FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6539, 368 aa 1>>>pF1KB6539 368 - 368 aa - 368 aa Library: human.CCDS.faa 18511270 residues in 32554 sequences Statistics: Expectation_n fit: rho(ln(x))= 6.1107+/-0.000983; mu= 12.1487+/- 0.058 mean_var=92.1868+/-18.781, 0's: 0 Z-trim(106.7): 85 B-trim: 156 in 1/49 Lambda= 0.133580 statistics sampled from 9034 (9127) to 9034 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.651), E-opt: 0.2 (0.28), width: 16 Scan time: 2.460 The best scores are: opt bits E(32554) CCDS63540.1 SEC13 gene_id:6396|Hs108|chr3 ( 368) 2591 509.7 1.6e-144 CCDS2599.1 SEC13 gene_id:6396|Hs108|chr3 ( 322) 2267 447.3 8.8e-126 CCDS46751.1 SEC13 gene_id:6396|Hs108|chr3 ( 308) 2181 430.7 8.3e-121 CCDS45832.1 SEH1L gene_id:81929|Hs108|chr18 ( 360) 346 77.1 2.7e-14 CCDS32791.1 SEH1L gene_id:81929|Hs108|chr18 ( 421) 346 77.1 3e-14 >>CCDS63540.1 SEC13 gene_id:6396|Hs108|chr3 (368 aa) initn: 2591 init1: 2591 opt: 2591 Z-score: 2708.2 bits: 509.7 E(32554): 1.6e-144 Smith-Waterman score: 2591; 100.0% identity (100.0% similar) in 368 aa overlap (1-368:1-368) 10 20 30 40 50 60 pF1KB6 MREPVLTWCVPLELLCSHPLPLSAFLKSQVKLYTYRACAGKDEMGKMVSVINTVDTSHED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 MREPVLTWCVPLELLCSHPLPLSAFLKSQVKLYTYRACAGKDEMGKMVSVINTVDTSHED 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 MIHDAQMDYYGTRLATCSSDRSVKIFDVRNGGQILIADLRGHEGPVWQVAWAHPMYGNIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 MIHDAQMDYYGTRLATCSSDRSVKIFDVRNGGQILIADLRGHEGPVWQVAWAHPMYGNIL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 ASCSYDRKVIIWREENGTWEKSHEHAGHDSSVNSVCWAPHDYGLILACGSSDGAISLLTY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 ASCSYDRKVIIWREENGTWEKSHEHAGHDSSVNSVCWAPHDYGLILACGSSDGAISLLTY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 TGEGQWEVKKINNAHTIGCNAVSWAPAVVPGSLIDHPSGQKPNYIKRFASGGCDNLIKLW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 TGEGQWEVKKINNAHTIGCNAVSWAPAVVPGSLIDHPSGQKPNYIKRFASGGCDNLIKLW 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 KEEEDGQWKEEQKLEAHSDWVRDVAWAPSIGLPTSTIASCSQDGRVFIWTCDDASSNTWS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 KEEEDGQWKEEQKLEAHSDWVRDVAWAPSIGLPTSTIASCSQDGRVFIWTCDDASSNTWS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 PKLLHKFNDVVWHVSWSITANILAVSGGDNKVTLWKESVDGQWVCISDVNKGQGSVSASV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS63 PKLLHKFNDVVWHVSWSITANILAVSGGDNKVTLWKESVDGQWVCISDVNKGQGSVSASV 310 320 330 340 350 360 pF1KB6 TEGQQNEQ :::::::: CCDS63 TEGQQNEQ >>CCDS2599.1 SEC13 gene_id:6396|Hs108|chr3 (322 aa) initn: 2267 init1: 2267 opt: 2267 Z-score: 2371.6 bits: 447.3 E(32554): 8.8e-126 Smith-Waterman score: 2267; 100.0% identity (100.0% similar) in 322 aa overlap (47-368:1-322) 20 30 40 50 60 70 pF1KB6 SHPLPLSAFLKSQVKLYTYRACAGKDEMGKMVSVINTVDTSHEDMIHDAQMDYYGTRLAT :::::::::::::::::::::::::::::: CCDS25 MVSVINTVDTSHEDMIHDAQMDYYGTRLAT 10 20 30 80 90 100 110 120 130 pF1KB6 CSSDRSVKIFDVRNGGQILIADLRGHEGPVWQVAWAHPMYGNILASCSYDRKVIIWREEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS25 CSSDRSVKIFDVRNGGQILIADLRGHEGPVWQVAWAHPMYGNILASCSYDRKVIIWREEN 40 50 60 70 80 90 140 150 160 170 180 190 pF1KB6 GTWEKSHEHAGHDSSVNSVCWAPHDYGLILACGSSDGAISLLTYTGEGQWEVKKINNAHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS25 GTWEKSHEHAGHDSSVNSVCWAPHDYGLILACGSSDGAISLLTYTGEGQWEVKKINNAHT 100 110 120 130 140 150 200 210 220 230 240 250 pF1KB6 IGCNAVSWAPAVVPGSLIDHPSGQKPNYIKRFASGGCDNLIKLWKEEEDGQWKEEQKLEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS25 IGCNAVSWAPAVVPGSLIDHPSGQKPNYIKRFASGGCDNLIKLWKEEEDGQWKEEQKLEA 160 170 180 190 200 210 260 270 280 290 300 310 pF1KB6 HSDWVRDVAWAPSIGLPTSTIASCSQDGRVFIWTCDDASSNTWSPKLLHKFNDVVWHVSW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS25 HSDWVRDVAWAPSIGLPTSTIASCSQDGRVFIWTCDDASSNTWSPKLLHKFNDVVWHVSW 220 230 240 250 260 270 320 330 340 350 360 pF1KB6 SITANILAVSGGDNKVTLWKESVDGQWVCISDVNKGQGSVSASVTEGQQNEQ :::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS25 SITANILAVSGGDNKVTLWKESVDGQWVCISDVNKGQGSVSASVTEGQQNEQ 280 290 300 310 320 >>CCDS46751.1 SEC13 gene_id:6396|Hs108|chr3 (308 aa) initn: 2181 init1: 2181 opt: 2181 Z-score: 2282.3 bits: 430.7 E(32554): 8.3e-121 Smith-Waterman score: 2181; 100.0% identity (100.0% similar) in 308 aa overlap (61-368:1-308) 40 50 60 70 80 90 pF1KB6 KLYTYRACAGKDEMGKMVSVINTVDTSHEDMIHDAQMDYYGTRLATCSSDRSVKIFDVRN :::::::::::::::::::::::::::::: CCDS46 MIHDAQMDYYGTRLATCSSDRSVKIFDVRN 10 20 30 100 110 120 130 140 150 pF1KB6 GGQILIADLRGHEGPVWQVAWAHPMYGNILASCSYDRKVIIWREENGTWEKSHEHAGHDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 GGQILIADLRGHEGPVWQVAWAHPMYGNILASCSYDRKVIIWREENGTWEKSHEHAGHDS 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB6 SVNSVCWAPHDYGLILACGSSDGAISLLTYTGEGQWEVKKINNAHTIGCNAVSWAPAVVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 SVNSVCWAPHDYGLILACGSSDGAISLLTYTGEGQWEVKKINNAHTIGCNAVSWAPAVVP 100 110 120 130 140 150 220 230 240 250 260 270 pF1KB6 GSLIDHPSGQKPNYIKRFASGGCDNLIKLWKEEEDGQWKEEQKLEAHSDWVRDVAWAPSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 GSLIDHPSGQKPNYIKRFASGGCDNLIKLWKEEEDGQWKEEQKLEAHSDWVRDVAWAPSI 160 170 180 190 200 210 280 290 300 310 320 330 pF1KB6 GLPTSTIASCSQDGRVFIWTCDDASSNTWSPKLLHKFNDVVWHVSWSITANILAVSGGDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: CCDS46 GLPTSTIASCSQDGRVFIWTCDDASSNTWSPKLLHKFNDVVWHVSWSITANILAVSGGDN 220 230 240 250 260 270 340 350 360 pF1KB6 KVTLWKESVDGQWVCISDVNKGQGSVSASVTEGQQNEQ :::::::::::::::::::::::::::::::::::::: CCDS46 KVTLWKESVDGQWVCISDVNKGQGSVSASVTEGQQNEQ 280 290 300 >>CCDS45832.1 SEH1L gene_id:81929|Hs108|chr18 (360 aa) initn: 493 init1: 158 opt: 346 Z-score: 370.2 bits: 77.1 E(32554): 2.7e-14 Smith-Waterman score: 577; 31.0% identity (61.7% similar) in 345 aa overlap (50-366:3-336) 20 30 40 50 60 70 pF1KB6 LPLSAFLKSQVKLYTYRACAGKDEMGKMVSVINTVDTSHEDMIHDAQMDYYGTRLATCSS : .. ..:.:.:::...:..: :.::::: CCDS45 MFVARSIAADHKDLIHDVSFDFHGRRMATCSS 10 20 30 80 90 100 110 120 130 pF1KB6 DRSVKIFDVRNGGQI-LIADLRGHEGPVWQVAWAHPMYGNILASCSYDRKVIIWREENGT :.:::..: ..:. :. . : : ::.:.:::: .:..:::::.:: . .:.: : CCDS45 DQSVKVWDKSESGDWHCTASWKTHSGSVWRVTWAHPEFGQVLASCSFDRTAAVWEEIVGE 40 50 60 70 80 90 140 150 160 170 180 pF1KB6 ----------WEKSHEHAGHDSSVNSVCWAPHDYGLILACGSSDGAISLLT---YTGEGQ : : . .::..: .::. .::.:: :.:: . . . .: CCDS45 SNDKLRGQSHWVKRTTLVDSRTSVTDVKFAPKHMGLMLATCSADGIVRIYEAPDVMNLSQ 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB6 WEVKKINNAHTIGCNAVSWAPAV--VPGSLIDHPSGQK-PNYIKRFASGGCDNLIKLWKE : ... . . ..:. .:: :. . . .: : .. :: . . ..... CCDS45 WSLQH-EISCKLSCSCISWNPSSSRAHSPMIAVGSDDSSPNAMAK---------VQIFEY 160 170 180 190 200 250 260 270 280 290 300 pF1KB6 EEDG-QWKEEQKLEAHSDWVRDVAWAPSIGLPTSTIASCSQDGRVF-IWTCDDASSNTWS .:. .. . . : . .: :.:.:.::..: .: ..: :.: . ... . CCDS45 NENTRKYAKAETLMTVTDPVHDIAFAPNLGRSFHILAIATKDVRIFTLKPVRKELTSSGG 210 220 230 240 250 260 310 320 330 340 350 pF1KB6 P-----KLLHKF---NDVVWHVSWSITANILAVSGGDNKVTLWKESVDGQWVCISDVNKG : ... .: :. ::.:::.::...:: :: :. : ::: . .: : . . :: CCDS45 PTKFEIHIVAQFDNHNSQVWRVSWNITGTVLASSGDDGCVRLWKANYMDNWKC-TGILKG 270 280 290 300 310 320 360 pF1KB6 QGS-VSASVTEGQQNEQ .:: :..: .: .: CCDS45 NGSPVNGSSQQGTSNPSLGSTIPSLQNSLNGSSAGRKHS 330 340 350 360 >>CCDS32791.1 SEH1L gene_id:81929|Hs108|chr18 (421 aa) initn: 493 init1: 158 opt: 346 Z-score: 369.2 bits: 77.1 E(32554): 3e-14 Smith-Waterman score: 577; 31.0% identity (61.7% similar) in 345 aa overlap (50-366:3-336) 20 30 40 50 60 70 pF1KB6 LPLSAFLKSQVKLYTYRACAGKDEMGKMVSVINTVDTSHEDMIHDAQMDYYGTRLATCSS : .. ..:.:.:::...:..: :.::::: CCDS32 MFVARSIAADHKDLIHDVSFDFHGRRMATCSS 10 20 30 80 90 100 110 120 130 pF1KB6 DRSVKIFDVRNGGQI-LIADLRGHEGPVWQVAWAHPMYGNILASCSYDRKVIIWREENGT :.:::..: ..:. :. . : : ::.:.:::: .:..:::::.:: . .:.: : CCDS32 DQSVKVWDKSESGDWHCTASWKTHSGSVWRVTWAHPEFGQVLASCSFDRTAAVWEEIVGE 40 50 60 70 80 90 140 150 160 170 180 pF1KB6 ----------WEKSHEHAGHDSSVNSVCWAPHDYGLILACGSSDGAISLLT---YTGEGQ : : . .::..: .::. .::.:: :.:: . . . .: CCDS32 SNDKLRGQSHWVKRTTLVDSRTSVTDVKFAPKHMGLMLATCSADGIVRIYEAPDVMNLSQ 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB6 WEVKKINNAHTIGCNAVSWAPAV--VPGSLIDHPSGQK-PNYIKRFASGGCDNLIKLWKE : ... . . ..:. .:: :. . . .: : .. :: . . ..... CCDS32 WSLQH-EISCKLSCSCISWNPSSSRAHSPMIAVGSDDSSPNAMAK---------VQIFEY 160 170 180 190 200 250 260 270 280 290 300 pF1KB6 EEDG-QWKEEQKLEAHSDWVRDVAWAPSIGLPTSTIASCSQDGRVF-IWTCDDASSNTWS .:. .. . . : . .: :.:.:.::..: .: ..: :.: . ... . CCDS32 NENTRKYAKAETLMTVTDPVHDIAFAPNLGRSFHILAIATKDVRIFTLKPVRKELTSSGG 210 220 230 240 250 260 310 320 330 340 350 pF1KB6 P-----KLLHKF---NDVVWHVSWSITANILAVSGGDNKVTLWKESVDGQWVCISDVNKG : ... .: :. ::.:::.::...:: :: :. : ::: . .: : . . :: CCDS32 PTKFEIHIVAQFDNHNSQVWRVSWNITGTVLASSGDDGCVRLWKANYMDNWKC-TGILKG 270 280 290 300 310 320 360 pF1KB6 QGS-VSASVTEGQQNEQ .:: :..: .: .: CCDS32 NGSPVNGSSQQGTSNPSLGSTIPSLQNSLNGSSAGRYFFTPLDSPRAGSRWSSYAQLLPP 330 340 350 360 370 380 368 residues in 1 query sequences 18511270 residues in 32554 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 16:10:10 2016 done: Fri Nov 4 16:10:10 2016 Total Scan time: 2.460 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]