FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6531, 366 aa 1>>>pF1KB6531 366 - 366 aa - 366 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.2058+/-0.000818; mu= 8.1957+/- 0.049 mean_var=109.4918+/-21.810, 0's: 0 Z-trim(111.0): 31 B-trim: 430 in 1/52 Lambda= 0.122570 statistics sampled from 11996 (12026) to 11996 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.739), E-opt: 0.2 (0.369), width: 16 Scan time: 3.170 The best scores are: opt bits E(32554) CCDS8861.1 TARBP2 gene_id:6895|Hs108|chr12 ( 366) 2424 439.0 3.1e-123 CCDS41791.1 TARBP2 gene_id:6895|Hs108|chr12 ( 345) 2284 414.2 8.4e-116 CCDS46460.1 PRKRA gene_id:8575|Hs108|chr2 ( 302) 332 69.0 6.1e-12 CCDS46461.1 PRKRA gene_id:8575|Hs108|chr2 ( 288) 329 68.5 8.4e-12 CCDS2279.1 PRKRA gene_id:8575|Hs108|chr2 ( 313) 329 68.5 9.1e-12 >>CCDS8861.1 TARBP2 gene_id:6895|Hs108|chr12 (366 aa) initn: 2424 init1: 2424 opt: 2424 Z-score: 2325.8 bits: 439.0 E(32554): 3.1e-123 Smith-Waterman score: 2424; 100.0% identity (100.0% similar) in 366 aa overlap (1-366:1-366) 10 20 30 40 50 60 pF1KB6 MSEEEQGSGTTTGCGLPSIEQMLAANPGKTPISLLQEYGTRIGKTPVYDLLKAEGQAHQP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS88 MSEEEQGSGTTTGCGLPSIEQMLAANPGKTPISLLQEYGTRIGKTPVYDLLKAEGQAHQP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 NFTFRVTVGDTSCTGQGPSKKAAKHKAAEVALKHLKGGSMLEPALEDSSSFSPLDSSLPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS88 NFTFRVTVGDTSCTGQGPSKKAAKHKAAEVALKHLKGGSMLEPALEDSSSFSPLDSSLPE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 DIPVFTAAAAATPVPSVVLTRSPPMELQPPVSPQQSECNPVGALQELVVQKGWRLPEYTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS88 DIPVFTAAAAATPVPSVVLTRSPPMELQPPVSPQQSECNPVGALQELVVQKGWRLPEYTV 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 TQESGPAHRKEFTMTCRVERFIEIGSGTSKKLAKRNAAAKMLLRVHTVPLDARDGNEVEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS88 TQESGPAHRKEFTMTCRVERFIEIGSGTSKKLAKRNAAAKMLLRVHTVPLDARDGNEVEP 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 DDDHFSIGVGSRLDGLRNRGPGCTWDSLRNSVGEKILSLRSCSLGSLGALGPACCRVLSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS88 DDDHFSIGVGSRLDGLRNRGPGCTWDSLRNSVGEKILSLRSCSLGSLGALGPACCRVLSE 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 LSEEQAFHVSYLDIEELSLSGLCQCLVELSTQPATVCHGSATTREAARGEAARRALQYLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS88 LSEEQAFHVSYLDIEELSLSGLCQCLVELSTQPATVCHGSATTREAARGEAARRALQYLK 310 320 330 340 350 360 pF1KB6 IMAGSK :::::: CCDS88 IMAGSK >>CCDS41791.1 TARBP2 gene_id:6895|Hs108|chr12 (345 aa) initn: 2284 init1: 2284 opt: 2284 Z-score: 2192.4 bits: 414.2 E(32554): 8.4e-116 Smith-Waterman score: 2284; 100.0% identity (100.0% similar) in 345 aa overlap (22-366:1-345) 10 20 30 40 50 60 pF1KB6 MSEEEQGSGTTTGCGLPSIEQMLAANPGKTPISLLQEYGTRIGKTPVYDLLKAEGQAHQP ::::::::::::::::::::::::::::::::::::::: CCDS41 MLAANPGKTPISLLQEYGTRIGKTPVYDLLKAEGQAHQP 10 20 30 70 80 90 100 110 120 pF1KB6 NFTFRVTVGDTSCTGQGPSKKAAKHKAAEVALKHLKGGSMLEPALEDSSSFSPLDSSLPE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 NFTFRVTVGDTSCTGQGPSKKAAKHKAAEVALKHLKGGSMLEPALEDSSSFSPLDSSLPE 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB6 DIPVFTAAAAATPVPSVVLTRSPPMELQPPVSPQQSECNPVGALQELVVQKGWRLPEYTV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 DIPVFTAAAAATPVPSVVLTRSPPMELQPPVSPQQSECNPVGALQELVVQKGWRLPEYTV 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB6 TQESGPAHRKEFTMTCRVERFIEIGSGTSKKLAKRNAAAKMLLRVHTVPLDARDGNEVEP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 TQESGPAHRKEFTMTCRVERFIEIGSGTSKKLAKRNAAAKMLLRVHTVPLDARDGNEVEP 160 170 180 190 200 210 250 260 270 280 290 300 pF1KB6 DDDHFSIGVGSRLDGLRNRGPGCTWDSLRNSVGEKILSLRSCSLGSLGALGPACCRVLSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 DDDHFSIGVGSRLDGLRNRGPGCTWDSLRNSVGEKILSLRSCSLGSLGALGPACCRVLSE 220 230 240 250 260 270 310 320 330 340 350 360 pF1KB6 LSEEQAFHVSYLDIEELSLSGLCQCLVELSTQPATVCHGSATTREAARGEAARRALQYLK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS41 LSEEQAFHVSYLDIEELSLSGLCQCLVELSTQPATVCHGSATTREAARGEAARRALQYLK 280 290 300 310 320 330 pF1KB6 IMAGSK :::::: CCDS41 IMAGSK 340 >>CCDS46460.1 PRKRA gene_id:8575|Hs108|chr2 (302 aa) initn: 949 init1: 325 opt: 332 Z-score: 327.9 bits: 69.0 E(32554): 6.1e-12 Smith-Waterman score: 865; 44.3% identity (67.8% similar) in 357 aa overlap (10-366:3-302) 10 20 30 40 50 60 pF1KB6 MSEEEQGSGTTTGCGLPSIEQMLAANPGKTPISLLQEYGTRIGKTPVYDLLKAEGQAHQP .: ::. :. .:..:.::::::..:.::: . . :::. ... : : : CCDS46 MQSTPFCGFCSLGKMITAKPGKTPIQVLHEYGMKTKNIPVYECERSDVQIHVP 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 NFTFRVTVGDTSCTGQGPSKKAAKHKAAEVALKHLKGGSMLEPALEDSSSFSPLDSSLPE .::::::::: .:::.: ::: :::.:::.:.. ::... . :. : :: .:. CCDS46 TFTFRVTVGDITCTGEGTSKKLAKHRAAEAAINILKANASICFAVPD-----PL---MPD 60 70 80 90 100 130 140 150 160 170 180 pF1KB6 DIPVFTAAAAATPVPSVVLTRSPPMELQPPVSPQQSECNPVGALQELVVQKGWRLPEYTV :: ..: .: ::.:.::::....::::::::. CCDS46 --------------PS----KQPKNQL-----------NPIGSLQELAIHHGWRLPEYTL 110 120 130 190 200 210 220 230 240 pF1KB6 TQESGPAHRKEFTMTCRVERFIEIGSGTSKKLAKRNAAAKMLLRVHTVPLDARDGNEVEP .::.::::..:.: ::.: :.: :.:.::: :::::: :.: . ... : CCDS46 SQEGGPAHKREYTTICRLESFMETGKGASKKQAKRNAAEKFLAKF----------SNISP 140 150 160 170 180 250 260 270 280 290 300 pF1KB6 DDDHFSIGVGSRLDGLRNRGPGCTWDSLRNSVGEKILSLRSCSLGSLGALGPACCRVLSE .. :.: : .. ... :::: ::::: :::: :. :: :. ..::: CCDS46 EN-HIS------LTNVVGHSLGCTWHSLRNSPGEKINLLKR-SLLSIPNTDYI--QLLSE 190 200 210 220 230 310 320 330 340 350 360 pF1KB6 LSEEQAFHVSYLDIEELSLSGLCQCLVELSTQPATVCHGSATTREAARGEAARRALQYLK ...::.:...::::.::: .: :::.::::.: ::::::. . :...::. :::::: CCDS46 IAKEQGFNITYLDIDELSANGQYQCLAELSTSPITVCHGSGISCGNAQSDAAHNALQYLK 240 250 260 270 280 290 pF1KB6 IMAGSK :.: : CCDS46 IIAERK 300 >>CCDS46461.1 PRKRA gene_id:8575|Hs108|chr2 (288 aa) initn: 925 init1: 320 opt: 329 Z-score: 325.4 bits: 68.5 E(32554): 8.4e-12 Smith-Waterman score: 839; 44.6% identity (67.8% similar) in 345 aa overlap (22-366:1-288) 10 20 30 40 50 60 pF1KB6 MSEEEQGSGTTTGCGLPSIEQMLAANPGKTPISLLQEYGTRIGKTPVYDLLKAEGQAHQP :..:.::::::..:.::: . . :::. ... : : : CCDS46 MITAKPGKTPIQVLHEYGMKTKNIPVYECERSDVQIHVP 10 20 30 70 80 90 100 110 120 pF1KB6 NFTFRVTVGDTSCTGQGPSKKAAKHKAAEVALKHLKGGSMLEPALEDSSSFSPLDSSLPE .::::::::: .:::.: ::: :::.:::.:.. ::... . :. : :: .:. CCDS46 TFTFRVTVGDITCTGEGTSKKLAKHRAAEAAINILKANASICFAVPD-----PL---MPD 40 50 60 70 80 90 130 140 150 160 170 180 pF1KB6 DIPVFTAAAAATPVPSVVLTRSPPMELQPPVSPQQSECNPVGALQELVVQKGWRLPEYTV :: ..: .: ::.:.::::....::::::::. CCDS46 --------------PS----KQPKNQL-----------NPIGSLQELAIHHGWRLPEYTL 100 110 120 190 200 210 220 230 240 pF1KB6 TQESGPAHRKEFTMTCRVERFIEIGSGTSKKLAKRNAAAKMLLRVHTVPLDARDGNEVEP .::.::::..:.: ::.: :.: :.:.::: :::::: :.: . ... : CCDS46 SQEGGPAHKREYTTICRLESFMETGKGASKKQAKRNAAEKFLAKF----------SNISP 130 140 150 160 170 250 260 270 280 290 300 pF1KB6 DDDHFSIGVGSRLDGLRNRGPGCTWDSLRNSVGEKILSLRSCSLGSLGALGPACCRVLSE .. :.: : .. ... :::: ::::: :::: :. :: :. ..::: CCDS46 EN-HIS------LTNVVGHSLGCTWHSLRNSPGEKINLLKR-SLLSIPNTDYI--QLLSE 180 190 200 210 220 310 320 330 340 350 360 pF1KB6 LSEEQAFHVSYLDIEELSLSGLCQCLVELSTQPATVCHGSATTREAARGEAARRALQYLK ...::.:...::::.::: .: :::.::::.: ::::::. . :...::. :::::: CCDS46 IAKEQGFNITYLDIDELSANGQYQCLAELSTSPITVCHGSGISCGNAQSDAAHNALQYLK 230 240 250 260 270 280 pF1KB6 IMAGSK :.: : CCDS46 IIAERK >>CCDS2279.1 PRKRA gene_id:8575|Hs108|chr2 (313 aa) initn: 931 init1: 320 opt: 329 Z-score: 324.8 bits: 68.5 E(32554): 9.1e-12 Smith-Waterman score: 848; 44.3% identity (67.6% similar) in 352 aa overlap (15-366:19-313) 10 20 30 40 50 pF1KB6 MSEEEQGSGTTTGCGLPSIEQMLAANPGKTPISLLQEYGTRIGKTPVYDLLKAEGQ : :. .:..:.::::::..:.::: . . :::. ... : CCDS22 MSQSRHRAEAPPLEREDSGTFSLGKMITAKPGKTPIQVLHEYGMKTKNIPVYECERSDVQ 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 AHQPNFTFRVTVGDTSCTGQGPSKKAAKHKAAEVALKHLKGGSMLEPALEDSSSFSPLDS : :.::::::::: .:::.: ::: :::.:::.:.. ::... . :. : :: CCDS22 IHVPTFTFRVTVGDITCTGEGTSKKLAKHRAAEAAINILKANASICFAVPD-----PL-- 70 80 90 100 110 120 130 140 150 160 170 pF1KB6 SLPEDIPVFTAAAAATPVPSVVLTRSPPMELQPPVSPQQSECNPVGALQELVVQKGWRLP .:. :: :: ... ::.:.::::....::::: CCDS22 -MPD--------------PS----------KQP-----KNQLNPIGSLQELAIHHGWRLP 120 130 140 180 190 200 210 220 230 pF1KB6 EYTVTQESGPAHRKEFTMTCRVERFIEIGSGTSKKLAKRNAAAKMLLRVHTVPLDARDGN :::..::.::::..:.: ::.: :.: :.:.::: :::::: :.: . . CCDS22 EYTLSQEGGPAHKREYTTICRLESFMETGKGASKKQAKRNAAEKFLAKF----------S 150 160 170 180 190 240 250 260 270 280 290 pF1KB6 EVEPDDDHFSIGVGSRLDGLRNRGPGCTWDSLRNSVGEKILSLRSCSLGSLGALGPACCR .. :.. :.: : .. ... :::: ::::: :::: :. :: :. . CCDS22 NISPEN-HIS------LTNVVGHSLGCTWHSLRNSPGEKINLLKR-SLLSIPNTDYI--Q 200 210 220 230 240 300 310 320 330 340 350 pF1KB6 VLSELSEEQAFHVSYLDIEELSLSGLCQCLVELSTQPATVCHGSATTREAARGEAARRAL .:::...::.:...::::.::: .: :::.::::.: ::::::. . :...::. :: CCDS22 LLSEIAKEQGFNITYLDIDELSANGQYQCLAELSTSPITVCHGSGISCGNAQSDAAHNAL 250 260 270 280 290 300 360 pF1KB6 QYLKIMAGSK :::::.: : CCDS22 QYLKIIAERK 310 366 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 01:17:27 2016 done: Sat Nov 5 01:17:28 2016 Total Scan time: 3.170 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]