FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6537, 367 aa 1>>>pF1KB6537 367 - 367 aa - 367 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.8679+/-0.000296; mu= 11.1459+/- 0.019 mean_var=114.4240+/-22.712, 0's: 0 Z-trim(119.7): 19 B-trim: 334 in 1/60 Lambda= 0.119899 statistics sampled from 34123 (34142) to 34123 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.741), E-opt: 0.2 (0.4), width: 16 Scan time: 6.930 The best scores are: opt bits E(85289) NP_005008 (OMIM: 123695,608940) choline-phosphate ( 367) 2472 437.9 1.8e-122 NP_001299602 (OMIM: 123695,608940) choline-phospha ( 367) 2472 437.9 1.8e-122 NP_001156736 (OMIM: 300948) choline-phosphate cyti ( 351) 1654 296.3 6.8e-80 NP_004836 (OMIM: 300948) choline-phosphate cytidyl ( 369) 1647 295.1 1.6e-79 NP_001156737 (OMIM: 300948) choline-phosphate cyti ( 330) 1533 275.4 1.3e-73 XP_016885466 (OMIM: 300948) PREDICTED: choline-pho ( 273) 1403 252.9 6.5e-67 NP_001317447 (OMIM: 602679) ethanolamine-phosphate ( 367) 344 69.8 1.2e-11 XP_006722350 (OMIM: 602679) PREDICTED: ethanolamin ( 385) 344 69.8 1.2e-11 NP_002852 (OMIM: 602679) ethanolamine-phosphate cy ( 389) 344 69.8 1.2e-11 NP_001171846 (OMIM: 602679) ethanolamine-phosphate ( 407) 344 69.8 1.3e-11 XP_016880401 (OMIM: 602679) PREDICTED: ethanolamin ( 220) 304 62.7 9.2e-10 NP_001243362 (OMIM: 602679) ethanolamine-phosphate ( 335) 304 62.8 1.3e-09 NP_001269133 (OMIM: 602679) ethanolamine-phosphate ( 357) 292 60.8 5.8e-09 XP_016880400 (OMIM: 602679) PREDICTED: ethanolamin ( 357) 292 60.8 5.8e-09 XP_005256443 (OMIM: 602679) PREDICTED: ethanolamin ( 375) 292 60.8 6e-09 XP_005256444 (OMIM: 602679) PREDICTED: ethanolamin ( 375) 292 60.8 6e-09 NP_001243363 (OMIM: 602679) ethanolamine-phosphate ( 348) 218 47.9 4e-05 NP_001243364 (OMIM: 602679) ethanolamine-phosphate ( 311) 183 41.9 0.0024 NP_001269132 (OMIM: 602679) ethanolamine-phosphate ( 311) 183 41.9 0.0024 >>NP_005008 (OMIM: 123695,608940) choline-phosphate cyti (367 aa) initn: 2472 init1: 2472 opt: 2472 Z-score: 2319.7 bits: 437.9 E(85289): 1.8e-122 Smith-Waterman score: 2472; 100.0% identity (100.0% similar) in 367 aa overlap (1-367:1-367) 10 20 30 40 50 60 pF1KB6 MDAQCSAKVNARKRRKEAPGPNGATEEDGVPSKVQRCAVGLRQPAPFSDEIEVDFSKPYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 MDAQCSAKVNARKRRKEAPGPNGATEEDGVPSKVQRCAVGLRQPAPFSDEIEVDFSKPYV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 RVTMEEASRGTPCERPVRVYADGIFDLFHSGHARALMQAKNLFPNTYLIVGVCSDELTHN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 RVTMEEASRGTPCERPVRVYADGIFDLFHSGHARALMQAKNLFPNTYLIVGVCSDELTHN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 FKGFTVMNENERYDAVQHCRYVDEVVRNAPWTLTPEFLAEHRIDFVAHDDIPYSSAGSDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 FKGFTVMNENERYDAVQHCRYVDEVVRNAPWTLTPEFLAEHRIDFVAHDDIPYSSAGSDD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 VYKHIKEAGMFAPTQRTEGISTSDIITRIVRDYDVYARRNLQRGYTAKELNVSFINEKKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 VYKHIKEAGMFAPTQRTEGISTSDIITRIVRDYDVYARRNLQRGYTAKELNVSFINEKKY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 HLQERVDKVKKKVKDVEEKSKEFVQKVEEKSIDLIQKWEEKSREFIGSFLEMFGPEGALK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 HLQERVDKVKKKVKDVEEKSKEFVQKVEEKSIDLIQKWEEKSREFIGSFLEMFGPEGALK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 HMLKEGKGRMLQAISPKQSPSSSPTRERSPSPSFRWPFSGKTSPPCSPANLSRHKAAAYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_005 HMLKEGKGRMLQAISPKQSPSSSPTRERSPSPSFRWPFSGKTSPPCSPANLSRHKAAAYD 310 320 330 340 350 360 pF1KB6 ISEDEED ::::::: NP_005 ISEDEED >>NP_001299602 (OMIM: 123695,608940) choline-phosphate c (367 aa) initn: 2472 init1: 2472 opt: 2472 Z-score: 2319.7 bits: 437.9 E(85289): 1.8e-122 Smith-Waterman score: 2472; 100.0% identity (100.0% similar) in 367 aa overlap (1-367:1-367) 10 20 30 40 50 60 pF1KB6 MDAQCSAKVNARKRRKEAPGPNGATEEDGVPSKVQRCAVGLRQPAPFSDEIEVDFSKPYV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDAQCSAKVNARKRRKEAPGPNGATEEDGVPSKVQRCAVGLRQPAPFSDEIEVDFSKPYV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 RVTMEEASRGTPCERPVRVYADGIFDLFHSGHARALMQAKNLFPNTYLIVGVCSDELTHN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RVTMEEASRGTPCERPVRVYADGIFDLFHSGHARALMQAKNLFPNTYLIVGVCSDELTHN 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 FKGFTVMNENERYDAVQHCRYVDEVVRNAPWTLTPEFLAEHRIDFVAHDDIPYSSAGSDD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 FKGFTVMNENERYDAVQHCRYVDEVVRNAPWTLTPEFLAEHRIDFVAHDDIPYSSAGSDD 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 VYKHIKEAGMFAPTQRTEGISTSDIITRIVRDYDVYARRNLQRGYTAKELNVSFINEKKY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 VYKHIKEAGMFAPTQRTEGISTSDIITRIVRDYDVYARRNLQRGYTAKELNVSFINEKKY 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 HLQERVDKVKKKVKDVEEKSKEFVQKVEEKSIDLIQKWEEKSREFIGSFLEMFGPEGALK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HLQERVDKVKKKVKDVEEKSKEFVQKVEEKSIDLIQKWEEKSREFIGSFLEMFGPEGALK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 HMLKEGKGRMLQAISPKQSPSSSPTRERSPSPSFRWPFSGKTSPPCSPANLSRHKAAAYD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 HMLKEGKGRMLQAISPKQSPSSSPTRERSPSPSFRWPFSGKTSPPCSPANLSRHKAAAYD 310 320 330 340 350 360 pF1KB6 ISEDEED ::::::: NP_001 ISEDEED >>NP_001156736 (OMIM: 300948) choline-phosphate cytidyly (351 aa) initn: 1606 init1: 1606 opt: 1654 Z-score: 1555.3 bits: 296.3 E(85289): 6.8e-80 Smith-Waterman score: 1654; 72.3% identity (87.6% similar) in 347 aa overlap (26-367:10-349) 10 20 30 40 50 60 pF1KB6 MDAQCSAKVNARKRRKEAPGPNGATEEDGVPSKVQRCAVGLRQPAPFSDEIEVDFSKPYV :::. .. : . : ::::.:: . . . :. NP_001 MVGHQECIMEEDNRAPQLWRKT--LTAPAPFADETNCQCQAPHE 10 20 30 40 70 80 90 100 110 120 pF1KB6 RVTMEEASRGTPCERPVRVYADGIFDLFHSGHARALMQAKNLFPNTYLIVGVCSDELTHN ..:. .: ::: .::::::::::::::::::::::::::.::::.::.::::::.:::. NP_001 KLTIAQARLGTPADRPVRVYADGIFDLFHSGHARALMQAKTLFPNSYLLVGVCSDDLTHK 50 60 70 80 90 100 130 140 150 160 170 180 pF1KB6 FKGFTVMNENERYDAVQHCRYVDEVVRNAPWTLTPEFLAEHRIDFVAHDDIPYSSAGSDD ::::::::: :::.:..::::::::.:.:::::::::: .:.:::::::::::::::::: NP_001 FKGFTVMNEAERYEALRHCRYVDEVIRDAPWTLTPEFLEKHKIDFVAHDDIPYSSAGSDD 110 120 130 140 150 160 190 200 210 220 230 240 pF1KB6 VYKHIKEAGMFAPTQRTEGISTSDIITRIVRDYDVYARRNLQRGYTAKELNVSFINEKKY :::::::::::.::::::::::::::::::::::::::::::::::::::::::::::.: NP_001 VYKHIKEAGMFVPTQRTEGISTSDIITRIVRDYDVYARRNLQRGYTAKELNVSFINEKRY 170 180 190 200 210 220 250 260 270 280 290 300 pF1KB6 HLQERVDKVKKKVKDVEEKSKEFVQKVEEKSIDLIQKWEEKSREFIGSFLEMFGPEGALK ..:..:::.:.:::.:::.:::::..::::: :::::::::::::::.:::.:::.:: : NP_001 RFQNQVDKMKEKVKNVEERSKEFVNRVEEKSHDLIQKWEEKSREFIGNFLELFGPDGAWK 230 240 250 260 270 280 310 320 330 340 350 pF1KB6 HMLKEGKGRMLQAISPKQSPSSSPTRERSPS----PSFRW-PFSGKTSPPCSPANLSRHK .:..: ..:::::.:::::: ::::: :::: :.: : :. ::::: :: : NP_001 QMFQERSSRMLQALSPKQSPVSSPTRSRSPSRSPSPTFSWLPL--KTSPPSSPKAAS--- 290 300 310 320 330 360 pF1KB6 AAAYDISEDEED :. ..:: .:: NP_001 ASISSMSEGDEDEK 340 350 >>NP_004836 (OMIM: 300948) choline-phosphate cytidylyltr (369 aa) initn: 1606 init1: 1606 opt: 1647 Z-score: 1548.5 bits: 295.1 E(85289): 1.6e-79 Smith-Waterman score: 1647; 74.4% identity (89.2% similar) in 332 aa overlap (41-367:41-367) 20 30 40 50 60 70 pF1KB6 ARKRRKEAPGPNGATEEDGVPSKVQRCAVGLRQPAPFSDEIEVDFSKPYVRVTMEEASRG : ::::.:: . . . :. ..:. .: : NP_004 ETGIPKSLSNEPPSETMEEIEHTCPQPRLTLTAPAPFADETNCQCQAPHEKLTIAQARLG 20 30 40 50 60 70 80 90 100 110 120 130 pF1KB6 TPCERPVRVYADGIFDLFHSGHARALMQAKNLFPNTYLIVGVCSDELTHNFKGFTVMNEN :: .::::::::::::::::::::::::::.::::.::.::::::.:::.::::::::: NP_004 TPADRPVRVYADGIFDLFHSGHARALMQAKTLFPNSYLLVGVCSDDLTHKFKGFTVMNEA 80 90 100 110 120 130 140 150 160 170 180 190 pF1KB6 ERYDAVQHCRYVDEVVRNAPWTLTPEFLAEHRIDFVAHDDIPYSSAGSDDVYKHIKEAGM :::.:..::::::::.:.:::::::::: .:.:::::::::::::::::::::::::::: NP_004 ERYEALRHCRYVDEVIRDAPWTLTPEFLEKHKIDFVAHDDIPYSSAGSDDVYKHIKEAGM 140 150 160 170 180 190 200 210 220 230 240 250 pF1KB6 FAPTQRTEGISTSDIITRIVRDYDVYARRNLQRGYTAKELNVSFINEKKYHLQERVDKVK :.::::::::::::::::::::::::::::::::::::::::::::::.:..:..:::.: NP_004 FVPTQRTEGISTSDIITRIVRDYDVYARRNLQRGYTAKELNVSFINEKRYRFQNQVDKMK 200 210 220 230 240 250 260 270 280 290 300 310 pF1KB6 KKVKDVEEKSKEFVQKVEEKSIDLIQKWEEKSREFIGSFLEMFGPEGALKHMLKEGKGRM .:::.:::.:::::..::::: :::::::::::::::.:::.:::.:: :.:..: ..:: NP_004 EKVKNVEERSKEFVNRVEEKSHDLIQKWEEKSREFIGNFLELFGPDGAWKQMFQERSSRM 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 LQAISPKQSPSSSPTRERSPS----PSFRW-PFSGKTSPPCSPANLSRHKAAAYDISEDE :::.:::::: ::::: :::: :.: : :. ::::: :: : :. ..:: . NP_004 LQALSPKQSPVSSPTRSRSPSRSPSPTFSWLPL--KTSPPSSPKAAS---ASISSMSEGD 320 330 340 350 360 pF1KB6 ED :: NP_004 EDEK >>NP_001156737 (OMIM: 300948) choline-phosphate cytidyly (330 aa) initn: 1622 init1: 1530 opt: 1533 Z-score: 1442.6 bits: 275.4 E(85289): 1.3e-73 Smith-Waterman score: 1533; 77.8% identity (93.4% similar) in 288 aa overlap (41-328:41-328) 20 30 40 50 60 70 pF1KB6 ARKRRKEAPGPNGATEEDGVPSKVQRCAVGLRQPAPFSDEIEVDFSKPYVRVTMEEASRG : ::::.:: . . . :. ..:. .: : NP_001 ETGIPKSLSNEPPSETMEEIEHTCPQPRLTLTAPAPFADETNCQCQAPHEKLTIAQARLG 20 30 40 50 60 70 80 90 100 110 120 130 pF1KB6 TPCERPVRVYADGIFDLFHSGHARALMQAKNLFPNTYLIVGVCSDELTHNFKGFTVMNEN :: .::::::::::::::::::::::::::.::::.::.::::::.:::.::::::::: NP_001 TPADRPVRVYADGIFDLFHSGHARALMQAKTLFPNSYLLVGVCSDDLTHKFKGFTVMNEA 80 90 100 110 120 130 140 150 160 170 180 190 pF1KB6 ERYDAVQHCRYVDEVVRNAPWTLTPEFLAEHRIDFVAHDDIPYSSAGSDDVYKHIKEAGM :::.:..::::::::.:.:::::::::: .:.:::::::::::::::::::::::::::: NP_001 ERYEALRHCRYVDEVIRDAPWTLTPEFLEKHKIDFVAHDDIPYSSAGSDDVYKHIKEAGM 140 150 160 170 180 190 200 210 220 230 240 250 pF1KB6 FAPTQRTEGISTSDIITRIVRDYDVYARRNLQRGYTAKELNVSFINEKKYHLQERVDKVK :.::::::::::::::::::::::::::::::::::::::::::::::.:..:..:::.: NP_001 FVPTQRTEGISTSDIITRIVRDYDVYARRNLQRGYTAKELNVSFINEKRYRFQNQVDKMK 200 210 220 230 240 250 260 270 280 290 300 310 pF1KB6 KKVKDVEEKSKEFVQKVEEKSIDLIQKWEEKSREFIGSFLEMFGPEGALKHMLKEGKGRM .:::.:::.:::::..::::: :::::::::::::::.:::.:::.:: :.:..: ..:: NP_001 EKVKNVEERSKEFVNRVEEKSHDLIQKWEEKSREFIGNFLELFGPDGAWKQMFQERSSRM 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 LQAISPKQSPSSSPTRERSPSPSFRWPFSGKTSPPCSPANLSRHKAAAYDISEDEED :::.:::::: .: .: : NP_001 LQALSPKQSPLKSWARCRDF 320 330 >>XP_016885466 (OMIM: 300948) PREDICTED: choline-phospha (273 aa) initn: 1362 init1: 1362 opt: 1403 Z-score: 1322.3 bits: 252.9 E(85289): 6.5e-67 Smith-Waterman score: 1403; 76.8% identity (90.9% similar) in 276 aa overlap (97-367:1-271) 70 80 90 100 110 120 pF1KB6 ASRGTPCERPVRVYADGIFDLFHSGHARALMQAKNLFPNTYLIVGVCSDELTHNFKGFTV ::::.::::.::.::::::.:::.:::::: XP_016 MQAKTLFPNSYLLVGVCSDDLTHKFKGFTV 10 20 30 130 140 150 160 170 180 pF1KB6 MNENERYDAVQHCRYVDEVVRNAPWTLTPEFLAEHRIDFVAHDDIPYSSAGSDDVYKHIK ::: :::.:..::::::::.:.:::::::::: .:.:::::::::::::::::::::::: XP_016 MNEAERYEALRHCRYVDEVIRDAPWTLTPEFLEKHKIDFVAHDDIPYSSAGSDDVYKHIK 40 50 60 70 80 90 190 200 210 220 230 240 pF1KB6 EAGMFAPTQRTEGISTSDIITRIVRDYDVYARRNLQRGYTAKELNVSFINEKKYHLQERV :::::.::::::::::::::::::::::::::::::::::::::::::::::.:..:..: XP_016 EAGMFVPTQRTEGISTSDIITRIVRDYDVYARRNLQRGYTAKELNVSFINEKRYRFQNQV 100 110 120 130 140 150 250 260 270 280 290 300 pF1KB6 DKVKKKVKDVEEKSKEFVQKVEEKSIDLIQKWEEKSREFIGSFLEMFGPEGALKHMLKEG ::.:.:::.:::.:::::..::::: :::::::::::::::.:::.:::.:: :.:..: XP_016 DKMKEKVKNVEERSKEFVNRVEEKSHDLIQKWEEKSREFIGNFLELFGPDGAWKQMFQER 160 170 180 190 200 210 310 320 330 340 350 360 pF1KB6 KGRMLQAISPKQSPSSSPTRERSPS----PSFRW-PFSGKTSPPCSPANLSRHKAAAYDI ..:::::.:::::: ::::: :::: :.: : :. ::::: :: : :. .. XP_016 SSRMLQALSPKQSPVSSPTRSRSPSRSPSPTFSWLPL--KTSPPSSPKAAS---ASISSM 220 230 240 250 260 pF1KB6 SEDEED :: .:: XP_016 SEGDEDEK 270 >>NP_001317447 (OMIM: 602679) ethanolamine-phosphate cyt (367 aa) initn: 359 init1: 254 opt: 344 Z-score: 330.4 bits: 69.8 E(85289): 1.2e-11 Smith-Waterman score: 344; 40.8% identity (66.9% similar) in 142 aa overlap (70-210:16-154) 40 50 60 70 80 90 pF1KB6 GLRQPAPFSDEIEVDFSKPYVRVTMEEASRGTPCERPVRVYADGIFDLFHSGHARALMQA : .: :::. :: .:. : ::. : :: NP_001 MIRNGRGAAGGAEQPGPGGRRAVRVWCDGCYDMVHYGHSNQLRQA 10 20 30 40 100 110 120 130 140 150 pF1KB6 KNLFPNTYLIVGVCSDELTHNFKGFTVMNENERYDAVQHCRYVDEVVRNAPWTLTPEFLA . . . :::::: .:: . :: :....::: :: ..::::: ::.. : : : NP_001 RAM--GDYLIVGVHTDEEIAKHKGPPVFTQEERYKMVQAIKWVDEVVPAAPYVTTLETLD 50 60 70 80 90 100 160 170 180 190 200 210 pF1KB6 EHRIDFVAH-DDIPYSSAGSDDVYKHIKEAGMFAPTQRTEGISTSDIITRIVRDYDVYAR .. :: .: .:: . : : .:...:.:: . .::.:.::.:.. :.. NP_001 KYNCDFCVHGNDITLTVDGRD-TYEEVKQAGRYRECKRTQGVSTTDLVGRMLLVTKAHHS 110 120 130 140 150 160 220 230 240 250 260 270 pF1KB6 RNLQRGYTAKELNVSFINEKKYHLQERVDKVKKKVKDVEEKSKEFVQKVEEKSIDLIQKW NP_001 SQEMSSEYREYADSFGKCPGGRNPWTGVSQFLQTSQKIIQFASGKEPQPGETVIYVAGAF 170 180 190 200 210 220 >-- initn: 212 init1: 118 opt: 214 Z-score: 208.9 bits: 47.3 E(85289): 6.8e-05 Smith-Waterman score: 232; 31.4% identity (56.2% similar) in 169 aa overlap (64-230:201-346) 40 50 60 70 80 90 pF1KB6 VQRCAVGLRQPAPFSDEIEVDFSKPYVRVTMEEASRGTPCERPVRVYADGIFDLFHSGHA .. :: : . .:. : ::::: ::. NP_001 REYADSFGKCPGGRNPWTGVSQFLQTSQKIIQFASGKEPQPGETVIYVAGAFDLFHIGHV 180 190 200 210 220 230 100 110 120 130 140 150 pF1KB6 RALMQAKNLFPNTYLIVGVCSDELTHNFKG--FTVMNENERYDAVQHCRYVDEVVRNAPW : ... : :.:.:. :. ....:: . .:: .:: .: ::::.::: .::. NP_001 DFLEKVHRLAERPYIIAGLHFDQEVNHYKGKNYPIMNLHERTLSVLACRYVSEVVIGAPY 240 250 260 270 280 290 160 170 180 190 200 210 pF1KB6 TLTPEFLAEHRIDFVAHDDIPYSSAGSDDVYKHIKEAGMFAPTQRTEGISTSDIITRIVR ..: :.:. : .:. :. :.: . ...:. :. ::. NP_001 AVTAELLS--------H-------------FKEPKRRGIFRQIDSGSNLTTDLIVQRIIT 300 310 320 220 230 240 250 260 270 pF1KB6 DYDVYARRNLQRGYTAKELNVSFINEKKYHLQERVDKVKKKVKDVEEKSKEFVQKVEEKS . : :: .. :::: NP_001 NRLEYEARNQKK--EAKELAFLEAARQQAAQPLGERDGDF 330 340 350 360 >>XP_006722350 (OMIM: 602679) PREDICTED: ethanolamine-ph (385 aa) initn: 337 init1: 254 opt: 344 Z-score: 330.1 bits: 69.8 E(85289): 1.2e-11 Smith-Waterman score: 344; 40.8% identity (66.9% similar) in 142 aa overlap (70-210:16-154) 40 50 60 70 80 90 pF1KB6 GLRQPAPFSDEIEVDFSKPYVRVTMEEASRGTPCERPVRVYADGIFDLFHSGHARALMQA : .: :::. :: .:. : ::. : :: XP_006 MIRNGRGAAGGAEQPGPGGRRAVRVWCDGCYDMVHYGHSNQLRQA 10 20 30 40 100 110 120 130 140 150 pF1KB6 KNLFPNTYLIVGVCSDELTHNFKGFTVMNENERYDAVQHCRYVDEVVRNAPWTLTPEFLA . . . :::::: .:: . :: :....::: :: ..::::: ::.. : : : XP_006 RAM--GDYLIVGVHTDEEIAKHKGPPVFTQEERYKMVQAIKWVDEVVPAAPYVTTLETLD 50 60 70 80 90 100 160 170 180 190 200 210 pF1KB6 EHRIDFVAH-DDIPYSSAGSDDVYKHIKEAGMFAPTQRTEGISTSDIITRIVRDYDVYAR .. :: .: .:: . : : .:...:.:: . .::.:.::.:.. :.. XP_006 KYNCDFCVHGNDITLTVDGRD-TYEEVKQAGRYRECKRTQGVSTTDLVGRMLLVTKAHHS 110 120 130 140 150 160 220 230 240 250 260 270 pF1KB6 RNLQRGYTAKELNVSFINEKKYHLQERVDKVKKKVKDVEEKSKEFVQKVEEKSIDLIQKW XP_006 SQEMSSEYREYADSFGKPPHPIPAGDILSSEGCSQCPGGRNPWTGVSQFLQTSQKIIQFA 170 180 190 200 210 220 >-- initn: 212 init1: 118 opt: 214 Z-score: 208.6 bits: 47.3 E(85289): 7.1e-05 Smith-Waterman score: 232; 31.4% identity (56.2% similar) in 169 aa overlap (64-230:219-364) 40 50 60 70 80 90 pF1KB6 VQRCAVGLRQPAPFSDEIEVDFSKPYVRVTMEEASRGTPCERPVRVYADGIFDLFHSGHA .. :: : . .:. : ::::: ::. XP_006 ILSSEGCSQCPGGRNPWTGVSQFLQTSQKIIQFASGKEPQPGETVIYVAGAFDLFHIGHV 190 200 210 220 230 240 100 110 120 130 140 150 pF1KB6 RALMQAKNLFPNTYLIVGVCSDELTHNFKG--FTVMNENERYDAVQHCRYVDEVVRNAPW : ... : :.:.:. :. ....:: . .:: .:: .: ::::.::: .::. XP_006 DFLEKVHRLAERPYIIAGLHFDQEVNHYKGKNYPIMNLHERTLSVLACRYVSEVVIGAPY 250 260 270 280 290 300 160 170 180 190 200 210 pF1KB6 TLTPEFLAEHRIDFVAHDDIPYSSAGSDDVYKHIKEAGMFAPTQRTEGISTSDIITRIVR ..: :.:. : .:. :. :.: . ...:. :. ::. XP_006 AVTAELLS--------H-------------FKEPKRRGIFRQIDSGSNLTTDLIVQRIIT 310 320 330 340 220 230 240 250 260 270 pF1KB6 DYDVYARRNLQRGYTAKELNVSFINEKKYHLQERVDKVKKKVKDVEEKSKEFVQKVEEKS . : :: .. :::: XP_006 NRLEYEARNQKK--EAKELAFLEAARQQAAQPLGERDGDF 350 360 370 380 >>NP_002852 (OMIM: 602679) ethanolamine-phosphate cytidy (389 aa) initn: 359 init1: 254 opt: 344 Z-score: 330.0 bits: 69.8 E(85289): 1.2e-11 Smith-Waterman score: 344; 40.8% identity (66.9% similar) in 142 aa overlap (70-210:16-154) 40 50 60 70 80 90 pF1KB6 GLRQPAPFSDEIEVDFSKPYVRVTMEEASRGTPCERPVRVYADGIFDLFHSGHARALMQA : .: :::. :: .:. : ::. : :: NP_002 MIRNGRGAAGGAEQPGPGGRRAVRVWCDGCYDMVHYGHSNQLRQA 10 20 30 40 100 110 120 130 140 150 pF1KB6 KNLFPNTYLIVGVCSDELTHNFKGFTVMNENERYDAVQHCRYVDEVVRNAPWTLTPEFLA . . . :::::: .:: . :: :....::: :: ..::::: ::.. : : : NP_002 RAM--GDYLIVGVHTDEEIAKHKGPPVFTQEERYKMVQAIKWVDEVVPAAPYVTTLETLD 50 60 70 80 90 100 160 170 180 190 200 210 pF1KB6 EHRIDFVAH-DDIPYSSAGSDDVYKHIKEAGMFAPTQRTEGISTSDIITRIVRDYDVYAR .. :: .: .:: . : : .:...:.:: . .::.:.::.:.. :.. NP_002 KYNCDFCVHGNDITLTVDGRD-TYEEVKQAGRYRECKRTQGVSTTDLVGRMLLVTKAHHS 110 120 130 140 150 160 220 230 240 250 260 270 pF1KB6 RNLQRGYTAKELNVSFINEKKYHLQERVDKVKKKVKDVEEKSKEFVQKVEEKSIDLIQKW NP_002 SQEMSSEYREYADSFGKCPGGRNPWTGVSQFLQTSQKIIQFASGKEPQPGETVIYVAGAF 170 180 190 200 210 220 >-- initn: 239 init1: 130 opt: 304 Z-score: 292.6 bits: 62.8 E(85289): 1.5e-09 Smith-Waterman score: 304; 34.5% identity (62.6% similar) in 171 aa overlap (64-230:201-368) 40 50 60 70 80 90 pF1KB6 VQRCAVGLRQPAPFSDEIEVDFSKPYVRVTMEEASRGTPCERPVRVYADGIFDLFHSGHA .. :: : . .:. : ::::: ::. NP_002 REYADSFGKCPGGRNPWTGVSQFLQTSQKIIQFASGKEPQPGETVIYVAGAFDLFHIGHV 180 190 200 210 220 230 100 110 120 130 140 150 pF1KB6 RALMQAKNLFPNTYLIVGVCSDELTHNFKG--FTVMNENERYDAVQHCRYVDEVVRNAPW : ... : :.:.:. :. ....:: . .:: .:: .: ::::.::: .::. NP_002 DFLEKVHRLAERPYIIAGLHFDQEVNHYKGKNYPIMNLHERTLSVLACRYVSEVVIGAPY 240 250 260 270 280 290 160 170 180 190 200 pF1KB6 TLTPEFLAEHRIDFVAHD--DIPYSSAGSDDVYKHIKEAGMFAPTQRTEGISTSDIITRI ..: :.:.. ..:.: : .: . ::: :.. :. :.: . ...:. :. :: NP_002 AVTAELLSHFKVDLVCHGKTEIIPDRDGSDP-YQEPKRRGIFRQIDSGSNLTTDLIVQRI 300 310 320 330 340 210 220 230 240 250 260 pF1KB6 VRDYDVYARRNLQRGYTAKELNVSFINEKKYHLQERVDKVKKKVKDVEEKSKEFVQKVEE . . : :: .. :::: NP_002 ITNRLEYEARNQKK--EAKELAFLEAARQQAAQPLGERDGDF 350 360 370 380 >>NP_001171846 (OMIM: 602679) ethanolamine-phosphate cyt (407 aa) initn: 337 init1: 254 opt: 344 Z-score: 329.7 bits: 69.8 E(85289): 1.3e-11 Smith-Waterman score: 344; 40.8% identity (66.9% similar) in 142 aa overlap (70-210:16-154) 40 50 60 70 80 90 pF1KB6 GLRQPAPFSDEIEVDFSKPYVRVTMEEASRGTPCERPVRVYADGIFDLFHSGHARALMQA : .: :::. :: .:. : ::. : :: NP_001 MIRNGRGAAGGAEQPGPGGRRAVRVWCDGCYDMVHYGHSNQLRQA 10 20 30 40 100 110 120 130 140 150 pF1KB6 KNLFPNTYLIVGVCSDELTHNFKGFTVMNENERYDAVQHCRYVDEVVRNAPWTLTPEFLA . . . :::::: .:: . :: :....::: :: ..::::: ::.. : : : NP_001 RAM--GDYLIVGVHTDEEIAKHKGPPVFTQEERYKMVQAIKWVDEVVPAAPYVTTLETLD 50 60 70 80 90 100 160 170 180 190 200 210 pF1KB6 EHRIDFVAH-DDIPYSSAGSDDVYKHIKEAGMFAPTQRTEGISTSDIITRIVRDYDVYAR .. :: .: .:: . : : .:...:.:: . .::.:.::.:.. :.. NP_001 KYNCDFCVHGNDITLTVDGRD-TYEEVKQAGRYRECKRTQGVSTTDLVGRMLLVTKAHHS 110 120 130 140 150 160 220 230 240 250 260 270 pF1KB6 RNLQRGYTAKELNVSFINEKKYHLQERVDKVKKKVKDVEEKSKEFVQKVEEKSIDLIQKW NP_001 SQEMSSEYREYADSFGKPPHPIPAGDILSSEGCSQCPGGRNPWTGVSQFLQTSQKIIQFA 170 180 190 200 210 220 >-- initn: 239 init1: 130 opt: 304 Z-score: 292.3 bits: 62.9 E(85289): 1.5e-09 Smith-Waterman score: 304; 34.5% identity (62.6% similar) in 171 aa overlap (64-230:219-386) 40 50 60 70 80 90 pF1KB6 VQRCAVGLRQPAPFSDEIEVDFSKPYVRVTMEEASRGTPCERPVRVYADGIFDLFHSGHA .. :: : . .:. : ::::: ::. NP_001 ILSSEGCSQCPGGRNPWTGVSQFLQTSQKIIQFASGKEPQPGETVIYVAGAFDLFHIGHV 190 200 210 220 230 240 100 110 120 130 140 150 pF1KB6 RALMQAKNLFPNTYLIVGVCSDELTHNFKG--FTVMNENERYDAVQHCRYVDEVVRNAPW : ... : :.:.:. :. ....:: . .:: .:: .: ::::.::: .::. NP_001 DFLEKVHRLAERPYIIAGLHFDQEVNHYKGKNYPIMNLHERTLSVLACRYVSEVVIGAPY 250 260 270 280 290 300 160 170 180 190 200 pF1KB6 TLTPEFLAEHRIDFVAHD--DIPYSSAGSDDVYKHIKEAGMFAPTQRTEGISTSDIITRI ..: :.:.. ..:.: : .: . ::: :.. :. :.: . ...:. :. :: NP_001 AVTAELLSHFKVDLVCHGKTEIIPDRDGSDP-YQEPKRRGIFRQIDSGSNLTTDLIVQRI 310 320 330 340 350 360 210 220 230 240 250 260 pF1KB6 VRDYDVYARRNLQRGYTAKELNVSFINEKKYHLQERVDKVKKKVKDVEEKSKEFVQKVEE . . : :: .. :::: NP_001 ITNRLEYEARNQKK--EAKELAFLEAARQQAAQPLGERDGDF 370 380 390 400 367 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 11:26:01 2016 done: Sat Nov 5 11:26:02 2016 Total Scan time: 6.930 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]