FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6522, 387 aa 1>>>pF1KB6522 387 - 387 aa - 387 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.7869+/-0.000975; mu= 14.8046+/- 0.058 mean_var=82.6950+/-16.453, 0's: 0 Z-trim(105.2): 53 B-trim: 0 in 0/51 Lambda= 0.141038 statistics sampled from 8229 (8277) to 8229 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.627), E-opt: 0.2 (0.254), width: 16 Scan time: 2.740 The best scores are: opt bits E(32554) CCDS755.2 SNX7 gene_id:51375|Hs108|chr1 ( 451) 2565 531.9 4.3e-151 CCDS756.2 SNX7 gene_id:51375|Hs108|chr1 ( 396) 1570 329.4 3.4e-90 CCDS43865.1 SNX30 gene_id:401548|Hs108|chr9 ( 437) 1274 269.2 4.9e-72 CCDS3032.1 SNX4 gene_id:8723|Hs108|chr3 ( 450) 330 77.2 3.4e-14 CCDS32268.1 SNX1 gene_id:6642|Hs108|chr15 ( 457) 313 73.7 3.7e-13 CCDS64234.1 SNX2 gene_id:6643|Hs108|chr5 ( 402) 307 72.4 7.9e-13 CCDS34217.1 SNX2 gene_id:6643|Hs108|chr5 ( 519) 307 72.5 9.7e-13 CCDS32266.1 SNX1 gene_id:6642|Hs108|chr15 ( 522) 293 69.7 7e-12 CCDS58371.1 SNX1 gene_id:6642|Hs108|chr15 ( 557) 293 69.7 7.4e-12 >>CCDS755.2 SNX7 gene_id:51375|Hs108|chr1 (451 aa) initn: 2565 init1: 2565 opt: 2565 Z-score: 2826.1 bits: 531.9 E(32554): 4.3e-151 Smith-Waterman score: 2565; 100.0% identity (100.0% similar) in 387 aa overlap (1-387:65-451) 10 20 30 pF1KB6 MDMNSFSPMMPTSPLSMINQIKFEDEPDLK :::::::::::::::::::::::::::::: CCDS75 SGSSALLQAEVLDLDEDEDDLEVFSKDASLMDMNSFSPMMPTSPLSMINQIKFEDEPDLK 40 50 60 70 80 90 40 50 60 70 80 90 pF1KB6 DLFITVDEPESHVTTIETFITYRIITKTSRGEFDSSEFEVRRRYQDFLWLKGKLEEAHPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 DLFITVDEPESHVTTIETFITYRIITKTSRGEFDSSEFEVRRRYQDFLWLKGKLEEAHPT 100 110 120 130 140 150 100 110 120 130 140 150 pF1KB6 LIIPPLPEKFIVKGMVERFNDDFIETRRKALHKFLNRIADHPTLTFNEDFKIFLTAQAWE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 LIIPPLPEKFIVKGMVERFNDDFIETRRKALHKFLNRIADHPTLTFNEDFKIFLTAQAWE 160 170 180 190 200 210 160 170 180 190 200 210 pF1KB6 LSSHKKQGPGLLSRMGQTVRAVASSMRGVKNRPEEFMEMNNFIELFSQKINLIDKISQRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 LSSHKKQGPGLLSRMGQTVRAVASSMRGVKNRPEEFMEMNNFIELFSQKINLIDKISQRI 220 230 240 250 260 270 220 230 240 250 260 270 pF1KB6 YKEEREYFDEMKEYGPIHILWSASEEDLVDTLKDVASCIDRCCKATEKRMSGLSEALLPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 YKEEREYFDEMKEYGPIHILWSASEEDLVDTLKDVASCIDRCCKATEKRMSGLSEALLPV 280 290 300 310 320 330 280 290 300 310 320 330 pF1KB6 VHEYVLYSEMLMGVMKRRDQIQAELDSKVEVLTYKKADTDLLPEEIGKLEDKVECANNAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 VHEYVLYSEMLMGVMKRRDQIQAELDSKVEVLTYKKADTDLLPEEIGKLEDKVECANNAL 340 350 360 370 380 390 340 350 360 370 380 pF1KB6 KADWERWKQNMQNDIKLAFTDMAEENIHYYEQCLATWESFLTSQTNLHLEEASEDKP ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 KADWERWKQNMQNDIKLAFTDMAEENIHYYEQCLATWESFLTSQTNLHLEEASEDKP 400 410 420 430 440 450 >>CCDS756.2 SNX7 gene_id:51375|Hs108|chr1 (396 aa) initn: 1570 init1: 1570 opt: 1570 Z-score: 1732.8 bits: 329.4 E(32554): 3.4e-90 Smith-Waterman score: 2072; 85.8% identity (85.8% similar) in 387 aa overlap (1-387:65-396) 10 20 30 pF1KB6 MDMNSFSPMMPTSPLSMINQIKFEDEPDLK :::::::::::::::::::::::::::::: CCDS75 SGSSALLQAEVLDLDEDEDDLEVFSKDASLMDMNSFSPMMPTSPLSMINQIKFEDEPDLK 40 50 60 70 80 90 40 50 60 70 80 90 pF1KB6 DLFITVDEPESHVTTIETFITYRIITKTSRGEFDSSEFEVRRRYQDFLWLKGKLEEAHPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 DLFITVDEPESHVTTIETFITYRIITKTSRGEFDSSEFEVRRRYQDFLWLKGKLEEAHPT 100 110 120 130 140 150 100 110 120 130 140 150 pF1KB6 LIIPPLPEKFIVKGMVERFNDDFIETRRKALHKFLNRIADHPTLTFNEDFKIFLTAQAWE :::: : CCDS75 LIIP-------------------------------------------------------E 160 170 180 190 200 210 pF1KB6 LSSHKKQGPGLLSRMGQTVRAVASSMRGVKNRPEEFMEMNNFIELFSQKINLIDKISQRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 LSSHKKQGPGLLSRMGQTVRAVASSMRGVKNRPEEFMEMNNFIELFSQKINLIDKISQRI 160 170 180 190 200 210 220 230 240 250 260 270 pF1KB6 YKEEREYFDEMKEYGPIHILWSASEEDLVDTLKDVASCIDRCCKATEKRMSGLSEALLPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 YKEEREYFDEMKEYGPIHILWSASEEDLVDTLKDVASCIDRCCKATEKRMSGLSEALLPV 220 230 240 250 260 270 280 290 300 310 320 330 pF1KB6 VHEYVLYSEMLMGVMKRRDQIQAELDSKVEVLTYKKADTDLLPEEIGKLEDKVECANNAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 VHEYVLYSEMLMGVMKRRDQIQAELDSKVEVLTYKKADTDLLPEEIGKLEDKVECANNAL 280 290 300 310 320 330 340 350 360 370 380 pF1KB6 KADWERWKQNMQNDIKLAFTDMAEENIHYYEQCLATWESFLTSQTNLHLEEASEDKP ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS75 KADWERWKQNMQNDIKLAFTDMAEENIHYYEQCLATWESFLTSQTNLHLEEASEDKP 340 350 360 370 380 390 >>CCDS43865.1 SNX30 gene_id:401548|Hs108|chr9 (437 aa) initn: 1244 init1: 608 opt: 1274 Z-score: 1406.7 bits: 269.2 E(32554): 4.9e-72 Smith-Waterman score: 1274; 49.3% identity (81.5% similar) in 363 aa overlap (11-371:68-427) 10 20 30 pF1KB6 MDMNSFSPMMPTSPLSMINQIKFEDEPD--LKDLFITVDE :.: :..:.....:. : .:::. ::. CCDS43 TPSPDLLMARSFGDKDLILPNGGTPAGTSSPASSSSLLNRLQLDDDIDGETRDLFVIVDD 40 50 60 70 80 90 40 50 60 70 80 90 pF1KB6 PESHVTTIETFITYRIITKTSRGEFDSSEFEVRRRYQDFLWLKGKLEEAHPTLIIPPLPE :..:: :.::.::::: ::..: ::: :. :::::::: ::..::::..:: .:::::: CCDS43 PKKHVCTMETYITYRITTKSTRVEFDLPEYSVRRRYQDFDWLRSKLEESQPTHLIPPLPE 100 110 120 130 140 150 100 110 120 130 140 150 pF1KB6 KFIVKGMVERFNDDFIETRRKALHKFLNRIADHPTLTFNEDFKIFLTAQAWELSSHKKQG ::.:::.:.::...:.::::::: :::.::.:::.:.::: :.:::::. .:...:::: CCDS43 KFVVKGVVDRFSEEFVETRRKALDKFLKRITDHPVLSFNEHFNIFLTAK--DLNAYKKQG 160 170 180 190 200 210 160 170 180 190 200 210 pF1KB6 PGLLSRMGQTVRAVASSMRGVKNRPEEFMEMNNFIELFSQKINLIDKISQRIYKEEREYF .::.:::..:. :..... ...:: :: ...... :. :.. ::.:.::: ::: ::. CCDS43 IALLTRMGESVKHVTGGYK-LRTRPLEFAAIGDYLDTFALKLGTIDRIAQRIIKEEIEYL 220 230 240 250 260 270 220 230 240 250 260 270 pF1KB6 DEMKEYGPIHILWSASEEDLVDTLKDVASCIDRCCKATEKRMSGLSEALLPVVHEYVLYS :..::::.. ::: : .:.. :. :..:: : : :. . ..: .:::..::.::: CCDS43 VELREYGPVYSTWSALEGELAEPLEGVSACIGNCSTALEELTDDMTEDFLPVLREYILYS 280 290 300 310 320 330 280 290 300 310 320 330 pF1KB6 EMLMGVMKRRDQIQAELDSKVEVLTYKKADTDLLPEEIGKLEDKVECANNALKADWERWK . . .:.:.:::.::: ..:.:... .: : .: .. : .:..:: : :::: :::. CCDS43 DSMKSVLKKRDQVQAEYEAKLEAVALRKEDRPKVPADVEKCQDRMECFNADLKADMERWQ 340 350 360 370 380 390 340 350 360 370 380 pF1KB6 QNMQNDIKLAFTDMAEENIHYYEQCLATWESFLTSQTNLHLEEASEDKP .: ..:.. . ::..::.:::.:: .:::.. CCDS43 NNKRQDFRQLLMGMADKNIQYYEKCLMAWESIIPLLQEKQEAK 400 410 420 430 >>CCDS3032.1 SNX4 gene_id:8723|Hs108|chr3 (450 aa) initn: 279 init1: 113 opt: 330 Z-score: 368.4 bits: 77.2 E(32554): 3.4e-14 Smith-Waterman score: 339; 25.7% identity (60.5% similar) in 296 aa overlap (29-312:55-345) 10 20 30 40 50 pF1KB6 MDMNSFSPMMPTSPLSMINQIKFEDEPDLKDLFITVDEPESH-----VTTIETFITYR :: . :.:.: :.. .. ::. .: CCDS30 AGLGAAVGKEAEGAGEESSGVDTMTHNNFWLKKIEISVSEAEKRTGRNAMNMQETYTAYL 30 40 50 60 70 80 60 70 80 90 100 pF1KB6 IITKTSRGEFDSSEFE--VRRRYQDFLWLKGKLEEAHPTLIIPPLPEK---FIVKGM-VE : :.. . .: . . :::..: :.. : .: ...:::::: :. . . .. CCDS30 IETRSVEHTDGQSVLTDSLWRRYSEFELLRSYLLVYYPHIVVPPLPEKRAEFVWHKLSAD 90 100 110 120 130 140 110 120 130 140 150 160 pF1KB6 RFNDDFIETRRKALHKFLNRIADHPTLTFNEDFKIFLTAQA-WELSSHKKQGPGLLSRMG .. ::.: :: .:..:: :::.:: : .. : .::: .. :. . .. :. . CCDS30 NMDPDFVERRRIGLENFLLRIASHPILCRDKIFYLFLTQEGNWKETVNET---GFQLKAD 150 160 170 180 190 200 170 180 190 200 210 220 pF1KB6 QTVRAVASSMRGVKNRPEEFMEMNNFIELFSQKINLIDKISQRIYKEEREYFDEMKEYGP . ..:. ...: ::: ..: ..... . ... :. . .. :. . . .:: CCDS30 SRLKALNATFR-VKNPDKRFTDLKHYSDELQSVISHLLRVRARVADRLYGVYKVHGNYGR 210 220 230 240 250 260 230 240 250 260 270 280 pF1KB6 IHILWSASEEDLVDTLKDVASCIDRCCKATEKRMSGLSEALLPVVHEYVLYSEMLMGVMK . ::: :... : :.... .: .. . . : ..::..:.: : .: . CCDS30 VFSEWSAIEKEMGDGLQSAGHHMDVYASSIDDILED-EEHYADQLKEYLFYAEALRAVCR 270 280 290 300 310 290 300 310 320 330 340 pF1KB6 RRDQIQAELDSKVEVLTYKKADTDLLPEEIGKLEDKVECANNALKADWERWKQNMQNDIK ... .: .:. .. :. :: . . : CCDS30 KHELMQYDLEMAAQDLASKKQQCEELVTGTVRTFSLKGMTTKLFGQETPEQREARIKVLE 320 330 340 350 360 370 >>CCDS32268.1 SNX1 gene_id:6642|Hs108|chr15 (457 aa) initn: 213 init1: 109 opt: 313 Z-score: 349.6 bits: 73.7 E(32554): 3.7e-13 Smith-Waterman score: 325; 23.4% identity (56.2% similar) in 397 aa overlap (7-371:63-450) 10 20 30 pF1KB6 MDMNSFSPMMPTSPLSMINQIKFEDEPDLKDLFITV . ..: . : : :. :.. . .::: CCDS32 EPEAGDSDTEGEDIFTGAAVVSKHQSPKITTSLLPINNGSKENGIHEEQDQEPQDLFAG- 40 50 60 70 80 90 40 50 60 70 80 90 pF1KB6 DEPESHVTTIETFITYRIITKTSRGEFDSSEFEVRRRYQDFLWLKGKLEEAHPT--LIIP ......:.. :.:: : :..: :.::..::: : :: : : .:.: CCDS32 -------DGMNAYVAYKVTTQTSLPLFRSKQFAVKRRFSDFLGLYEKLSEKHSQNGFIVP 100 110 120 130 140 100 110 120 130 140 pF1KB6 PLPEKFIVKGM--VERFNDD-----FIETRRKALHKFLNRIADHPTLTFNEDFKIFLTAQ : ::: .. :: :. ..: :.: :: ::...:.::..:::. . : . :: . CCDS32 PPPEKSLI-GMTKVKVGKEDSSSAEFLEKRRAALERYLQRIVNHPTMLQDPDVREFLEKE 150 160 170 180 190 200 150 160 170 180 190 200 pF1KB6 AWE--LSSHKKQGPGLLSRMGQTVRAVASSMRGVKNRPEEFMEMNNFIELFSQKINLIDK .... .: :::. ..... ::.. ... : : . .: :.. . CCDS32 ELPRAVGTQTLSGAGLLKMFNKATDAVSKMTIKMNESDIWFEEKLQEVECEEQRLRKLHA 210 220 230 240 250 260 210 220 230 240 250 260 pF1KB6 ISQRIYKEEREYFDEMKEYGPIHILWSASEED--LVDTLKDVASCIDRCCKATEKRMSGL . . . ....: . ... . ..::.. : .:...: .. . ... .. CCDS32 VVETLVNHRKELALNTAQFAKSLAMLGSSEDNTALSRALSQLAEVEEKIEQLHQEQANND 270 280 290 300 310 320 270 280 290 300 310 pF1KB6 SEALLPVVHEYVLYSEMLMGVMKRRDQI-QAELDSKVEVLTYKKADTDLL----PEEIGK : .. .:. .. ... .: . : :... . ..:.. :: :... . CCDS32 FFLLAELLSDYIRLLAIVRAAFDQRMKTWQRWQDAQATLQKKREAEARLLWANKPDKLQQ 330 340 350 360 370 380 320 330 340 350 360 pF1KB6 LEDKV---ECANNALKADWERWKQNMQNDI----KLAFTDMAEENIHYYE------QCLA .:.. : . . :.:: . ..... : :. .. :.: : : :: CCDS32 AKDEILEWESRVTQYERDFERISTVVRKEVIRFEKEKSKDFKNHVIKYLETLLYSQQQLA 390 400 410 420 430 440 370 380 pF1KB6 T-WESFLTSQTNLHLEEASEDKP ::.:: CCDS32 KYWEAFLPEAKAIS 450 >>CCDS64234.1 SNX2 gene_id:6643|Hs108|chr5 (402 aa) initn: 327 init1: 163 opt: 307 Z-score: 343.8 bits: 72.4 E(32554): 7.9e-13 Smith-Waterman score: 355; 24.6% identity (58.7% similar) in 341 aa overlap (20-346:13-348) 10 20 30 40 50 60 pF1KB6 MDMNSFSPMMPTSPLSMINQIKFEDEPDLKDLFITVDEPESHVTTIETFITYRIITKTSR .:. : . :. :. : :..::. ......::. :::: CCDS64 MSAPVIFDRSREEIEEEANGDIFDIEIGVSDPEKVGDGMNAYMAYRVTTKTSL 10 20 30 40 50 70 80 90 100 110 pF1KB6 GEFDSSEFEVRRRYQDFLWLKGKLEEA--HPTLIIPPLPEKFIVKGMV-------ERFND . :..::: :.::..::: :..:: : :.:: ::: :: ::. . . CCDS64 SMFSKSEFSVKRRFSDFLGLHSKLASKYLHVGYIVPPAPEKSIV-GMTKVKVGKEDSSST 60 70 80 90 100 110 120 130 140 150 160 pF1KB6 DFIETRRKALHKFLNRIADHPTLTFNEDFKIFLTAQAWE--LSSHKKQGPGLLSRMGQTV .:.: :: ::...:.: . :::: . :.. :: .. .... .: :.: ..... CCDS64 EFVEKRRAALERYLQRTVKHPTLLQDPDLRQFLESSELPRAVNTQALSGAGILRMVNKAA 120 130 140 150 160 170 170 180 190 200 210 220 pF1KB6 RAVASSMRGVKNRPEEFMEMNNFIELFSQKINLIDKISQRIYKEEREYFDEMKEYGPIHI :: . ... : : .. .: ..:.. . . . ...: . .. CCDS64 DAVNKMTIKMNESDAWFEEKQQQFENLDQQLRKLHVSVEALVCHRKELSANTAAFAKSAA 180 190 200 210 220 230 230 240 250 260 270 280 pF1KB6 LWSASEED--LVDTLKDVASCIDRCCKATEKRMSGLSEALLPVVHEYVLYSEMLMGVMKR . . ::. : .:...: .. . ... . . .. .:. . ::. . CCDS64 MLGNSEDHTALSRALSQLAEVEEKIDQLHQEQAFADFYMFSELLSDYIRLIAAVKGVFDH 240 250 260 270 280 290 290 300 310 320 330 340 pF1KB6 RDQI-QAELDSKVEVLTYKKADTDLLPEEIGKLEDKVECANNALKADWERWKQNMQNDIK : . : :... .: ..:.. .. ... ::.. :.: .. .:: :. . :.. CCDS64 RMKCWQKWEDAQITLLKKREAEAKMM---VANKPDKIQQAKNEIR-EWEAKVQQGERDFE 300 310 320 330 340 350 360 370 380 pF1KB6 LAFTDMAEENIHYYEQCLATWESFLTSQTNLHLEEASEDKP CCDS64 QISKTIRKEVGRFEKERVKDFKTVIIKYLESLVQTQQQLIKYWEAFLPEAKAIA 350 360 370 380 390 400 >>CCDS34217.1 SNX2 gene_id:6643|Hs108|chr5 (519 aa) initn: 327 init1: 163 opt: 307 Z-score: 342.2 bits: 72.5 E(32554): 9.7e-13 Smith-Waterman score: 355; 24.6% identity (58.7% similar) in 341 aa overlap (20-346:130-465) 10 20 30 40 pF1KB6 MDMNSFSPMMPTSPLSMINQIKFEDEPDLKDLFITVDEPESHVTTIETF .:. : . :. :. : :..::. .... CCDS34 VTPVTPTTLIAPRIESKSMSAPVIFDRSREEIEEEANGDIFDIEIGVSDPEKVGDGMNAY 100 110 120 130 140 150 50 60 70 80 90 100 pF1KB6 ITYRIITKTSRGEFDSSEFEVRRRYQDFLWLKGKLEEA--HPTLIIPPLPEKFIVKGMV- ..::. :::: . :..::: :.::..::: :..:: : :.:: ::: :: ::. CCDS34 MAYRVTTKTSLSMFSKSEFSVKRRFSDFLGLHSKLASKYLHVGYIVPPAPEKSIV-GMTK 160 170 180 190 200 210 110 120 130 140 150 pF1KB6 ------ERFNDDFIETRRKALHKFLNRIADHPTLTFNEDFKIFLTAQAWE--LSSHKKQG . . .:.: :: ::...:.: . :::: . :.. :: .. .... .: CCDS34 VKVGKEDSSSTEFVEKRRAALERYLQRTVKHPTLLQDPDLRQFLESSELPRAVNTQALSG 220 230 240 250 260 270 160 170 180 190 200 210 pF1KB6 PGLLSRMGQTVRAVASSMRGVKNRPEEFMEMNNFIELFSQKINLIDKISQRIYKEEREYF :.: ..... :: . ... : : .. .: ..:.. . . . ...: CCDS34 AGILRMVNKAADAVNKMTIKMNESDAWFEEKQQQFENLDQQLRKLHVSVEALVCHRKELS 280 290 300 310 320 330 220 230 240 250 260 270 pF1KB6 DEMKEYGPIHILWSASEED--LVDTLKDVASCIDRCCKATEKRMSGLSEALLPVVHEYVL . .. . . ::. : .:...: .. . ... . . .. .:. CCDS34 ANTAAFAKSAAMLGNSEDHTALSRALSQLAEVEEKIDQLHQEQAFADFYMFSELLSDYIR 340 350 360 370 380 390 280 290 300 310 320 330 pF1KB6 YSEMLMGVMKRRDQI-QAELDSKVEVLTYKKADTDLLPEEIGKLEDKVECANNALKADWE . ::. .: . : :... .: ..:.. .. ... ::.. :.: .. .:: CCDS34 LIAAVKGVFDHRMKCWQKWEDAQITLLKKREAEAKMM---VANKPDKIQQAKNEIR-EWE 400 410 420 430 440 450 340 350 360 370 380 pF1KB6 RWKQNMQNDIKLAFTDMAEENIHYYEQCLATWESFLTSQTNLHLEEASEDKP :. . :.. CCDS34 AKVQQGERDFEQISKTIRKEVGRFEKERVKDFKTVIIKYLESLVQTQQQLIKYWEAFLPE 460 470 480 490 500 510 >>CCDS32266.1 SNX1 gene_id:6642|Hs108|chr15 (522 aa) initn: 267 init1: 145 opt: 293 Z-score: 326.8 bits: 69.7 E(32554): 7e-12 Smith-Waterman score: 355; 23.5% identity (57.4% similar) in 392 aa overlap (12-371:125-515) 10 20 30 40 pF1KB6 MDMNSFSPMMPTSPLSMINQIKFEDEPDLKDLFITVDEPES ..: .... :.. : :: . . .::. CCDS32 ELSLDSTQNNQKKVLAKTLISLPPQEATNSSKPQPTYEELEEEEQEDQFDLTVGITDPEK 100 110 120 130 140 150 50 60 70 80 90 pF1KB6 HVTTIETFITYRIITKTSRGEFDSSEFEVRRRYQDFLWLKGKLEEAHPT--LIIPPLPEK ......:.. :.:: : :..: :.::..::: : :: : : .:.:: ::: CCDS32 IGDGMNAYVAYKVTTQTSLPLFRSKQFAVKRRFSDFLGLYEKLSEKHSQNGFIVPPPPEK 160 170 180 190 200 210 100 110 120 130 140 150 pF1KB6 FIVKGM--VERFNDD-----FIETRRKALHKFLNRIADHPTLTFNEDFKIFLTAQAWE-- .. :: :. ..: :.: :: ::...:.::..:::. . : . :: . CCDS32 SLI-GMTKVKVGKEDSSSAEFLEKRRAALERYLQRIVNHPTMLQDPDVREFLEKEELPRA 220 230 240 250 260 270 160 170 180 190 200 210 pF1KB6 LSSHKKQGPGLLSRMGQTVRAVASSMRGVKNRPEEFMEMNNFIELFSQKINLIDKISQRI .... .: :::. ..... ::.. ... : : . .: :.. . . . . CCDS32 VGTQTLSGAGLLKMFNKATDAVSKMTIKMNESDIWFEEKLQEVECEEQRLRKLHAVVETL 280 290 300 310 320 330 220 230 240 250 260 pF1KB6 YKEEREYFDEMKEYGPIHILWSASEED--LVDTLKDVASCIDRCCKATEKRMSGLSEALL ....: . ... . ..::.. : .:...: .. . ... .. : CCDS32 VNHRKELALNTAQFAKSLAMLGSSEDNTALSRALSQLAEVEEKIEQLHQEQANNDFFLLA 340 350 360 370 380 390 270 280 290 300 310 320 pF1KB6 PVVHEYVLYSEMLMGVMKRRDQI-QAELDSKVEVLTYKKADTDLL----PEEIGKLEDKV .. .:. .. ... .: . : :... . ..:.. :: :... . .:.. CCDS32 ELLSDYIRLLAIVRAAFDQRMKTWQRWQDAQATLQKKREAEARLLWANKPDKLQQAKDEI 400 410 420 430 440 450 330 340 350 360 pF1KB6 ---ECANNALKADWERWKQNMQNDI----KLAFTDMAEENIHYYE------QCLAT-WES : . . :.:: . ..... : :. .. :.: : : :: ::. CCDS32 LEWESRVTQYERDFERISTVVRKEVIRFEKEKSKDFKNHVIKYLETLLYSQQQLAKYWEA 460 470 480 490 500 510 370 380 pF1KB6 FLTSQTNLHLEEASEDKP :: CCDS32 FLPEAKAIS 520 >>CCDS58371.1 SNX1 gene_id:6642|Hs108|chr15 (557 aa) initn: 267 init1: 145 opt: 293 Z-score: 326.4 bits: 69.7 E(32554): 7.4e-12 Smith-Waterman score: 346; 22.4% identity (58.1% similar) in 384 aa overlap (12-374:125-504) 10 20 30 40 pF1KB6 MDMNSFSPMMPTSPLSMINQIKFEDEPDLKDLFITVDEPES ..: .... :.. : :: . . .::. CCDS58 ELSLDSTQNNQKKVLAKTLISLPPQEATNSSKPQPTYEELEEEEQEDQFDLTVGITDPEK 100 110 120 130 140 150 50 60 70 80 90 pF1KB6 HVTTIETFITYRIITKTSRGEFDSSEFEVRRRYQDFLWLKGKLEEAHPT--LIIPPLPEK ......:.. :.:: : :..: :.::..::: : :: : : .:.:: ::: CCDS58 IGDGMNAYVAYKVTTQTSLPLFRSKQFAVKRRFSDFLGLYEKLSEKHSQNGFIVPPPPEK 160 170 180 190 200 210 100 110 120 130 140 150 pF1KB6 FIVKGM--VERFNDD-----FIETRRKALHKFLNRIADHPTLTFNEDFKIFLTAQAWE-- .. :: :. ..: :.: :: ::...:.::..:::. . : . :: . CCDS58 SLI-GMTKVKVGKEDSSSAEFLEKRRAALERYLQRIVNHPTMLQDPDVREFLEKEELPRA 220 230 240 250 260 270 160 170 180 190 200 210 pF1KB6 LSSHKKQGPGLLSRMGQTVRAVASSMRGVKNRPEEFMEMNNFIELFSQKINLIDKISQRI .... .: :::. ..... ::.. ... : : . .: :.. . . . . CCDS58 VGTQTLSGAGLLKMFNKATDAVSKMTIKMNESDIWFEEKLQEVECEEQRLRKLHAVVETL 280 290 300 310 320 330 220 230 240 250 260 pF1KB6 YKEEREYFDEMKEYGPIHILWSASEED--LVDTLKDVASCIDRCCKATEKRMSGLSEALL ....: . ... . ..::.. : .:...: .. . ... .. : CCDS58 VNHRKELALNTAQFAKSLAMLGSSEDNTALSRALSQLAEVEEKIEQLHQEQANNDFFLLA 340 350 360 370 380 390 270 280 290 300 310 320 pF1KB6 PVVHEYVLYSEMLMGVMKRRDQI-QAELDSKVEVLTYKKADTDLL----PEEIGKLEDKV .. .:. .. ... .: . : :... . ..:.. :: :... . .:.. CCDS58 ELLSDYIRLLAIVRAAFDQRMKTWQRWQDAQATLQKKREAEARLLWANKPDKLQQAKDEI 400 410 420 430 440 450 330 340 350 360 370 380 pF1KB6 ---ECANNALKADWERWKQNMQNDIKLAFTDMAEENIHYYEQCLATWESFLTSQTNLHLE : . . :.:: . ..... . : :.. . .. . :..: :: CCDS58 LEWESRVTQYERDFERISTVVRKEV-IRFEK--EKSKDFKNHVIKYLETLLYSQQQAGEQ 460 470 480 490 500 510 pF1KB6 EASEDKP CCDS58 LGIRSGILLTKKLPRYSKFFSTVHKFCAAASLWKWGFFLSAYLSYLF 520 530 540 550 387 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 04:20:03 2016 done: Sat Nov 5 04:20:03 2016 Total Scan time: 2.740 Total Display time: 0.070 Function used was FASTA [36.3.4 Apr, 2011]