FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6538, 391 aa 1>>>pF1KB6538 391 - 391 aa - 391 aa Library: /omim/omim.rfq.tfa 64369986 residues in 92320 sequences Statistics: Expectation_n fit: rho(ln(x))= 8.7700+/-0.000317; mu= 2.1164+/- 0.020 mean_var=184.4819+/-37.190, 0's: 0 Z-trim(122.3): 27 B-trim: 820 in 1/50 Lambda= 0.094427 statistics sampled from 41877 (41904) to 41877 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.773), E-opt: 0.2 (0.454), width: 16 Scan time: 4.770 The best scores are: opt bits E(92320) NP_004575 (OMIM: 603761) cell cycle checkpoint con ( 391) 2618 368.4 1.7e-101 XP_006718715 (OMIM: 603761) cell cycle checkpoint ( 402) 2389 337.2 4.4e-92 NP_001230153 (OMIM: 603761) cell cycle checkpoint ( 315) 2113 299.6 7.5e-81 XP_016873586 (OMIM: 603761) cell cycle checkpoint ( 279) 1783 254.6 2.3e-67 XP_016873587 (OMIM: 603761) cell cycle checkpoint ( 199) 1354 196.1 6.8e-50 XP_024304628 (OMIM: 608368) cell cycle checkpoint ( 345) 533 84.4 5e-16 NP_001273461 (OMIM: 608368) cell cycle checkpoint ( 345) 533 84.4 5e-16 NP_001354980 (OMIM: 608368) cell cycle checkpoint ( 345) 533 84.4 5e-16 NP_001273460 (OMIM: 608368) cell cycle checkpoint ( 345) 533 84.4 5e-16 XP_024304629 (OMIM: 608368) cell cycle checkpoint ( 345) 533 84.4 5e-16 XP_011536274 (OMIM: 608368) cell cycle checkpoint ( 393) 533 84.4 5.6e-16 NP_001354982 (OMIM: 608368) cell cycle checkpoint ( 338) 503 80.3 8.4e-15 XP_016874366 (OMIM: 608368) cell cycle checkpoint ( 365) 495 79.2 1.9e-14 NP_001354981 (OMIM: 608368) cell cycle checkpoint ( 410) 464 75.0 3.9e-13 NP_001273464 (OMIM: 608368) cell cycle checkpoint ( 417) 464 75.0 4e-13 NP_689655 (OMIM: 608368) cell cycle checkpoint con ( 429) 464 75.0 4.1e-13 XP_016874371 (OMIM: 608368) cell cycle checkpoint ( 259) 313 54.3 4.2e-07 NP_001273462 (OMIM: 608368) cell cycle checkpoint ( 259) 313 54.3 4.2e-07 NP_001273463 (OMIM: 608368) cell cycle checkpoint ( 259) 313 54.3 4.2e-07 NP_001273465 (OMIM: 608368) cell cycle checkpoint ( 341) 278 49.6 1.4e-05 XP_005253906 (OMIM: 608368) cell cycle checkpoint ( 348) 278 49.6 1.5e-05 XP_016874369 (OMIM: 608368) cell cycle checkpoint ( 220) 265 47.7 3.4e-05 XP_016874368 (OMIM: 608368) cell cycle checkpoint ( 220) 265 47.7 3.4e-05 NP_001354983 (OMIM: 608368) cell cycle checkpoint ( 220) 265 47.7 3.4e-05 NP_001354984 (OMIM: 608368) cell cycle checkpoint ( 220) 265 47.7 3.4e-05 NP_001354985 (OMIM: 608368) cell cycle checkpoint ( 213) 235 43.6 0.00056 XP_016874370 (OMIM: 608368) cell cycle checkpoint ( 213) 235 43.6 0.00056 >>NP_004575 (OMIM: 603761) cell cycle checkpoint control (391 aa) initn: 2618 init1: 2618 opt: 2618 Z-score: 1943.6 bits: 368.4 E(92320): 1.7e-101 Smith-Waterman score: 2618; 100.0% identity (100.0% similar) in 391 aa overlap (1-391:1-391) 10 20 30 40 50 60 pF1KB6 MKCLVTGGNVKVLGKAVHSLSRIGDELYLEPLEDGLSLRTVNSSRSAYACFLFAPLFFQQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 MKCLVTGGNVKVLGKAVHSLSRIGDELYLEPLEDGLSLRTVNSSRSAYACFLFAPLFFQQ 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 YQAATPGQDLLRCKILMKSFLSVFRSLAMLEKTVEKCCISLNGRSSRLVVQLHCKFGVRK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 YQAATPGQDLLRCKILMKSFLSVFRSLAMLEKTVEKCCISLNGRSSRLVVQLHCKFGVRK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 THNLSFQDCESLQAVFDPASCPHMLRAPARVLGEAVLPFSPALAEVTLGIGRGRRVILRS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 THNLSFQDCESLQAVFDPASCPHMLRAPARVLGEAVLPFSPALAEVTLGIGRGRRVILRS 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 YHEEEADSTAKAMVTEMCLGEEDFQQLQAQEGVAITFCLKEFRGLLSFAESANLNLSIHF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 YHEEEADSTAKAMVTEMCLGEEDFQQLQAQEGVAITFCLKEFRGLLSFAESANLNLSIHF 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 DAPGRPAIFTIKDSLLDGHFVLATLSDTDSHSQDLGSPERHQPVPQLQAHSTPHPDDFAN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 DAPGRPAIFTIKDSLLDGHFVLATLSDTDSHSQDLGSPERHQPVPQLQAHSTPHPDDFAN 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 DDIDSYMIAMETTIGNEGSRVLPSISLSPGPQPPKSPGPHSEEEDEAEPSTVPGTPPPKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_004 DDIDSYMIAMETTIGNEGSRVLPSISLSPGPQPPKSPGPHSEEEDEAEPSTVPGTPPPKK 310 320 330 340 350 360 370 380 390 pF1KB6 FRSLFFGSILAPVRSPQGPSPVLAEDSEGEG ::::::::::::::::::::::::::::::: NP_004 FRSLFFGSILAPVRSPQGPSPVLAEDSEGEG 370 380 390 >>XP_006718715 (OMIM: 603761) cell cycle checkpoint cont (402 aa) initn: 2389 init1: 2389 opt: 2389 Z-score: 1774.8 bits: 337.2 E(92320): 4.4e-92 Smith-Waterman score: 2389; 100.0% identity (100.0% similar) in 356 aa overlap (36-391:47-402) 10 20 30 40 50 60 pF1KB6 TGGNVKVLGKAVHSLSRIGDELYLEPLEDGLSLRTVNSSRSAYACFLFAPLFFQQYQAAT :::::::::::::::::::::::::::::: XP_006 IGQVCEQKQPEGWVCGCPLTTSLSLLFVAQLSLRTVNSSRSAYACFLFAPLFFQQYQAAT 20 30 40 50 60 70 70 80 90 100 110 120 pF1KB6 PGQDLLRCKILMKSFLSVFRSLAMLEKTVEKCCISLNGRSSRLVVQLHCKFGVRKTHNLS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PGQDLLRCKILMKSFLSVFRSLAMLEKTVEKCCISLNGRSSRLVVQLHCKFGVRKTHNLS 80 90 100 110 120 130 130 140 150 160 170 180 pF1KB6 FQDCESLQAVFDPASCPHMLRAPARVLGEAVLPFSPALAEVTLGIGRGRRVILRSYHEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 FQDCESLQAVFDPASCPHMLRAPARVLGEAVLPFSPALAEVTLGIGRGRRVILRSYHEEE 140 150 160 170 180 190 190 200 210 220 230 240 pF1KB6 ADSTAKAMVTEMCLGEEDFQQLQAQEGVAITFCLKEFRGLLSFAESANLNLSIHFDAPGR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ADSTAKAMVTEMCLGEEDFQQLQAQEGVAITFCLKEFRGLLSFAESANLNLSIHFDAPGR 200 210 220 230 240 250 250 260 270 280 290 300 pF1KB6 PAIFTIKDSLLDGHFVLATLSDTDSHSQDLGSPERHQPVPQLQAHSTPHPDDFANDDIDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 PAIFTIKDSLLDGHFVLATLSDTDSHSQDLGSPERHQPVPQLQAHSTPHPDDFANDDIDS 260 270 280 290 300 310 310 320 330 340 350 360 pF1KB6 YMIAMETTIGNEGSRVLPSISLSPGPQPPKSPGPHSEEEDEAEPSTVPGTPPPKKFRSLF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 YMIAMETTIGNEGSRVLPSISLSPGPQPPKSPGPHSEEEDEAEPSTVPGTPPPKKFRSLF 320 330 340 350 360 370 370 380 390 pF1KB6 FGSILAPVRSPQGPSPVLAEDSEGEG :::::::::::::::::::::::::: XP_006 FGSILAPVRSPQGPSPVLAEDSEGEG 380 390 400 >>NP_001230153 (OMIM: 603761) cell cycle checkpoint cont (315 aa) initn: 2113 init1: 2113 opt: 2113 Z-score: 1573.1 bits: 299.6 E(92320): 7.5e-81 Smith-Waterman score: 2113; 99.7% identity (100.0% similar) in 315 aa overlap (77-391:1-315) 50 60 70 80 90 100 pF1KB6 AYACFLFAPLFFQQYQAATPGQDLLRCKILMKSFLSVFRSLAMLEKTVEKCCISLNGRSS :.:::::::::::::::::::::::::::: NP_001 MQSFLSVFRSLAMLEKTVEKCCISLNGRSS 10 20 30 110 120 130 140 150 160 pF1KB6 RLVVQLHCKFGVRKTHNLSFQDCESLQAVFDPASCPHMLRAPARVLGEAVLPFSPALAEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 RLVVQLHCKFGVRKTHNLSFQDCESLQAVFDPASCPHMLRAPARVLGEAVLPFSPALAEV 40 50 60 70 80 90 170 180 190 200 210 220 pF1KB6 TLGIGRGRRVILRSYHEEEADSTAKAMVTEMCLGEEDFQQLQAQEGVAITFCLKEFRGLL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TLGIGRGRRVILRSYHEEEADSTAKAMVTEMCLGEEDFQQLQAQEGVAITFCLKEFRGLL 100 110 120 130 140 150 230 240 250 260 270 280 pF1KB6 SFAESANLNLSIHFDAPGRPAIFTIKDSLLDGHFVLATLSDTDSHSQDLGSPERHQPVPQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SFAESANLNLSIHFDAPGRPAIFTIKDSLLDGHFVLATLSDTDSHSQDLGSPERHQPVPQ 160 170 180 190 200 210 290 300 310 320 330 340 pF1KB6 LQAHSTPHPDDFANDDIDSYMIAMETTIGNEGSRVLPSISLSPGPQPPKSPGPHSEEEDE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LQAHSTPHPDDFANDDIDSYMIAMETTIGNEGSRVLPSISLSPGPQPPKSPGPHSEEEDE 220 230 240 250 260 270 350 360 370 380 390 pF1KB6 AEPSTVPGTPPPKKFRSLFFGSILAPVRSPQGPSPVLAEDSEGEG ::::::::::::::::::::::::::::::::::::::::::::: NP_001 AEPSTVPGTPPPKKFRSLFFGSILAPVRSPQGPSPVLAEDSEGEG 280 290 300 310 >>XP_016873586 (OMIM: 603761) cell cycle checkpoint cont (279 aa) initn: 1783 init1: 1783 opt: 1783 Z-score: 1331.0 bits: 254.6 E(92320): 2.3e-67 Smith-Waterman score: 1783; 100.0% identity (100.0% similar) in 264 aa overlap (128-391:16-279) 100 110 120 130 140 150 pF1KB6 CISLNGRSSRLVVQLHCKFGVRKTHNLSFQDCESLQAVFDPASCPHMLRAPARVLGEAVL :::::::::::::::::::::::::::::: XP_016 MAGAAAWWSSCIASSDCESLQAVFDPASCPHMLRAPARVLGEAVL 10 20 30 40 160 170 180 190 200 210 pF1KB6 PFSPALAEVTLGIGRGRRVILRSYHEEEADSTAKAMVTEMCLGEEDFQQLQAQEGVAITF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PFSPALAEVTLGIGRGRRVILRSYHEEEADSTAKAMVTEMCLGEEDFQQLQAQEGVAITF 50 60 70 80 90 100 220 230 240 250 260 270 pF1KB6 CLKEFRGLLSFAESANLNLSIHFDAPGRPAIFTIKDSLLDGHFVLATLSDTDSHSQDLGS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CLKEFRGLLSFAESANLNLSIHFDAPGRPAIFTIKDSLLDGHFVLATLSDTDSHSQDLGS 110 120 130 140 150 160 280 290 300 310 320 330 pF1KB6 PERHQPVPQLQAHSTPHPDDFANDDIDSYMIAMETTIGNEGSRVLPSISLSPGPQPPKSP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PERHQPVPQLQAHSTPHPDDFANDDIDSYMIAMETTIGNEGSRVLPSISLSPGPQPPKSP 170 180 190 200 210 220 340 350 360 370 380 390 pF1KB6 GPHSEEEDEAEPSTVPGTPPPKKFRSLFFGSILAPVRSPQGPSPVLAEDSEGEG :::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GPHSEEEDEAEPSTVPGTPPPKKFRSLFFGSILAPVRSPQGPSPVLAEDSEGEG 230 240 250 260 270 >>XP_016873587 (OMIM: 603761) cell cycle checkpoint cont (199 aa) initn: 1354 init1: 1354 opt: 1354 Z-score: 1017.3 bits: 196.1 E(92320): 6.8e-50 Smith-Waterman score: 1354; 100.0% identity (100.0% similar) in 199 aa overlap (193-391:1-199) 170 180 190 200 210 220 pF1KB6 LAEVTLGIGRGRRVILRSYHEEEADSTAKAMVTEMCLGEEDFQQLQAQEGVAITFCLKEF :::::::::::::::::::::::::::::: XP_016 MVTEMCLGEEDFQQLQAQEGVAITFCLKEF 10 20 30 230 240 250 260 270 280 pF1KB6 RGLLSFAESANLNLSIHFDAPGRPAIFTIKDSLLDGHFVLATLSDTDSHSQDLGSPERHQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 RGLLSFAESANLNLSIHFDAPGRPAIFTIKDSLLDGHFVLATLSDTDSHSQDLGSPERHQ 40 50 60 70 80 90 290 300 310 320 330 340 pF1KB6 PVPQLQAHSTPHPDDFANDDIDSYMIAMETTIGNEGSRVLPSISLSPGPQPPKSPGPHSE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PVPQLQAHSTPHPDDFANDDIDSYMIAMETTIGNEGSRVLPSISLSPGPQPPKSPGPHSE 100 110 120 130 140 150 350 360 370 380 390 pF1KB6 EEDEAEPSTVPGTPPPKKFRSLFFGSILAPVRSPQGPSPVLAEDSEGEG ::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EEDEAEPSTVPGTPPPKKFRSLFFGSILAPVRSPQGPSPVLAEDSEGEG 160 170 180 190 >>XP_024304628 (OMIM: 608368) cell cycle checkpoint cont (345 aa) initn: 321 init1: 275 opt: 533 Z-score: 409.3 bits: 84.4 E(92320): 5e-16 Smith-Waterman score: 533; 31.0% identity (61.3% similar) in 326 aa overlap (71-390:12-334) 50 60 70 80 90 100 pF1KB6 VNSSRSAYACFLFAPLFFQQYQAATPGQDLLRCKILMKSFLSVFRSLAMLEKTVEKCCIS :.::. :::.: .:: : ::...::: : XP_024 MSENELDTTLHLKCKLGMKSILPIFRCLNSLERNIEKCRIF 10 20 30 40 110 120 130 140 150 160 pF1KB6 LNGRSSRLVVQLHCKFGVRKTHNLSFQDCESLQAVFDPASCPHMLRAPARVLGEAVLPFS . . ..:.:. . :...:::. ::. . ::..:: : . : :.:..:.. :. XP_024 TRSDKCKVVIQFFYRHGIKRTHNICFQESQPLQVIFDKNVCTNTLMIQPRLLADAIVLFT 50 60 70 80 90 100 170 180 190 200 210 220 pF1KB6 PALAEVTLGIGRGRRVILRSYHEEEADSTAKAMVTEMCLGEEDFQQLQAQEGVAITFCLK . ::::.. :.: .:: : ..:. .:: .: ..:. .: . ::::.: XP_024 SSQEEVTLAV-TPLNFCLKSSNEESMD-LSNAVHSEMFVGSDEFDFFQIGMDTEITFCFK 110 120 130 140 150 230 240 250 260 270 pF1KB6 EFRGLLSFAESANLNLSIHFDAPGRPAIFTIKDSLLDGHFVLATLSDTDSHS---QDLGS :..:.:.:.:... .::.:: ::.: ..: : :....:.::::.: .:.. :.: XP_024 ELKGILTFSEATHAPISIYFDFPGKPLALSIDDMLVEANFILATLADEQSRASSPQSLCL 160 170 180 190 200 210 280 290 300 310 320 330 pF1KB6 PERHQPVPQLQAHSTPHPDDFANDDIDSYMIAMETTIGNEGSRVLPSISLSPGPQPPKSP .... .. .. . : . : : : . .: . .. .: . XP_024 SQKRKRSDLIEKKAGKNVTGQALECI-SKKAAPRRLYPKETLTNISALENCGSPAMKRVD 220 230 240 250 260 270 340 350 360 370 380 390 pF1KB6 GPHSEEEDEAEPST--VPGTPPPKKFRSLFFGSILAPVRSP-QGPSPVLAEDSEGEG : :: . . .: :::. .:: .:::.. . . . : ::. :..: XP_024 GDVSEVSESSVSNTEEVPGSLCLRKFSCMFFGAVSSDQQEHFNHPFDSLARASDSEEDMN 280 290 300 310 320 330 XP_024 NGSFSIF 340 >>NP_001273461 (OMIM: 608368) cell cycle checkpoint cont (345 aa) initn: 321 init1: 275 opt: 533 Z-score: 409.3 bits: 84.4 E(92320): 5e-16 Smith-Waterman score: 533; 31.0% identity (61.3% similar) in 326 aa overlap (71-390:12-334) 50 60 70 80 90 100 pF1KB6 VNSSRSAYACFLFAPLFFQQYQAATPGQDLLRCKILMKSFLSVFRSLAMLEKTVEKCCIS :.::. :::.: .:: : ::...::: : NP_001 MSENELDTTLHLKCKLGMKSILPIFRCLNSLERNIEKCRIF 10 20 30 40 110 120 130 140 150 160 pF1KB6 LNGRSSRLVVQLHCKFGVRKTHNLSFQDCESLQAVFDPASCPHMLRAPARVLGEAVLPFS . . ..:.:. . :...:::. ::. . ::..:: : . : :.:..:.. :. NP_001 TRSDKCKVVIQFFYRHGIKRTHNICFQESQPLQVIFDKNVCTNTLMIQPRLLADAIVLFT 50 60 70 80 90 100 170 180 190 200 210 220 pF1KB6 PALAEVTLGIGRGRRVILRSYHEEEADSTAKAMVTEMCLGEEDFQQLQAQEGVAITFCLK . ::::.. :.: .:: : ..:. .:: .: ..:. .: . ::::.: NP_001 SSQEEVTLAV-TPLNFCLKSSNEESMD-LSNAVHSEMFVGSDEFDFFQIGMDTEITFCFK 110 120 130 140 150 230 240 250 260 270 pF1KB6 EFRGLLSFAESANLNLSIHFDAPGRPAIFTIKDSLLDGHFVLATLSDTDSHS---QDLGS :..:.:.:.:... .::.:: ::.: ..: : :....:.::::.: .:.. :.: NP_001 ELKGILTFSEATHAPISIYFDFPGKPLALSIDDMLVEANFILATLADEQSRASSPQSLCL 160 170 180 190 200 210 280 290 300 310 320 330 pF1KB6 PERHQPVPQLQAHSTPHPDDFANDDIDSYMIAMETTIGNEGSRVLPSISLSPGPQPPKSP .... .. .. . : . : : : . .: . .. .: . NP_001 SQKRKRSDLIEKKAGKNVTGQALECI-SKKAAPRRLYPKETLTNISALENCGSPAMKRVD 220 230 240 250 260 270 340 350 360 370 380 390 pF1KB6 GPHSEEEDEAEPST--VPGTPPPKKFRSLFFGSILAPVRSP-QGPSPVLAEDSEGEG : :: . . .: :::. .:: .:::.. . . . : ::. :..: NP_001 GDVSEVSESSVSNTEEVPGSLCLRKFSCMFFGAVSSDQQEHFNHPFDSLARASDSEEDMN 280 290 300 310 320 330 NP_001 NGSFSIF 340 >>NP_001354980 (OMIM: 608368) cell cycle checkpoint cont (345 aa) initn: 321 init1: 275 opt: 533 Z-score: 409.3 bits: 84.4 E(92320): 5e-16 Smith-Waterman score: 533; 31.0% identity (61.3% similar) in 326 aa overlap (71-390:12-334) 50 60 70 80 90 100 pF1KB6 VNSSRSAYACFLFAPLFFQQYQAATPGQDLLRCKILMKSFLSVFRSLAMLEKTVEKCCIS :.::. :::.: .:: : ::...::: : NP_001 MSENELDTTLHLKCKLGMKSILPIFRCLNSLERNIEKCRIF 10 20 30 40 110 120 130 140 150 160 pF1KB6 LNGRSSRLVVQLHCKFGVRKTHNLSFQDCESLQAVFDPASCPHMLRAPARVLGEAVLPFS . . ..:.:. . :...:::. ::. . ::..:: : . : :.:..:.. :. NP_001 TRSDKCKVVIQFFYRHGIKRTHNICFQESQPLQVIFDKNVCTNTLMIQPRLLADAIVLFT 50 60 70 80 90 100 170 180 190 200 210 220 pF1KB6 PALAEVTLGIGRGRRVILRSYHEEEADSTAKAMVTEMCLGEEDFQQLQAQEGVAITFCLK . ::::.. :.: .:: : ..:. .:: .: ..:. .: . ::::.: NP_001 SSQEEVTLAV-TPLNFCLKSSNEESMD-LSNAVHSEMFVGSDEFDFFQIGMDTEITFCFK 110 120 130 140 150 230 240 250 260 270 pF1KB6 EFRGLLSFAESANLNLSIHFDAPGRPAIFTIKDSLLDGHFVLATLSDTDSHS---QDLGS :..:.:.:.:... .::.:: ::.: ..: : :....:.::::.: .:.. :.: NP_001 ELKGILTFSEATHAPISIYFDFPGKPLALSIDDMLVEANFILATLADEQSRASSPQSLCL 160 170 180 190 200 210 280 290 300 310 320 330 pF1KB6 PERHQPVPQLQAHSTPHPDDFANDDIDSYMIAMETTIGNEGSRVLPSISLSPGPQPPKSP .... .. .. . : . : : : . .: . .. .: . NP_001 SQKRKRSDLIEKKAGKNVTGQALECI-SKKAAPRRLYPKETLTNISALENCGSPAMKRVD 220 230 240 250 260 270 340 350 360 370 380 390 pF1KB6 GPHSEEEDEAEPST--VPGTPPPKKFRSLFFGSILAPVRSP-QGPSPVLAEDSEGEG : :: . . .: :::. .:: .:::.. . . . : ::. :..: NP_001 GDVSEVSESSVSNTEEVPGSLCLRKFSCMFFGAVSSDQQEHFNHPFDSLARASDSEEDMN 280 290 300 310 320 330 NP_001 NGSFSIF 340 >>NP_001273460 (OMIM: 608368) cell cycle checkpoint cont (345 aa) initn: 321 init1: 275 opt: 533 Z-score: 409.3 bits: 84.4 E(92320): 5e-16 Smith-Waterman score: 533; 31.0% identity (61.3% similar) in 326 aa overlap (71-390:12-334) 50 60 70 80 90 100 pF1KB6 VNSSRSAYACFLFAPLFFQQYQAATPGQDLLRCKILMKSFLSVFRSLAMLEKTVEKCCIS :.::. :::.: .:: : ::...::: : NP_001 MSENELDTTLHLKCKLGMKSILPIFRCLNSLERNIEKCRIF 10 20 30 40 110 120 130 140 150 160 pF1KB6 LNGRSSRLVVQLHCKFGVRKTHNLSFQDCESLQAVFDPASCPHMLRAPARVLGEAVLPFS . . ..:.:. . :...:::. ::. . ::..:: : . : :.:..:.. :. NP_001 TRSDKCKVVIQFFYRHGIKRTHNICFQESQPLQVIFDKNVCTNTLMIQPRLLADAIVLFT 50 60 70 80 90 100 170 180 190 200 210 220 pF1KB6 PALAEVTLGIGRGRRVILRSYHEEEADSTAKAMVTEMCLGEEDFQQLQAQEGVAITFCLK . ::::.. :.: .:: : ..:. .:: .: ..:. .: . ::::.: NP_001 SSQEEVTLAV-TPLNFCLKSSNEESMD-LSNAVHSEMFVGSDEFDFFQIGMDTEITFCFK 110 120 130 140 150 230 240 250 260 270 pF1KB6 EFRGLLSFAESANLNLSIHFDAPGRPAIFTIKDSLLDGHFVLATLSDTDSHS---QDLGS :..:.:.:.:... .::.:: ::.: ..: : :....:.::::.: .:.. :.: NP_001 ELKGILTFSEATHAPISIYFDFPGKPLALSIDDMLVEANFILATLADEQSRASSPQSLCL 160 170 180 190 200 210 280 290 300 310 320 330 pF1KB6 PERHQPVPQLQAHSTPHPDDFANDDIDSYMIAMETTIGNEGSRVLPSISLSPGPQPPKSP .... .. .. . : . : : : . .: . .. .: . NP_001 SQKRKRSDLIEKKAGKNVTGQALECI-SKKAAPRRLYPKETLTNISALENCGSPAMKRVD 220 230 240 250 260 270 340 350 360 370 380 390 pF1KB6 GPHSEEEDEAEPST--VPGTPPPKKFRSLFFGSILAPVRSP-QGPSPVLAEDSEGEG : :: . . .: :::. .:: .:::.. . . . : ::. :..: NP_001 GDVSEVSESSVSNTEEVPGSLCLRKFSCMFFGAVSSDQQEHFNHPFDSLARASDSEEDMN 280 290 300 310 320 330 NP_001 NGSFSIF 340 >>XP_024304629 (OMIM: 608368) cell cycle checkpoint cont (345 aa) initn: 321 init1: 275 opt: 533 Z-score: 409.3 bits: 84.4 E(92320): 5e-16 Smith-Waterman score: 533; 31.0% identity (61.3% similar) in 326 aa overlap (71-390:12-334) 50 60 70 80 90 100 pF1KB6 VNSSRSAYACFLFAPLFFQQYQAATPGQDLLRCKILMKSFLSVFRSLAMLEKTVEKCCIS :.::. :::.: .:: : ::...::: : XP_024 MSENELDTTLHLKCKLGMKSILPIFRCLNSLERNIEKCRIF 10 20 30 40 110 120 130 140 150 160 pF1KB6 LNGRSSRLVVQLHCKFGVRKTHNLSFQDCESLQAVFDPASCPHMLRAPARVLGEAVLPFS . . ..:.:. . :...:::. ::. . ::..:: : . : :.:..:.. :. XP_024 TRSDKCKVVIQFFYRHGIKRTHNICFQESQPLQVIFDKNVCTNTLMIQPRLLADAIVLFT 50 60 70 80 90 100 170 180 190 200 210 220 pF1KB6 PALAEVTLGIGRGRRVILRSYHEEEADSTAKAMVTEMCLGEEDFQQLQAQEGVAITFCLK . ::::.. :.: .:: : ..:. .:: .: ..:. .: . ::::.: XP_024 SSQEEVTLAV-TPLNFCLKSSNEESMD-LSNAVHSEMFVGSDEFDFFQIGMDTEITFCFK 110 120 130 140 150 230 240 250 260 270 pF1KB6 EFRGLLSFAESANLNLSIHFDAPGRPAIFTIKDSLLDGHFVLATLSDTDSHS---QDLGS :..:.:.:.:... .::.:: ::.: ..: : :....:.::::.: .:.. :.: XP_024 ELKGILTFSEATHAPISIYFDFPGKPLALSIDDMLVEANFILATLADEQSRASSPQSLCL 160 170 180 190 200 210 280 290 300 310 320 330 pF1KB6 PERHQPVPQLQAHSTPHPDDFANDDIDSYMIAMETTIGNEGSRVLPSISLSPGPQPPKSP .... .. .. . : . : : : . .: . .. .: . XP_024 SQKRKRSDLIEKKAGKNVTGQALECI-SKKAAPRRLYPKETLTNISALENCGSPAMKRVD 220 230 240 250 260 270 340 350 360 370 380 390 pF1KB6 GPHSEEEDEAEPST--VPGTPPPKKFRSLFFGSILAPVRSP-QGPSPVLAEDSEGEG : :: . . .: :::. .:: .:::.. . . . : ::. :..: XP_024 GDVSEVSESSVSNTEEVPGSLCLRKFSCMFFGAVSSDQQEHFNHPFDSLARASDSEEDMN 280 290 300 310 320 330 XP_024 NGSFSIF 340 391 residues in 1 query sequences 64369986 residues in 92320 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Thu Oct 24 21:33:43 2019 done: Thu Oct 24 21:33:44 2019 Total Scan time: 4.770 Total Display time: 0.050 Function used was FASTA [36.3.4 Apr, 2011]