FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6527, 365 aa 1>>>pF1KB6527 365 - 365 aa - 365 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.4484+/-0.000431; mu= 12.6880+/- 0.026 mean_var=197.1482+/-44.263, 0's: 0 Z-trim(117.7): 367 B-trim: 1560 in 1/49 Lambda= 0.091344 statistics sampled from 29527 (29933) to 29527 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.712), E-opt: 0.2 (0.351), width: 16 Scan time: 7.020 The best scores are: opt bits E(85289) NP_060450 (OMIM: 607908,616827) LIM and senescent ( 365) 2676 365.3 1.2e-100 NP_001154875 (OMIM: 607908,616827) LIM and senesce ( 341) 2489 340.6 3e-93 NP_001129509 (OMIM: 607908,616827) LIM and senesce ( 363) 2488 340.5 3.4e-93 NP_001154876 (OMIM: 607908,616827) LIM and senesce ( 336) 2481 339.6 6.2e-93 NP_001180413 (OMIM: 602567) LIM and senescent cell ( 362) 2204 303.1 6.4e-82 NP_001180411 (OMIM: 602567) LIM and senescent cell ( 329) 2161 297.4 3.1e-80 NP_001180412 (OMIM: 602567) LIM and senescent cell ( 337) 2159 297.1 3.7e-80 NP_001180414 (OMIM: 602567) LIM and senescent cell ( 387) 2159 297.2 4e-80 NP_004978 (OMIM: 602567) LIM and senescent cell an ( 325) 2152 296.2 6.9e-80 NP_001180417 (OMIM: 602567) LIM and senescent cell ( 325) 2152 296.2 6.9e-80 XP_005264005 (OMIM: 602567) PREDICTED: LIM and sen ( 373) 2135 294.0 3.5e-79 XP_005264006 (OMIM: 602567) PREDICTED: LIM and sen ( 348) 2090 288.1 2.1e-77 XP_005264003 (OMIM: 602567) PREDICTED: LIM and sen ( 398) 2090 288.2 2.2e-77 XP_005264008 (OMIM: 602567) PREDICTED: LIM and sen ( 336) 2083 287.1 3.8e-77 XP_005264007 (OMIM: 602567) PREDICTED: LIM and sen ( 336) 2083 287.1 3.8e-77 XP_005263767 (OMIM: 607908,616827) PREDICTED: LIM ( 272) 2004 276.6 4.6e-74 XP_016859581 (OMIM: 602567) PREDICTED: LIM and sen ( 317) 1788 248.2 1.9e-65 XP_016859583 (OMIM: 602567) PREDICTED: LIM and sen ( 317) 1788 248.2 1.9e-65 XP_016859580 (OMIM: 602567) PREDICTED: LIM and sen ( 317) 1788 248.2 1.9e-65 XP_016859582 (OMIM: 602567) PREDICTED: LIM and sen ( 317) 1788 248.2 1.9e-65 XP_006712690 (OMIM: 607908,616827) PREDICTED: LIM ( 225) 1632 227.5 2.4e-59 XP_011509755 (OMIM: 607908,616827) PREDICTED: LIM ( 324) 1455 204.4 3.1e-52 NP_001243471 (OMIM: 607908,616827) LIM and senesce ( 189) 1371 193.0 4.8e-49 XP_006712691 (OMIM: 607908,616827) PREDICTED: LIM ( 190) 1052 150.9 2.2e-36 XP_016859958 (OMIM: 607908,616827) PREDICTED: LIM ( 238) 628 95.2 1.6e-19 NP_001243354 (OMIM: 605904) PDZ and LIM domain pro ( 271) 470 74.4 3.3e-13 XP_011533001 (OMIM: 605903) PREDICTED: PDZ and LIM ( 309) 468 74.3 4.3e-13 NP_001243357 (OMIM: 605904) PDZ and LIM domain pro ( 474) 470 74.8 4.6e-13 NP_001011513 (OMIM: 605904) PDZ and LIM domain pro ( 487) 470 74.8 4.6e-13 XP_005262755 (OMIM: 605904) PREDICTED: PDZ and LIM ( 493) 470 74.8 4.7e-13 XP_011533000 (OMIM: 605903) PREDICTED: PDZ and LIM ( 364) 468 74.4 4.7e-13 XP_016863147 (OMIM: 605904) PREDICTED: PDZ and LIM ( 498) 470 74.8 4.7e-13 NP_976227 (OMIM: 605903) PDZ and LIM domain protei ( 423) 468 74.4 5.1e-13 NP_006448 (OMIM: 605904) PDZ and LIM domain protei ( 596) 470 74.9 5.2e-13 XP_011529845 (OMIM: 605904) PREDICTED: PDZ and LIM ( 600) 470 74.9 5.3e-13 XP_016863146 (OMIM: 605904) PREDICTED: PDZ and LIM ( 602) 470 74.9 5.3e-13 XP_006714133 (OMIM: 605904) PREDICTED: PDZ and LIM ( 605) 470 74.9 5.3e-13 XP_006714132 (OMIM: 605904) PREDICTED: PDZ and LIM ( 607) 470 74.9 5.3e-13 XP_005262753 (OMIM: 605904) PREDICTED: PDZ and LIM ( 619) 470 74.9 5.3e-13 NP_005442 (OMIM: 605903) PDZ and LIM domain protei ( 457) 468 74.5 5.4e-13 NP_001243355 (OMIM: 605904) PDZ and LIM domain pro ( 625) 470 74.9 5.4e-13 XP_006714131 (OMIM: 605904) PREDICTED: PDZ and LIM ( 630) 470 74.9 5.4e-13 XP_005262752 (OMIM: 605904) PREDICTED: PDZ and LIM ( 728) 470 75.0 5.9e-13 XP_005262750 (OMIM: 605904) PREDICTED: PDZ and LIM ( 734) 470 75.0 5.9e-13 XP_006714129 (OMIM: 605904) PREDICTED: PDZ and LIM ( 739) 470 75.0 5.9e-13 NP_001243356 (OMIM: 605904) PDZ and LIM domain pro ( 483) 448 71.9 3.4e-12 NP_001309395 (OMIM: 605126) four and a half LIM do ( 284) 418 67.6 3.9e-11 NP_001164278 (OMIM: 605126) four and a half LIM do ( 284) 418 67.6 3.9e-11 NP_065228 (OMIM: 605126) four and a half LIM domai ( 284) 418 67.6 3.9e-11 NP_001309396 (OMIM: 605126) four and a half LIM do ( 284) 418 67.6 3.9e-11 >>NP_060450 (OMIM: 607908,616827) LIM and senescent cell (365 aa) initn: 2676 init1: 2676 opt: 2676 Z-score: 1927.9 bits: 365.3 E(85289): 1.2e-100 Smith-Waterman score: 2676; 100.0% identity (100.0% similar) in 365 aa overlap (1-365:1-365) 10 20 30 40 50 60 pF1KB6 MAARLGALAASGLYRRRQHRQSPPPATGNMSDALANAVCQRCQARFSPAERIVNSNGELY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 MAARLGALAASGLYRRRQHRQSPPPATGNMSDALANAVCQRCQARFSPAERIVNSNGELY 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 HEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFIIGRVIKAMNNNWH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 HEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFIIGRVIKAMNNNWH 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 PGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVIDEQPLMFRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 PGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVIDEQPLMFRS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 DAYHPDHFNCTHCGKELTAEARELKGELYCLPCHDKMGVPICGACRRPIEGRVVNALGKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 DAYHPDHFNCTHCGKELTAEARELKGELYCLPCHDKMGVPICGACRRPIEGRVVNALGKQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 WHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDVVSALNKAW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 WHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDVVSALNKAW 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 CVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEKFPLELKKRLKKLSELTSRKAQPKAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 CVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEKFPLELKKRLKKLSELTSRKAQPKAT 310 320 330 340 350 360 pF1KB6 DLNSA ::::: NP_060 DLNSA >>NP_001154875 (OMIM: 607908,616827) LIM and senescent c (341 aa) initn: 2488 init1: 2488 opt: 2489 Z-score: 1795.0 bits: 340.6 E(85289): 3e-93 Smith-Waterman score: 2489; 99.7% identity (99.7% similar) in 340 aa overlap (27-365:2-341) 10 20 30 40 50 pF1KB6 MAARLGALAASGLYRRRQHRQSPPPATG-NMSDALANAVCQRCQARFSPAERIVNSNGEL :: ::::::::::::::::::::::::::::::: NP_001 MTGSNMSDALANAVCQRCQARFSPAERIVNSNGEL 10 20 30 60 70 80 90 100 110 pF1KB6 YHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFIIGRVIKAMNNNW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 YHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFIIGRVIKAMNNNW 40 50 60 70 80 90 120 130 140 150 160 170 pF1KB6 HPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVIDEQPLMFR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVIDEQPLMFR 100 110 120 130 140 150 180 190 200 210 220 230 pF1KB6 SDAYHPDHFNCTHCGKELTAEARELKGELYCLPCHDKMGVPICGACRRPIEGRVVNALGK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SDAYHPDHFNCTHCGKELTAEARELKGELYCLPCHDKMGVPICGACRRPIEGRVVNALGK 160 170 180 190 200 210 240 250 260 270 280 290 pF1KB6 QWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDVVSALNKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 QWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDVVSALNKA 220 230 240 250 260 270 300 310 320 330 340 350 pF1KB6 WCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEKFPLELKKRLKKLSELTSRKAQPKA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEKFPLELKKRLKKLSELTSRKAQPKA 280 290 300 310 320 330 360 pF1KB6 TDLNSA :::::: NP_001 TDLNSA 340 >>NP_001129509 (OMIM: 607908,616827) LIM and senescent c (363 aa) initn: 2488 init1: 2488 opt: 2488 Z-score: 1794.0 bits: 340.5 E(85289): 3.4e-93 Smith-Waterman score: 2488; 100.0% identity (100.0% similar) in 337 aa overlap (29-365:27-363) 10 20 30 40 50 60 pF1KB6 MAARLGALAASGLYRRRQHRQSPPPATGNMSDALANAVCQRCQARFSPAERIVNSNGELY :::::::::::::::::::::::::::::::: NP_001 MTGRKRKWGETGTGSGAAPAAALRWSNMSDALANAVCQRCQARFSPAERIVNSNGELY 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 HEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFIIGRVIKAMNNNWH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFIIGRVIKAMNNNWH 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 PGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVIDEQPLMFRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVIDEQPLMFRS 120 130 140 150 160 170 190 200 210 220 230 240 pF1KB6 DAYHPDHFNCTHCGKELTAEARELKGELYCLPCHDKMGVPICGACRRPIEGRVVNALGKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DAYHPDHFNCTHCGKELTAEARELKGELYCLPCHDKMGVPICGACRRPIEGRVVNALGKQ 180 190 200 210 220 230 250 260 270 280 290 300 pF1KB6 WHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDVVSALNKAW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDVVSALNKAW 240 250 260 270 280 290 310 320 330 340 350 360 pF1KB6 CVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEKFPLELKKRLKKLSELTSRKAQPKAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEKFPLELKKRLKKLSELTSRKAQPKAT 300 310 320 330 340 350 pF1KB6 DLNSA ::::: NP_001 DLNSA 360 >>NP_001154876 (OMIM: 607908,616827) LIM and senescent c (336 aa) initn: 2481 init1: 2481 opt: 2481 Z-score: 1789.4 bits: 339.6 E(85289): 6.2e-93 Smith-Waterman score: 2481; 100.0% identity (100.0% similar) in 336 aa overlap (30-365:1-336) 10 20 30 40 50 60 pF1KB6 MAARLGALAASGLYRRRQHRQSPPPATGNMSDALANAVCQRCQARFSPAERIVNSNGELY ::::::::::::::::::::::::::::::: NP_001 MSDALANAVCQRCQARFSPAERIVNSNGELY 10 20 30 70 80 90 100 110 120 pF1KB6 HEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFIIGRVIKAMNNNWH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFIIGRVIKAMNNNWH 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB6 PGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVIDEQPLMFRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVIDEQPLMFRS 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB6 DAYHPDHFNCTHCGKELTAEARELKGELYCLPCHDKMGVPICGACRRPIEGRVVNALGKQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 DAYHPDHFNCTHCGKELTAEARELKGELYCLPCHDKMGVPICGACRRPIEGRVVNALGKQ 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB6 WHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDVVSALNKAW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 WHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDVVSALNKAW 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB6 CVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEKFPLELKKRLKKLSELTSRKAQPKAT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEKFPLELKKRLKKLSELTSRKAQPKAT 280 290 300 310 320 330 pF1KB6 DLNSA ::::: NP_001 DLNSA >>NP_001180413 (OMIM: 602567) LIM and senescent cell ant (362 aa) initn: 2165 init1: 2165 opt: 2204 Z-score: 1591.8 bits: 303.1 E(85289): 6.4e-82 Smith-Waterman score: 2204; 80.8% identity (92.5% similar) in 360 aa overlap (2-354:3-362) 10 20 30 40 50 pF1KB6 MAARLGALAASGLYRRRQHRQS-------PPPATGNMSDALANAVCQRCQARFSPAERI : .: :. :::::::. : . : .::..:::.:.:.::.. :.:::.: NP_001 MTALQLKELSHSGLYRRRRDRPDSLRVNGLPEEELSNMANALASATCERCKGGFAPAEKI 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 VNSNGELYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFIIGRVI ::::::::::.::::::::. ::::::::::::::::::::::::::: .:::::::::: NP_001 VNSNGELYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFIIGRVI 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 KAMNNNWHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVID :::::.::: ::::.::. :::.::::::::::::::::::::.::::::::.:: .:: NP_001 KAMNNSWHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAIID 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB6 EQPLMFRSDAYHPDHFNCTHCGKELTAEARELKGELYCLPCHDKMGVPICGACRRPIEGR ::::.:..: ::::::::..:::::::.:::::::::::::::::::::::::::::::: NP_001 EQPLIFKNDPYHPDHFNCANCGKELTADARELKGELYCLPCHDKMGVPICGACRRPIEGR 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB6 VVNALGKQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDV ::::.:::::::::::::::::::::::::.::::::::::::::::::..:..:::::: NP_001 VVNAMGKQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLFGDVCFHCNRVIEGDV 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB6 VSALNKAWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEKFPLELKKRLKKLSELTS ::::::::::.::.:::::.::::::::::::::::::.::::::::::::::::.: . NP_001 VSALNKAWCVNCFACSTCNTKLTLKNKFVEFDMKPVCKKCYEKFPLELKKRLKKLAETLG 310 320 330 340 350 360 360 pF1KB6 RKAQPKATDLNSA :: NP_001 RK >>NP_001180411 (OMIM: 602567) LIM and senescent cell ant (329 aa) initn: 2161 init1: 2161 opt: 2161 Z-score: 1561.6 bits: 297.4 E(85289): 3.1e-80 Smith-Waterman score: 2161; 85.4% identity (96.6% similar) in 328 aa overlap (27-354:2-329) 10 20 30 40 50 60 pF1KB6 MAARLGALAASGLYRRRQHRQSPPPATGNMSDALANAVCQRCQARFSPAERIVNSNGELY : ::..:::.:.:.::.. :.:::.::::::::: NP_001 MTCNMANALASATCERCKGGFAPAEKIVNSNGELY 10 20 30 70 80 90 100 110 120 pF1KB6 HEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFIIGRVIKAMNNNWH ::.::::::::. ::::::::::::::::::::::::::: .:::::::::::::::.:: NP_001 HEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFIIGRVIKAMNNSWH 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB6 PGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVIDEQPLMFRS : ::::.::. :::.::::::::::::::::::::.::::::::.:: .::::::.:.. NP_001 PECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAIIDEQPLIFKN 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB6 DAYHPDHFNCTHCGKELTAEARELKGELYCLPCHDKMGVPICGACRRPIEGRVVNALGKQ : ::::::::..:::::::.::::::::::::::::::::::::::::::::::::.::: NP_001 DPYHPDHFNCANCGKELTADARELKGELYCLPCHDKMGVPICGACRRPIEGRVVNAMGKQ 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB6 WHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDVVSALNKAW ::::::::::::::::::::::.::::::::::::::::::..:..:::::::::::::: NP_001 WHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLFGDVCFHCNRVIEGDVVSALNKAW 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB6 CVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEKFPLELKKRLKKLSELTSRKAQPKAT ::.::.:::::.::::::::::::::::::.::::::::::::::::.: .:: NP_001 CVNCFACSTCNTKLTLKNKFVEFDMKPVCKKCYEKFPLELKKRLKKLAETLGRK 280 290 300 310 320 pF1KB6 DLNSA >>NP_001180412 (OMIM: 602567) LIM and senescent cell ant (337 aa) initn: 2159 init1: 2159 opt: 2159 Z-score: 1560.0 bits: 297.1 E(85289): 3.7e-80 Smith-Waterman score: 2159; 85.6% identity (96.9% similar) in 326 aa overlap (29-354:12-337) 10 20 30 40 50 60 pF1KB6 MAARLGALAASGLYRRRQHRQSPPPATGNMSDALANAVCQRCQARFSPAERIVNSNGELY ::..:::.:.:.::.. :.:::.::::::::: NP_001 MLGVAAGMTHSNMANALASATCERCKGGFAPAEKIVNSNGELY 10 20 30 40 70 80 90 100 110 120 pF1KB6 HEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFIIGRVIKAMNNNWH ::.::::::::. ::::::::::::::::::::::::::: .:::::::::::::::.:: NP_001 HEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFIIGRVIKAMNNSWH 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB6 PGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVIDEQPLMFRS : ::::.::. :::.::::::::::::::::::::.::::::::.:: .::::::.:.. NP_001 PECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAIIDEQPLIFKN 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB6 DAYHPDHFNCTHCGKELTAEARELKGELYCLPCHDKMGVPICGACRRPIEGRVVNALGKQ : ::::::::..:::::::.::::::::::::::::::::::::::::::::::::.::: NP_001 DPYHPDHFNCANCGKELTADARELKGELYCLPCHDKMGVPICGACRRPIEGRVVNAMGKQ 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB6 WHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDVVSALNKAW ::::::::::::::::::::::.::::::::::::::::::..:..:::::::::::::: NP_001 WHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLFGDVCFHCNRVIEGDVVSALNKAW 230 240 250 260 270 280 310 320 330 340 350 360 pF1KB6 CVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEKFPLELKKRLKKLSELTSRKAQPKAT ::.::.:::::.::::::::::::::::::.::::::::::::::::.: .:: NP_001 CVNCFACSTCNTKLTLKNKFVEFDMKPVCKKCYEKFPLELKKRLKKLAETLGRK 290 300 310 320 330 pF1KB6 DLNSA >>NP_001180414 (OMIM: 602567) LIM and senescent cell ant (387 aa) initn: 2159 init1: 2159 opt: 2159 Z-score: 1559.4 bits: 297.2 E(85289): 4e-80 Smith-Waterman score: 2159; 85.6% identity (96.9% similar) in 326 aa overlap (29-354:62-387) 10 20 30 40 50 pF1KB6 MAARLGALAASGLYRRRQHRQSPPPATGNMSDALANAVCQRCQARFSPAERIVNSNGE ::..:::.:.:.::.. :.:::.::::::: NP_001 TEDERAVSKLQRRHSDVKVYKEFCDFYAKFNMANALASATCERCKGGFAPAEKIVNSNGE 40 50 60 70 80 90 60 70 80 90 100 110 pF1KB6 LYHEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFIIGRVIKAMNNN ::::.::::::::. ::::::::::::::::::::::::::: .:::::::::::::::. NP_001 LYHEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFIIGRVIKAMNNS 100 110 120 130 140 150 120 130 140 150 160 170 pF1KB6 WHPGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVIDEQPLMF ::: ::::.::. :::.::::::::::::::::::::.::::::::.:: .::::::.: NP_001 WHPECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAIIDEQPLIF 160 170 180 190 200 210 180 190 200 210 220 230 pF1KB6 RSDAYHPDHFNCTHCGKELTAEARELKGELYCLPCHDKMGVPICGACRRPIEGRVVNALG ..: ::::::::..:::::::.::::::::::::::::::::::::::::::::::::.: NP_001 KNDPYHPDHFNCANCGKELTADARELKGELYCLPCHDKMGVPICGACRRPIEGRVVNAMG 220 230 240 250 260 270 240 250 260 270 280 290 pF1KB6 KQWHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDVVSALNK ::::::::::::::::::::::::.::::::::::::::::::..:..:::::::::::: NP_001 KQWHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLFGDVCFHCNRVIEGDVVSALNK 280 290 300 310 320 330 300 310 320 330 340 350 pF1KB6 AWCVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEKFPLELKKRLKKLSELTSRKAQPK ::::.::.:::::.::::::::::::::::::.::::::::::::::::.: .:: NP_001 AWCVNCFACSTCNTKLTLKNKFVEFDMKPVCKKCYEKFPLELKKRLKKLAETLGRK 340 350 360 370 380 360 pF1KB6 ATDLNSA >>NP_004978 (OMIM: 602567) LIM and senescent cell antige (325 aa) initn: 2152 init1: 2152 opt: 2152 Z-score: 1555.2 bits: 296.2 E(85289): 6.9e-80 Smith-Waterman score: 2152; 85.5% identity (96.9% similar) in 325 aa overlap (30-354:1-325) 10 20 30 40 50 60 pF1KB6 MAARLGALAASGLYRRRQHRQSPPPATGNMSDALANAVCQRCQARFSPAERIVNSNGELY :..:::.:.:.::.. :.:::.::::::::: NP_004 MANALASATCERCKGGFAPAEKIVNSNGELY 10 20 30 70 80 90 100 110 120 pF1KB6 HEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFIIGRVIKAMNNNWH ::.::::::::. ::::::::::::::::::::::::::: .:::::::::::::::.:: NP_004 HEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFIIGRVIKAMNNSWH 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB6 PGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVIDEQPLMFRS : ::::.::. :::.::::::::::::::::::::.::::::::.:: .::::::.:.. NP_004 PECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAIIDEQPLIFKN 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB6 DAYHPDHFNCTHCGKELTAEARELKGELYCLPCHDKMGVPICGACRRPIEGRVVNALGKQ : ::::::::..:::::::.::::::::::::::::::::::::::::::::::::.::: NP_004 DPYHPDHFNCANCGKELTADARELKGELYCLPCHDKMGVPICGACRRPIEGRVVNAMGKQ 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB6 WHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDVVSALNKAW ::::::::::::::::::::::.::::::::::::::::::..:..:::::::::::::: NP_004 WHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLFGDVCFHCNRVIEGDVVSALNKAW 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB6 CVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEKFPLELKKRLKKLSELTSRKAQPKAT ::.::.:::::.::::::::::::::::::.::::::::::::::::.: .:: NP_004 CVNCFACSTCNTKLTLKNKFVEFDMKPVCKKCYEKFPLELKKRLKKLAETLGRK 280 290 300 310 320 pF1KB6 DLNSA >>NP_001180417 (OMIM: 602567) LIM and senescent cell ant (325 aa) initn: 2152 init1: 2152 opt: 2152 Z-score: 1555.2 bits: 296.2 E(85289): 6.9e-80 Smith-Waterman score: 2152; 85.5% identity (96.9% similar) in 325 aa overlap (30-354:1-325) 10 20 30 40 50 60 pF1KB6 MAARLGALAASGLYRRRQHRQSPPPATGNMSDALANAVCQRCQARFSPAERIVNSNGELY :..:::.:.:.::.. :.:::.::::::::: NP_001 MANALASATCERCKGGFAPAEKIVNSNGELY 10 20 30 70 80 90 100 110 120 pF1KB6 HEHCFVCAQCFRPFPEGLFYEFEGRKYCEHDFQMLFAPCCGSCGEFIIGRVIKAMNNNWH ::.::::::::. ::::::::::::::::::::::::::: .:::::::::::::::.:: NP_001 HEQCFVCAQCFQQFPEGLFYEFEGRKYCEHDFQMLFAPCCHQCGEFIIGRVIKAMNNSWH 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB6 PGCFRCELCDVELADLGFVKNAGRHLCRPCHNREKAKGLGKYICQRCHLVIDEQPLMFRS : ::::.::. :::.::::::::::::::::::::.::::::::.:: .::::::.:.. NP_001 PECFRCDLCQEVLADIGFVKNAGRHLCRPCHNREKARGLGKYICQKCHAIIDEQPLIFKN 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB6 DAYHPDHFNCTHCGKELTAEARELKGELYCLPCHDKMGVPICGACRRPIEGRVVNALGKQ : ::::::::..:::::::.::::::::::::::::::::::::::::::::::::.::: NP_001 DPYHPDHFNCANCGKELTADARELKGELYCLPCHDKMGVPICGACRRPIEGRVVNAMGKQ 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB6 WHVEHFVCAKCEKPFLGHRHYEKKGLAYCETHYNQLFGDVCYNCSHVIEGDVVSALNKAW ::::::::::::::::::::::.::::::::::::::::::..:..:::::::::::::: NP_001 WHVEHFVCAKCEKPFLGHRHYERKGLAYCETHYNQLFGDVCFHCNRVIEGDVVSALNKAW 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB6 CVSCFSCSTCNSKLTLKNKFVEFDMKPVCKRCYEKFPLELKKRLKKLSELTSRKAQPKAT ::.::.:::::.::::::::::::::::::.::::::::::::::::.: .:: NP_001 CVNCFACSTCNTKLTLKNKFVEFDMKPVCKKCYEKFPLELKKRLKKLAETLGRK 280 290 300 310 320 pF1KB6 DLNSA 365 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 23:14:00 2016 done: Fri Nov 4 23:14:01 2016 Total Scan time: 7.020 Total Display time: 0.010 Function used was FASTA [36.3.4 Apr, 2011]