FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6546, 392 aa 1>>>pF1KB6546 392 - 392 aa - 392 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.7581+/-0.000392; mu= 5.7610+/- 0.024 mean_var=171.9058+/-35.394, 0's: 0 Z-trim(117.2): 61 B-trim: 277 in 2/49 Lambda= 0.097820 statistics sampled from 28985 (29046) to 28985 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.705), E-opt: 0.2 (0.341), width: 16 Scan time: 8.530 The best scores are: opt bits E(85289) NP_071906 (OMIM: 609916) 5-azacytidine-induced pro ( 392) 2586 377.2 3.7e-104 XP_005265449 (OMIM: 609916) PREDICTED: 5-azacytidi ( 392) 2586 377.2 3.7e-104 XP_011532311 (OMIM: 609916) PREDICTED: 5-azacytidi ( 395) 2586 377.2 3.7e-104 NP_001258579 (OMIM: 609916) 5-azacytidine-induced ( 280) 1874 276.6 5e-74 NP_001127904 (OMIM: 609916) 5-azacytidine-induced ( 243) 1381 207.0 4e-53 XP_011532312 (OMIM: 609916) PREDICTED: 5-azacytidi ( 246) 1381 207.0 4e-53 NP_001127905 (OMIM: 609916) 5-azacytidine-induced ( 232) 1370 205.4 1.1e-52 XP_011532313 (OMIM: 609916) PREDICTED: 5-azacytidi ( 235) 1370 205.4 1.1e-52 XP_016880921 (OMIM: 608476) PREDICTED: TANK-bindin ( 613) 208 41.8 0.0054 XP_016880920 (OMIM: 608476) PREDICTED: TANK-bindin ( 614) 205 41.4 0.0073 XP_005257916 (OMIM: 608476) PREDICTED: TANK-bindin ( 615) 205 41.4 0.0073 XP_005257917 (OMIM: 608476) PREDICTED: TANK-bindin ( 615) 205 41.4 0.0073 XP_005257919 (OMIM: 608476) PREDICTED: TANK-bindin ( 615) 205 41.4 0.0073 XP_005257918 (OMIM: 608476) PREDICTED: TANK-bindin ( 615) 205 41.4 0.0073 NP_055541 (OMIM: 608476) TANK-binding kinase 1-bin ( 615) 205 41.4 0.0073 >>NP_071906 (OMIM: 609916) 5-azacytidine-induced protein (392 aa) initn: 2586 init1: 2586 opt: 2586 Z-score: 1991.0 bits: 377.2 E(85289): 3.7e-104 Smith-Waterman score: 2586; 100.0% identity (100.0% similar) in 392 aa overlap (1-392:1-392) 10 20 30 40 50 60 pF1KB6 MDALVEDDICILNHEKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEKENS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 MDALVEDDICILNHEKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEKENS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 LLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKDNSES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 LLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKDNSES 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 LKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKIHGLEQELELMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 LKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKIHGLEQELELMR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 KECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSISSDNMQHAYWELKREMSNLHLVTQVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 KECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSISSDNMQHAYWELKREMSNLHLVTQVQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 AELLRKLKTSTAIKKACAPVGCSEDLGRDSTKLHLMNFTATYTRHPPLLPNGKALCHTTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 AELLRKLKTSTAIKKACAPVGCSEDLGRDSTKLHLMNFTATYTRHPPLLPNGKALCHTTS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 SPLPGDVKVLSEKAILQSWTDNERSIPNDGTCFQEHSSYGRNSLEDNSWVFPSPPKSSET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_071 SPLPGDVKVLSEKAILQSWTDNERSIPNDGTCFQEHSSYGRNSLEDNSWVFPSPPKSSET 310 320 330 340 350 360 370 380 390 pF1KB6 AFGETKTKTLPLPNLPPLHYLDQHNQNCLYKN :::::::::::::::::::::::::::::::: NP_071 AFGETKTKTLPLPNLPPLHYLDQHNQNCLYKN 370 380 390 >>XP_005265449 (OMIM: 609916) PREDICTED: 5-azacytidine-i (392 aa) initn: 2586 init1: 2586 opt: 2586 Z-score: 1991.0 bits: 377.2 E(85289): 3.7e-104 Smith-Waterman score: 2586; 100.0% identity (100.0% similar) in 392 aa overlap (1-392:1-392) 10 20 30 40 50 60 pF1KB6 MDALVEDDICILNHEKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEKENS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MDALVEDDICILNHEKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEKENS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 LLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKDNSES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKDNSES 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 LKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKIHGLEQELELMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 LKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKIHGLEQELELMR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 KECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSISSDNMQHAYWELKREMSNLHLVTQVQ :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 KECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSISSDNMQHAYWELKREMSNLHLVTQVQ 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 AELLRKLKTSTAIKKACAPVGCSEDLGRDSTKLHLMNFTATYTRHPPLLPNGKALCHTTS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 AELLRKLKTSTAIKKACAPVGCSEDLGRDSTKLHLMNFTATYTRHPPLLPNGKALCHTTS 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 SPLPGDVKVLSEKAILQSWTDNERSIPNDGTCFQEHSSYGRNSLEDNSWVFPSPPKSSET :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SPLPGDVKVLSEKAILQSWTDNERSIPNDGTCFQEHSSYGRNSLEDNSWVFPSPPKSSET 310 320 330 340 350 360 370 380 390 pF1KB6 AFGETKTKTLPLPNLPPLHYLDQHNQNCLYKN :::::::::::::::::::::::::::::::: XP_005 AFGETKTKTLPLPNLPPLHYLDQHNQNCLYKN 370 380 390 >>XP_011532311 (OMIM: 609916) PREDICTED: 5-azacytidine-i (395 aa) initn: 2586 init1: 2586 opt: 2586 Z-score: 1991.0 bits: 377.2 E(85289): 3.7e-104 Smith-Waterman score: 2586; 100.0% identity (100.0% similar) in 392 aa overlap (1-392:4-395) 10 20 30 40 50 pF1KB6 MDALVEDDICILNHEKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEK ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MVVMDALVEDDICILNHEKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEK 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 ENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKDN 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 SESLKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKIHGLEQELE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SESLKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKIHGLEQELE 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB6 LMRKECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSISSDNMQHAYWELKREMSNLHLVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 LMRKECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSISSDNMQHAYWELKREMSNLHLVT 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB6 QVQAELLRKLKTSTAIKKACAPVGCSEDLGRDSTKLHLMNFTATYTRHPPLLPNGKALCH :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 QVQAELLRKLKTSTAIKKACAPVGCSEDLGRDSTKLHLMNFTATYTRHPPLLPNGKALCH 250 260 270 280 290 300 300 310 320 330 340 350 pF1KB6 TTSSPLPGDVKVLSEKAILQSWTDNERSIPNDGTCFQEHSSYGRNSLEDNSWVFPSPPKS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 TTSSPLPGDVKVLSEKAILQSWTDNERSIPNDGTCFQEHSSYGRNSLEDNSWVFPSPPKS 310 320 330 340 350 360 360 370 380 390 pF1KB6 SETAFGETKTKTLPLPNLPPLHYLDQHNQNCLYKN ::::::::::::::::::::::::::::::::::: XP_011 SETAFGETKTKTLPLPNLPPLHYLDQHNQNCLYKN 370 380 390 >>NP_001258579 (OMIM: 609916) 5-azacytidine-induced prot (280 aa) initn: 1874 init1: 1874 opt: 1874 Z-score: 1450.0 bits: 276.6 E(85289): 5e-74 Smith-Waterman score: 1874; 100.0% identity (100.0% similar) in 280 aa overlap (113-392:1-280) 90 100 110 120 130 140 pF1KB6 SVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKDNSESLKVLNEQLQSKEVELLQLRTEV :::::::::::::::::::::::::::::: NP_001 MNKDNSESLKVLNEQLQSKEVELLQLRTEV 10 20 30 150 160 170 180 190 200 pF1KB6 ETQQVMRNLNPPSSNWEVEKLSCDLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQED :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ETQQVMRNLNPPSSNWEVEKLSCDLKIHGLEQELELMRKECSDLKIELQKAKQTDPYQED 40 50 60 70 80 90 210 220 230 240 250 260 pF1KB6 NLKSRDLQKLSISSDNMQHAYWELKREMSNLHLVTQVQAELLRKLKTSTAIKKACAPVGC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NLKSRDLQKLSISSDNMQHAYWELKREMSNLHLVTQVQAELLRKLKTSTAIKKACAPVGC 100 110 120 130 140 150 270 280 290 300 310 320 pF1KB6 SEDLGRDSTKLHLMNFTATYTRHPPLLPNGKALCHTTSSPLPGDVKVLSEKAILQSWTDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 SEDLGRDSTKLHLMNFTATYTRHPPLLPNGKALCHTTSSPLPGDVKVLSEKAILQSWTDN 160 170 180 190 200 210 330 340 350 360 370 380 pF1KB6 ERSIPNDGTCFQEHSSYGRNSLEDNSWVFPSPPKSSETAFGETKTKTLPLPNLPPLHYLD :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 ERSIPNDGTCFQEHSSYGRNSLEDNSWVFPSPPKSSETAFGETKTKTLPLPNLPPLHYLD 220 230 240 250 260 270 390 pF1KB6 QHNQNCLYKN :::::::::: NP_001 QHNQNCLYKN 280 >>NP_001127904 (OMIM: 609916) 5-azacytidine-induced prot (243 aa) initn: 1412 init1: 1372 opt: 1381 Z-score: 1074.8 bits: 207.0 E(85289): 4e-53 Smith-Waterman score: 1381; 96.4% identity (98.2% similar) in 224 aa overlap (1-224:1-224) 10 20 30 40 50 60 pF1KB6 MDALVEDDICILNHEKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEKENS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDALVEDDICILNHEKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEKENS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 LLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKDNSES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKDNSES 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 LKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKIHGLEQELELMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKIHGLEQELELMR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 KECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSISSDNMQHAYWELKREMSNLHLVTQVQ ::::::::::::::::::::::::::::::::::: ... . : NP_001 KECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSISRQSICSTAWSAVAQSWDSMNFEDCS 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 AELLRKLKTSTAIKKACAPVGCSEDLGRDSTKLHLMNFTATYTRHPPLLPNGKALCHTTS NP_001 LFA >>XP_011532312 (OMIM: 609916) PREDICTED: 5-azacytidine-i (246 aa) initn: 1412 init1: 1372 opt: 1381 Z-score: 1074.7 bits: 207.0 E(85289): 4e-53 Smith-Waterman score: 1381; 96.4% identity (98.2% similar) in 224 aa overlap (1-224:4-227) 10 20 30 40 50 pF1KB6 MDALVEDDICILNHEKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEK ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MVVMDALVEDDICILNHEKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEK 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 ENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKDN 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 SESLKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKIHGLEQELE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SESLKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKIHGLEQELE 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB6 LMRKECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSISSDNMQHAYWELKREMSNLHLVT :::::::::::::::::::::::::::::::::::::: ... . : XP_011 LMRKECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSISRQSICSTAWSAVAQSWDSMNFE 190 200 210 220 230 240 240 250 260 270 280 290 pF1KB6 QVQAELLRKLKTSTAIKKACAPVGCSEDLGRDSTKLHLMNFTATYTRHPPLLPNGKALCH XP_011 DCSLFA >>NP_001127905 (OMIM: 609916) 5-azacytidine-induced prot (232 aa) initn: 1370 init1: 1370 opt: 1370 Z-score: 1066.7 bits: 205.4 E(85289): 1.1e-52 Smith-Waterman score: 1370; 100.0% identity (100.0% similar) in 215 aa overlap (1-215:1-215) 10 20 30 40 50 60 pF1KB6 MDALVEDDICILNHEKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEKENS :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MDALVEDDICILNHEKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEKENS 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 LLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKDNSES :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKDNSES 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 LKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKIHGLEQELELMR :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 LKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKIHGLEQELELMR 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 KECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSISSDNMQHAYWELKREMSNLHLVTQVQ ::::::::::::::::::::::::::::::::::: NP_001 KECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSISRVSVAQPGVQWRNHGIA 190 200 210 220 230 250 260 270 280 290 300 pF1KB6 AELLRKLKTSTAIKKACAPVGCSEDLGRDSTKLHLMNFTATYTRHPPLLPNGKALCHTTS >>XP_011532313 (OMIM: 609916) PREDICTED: 5-azacytidine-i (235 aa) initn: 1370 init1: 1370 opt: 1370 Z-score: 1066.6 bits: 205.4 E(85289): 1.1e-52 Smith-Waterman score: 1370; 100.0% identity (100.0% similar) in 215 aa overlap (1-215:4-218) 10 20 30 40 50 pF1KB6 MDALVEDDICILNHEKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEK ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MVVMDALVEDDICILNHEKAHKRDTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSEK 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 ENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKDN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ENSLLKKRIRFLEEKLIARFEEETSSVGREQVNKAYHAYREVCIDRDNLKSKLDKMNKDN 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 SESLKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKIHGLEQELE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SESLKVLNEQLQSKEVELLQLRTEVETQQVMRNLNPPSSNWEVEKLSCDLKIHGLEQELE 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB6 LMRKECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSISSDNMQHAYWELKREMSNLHLVT :::::::::::::::::::::::::::::::::::::: XP_011 LMRKECSDLKIELQKAKQTDPYQEDNLKSRDLQKLSISRVSVAQPGVQWRNHGIA 190 200 210 220 230 240 250 260 270 280 290 pF1KB6 QVQAELLRKLKTSTAIKKACAPVGCSEDLGRDSTKLHLMNFTATYTRHPPLLPNGKALCH >>XP_016880921 (OMIM: 608476) PREDICTED: TANK-binding ki (613 aa) initn: 207 init1: 145 opt: 208 Z-score: 174.7 bits: 41.8 E(85289): 0.0054 Smith-Waterman score: 221; 24.9% identity (51.7% similar) in 321 aa overlap (1-247:1-320) 10 20 30 40 50 pF1KB6 MDALVEDDICILNHEKAHKR----DTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSE :... :::: ::..: :. :. .:: ::::::.::: :::.:: : XP_016 MESMFEDDISILTQEALGPSEVWLDSPGDPSL-GGDMCSASHFALITAYGDIKERLGGLE 10 20 30 40 50 60 70 80 pF1KB6 KENSLLKKRIRFLE----------------------------EKL-----IARFEEETSS .::. :..:.. : ::. . .:..: .. XP_016 RENATLRRRLKVYEIKYPLISDFGEEHGFSLYEIKDGSLLEVEKVSLQQRLNQFQHEKNK 60 70 80 90 100 110 90 100 110 120 130 pF1KB6 VGREQVNKAYHAYREVCIDRDNLKSKLDKMNKDNSESLKV---LNEQLQSKE-------- .::... .::...:.....:...: .: :. :..::.... XP_016 EQEEQLGEMIQAYEKLCVEKSDLETELREMRALVETHLRQICGLEQQLRQQQGLQDAAFS 120 130 140 150 160 170 140 150 160 170 pF1KB6 ----------------VELLQLRTEVETQQVMRNLNPPS-SNWEVEKLSCDLKI-----H .. : :: ... . :: :. : ..: :. . XP_016 NLSPPPAPAPPCTDLDLHYLALRGGSGLSHAGWPGSTPSVSDLERRRLEEALEAAQGEAR 180 190 200 210 220 230 180 190 200 210 220 pF1KB6 GLEQELELMRKECSDLKIELQKAKQTDPYQ-EDNLKSRDLQKLSISSD---NMQHAYWEL : . . : .. :: :. ::.. ..: . .: . ::. .. .: :. :: :: XP_016 GAQLREEQLQAECERLQGELKQLQETRAQDLASNQSERDMAWVKRVGDDQVNLALAYTEL 240 250 260 270 280 290 230 240 250 260 270 280 pF1KB6 KREMSNLHLVTQVQAELLRKLKTSTAIKKACAPVGCSEDLGRDSTKLHLMNFTATYTRHP .:.. :. ....:...:: : XP_016 TEELGRLRELSSLQGRILRTLLQEQARSGGQRHSPLSQRHSPAPQCPSPSPPARAAPPCP 300 310 320 330 340 350 >>XP_016880920 (OMIM: 608476) PREDICTED: TANK-binding ki (614 aa) initn: 207 init1: 145 opt: 205 Z-score: 172.4 bits: 41.4 E(85289): 0.0073 Smith-Waterman score: 222; 28.2% identity (51.4% similar) in 323 aa overlap (1-247:1-321) 10 20 30 40 50 pF1KB6 MDALVEDDICILNHEKAHKR----DTVTPVSIYSGDESVASHFALVTAYEDIKKRLKDSE :... :::: ::..: :. :. .:: ::::::.::: :::.:: : XP_016 MESMFEDDISILTQEALGPSEVWLDSPGDPSL-GGDMCSASHFALITAYGDIKERLGGLE 10 20 30 40 50 60 70 80 90 100 110 pF1KB6 KENSLLKKRIRFLEEK--LIARFEEETSSVGREQVNKAYHAYREVCIDR--DNLKSKLDK .::. :..:.. : : ::. : :: . : . . ..: ... .... .:.: XP_016 RENATLRRRLKVYEIKYPLISDFGEEHGFSLYEIKDGSLLEVEKVSLQQRLNQFQHELQK 60 70 80 90 100 110 120 130 140 pF1KB6 MNKDNSESLKVL---NEQL----QSKEVELLQLRTEVET--------QQVMR-------- ::.. :.: . :.: .. :.:: ..:. ::: .: .: XP_016 -NKEQEEQLGEMIQAYEKLCVEKSDLETELREMRALVETHLRQICGLEQQLRQQQGLQDA 120 130 140 150 160 170 150 160 170 pF1KB6 ---NLNPP-----------------------SSNWEVEKLSC-DLKIHGLEQELEL---- ::.:: : .: : ::. . ::. :: XP_016 AFSNLSPPPAPAPPCTDLDLHYLALRGGSGLSHGWPGSTPSVSDLERRRLEEALEAAQGE 180 190 200 210 220 230 180 190 200 210 220 pF1KB6 ----------MRKECSDLKIELQKAKQTDPYQ-EDNLKSRDLQKLSISSD---NMQHAYW .. :: :. ::.. ..: . .: . ::. .. .: :. :: XP_016 ARGAQLREEQLQAECERLQGELKQLQETRAQDLASNQSERDMAWVKRVGDDQVNLALAYT 240 250 260 270 280 290 230 240 250 260 270 280 pF1KB6 ELKREMSNLHLVTQVQAELLRKLKTSTAIKKACAPVGCSEDLGRDSTKLHLMNFTATYTR :: .:.. :. ....:...:: : XP_016 ELTEELGRLRELSSLQGRILRTLLQEQARSGGQRHSPLSQRHSPAPQCPSPSPPARAAPP 300 310 320 330 340 350 392 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 20:26:20 2016 done: Sat Nov 5 20:26:21 2016 Total Scan time: 8.530 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]