FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6543, 369 aa 1>>>pF1KB6543 369 - 369 aa - 369 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 5.5879+/-0.000328; mu= 15.7347+/- 0.020 mean_var=82.8828+/-16.836, 0's: 0 Z-trim(116.3): 111 B-trim: 0 in 0/54 Lambda= 0.140878 statistics sampled from 27334 (27448) to 27334 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.693), E-opt: 0.2 (0.322), width: 16 Scan time: 8.650 The best scores are: opt bits E(85289) NP_000197 (OMIM: 300400,308380,312863) cytokine re ( 369) 2581 534.2 1.8e-151 NP_000631 (OMIM: 300130) interleukin-13 receptor s ( 380) 316 73.8 7e-13 XP_011528206 (OMIM: 138981,614370) PREDICTED: cyto ( 909) 249 60.5 1.8e-08 NP_000386 (OMIM: 138981,614370) cytokine receptor ( 897) 239 58.5 7.1e-08 XP_011528205 (OMIM: 138981,614370) PREDICTED: cyto ( 915) 232 57.0 1.9e-07 NP_000555 (OMIM: 147851) interleukin-5 receptor su ( 420) 222 54.8 4.3e-07 NP_783853 (OMIM: 147851) interleukin-5 receptor su ( 420) 222 54.8 4.3e-07 XP_011531980 (OMIM: 147851) PREDICTED: interleukin ( 439) 222 54.8 4.4e-07 XP_011531979 (OMIM: 147851) PREDICTED: interleukin ( 439) 222 54.8 4.4e-07 XP_005261397 (OMIM: 138981,614370) PREDICTED: cyto ( 903) 222 55.0 7.8e-07 XP_011544472 (OMIM: 306250,425000) PREDICTED: gran ( 383) 200 50.3 8.9e-06 XP_016884776 (OMIM: 306250,425000) PREDICTED: gran ( 383) 200 50.3 8.9e-06 XP_011543925 (OMIM: 306250,425000) PREDICTED: gran ( 383) 200 50.3 8.9e-06 XP_016885517 (OMIM: 306250,425000) PREDICTED: gran ( 383) 200 50.3 8.9e-06 XP_011543924 (OMIM: 306250,425000) PREDICTED: gran ( 385) 200 50.3 8.9e-06 XP_011544471 (OMIM: 306250,425000) PREDICTED: gran ( 385) 200 50.3 8.9e-06 XP_011543923 (OMIM: 306250,425000) PREDICTED: gran ( 386) 200 50.3 8.9e-06 XP_011544470 (OMIM: 306250,425000) PREDICTED: gran ( 386) 200 50.3 8.9e-06 XP_011543922 (OMIM: 306250,425000) PREDICTED: gran ( 389) 200 50.3 9e-06 XP_011544469 (OMIM: 306250,425000) PREDICTED: gran ( 389) 200 50.3 9e-06 XP_011544468 (OMIM: 306250,425000) PREDICTED: gran ( 400) 200 50.3 9.2e-06 NP_001155001 (OMIM: 306250,425000) granulocyte-mac ( 400) 200 50.3 9.2e-06 NP_006131 (OMIM: 306250,425000) granulocyte-macrop ( 400) 200 50.3 9.2e-06 NP_758448 (OMIM: 306250,425000) granulocyte-macrop ( 400) 200 50.3 9.2e-06 XP_011543921 (OMIM: 306250,425000) PREDICTED: gran ( 400) 200 50.3 9.2e-06 XP_011544467 (OMIM: 306250,425000) PREDICTED: gran ( 410) 200 50.3 9.4e-06 XP_011543920 (OMIM: 306250,425000) PREDICTED: gran ( 410) 200 50.3 9.4e-06 NP_001155003 (OMIM: 306250,425000) granulocyte-mac ( 410) 200 50.3 9.4e-06 NP_000112 (OMIM: 133100,133171) erythropoietin rec ( 508) 198 50.0 1.5e-05 NP_001230028 (OMIM: 147851) interleukin-5 receptor ( 378) 192 48.6 2.7e-05 XP_011544483 (OMIM: 300357,400023) PREDICTED: cyto ( 370) 190 48.2 3.5e-05 XP_011543936 (OMIM: 300357,400023) PREDICTED: cyto ( 370) 190 48.2 3.5e-05 NP_071431 (OMIM: 300357,400023) cytokine receptor- ( 371) 190 48.2 3.5e-05 NP_001551 (OMIM: 300119) interleukin-13 receptor s ( 427) 189 48.1 4.5e-05 XP_011529638 (OMIM: 300119) PREDICTED: interleukin ( 529) 189 48.1 5.4e-05 NP_001155004 (OMIM: 306250,425000) granulocyte-mac ( 267) 180 46.1 0.00011 NP_001155002 (OMIM: 306250,425000) granulocyte-mac ( 434) 165 43.2 0.0014 XP_016885518 (OMIM: 306250,425000) PREDICTED: gran ( 333) 162 42.5 0.0017 NP_758450 (OMIM: 306250,425000) granulocyte-macrop ( 333) 162 42.5 0.0017 XP_011544475 (OMIM: 306250,425000) PREDICTED: gran ( 333) 162 42.5 0.0017 XP_011544476 (OMIM: 306250,425000) PREDICTED: gran ( 333) 162 42.5 0.0017 XP_011543930 (OMIM: 306250,425000) PREDICTED: gran ( 333) 162 42.5 0.0017 XP_016884777 (OMIM: 306250,425000) PREDICTED: gran ( 333) 162 42.5 0.0017 XP_011544477 (OMIM: 306250,425000) PREDICTED: gran ( 333) 162 42.5 0.0017 XP_011543928 (OMIM: 306250,425000) PREDICTED: gran ( 333) 162 42.5 0.0017 XP_011543929 (OMIM: 306250,425000) PREDICTED: gran ( 333) 162 42.5 0.0017 NP_783851 (OMIM: 147851) interleukin-5 receptor su ( 333) 161 42.3 0.0019 NP_783854 (OMIM: 147851) interleukin-5 receptor su ( 333) 161 42.3 0.0019 NP_783855 (OMIM: 147851) interleukin-5 receptor su ( 335) 161 42.3 0.0019 NP_783852 (OMIM: 147851) interleukin-5 receptor su ( 335) 161 42.3 0.0019 >>NP_000197 (OMIM: 300400,308380,312863) cytokine recept (369 aa) initn: 2581 init1: 2581 opt: 2581 Z-score: 2840.3 bits: 534.2 E(85289): 1.8e-151 Smith-Waterman score: 2581; 100.0% identity (100.0% similar) in 369 aa overlap (1-369:1-369) 10 20 30 40 50 60 pF1KB6 MLKPSLPFTSLLFLQLPLLGVGLNTTILTPNGNEDTTADFFLTTMPTDSLSVSTLPLPEV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 MLKPSLPFTSLLFLQLPLLGVGLNTTILTPNGNEDTTADFFLTTMPTDSLSVSTLPLPEV 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 QCFVFNVEYMNCTWNSSSEPQPTNLTLHYWYKNSDNDKVQKCSHYLFSEEITSGCQLQKK :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 QCFVFNVEYMNCTWNSSSEPQPTNLTLHYWYKNSDNDKVQKCSHYLFSEEITSGCQLQKK 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 EIHLYQTFVVQLQDPREPRRQATQMLKLQNLVIPWAPENLTLHKLSESQLELNWNNRFLN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 EIHLYQTFVVQLQDPREPRRQATQMLKLQNLVIPWAPENLTLHKLSESQLELNWNNRFLN 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 HCLEHLVQYRTDWDHSWTEQSVDYRHKFSLPSVDGQKRYTFRVRSRFNPLCGSAQHWSEW :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 HCLEHLVQYRTDWDHSWTEQSVDYRHKFSLPSVDGQKRYTFRVRSRFNPLCGSAQHWSEW 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 SHPIHWGSNTSKENPFLFALEAVVISVGSMGLIISLLCVYFWLERTMPRIPTLKNLEDLV :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 SHPIHWGSNTSKENPFLFALEAVVISVGSMGLIISLLCVYFWLERTMPRIPTLKNLEDLV 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 TEYHGNFSAWSGVSKGLAESLQPDYSERLCLVSEIPPKGGALGEGPGASPCNQHSPYWAP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_000 TEYHGNFSAWSGVSKGLAESLQPDYSERLCLVSEIPPKGGALGEGPGASPCNQHSPYWAP 310 320 330 340 350 360 pF1KB6 PCYTLKPET ::::::::: NP_000 PCYTLKPET >>NP_000631 (OMIM: 300130) interleukin-13 receptor subun (380 aa) initn: 189 init1: 97 opt: 316 Z-score: 352.2 bits: 73.8 E(85289): 7e-13 Smith-Waterman score: 316; 25.9% identity (56.6% similar) in 251 aa overlap (31-268:115-360) 10 20 30 40 50 60 pF1KB6 MLKPSLPFTSLLFLQLPLLGVGLNTTILTPNGNEDTTADFFLTTMPTDSLSVSTLPLPEV ::.: . ... ::. . .. . .. NP_000 ITKNLHYKDGFDLNKGIEAKIHTLLPWQCTNGSE-VQSSWAETTYWISPQGIPETKVQDM 90 100 110 120 130 140 70 80 90 100 110 pF1KB6 QCFVFNVEYMNCTWNSS-SEPQPTNLTLHYWYKNSDNDKVQKCSHYLFSEEITSGCQLQK .: .: .:. :.:. . . :: .: :::.. :. . .: :. .. . ::.. NP_000 DCVYYNWQYLLCSWKPGIGVLLDTNYNLFYWYEGLDH--ALQCVDYIKADGQNIGCRFPY 150 160 170 180 190 200 120 130 140 150 160 170 pF1KB6 KEIHLYQTFVVQLQDPRE--PRRQATQMLKLQNLVIPWAPENLTLHKLSESQLELNWN-- : :. : . .. : : :.. ..:::.: : : ::. . : ...:.:. NP_000 LEASDYKDFYICVNGSSENKPIRSSYFTFQLQNIVKPLPPVYLTFTRESSCEIKLKWSIP 210 220 230 240 250 260 180 190 200 210 220 230 pF1KB6 -NRFLNHCLEHLVQYRTDWDHSWTEQSVDYRHKFSLPSVDGQKRYTFRVRSRFNPLCGSA . . .:... .. : : : . . .:. . ..: ... .. : :::. : :.. NP_000 LGPIPARCFDYEIEIRED-DTTLVTATVE-NETYTLKTTNETRQLCFVVRSKVNIYCSDD 270 280 290 300 310 240 250 260 270 280 pF1KB6 QHWSEWSHPIHW-GSNTSKEN------PFLFALEAVVISVGSMGLIISLLCVYFWLERTM ::::: : : . ::.. :: : : :.. .: NP_000 GIWSEWSDKQCWEGEDLSKKTLLRFWLPFGFILILVIFVTGLLLRKPNTYPKMIPEFFCD 320 330 340 350 360 370 290 300 310 320 330 340 pF1KB6 PRIPTLKNLEDLVTEYHGNFSAWSGVSKGLAESLQPDYSERLCLVSEIPPKGGALGEGPG NP_000 T 380 >>XP_011528206 (OMIM: 138981,614370) PREDICTED: cytokine (909 aa) initn: 121 init1: 61 opt: 249 Z-score: 273.2 bits: 60.5 E(85289): 1.8e-08 Smith-Waterman score: 249; 26.7% identity (52.4% similar) in 296 aa overlap (60-343:248-527) 30 40 50 60 70 80 pF1KB6 PNGNEDTTADFFLTTMPTDSLSVSTLPLPEVQCFVFNVEYMNCTWNSSSEPQPTNLTLHY ..:: .. ..:.:. .: ..... XP_011 PGSRLSGRPSKWSPEVCWDSQPGDEAQPQNLECFFDGAAVLSCSWEVRKEVA-SSVSFGL 220 230 240 250 260 270 90 100 110 120 130 140 pF1KB6 WYKNSDNDKVQKCSHYLF----SEEITSGCQLQKKEIHLYQTFVVQLQDPREPRRQATQM .:: : . ..:: : : . ::. . . ..:..: ::: : . XP_011 FYKPSPDAGEEECSPVLREGLGSLHTRHHCQIPVPDPATHGQYIVSVQ----PRR-AEKH 280 290 300 310 320 330 150 160 170 180 190 pF1KB6 LKLQNLVIPWAPENLTLHKLSESQLELNWNN---RF--LNHCLEHLVQYRTD---WDHSW .: ... : :: .:.. : ..: : :.. :. ..: .: .::: : : : XP_011 IK-SSVNIQMAPPSLNVTKDGDSY-SLRWETMKMRYEHIDHTFE--IQYRKDTATWKDSK 340 350 360 370 380 200 210 220 230 240 250 pF1KB6 TEQSVDYRHKFSLPSVDGQKRYTFRVRSRFNPLCGSAQHWSEWSHPIHWGSNTSKENPFL :: ... :...::... . :: ::: : . : :::::. : .... . :. XP_011 TE-TLQNAHSMALPALEPSTRYWARVRVR-TSRTGYNGIWSEWSEARSWDTESDADIPLS 390 400 410 420 430 440 260 270 280 290 300 310 pF1KB6 FALEAVVISVGSMGLIISLLCVYFWLERTMPRIPTLKNLEDLVTEYHGNFSAWSGVSKGL : : . . ..::. .: . : . : . :. : : : ..: XP_011 PRLLEV-LPMWVLALIVIFLTIAVLLALRFCGIYGYR-LRRKWEEKIPNPSKSHLFQNGS 450 460 470 480 490 500 320 330 340 350 360 pF1KB6 AESLQPDYSERLCLVSEIPPKGGALGEGPGASPCNQHSPYWAPPCYTLKPET :: : : : ..: ::. : : XP_011 AE-LWPPGSMS-AFTSGSPPHQGPWGSRFPELEGVFPVGFGDSEVSPLTIEDPKHVCDPP 510 520 530 540 550 560 >>NP_000386 (OMIM: 138981,614370) cytokine receptor comm (897 aa) initn: 121 init1: 58 opt: 239 Z-score: 262.3 bits: 58.5 E(85289): 7.1e-08 Smith-Waterman score: 239; 27.4% identity (57.3% similar) in 248 aa overlap (60-291:248-479) 30 40 50 60 70 80 pF1KB6 PNGNEDTTADFFLTTMPTDSLSVSTLPLPEVQCFVFNVEYMNCTWNSSSEPQPTNLTLHY ..:: .. ..:.:. .: ..... NP_000 PGSRLSGRPSKWSPEVCWDSQPGDEAQPQNLECFFDGAAVLSCSWEVRKEVA-SSVSFGL 220 230 240 250 260 270 90 100 110 120 130 140 pF1KB6 WYKNSDNDKVQKCSHYLF----SEEITSGCQLQKKEIHLYQTFVVQLQDPREPRRQATQM .:: : . ..:: : : . ::. . . ..:..: ::: : . NP_000 FYKPSPDAGEEECSPVLREGLGSLHTRHHCQIPVPDPATHGQYIVSVQ----PRR-AEKH 280 290 300 310 320 330 150 160 170 180 190 pF1KB6 LKLQNLVIPWAPENLTLHKLSESQLELNWNN---RF--LNHCLEHLVQYRTD---WDHSW .: ... : :: .:.. : ..: : :.. :. ..: .: .::: : : : NP_000 IK-SSVNIQMAPPSLNVTKDGDSY-SLRWETMKMRYEHIDHTFE--IQYRKDTATWKDSK 340 350 360 370 380 200 210 220 230 240 250 pF1KB6 TEQSVDYRHKFSLPSVDGQKRYTFRVRSRFNPLCGSAQHWSEWSHPIHWGSNTSKENPFL :: ... :...::... . :: ::: : . : :::::. : .: . : . NP_000 TE-TLQNAHSMALPALEPSTRYWARVRVRTSRT-GYNGIWSEWSEARSW--DTESVLP-M 390 400 410 420 430 440 260 270 280 290 300 310 pF1KB6 FALEAVVISVGSMGLIISL-LC-VY-FWLERTMP-RIPTLKNLEDLVTEYHGNFSAWSGV ..: .:: . .......: .: .: . :.: .:: NP_000 WVLALIVIFL-TIAVLLALRFCGIYGYRLRRKWEEKIPNPSKSHLFQNGSAELWPPGSMS 450 460 470 480 490 500 320 330 340 350 360 pF1KB6 SKGLAESLQPDYSERLCLVSEIPPKGGALGEGPGASPCNQHSPYWAPPCYTLKPET NP_000 AFTSGSPPHQGPWGSRFPELEGVFPVGFGDSEVSPLTIEDPKHVCDPPSGPDTTPAASDL 510 520 530 540 550 560 >>XP_011528205 (OMIM: 138981,614370) PREDICTED: cytokine (915 aa) initn: 121 init1: 61 opt: 232 Z-score: 254.5 bits: 57.0 E(85289): 1.9e-07 Smith-Waterman score: 232; 26.2% identity (51.7% similar) in 302 aa overlap (60-343:248-533) 30 40 50 60 70 80 pF1KB6 PNGNEDTTADFFLTTMPTDSLSVSTLPLPEVQCFVFNVEYMNCTWNSSSEPQPTNLTLHY ..:: .. ..:.:. .: ..... XP_011 PGSRLSGRPSKWSPEVCWDSQPGDEAQPQNLECFFDGAAVLSCSWEVRKEVA-SSVSFGL 220 230 240 250 260 270 90 100 110 120 130 pF1KB6 WYKNSDND------KVQKCSHYLF----SEEITSGCQLQKKEIHLYQTFVVQLQDPREPR .:: : . . ..:: : : . ::. . . ..:..: :: XP_011 FYKPSPDAGSAVLLREEECSPVLREGLGSLHTRHHCQIPVPDPATHGQYIVSVQ----PR 280 290 300 310 320 330 140 150 160 170 180 190 pF1KB6 RQATQMLKLQNLVIPWAPENLTLHKLSESQLELNWNN---RF--LNHCLEHLVQYRTD-- : : . .: ... : :: .:.. : ..: : :.. :. ..: .: .::: : XP_011 R-AEKHIK-SSVNIQMAPPSLNVTKDGDSY-SLRWETMKMRYEHIDHTFE--IQYRKDTA 340 350 360 370 380 200 210 220 230 240 250 pF1KB6 -WDHSWTEQSVDYRHKFSLPSVDGQKRYTFRVRSRFNPLCGSAQHWSEWSHPIHWGSNTS : : :: ... :...::... . :: ::: : . : :::::. : .... XP_011 TWKDSKTE-TLQNAHSMALPALEPSTRYWARVRVR-TSRTGYNGIWSEWSEARSWDTESD 390 400 410 420 430 440 260 270 280 290 300 310 pF1KB6 KENPFLFALEAVVISVGSMGLIISLLCVYFWLERTMPRIPTLKNLEDLVTEYHGNFSAWS . :. : : . . ..::. .: . : . : . :. : : : XP_011 ADIPLSPRLLEV-LPMWVLALIVIFLTIAVLLALRFCGIYGYR-LRRKWEEKIPNPSKSH 450 460 470 480 490 500 320 330 340 350 360 pF1KB6 GVSKGLAESLQPDYSERLCLVSEIPPKGGALGEGPGASPCNQHSPYWAPPCYTLKPET ..: :: : : : ..: ::. : : XP_011 LFQNGSAE-LWPPGSMS-AFTSGSPPHQGPWGSRFPELEGVFPVGFGDSEVSPLTIEDPK 510 520 530 540 550 560 XP_011 HVCDPPSGPDTTPAASDLPTEQPPSPQPGPPAASHTPEKQASSFDFNGPYLGPPHSRSLP 570 580 590 600 610 620 >>NP_000555 (OMIM: 147851) interleukin-5 receptor subuni (420 aa) initn: 165 init1: 117 opt: 222 Z-score: 248.3 bits: 54.8 E(85289): 4.3e-07 Smith-Waterman score: 222; 23.7% identity (58.5% similar) in 241 aa overlap (70-299:153-385) 40 50 60 70 80 90 pF1KB6 FFLTTMPTDSLSVSTLPLPEVQCFVFNVEYMNCTWNSSSE-PQPTNLTLHYWYKNSDNDK ..::: ... :. :. :.: : .: ... NP_000 GSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGTDAPEDTQYFLYYRY-GSWTEE 130 140 150 160 170 180 100 110 120 130 140 150 pF1KB6 VQKCSHYLFSEEITSGCQLQKKEI----HLYQTFVVQLQDPREPRRQATQMLKLQNLVIP :. :. ....:. : . . : . . . .:. .. . : :.. :. . NP_000 CQEYSKDTLGRNIA--CWFPRTFILSKGRDWLAVLVNGSSKHSAIRPFDQLFALHAIDQI 190 200 210 220 230 160 170 180 190 200 210 pF1KB6 WAPENLTLHKLSESQLELNWN---NRFLNHCLEHLVQYRTDWDHSWTEQSVDYRHKFSLP : :.: .. ..: ..:. . : ::... :. . . ... . . . : . NP_000 NPPLNVTA-EIEGTRLSIQWEKPVSAFPIHCFDYEVKIH-NTRNGYLQIEKLMTNAF-IS 240 250 260 270 280 290 220 230 240 250 260 270 pF1KB6 SVDGQKRYTFRVRSRFNPLCGSAQHWSEWSHPIHWGSNTSKENPFLFALEAVVISVGSMG .: ..: .::. . .: : :::::.::. :.. : :.. ... .. . NP_000 IIDDLSKYDVQVRAAVSSMCREAGLWSEWSQPIYVGNDEHKPLREWFVI-VIMATICFIL 300 310 320 330 340 350 280 290 300 310 320 pF1KB6 LIISLLC--VYFWLERTMPRIPTLK-NLEDLVTEYHGNFSAWSGVSKGLAESLQPDYSER ::.::.: ..:. . .: ::. : :..:: NP_000 LILSLICKICHLWI-KLFPPIPAPKSNIKDLFVTTNYEKAGSSETEIEVICYIEKPGVET 360 370 380 390 400 410 330 340 350 360 pF1KB6 LCLVSEIPPKGGALGEGPGASPCNQHSPYWAPPCYTLKPET NP_000 LEDSVF 420 >>NP_783853 (OMIM: 147851) interleukin-5 receptor subuni (420 aa) initn: 165 init1: 117 opt: 222 Z-score: 248.3 bits: 54.8 E(85289): 4.3e-07 Smith-Waterman score: 222; 23.7% identity (58.5% similar) in 241 aa overlap (70-299:153-385) 40 50 60 70 80 90 pF1KB6 FFLTTMPTDSLSVSTLPLPEVQCFVFNVEYMNCTWNSSSE-PQPTNLTLHYWYKNSDNDK ..::: ... :. :. :.: : .: ... NP_783 GSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGTDAPEDTQYFLYYRY-GSWTEE 130 140 150 160 170 180 100 110 120 130 140 150 pF1KB6 VQKCSHYLFSEEITSGCQLQKKEI----HLYQTFVVQLQDPREPRRQATQMLKLQNLVIP :. :. ....:. : . . : . . . .:. .. . : :.. :. . NP_783 CQEYSKDTLGRNIA--CWFPRTFILSKGRDWLAVLVNGSSKHSAIRPFDQLFALHAIDQI 190 200 210 220 230 160 170 180 190 200 210 pF1KB6 WAPENLTLHKLSESQLELNWN---NRFLNHCLEHLVQYRTDWDHSWTEQSVDYRHKFSLP : :.: .. ..: ..:. . : ::... :. . . ... . . . : . NP_783 NPPLNVTA-EIEGTRLSIQWEKPVSAFPIHCFDYEVKIH-NTRNGYLQIEKLMTNAF-IS 240 250 260 270 280 290 220 230 240 250 260 270 pF1KB6 SVDGQKRYTFRVRSRFNPLCGSAQHWSEWSHPIHWGSNTSKENPFLFALEAVVISVGSMG .: ..: .::. . .: : :::::.::. :.. : :.. ... .. . NP_783 IIDDLSKYDVQVRAAVSSMCREAGLWSEWSQPIYVGNDEHKPLREWFVI-VIMATICFIL 300 310 320 330 340 350 280 290 300 310 320 pF1KB6 LIISLLC--VYFWLERTMPRIPTLK-NLEDLVTEYHGNFSAWSGVSKGLAESLQPDYSER ::.::.: ..:. . .: ::. : :..:: NP_783 LILSLICKICHLWI-KLFPPIPAPKSNIKDLFVTTNYEKAGSSETEIEVICYIEKPGVET 360 370 380 390 400 410 330 340 350 360 pF1KB6 LCLVSEIPPKGGALGEGPGASPCNQHSPYWAPPCYTLKPET NP_783 LEDSVF 420 >>XP_011531980 (OMIM: 147851) PREDICTED: interleukin-5 r (439 aa) initn: 165 init1: 117 opt: 222 Z-score: 248.1 bits: 54.8 E(85289): 4.4e-07 Smith-Waterman score: 222; 23.7% identity (58.5% similar) in 241 aa overlap (70-299:153-385) 40 50 60 70 80 90 pF1KB6 FFLTTMPTDSLSVSTLPLPEVQCFVFNVEYMNCTWNSSSE-PQPTNLTLHYWYKNSDNDK ..::: ... :. :. :.: : .: ... XP_011 GSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGTDAPEDTQYFLYYRY-GSWTEE 130 140 150 160 170 180 100 110 120 130 140 150 pF1KB6 VQKCSHYLFSEEITSGCQLQKKEI----HLYQTFVVQLQDPREPRRQATQMLKLQNLVIP :. :. ....:. : . . : . . . .:. .. . : :.. :. . XP_011 CQEYSKDTLGRNIA--CWFPRTFILSKGRDWLAVLVNGSSKHSAIRPFDQLFALHAIDQI 190 200 210 220 230 160 170 180 190 200 210 pF1KB6 WAPENLTLHKLSESQLELNWN---NRFLNHCLEHLVQYRTDWDHSWTEQSVDYRHKFSLP : :.: .. ..: ..:. . : ::... :. . . ... . . . : . XP_011 NPPLNVTA-EIEGTRLSIQWEKPVSAFPIHCFDYEVKIH-NTRNGYLQIEKLMTNAF-IS 240 250 260 270 280 290 220 230 240 250 260 270 pF1KB6 SVDGQKRYTFRVRSRFNPLCGSAQHWSEWSHPIHWGSNTSKENPFLFALEAVVISVGSMG .: ..: .::. . .: : :::::.::. :.. : :.. ... .. . XP_011 IIDDLSKYDVQVRAAVSSMCREAGLWSEWSQPIYVGNDEHKPLREWFVI-VIMATICFIL 300 310 320 330 340 350 280 290 300 310 320 pF1KB6 LIISLLC--VYFWLERTMPRIPTLK-NLEDLVTEYHGNFSAWSGVSKGLAESLQPDYSER ::.::.: ..:. . .: ::. : :..:: XP_011 LILSLICKICHLWI-KLFPPIPAPKSNIKDLFVTTNYEVLCIFIYILDSADNFLQKKKAG 360 370 380 390 400 410 330 340 350 360 pF1KB6 LCLVSEIPPKGGALGEGPGASPCNQHSPYWAPPCYTLKPET XP_011 SSETEIEVICYIEKPGVETLEDSVF 420 430 >>XP_011531979 (OMIM: 147851) PREDICTED: interleukin-5 r (439 aa) initn: 165 init1: 117 opt: 222 Z-score: 248.1 bits: 54.8 E(85289): 4.4e-07 Smith-Waterman score: 222; 23.7% identity (58.5% similar) in 241 aa overlap (70-299:153-385) 40 50 60 70 80 90 pF1KB6 FFLTTMPTDSLSVSTLPLPEVQCFVFNVEYMNCTWNSSSE-PQPTNLTLHYWYKNSDNDK ..::: ... :. :. :.: : .: ... XP_011 GSPGTSIVNLTCTTNTTEDNYSRLRSYQVSLHCTWLVGTDAPEDTQYFLYYRY-GSWTEE 130 140 150 160 170 180 100 110 120 130 140 150 pF1KB6 VQKCSHYLFSEEITSGCQLQKKEI----HLYQTFVVQLQDPREPRRQATQMLKLQNLVIP :. :. ....:. : . . : . . . .:. .. . : :.. :. . XP_011 CQEYSKDTLGRNIA--CWFPRTFILSKGRDWLAVLVNGSSKHSAIRPFDQLFALHAIDQI 190 200 210 220 230 160 170 180 190 200 210 pF1KB6 WAPENLTLHKLSESQLELNWN---NRFLNHCLEHLVQYRTDWDHSWTEQSVDYRHKFSLP : :.: .. ..: ..:. . : ::... :. . . ... . . . : . XP_011 NPPLNVTA-EIEGTRLSIQWEKPVSAFPIHCFDYEVKIH-NTRNGYLQIEKLMTNAF-IS 240 250 260 270 280 290 220 230 240 250 260 270 pF1KB6 SVDGQKRYTFRVRSRFNPLCGSAQHWSEWSHPIHWGSNTSKENPFLFALEAVVISVGSMG .: ..: .::. . .: : :::::.::. :.. : :.. ... .. . XP_011 IIDDLSKYDVQVRAAVSSMCREAGLWSEWSQPIYVGNDEHKPLREWFVI-VIMATICFIL 300 310 320 330 340 350 280 290 300 310 320 pF1KB6 LIISLLC--VYFWLERTMPRIPTLK-NLEDLVTEYHGNFSAWSGVSKGLAESLQPDYSER ::.::.: ..:. . .: ::. : :..:: XP_011 LILSLICKICHLWI-KLFPPIPAPKSNIKDLFVTTNYEVLCIFIYILDSADNFLQKKKAG 360 370 380 390 400 410 330 340 350 360 pF1KB6 LCLVSEIPPKGGALGEGPGASPCNQHSPYWAPPCYTLKPET XP_011 SSETEIEVICYIEKPGVETLEDSVF 420 430 >>XP_005261397 (OMIM: 138981,614370) PREDICTED: cytokine (903 aa) initn: 121 init1: 58 opt: 222 Z-score: 243.6 bits: 55.0 E(85289): 7.8e-07 Smith-Waterman score: 222; 26.8% identity (56.3% similar) in 254 aa overlap (60-291:248-485) 30 40 50 60 70 80 pF1KB6 PNGNEDTTADFFLTTMPTDSLSVSTLPLPEVQCFVFNVEYMNCTWNSSSEPQPTNLTLHY ..:: .. ..:.:. .: ..... XP_005 PGSRLSGRPSKWSPEVCWDSQPGDEAQPQNLECFFDGAAVLSCSWEVRKEVA-SSVSFGL 220 230 240 250 260 270 90 100 110 120 130 pF1KB6 WYKNSDND------KVQKCSHYLF----SEEITSGCQLQKKEIHLYQTFVVQLQDPREPR .:: : . . ..:: : : . ::. . . ..:..: :: XP_005 FYKPSPDAGSAVLLREEECSPVLREGLGSLHTRHHCQIPVPDPATHGQYIVSVQ----PR 280 290 300 310 320 330 140 150 160 170 180 190 pF1KB6 RQATQMLKLQNLVIPWAPENLTLHKLSESQLELNWNN---RF--LNHCLEHLVQYRTD-- : : . .: ... : :: .:.. : ..: : :.. :. ..: .: .::: : XP_005 R-AEKHIK-SSVNIQMAPPSLNVTKDGDSY-SLRWETMKMRYEHIDHTFE--IQYRKDTA 340 350 360 370 380 200 210 220 230 240 250 pF1KB6 -WDHSWTEQSVDYRHKFSLPSVDGQKRYTFRVRSRFNPLCGSAQHWSEWSHPIHWGSNTS : : :: ... :...::... . :: ::: : . : :::::. : .: XP_005 TWKDSKTE-TLQNAHSMALPALEPSTRYWARVRVRTSRT-GYNGIWSEWSEARSW--DTE 390 400 410 420 430 440 260 270 280 290 300 pF1KB6 KENPFLFALEAVVISVGSMGLIISL-LC-VY-FWLERTMP-RIPTLKNLEDLVTEYHGNF . : ...: .:: . .......: .: .: . :.: .:: XP_005 SVLP-MWVLALIVIFL-TIAVLLALRFCGIYGYRLRRKWEEKIPNPSKSHLFQNGSAELW 450 460 470 480 490 500 310 320 330 340 350 360 pF1KB6 SAWSGVSKGLAESLQPDYSERLCLVSEIPPKGGALGEGPGASPCNQHSPYWAPPCYTLKP XP_005 PPGSMSAFTSGSPPHQGPWGSRFPELEGVFPVGFGDSEVSPLTIEDPKHVCDPPSGPDTT 510 520 530 540 550 560 369 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 01:18:03 2016 done: Sat Nov 5 01:18:05 2016 Total Scan time: 8.650 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]