDS7726.2 SYT8 gene_id:90019|Hs108|chr11 ( 401) 835 147.1 2.6e-35 CCDS1122.1 SYT11 gene_id:23208|Hs108|chr1 ( 431) 797 140.9 2.1e-33 CCDS11922.1 SYT4 gene_id:6860|Hs108|chr18 ( 425) 757 134.4 1.9e-31 CCDS81952.1 SYT17 gene_id:51760|Hs108|chr16 ( 413) 701 125.2 1.1e-28 CCDS76835.1 SYT17 gene_id:51760|Hs108|chr16 ( 470) 701 125.2 1.2e-28 CCDS10575.1 SYT17 gene_id:51760|Hs108|chr16 ( 474) 701 125.2 1.2e-28 CCDS73103.1 SYT15 gene_id:83849|Hs108|chr10 ( 421) 582 105.8 7.8e-23 CCDS8154.1 SYT12 gene_id:91683|Hs108|chr11 ( 421) 580 105.4 9.7e-23 CCDS31470.1 SYT13 gene_id:57586|Hs108|chr11 ( 426) 497 91.9 1.2e-18 CCDS73104.1 SYT15 gene_id:83849|Hs108|chr10 ( 390) 479 88.9 8.5e-18 CCDS73934.1 DOC2B gene_id:8447|Hs108|chr17 ( 412) 440 82.5 7.4e-16 CCDS10666.1 DOC2A gene_id:8448|Hs108|chr16 ( 400) 340 66.2 6e-11 >>CCDS12919.1 SYT5 gene_id:6861|Hs108|chr19 (386 aa) initn: 2626 init1: 2626 opt: 2626 Z-score: 2329.8 bits: 439.9 E(32554): 1.9e-123 Smith-Waterman score: 2626; 100.0% identity (100.0% similar) in 386 aa overlap (1-386:1-386) 10 20 30 40 50 60 pF1KB6 MFPEPPTPGPPSPDTPPDSSRISHGPVPPWALATIVLVSGLLIFSCCFCLYRKSCRRRTG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 MFPEPPTPGPPSPDTPPDSSRISHGPVPPWALATIVLVSGLLIFSCCFCLYRKSCRRRTG 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 KKSQAQAQVHLQEVKGLGQSYIDKVQPEVEELEPAPSGPGQQVADKHELGRLQYSLDYDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 KKSQAQAQVHLQEVKGLGQSYIDKVQPEVEELEPAPSGPGQQVADKHELGRLQYSLDYDF 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 QSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDKRRRYETKVHRQTLNPHFGETFAFK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 QSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDKRRRYETKVHRQTLNPHFGETFAFK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 VPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVDLGRPVQAWRELQAAPREEQEKL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 VPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVDLGRPVQAWRELQAAPREEQEKL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 GDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKKN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 GDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKKN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 TLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGAAAGGAGLRHWADM :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS12 TLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGAAAGGAGLRHWADM 310 320 330 340 350 360 370 380 pF1KB6 LANPRRPIAQWHSLRPPDRVRLLPAP :::::::::::::::::::::::::: CCDS12 LANPRRPIAQWHSLRPPDRVRLLPAP 370 380 >>CCDS74455.1 SYT5 gene_id:6861|Hs108|chr19 (382 aa) initn: 1046 init1: 1025 opt: 2011 Z-score: 1786.5 bits: 339.3 E(32554): 3.4e-93 Smith-Waterman score: 2011; 83.8% identity (88.6% similar) in 377 aa overlap (17-386:7-382) 10 20 30 40 50 pF1KB6 MFPEPPTPGPPSPDTPPDSSRI-SHGPVPPWALATIVLVSGLLIFS----CCFCLYRKSC : :.:. .. : :. : ..: : . :: ::. CCDS74 MTRGGCPVSARLFAQRPHGSWSSLLCVGLKGRLGWEWGTRVLECLCRKDS 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 RRRT--GKKSQAQAQVHLQEVKGLGQSYIDKVQPEVEELEPAPSGPGQQVADKHELGRLQ : ... : .. . .. : .::::::::::::::::::::::::::::: CCDS74 RTPPPCSRSPQPRGLHRPTRLPTPVASATAQVQPEVEELEPAPSGPGQQVADKHELGRLQ 60 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 YSLDYDFQSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDKRRRYETKVHRQTLNPHF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 YSLDYDFQSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDKRRRYETKVHRQTLNPHF 120 130 140 150 160 170 180 190 200 210 220 230 pF1KB6 GETFAFKVPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVDLGRPVQAWRELQAAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 GETFAFKVPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVDLGRPVQAWRELQAAP 180 190 200 210 220 230 240 250 260 270 280 290 pF1KB6 REEQEKLGDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKK ::: :::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 REE-EKLGDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKK 240 250 260 270 280 300 310 320 330 340 350 pF1KB6 KTTIKKNTLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGAAAGGAG :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS74 KTTIKKNTLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGAAAGGAG 290 300 310 320 330 340 360 370 380 pF1KB6 LRHWADMLANPRRPIAQWHSLRPPDRVRLLPAP ::::::::::::::::::::::::::::::::: CCDS74 LRHWADMLANPRRPIAQWHSLRPPDRVRLLPAP 350 360 370 380 >>CCDS1427.1 SYT2 gene_id:127833|Hs108|chr1 (419 aa) initn: 1843 init1: 1436 opt: 1614 Z-score: 1435.2 bits: 274.4 E(32554): 1.3e-73 Smith-Waterman score: 1614; 62.5% identity (87.2% similar) in 368 aa overlap (20-383:53-414) 10 20 30 40 pF1KB6 MFPEPPTPGPPSPDTPPDSSRISHGPVPPWALATIVLVSGLLIFSCCFC ..:.. :.::::: .:..:.:::...:::: CCDS14 PIGPVDNSTESGGAGESQEDMFAKLKEKLFNEINKIPLPPWALIAIAVVAGLLLLTCCFC 30 40 50 60 70 80 50 60 70 80 90 100 pF1KB6 LYRKSC-RRRTGKKSQAQAQ---VHLQEVKGLGQSYIDKVQPEVEELEPAPSGPGQQVAD . .: : ... .:: ..... ......:: ::. : .. . : : : :.. . CCDS14 ICKKCCCKKKKNKKEKGKGMKNAMNMKDMKG-GQDD-DDAETGLTEGE----GEGEEEKE 90 100 110 120 130 110 120 130 140 150 160 pF1KB6 KHELGRLQYSLDYDFQSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDKRRRYETKVH ..::.::.:::::::..:: ::.::: : :::.::.:::::.:.:::::...:::::: CCDS14 PENLGKLQFSLDYDFQANQLTVGVLQAAELPALDMGGTSDPYVKVFLLPDKKKKYETKVH 140 150 160 170 180 190 170 180 190 200 210 220 pF1KB6 RQTLNPHFGETFAFKVPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVPMSSVDLGRPVQA :.:::: :.:::.::::: ::::..::::.:::::::..: ::::.:::..::::.:.. CCDS14 RKTLNPAFNETFTFKVPYQELGGKTLVMAIYDFDRFSKHDIIGEVKVPMNTVDLGQPIEE 200 210 220 230 240 250 230 240 250 260 270 280 pF1KB6 WRELQAAPREEQEKLGDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQ ::.::.. .:: ::::::: ::::::::::::: .::::::::::::::::::::.::.: CCDS14 WRDLQGGEKEEPEKLGDICTSLRYVPTAGKLTVCILEAKNLKKMDVGGLSDPYVKIHLMQ 260 270 280 290 300 310 290 300 310 320 330 340 pF1KB6 GGKKVRKKKTTIKKNTLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGRVAV .::...:::::.::.:::::.::.::::.: .:.::::: .:::::::::::::::.. : CCDS14 NGKRLKKKKTTVKKKTLNPYFNESFSFEIPFEQIQKVQVVVTVLDYDKLGKNEAIGKIFV 320 330 340 350 360 370 350 360 370 380 pF1KB6 GAAAGGAGLRHWADMLANPRRPIAQWHSLRPPDRVRLLPAP :. : :. ::::.::::::::::::::::.: ..: : CCDS14 GSNATGTELRHWSDMLANPRRPIAQWHSLKPEEEVDALLGKNK 380 390 400 410 >>CCDS76582.1 SYT1 gene_id:6857|Hs108|chr12 (419 aa) initn: 1896 init1: 1422 opt: 1593 Z-score: 1416.7 bits: 271.0 E(32554): 1.4e-72 Smith-Waterman score: 1593; 59.9% identity (83.2% similar) in 387 aa overlap (4-380:28-411) 10 20 30 pF1KB6 MFPEPPTPGPPSPDTPPD-----SSRISHGPVPPWA :: .:: . :. ... . :.:::: CCDS76 MVSESHHEALAAPPVTTVATVLPSNATEPASPGEGKEDAFSKLKEKFMNELHKIPLPPWA 10 20 30 40 50 60 40 50 60 70 80 pF1KB6 LATIVLVSGLLIFSCCFCLYRKSC-----RRRTGKKSQAQAQVHLQEVKGLGQSYIDKVQ : .:..:. ::...::::. .: : .. ::.. .. .....:: ::... : : CCDS76 LIAIAIVAVLLVLTCCFCICKK-CLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKD--Q 70 80 90 100 110 90 100 110 120 130 140 pF1KB6 PEVEELEPAPSGPGQQVADKHELGRLQYSLDYDFQSGQLLVGILQAMGLAALDLGGSSDP . : . . .. ....::.::::::::::..::::::.:: : :::.::.::: CCDS76 DDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSDP 120 130 140 150 160 170 150 160 170 180 190 200 pF1KB6 YVRVYLLPDKRRRYETKVHRQTLNPHFGETFAFKVPYVELGGRVLVMAVYDFDRFSRNDA ::.:.:::::....::::::.:::: :.: :.::::: ::::..::::::::::::..: CCDS76 YVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHDI 180 190 200 210 220 230 210 220 230 240 250 260 pF1KB6 IGEVRVPMSSVDLGRPVQAWRELQAAPREEQEKLGDICFSLRYVPTAGKLTVIVLEAKNL ::: .:::..::.:. .. ::.::.: .::::::::::::::::::::::::..:::::: CCDS76 IGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKNL 240 250 260 270 280 290 270 280 290 300 310 320 pF1KB6 KKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKKNTLNPYYNEAFSFEVPCDQVQKVQVEL ::::::::::::::.::.:.::...:::::::::::::::::.:::::: .:.::::: . CCDS76 KKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVVV 300 310 320 330 340 350 330 340 350 360 370 380 pF1KB6 TVLDYDKLGKNEAIGRVAVGAAAGGAGLRHWADMLANPRRPIAQWHSLRPPDRVRLLPAP :::::::.:::.:::.: :: . :: ::::.::::::::::::::.:. ..: CCDS76 TVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLAV 360 370 380 390 400 410 CCDS76 KK >>CCDS9017.1 SYT1 gene_id:6857|Hs108|chr12 (422 aa) initn: 1896 init1: 1422 opt: 1587 Z-score: 1411.3 bits: 270.0 E(32554): 2.7e-72 Smith-Waterman score: 1596; 59.8% identity (83.0% similar) in 388 aa overlap (4-380:28-414) 10 20 30 pF1KB6 MFPEPPTPGPPSPDTPPD-----SSRISHGPVPPWA :: .:: . :. ... . :.:::: CCDS90 MVSESHHEALAAPPVTTVATVLPSNATEPASPGEGKEDAFSKLKEKFMNELHKIPLPPWA 10 20 30 40 50 60 40 50 60 70 80 pF1KB6 LATIVLVSGLLIFSCCFCLYRKSC-----RRRTGKKSQAQAQVHLQEVKGLGQSYIDKVQ : .:..:. ::...::::. .: : .. ::.. .. .....:: ::... :.. CCDS90 LIAIAIVAVLLVLTCCFCICKK-CLFKKKNKKKGKEKGGKNAINMKDVKDLGKTMKDQAL 70 80 90 100 110 90 100 110 120 130 140 pF1KB6 PEVEELEPAPSGPGQQVADKHE-LGRLQYSLDYDFQSGQLLVGILQAMGLAALDLGGSSD . . .: .. ..: ::.::::::::::..::::::.:: : :::.::.:: CCDS90 KDDDAETGLTDGEEKEEPKEEEKLGKLQYSLDYDFQNNQLLVGIIQAAELPALDMGGTSD 120 130 140 150 160 170 150 160 170 180 190 200 pF1KB6 PYVRVYLLPDKRRRYETKVHRQTLNPHFGETFAFKVPYVELGGRVLVMAVYDFDRFSRND :::.:.:::::....::::::.:::: :.: :.::::: ::::..::::::::::::..: CCDS90 PYVKVFLLPDKKKKFETKVHRKTLNPVFNEQFTFKVPYSELGGKTLVMAVYDFDRFSKHD 180 190 200 210 220 230 210 220 230 240 250 260 pF1KB6 AIGEVRVPMSSVDLGRPVQAWRELQAAPREEQEKLGDICFSLRYVPTAGKLTVIVLEAKN ::: .:::..::.:. .. ::.::.: .::::::::::::::::::::::::..::::: CCDS90 IIGEFKVPMNTVDFGHVTEEWRDLQSAEKEEQEKLGDICFSLRYVPTAGKLTVVILEAKN 240 250 260 270 280 290 270 280 290 300 310 320 pF1KB6 LKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKKNTLNPYYNEAFSFEVPCDQVQKVQVE :::::::::::::::.::.:.::...:::::::::::::::::.:::::: .:.::::: CCDS90 LKKMDVGGLSDPYVKIHLMQNGKRLKKKKTTIKKNTLNPYYNESFSFEVPFEQIQKVQVV 300 310 320 330 340 350 330 340 350 360 370 380 pF1KB6 LTVLDYDKLGKNEAIGRVAVGAAAGGAGLRHWADMLANPRRPIAQWHSLRPPDRVRLLPA .:::::::.:::.:::.: :: . :: ::::.::::::::::::::.:. ..: CCDS90 VTVLDYDKIGKNDAIGKVFVGYNSTGAELRHWSDMLANPRRPIAQWHTLQVEEEVDAMLA 360 370 380 390 400 410 pF1KB6 P CCDS90 VKK 420 >>CCDS871.1 SYT6 gene_id:148281|Hs108|chr1 (425 aa) initn: 921 init1: 541 opt: 972 Z-score: 867.9 bits: 169.5 E(32554): 5e-42 Smith-Waterman score: 972; 46.5% identity (72.8% similar) in 331 aa overlap (54-374:83-411) 30 40 50 60 70 pF1KB6 HGPVPPWALATIVLVSGLLIFSCCFCLYRKSCRRRTGKKSQAQAQVHLQEVKGLGQ---- : :.:. : . :.:.. : .. CCDS87 SPDIPAEVQMSVKEHIMRHTRLQRQTTEPASSTRHTSFKRHLPRQMHVSSVDYGNELPPA 60 70 80 90 100 110 80 90 100 110 120 130 pF1KB6 ----SYIDKVQPEVEELEPAPSGPGQQVADKHELGRLQYSLDYDFQSGQLLVGILQAMGL . : ...::. . . . . ... : : :....:: ::... :.: ::.:. : CCDS87 AEQPTSIGRIKPELYKQKSVDGEDAKSEATKS-CGKINFSLRYDYETETLIVRILKAFDL 120 130 140 150 160 170 140 150 160 170 180 190 pF1KB6 AALDLGGSSDPYVRVYLLPDKRRRYETKVHRQTLNPHFGETFAFKVPYVELGGRVLVMAV : :. :::::::..:::::.. . .:.:::.:::: : :.: : ::: ::. : : ..: CCDS87 PAKDFCGSSDPYVKIYLLPDRKCKLQTRVHRKTLNPTFDENFHFPVPYEELADRKLHLSV 180 190 200 210 220 230 200 210 220 230 240 250 pF1KB6 YDFDRFSRNDAIGEVRVP--MSSVDLGRPVQAWRELQAAPREEQEKLGDICFSLRYVPTA .:::::::.: :::: . . . ::.: .. :...: : : . ::.: ::: :.::: CCDS87 FDFDRFSRHDMIGEVILDNLFEASDLSRETSIWKDIQYATSESVD-LGEIMFSLCYLPTA 240 250 260 270 280 290 260 270 280 290 300 310 pF1KB6 GKLTVIVLEAKNLKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKKNTLNPYYNEAFSFE :.::. :.. .::: ::. : ::::::: :: :....::::::::::::: ::::. :. CCDS87 GRLTLTVIKCRNLKAMDITGYSDPYVKVSLLCDGRRLKKKKTTIKKNTLNPVYNEAIIFD 300 310 320 330 340 350 320 330 340 350 360 370 pF1KB6 VPCDQVQKVQVELTVLDYDKLGKNEAIGRVAVGAAAGGAGLRHWADMLANPRRPIAQWHS .: .....:.. ..:.:::..:.:: :: :: .: : : :: .::: ::.:::.::: CCDS87 IPPENMDQVSLLISVMDYDRVGHNEIIGVCRVGITAEGLGRDHWNEMLAYPRKPIAHWHS 360 370 380 390 400 410 380 pF1KB6 LRPPDRVRLLPAP : CCDS87 LVEVKKSFKEGNPRL 420 >>CCDS7778.1 SYT9 gene_id:143425|Hs108|chr11 (491 aa) initn: 915 init1: 518 opt: 940 Z-score: 838.7 bits: 164.3 E(32554): 2.1e-40 Smith-Waterman score: 940; 40.1% identity (69.9% similar) in 382 aa overlap (2-374:115-487) 10 20 30 pF1KB6 MFPEPPTPGPPSPDTPPDSSRISH-GPVPPW : .:::: : : : .::: .: : CCDS77 RGLPSGSKDNNQEPLNYMDTETNEQENSEDFLDPPTPCPDS------SMKISHTSPDIPL 90 100 110 120 130 40 50 60 70 80 pF1KB6 ALATIVL---VSGLLIFSCCFCLYRKSCRRRTGKK--SQAQAQVHLQEVKGLGQ-SYIDK . : . . :. . . .: :. . .. . .. . ..:... : . : . CCDS77 STQTGIQENCAHGVRV-QRQVTEPTSSARHNSIRRQLNLSNPDFNIQQLQKQEQLTGIGR 140 150 160 170 180 190 90 100 110 120 130 140 pF1KB6 VQPEVEELEPAPSGPGQQVADKHELGRLQYSLDYDFQSGQLLVGILQAMGLAALDLGGSS ..::. . . . :.. .... :.:.. : :: . ::.: : .:..: : :..:.: CCDS77 IKPELYKQRSLDNDDGRR-SNSKACGKLNFILKYDCDLEQLIVKIHKAVNLPAKDFSGTS 200 210 220 230 240 250 150 160 170 180 190 200 pF1KB6 DPYVRVYLLPDKRRRYETKVHRQTLNPHFGETFAFKVPYVELGGRVLVMAVYDFDRFSRN ::::..:::::.. ...:::::.:::: : :.: : ::: .: .: : ..:::::::::. CCDS77 DPYVKIYLLPDRKTKHQTKVHRKTLNPVFDEVFLFPVPYNDLEARKLHFSVYDFDRFSRH 260 270 280 290 300 310 210 220 230 240 250 260 pF1KB6 DAIGEVRVP--MSSVDLGRPVQAWRELQAAPREEQEKLGDICFSLRYVPTAGKLTVIVLE : ::.: : .. .:. : :.... . .. . ::.. ::: :.::::.::. ... CCDS77 DLIGQVVVDHFLDLADFPRECILWKDIEYVTNDNVD-LGELMFSLCYLPTAGRLTITIIK 320 330 340 350 360 370 270 280 290 300 310 320 pF1KB6 AKNLKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKKNTLNPYYNEAFSFEVPCDQVQKV :.::: ::. : ::::::: :. :....:.::. :.::::: ::::. :.:: ...... CCDS77 ARNLKAMDITGASDPYVKVSLMCDGRRLKKRKTSTKRNTLNPVYNEAIVFDVPPENIDQI 380 390 400 410 420 430 330 340 350 360 370 380 pF1KB6 QVELTVLDYDKLGKNEAIGRVAVGAAAGGAGLRHWADMLANPRRPIAQWHSLRPPDRVRL .. ..:.:::..:.:: :: :: : : ::..::. ::.:::.:::: CCDS77 HLSIAVMDYDRVGHNEIIGVCQVGNEAERLGRDHWSEMLSYPRKPIAHWHSLVEKR 440 450 460 470 480 490 pF1KB6 LPAP >>CCDS8732.1 SYT10 gene_id:341359|Hs108|chr12 (523 aa) initn: 874 init1: 496 opt: 933 Z-score: 832.1 bits: 163.2 E(32554): 5e-40 Smith-Waterman score: 933; 46.4% identity (75.2% similar) in 302 aa overlap (75-374:199-498) 50 60 70 80 90 100 pF1KB6 SCCFCLYRKSCRRRTGKKSQAQAQVHLQEVKGLGQSYIDKVQPEVEELEPAPSGPGQQVA .: . : ...::. . . . : :.: CCDS87 TRHSSFRRHLPRQMQVSSVDFSMGTEPVLQRGETTTSIGRIKPELYKQKSVDS-EGNQNE 170 180 190 200 210 220 110 120 130 140 150 160 pF1KB6 DKHELGRLQYSLDYDFQSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDKRRRYETKV : . :.:...:.::... :.: :..:. : : :. :.:::::..:::::......:.: CCDS87 DVKICGKLNFTLQYDYENELLVVKIIKALDLPAKDFTGTSDPYVKMYLLPDRKKKFQTRV 230 240 250 260 270 280 170 180 190 200 210 220 pF1KB6 HRQTLNPHFGETFAFKVPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVP--MSSVDLGRP ::.:::: : ::: : : : .:..: : ..:::::::::.: :::: . . ::.: CCDS87 HRKTLNPLFDETFQFPVAYDQLSNRKLHFSVYDFDRFSRHDMIGEVILDNLFEVSDLSRE 290 300 310 320 330 340 230 240 250 260 270 280 pF1KB6 VQAWRELQAAPREEQEKLGDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKVH . .:.... : : . ::.: ::: :.::::..:. :.. .::: ::. : ::::::: CCDS87 ATVWKDIHCATTESID-LGEIMFSLCYLPTAGRMTLTVIKCRNLKAMDITGSSDPYVKVS 350 360 370 380 390 400 290 300 310 320 330 340 pF1KB6 LLQGGKKVRKKKTTIKKNTLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIGR :. :....:.::: ::::::: ::::. :..: ..:..:.. ..:.:::..:.::.:: CCDS87 LMCEGRRLKKRKTTTKKNTLNPVYNEAIIFDIPPENVDQVSLSIAVMDYDRVGHNEVIGV 410 420 430 440 450 460 350 360 370 380 pF1KB6 VAVGAAAGGAGLRHWADMLANPRRPIAQWHSLRPPDRVRLLPAP .: : : : :: .::: :.::..:: : CCDS87 CRTGLDAEGLGRDHWNEMLAYHRKPITHWHPLLELPGRATSFDSQGSCPSPKPPSTP 470 480 490 500 510 520 >>CCDS12798.1 SYT3 gene_id:84258|Hs108|chr19 (590 aa) initn: 1005 init1: 399 opt: 908 Z-score: 809.3 bits: 159.1 E(32554): 9.3e-39 Smith-Waterman score: 908; 47.7% identity (75.0% similar) in 304 aa overlap (82-374:267-567) 60 70 80 90 100 pF1KB6 RKSCRRRTGKKSQAQAQVHLQEVKGLGQSYIDKVQPEVEE-LEP----APSGPGQ-QVAD : ...::. . : . .:::. ... CCDS12 TLTSQPDPSSEERPPALPLPLPGGEEKAKLIGQIKPELYQGTGPGGRRSGGGPGSGEAGT 240 250 260 270 280 290 110 120 130 140 150 160 pF1KB6 KHELGRLQYSLDYDFQSGQLLVGILQAMGLAALDLGGSSDPYVRVYLLPDKRRRYETKVH ::....: : . : ::.: ::::. : : : .: :::::..:::::......:::: CCDS12 GAPCGRISFALRYLYGSDQLVVRILQALDLPAKDSNGFSDPYVKIYLLPDRKKKFQTKVH 300 310 320 330 340 350 170 180 190 200 210 220 pF1KB6 RQTLNPHFGETFAFKVPYVELGGRVLVMAVYDFDRFSRNDAIGEVRVP----MSSVDLGR :.:::: :.::: :.:: .::. : : ..:::::::::.: ::.: . .. : CCDS12 RKTLNPVFNETFQFSVPLAELAQRKLHFSVYDFDRFSRHDLIGQVVLDNLLELAEQPPDR 360 370 380 390 400 410 230 240 250 260 270 280 pF1KB6 PVQAWRELQAAPREEQEKLGDICFSLRYVPTAGKLTVIVLEAKNLKKMDVGGLSDPYVKV :. ::.. . :. . ::.. ::: :.::::.::: ...:.::: ::. :.::::::. CCDS12 PL--WRDIVEGGSEKAD-LGELNFSLCYLPTAGRLTVTIIKASNLKAMDLTGFSDPYVKA 420 430 440 450 460 470 290 300 310 320 330 340 pF1KB6 HLLQGGKKVRKKKTTIKKNTLNPYYNEAFSFEVPCDQVQKVQVELTVLDYDKLGKNEAIG :.. :....:.::.:::::::: ::::. :.: ..:..: . ..:.::: .:.::.:: CCDS12 SLISEGRRLKKRKTSIKKNTLNPTYNEALVFDVAPESVENVGLSIAVVDYDCIGHNEVIG 480 490 500 510 520 530 350 360 370 380 pF1KB6 RVAVGA-AAGGAGLRHWADMLANPRRPIAQWHSLRPPDRVRLLPAP :: :: : .:::.::::::.:. .::.: CCDS12 VCRVGPDAADPHGREHWAEMLANPRKPVEHWHQLVEEKTVTSFTKGSKGLSEKENSE 540 550 560 570 580 590 >>CCDS31577.1 SYT7 gene_id:9066|Hs108|chr11 (403 aa) initn: 873 init1: 650 opt: 894 Z-score: 799.4 bits: 156.7 E(32554): 3.3e-38 Smith-Waterman score: 897; 36.9% identity (65.0% similar) in 409 aa overlap (3-375:5-402) 10 20 30 40 50 pF1KB6 MFPEPPTPGPPSPDTPPDSSRISHGPVPPWALATIVLVSGLLIFSCCFCLYRKSCRRR :: .:: :: :. :. :. .:.. :.. :: : .: . . : . CCDS31 MYRDPEAASPGAPSRDVLLVSAIIT------VSLSVTVVLCGL----CHWCQRKLGKRYK 10 20 30 40 50 60 70 80 90 pF1KB6 ----------TGKKSQAQAQVHLQEV-KGLGQSYIDKVQPEVE---ELEPAPS------- .:. . . ..: :... . . :. : . :: : CCDS31 NSLETVGTPDSGRGRSEKKAIKLPAGGKAVNTAPVPGQTPHDESDRRTEPRSSVSDLVNS 60 70 80 90 100 110 100 110 120 130 140 pF1KB6 --------GPGQQVADKHE------LGRLQYSLDYDFQSGQLLVGILQAMGLAALDLGGS .::.. . :: :::.:.:. :.:: . : : :..:. : : :..:. CCDS31 LTSEMLMLSPGSEEDEAHEGCSRENLGRIQFSVGYNFQESTLTVKIMKAQELPAKDFSGT 120 130 140 150 160 170 150 160 170 180 190 200 pF1KB6 SDPYVRVYLLPDKRRRYETKVHRQTLNPHFGETFAFK-VPYVELGGRVLVMAVYDFDRFS :::.:..::::::... ::::.:..::::..::: :. :: .. :.: . : :.:::: CCDS31 SDPFVKIYLLPDKKHKLETKVKRKNLNPHWNETFLFEGFPYEKVVQRILYLQVLDYDRFS 180 190 200 210 220 230 210 220 230 240 250 260 pF1KB6 RNDAIGEVRVPMSSVDLGRPVQAWRELQAAPREEQEKLGDICFSLRYVPTAGKLTVIVLE ::: :::: .:...::: . :..:. . :.. .:: : :.:... : ... CCDS31 RNDPIGEVSIPLNKVDLTQMQTFWKDLKPCSDGSGSR-GELLLSLCYNPSANSIIVNIIK 240 250 260 270 280 270 280 290 300 310 320 pF1KB6 AKNLKKMDVGGLSDPYVKVHLLQGGKKVRKKKTTIKKNTLNPYYNEAFSFEVPCDQVQKV :.::: ::.:: ::::::: :. :.:.::::. : .::: .::.:.:..: ...... CCDS31 ARNLKAMDIGGTSDPYVKVWLMYKDKRVEKKKTVTMKRNLNPIFNESFAFDIPTEKLRET 290 300 310 320 330 340 330 340 350 360 370 380 pF1KB6 QVELTVLDYDKLGKNEAIGRVAVGAAAGGAGLRHWADMLANPRRPIAQWHSLRPPDRVRL . .::.: :::..:..::.. .. .: . ..:: ::.: ::.:.::::.:. CCDS31 TIIITVMDKDKLSRNDVIGKIYLSWKSGPGEVKHWKDMIARPRQPVAQWHQLKA 350 360 370 380 390 400 pF1KB6 LPAP 386 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 17:09:06 2016 done: Fri Nov 4 17:09:06 2016 Total Scan time: 3.340 Total Display time: 0.060 Function used was FASTA [36.3.4 Apr, 2011]