FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6523, 364 aa 1>>>pF1KB6523 364 - 364 aa - 364 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.1304+/-0.000762; mu= 10.4591+/- 0.046 mean_var=181.3877+/-37.193, 0's: 0 Z-trim(115.1): 83 B-trim: 0 in 0/54 Lambda= 0.095229 statistics sampled from 15611 (15702) to 15611 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.791), E-opt: 0.2 (0.482), width: 16 Scan time: 3.230 The best scores are: opt bits E(32554) CCDS8936.1 STAC3 gene_id:246329|Hs108|chr12 ( 364) 2515 357.2 1.3e-98 CCDS66406.1 STAC3 gene_id:246329|Hs108|chr12 ( 325) 2269 323.4 1.8e-88 CCDS66405.1 STAC3 gene_id:246329|Hs108|chr12 ( 178) 1214 178.1 5e-45 CCDS11335.1 STAC2 gene_id:342667|Hs108|chr17 ( 411) 467 75.9 6.9e-14 CCDS77722.1 STAC gene_id:6769|Hs108|chr3 ( 341) 431 70.9 1.9e-12 CCDS2662.1 STAC gene_id:6769|Hs108|chr3 ( 402) 431 70.9 2.1e-12 >>CCDS8936.1 STAC3 gene_id:246329|Hs108|chr12 (364 aa) initn: 2515 init1: 2515 opt: 2515 Z-score: 1884.1 bits: 357.2 E(32554): 1.3e-98 Smith-Waterman score: 2515; 100.0% identity (100.0% similar) in 364 aa overlap (1-364:1-364) 10 20 30 40 50 60 pF1KB6 MTEKEVLESPKPSFPAETRQSGLQRLKQLLRKGSTGTKEMELPPEPQANGEAVGAGGGPI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS89 MTEKEVLESPKPSFPAETRQSGLQRLKQLLRKGSTGTKEMELPPEPQANGEAVGAGGGPI 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 YYIYEEEEEEEEEEEEPPPEPPKLVNDKPHKFKDHFFKKPKFCDVCARMIVLNNKFGLRC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS89 YYIYEEEEEEEEEEEEPPPEPPKLVNDKPHKFKDHFFKKPKFCDVCARMIVLNNKFGLRC 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 KNCKTNIHEHCQSYVEMQRCFGKIPPGFHRAYSSPLYSNQQYACVKDLSAANRNDPVFET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS89 KNCKTNIHEHCQSYVEMQRCFGKIPPGFHRAYSSPLYSNQQYACVKDLSAANRNDPVFET 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 LRTGVIMANKERKKGQADKKNPVAAMMEEEPESARPEEGKPQDGNPEGDKKAEKKTPDDK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS89 LRTGVIMANKERKKGQADKKNPVAAMMEEEPESARPEEGKPQDGNPEGDKKAEKKTPDDK 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 HKQPGFQQSHYFVALYRFKALEKDDLDFPPGEKITVIDDSNEEWWRGKIGEKVGFFPPNF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS89 HKQPGFQQSHYFVALYRFKALEKDDLDFPPGEKITVIDDSNEEWWRGKIGEKVGFFPPNF 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 IIRVRAGERVHRVTRSFVGNREIGQITLKKDQIVVQKGDEAGGYVKVYTGRKVGLFPTDF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS89 IIRVRAGERVHRVTRSFVGNREIGQITLKKDQIVVQKGDEAGGYVKVYTGRKVGLFPTDF 310 320 330 340 350 360 pF1KB6 LEEI :::: CCDS89 LEEI >>CCDS66406.1 STAC3 gene_id:246329|Hs108|chr12 (325 aa) initn: 2269 init1: 2269 opt: 2269 Z-score: 1702.0 bits: 323.4 E(32554): 1.8e-88 Smith-Waterman score: 2269; 100.0% identity (100.0% similar) in 325 aa overlap (40-364:1-325) 10 20 30 40 50 60 pF1KB6 PKPSFPAETRQSGLQRLKQLLRKGSTGTKEMELPPEPQANGEAVGAGGGPIYYIYEEEEE :::::::::::::::::::::::::::::: CCDS66 MELPPEPQANGEAVGAGGGPIYYIYEEEEE 10 20 30 70 80 90 100 110 120 pF1KB6 EEEEEEEPPPEPPKLVNDKPHKFKDHFFKKPKFCDVCARMIVLNNKFGLRCKNCKTNIHE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 EEEEEEEPPPEPPKLVNDKPHKFKDHFFKKPKFCDVCARMIVLNNKFGLRCKNCKTNIHE 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB6 HCQSYVEMQRCFGKIPPGFHRAYSSPLYSNQQYACVKDLSAANRNDPVFETLRTGVIMAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 HCQSYVEMQRCFGKIPPGFHRAYSSPLYSNQQYACVKDLSAANRNDPVFETLRTGVIMAN 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB6 KERKKGQADKKNPVAAMMEEEPESARPEEGKPQDGNPEGDKKAEKKTPDDKHKQPGFQQS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 KERKKGQADKKNPVAAMMEEEPESARPEEGKPQDGNPEGDKKAEKKTPDDKHKQPGFQQS 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB6 HYFVALYRFKALEKDDLDFPPGEKITVIDDSNEEWWRGKIGEKVGFFPPNFIIRVRAGER :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 HYFVALYRFKALEKDDLDFPPGEKITVIDDSNEEWWRGKIGEKVGFFPPNFIIRVRAGER 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB6 VHRVTRSFVGNREIGQITLKKDQIVVQKGDEAGGYVKVYTGRKVGLFPTDFLEEI ::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 VHRVTRSFVGNREIGQITLKKDQIVVQKGDEAGGYVKVYTGRKVGLFPTDFLEEI 280 290 300 310 320 >>CCDS66405.1 STAC3 gene_id:246329|Hs108|chr12 (178 aa) initn: 1214 init1: 1214 opt: 1214 Z-score: 921.9 bits: 178.1 E(32554): 5e-45 Smith-Waterman score: 1214; 100.0% identity (100.0% similar) in 178 aa overlap (187-364:1-178) 160 170 180 190 200 210 pF1KB6 YSNQQYACVKDLSAANRNDPVFETLRTGVIMANKERKKGQADKKNPVAAMMEEEPESARP :::::::::::::::::::::::::::::: CCDS66 MANKERKKGQADKKNPVAAMMEEEPESARP 10 20 30 220 230 240 250 260 270 pF1KB6 EEGKPQDGNPEGDKKAEKKTPDDKHKQPGFQQSHYFVALYRFKALEKDDLDFPPGEKITV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 EEGKPQDGNPEGDKKAEKKTPDDKHKQPGFQQSHYFVALYRFKALEKDDLDFPPGEKITV 40 50 60 70 80 90 280 290 300 310 320 330 pF1KB6 IDDSNEEWWRGKIGEKVGFFPPNFIIRVRAGERVHRVTRSFVGNREIGQITLKKDQIVVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS66 IDDSNEEWWRGKIGEKVGFFPPNFIIRVRAGERVHRVTRSFVGNREIGQITLKKDQIVVQ 100 110 120 130 140 150 340 350 360 pF1KB6 KGDEAGGYVKVYTGRKVGLFPTDFLEEI :::::::::::::::::::::::::::: CCDS66 KGDEAGGYVKVYTGRKVGLFPTDFLEEI 160 170 >>CCDS11335.1 STAC2 gene_id:342667|Hs108|chr17 (411 aa) initn: 734 init1: 340 opt: 467 Z-score: 362.8 bits: 75.9 E(32554): 6.9e-14 Smith-Waterman score: 732; 38.8% identity (64.4% similar) in 317 aa overlap (77-364:95-411) 50 60 70 80 90 100 pF1KB6 QANGEAVGAGGGPIYYIYEEEEEEEEEEEEPPPEPPKLVNDKP---HKFKDHFFKKPKFC : : : :. :: :.:..: ::. . : CCDS11 EVLLTPPTPLPPPSPPPTASDRGLATPSPSPCPVPRPLAALKPVRLHSFQEHVFKRASPC 70 80 90 100 110 120 110 120 130 140 150 160 pF1KB6 DVCARMIVLNNKFGLRCKNCKTNIHEHCQSYVEMQRCFGKIPPGFHRAYSSPLYSNQQY- ..: ..:: :.: ::::: ::...: :. . :.: :: .:.: .:::: .. CCDS11 ELCHQLIVGNSKQGLRCKMCKVSVHLWCSEEISHQQCPGKTSTSFRRNFSSPLLVHEPPP 130 140 150 160 170 180 170 180 190 200 210 pF1KB6 ACVKDLSA-----ANRNDPVFETLRTGVIMANKERKKGQADKKNPVAAMME-----EEPE .:. . . ... :::.:::: :. .: .:.. .. ...:. .. : :. : CCDS11 VCATSKESPPTGDSGKVDPVYETLRYGTSLALMNRSSFSSTSESPTRSLSERDELTEDGE 190 200 210 220 230 240 220 230 240 250 pF1KB6 -SARP-EEGKPQDGNPEGDKKAEKKTPDDKHKQPGFQQS-----------HYFVALYRFK : : ::: ....: ::.. : ..:.:: : . .::::.: CCDS11 GSIRSSEEGPGDSASPVFTAPAESEGPGPEEKSPGQQLPKATLRKDVGPMYSYVALYKFL 250 260 270 280 290 300 260 270 280 290 300 310 pF1KB6 ALEKDDLDFPPGEKITVIDDSNEEWWRGKIGEKVGFFPPNFIIRVRAGERVHRVTRSFVG :..:: . ::..: ..:::::.::.::::..::::: ::. ::: :: : : . : : CCDS11 PQENNDLALQPGDRIMLVDDSNEDWWKGKIGDRVGFFPANFVQRVRPGENVWRCCQPFSG 310 320 330 340 350 360 320 330 340 350 360 pF1KB6 NREIGQITLKKDQIVVQKG--DEAGGYVKVYTGRKVGLFPTDFLEEI :.: : ..::..:: : : .: :...: .:.: :: :.: : :: CCDS11 NKEQGYMSLKENQICVGVGRSKDADGFIRVSSGKKRGLVPVDALTEI 370 380 390 400 410 >>CCDS77722.1 STAC gene_id:6769|Hs108|chr3 (341 aa) initn: 581 init1: 417 opt: 431 Z-score: 337.1 bits: 70.9 E(32554): 1.9e-12 Smith-Waterman score: 490; 28.9% identity (52.8% similar) in 388 aa overlap (4-364:17-341) 10 20 30 40 pF1KB6 MTEKEVLESPKPSFPAETRQSGLQRLKQLLRKGSTGTKEMELPPEPQ ::.. . .: :: : .: ..:..: :. : :: .. . CCDS77 MIPPSSPREDGVDGLPKEAVGAEQPPSPAST-SSQESKLQKLKRSLSFKTKSLR----SK 10 20 30 40 50 50 60 70 80 90 pF1KB6 ANGEAVGAGGGPIYYIYEEEEEEEEEEEEPPPEPPKLVND----------KPHKFKDHFF . . .. . . . : : : : .:.. : : :....: CCDS77 SADNFFQRTNSEDMKLQAHMVAEISPSSSPLPAPGSLTSTPARAGLHPGGKAHAFQEYIF 60 70 80 90 100 110 100 110 120 130 140 150 pF1KB6 KKPKFCDVCARMIVLNNKFGLRCKNCKTNIHEHCQSYVEMQRCFGKIPPGFHRAYSSPLY ::: ::::: .::: CCDS77 KKPTFCDVCNHMIV---------------------------------------------- 120 160 170 180 190 200 210 pF1KB6 SNQQYACVKDLSAANRNDPVFETLRTGVIMANKERK----KGQADKKNPVAAMMEEEPES :: .:. :::.:::: :. .:.. .: .:. . . .. . : :: CCDS77 -----AC------GNKVDPVYETLRFGTSLAQRTKKGSSGSGSDSPHRTSTSDLVEVPEE 130 140 150 160 170 220 230 240 250 260 pF1KB6 ARPEEGK-------------PQDGNPEGDKKAEKKTPDDKHKQPGFQQSHYFVALYRFKA : : :..:. . :.. . . . .. .:.. : ::::.: CCDS77 ANGPGGGYDLRKRSNSVFTYPENGTDDFRDPAKNINHQGSLSKDPLQMNTY-VALYKFVP 180 190 200 210 220 230 270 280 290 300 310 320 pF1KB6 LEKDDLDFPPGEKITVIDDSNEEWWRGKIGEKVGFFPPNFIIRVRAGERVHRVTRSFVGN :..::.. ::. ::...::::.::.::: ...:::: ::. :.. .:.. : .:.:.: CCDS77 QENEDLEMRPGDIITLLEDSNEDWWKGKIQDRIGFFPANFVQRLQQNEKIFRCVRTFIGC 240 250 260 270 280 290 330 340 350 360 pF1KB6 REIGQITLKKDQIVVQKGDEAGGYVKVYTGRKVGLFPTDFLEEI .: ::::::..:: :.. .: :...: .:.: ::.: : ::.: CCDS77 KEQGQITLKENQICVSSEEEQDGFIRVLSGKKKGLIPLDVLENI 300 310 320 330 340 >>CCDS2662.1 STAC gene_id:6769|Hs108|chr3 (402 aa) initn: 773 init1: 417 opt: 431 Z-score: 336.2 bits: 70.9 E(32554): 2.1e-12 Smith-Waterman score: 809; 35.5% identity (63.3% similar) in 392 aa overlap (4-364:17-402) 10 20 30 40 pF1KB6 MTEKEVLESPKPSFPAETRQSGLQRLKQLLRKGSTGTKEMELPPEPQ ::.. . .: :: : .: ..:..: :. : :: .. . CCDS26 MIPPSSPREDGVDGLPKEAVGAEQPPSPAST-SSQESKLQKLKRSLSFKTKSLR----SK 10 20 30 40 50 50 60 70 80 90 pF1KB6 ANGEAVGAGGGPIYYIYEEEEEEEEEEEEPPPEPPKLVND----------KPHKFKDHFF . . .. . . . : : : : .:.. : : :....: CCDS26 SADNFFQRTNSEDMKLQAHMVAEISPSSSPLPAPGSLTSTPARAGLHPGGKAHAFQEYIF 60 70 80 90 100 110 100 110 120 130 140 150 pF1KB6 KKPKFCDVCARMIV-LNNKFGLRCKNCKTNIHEHCQSYVEMQRCFGKIPPGFHRAYSSPL ::: ::::: .::: : : ::::: :: .::..: . . :::.::.: ::.: ::::: CCDS26 KKPTFCDVCNHMIVGTNAKHGLRCKACKMSIHHKCTDGLAPQRCMGKLPKGFRRYYSSPL 120 130 140 150 160 170 160 170 180 190 200 pF1KB6 YSNQQYACVKD---LSAANRNDPVFETLRTGVIMANKERK----KGQADKKNPVAAMMEE ..:..:.:. .. .:. :::.:::: :. .:.. .: .:. . . .. . : CCDS26 LIHEQFGCIKEVMPIACGNKVDPVYETLRFGTSLAQRTKKGSSGSGSDSPHRTSTSDLVE 180 190 200 210 220 230 210 220 230 240 250 pF1KB6 EPESARPEEGK-------------PQDGNPEGDKKAEKKTPDDKHKQPGFQQSHYFVALY :: : : :..:. . :.. . . . .. .:.. : :::: CCDS26 VPEEANGPGGGYDLRKRSNSVFTYPENGTDDFRDPAKNINHQGSLSKDPLQMNTY-VALY 240 250 260 270 280 290 260 270 280 290 300 310 pF1KB6 RFKALEKDDLDFPPGEKITVIDDSNEEWWRGKIGEKVGFFPPNFIIRVRAGERVHRVTRS .: :..::.. ::. ::...::::.::.::: ...:::: ::. :.. .:.. : .:. CCDS26 KFVPQENEDLEMRPGDIITLLEDSNEDWWKGKIQDRIGFFPANFVQRLQQNEKIFRCVRT 300 310 320 330 340 350 320 330 340 350 360 pF1KB6 FVGNREIGQITLKKDQIVVQKGDEAGGYVKVYTGRKVGLFPTDFLEEI :.: .: ::::::..:: :.. .: :...: .:.: ::.: : ::.: CCDS26 FIGCKEQGQITLKENQICVSSEEEQDGFIRVLSGKKKGLIPLDVLENI 360 370 380 390 400 364 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 16:53:54 2016 done: Sat Nov 5 16:53:55 2016 Total Scan time: 3.230 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]