FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448
Query: pF1KB6543, 369 aa
1>>>pF1KB6543 369 - 369 aa - 369 aa
Library: /omim/omim.rfq.tfa
60827320 residues in 85289 sequences
Statistics: Expectation_n fit: rho(ln(x))= 5.5879+/-0.000328; mu= 15.7347+/- 0.020
mean_var=82.8828+/-16.836, 0's: 0 Z-trim(116.3): 111 B-trim: 0 in 0/54
Lambda= 0.140878
statistics sampled from 27334 (27448) to 27334 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
ktup: 2, E-join: 1 (0.693), E-opt: 0.2 (0.322), width: 16
Scan time: 8.650
The best scores are: opt bits E(85289)
NP_000197 (OMIM: 300400,308380,312863) cytokine re ( 369) 2581 534.2 1.8e-151
NP_000631 (OMIM: 300130) interleukin-13 receptor s ( 380) 316 73.8 7e-13
XP_011528206 (OMIM: 138981,614370) PREDICTED: cyto ( 909) 249 60.5 1.8e-08
NP_000386 (OMIM: 138981,614370) cytokine receptor ( 897) 239 58.5 7.1e-08
XP_011528205 (OMIM: 138981,614370) PREDICTED: cyto ( 915) 232 57.0 1.9e-07
NP_000555 (OMIM: 147851) interleukin-5 receptor su ( 420) 222 54.8 4.3e-07
NP_783853 (OMIM: 147851) interleukin-5 receptor su ( 420) 222 54.8 4.3e-07
XP_011531980 (OMIM: 147851) PREDICTED: interleukin ( 439) 222 54.8 4.4e-07
XP_011531979 (OMIM: 147851) PREDICTED: interleukin ( 439) 222 54.8 4.4e-07
XP_005261397 (OMIM: 138981,614370) PREDICTED: cyto ( 903) 222 55.0 7.8e-07
XP_011544472 (OMIM: 306250,425000) PREDICTED: gran ( 383) 200 50.3 8.9e-06
XP_016884776 (OMIM: 306250,425000) PREDICTED: gran ( 383) 200 50.3 8.9e-06
XP_011543925 (OMIM: 306250,425000) PREDICTED: gran ( 383) 200 50.3 8.9e-06
XP_016885517 (OMIM: 306250,425000) PREDICTED: gran ( 383) 200 50.3 8.9e-06
XP_011543924 (OMIM: 306250,425000) PREDICTED: gran ( 385) 200 50.3 8.9e-06
XP_011544471 (OMIM: 306250,425000) PREDICTED: gran ( 385) 200 50.3 8.9e-06
XP_011543923 (OMIM: 306250,425000) PREDICTED: gran ( 386) 200 50.3 8.9e-06
XP_011544470 (OMIM: 306250,425000) PREDICTED: gran ( 386) 200 50.3 8.9e-06
XP_011543922 (OMIM: 306250,425000) PREDICTED: gran ( 389) 200 50.3 9e-06
XP_011544469 (OMIM: 306250,425000) PREDICTED: gran ( 389) 200 50.3 9e-06
XP_011544468 (OMIM: 306250,425000) PREDICTED: gran ( 400) 200 50.3 9.2e-06
NP_001155001 (OMIM: 306250,425000) granulocyte-mac ( 400) 200 50.3 9.2e-06
NP_006131 (OMIM: 306250,425000) granulocyte-macrop ( 400) 200 50.3 9.2e-06
NP_758448 (OMIM: 306250,425000) granulocyte-macrop ( 400) 200 50.3 9.2e-06
XP_011543921 (OMIM: 306250,425000) PREDICTED: gran ( 400) 200 50.3 9.2e-06
XP_011544467 (OMIM: 306250,425000) PREDICTED: gran ( 410) 200 50.3 9.4e-06
XP_011543920 (OMIM: 306250,425000) PREDICTED: gran ( 410) 200 50.3 9.4e-06
NP_001155003 (OMIM: 306250,425000) granulocyte-mac ( 410) 200 50.3 9.4e-06
NP_000112 (OMIM: 133100,133171) erythropoietin rec ( 508) 198 50.0 1.5e-05
NP_001230028 (OMIM: 147851) interleukin-5 receptor ( 378) 192 48.6 2.7e-05
XP_011544483 (OMIM: 300357,400023) PREDICTED: cyto ( 370) 190 48.2 3.5e-05
XP_011543936 (OMIM: 300357,400023) PREDICTED: cyto ( 370) 190 48.2 3.5e-05
NP_071431 (OMIM: 300357,400023) cytokine receptor- ( 371) 190 48.2 3.5e-05
NP_001551 (OMIM: 300119) interleukin-13 receptor s ( 427) 189 48.1 4.5e-05
XP_011529638 (OMIM: 300119) PREDICTED: interleukin ( 529) 189 48.1 5.4e-05
NP_001155004 (OMIM: 306250,425000) granulocyte-mac ( 267) 180 46.1 0.00011
NP_001155002 (OMIM: 306250,425000) granulocyte-mac ( 434) 165 43.2 0.0014
XP_016885518 (OMIM: 306250,425000) PREDICTED: gran ( 333) 162 42.5 0.0017
NP_758450 (OMIM: 306250,425000) granulocyte-macrop ( 333) 162 42.5 0.0017
XP_011544475 (OMIM: 306250,425000) PREDICTED: gran ( 333) 162 42.5 0.0017
XP_011544476 (OMIM: 306250,425000) PREDICTED: gran ( 333) 162 42.5 0.0017
XP_011543930 (OMIM: 306250,425000) PREDICTED: gran ( 333) 162 42.5 0.0017
XP_016884777 (OMIM: 306250,425000) PREDICTED: gran ( 333) 162 42.5 0.0017
XP_011544477 (OMIM: 306250,425000) PREDICTED: gran ( 333) 162 42.5 0.0017
XP_011543928 (OMIM: 306250,425000) PREDICTED: gran ( 333) 162 42.5 0.0017
XP_011543929 (OMIM: 306250,425000) PREDICTED: gran ( 333) 162 42.5 0.0017
NP_783851 (OMIM: 147851) interleukin-5 receptor su ( 333) 161 42.3 0.0019
NP_783854 (OMIM: 147851) interleukin-5 receptor su ( 333) 161 42.3 0.0019
NP_783855 (OMIM: 147851) interleukin-5 receptor su ( 335) 161 42.3 0.0019
NP_783852 (OMIM: 147851) interleukin-5 receptor su ( 335) 161 42.3 0.0019
>>NP_000197 (OMIM: 300400,308380,312863) cytokine recept (369 aa)
initn: 2581 init1: 2581 opt: 2581 Z-score: 2840.3 bits: 534.2 E(85289): 1.8e-151
Smith-Waterman score: 2581; 100.0% identity (100.0% similar) in 369 aa overlap (1-369:1-369)
10 20 30 40 50 60
pF1KB6 MLKPSLPFTSLLFLQLPLLGVGLNTTILTPNGNEDTTADFFLTTMPTDSLSVSTLPLPEV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 MLKPSLPFTSLLFLQLPLLGVGLNTTILTPNGNEDTTADFFLTTMPTDSLSVSTLPLPEV
10 20 30 40 50 60
70 80 90 100 110 120
pF1KB6 QCFVFNVEYMNCTWNSSSEPQPTNLTLHYWYKNSDNDKVQKCSHYLFSEEITSGCQLQKK
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 QCFVFNVEYMNCTWNSSSEPQPTNLTLHYWYKNSDNDKVQKCSHYLFSEEITSGCQLQKK
70 80 90 100 110 120
130 140 150 160 170 180
pF1KB6 EIHLYQTFVVQLQDPREPRRQATQMLKLQNLVIPWAPENLTLHKLSESQLELNWNNRFLN
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 EIHLYQTFVVQLQDPREPRRQATQMLKLQNLVIPWAPENLTLHKLSESQLELNWNNRFLN
130 140 150 160 170 180
190 200 210 220 230 240
pF1KB6 HCLEHLVQYRTDWDHSWTEQSVDYRHKFSLPSVDGQKRYTFRVRSRFNPLCGSAQHWSEW
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 HCLEHLVQYRTDWDHSWTEQSVDYRHKFSLPSVDGQKRYTFRVRSRFNPLCGSAQHWSEW
190 200 210 220 230 240
250 260 270 280 290 300
pF1KB6 SHPIHWGSNTSKENPFLFALEAVVISVGSMGLIISLLCVYFWLERTMPRIPTLKNLEDLV
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 SHPIHWGSNTSKENPFLFALEAVVISVGSMGLIISLLCVYFWLERTMPRIPTLKNLEDLV
250 260 270 280 290 300
310 320 330 340 350 360
pF1KB6 TEYHGNFSAWSGVSKGLAESLQPDYSERLCLVSEIPPKGGALGEGPGASPCNQHSPYWAP
::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_000 TEYHGNFSAWSGVSKGLAESLQPDYSERLCLVSEIPPKGGALGEGPGASPCNQHSPYWAP
310 320 330 340 350 360
pF1KB6 PCYTLKPET
:::::::::
NP_000 PCYTLKPET
>>NP_000631 (OMIM: 300130) interleukin-13 receptor subun (380 aa)
initn: 189 init1: 97 opt: 316 Z-score: 352.2 bits: 73.8 E(85289): 7e-13
Smith-Waterman score: 316; 25.9% identity (56.6% similar) in 251 aa overlap (31-268:115-360)
10 20 30 40 50 60
pF1KB6 MLKPSLPFTSLLFLQLPLLGVGLNTTILTPNGNEDTTADFFLTTMPTDSLSVSTLPLPEV
::.: . ... ::. . .. . ..
NP_000 ITKNLHYKDGFDLNKGIEAKIHTLLPWQCTNGSE-VQSSWAETTYWISPQGIPETKVQDM
90 100 110 120 130 140
70 80 90 100 110
pF1KB6 QCFVFNVEYMNCTWNSS-SEPQPTNLTLHYWYKNSDNDKVQKCSHYLFSEEITSGCQLQK
.: .: .:. :.:. . . :: .: :::.. :. . .: :. .. . ::..
NP_000 DCVYYNWQYLLCSWKPGIGVLLDTNYNLFYWYEGLDH--ALQCVDYIKADGQNIGCRFPY
150 160 170 180 190 200
120 130 140 150 160 170
pF1KB6 KEIHLYQTFVVQLQDPRE--PRRQATQMLKLQNLVIPWAPENLTLHKLSESQLELNWN--
: :. : . .. : : :.. ..:::.: : : ::. . : ...:.:.
NP_000 LEASDYKDFYICVNGSSENKPIRSSYFTFQLQNIVKPLPPVYLTFTRESSCEIKLKWSIP
210 220 230 240 250 260
180 190 200 210 220 230
pF1KB6 -NRFLNHCLEHLVQYRTDWDHSWTEQSVDYRHKFSLPSVDGQKRYTFRVRSRFNPLCGSA
. . .:... .. : : : . . .:. . ..: ... .. : :::. : :..
NP_000 LGPIPARCFDYEIEIRED-DTTLVTATVE-NETYTLKTTNETRQLCFVVRSKVNIYCSDD
270 280 290 300 310
240 250 260 270 280
pF1KB6 QHWSEWSHPIHW-GSNTSKEN------PFLFALEAVVISVGSMGLIISLLCVYFWLERTM
::::: : : . ::.. :: : : :.. .:
NP_000 GIWSEWSDKQCWEGEDLSKKTLLRFWLPFGFILILVIFVTGLLLRKPNTYPKMIPEFFCD
320 330 340 350 360 370
290 300 310 320 330 340
pF1KB6 PRIPTLKNLEDLVTEYHGNFSAWSGVSKGLAESLQPDYSERLCLVSEIPPKGGALGEGPG
NP_000 T
380
>>XP_011528206 (OMIM: 138981,614370) PREDICTED: cytokine (909 aa)
initn: 121 init1: 61 opt: 249 Z-score: 273.2 bits: 60.5 E(85289): 1.8e-08
Smith-Waterman score: 249; 26.7% identity (52.4% similar) in 296 aa overlap (60-343:248-527)
30 40 50 60 70 80
pF1KB6 PNGNEDTTADFFLTTMPTDSLSVSTLPLPEVQCFVFNVEYMNCTWNSSSEPQPTNLTLHY
..:: .. ..:.:. .: .....
XP_011 PGSRLSGRPSKWSPEVCWDSQPGDEAQPQNLECFFDGAAVLSCSWEVRKEVA-SSVSFGL
220 230 240 250 260 270
90 100 110 120 130 140
pF1KB6 WYKNSDNDKVQKCSHYLF----SEEITSGCQLQKKEIHLYQTFVVQLQDPREPRRQATQM
.:: : . ..:: : : . ::. . . ..:..: ::: : .
XP_011 FYKPSPDAGEEECSPVLREGLGSLHTRHHCQIPVPDPATHGQYIVSVQ----PRR-AEKH
280 290 300 310 320 330
150 160 170 180 190
pF1KB6 LKLQNLVIPWAPENLTLHKLSESQLELNWNN---RF--LNHCLEHLVQYRTD---WDHSW
.: ... : :: .:.. : ..: : :.. :. ..: .: .::: : : :
XP_011 IK-SSVNIQMAPPSLNVTKDGDSY-SLRWETMKMRYEHIDHTFE--IQYRKDTATWKDSK
340 350 360 370 380
200 210 220 230 240 250
pF1KB6 TEQSVDYRHKFSLPSVDGQKRYTFRVRSRFNPLCGSAQHWSEWSHPIHWGSNTSKENPFL
:: ... :...::... . :: ::: : . : :::::. : .... . :.
XP_011 TE-TLQNAHSMALPALEPSTRYWARVRVR-TSRTGYNGIWSEWSEARSWDTESDADIPLS
390 400 410 420 430 440
260 270 280 290 300 310
pF1KB6 FALEAVVISVGSMGLIISLLCVYFWLERTMPRIPTLKNLEDLVTEYHGNFSAWSGVSKGL
: : . . ..::. .: . : . : . :. : : : ..:
XP_011 PRLLEV-LPMWVLALIVIFLTIAVLLALRFCGIYGYR-LRRKWEEKIPNPSKSHLFQNGS
450 460 470 480 490 500
320 330 340 350 360
pF1KB6 AESLQPDYSERLCLVSEIPPKGGALGEGPGASPCNQHSPYWAPPCYTLKPET
:: : : : ..: ::. : :
XP_011 AE-LWPPGSMS-AFTSGSPPHQGPWGSRFPELEGVFPVGFGDSEVSPLTIEDPKHVCDPP
510 520 530 540 550 560
>>NP_000386 (OMIM: 138981,614370) cytokine receptor comm (897 aa)
initn: 121 init1: 58 opt: 239 Z-score: 262.3 bits: 58.5 E(85289): 7.1e-08
Smith-Waterman score: 239; 27.4% identity (57.3% similar) in 248 aa overlap (60-291:248-479)
30 40 50 60 70 80
pF1KB6 PNGNEDTTADFFLTTMPTDSLSVSTLPLPEVQCFVFNVEYMNCTWNSSSEPQPTNLTLHY
..:: .. ..:.:. .: .....
NP_000 PGSRLSGRPSKWSPEVCWDSQPGDEAQPQNLECFFDGAAVLSCSWEVRKEVA-SSVSFGL
220 230 240 250 260 270
90 100 110 120 130 140
pF1KB6 WYKNSDNDKVQKCSHYLF----SEEITSGCQLQKKEIHLYQTFVVQLQDPREPRRQATQM
.:: : . ..:: : : . ::. . . ..:..: ::: : .
NP_000 FYKPSPDAGEEECSPVLREGLGSLHTRHHCQIPVPDPATHGQYIVSVQ----PRR-AEKH
280 290 300 310 320 330
150 160 170 180 190
pF1KB6 LKLQNLVIPWAPENLTLHKLSESQLELNWNN---RF--LNHCLEHLVQYRTD---WDHSW
.: ... : :: .:.. : ..: : :.. :. ..: .: .::: : : :
NP_000 IK-SSVNIQMAPPSLNVTKDGDSY-SLRWETMKMRYEHIDHTFE--IQYRKDTATWKDSK
340 350 360 370 380
200 210 220 230 240 250
pF1KB6 TEQSVDYRHKFSLPSVDGQKRYTFRVRSRFNPLCGSAQHWSEWSHPIHWGSNTSKENPFL
:: ... :...::... . :: ::: : . : :::::. : .: . : .
NP_000 TE-TLQNAHSMALPALEPSTRYWARVRVRTSRT-GYNGIWSEWSEARSW--DTESVLP-M
390 400 410 420 430 440
260 270 280 290 300 310
pF1KB6 FALEAVVISVGSMGLIISL-LC-VY-FWLERTMP-RIPTLKNLEDLVTEYHGNFSAWSGV
..: .:: . .......: .: .: . :.: .::
NP_000 WVLALIVIFL-TIAVLLALRFCGIYGYRLRRKWEEKIPNPSKSHLFQNGSAELWPPGSMS
450 460 470 480 490 500
320 330 340 350 360
pF1KB6 SKGLAESLQPDYSERLCLVSEIPPKGGALGEGPGASPCNQHSPYWAPPCYTLKPET
NP_000 AFTSGSPPHQGPWGSRFPELEGVFPVGFGDSEVSPLTIEDPKHVCDPPSGPDTTPAASDL
510 520 530 540 550 560
>>XP_011528205 (OMIM: 138981,614370) PREDICTED: cytokine (915 aa)
initn: 121 init1: 61 opt: 232 Z-score: 254.5 bits: 57.0 E(85289): 1.9e-07
Smith-Waterman score: 232; 26.2% identity (51.7% similar) in 302 aa overlap (60-343:248-533)
30 40 50 60 70 80
pF1KB6 PNGNEDTTADFFLTTMPTDSLSVSTLPLPEVQCFVFNVEYMNCTWNSSSEPQPTNLTLHY
..:: .. ..:.:. .: .....
XP_011 PGSRLSGRPSKWSPEVCWDSQPGDEAQPQNLECFFDGAAVLSCSWEVRKEVA-SSVSFGL
220 230 240 250 260 270
90 100 110 120 130
pF1KB6 WYKNSDND------KVQKCSHYLF----SEEITSGCQLQKKEIHLYQTFVVQLQDPREPR
.:: : . . ..:: : : . ::. . . ..:..: ::
XP_011 FYKPSPDAGSAVLLREEECSPVLREGLGSLHTRHHCQIPVPDPATHGQYIVSVQ----PR
280 290 300 310 320 330
140 150 160 170 180 190
pF1KB6 RQATQMLKLQNLVIPWAPENLTLHKLSESQLELNWNN---RF--LNHCLEHLVQYRTD--
: : . .: ... : :: .:.. : ..: : :.. :. ..: .: .::: :
XP_011 R-AEKHIK-SSVNIQMAPPSLNVTKDGDSY-SLRWETMKMRYEHIDHTFE--IQYRKDTA
340 350 360 370 380
200 210 220 230 240 250
pF1KB6 -WDHSWTEQSVDYRHKFSLPSVDGQKRYTFRVRSRFNPLCGSAQHWSEWSHPIHWGSNTS
: : :: ... :...::... . :: ::: : . : :::::. : ....
XP_011 TWKDSKTE-TLQNAHSMALPALEPSTRYWARVRVR-TSRTGYNGIWSEWSEARSWDTESD
390 400 410 420 430 440
260 270 280 290 300 310
pF1KB6 KENPFLFALEAVVISVGSMGLIISLLCVYFWLERTMPRIPTLKNLEDLVTEYHGNFSAWS
. :. : : . . ..::. .: . : . : . :. : : :
XP_011 ADIPLSPRLLEV-LPMWVLALIVIFLTIAVLLALRFCGIYGYR-LRRKWEEKIPNPSKSH
450 460 470 480 490 500
320 330 340 350 360
pF1KB6 GVSKGLAESLQPDYSERLCLVSEIPPKGGALGEGPGASPCNQHSPYWAPPCYTLKPET
..: :: : : : ..: ::. : :
XP_011 LFQNGSAE-LWPPGSMS-AFTSGSPPHQGPWGSRFPELEGVFPVGFGDSEVSPLTIEDPK
510 520 530 540 550 560
XP_011 HVCDPPSGPDTTPAASDLPTEQPPSPQPGPPAASHTPEKQASSFDFNGPYLGPPHSRSLP
570 580 590 600 610 620
>>NP_000555 (OMIM: 147851) interleukin-5 receptor subuni (420 aa)
initn: 165 init1: 117 opt: 222 Z-score: 248.3 bits: 54.8 E(85289): 4.3e-07
Smith-Waterman score: 222; 23.7% identity (58.5% similar) in 241 aa overlap (70-299:153-385)
40 50 60 70 80 90
pF1KB6 FFLTTMPTDSLSVSTLPLPEVQCFVFNVEYMNCTWNSSSE-PQPTNLTLHYWYKNSDNDK
..::: ... :. :. :.: : .: ...
NP_000 GSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGTDAPEDTQYFLYYRY-GSWTEE
130 140 150 160 170 180
100 110 120 130 140 150
pF1KB6 VQKCSHYLFSEEITSGCQLQKKEI----HLYQTFVVQLQDPREPRRQATQMLKLQNLVIP
:. :. ....:. : . . : . . . .:. .. . : :.. :. .
NP_000 CQEYSKDTLGRNIA--CWFPRTFILSKGRDWLAVLVNGSSKHSAIRPFDQLFALHAIDQI
190 200 210 220 230
160 170 180 190 200 210
pF1KB6 WAPENLTLHKLSESQLELNWN---NRFLNHCLEHLVQYRTDWDHSWTEQSVDYRHKFSLP
: :.: .. ..: ..:. . : ::... :. . . ... . . . : .
NP_000 NPPLNVTA-EIEGTRLSIQWEKPVSAFPIHCFDYEVKIH-NTRNGYLQIEKLMTNAF-IS
240 250 260 270 280 290
220 230 240 250 260 270
pF1KB6 SVDGQKRYTFRVRSRFNPLCGSAQHWSEWSHPIHWGSNTSKENPFLFALEAVVISVGSMG
.: ..: .::. . .: : :::::.::. :.. : :.. ... .. .
NP_000 IIDDLSKYDVQVRAAVSSMCREAGLWSEWSQPIYVGNDEHKPLREWFVI-VIMATICFIL
300 310 320 330 340 350
280 290 300 310 320
pF1KB6 LIISLLC--VYFWLERTMPRIPTLK-NLEDLVTEYHGNFSAWSGVSKGLAESLQPDYSER
::.::.: ..:. . .: ::. : :..::
NP_000 LILSLICKICHLWI-KLFPPIPAPKSNIKDLFVTTNYEKAGSSETEIEVICYIEKPGVET
360 370 380 390 400 410
330 340 350 360
pF1KB6 LCLVSEIPPKGGALGEGPGASPCNQHSPYWAPPCYTLKPET
NP_000 LEDSVF
420
>>NP_783853 (OMIM: 147851) interleukin-5 receptor subuni (420 aa)
initn: 165 init1: 117 opt: 222 Z-score: 248.3 bits: 54.8 E(85289): 4.3e-07
Smith-Waterman score: 222; 23.7% identity (58.5% similar) in 241 aa overlap (70-299:153-385)
40 50 60 70 80 90
pF1KB6 FFLTTMPTDSLSVSTLPLPEVQCFVFNVEYMNCTWNSSSE-PQPTNLTLHYWYKNSDNDK
..::: ... :. :. :.: : .: ...
NP_783 GSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGTDAPEDTQYFLYYRY-GSWTEE
130 140 150 160 170 180
100 110 120 130 140 150
pF1KB6 VQKCSHYLFSEEITSGCQLQKKEI----HLYQTFVVQLQDPREPRRQATQMLKLQNLVIP
:. :. ....:. : . . : . . . .:. .. . : :.. :. .
NP_783 CQEYSKDTLGRNIA--CWFPRTFILSKGRDWLAVLVNGSSKHSAIRPFDQLFALHAIDQI
190 200 210 220 230
160 170 180 190 200 210
pF1KB6 WAPENLTLHKLSESQLELNWN---NRFLNHCLEHLVQYRTDWDHSWTEQSVDYRHKFSLP
: :.: .. ..: ..:. . : ::... :. . . ... . . . : .
NP_783 NPPLNVTA-EIEGTRLSIQWEKPVSAFPIHCFDYEVKIH-NTRNGYLQIEKLMTNAF-IS
240 250 260 270 280 290
220 230 240 250 260 270
pF1KB6 SVDGQKRYTFRVRSRFNPLCGSAQHWSEWSHPIHWGSNTSKENPFLFALEAVVISVGSMG
.: ..: .::. . .: : :::::.::. :.. : :.. ... .. .
NP_783 IIDDLSKYDVQVRAAVSSMCREAGLWSEWSQPIYVGNDEHKPLREWFVI-VIMATICFIL
300 310 320 330 340 350
280 290 300 310 320
pF1KB6 LIISLLC--VYFWLERTMPRIPTLK-NLEDLVTEYHGNFSAWSGVSKGLAESLQPDYSER
::.::.: ..:. . .: ::. : :..::
NP_783 LILSLICKICHLWI-KLFPPIPAPKSNIKDLFVTTNYEKAGSSETEIEVICYIEKPGVET
360 370 380 390 400 410
330 340 350 360
pF1KB6 LCLVSEIPPKGGALGEGPGASPCNQHSPYWAPPCYTLKPET
NP_783 LEDSVF
420
>>XP_011531980 (OMIM: 147851) PREDICTED: interleukin-5 r (439 aa)
initn: 165 init1: 117 opt: 222 Z-score: 248.1 bits: 54.8 E(85289): 4.4e-07
Smith-Waterman score: 222; 23.7% identity (58.5% similar) in 241 aa overlap (70-299:153-385)
40 50 60 70 80 90
pF1KB6 FFLTTMPTDSLSVSTLPLPEVQCFVFNVEYMNCTWNSSSE-PQPTNLTLHYWYKNSDNDK
..::: ... :. :. :.: : .: ...
XP_011 GSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGTDAPEDTQYFLYYRY-GSWTEE
130 140 150 160 170 180
100 110 120 130 140 150
pF1KB6 VQKCSHYLFSEEITSGCQLQKKEI----HLYQTFVVQLQDPREPRRQATQMLKLQNLVIP
:. :. ....:. : . . : . . . .:. .. . : :.. :. .
XP_011 CQEYSKDTLGRNIA--CWFPRTFILSKGRDWLAVLVNGSSKHSAIRPFDQLFALHAIDQI
190 200 210 220 230
160 170 180 190 200 210
pF1KB6 WAPENLTLHKLSESQLELNWN---NRFLNHCLEHLVQYRTDWDHSWTEQSVDYRHKFSLP
: :.: .. ..: ..:. . : ::... :. . . ... . . . : .
XP_011 NPPLNVTA-EIEGTRLSIQWEKPVSAFPIHCFDYEVKIH-NTRNGYLQIEKLMTNAF-IS
240 250 260 270 280 290
220 230 240 250 260 270
pF1KB6 SVDGQKRYTFRVRSRFNPLCGSAQHWSEWSHPIHWGSNTSKENPFLFALEAVVISVGSMG
.: ..: .::. . .: : :::::.::. :.. : :.. ... .. .
XP_011 IIDDLSKYDVQVRAAVSSMCREAGLWSEWSQPIYVGNDEHKPLREWFVI-VIMATICFIL
300 310 320 330 340 350
280 290 300 310 320
pF1KB6 LIISLLC--VYFWLERTMPRIPTLK-NLEDLVTEYHGNFSAWSGVSKGLAESLQPDYSER
::.::.: ..:. . .: ::. : :..::
XP_011 LILSLICKICHLWI-KLFPPIPAPKSNIKDLFVTTNYEVLCIFIYILDSADNFLQKKKAG
360 370 380 390 400 410
330 340 350 360
pF1KB6 LCLVSEIPPKGGALGEGPGASPCNQHSPYWAPPCYTLKPET
XP_011 SSETEIEVICYIEKPGVETLEDSVF
420 430
>>XP_011531979 (OMIM: 147851) PREDICTED: interleukin-5 r (439 aa)
initn: 165 init1: 117 opt: 222 Z-score: 248.1 bits: 54.8 E(85289): 4.4e-07
Smith-Waterman score: 222; 23.7% identity (58.5% similar) in 241 aa overlap (70-299:153-385)
40 50 60 70 80 90
pF1KB6 FFLTTMPTDSLSVSTLPLPEVQCFVFNVEYMNCTWNSSSE-PQPTNLTLHYWYKNSDNDK
..::: ... :. :. :.: : .: ...
XP_011 GSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGTDAPEDTQYFLYYRY-GSWTEE
130 140 150 160 170 180
100 110 120 130 140 150
pF1KB6 VQKCSHYLFSEEITSGCQLQKKEI----HLYQTFVVQLQDPREPRRQATQMLKLQNLVIP
:. :. ....:. : . . : . . . .:. .. . : :.. :. .
XP_011 CQEYSKDTLGRNIA--CWFPRTFILSKGRDWLAVLVNGSSKHSAIRPFDQLFALHAIDQI
190 200 210 220 230
160 170 180 190 200 210
pF1KB6 WAPENLTLHKLSESQLELNWN---NRFLNHCLEHLVQYRTDWDHSWTEQSVDYRHKFSLP
: :.: .. ..: ..:. . : ::... :. . . ... . . . : .
XP_011 NPPLNVTA-EIEGTRLSIQWEKPVSAFPIHCFDYEVKIH-NTRNGYLQIEKLMTNAF-IS
240 250 260 270 280 290
220 230 240 250 260 270
pF1KB6 SVDGQKRYTFRVRSRFNPLCGSAQHWSEWSHPIHWGSNTSKENPFLFALEAVVISVGSMG
.: ..: .::. . .: : :::::.::. :.. : :.. ... .. .
XP_011 IIDDLSKYDVQVRAAVSSMCREAGLWSEWSQPIYVGNDEHKPLREWFVI-VIMATICFIL
300 310 320 330 340 350
280 290 300 310 320
pF1KB6 LIISLLC--VYFWLERTMPRIPTLK-NLEDLVTEYHGNFSAWSGVSKGLAESLQPDYSER
::.::.: ..:. . .: ::. : :..::
XP_011 LILSLICKICHLWI-KLFPPIPAPKSNIKDLFVTTNYEVLCIFIYILDSADNFLQKKKAG
360 370 380 390 400 410
330 340 350 360
pF1KB6 LCLVSEIPPKGGALGEGPGASPCNQHSPYWAPPCYTLKPET
XP_011 SSETEIEVICYIEKPGVETLEDSVF
420 430
>>XP_005261397 (OMIM: 138981,614370) PREDICTED: cytokine (903 aa)
initn: 121 init1: 58 opt: 222 Z-score: 243.6 bits: 55.0 E(85289): 7.8e-07
Smith-Waterman score: 222; 26.8% identity (56.3% similar) in 254 aa overlap (60-291:248-485)
30 40 50 60 70 80
pF1KB6 PNGNEDTTADFFLTTMPTDSLSVSTLPLPEVQCFVFNVEYMNCTWNSSSEPQPTNLTLHY
..:: .. ..:.:. .: .....
XP_005 PGSRLSGRPSKWSPEVCWDSQPGDEAQPQNLECFFDGAAVLSCSWEVRKEVA-SSVSFGL
220 230 240 250 260 270
90 100 110 120 130
pF1KB6 WYKNSDND------KVQKCSHYLF----SEEITSGCQLQKKEIHLYQTFVVQLQDPREPR
.:: : . . ..:: : : . ::. . . ..:..: ::
XP_005 FYKPSPDAGSAVLLREEECSPVLREGLGSLHTRHHCQIPVPDPATHGQYIVSVQ----PR
280 290 300 310 320 330
140 150 160 170 180 190
pF1KB6 RQATQMLKLQNLVIPWAPENLTLHKLSESQLELNWNN---RF--LNHCLEHLVQYRTD--
: : . .: ... : :: .:.. : ..: : :.. :. ..: .: .::: :
XP_005 R-AEKHIK-SSVNIQMAPPSLNVTKDGDSY-SLRWETMKMRYEHIDHTFE--IQYRKDTA
340 350 360 370 380
200 210 220 230 240 250
pF1KB6 -WDHSWTEQSVDYRHKFSLPSVDGQKRYTFRVRSRFNPLCGSAQHWSEWSHPIHWGSNTS
: : :: ... :...::... . :: ::: : . : :::::. : .:
XP_005 TWKDSKTE-TLQNAHSMALPALEPSTRYWARVRVRTSRT-GYNGIWSEWSEARSW--DTE
390 400 410 420 430 440
260 270 280 290 300
pF1KB6 KENPFLFALEAVVISVGSMGLIISL-LC-VY-FWLERTMP-RIPTLKNLEDLVTEYHGNF
. : ...: .:: . .......: .: .: . :.: .::
XP_005 SVLP-MWVLALIVIFL-TIAVLLALRFCGIYGYRLRRKWEEKIPNPSKSHLFQNGSAELW
450 460 470 480 490 500
310 320 330 340 350 360
pF1KB6 SAWSGVSKGLAESLQPDYSERLCLVSEIPPKGGALGEGPGASPCNQHSPYWAPPCYTLKP
XP_005 PPGSMSAFTSGSPPHQGPWGSRFPELEGVFPVGFGDSEVSPLTIEDPKHVCDPPSGPDTT
510 520 530 540 550 560
369 residues in 1 query sequences
60827320 residues in 85289 library sequences
Tcomplib [36.3.4 Apr, 2011] (8 proc)
start: Sat Nov 5 01:18:03 2016 done: Sat Nov 5 01:18:05 2016
Total Scan time: 8.650 Total Display time: 0.030
Function used was FASTA [36.3.4 Apr, 2011]