FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6539, 368 aa 1>>>pF1KB6539 368 - 368 aa - 368 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.3936+/-0.000427; mu= 16.4794+/- 0.026 mean_var=100.1705+/-20.620, 0's: 0 Z-trim(113.6): 143 B-trim: 692 in 1/50 Lambda= 0.128146 statistics sampled from 22789 (22971) to 22789 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.634), E-opt: 0.2 (0.269), width: 16 Scan time: 6.900 The best scores are: opt bits E(85289) NP_001129498 (OMIM: 600152) protein SEC13 homolog ( 368) 2591 489.8 4e-138 XP_016862508 (OMIM: 600152) PREDICTED: protein SEC ( 368) 2591 489.8 4e-138 NP_109598 (OMIM: 600152) protein SEC13 homolog iso ( 325) 2288 433.8 2.7e-121 XP_005265436 (OMIM: 600152) PREDICTED: protein SEC ( 325) 2288 433.8 2.7e-121 NP_899195 (OMIM: 600152) protein SEC13 homolog iso ( 322) 2267 429.9 3.9e-120 NP_001129704 (OMIM: 600152) protein SEC13 homolog ( 308) 2181 414.0 2.3e-115 XP_016862509 (OMIM: 600152) PREDICTED: protein SEC ( 301) 2039 387.7 1.8e-107 XP_016862510 (OMIM: 600152) PREDICTED: protein SEC ( 298) 2018 383.8 2.7e-106 NP_001265875 (OMIM: 600152) protein SEC13 homolog ( 194) 1054 205.4 8.9e-53 NP_112493 (OMIM: 609263) nucleoporin SEH1 isoform ( 360) 346 74.8 3.5e-13 NP_001013455 (OMIM: 609263) nucleoporin SEH1 isofo ( 421) 346 74.9 3.9e-13 XP_011524046 (OMIM: 609263) PREDICTED: nucleoporin ( 380) 316 69.3 1.7e-11 XP_011524044 (OMIM: 609263) PREDICTED: nucleoporin ( 441) 316 69.3 1.9e-11 NP_004795 (OMIM: 604333) probable cytosolic iron-s ( 339) 255 57.9 3.8e-08 NP_060726 (OMIM: 616620) ribosome biogenesis prote ( 423) 195 46.9 9.8e-05 XP_016881514 (OMIM: 609263) PREDICTED: nucleoporin ( 311) 184 44.8 0.00032 XP_005258209 (OMIM: 609263) PREDICTED: nucleoporin ( 372) 184 44.9 0.00037 XP_011524045 (OMIM: 609263) PREDICTED: nucleoporin ( 392) 184 44.9 0.00038 XP_011509771 (OMIM: 616620) PREDICTED: ribosome bi ( 285) 180 44.0 0.00051 NP_002884 (OMIM: 300825) histone-binding protein R ( 425) 171 42.5 0.0021 NP_001185648 (OMIM: 300825) histone-binding protei ( 469) 171 42.6 0.0023 XP_016881516 (OMIM: 609263) PREDICTED: nucleoporin ( 235) 166 41.3 0.0027 XP_011524048 (OMIM: 609263) PREDICTED: nucleoporin ( 296) 166 41.4 0.0031 XP_016881515 (OMIM: 609263) PREDICTED: nucleoporin ( 296) 166 41.4 0.0031 XP_011524047 (OMIM: 609263) PREDICTED: nucleoporin ( 316) 166 41.5 0.0033 XP_005267076 (OMIM: 215100,266500,601757,614879) P ( 285) 163 40.9 0.0045 NP_000279 (OMIM: 215100,266500,601757,614879) pero ( 323) 163 40.9 0.0049 XP_016866423 (OMIM: 215100,266500,601757,614879) P ( 199) 160 40.1 0.0052 NP_620640 (OMIM: 601787) transcription initiation ( 745) 166 41.8 0.0059 NP_008882 (OMIM: 601787) transcription initiation ( 800) 166 41.9 0.0062 NP_001273158 (OMIM: 610617) denticleless protein h ( 459) 163 41.1 0.0063 NP_001308124 (OMIM: 270710,602342,608628,616944) F ( 427) 162 40.9 0.0068 NP_001310943 (OMIM: 605002) coronin-2B isoform 2 [ ( 475) 162 40.9 0.0073 NP_001177385 (OMIM: 605002) coronin-2B isoform 2 [ ( 475) 162 40.9 0.0073 NP_001177386 (OMIM: 605002) coronin-2B isoform 2 [ ( 475) 162 40.9 0.0073 NP_001310944 (OMIM: 605002) coronin-2B isoform 2 [ ( 475) 162 40.9 0.0073 NP_006082 (OMIM: 605002) coronin-2B isoform 1 [Hom ( 480) 162 40.9 0.0073 XP_011511443 (OMIM: 270710,602342,608628,616944) P ( 514) 162 40.9 0.0077 XP_016862674 (OMIM: 270710,602342,608628,616944) P ( 514) 162 40.9 0.0077 NP_078941 (OMIM: 270710,602342,608628,616944) F-bo ( 514) 162 40.9 0.0077 XP_011511444 (OMIM: 270710,602342,608628,616944) P ( 514) 162 40.9 0.0077 NP_001308122 (OMIM: 270710,602342,608628,616944) F ( 514) 162 40.9 0.0077 XP_006713809 (OMIM: 270710,602342,608628,616944) P ( 514) 162 40.9 0.0077 XP_011511445 (OMIM: 270710,602342,608628,616944) P ( 514) 162 40.9 0.0077 NP_001308123 (OMIM: 270710,602342,608628,616944) F ( 514) 162 40.9 0.0077 XP_005247832 (OMIM: 270710,602342,608628,616944) P ( 514) 162 40.9 0.0077 XP_011507916 (OMIM: 610617) PREDICTED: denticleles ( 668) 163 41.2 0.0081 NP_001273159 (OMIM: 610617) denticleless protein h ( 688) 163 41.2 0.0083 NP_057532 (OMIM: 610617) denticleless protein homo ( 730) 163 41.3 0.0086 >>NP_001129498 (OMIM: 600152) protein SEC13 homolog isof (368 aa) initn: 2591 init1: 2591 opt: 2591 Z-score: 2600.7 bits: 489.8 E(85289): 4e-138 Smith-Waterman score: 2591; 100.0% identity (100.0% similar) in 368 aa overlap (1-368:1-368) 10 20 30 40 50 60 pF1KB6 MREPVLTWCVPLELLCSHPLPLSAFLKSQVKLYTYRACAGKDEMGKMVSVINTVDTSHED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MREPVLTWCVPLELLCSHPLPLSAFLKSQVKLYTYRACAGKDEMGKMVSVINTVDTSHED 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 MIHDAQMDYYGTRLATCSSDRSVKIFDVRNGGQILIADLRGHEGPVWQVAWAHPMYGNIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MIHDAQMDYYGTRLATCSSDRSVKIFDVRNGGQILIADLRGHEGPVWQVAWAHPMYGNIL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 ASCSYDRKVIIWREENGTWEKSHEHAGHDSSVNSVCWAPHDYGLILACGSSDGAISLLTY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ASCSYDRKVIIWREENGTWEKSHEHAGHDSSVNSVCWAPHDYGLILACGSSDGAISLLTY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 TGEGQWEVKKINNAHTIGCNAVSWAPAVVPGSLIDHPSGQKPNYIKRFASGGCDNLIKLW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TGEGQWEVKKINNAHTIGCNAVSWAPAVVPGSLIDHPSGQKPNYIKRFASGGCDNLIKLW 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 KEEEDGQWKEEQKLEAHSDWVRDVAWAPSIGLPTSTIASCSQDGRVFIWTCDDASSNTWS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 KEEEDGQWKEEQKLEAHSDWVRDVAWAPSIGLPTSTIASCSQDGRVFIWTCDDASSNTWS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 PKLLHKFNDVVWHVSWSITANILAVSGGDNKVTLWKESVDGQWVCISDVNKGQGSVSASV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 PKLLHKFNDVVWHVSWSITANILAVSGGDNKVTLWKESVDGQWVCISDVNKGQGSVSASV 310 320 330 340 350 360 pF1KB6 TEGQQNEQ :::::::: NP_001 TEGQQNEQ >>XP_016862508 (OMIM: 600152) PREDICTED: protein SEC13 h (368 aa) initn: 2591 init1: 2591 opt: 2591 Z-score: 2600.7 bits: 489.8 E(85289): 4e-138 Smith-Waterman score: 2591; 100.0% identity (100.0% similar) in 368 aa overlap (1-368:1-368) 10 20 30 40 50 60 pF1KB6 MREPVLTWCVPLELLCSHPLPLSAFLKSQVKLYTYRACAGKDEMGKMVSVINTVDTSHED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MREPVLTWCVPLELLCSHPLPLSAFLKSQVKLYTYRACAGKDEMGKMVSVINTVDTSHED 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 MIHDAQMDYYGTRLATCSSDRSVKIFDVRNGGQILIADLRGHEGPVWQVAWAHPMYGNIL :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MIHDAQMDYYGTRLATCSSDRSVKIFDVRNGGQILIADLRGHEGPVWQVAWAHPMYGNIL 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 ASCSYDRKVIIWREENGTWEKSHEHAGHDSSVNSVCWAPHDYGLILACGSSDGAISLLTY :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ASCSYDRKVIIWREENGTWEKSHEHAGHDSSVNSVCWAPHDYGLILACGSSDGAISLLTY 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 TGEGQWEVKKINNAHTIGCNAVSWAPAVVPGSLIDHPSGQKPNYIKRFASGGCDNLIKLW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 TGEGQWEVKKINNAHTIGCNAVSWAPAVVPGSLIDHPSGQKPNYIKRFASGGCDNLIKLW 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 KEEEDGQWKEEQKLEAHSDWVRDVAWAPSIGLPTSTIASCSQDGRVFIWTCDDASSNTWS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 KEEEDGQWKEEQKLEAHSDWVRDVAWAPSIGLPTSTIASCSQDGRVFIWTCDDASSNTWS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 PKLLHKFNDVVWHVSWSITANILAVSGGDNKVTLWKESVDGQWVCISDVNKGQGSVSASV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PKLLHKFNDVVWHVSWSITANILAVSGGDNKVTLWKESVDGQWVCISDVNKGQGSVSASV 310 320 330 340 350 360 pF1KB6 TEGQQNEQ :::::::: XP_016 TEGQQNEQ >>NP_109598 (OMIM: 600152) protein SEC13 homolog isoform (325 aa) initn: 2288 init1: 2288 opt: 2288 Z-score: 2298.6 bits: 433.8 E(85289): 2.7e-121 Smith-Waterman score: 2288; 100.0% identity (100.0% similar) in 325 aa overlap (44-368:1-325) 20 30 40 50 60 70 pF1KB6 LLCSHPLPLSAFLKSQVKLYTYRACAGKDEMGKMVSVINTVDTSHEDMIHDAQMDYYGTR :::::::::::::::::::::::::::::: NP_109 MGKMVSVINTVDTSHEDMIHDAQMDYYGTR 10 20 30 80 90 100 110 120 130 pF1KB6 LATCSSDRSVKIFDVRNGGQILIADLRGHEGPVWQVAWAHPMYGNILASCSYDRKVIIWR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_109 LATCSSDRSVKIFDVRNGGQILIADLRGHEGPVWQVAWAHPMYGNILASCSYDRKVIIWR 40 50 60 70 80 90 140 150 160 170 180 190 pF1KB6 EENGTWEKSHEHAGHDSSVNSVCWAPHDYGLILACGSSDGAISLLTYTGEGQWEVKKINN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_109 EENGTWEKSHEHAGHDSSVNSVCWAPHDYGLILACGSSDGAISLLTYTGEGQWEVKKINN 100 110 120 130 140 150 200 210 220 230 240 250 pF1KB6 AHTIGCNAVSWAPAVVPGSLIDHPSGQKPNYIKRFASGGCDNLIKLWKEEEDGQWKEEQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_109 AHTIGCNAVSWAPAVVPGSLIDHPSGQKPNYIKRFASGGCDNLIKLWKEEEDGQWKEEQK 160 170 180 190 200 210 260 270 280 290 300 310 pF1KB6 LEAHSDWVRDVAWAPSIGLPTSTIASCSQDGRVFIWTCDDASSNTWSPKLLHKFNDVVWH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_109 LEAHSDWVRDVAWAPSIGLPTSTIASCSQDGRVFIWTCDDASSNTWSPKLLHKFNDVVWH 220 230 240 250 260 270 320 330 340 350 360 pF1KB6 VSWSITANILAVSGGDNKVTLWKESVDGQWVCISDVNKGQGSVSASVTEGQQNEQ ::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_109 VSWSITANILAVSGGDNKVTLWKESVDGQWVCISDVNKGQGSVSASVTEGQQNEQ 280 290 300 310 320 >>XP_005265436 (OMIM: 600152) PREDICTED: protein SEC13 h (325 aa) initn: 2288 init1: 2288 opt: 2288 Z-score: 2298.6 bits: 433.8 E(85289): 2.7e-121 Smith-Waterman score: 2288; 100.0% identity (100.0% similar) in 325 aa overlap (44-368:1-325) 20 30 40 50 60 70 pF1KB6 LLCSHPLPLSAFLKSQVKLYTYRACAGKDEMGKMVSVINTVDTSHEDMIHDAQMDYYGTR :::::::::::::::::::::::::::::: XP_005 MGKMVSVINTVDTSHEDMIHDAQMDYYGTR 10 20 30 80 90 100 110 120 130 pF1KB6 LATCSSDRSVKIFDVRNGGQILIADLRGHEGPVWQVAWAHPMYGNILASCSYDRKVIIWR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LATCSSDRSVKIFDVRNGGQILIADLRGHEGPVWQVAWAHPMYGNILASCSYDRKVIIWR 40 50 60 70 80 90 140 150 160 170 180 190 pF1KB6 EENGTWEKSHEHAGHDSSVNSVCWAPHDYGLILACGSSDGAISLLTYTGEGQWEVKKINN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 EENGTWEKSHEHAGHDSSVNSVCWAPHDYGLILACGSSDGAISLLTYTGEGQWEVKKINN 100 110 120 130 140 150 200 210 220 230 240 250 pF1KB6 AHTIGCNAVSWAPAVVPGSLIDHPSGQKPNYIKRFASGGCDNLIKLWKEEEDGQWKEEQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AHTIGCNAVSWAPAVVPGSLIDHPSGQKPNYIKRFASGGCDNLIKLWKEEEDGQWKEEQK 160 170 180 190 200 210 260 270 280 290 300 310 pF1KB6 LEAHSDWVRDVAWAPSIGLPTSTIASCSQDGRVFIWTCDDASSNTWSPKLLHKFNDVVWH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LEAHSDWVRDVAWAPSIGLPTSTIASCSQDGRVFIWTCDDASSNTWSPKLLHKFNDVVWH 220 230 240 250 260 270 320 330 340 350 360 pF1KB6 VSWSITANILAVSGGDNKVTLWKESVDGQWVCISDVNKGQGSVSASVTEGQQNEQ ::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 VSWSITANILAVSGGDNKVTLWKESVDGQWVCISDVNKGQGSVSASVTEGQQNEQ 280 290 300 310 320 >>NP_899195 (OMIM: 600152) protein SEC13 homolog isoform (322 aa) initn: 2267 init1: 2267 opt: 2267 Z-score: 2277.7 bits: 429.9 E(85289): 3.9e-120 Smith-Waterman score: 2267; 100.0% identity (100.0% similar) in 322 aa overlap (47-368:1-322) 20 30 40 50 60 70 pF1KB6 SHPLPLSAFLKSQVKLYTYRACAGKDEMGKMVSVINTVDTSHEDMIHDAQMDYYGTRLAT :::::::::::::::::::::::::::::: NP_899 MVSVINTVDTSHEDMIHDAQMDYYGTRLAT 10 20 30 80 90 100 110 120 130 pF1KB6 CSSDRSVKIFDVRNGGQILIADLRGHEGPVWQVAWAHPMYGNILASCSYDRKVIIWREEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_899 CSSDRSVKIFDVRNGGQILIADLRGHEGPVWQVAWAHPMYGNILASCSYDRKVIIWREEN 40 50 60 70 80 90 140 150 160 170 180 190 pF1KB6 GTWEKSHEHAGHDSSVNSVCWAPHDYGLILACGSSDGAISLLTYTGEGQWEVKKINNAHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_899 GTWEKSHEHAGHDSSVNSVCWAPHDYGLILACGSSDGAISLLTYTGEGQWEVKKINNAHT 100 110 120 130 140 150 200 210 220 230 240 250 pF1KB6 IGCNAVSWAPAVVPGSLIDHPSGQKPNYIKRFASGGCDNLIKLWKEEEDGQWKEEQKLEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_899 IGCNAVSWAPAVVPGSLIDHPSGQKPNYIKRFASGGCDNLIKLWKEEEDGQWKEEQKLEA 160 170 180 190 200 210 260 270 280 290 300 310 pF1KB6 HSDWVRDVAWAPSIGLPTSTIASCSQDGRVFIWTCDDASSNTWSPKLLHKFNDVVWHVSW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_899 HSDWVRDVAWAPSIGLPTSTIASCSQDGRVFIWTCDDASSNTWSPKLLHKFNDVVWHVSW 220 230 240 250 260 270 320 330 340 350 360 pF1KB6 SITANILAVSGGDNKVTLWKESVDGQWVCISDVNKGQGSVSASVTEGQQNEQ :::::::::::::::::::::::::::::::::::::::::::::::::::: NP_899 SITANILAVSGGDNKVTLWKESVDGQWVCISDVNKGQGSVSASVTEGQQNEQ 280 290 300 310 320 >>NP_001129704 (OMIM: 600152) protein SEC13 homolog isof (308 aa) initn: 2181 init1: 2181 opt: 2181 Z-score: 2192.0 bits: 414.0 E(85289): 2.3e-115 Smith-Waterman score: 2181; 100.0% identity (100.0% similar) in 308 aa overlap (61-368:1-308) 40 50 60 70 80 90 pF1KB6 KLYTYRACAGKDEMGKMVSVINTVDTSHEDMIHDAQMDYYGTRLATCSSDRSVKIFDVRN :::::::::::::::::::::::::::::: NP_001 MIHDAQMDYYGTRLATCSSDRSVKIFDVRN 10 20 30 100 110 120 130 140 150 pF1KB6 GGQILIADLRGHEGPVWQVAWAHPMYGNILASCSYDRKVIIWREENGTWEKSHEHAGHDS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GGQILIADLRGHEGPVWQVAWAHPMYGNILASCSYDRKVIIWREENGTWEKSHEHAGHDS 40 50 60 70 80 90 160 170 180 190 200 210 pF1KB6 SVNSVCWAPHDYGLILACGSSDGAISLLTYTGEGQWEVKKINNAHTIGCNAVSWAPAVVP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SVNSVCWAPHDYGLILACGSSDGAISLLTYTGEGQWEVKKINNAHTIGCNAVSWAPAVVP 100 110 120 130 140 150 220 230 240 250 260 270 pF1KB6 GSLIDHPSGQKPNYIKRFASGGCDNLIKLWKEEEDGQWKEEQKLEAHSDWVRDVAWAPSI :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GSLIDHPSGQKPNYIKRFASGGCDNLIKLWKEEEDGQWKEEQKLEAHSDWVRDVAWAPSI 160 170 180 190 200 210 280 290 300 310 320 330 pF1KB6 GLPTSTIASCSQDGRVFIWTCDDASSNTWSPKLLHKFNDVVWHVSWSITANILAVSGGDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GLPTSTIASCSQDGRVFIWTCDDASSNTWSPKLLHKFNDVVWHVSWSITANILAVSGGDN 220 230 240 250 260 270 340 350 360 pF1KB6 KVTLWKESVDGQWVCISDVNKGQGSVSASVTEGQQNEQ :::::::::::::::::::::::::::::::::::::: NP_001 KVTLWKESVDGQWVCISDVNKGQGSVSASVTEGQQNEQ 280 290 300 >>XP_016862509 (OMIM: 600152) PREDICTED: protein SEC13 h (301 aa) initn: 2207 init1: 2039 opt: 2039 Z-score: 2050.3 bits: 387.7 E(85289): 1.8e-107 Smith-Waterman score: 2039; 99.3% identity (99.3% similar) in 291 aa overlap (44-334:1-291) 20 30 40 50 60 70 pF1KB6 LLCSHPLPLSAFLKSQVKLYTYRACAGKDEMGKMVSVINTVDTSHEDMIHDAQMDYYGTR :::::::::::::::::::::::::::::: XP_016 MGKMVSVINTVDTSHEDMIHDAQMDYYGTR 10 20 30 80 90 100 110 120 130 pF1KB6 LATCSSDRSVKIFDVRNGGQILIADLRGHEGPVWQVAWAHPMYGNILASCSYDRKVIIWR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LATCSSDRSVKIFDVRNGGQILIADLRGHEGPVWQVAWAHPMYGNILASCSYDRKVIIWR 40 50 60 70 80 90 140 150 160 170 180 190 pF1KB6 EENGTWEKSHEHAGHDSSVNSVCWAPHDYGLILACGSSDGAISLLTYTGEGQWEVKKINN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 EENGTWEKSHEHAGHDSSVNSVCWAPHDYGLILACGSSDGAISLLTYTGEGQWEVKKINN 100 110 120 130 140 150 200 210 220 230 240 250 pF1KB6 AHTIGCNAVSWAPAVVPGSLIDHPSGQKPNYIKRFASGGCDNLIKLWKEEEDGQWKEEQK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 AHTIGCNAVSWAPAVVPGSLIDHPSGQKPNYIKRFASGGCDNLIKLWKEEEDGQWKEEQK 160 170 180 190 200 210 260 270 280 290 300 310 pF1KB6 LEAHSDWVRDVAWAPSIGLPTSTIASCSQDGRVFIWTCDDASSNTWSPKLLHKFNDVVWH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 LEAHSDWVRDVAWAPSIGLPTSTIASCSQDGRVFIWTCDDASSNTWSPKLLHKFNDVVWH 220 230 240 250 260 270 320 330 340 350 360 pF1KB6 VSWSITANILAVSGGDNKVTLWKESVDGQWVCISDVNKGQGSVSASVTEGQQNEQ :::::::::::::::::: : XP_016 VSWSITANILAVSGGDNKEELQMQPQIDHLP 280 290 300 >>XP_016862510 (OMIM: 600152) PREDICTED: protein SEC13 h (298 aa) initn: 2186 init1: 2018 opt: 2018 Z-score: 2029.3 bits: 383.8 E(85289): 2.7e-106 Smith-Waterman score: 2018; 99.3% identity (99.3% similar) in 288 aa overlap (47-334:1-288) 20 30 40 50 60 70 pF1KB6 SHPLPLSAFLKSQVKLYTYRACAGKDEMGKMVSVINTVDTSHEDMIHDAQMDYYGTRLAT :::::::::::::::::::::::::::::: XP_016 MVSVINTVDTSHEDMIHDAQMDYYGTRLAT 10 20 30 80 90 100 110 120 130 pF1KB6 CSSDRSVKIFDVRNGGQILIADLRGHEGPVWQVAWAHPMYGNILASCSYDRKVIIWREEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 CSSDRSVKIFDVRNGGQILIADLRGHEGPVWQVAWAHPMYGNILASCSYDRKVIIWREEN 40 50 60 70 80 90 140 150 160 170 180 190 pF1KB6 GTWEKSHEHAGHDSSVNSVCWAPHDYGLILACGSSDGAISLLTYTGEGQWEVKKINNAHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 GTWEKSHEHAGHDSSVNSVCWAPHDYGLILACGSSDGAISLLTYTGEGQWEVKKINNAHT 100 110 120 130 140 150 200 210 220 230 240 250 pF1KB6 IGCNAVSWAPAVVPGSLIDHPSGQKPNYIKRFASGGCDNLIKLWKEEEDGQWKEEQKLEA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 IGCNAVSWAPAVVPGSLIDHPSGQKPNYIKRFASGGCDNLIKLWKEEEDGQWKEEQKLEA 160 170 180 190 200 210 260 270 280 290 300 310 pF1KB6 HSDWVRDVAWAPSIGLPTSTIASCSQDGRVFIWTCDDASSNTWSPKLLHKFNDVVWHVSW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 HSDWVRDVAWAPSIGLPTSTIASCSQDGRVFIWTCDDASSNTWSPKLLHKFNDVVWHVSW 220 230 240 250 260 270 320 330 340 350 360 pF1KB6 SITANILAVSGGDNKVTLWKESVDGQWVCISDVNKGQGSVSASVTEGQQNEQ ::::::::::::::: : XP_016 SITANILAVSGGDNKEELQMQPQIDHLP 280 290 >>NP_001265875 (OMIM: 600152) protein SEC13 homolog isof (194 aa) initn: 1188 init1: 1054 opt: 1054 Z-score: 1068.5 bits: 205.4 E(85289): 8.9e-53 Smith-Waterman score: 1054; 99.3% identity (100.0% similar) in 151 aa overlap (47-197:1-151) 20 30 40 50 60 70 pF1KB6 SHPLPLSAFLKSQVKLYTYRACAGKDEMGKMVSVINTVDTSHEDMIHDAQMDYYGTRLAT :::::::::::::::::::::::::::::: NP_001 MVSVINTVDTSHEDMIHDAQMDYYGTRLAT 10 20 30 80 90 100 110 120 130 pF1KB6 CSSDRSVKIFDVRNGGQILIADLRGHEGPVWQVAWAHPMYGNILASCSYDRKVIIWREEN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 CSSDRSVKIFDVRNGGQILIADLRGHEGPVWQVAWAHPMYGNILASCSYDRKVIIWREEN 40 50 60 70 80 90 140 150 160 170 180 190 pF1KB6 GTWEKSHEHAGHDSSVNSVCWAPHDYGLILACGSSDGAISLLTYTGEGQWEVKKINNAHT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 GTWEKSHEHAGHDSSVNSVCWAPHDYGLILACGSSDGAISLLTYTGEGQWEVKKINNAHT 100 110 120 130 140 150 200 210 220 230 240 250 pF1KB6 IGCNAVSWAPAVVPGSLIDHPSGQKPNYIKRFASGGCDNLIKLWKEEEDGQWKEEQKLEA . NP_001 VSPSPAFRAVRAPALPRVCCSLPRGWHGRVPAGQWAGEWSADQT 160 170 180 190 >>NP_112493 (OMIM: 609263) nucleoporin SEH1 isoform 2 [H (360 aa) initn: 493 init1: 158 opt: 346 Z-score: 357.7 bits: 74.8 E(85289): 3.5e-13 Smith-Waterman score: 577; 31.0% identity (61.7% similar) in 345 aa overlap (50-366:3-336) 20 30 40 50 60 70 pF1KB6 LPLSAFLKSQVKLYTYRACAGKDEMGKMVSVINTVDTSHEDMIHDAQMDYYGTRLATCSS : .. ..:.:.:::...:..: :.::::: NP_112 MFVARSIAADHKDLIHDVSFDFHGRRMATCSS 10 20 30 80 90 100 110 120 130 pF1KB6 DRSVKIFDVRNGGQI-LIADLRGHEGPVWQVAWAHPMYGNILASCSYDRKVIIWREENGT :.:::..: ..:. :. . : : ::.:.:::: .:..:::::.:: . .:.: : NP_112 DQSVKVWDKSESGDWHCTASWKTHSGSVWRVTWAHPEFGQVLASCSFDRTAAVWEEIVGE 40 50 60 70 80 90 140 150 160 170 180 pF1KB6 ----------WEKSHEHAGHDSSVNSVCWAPHDYGLILACGSSDGAISLLT---YTGEGQ : : . .::..: .::. .::.:: :.:: . . . .: NP_112 SNDKLRGQSHWVKRTTLVDSRTSVTDVKFAPKHMGLMLATCSADGIVRIYEAPDVMNLSQ 100 110 120 130 140 150 190 200 210 220 230 240 pF1KB6 WEVKKINNAHTIGCNAVSWAPAV--VPGSLIDHPSGQK-PNYIKRFASGGCDNLIKLWKE : ... . . ..:. .:: :. . . .: : .. :: . . ..... NP_112 WSLQH-EISCKLSCSCISWNPSSSRAHSPMIAVGSDDSSPNAMAK---------VQIFEY 160 170 180 190 200 250 260 270 280 290 300 pF1KB6 EEDG-QWKEEQKLEAHSDWVRDVAWAPSIGLPTSTIASCSQDGRVF-IWTCDDASSNTWS .:. .. . . : . .: :.:.:.::..: .: ..: :.: . ... . NP_112 NENTRKYAKAETLMTVTDPVHDIAFAPNLGRSFHILAIATKDVRIFTLKPVRKELTSSGG 210 220 230 240 250 260 310 320 330 340 350 pF1KB6 P-----KLLHKF---NDVVWHVSWSITANILAVSGGDNKVTLWKESVDGQWVCISDVNKG : ... .: :. ::.:::.::...:: :: :. : ::: . .: : . . :: NP_112 PTKFEIHIVAQFDNHNSQVWRVSWNITGTVLASSGDDGCVRLWKANYMDNWKC-TGILKG 270 280 290 300 310 320 360 pF1KB6 QGS-VSASVTEGQQNEQ .:: :..: .: .: NP_112 NGSPVNGSSQQGTSNPSLGSTIPSLQNSLNGSSAGRKHS 330 340 350 360 368 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 16:10:10 2016 done: Fri Nov 4 16:10:11 2016 Total Scan time: 6.900 Total Display time: 0.020 Function used was FASTA [36.3.4 Apr, 2011]