FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6520, 386 aa 1>>>pF1KB6520 386 - 386 aa - 386 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.5888+/-0.000336; mu= 15.7765+/- 0.021 mean_var=84.8552+/-16.772, 0's: 0 Z-trim(117.2): 77 B-trim: 541 in 1/52 Lambda= 0.139231 statistics sampled from 28973 (29052) to 28973 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.722), E-opt: 0.2 (0.341), width: 16 Scan time: 7.330 The best scores are: opt bits E(85289) NP_787063 (OMIM: 606588) DNA (cytosine-5)-methyltr ( 386) 2693 550.7 2.2e-156 NP_037501 (OMIM: 606588) DNA (cytosine-5)-methyltr ( 387) 2681 548.2 1.2e-155 XP_005264234 (OMIM: 602769,615879) PREDICTED: DNA ( 689) 650 140.5 1.2e-32 XP_016859016 (OMIM: 602769,615879) PREDICTED: DNA ( 689) 650 140.5 1.2e-32 XP_011530969 (OMIM: 602769,615879) PREDICTED: DNA ( 689) 650 140.5 1.2e-32 NP_715640 (OMIM: 602769,615879) DNA (cytosine-5)-m ( 723) 650 140.5 1.2e-32 XP_011530968 (OMIM: 602769,615879) PREDICTED: DNA ( 736) 650 140.5 1.2e-32 NP_001307822 (OMIM: 602769,615879) DNA (cytosine-5 ( 760) 650 140.5 1.3e-32 XP_011530966 (OMIM: 602769,615879) PREDICTED: DNA ( 781) 650 140.5 1.3e-32 XP_011530965 (OMIM: 602769,615879) PREDICTED: DNA ( 857) 650 140.5 1.4e-32 XP_011530964 (OMIM: 602769,615879) PREDICTED: DNA ( 863) 650 140.5 1.4e-32 NP_783328 (OMIM: 602769,615879) DNA (cytosine-5)-m ( 912) 650 140.6 1.5e-32 XP_005264232 (OMIM: 602769,615879) PREDICTED: DNA ( 912) 650 140.6 1.5e-32 NP_072046 (OMIM: 602769,615879) DNA (cytosine-5)-m ( 912) 650 140.6 1.5e-32 XP_016859015 (OMIM: 602769,615879) PREDICTED: DNA ( 912) 650 140.6 1.5e-32 NP_001193985 (OMIM: 242860,602900) DNA (cytosine-5 ( 694) 623 135.0 5.1e-31 NP_001193984 (OMIM: 242860,602900) DNA (cytosine-5 ( 728) 623 135.1 5.3e-31 XP_011526956 (OMIM: 242860,602900) PREDICTED: DNA ( 740) 623 135.1 5.3e-31 NP_787045 (OMIM: 242860,602900) DNA (cytosine-5)-m ( 770) 623 135.1 5.5e-31 XP_011526955 (OMIM: 242860,602900) PREDICTED: DNA ( 782) 623 135.1 5.6e-31 NP_787044 (OMIM: 242860,602900) DNA (cytosine-5)-m ( 833) 623 135.1 5.9e-31 NP_787046 (OMIM: 242860,602900) DNA (cytosine-5)-m ( 845) 623 135.1 5.9e-31 NP_008823 (OMIM: 242860,602900) DNA (cytosine-5)-m ( 853) 623 135.1 6e-31 XP_006724731 (OMIM: 300032,300448,300504,301040,30 (1871) 175 45.4 0.0014 XP_016885100 (OMIM: 300032,300448,300504,301040,30 (2370) 175 45.4 0.0016 XP_016885099 (OMIM: 300032,300448,300504,301040,30 (2385) 175 45.5 0.0016 XP_016885098 (OMIM: 300032,300448,300504,301040,30 (2386) 175 45.5 0.0016 XP_016885097 (OMIM: 300032,300448,300504,301040,30 (2398) 175 45.5 0.0016 XP_006724730 (OMIM: 300032,300448,300504,301040,30 (2399) 175 45.5 0.0016 XP_016885096 (OMIM: 300032,300448,300504,301040,30 (2414) 175 45.5 0.0016 XP_016885095 (OMIM: 300032,300448,300504,301040,30 (2415) 175 45.5 0.0016 XP_016885094 (OMIM: 300032,300448,300504,301040,30 (2424) 175 45.5 0.0017 XP_005262214 (OMIM: 300032,300448,300504,301040,30 (2424) 175 45.5 0.0017 XP_016885093 (OMIM: 300032,300448,300504,301040,30 (2425) 175 45.5 0.0017 XP_016885092 (OMIM: 300032,300448,300504,301040,30 (2436) 175 45.5 0.0017 XP_005262213 (OMIM: 300032,300448,300504,301040,30 (2437) 175 45.5 0.0017 XP_016885091 (OMIM: 300032,300448,300504,301040,30 (2452) 175 45.5 0.0017 XP_005262212 (OMIM: 300032,300448,300504,301040,30 (2453) 175 45.5 0.0017 XP_006724729 (OMIM: 300032,300448,300504,301040,30 (2453) 175 45.5 0.0017 NP_612114 (OMIM: 300032,300448,300504,301040,30958 (2454) 175 45.5 0.0017 XP_016885090 (OMIM: 300032,300448,300504,301040,30 (2462) 175 45.5 0.0017 XP_005262211 (OMIM: 300032,300448,300504,301040,30 (2463) 175 45.5 0.0017 XP_005262210 (OMIM: 300032,300448,300504,301040,30 (2491) 175 45.5 0.0017 NP_000480 (OMIM: 300032,300448,300504,301040,30958 (2492) 175 45.5 0.0017 >>NP_787063 (OMIM: 606588) DNA (cytosine-5)-methyltransf (386 aa) initn: 2693 init1: 2693 opt: 2693 Z-score: 2928.6 bits: 550.7 E(85289): 2.2e-156 Smith-Waterman score: 2693; 99.7% identity (99.7% similar) in 386 aa overlap (1-386:1-386) 10 20 30 40 50 60 pF1KB6 MAAIPALDPEAEPSMDVILVGSSELSSSVSPGTGRDLIAYEVKANQRNIEDICICCGSLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_787 MAAIPALDPEAEPSMDVILVGSSELSSSVSPGTGRDLIAYEVKANQRNIEDICICCGSLQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 VHTQHPLFEGGICAPCKDKFLDALFLYDDDGYQSYCSICCSGETLLICGNPDCTRCYCFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_787 VHTQHPLFEGGICAPCKDKFLDALFLYDDDGYQSYCSICCSGETLLICGNPDCTRCYCFE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 CVDSLVGPGTSGKVHAMSNWVCYLCLPSSRSGLLQRRRKWRSQLKAFYDRESENPLEMFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_787 CVDSLVGPGTSGKVHAMSNWVCYLCLPSSRSGLLQRRRKWRSQLKAFYDRESENPLEMFE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 TVPVWRRQPVRVLSLFEDIKKELTSLGFLESGSDPGQLKHVVDVTDTVRKDVEEWGPFDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_787 TVPVWRRQPVRVLSLFEDIKKELTSLGFLESGSDPGQLKHVVDVTDTVRKDVEEWGPFDL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 VYGATPPLGHTCDRPPSWYLFQFHRLLQYARPKPGSPGPFFWMFVDNLVLNKEDLDVASR ::::::::::::::::::::::::::::::::::::: :::::::::::::::::::::: NP_787 VYGATPPLGHTCDRPPSWYLFQFHRLLQYARPKPGSPRPFFWMFVDNLVLNKEDLDVASR 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 FLEMEPVTIPDVHGGSLQNAVRVWSNIPAIRSRHWALVSEEELSLLAQNKQSSKLAAKWP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_787 FLEMEPVTIPDVHGGSLQNAVRVWSNIPAIRSRHWALVSEEELSLLAQNKQSSKLAAKWP 310 320 330 340 350 360 370 380 pF1KB6 TKLVKNCFLPLREYFKYFSTELTSSL :::::::::::::::::::::::::: NP_787 TKLVKNCFLPLREYFKYFSTELTSSL 370 380 >>NP_037501 (OMIM: 606588) DNA (cytosine-5)-methyltransf (387 aa) initn: 2343 init1: 2343 opt: 2681 Z-score: 2915.6 bits: 548.2 E(85289): 1.2e-155 Smith-Waterman score: 2681; 99.5% identity (99.5% similar) in 387 aa overlap (1-386:1-387) 10 20 30 40 50 60 pF1KB6 MAAIPALDPEAEPSMDVILVGSSELSSSVSPGTGRDLIAYEVKANQRNIEDICICCGSLQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 MAAIPALDPEAEPSMDVILVGSSELSSSVSPGTGRDLIAYEVKANQRNIEDICICCGSLQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 VHTQHPLFEGGICAPCKDKFLDALFLYDDDGYQSYCSICCSGETLLICGNPDCTRCYCFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 VHTQHPLFEGGICAPCKDKFLDALFLYDDDGYQSYCSICCSGETLLICGNPDCTRCYCFE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 CVDSLVGPGTSGKVHAMSNWVCYLCLPSSRSGLLQRRRKWRSQLKAFYDRESENPLEMFE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 CVDSLVGPGTSGKVHAMSNWVCYLCLPSSRSGLLQRRRKWRSQLKAFYDRESENPLEMFE 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 TVPVWRRQPVRVLSLFEDIKKELTSLGFLESGSDPGQLKHVVDVTDTVRKDVEEWGPFDL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_037 TVPVWRRQPVRVLSLFEDIKKELTSLGFLESGSDPGQLKHVVDVTDTVRKDVEEWGPFDL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 VYGATPPLGHTCDRPPSWYLFQFHRLLQYARPKPGSPGPFFWMFVDNLVLNKEDLDVASR ::::::::::::::::::::::::::::::::::::: :::::::::::::::::::::: NP_037 VYGATPPLGHTCDRPPSWYLFQFHRLLQYARPKPGSPRPFFWMFVDNLVLNKEDLDVASR 250 260 270 280 290 300 310 320 330 340 350 pF1KB6 FLEMEPVTIPDVHGGSLQNAVRVWSNIPAIRS-RHWALVSEEELSLLAQNKQSSKLAAKW :::::::::::::::::::::::::::::::: ::::::::::::::::::::::::::: NP_037 FLEMEPVTIPDVHGGSLQNAVRVWSNIPAIRSSRHWALVSEEELSLLAQNKQSSKLAAKW 310 320 330 340 350 360 360 370 380 pF1KB6 PTKLVKNCFLPLREYFKYFSTELTSSL ::::::::::::::::::::::::::: NP_037 PTKLVKNCFLPLREYFKYFSTELTSSL 370 380 >>XP_005264234 (OMIM: 602769,615879) PREDICTED: DNA (cyt (689 aa) initn: 948 init1: 565 opt: 650 Z-score: 707.2 bits: 140.5 E(85289): 1.2e-32 Smith-Waterman score: 875; 40.5% identity (65.1% similar) in 341 aa overlap (35-345:253-592) 10 20 30 40 50 60 pF1KB6 PALDPEAEPSMDVILVGSSELSSSVSPGTGRDLIAYEVKANQRNIEDICICCGSLQVHTQ :. ..:::. . :::::::: ::::.: . XP_005 AAYAPPPPAKKPRKSTAEKPKVKEIIDERTRERLVYEVRQKCRNIEDICISCGSLNVTLE 230 240 250 260 270 280 70 80 90 100 110 120 pF1KB6 HPLFEGGICAPCKDKFLDALFLYDDDGYQSYCSICCSGETLLICGNPDCTRCYCFECVDS :::: ::.: ::. ::. . ::::::::::.:::.:. .:.::: .: ::.: :::: XP_005 HPLFVGGMCQNCKNCFLECAYQYDDDGYQSYCTICCGGREVLMCGNNNCCRCFCVECVDL 290 300 310 320 330 340 130 140 150 160 170 180 pF1KB6 LVGPGTSGKVHAMSNWVCYLCLPSSRSGLLQRRRKWRSQLKAFY--DRESE-NPLEMFET :::::.. . . : ::.: .. :::.::. : :.:. :. ....: .: ... XP_005 LVGPGAAQAAIKEDPWNCYMCGHKGTYGLLRRREDWPSRLQMFFANNHDQEFDPPKVYPP 350 360 370 380 390 400 190 200 210 220 pF1KB6 VPVWRRQPVRVLSLFEDIKKELTSLGFL-------------ESGSDPGQLKH------VV ::. .:.:.::::::. : : : : :.. :...: : XP_005 VPAEKRKPIRVLSLFDGIATGLLVLKDLGIQVDRYIASEVCEDSITVGMVRHQGKIMYVG 410 420 430 440 450 460 230 240 250 260 270 pF1KB6 DVTDTVRKDVEEWGPFDLVYGATP--------PLGHTCDRPPSWYLFQFHRLLQYARPKP :: ....: ..:::::::: :..: : . . . .:.:.:::. :::: XP_005 DVRSVTQKHIQEWGPFDLVIGGSPCNDLSIVNPARKGLYEGTGRLFFEFYRLLHDARPKE 470 480 490 500 510 520 280 290 300 310 320 330 pF1KB6 GSPGPFFWMFVDNLVLNKEDLDVASRFLEMEPVTIPDVHGGSLQNAVRVWSNIPAIRSRH :. ::::.: . .... : ::::: .:: : . .. . : :.:.:.. .: XP_005 GDDRPFFWLFENVVAMGVSDKRDISRFLESNPVMIDAKEVSAAHRARYFWGNLPGM-NRP 530 540 550 560 570 580 340 350 360 370 380 pF1KB6 WALVSEEELSLLAQNKQSSKLAAKWPTKLVKNCFLPLREYFKYFSTELTSSL : . ...: : XP_005 LASTVNDKLELQECLEHGRIAKFSKVRTITTRSNSIKQGKDQHFPVFMNEKEDILWCTEM 590 600 610 620 630 640 >>XP_016859016 (OMIM: 602769,615879) PREDICTED: DNA (cyt (689 aa) initn: 948 init1: 565 opt: 650 Z-score: 707.2 bits: 140.5 E(85289): 1.2e-32 Smith-Waterman score: 875; 40.5% identity (65.1% similar) in 341 aa overlap (35-345:253-592) 10 20 30 40 50 60 pF1KB6 PALDPEAEPSMDVILVGSSELSSSVSPGTGRDLIAYEVKANQRNIEDICICCGSLQVHTQ :. ..:::. . :::::::: ::::.: . XP_016 AAYAPPPPAKKPRKSTAEKPKVKEIIDERTRERLVYEVRQKCRNIEDICISCGSLNVTLE 230 240 250 260 270 280 70 80 90 100 110 120 pF1KB6 HPLFEGGICAPCKDKFLDALFLYDDDGYQSYCSICCSGETLLICGNPDCTRCYCFECVDS :::: ::.: ::. ::. . ::::::::::.:::.:. .:.::: .: ::.: :::: XP_016 HPLFVGGMCQNCKNCFLECAYQYDDDGYQSYCTICCGGREVLMCGNNNCCRCFCVECVDL 290 300 310 320 330 340 130 140 150 160 170 180 pF1KB6 LVGPGTSGKVHAMSNWVCYLCLPSSRSGLLQRRRKWRSQLKAFY--DRESE-NPLEMFET :::::.. . . : ::.: .. :::.::. : :.:. :. ....: .: ... XP_016 LVGPGAAQAAIKEDPWNCYMCGHKGTYGLLRRREDWPSRLQMFFANNHDQEFDPPKVYPP 350 360 370 380 390 400 190 200 210 220 pF1KB6 VPVWRRQPVRVLSLFEDIKKELTSLGFL-------------ESGSDPGQLKH------VV ::. .:.:.::::::. : : : : :.. :...: : XP_016 VPAEKRKPIRVLSLFDGIATGLLVLKDLGIQVDRYIASEVCEDSITVGMVRHQGKIMYVG 410 420 430 440 450 460 230 240 250 260 270 pF1KB6 DVTDTVRKDVEEWGPFDLVYGATP--------PLGHTCDRPPSWYLFQFHRLLQYARPKP :: ....: ..:::::::: :..: : . . . .:.:.:::. :::: XP_016 DVRSVTQKHIQEWGPFDLVIGGSPCNDLSIVNPARKGLYEGTGRLFFEFYRLLHDARPKE 470 480 490 500 510 520 280 290 300 310 320 330 pF1KB6 GSPGPFFWMFVDNLVLNKEDLDVASRFLEMEPVTIPDVHGGSLQNAVRVWSNIPAIRSRH :. ::::.: . .... : ::::: .:: : . .. . : :.:.:.. .: XP_016 GDDRPFFWLFENVVAMGVSDKRDISRFLESNPVMIDAKEVSAAHRARYFWGNLPGM-NRP 530 540 550 560 570 580 340 350 360 370 380 pF1KB6 WALVSEEELSLLAQNKQSSKLAAKWPTKLVKNCFLPLREYFKYFSTELTSSL : . ...: : XP_016 LASTVNDKLELQECLEHGRIAKFSKVRTITTRSNSIKQGKDQHFPVFMNEKEDILWCTEM 590 600 610 620 630 640 >>XP_011530969 (OMIM: 602769,615879) PREDICTED: DNA (cyt (689 aa) initn: 948 init1: 565 opt: 650 Z-score: 707.2 bits: 140.5 E(85289): 1.2e-32 Smith-Waterman score: 875; 40.5% identity (65.1% similar) in 341 aa overlap (35-345:253-592) 10 20 30 40 50 60 pF1KB6 PALDPEAEPSMDVILVGSSELSSSVSPGTGRDLIAYEVKANQRNIEDICICCGSLQVHTQ :. ..:::. . :::::::: ::::.: . XP_011 AAYAPPPPAKKPRKSTAEKPKVKEIIDERTRERLVYEVRQKCRNIEDICISCGSLNVTLE 230 240 250 260 270 280 70 80 90 100 110 120 pF1KB6 HPLFEGGICAPCKDKFLDALFLYDDDGYQSYCSICCSGETLLICGNPDCTRCYCFECVDS :::: ::.: ::. ::. . ::::::::::.:::.:. .:.::: .: ::.: :::: XP_011 HPLFVGGMCQNCKNCFLECAYQYDDDGYQSYCTICCGGREVLMCGNNNCCRCFCVECVDL 290 300 310 320 330 340 130 140 150 160 170 180 pF1KB6 LVGPGTSGKVHAMSNWVCYLCLPSSRSGLLQRRRKWRSQLKAFY--DRESE-NPLEMFET :::::.. . . : ::.: .. :::.::. : :.:. :. ....: .: ... XP_011 LVGPGAAQAAIKEDPWNCYMCGHKGTYGLLRRREDWPSRLQMFFANNHDQEFDPPKVYPP 350 360 370 380 390 400 190 200 210 220 pF1KB6 VPVWRRQPVRVLSLFEDIKKELTSLGFL-------------ESGSDPGQLKH------VV ::. .:.:.::::::. : : : : :.. :...: : XP_011 VPAEKRKPIRVLSLFDGIATGLLVLKDLGIQVDRYIASEVCEDSITVGMVRHQGKIMYVG 410 420 430 440 450 460 230 240 250 260 270 pF1KB6 DVTDTVRKDVEEWGPFDLVYGATP--------PLGHTCDRPPSWYLFQFHRLLQYARPKP :: ....: ..:::::::: :..: : . . . .:.:.:::. :::: XP_011 DVRSVTQKHIQEWGPFDLVIGGSPCNDLSIVNPARKGLYEGTGRLFFEFYRLLHDARPKE 470 480 490 500 510 520 280 290 300 310 320 330 pF1KB6 GSPGPFFWMFVDNLVLNKEDLDVASRFLEMEPVTIPDVHGGSLQNAVRVWSNIPAIRSRH :. ::::.: . .... : ::::: .:: : . .. . : :.:.:.. .: XP_011 GDDRPFFWLFENVVAMGVSDKRDISRFLESNPVMIDAKEVSAAHRARYFWGNLPGM-NRP 530 540 550 560 570 580 340 350 360 370 380 pF1KB6 WALVSEEELSLLAQNKQSSKLAAKWPTKLVKNCFLPLREYFKYFSTELTSSL : . ...: : XP_011 LASTVNDKLELQECLEHGRIAKFSKVRTITTRSNSIKQGKDQHFPVFMNEKEDILWCTEM 590 600 610 620 630 640 >>NP_715640 (OMIM: 602769,615879) DNA (cytosine-5)-methy (723 aa) initn: 948 init1: 565 opt: 650 Z-score: 707.0 bits: 140.5 E(85289): 1.2e-32 Smith-Waterman score: 875; 40.5% identity (65.1% similar) in 341 aa overlap (35-345:287-626) 10 20 30 40 50 60 pF1KB6 PALDPEAEPSMDVILVGSSELSSSVSPGTGRDLIAYEVKANQRNIEDICICCGSLQVHTQ :. ..:::. . :::::::: ::::.: . NP_715 AAYAPPPPAKKPRKSTAEKPKVKEIIDERTRERLVYEVRQKCRNIEDICISCGSLNVTLE 260 270 280 290 300 310 70 80 90 100 110 120 pF1KB6 HPLFEGGICAPCKDKFLDALFLYDDDGYQSYCSICCSGETLLICGNPDCTRCYCFECVDS :::: ::.: ::. ::. . ::::::::::.:::.:. .:.::: .: ::.: :::: NP_715 HPLFVGGMCQNCKNCFLECAYQYDDDGYQSYCTICCGGREVLMCGNNNCCRCFCVECVDL 320 330 340 350 360 370 130 140 150 160 170 180 pF1KB6 LVGPGTSGKVHAMSNWVCYLCLPSSRSGLLQRRRKWRSQLKAFY--DRESE-NPLEMFET :::::.. . . : ::.: .. :::.::. : :.:. :. ....: .: ... NP_715 LVGPGAAQAAIKEDPWNCYMCGHKGTYGLLRRREDWPSRLQMFFANNHDQEFDPPKVYPP 380 390 400 410 420 430 190 200 210 220 pF1KB6 VPVWRRQPVRVLSLFEDIKKELTSLGFL-------------ESGSDPGQLKH------VV ::. .:.:.::::::. : : : : :.. :...: : NP_715 VPAEKRKPIRVLSLFDGIATGLLVLKDLGIQVDRYIASEVCEDSITVGMVRHQGKIMYVG 440 450 460 470 480 490 230 240 250 260 270 pF1KB6 DVTDTVRKDVEEWGPFDLVYGATP--------PLGHTCDRPPSWYLFQFHRLLQYARPKP :: ....: ..:::::::: :..: : . . . .:.:.:::. :::: NP_715 DVRSVTQKHIQEWGPFDLVIGGSPCNDLSIVNPARKGLYEGTGRLFFEFYRLLHDARPKE 500 510 520 530 540 550 280 290 300 310 320 330 pF1KB6 GSPGPFFWMFVDNLVLNKEDLDVASRFLEMEPVTIPDVHGGSLQNAVRVWSNIPAIRSRH :. ::::.: . .... : ::::: .:: : . .. . : :.:.:.. .: NP_715 GDDRPFFWLFENVVAMGVSDKRDISRFLESNPVMIDAKEVSAAHRARYFWGNLPGM-NRP 560 570 580 590 600 610 340 350 360 370 380 pF1KB6 WALVSEEELSLLAQNKQSSKLAAKWPTKLVKNCFLPLREYFKYFSTELTSSL : . ...: : NP_715 LASTVNDKLELQECLEHGRIAKFSKVRTITTRSNSIKQGKDQHFPVFMNEKEDILWCTEM 620 630 640 650 660 670 >>XP_011530968 (OMIM: 602769,615879) PREDICTED: DNA (cyt (736 aa) initn: 948 init1: 565 opt: 650 Z-score: 706.8 bits: 140.5 E(85289): 1.2e-32 Smith-Waterman score: 875; 40.5% identity (65.1% similar) in 341 aa overlap (35-345:300-639) 10 20 30 40 50 60 pF1KB6 PALDPEAEPSMDVILVGSSELSSSVSPGTGRDLIAYEVKANQRNIEDICICCGSLQVHTQ :. ..:::. . :::::::: ::::.: . XP_011 AAYAPPPPAKKPRKSTAEKPKVKEIIDERTRERLVYEVRQKCRNIEDICISCGSLNVTLE 270 280 290 300 310 320 70 80 90 100 110 120 pF1KB6 HPLFEGGICAPCKDKFLDALFLYDDDGYQSYCSICCSGETLLICGNPDCTRCYCFECVDS :::: ::.: ::. ::. . ::::::::::.:::.:. .:.::: .: ::.: :::: XP_011 HPLFVGGMCQNCKNCFLECAYQYDDDGYQSYCTICCGGREVLMCGNNNCCRCFCVECVDL 330 340 350 360 370 380 130 140 150 160 170 180 pF1KB6 LVGPGTSGKVHAMSNWVCYLCLPSSRSGLLQRRRKWRSQLKAFY--DRESE-NPLEMFET :::::.. . . : ::.: .. :::.::. : :.:. :. ....: .: ... XP_011 LVGPGAAQAAIKEDPWNCYMCGHKGTYGLLRRREDWPSRLQMFFANNHDQEFDPPKVYPP 390 400 410 420 430 440 190 200 210 220 pF1KB6 VPVWRRQPVRVLSLFEDIKKELTSLGFL-------------ESGSDPGQLKH------VV ::. .:.:.::::::. : : : : :.. :...: : XP_011 VPAEKRKPIRVLSLFDGIATGLLVLKDLGIQVDRYIASEVCEDSITVGMVRHQGKIMYVG 450 460 470 480 490 500 230 240 250 260 270 pF1KB6 DVTDTVRKDVEEWGPFDLVYGATP--------PLGHTCDRPPSWYLFQFHRLLQYARPKP :: ....: ..:::::::: :..: : . . . .:.:.:::. :::: XP_011 DVRSVTQKHIQEWGPFDLVIGGSPCNDLSIVNPARKGLYEGTGRLFFEFYRLLHDARPKE 510 520 530 540 550 560 280 290 300 310 320 330 pF1KB6 GSPGPFFWMFVDNLVLNKEDLDVASRFLEMEPVTIPDVHGGSLQNAVRVWSNIPAIRSRH :. ::::.: . .... : ::::: .:: : . .. . : :.:.:.. .: XP_011 GDDRPFFWLFENVVAMGVSDKRDISRFLESNPVMIDAKEVSAAHRARYFWGNLPGM-NRP 570 580 590 600 610 620 340 350 360 370 380 pF1KB6 WALVSEEELSLLAQNKQSSKLAAKWPTKLVKNCFLPLREYFKYFSTELTSSL : . ...: : XP_011 LASTVNDKLELQECLEHGRIAKFSKVRTITTRSNSIKQGKDQHFPVFMNEKEDILWCTEM 630 640 650 660 670 680 >>NP_001307822 (OMIM: 602769,615879) DNA (cytosine-5)-me (760 aa) initn: 948 init1: 565 opt: 650 Z-score: 706.7 bits: 140.5 E(85289): 1.3e-32 Smith-Waterman score: 875; 40.5% identity (65.1% similar) in 341 aa overlap (35-345:324-663) 10 20 30 40 50 60 pF1KB6 PALDPEAEPSMDVILVGSSELSSSVSPGTGRDLIAYEVKANQRNIEDICICCGSLQVHTQ :. ..:::. . :::::::: ::::.: . NP_001 AAYAPPPPAKKPRKSTAEKPKVKEIIDERTRERLVYEVRQKCRNIEDICISCGSLNVTLE 300 310 320 330 340 350 70 80 90 100 110 120 pF1KB6 HPLFEGGICAPCKDKFLDALFLYDDDGYQSYCSICCSGETLLICGNPDCTRCYCFECVDS :::: ::.: ::. ::. . ::::::::::.:::.:. .:.::: .: ::.: :::: NP_001 HPLFVGGMCQNCKNCFLECAYQYDDDGYQSYCTICCGGREVLMCGNNNCCRCFCVECVDL 360 370 380 390 400 410 130 140 150 160 170 180 pF1KB6 LVGPGTSGKVHAMSNWVCYLCLPSSRSGLLQRRRKWRSQLKAFY--DRESE-NPLEMFET :::::.. . . : ::.: .. :::.::. : :.:. :. ....: .: ... NP_001 LVGPGAAQAAIKEDPWNCYMCGHKGTYGLLRRREDWPSRLQMFFANNHDQEFDPPKVYPP 420 430 440 450 460 470 190 200 210 220 pF1KB6 VPVWRRQPVRVLSLFEDIKKELTSLGFL-------------ESGSDPGQLKH------VV ::. .:.:.::::::. : : : : :.. :...: : NP_001 VPAEKRKPIRVLSLFDGIATGLLVLKDLGIQVDRYIASEVCEDSITVGMVRHQGKIMYVG 480 490 500 510 520 530 230 240 250 260 270 pF1KB6 DVTDTVRKDVEEWGPFDLVYGATP--------PLGHTCDRPPSWYLFQFHRLLQYARPKP :: ....: ..:::::::: :..: : . . . .:.:.:::. :::: NP_001 DVRSVTQKHIQEWGPFDLVIGGSPCNDLSIVNPARKGLYEGTGRLFFEFYRLLHDARPKE 540 550 560 570 580 590 280 290 300 310 320 330 pF1KB6 GSPGPFFWMFVDNLVLNKEDLDVASRFLEMEPVTIPDVHGGSLQNAVRVWSNIPAIRSRH :. ::::.: . .... : ::::: .:: : . .. . : :.:.:.. .: NP_001 GDDRPFFWLFENVVAMGVSDKRDISRFLESNPVMIDAKEVSAAHRARYFWGNLPGM-NRP 600 610 620 630 640 650 340 350 360 370 380 pF1KB6 WALVSEEELSLLAQNKQSSKLAAKWPTKLVKNCFLPLREYFKYFSTELTSSL : . ...: : NP_001 LASTVNDKLELQECLEHGRIAKFSKVRTITTRSNSIKQGKDQHFPVFMNEKEDILWCTEM 660 670 680 690 700 710 >>XP_011530966 (OMIM: 602769,615879) PREDICTED: DNA (cyt (781 aa) initn: 879 init1: 565 opt: 650 Z-score: 706.5 bits: 140.5 E(85289): 1.3e-32 Smith-Waterman score: 832; 42.2% identity (66.1% similar) in 301 aa overlap (35-305:476-776) 10 20 30 40 50 60 pF1KB6 PALDPEAEPSMDVILVGSSELSSSVSPGTGRDLIAYEVKANQRNIEDICICCGSLQVHTQ :. ..:::. . :::::::: ::::.: . XP_011 AAYAPPPPAKKPRKSTAEKPKVKEIIDERTRERLVYEVRQKCRNIEDICISCGSLNVTLE 450 460 470 480 490 500 70 80 90 100 110 120 pF1KB6 HPLFEGGICAPCKDKFLDALFLYDDDGYQSYCSICCSGETLLICGNPDCTRCYCFECVDS :::: ::.: ::. ::. . ::::::::::.:::.:. .:.::: .: ::.: :::: XP_011 HPLFVGGMCQNCKNCFLECAYQYDDDGYQSYCTICCGGREVLMCGNNNCCRCFCVECVDL 510 520 530 540 550 560 130 140 150 160 170 180 pF1KB6 LVGPGTSGKVHAMSNWVCYLCLPSSRSGLLQRRRKWRSQLKAFY--DRESE-NPLEMFET :::::.. . . : ::.: .. :::.::. : :.:. :. ....: .: ... XP_011 LVGPGAAQAAIKEDPWNCYMCGHKGTYGLLRRREDWPSRLQMFFANNHDQEFDPPKVYPP 570 580 590 600 610 620 190 200 210 220 pF1KB6 VPVWRRQPVRVLSLFEDIKKELTSLGFL-------------ESGSDPGQLKH------VV ::. .:.:.::::::. : : : : :.. :...: : XP_011 VPAEKRKPIRVLSLFDGIATGLLVLKDLGIQVDRYIASEVCEDSITVGMVRHQGKIMYVG 630 640 650 660 670 680 230 240 250 260 270 pF1KB6 DVTDTVRKDVEEWGPFDLVYGATP--------PLGHTCDRPPSWYLFQFHRLLQYARPKP :: ....: ..:::::::: :..: : . . . .:.:.:::. :::: XP_011 DVRSVTQKHIQEWGPFDLVIGGSPCNDLSIVNPARKGLYEGTGRLFFEFYRLLHDARPKE 690 700 710 720 730 740 280 290 300 310 320 330 pF1KB6 GSPGPFFWMFVDNLVLNKEDLDVASRFLEMEPVTIPDVHGGSLQNAVRVWSNIPAIRSRH :. ::::.: . .... : :::::.. XP_011 GDDRPFFWLFENVVAMGVSDKRDISRFLEVQNSHLY 750 760 770 780 340 350 360 370 380 pF1KB6 WALVSEEELSLLAQNKQSSKLAAKWPTKLVKNCFLPLREYFKYFSTELTSSL >>XP_011530965 (OMIM: 602769,615879) PREDICTED: DNA (cyt (857 aa) initn: 948 init1: 565 opt: 650 Z-score: 705.9 bits: 140.5 E(85289): 1.4e-32 Smith-Waterman score: 875; 40.5% identity (65.1% similar) in 341 aa overlap (35-345:421-760) 10 20 30 40 50 60 pF1KB6 PALDPEAEPSMDVILVGSSELSSSVSPGTGRDLIAYEVKANQRNIEDICICCGSLQVHTQ :. ..:::. . :::::::: ::::.: . XP_011 AAYAPPPPAKKPRKSTAEKPKVKEIIDERTRERLVYEVRQKCRNIEDICISCGSLNVTLE 400 410 420 430 440 450 70 80 90 100 110 120 pF1KB6 HPLFEGGICAPCKDKFLDALFLYDDDGYQSYCSICCSGETLLICGNPDCTRCYCFECVDS :::: ::.: ::. ::. . ::::::::::.:::.:. .:.::: .: ::.: :::: XP_011 HPLFVGGMCQNCKNCFLECAYQYDDDGYQSYCTICCGGREVLMCGNNNCCRCFCVECVDL 460 470 480 490 500 510 130 140 150 160 170 180 pF1KB6 LVGPGTSGKVHAMSNWVCYLCLPSSRSGLLQRRRKWRSQLKAFY--DRESE-NPLEMFET :::::.. . . : ::.: .. :::.::. : :.:. :. ....: .: ... XP_011 LVGPGAAQAAIKEDPWNCYMCGHKGTYGLLRRREDWPSRLQMFFANNHDQEFDPPKVYPP 520 530 540 550 560 570 190 200 210 220 pF1KB6 VPVWRRQPVRVLSLFEDIKKELTSLGFL-------------ESGSDPGQLKH------VV ::. .:.:.::::::. : : : : :.. :...: : XP_011 VPAEKRKPIRVLSLFDGIATGLLVLKDLGIQVDRYIASEVCEDSITVGMVRHQGKIMYVG 580 590 600 610 620 630 230 240 250 260 270 pF1KB6 DVTDTVRKDVEEWGPFDLVYGATP--------PLGHTCDRPPSWYLFQFHRLLQYARPKP :: ....: ..:::::::: :..: : . . . .:.:.:::. :::: XP_011 DVRSVTQKHIQEWGPFDLVIGGSPCNDLSIVNPARKGLYEGTGRLFFEFYRLLHDARPKE 640 650 660 670 680 690 280 290 300 310 320 330 pF1KB6 GSPGPFFWMFVDNLVLNKEDLDVASRFLEMEPVTIPDVHGGSLQNAVRVWSNIPAIRSRH :. ::::.: . .... : ::::: .:: : . .. . : :.:.:.. .: XP_011 GDDRPFFWLFENVVAMGVSDKRDISRFLESNPVMIDAKEVSAAHRARYFWGNLPGM-NRP 700 710 720 730 740 340 350 360 370 380 pF1KB6 WALVSEEELSLLAQNKQSSKLAAKWPTKLVKNCFLPLREYFKYFSTELTSSL : . ...: : XP_011 LASTVNDKLELQECLEHGRIAKFSKVRTITTRSNSIKQGKDQHFPVFMNEKEDILWCTEM 750 760 770 780 790 800 386 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 08:02:56 2016 done: Sat Nov 5 08:02:57 2016 Total Scan time: 7.330 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]