FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6522, 387 aa 1>>>pF1KB6522 387 - 387 aa - 387 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.3952+/-0.000401; mu= 17.4912+/- 0.025 mean_var=96.2942+/-20.584, 0's: 0 Z-trim(112.3): 114 B-trim: 176 in 1/52 Lambda= 0.130700 statistics sampled from 21113 (21240) to 21113 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.614), E-opt: 0.2 (0.249), width: 16 Scan time: 8.380 The best scores are: opt bits E(85289) XP_016856915 (OMIM: 614904) PREDICTED: sorting nex ( 387) 2565 494.3 2e-139 XP_016856914 (OMIM: 614904) PREDICTED: sorting nex ( 387) 2565 494.3 2e-139 XP_011539866 (OMIM: 614904) PREDICTED: sorting nex ( 387) 2565 494.3 2e-139 XP_016856916 (OMIM: 614904) PREDICTED: sorting nex ( 387) 2565 494.3 2e-139 XP_006710741 (OMIM: 614904) PREDICTED: sorting nex ( 387) 2565 494.3 2e-139 NP_057060 (OMIM: 614904) sorting nexin-7 isoform a ( 451) 2565 494.4 2.2e-139 XP_016856917 (OMIM: 614904) PREDICTED: sorting nex ( 336) 2045 396.2 5.9e-110 XP_006710740 (OMIM: 614904) PREDICTED: sorting nex ( 422) 2045 396.3 7e-110 NP_689424 (OMIM: 614904) sorting nexin-7 isoform b ( 396) 1570 306.7 6.1e-83 NP_003785 (OMIM: 605931) sorting nexin-4 [Homo sap ( 450) 330 73.0 1.6e-12 NP_683758 (OMIM: 601272) sorting nexin-1 isoform b ( 457) 313 69.8 1.5e-11 NP_001265128 (OMIM: 605929) sorting nexin-2 isofor ( 402) 307 68.6 3e-11 NP_003091 (OMIM: 605929) sorting nexin-2 isoform 1 ( 519) 307 68.7 3.6e-11 XP_005254668 (OMIM: 601272) PREDICTED: sorting nex ( 399) 300 67.3 7.5e-11 NP_003090 (OMIM: 601272) sorting nexin-1 isoform a ( 522) 293 66.0 2.3e-10 NP_001229862 (OMIM: 601272) sorting nexin-1 isofor ( 557) 293 66.1 2.4e-10 NP_003786 (OMIM: 605930) sorting nexin-3 isoform a ( 162) 245 56.5 5.3e-08 XP_016862903 (OMIM: 605931) PREDICTED: sorting nex ( 482) 243 56.6 1.5e-07 NP_037478 (OMIM: 300883) sorting nexin-12 isoform ( 162) 236 54.8 1.7e-07 NP_001243114 (OMIM: 300883) sorting nexin-12 isofo ( 162) 236 54.8 1.7e-07 NP_001243117 (OMIM: 300883) sorting nexin-12 isofo ( 158) 217 51.2 2e-06 NP_001287858 (OMIM: 605930) sorting nexin-3 isofor ( 140) 213 50.4 3.1e-06 XP_011522999 (OMIM: 614906) PREDICTED: sorting nex ( 270) 202 48.6 2.1e-05 NP_037455 (OMIM: 614906) sorting nexin-11 isoform ( 270) 202 48.6 2.1e-05 NP_689450 (OMIM: 614906) sorting nexin-11 isoform ( 270) 202 48.6 2.1e-05 XP_005257317 (OMIM: 614906) PREDICTED: sorting nex ( 270) 202 48.6 2.1e-05 XP_005257319 (OMIM: 614906) PREDICTED: sorting nex ( 262) 199 48.0 3e-05 NP_001317249 (OMIM: 614906) sorting nexin-11 isofo ( 262) 199 48.0 3e-05 NP_689413 (OMIM: 605937) sorting nexin-5 isoform a ( 404) 179 44.4 0.00056 NP_055241 (OMIM: 605937) sorting nexin-5 isoform a ( 404) 179 44.4 0.00056 XP_016867573 (OMIM: 614905) PREDICTED: sorting nex ( 412) 172 43.1 0.0014 XP_016867572 (OMIM: 614905) PREDICTED: sorting nex ( 412) 172 43.1 0.0014 XP_011513632 (OMIM: 614905) PREDICTED: sorting nex ( 451) 172 43.2 0.0015 XP_011513631 (OMIM: 614905) PREDICTED: sorting nex ( 457) 172 43.2 0.0015 NP_037453 (OMIM: 614905) sorting nexin-8 [Homo sap ( 465) 172 43.2 0.0015 NP_037454 (OMIM: 614780,615085) sorting nexin-10 i ( 201) 162 40.9 0.0031 XP_006715775 (OMIM: 614780,615085) PREDICTED: sort ( 201) 162 40.9 0.0031 NP_001305128 (OMIM: 614780,615085) sorting nexin-1 ( 201) 162 40.9 0.0031 NP_001186764 (OMIM: 614780,615085) sorting nexin-1 ( 201) 162 40.9 0.0031 NP_001186766 (OMIM: 614780,615085) sorting nexin-1 ( 198) 161 40.7 0.0035 XP_016867575 (OMIM: 614780,615085) PREDICTED: sort ( 227) 161 40.8 0.0039 NP_001305127 (OMIM: 614780,615085) sorting nexin-1 ( 227) 161 40.8 0.0039 XP_016867574 (OMIM: 614780,615085) PREDICTED: sort ( 227) 161 40.8 0.0039 XP_016867576 (OMIM: 614780,615085) PREDICTED: sort ( 227) 161 40.8 0.0039 XP_011534188 (OMIM: 605952) PREDICTED: sorting nex ( 501) 160 41.0 0.0078 XP_005267072 (OMIM: 605952) PREDICTED: sorting nex ( 588) 160 41.0 0.0087 NP_057308 (OMIM: 605952) sorting nexin-9 [Homo sap ( 595) 160 41.0 0.0088 >>XP_016856915 (OMIM: 614904) PREDICTED: sorting nexin-7 (387 aa) initn: 2565 init1: 2565 opt: 2565 Z-score: 2624.1 bits: 494.3 E(85289): 2e-139 Smith-Waterman score: 2565; 100.0% identity (100.0% similar) in 387 aa overlap (1-387:1-387) 10 20 30 40 50 60 pF1KB6 MDMNSFSPMMPTSPLSMINQIKFEDEPDLKDLFITVDEPESHVTTIETFITYRIITKTSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MDMNSFSPMMPTSPLSMINQIKFEDEPDLKDLFITVDEPESHVTTIETFITYRIITKTSR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 GEFDSSEFEVRRRYQDFLWLKGKLEEAHPTLIIPPLPEKFIVKGMVERFNDDFIETRRKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GEFDSSEFEVRRRYQDFLWLKGKLEEAHPTLIIPPLPEKFIVKGMVERFNDDFIETRRKA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 LHKFLNRIADHPTLTFNEDFKIFLTAQAWELSSHKKQGPGLLSRMGQTVRAVASSMRGVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LHKFLNRIADHPTLTFNEDFKIFLTAQAWELSSHKKQGPGLLSRMGQTVRAVASSMRGVK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 NRPEEFMEMNNFIELFSQKINLIDKISQRIYKEEREYFDEMKEYGPIHILWSASEEDLVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NRPEEFMEMNNFIELFSQKINLIDKISQRIYKEEREYFDEMKEYGPIHILWSASEEDLVD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 TLKDVASCIDRCCKATEKRMSGLSEALLPVVHEYVLYSEMLMGVMKRRDQIQAELDSKVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TLKDVASCIDRCCKATEKRMSGLSEALLPVVHEYVLYSEMLMGVMKRRDQIQAELDSKVE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 VLTYKKADTDLLPEEIGKLEDKVECANNALKADWERWKQNMQNDIKLAFTDMAEENIHYY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VLTYKKADTDLLPEEIGKLEDKVECANNALKADWERWKQNMQNDIKLAFTDMAEENIHYY 310 320 330 340 350 360 370 380 pF1KB6 EQCLATWESFLTSQTNLHLEEASEDKP ::::::::::::::::::::::::::: XP_016 EQCLATWESFLTSQTNLHLEEASEDKP 370 380 >>XP_016856914 (OMIM: 614904) PREDICTED: sorting nexin-7 (387 aa) initn: 2565 init1: 2565 opt: 2565 Z-score: 2624.1 bits: 494.3 E(85289): 2e-139 Smith-Waterman score: 2565; 100.0% identity (100.0% similar) in 387 aa overlap (1-387:1-387) 10 20 30 40 50 60 pF1KB6 MDMNSFSPMMPTSPLSMINQIKFEDEPDLKDLFITVDEPESHVTTIETFITYRIITKTSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MDMNSFSPMMPTSPLSMINQIKFEDEPDLKDLFITVDEPESHVTTIETFITYRIITKTSR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 GEFDSSEFEVRRRYQDFLWLKGKLEEAHPTLIIPPLPEKFIVKGMVERFNDDFIETRRKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GEFDSSEFEVRRRYQDFLWLKGKLEEAHPTLIIPPLPEKFIVKGMVERFNDDFIETRRKA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 LHKFLNRIADHPTLTFNEDFKIFLTAQAWELSSHKKQGPGLLSRMGQTVRAVASSMRGVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LHKFLNRIADHPTLTFNEDFKIFLTAQAWELSSHKKQGPGLLSRMGQTVRAVASSMRGVK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 NRPEEFMEMNNFIELFSQKINLIDKISQRIYKEEREYFDEMKEYGPIHILWSASEEDLVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NRPEEFMEMNNFIELFSQKINLIDKISQRIYKEEREYFDEMKEYGPIHILWSASEEDLVD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 TLKDVASCIDRCCKATEKRMSGLSEALLPVVHEYVLYSEMLMGVMKRRDQIQAELDSKVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TLKDVASCIDRCCKATEKRMSGLSEALLPVVHEYVLYSEMLMGVMKRRDQIQAELDSKVE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 VLTYKKADTDLLPEEIGKLEDKVECANNALKADWERWKQNMQNDIKLAFTDMAEENIHYY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VLTYKKADTDLLPEEIGKLEDKVECANNALKADWERWKQNMQNDIKLAFTDMAEENIHYY 310 320 330 340 350 360 370 380 pF1KB6 EQCLATWESFLTSQTNLHLEEASEDKP ::::::::::::::::::::::::::: XP_016 EQCLATWESFLTSQTNLHLEEASEDKP 370 380 >>XP_011539866 (OMIM: 614904) PREDICTED: sorting nexin-7 (387 aa) initn: 2565 init1: 2565 opt: 2565 Z-score: 2624.1 bits: 494.3 E(85289): 2e-139 Smith-Waterman score: 2565; 100.0% identity (100.0% similar) in 387 aa overlap (1-387:1-387) 10 20 30 40 50 60 pF1KB6 MDMNSFSPMMPTSPLSMINQIKFEDEPDLKDLFITVDEPESHVTTIETFITYRIITKTSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MDMNSFSPMMPTSPLSMINQIKFEDEPDLKDLFITVDEPESHVTTIETFITYRIITKTSR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 GEFDSSEFEVRRRYQDFLWLKGKLEEAHPTLIIPPLPEKFIVKGMVERFNDDFIETRRKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 GEFDSSEFEVRRRYQDFLWLKGKLEEAHPTLIIPPLPEKFIVKGMVERFNDDFIETRRKA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 LHKFLNRIADHPTLTFNEDFKIFLTAQAWELSSHKKQGPGLLSRMGQTVRAVASSMRGVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LHKFLNRIADHPTLTFNEDFKIFLTAQAWELSSHKKQGPGLLSRMGQTVRAVASSMRGVK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 NRPEEFMEMNNFIELFSQKINLIDKISQRIYKEEREYFDEMKEYGPIHILWSASEEDLVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 NRPEEFMEMNNFIELFSQKINLIDKISQRIYKEEREYFDEMKEYGPIHILWSASEEDLVD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 TLKDVASCIDRCCKATEKRMSGLSEALLPVVHEYVLYSEMLMGVMKRRDQIQAELDSKVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TLKDVASCIDRCCKATEKRMSGLSEALLPVVHEYVLYSEMLMGVMKRRDQIQAELDSKVE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 VLTYKKADTDLLPEEIGKLEDKVECANNALKADWERWKQNMQNDIKLAFTDMAEENIHYY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 VLTYKKADTDLLPEEIGKLEDKVECANNALKADWERWKQNMQNDIKLAFTDMAEENIHYY 310 320 330 340 350 360 370 380 pF1KB6 EQCLATWESFLTSQTNLHLEEASEDKP ::::::::::::::::::::::::::: XP_011 EQCLATWESFLTSQTNLHLEEASEDKP 370 380 >>XP_016856916 (OMIM: 614904) PREDICTED: sorting nexin-7 (387 aa) initn: 2565 init1: 2565 opt: 2565 Z-score: 2624.1 bits: 494.3 E(85289): 2e-139 Smith-Waterman score: 2565; 100.0% identity (100.0% similar) in 387 aa overlap (1-387:1-387) 10 20 30 40 50 60 pF1KB6 MDMNSFSPMMPTSPLSMINQIKFEDEPDLKDLFITVDEPESHVTTIETFITYRIITKTSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MDMNSFSPMMPTSPLSMINQIKFEDEPDLKDLFITVDEPESHVTTIETFITYRIITKTSR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 GEFDSSEFEVRRRYQDFLWLKGKLEEAHPTLIIPPLPEKFIVKGMVERFNDDFIETRRKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GEFDSSEFEVRRRYQDFLWLKGKLEEAHPTLIIPPLPEKFIVKGMVERFNDDFIETRRKA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 LHKFLNRIADHPTLTFNEDFKIFLTAQAWELSSHKKQGPGLLSRMGQTVRAVASSMRGVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LHKFLNRIADHPTLTFNEDFKIFLTAQAWELSSHKKQGPGLLSRMGQTVRAVASSMRGVK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 NRPEEFMEMNNFIELFSQKINLIDKISQRIYKEEREYFDEMKEYGPIHILWSASEEDLVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NRPEEFMEMNNFIELFSQKINLIDKISQRIYKEEREYFDEMKEYGPIHILWSASEEDLVD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 TLKDVASCIDRCCKATEKRMSGLSEALLPVVHEYVLYSEMLMGVMKRRDQIQAELDSKVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TLKDVASCIDRCCKATEKRMSGLSEALLPVVHEYVLYSEMLMGVMKRRDQIQAELDSKVE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 VLTYKKADTDLLPEEIGKLEDKVECANNALKADWERWKQNMQNDIKLAFTDMAEENIHYY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 VLTYKKADTDLLPEEIGKLEDKVECANNALKADWERWKQNMQNDIKLAFTDMAEENIHYY 310 320 330 340 350 360 370 380 pF1KB6 EQCLATWESFLTSQTNLHLEEASEDKP ::::::::::::::::::::::::::: XP_016 EQCLATWESFLTSQTNLHLEEASEDKP 370 380 >>XP_006710741 (OMIM: 614904) PREDICTED: sorting nexin-7 (387 aa) initn: 2565 init1: 2565 opt: 2565 Z-score: 2624.1 bits: 494.3 E(85289): 2e-139 Smith-Waterman score: 2565; 100.0% identity (100.0% similar) in 387 aa overlap (1-387:1-387) 10 20 30 40 50 60 pF1KB6 MDMNSFSPMMPTSPLSMINQIKFEDEPDLKDLFITVDEPESHVTTIETFITYRIITKTSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MDMNSFSPMMPTSPLSMINQIKFEDEPDLKDLFITVDEPESHVTTIETFITYRIITKTSR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 GEFDSSEFEVRRRYQDFLWLKGKLEEAHPTLIIPPLPEKFIVKGMVERFNDDFIETRRKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 GEFDSSEFEVRRRYQDFLWLKGKLEEAHPTLIIPPLPEKFIVKGMVERFNDDFIETRRKA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 LHKFLNRIADHPTLTFNEDFKIFLTAQAWELSSHKKQGPGLLSRMGQTVRAVASSMRGVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LHKFLNRIADHPTLTFNEDFKIFLTAQAWELSSHKKQGPGLLSRMGQTVRAVASSMRGVK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 NRPEEFMEMNNFIELFSQKINLIDKISQRIYKEEREYFDEMKEYGPIHILWSASEEDLVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 NRPEEFMEMNNFIELFSQKINLIDKISQRIYKEEREYFDEMKEYGPIHILWSASEEDLVD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 TLKDVASCIDRCCKATEKRMSGLSEALLPVVHEYVLYSEMLMGVMKRRDQIQAELDSKVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 TLKDVASCIDRCCKATEKRMSGLSEALLPVVHEYVLYSEMLMGVMKRRDQIQAELDSKVE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 VLTYKKADTDLLPEEIGKLEDKVECANNALKADWERWKQNMQNDIKLAFTDMAEENIHYY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 VLTYKKADTDLLPEEIGKLEDKVECANNALKADWERWKQNMQNDIKLAFTDMAEENIHYY 310 320 330 340 350 360 370 380 pF1KB6 EQCLATWESFLTSQTNLHLEEASEDKP ::::::::::::::::::::::::::: XP_006 EQCLATWESFLTSQTNLHLEEASEDKP 370 380 >>NP_057060 (OMIM: 614904) sorting nexin-7 isoform a [Ho (451 aa) initn: 2565 init1: 2565 opt: 2565 Z-score: 2623.3 bits: 494.4 E(85289): 2.2e-139 Smith-Waterman score: 2565; 100.0% identity (100.0% similar) in 387 aa overlap (1-387:65-451) 10 20 30 pF1KB6 MDMNSFSPMMPTSPLSMINQIKFEDEPDLK :::::::::::::::::::::::::::::: NP_057 SGSSALLQAEVLDLDEDEDDLEVFSKDASLMDMNSFSPMMPTSPLSMINQIKFEDEPDLK 40 50 60 70 80 90 40 50 60 70 80 90 pF1KB6 DLFITVDEPESHVTTIETFITYRIITKTSRGEFDSSEFEVRRRYQDFLWLKGKLEEAHPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 DLFITVDEPESHVTTIETFITYRIITKTSRGEFDSSEFEVRRRYQDFLWLKGKLEEAHPT 100 110 120 130 140 150 100 110 120 130 140 150 pF1KB6 LIIPPLPEKFIVKGMVERFNDDFIETRRKALHKFLNRIADHPTLTFNEDFKIFLTAQAWE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 LIIPPLPEKFIVKGMVERFNDDFIETRRKALHKFLNRIADHPTLTFNEDFKIFLTAQAWE 160 170 180 190 200 210 160 170 180 190 200 210 pF1KB6 LSSHKKQGPGLLSRMGQTVRAVASSMRGVKNRPEEFMEMNNFIELFSQKINLIDKISQRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 LSSHKKQGPGLLSRMGQTVRAVASSMRGVKNRPEEFMEMNNFIELFSQKINLIDKISQRI 220 230 240 250 260 270 220 230 240 250 260 270 pF1KB6 YKEEREYFDEMKEYGPIHILWSASEEDLVDTLKDVASCIDRCCKATEKRMSGLSEALLPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 YKEEREYFDEMKEYGPIHILWSASEEDLVDTLKDVASCIDRCCKATEKRMSGLSEALLPV 280 290 300 310 320 330 280 290 300 310 320 330 pF1KB6 VHEYVLYSEMLMGVMKRRDQIQAELDSKVEVLTYKKADTDLLPEEIGKLEDKVECANNAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 VHEYVLYSEMLMGVMKRRDQIQAELDSKVEVLTYKKADTDLLPEEIGKLEDKVECANNAL 340 350 360 370 380 390 340 350 360 370 380 pF1KB6 KADWERWKQNMQNDIKLAFTDMAEENIHYYEQCLATWESFLTSQTNLHLEEASEDKP ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_057 KADWERWKQNMQNDIKLAFTDMAEENIHYYEQCLATWESFLTSQTNLHLEEASEDKP 400 410 420 430 440 450 >>XP_016856917 (OMIM: 614904) PREDICTED: sorting nexin-7 (336 aa) initn: 2199 init1: 2045 opt: 2045 Z-score: 2095.0 bits: 396.2 E(85289): 5.9e-110 Smith-Waterman score: 2101; 86.8% identity (86.8% similar) in 387 aa overlap (1-387:1-336) 10 20 30 40 50 60 pF1KB6 MDMNSFSPMMPTSPLSMINQIKFEDEPDLKDLFITVDEPESHVTTIETFITYRIITKTSR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MDMNSFSPMMPTSPLSMINQIKFEDEPDLKDLFITVDEPESHVTTIETFITYRIITKTSR 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 GEFDSSEFEVRRRYQDFLWLKGKLEEAHPTLIIPPLPEKFIVKGMVERFNDDFIETRRKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GEFDSSEFEVRRRYQDFLWLKGKLEEAHPTLIIPPLPEKFIVKGMVERFNDDFIETRRKA 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 LHKFLNRIADHPTLTFNEDFKIFLTAQAWELSSHKKQGPGLLSRMGQTVRAVASSMRGVK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LHKFLNRIADHPTLTFNEDFKIFLTAQAWELSSHKKQGPGLLSRMGQTVRAVASSMRGVK 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 NRPEEFMEMNNFIELFSQKINLIDKISQRIYKEEREYFDEMKEYGPIHILWSASEEDLVD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 NRPEEFMEMNNFIELFSQKINLIDKISQRIYKEEREYFDEMKEYGPIHILWSASEEDLVD 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 TLKDVASCIDRCCKATEKRMSGLSEALLPVVHEYVLYSEMLMGVMKRRDQIQAELDSKVE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TLKDVASCIDRCCKATEKRMSGLSEALLPVVHEYVLYSEMLMGVMKRRDQIQAELDSKVE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 VLTYKKADTDLLPEEIGKLEDKVECANNALKADWERWKQNMQNDIKLAFTDMAEENIHYY ::::::::::: XP_016 VLTYKKADTDL------------------------------------------------- 310 370 380 pF1KB6 EQCLATWESFLTSQTNLHLEEASEDKP ::::::::::::::::::::::::: XP_016 --CLATWESFLTSQTNLHLEEASEDKP 320 330 >>XP_006710740 (OMIM: 614904) PREDICTED: sorting nexin-7 (422 aa) initn: 2199 init1: 2045 opt: 2045 Z-score: 2093.8 bits: 396.3 E(85289): 7e-110 Smith-Waterman score: 2101; 86.8% identity (86.8% similar) in 387 aa overlap (1-387:87-422) 10 20 30 pF1KB6 MDMNSFSPMMPTSPLSMINQIKFEDEPDLK :::::::::::::::::::::::::::::: XP_006 SGSSALLQAEVLDLDEDEDDLEVFSKDASLMDMNSFSPMMPTSPLSMINQIKFEDEPDLK 60 70 80 90 100 110 40 50 60 70 80 90 pF1KB6 DLFITVDEPESHVTTIETFITYRIITKTSRGEFDSSEFEVRRRYQDFLWLKGKLEEAHPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DLFITVDEPESHVTTIETFITYRIITKTSRGEFDSSEFEVRRRYQDFLWLKGKLEEAHPT 120 130 140 150 160 170 100 110 120 130 140 150 pF1KB6 LIIPPLPEKFIVKGMVERFNDDFIETRRKALHKFLNRIADHPTLTFNEDFKIFLTAQAWE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LIIPPLPEKFIVKGMVERFNDDFIETRRKALHKFLNRIADHPTLTFNEDFKIFLTAQAWE 180 190 200 210 220 230 160 170 180 190 200 210 pF1KB6 LSSHKKQGPGLLSRMGQTVRAVASSMRGVKNRPEEFMEMNNFIELFSQKINLIDKISQRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 LSSHKKQGPGLLSRMGQTVRAVASSMRGVKNRPEEFMEMNNFIELFSQKINLIDKISQRI 240 250 260 270 280 290 220 230 240 250 260 270 pF1KB6 YKEEREYFDEMKEYGPIHILWSASEEDLVDTLKDVASCIDRCCKATEKRMSGLSEALLPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YKEEREYFDEMKEYGPIHILWSASEEDLVDTLKDVASCIDRCCKATEKRMSGLSEALLPV 300 310 320 330 340 350 280 290 300 310 320 330 pF1KB6 VHEYVLYSEMLMGVMKRRDQIQAELDSKVEVLTYKKADTDLLPEEIGKLEDKVECANNAL ::::::::::::::::::::::::::::::::::::::::: XP_006 VHEYVLYSEMLMGVMKRRDQIQAELDSKVEVLTYKKADTDL------------------- 360 370 380 390 340 350 360 370 380 pF1KB6 KADWERWKQNMQNDIKLAFTDMAEENIHYYEQCLATWESFLTSQTNLHLEEASEDKP ::::::::::::::::::::::::: XP_006 --------------------------------CLATWESFLTSQTNLHLEEASEDKP 400 410 420 >>NP_689424 (OMIM: 614904) sorting nexin-7 isoform b [Ho (396 aa) initn: 1570 init1: 1570 opt: 1570 Z-score: 1610.1 bits: 306.7 E(85289): 6.1e-83 Smith-Waterman score: 2072; 85.8% identity (85.8% similar) in 387 aa overlap (1-387:65-396) 10 20 30 pF1KB6 MDMNSFSPMMPTSPLSMINQIKFEDEPDLK :::::::::::::::::::::::::::::: NP_689 SGSSALLQAEVLDLDEDEDDLEVFSKDASLMDMNSFSPMMPTSPLSMINQIKFEDEPDLK 40 50 60 70 80 90 40 50 60 70 80 90 pF1KB6 DLFITVDEPESHVTTIETFITYRIITKTSRGEFDSSEFEVRRRYQDFLWLKGKLEEAHPT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 DLFITVDEPESHVTTIETFITYRIITKTSRGEFDSSEFEVRRRYQDFLWLKGKLEEAHPT 100 110 120 130 140 150 100 110 120 130 140 150 pF1KB6 LIIPPLPEKFIVKGMVERFNDDFIETRRKALHKFLNRIADHPTLTFNEDFKIFLTAQAWE :::: : NP_689 LIIP-------------------------------------------------------E 160 170 180 190 200 210 pF1KB6 LSSHKKQGPGLLSRMGQTVRAVASSMRGVKNRPEEFMEMNNFIELFSQKINLIDKISQRI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 LSSHKKQGPGLLSRMGQTVRAVASSMRGVKNRPEEFMEMNNFIELFSQKINLIDKISQRI 160 170 180 190 200 210 220 230 240 250 260 270 pF1KB6 YKEEREYFDEMKEYGPIHILWSASEEDLVDTLKDVASCIDRCCKATEKRMSGLSEALLPV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 YKEEREYFDEMKEYGPIHILWSASEEDLVDTLKDVASCIDRCCKATEKRMSGLSEALLPV 220 230 240 250 260 270 280 290 300 310 320 330 pF1KB6 VHEYVLYSEMLMGVMKRRDQIQAELDSKVEVLTYKKADTDLLPEEIGKLEDKVECANNAL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 VHEYVLYSEMLMGVMKRRDQIQAELDSKVEVLTYKKADTDLLPEEIGKLEDKVECANNAL 280 290 300 310 320 330 340 350 360 370 380 pF1KB6 KADWERWKQNMQNDIKLAFTDMAEENIHYYEQCLATWESFLTSQTNLHLEEASEDKP ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_689 KADWERWKQNMQNDIKLAFTDMAEENIHYYEQCLATWESFLTSQTNLHLEEASEDKP 340 350 360 370 380 390 >>NP_003785 (OMIM: 605931) sorting nexin-4 [Homo sapiens (450 aa) initn: 279 init1: 113 opt: 330 Z-score: 345.7 bits: 73.0 E(85289): 1.6e-12 Smith-Waterman score: 339; 25.7% identity (60.5% similar) in 296 aa overlap (29-312:55-345) 10 20 30 40 50 pF1KB6 MDMNSFSPMMPTSPLSMINQIKFEDEPDLKDLFITVDEPESH-----VTTIETFITYR :: . :.:.: :.. .. ::. .: NP_003 AGLGAAVGKEAEGAGEESSGVDTMTHNNFWLKKIEISVSEAEKRTGRNAMNMQETYTAYL 30 40 50 60 70 80 60 70 80 90 100 pF1KB6 IITKTSRGEFDSSEFE--VRRRYQDFLWLKGKLEEAHPTLIIPPLPEK---FIVKGM-VE : :.. . .: . . :::..: :.. : .: ...:::::: :. . . .. NP_003 IETRSVEHTDGQSVLTDSLWRRYSEFELLRSYLLVYYPHIVVPPLPEKRAEFVWHKLSAD 90 100 110 120 130 140 110 120 130 140 150 160 pF1KB6 RFNDDFIETRRKALHKFLNRIADHPTLTFNEDFKIFLTAQA-WELSSHKKQGPGLLSRMG .. ::.: :: .:..:: :::.:: : .. : .::: .. :. . .. :. . NP_003 NMDPDFVERRRIGLENFLLRIASHPILCRDKIFYLFLTQEGNWKETVNET---GFQLKAD 150 160 170 180 190 200 170 180 190 200 210 220 pF1KB6 QTVRAVASSMRGVKNRPEEFMEMNNFIELFSQKINLIDKISQRIYKEEREYFDEMKEYGP . ..:. ...: ::: ..: ..... . ... :. . .. :. . . .:: NP_003 SRLKALNATFR-VKNPDKRFTDLKHYSDELQSVISHLLRVRARVADRLYGVYKVHGNYGR 210 220 230 240 250 260 230 240 250 260 270 280 pF1KB6 IHILWSASEEDLVDTLKDVASCIDRCCKATEKRMSGLSEALLPVVHEYVLYSEMLMGVMK . ::: :... : :.... .: .. . . : ..::..:.: : .: . NP_003 VFSEWSAIEKEMGDGLQSAGHHMDVYASSIDDILED-EEHYADQLKEYLFYAEALRAVCR 270 280 290 300 310 290 300 310 320 330 340 pF1KB6 RRDQIQAELDSKVEVLTYKKADTDLLPEEIGKLEDKVECANNALKADWERWKQNMQNDIK ... .: .:. .. :. :: . . : NP_003 KHELMQYDLEMAAQDLASKKQQCEELVTGTVRTFSLKGMTTKLFGQETPEQREARIKVLE 320 330 340 350 360 370 387 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 04:20:03 2016 done: Sat Nov 5 04:20:05 2016 Total Scan time: 8.380 Total Display time: 0.060 Function used was FASTA [36.3.4 Apr, 2011]