Result of FASTA (omim) for pF1KB6552
FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011
Please cite:
W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448

Query: pF1KB6552, 394 aa
  1>>>pF1KB6552 394 - 394 aa - 394 aa
Library: /omim/omim.rfq.tfa
  60827320 residues in 85289 sequences

Statistics:  Expectation_n fit: rho(ln(x))= 6.2945+/-0.000275; mu= 13.3943+/- 0.018
 mean_var=97.0816+/-19.611, 0's: 0 Z-trim(120.7): 139  B-trim: 1992 in 1/56
 Lambda= 0.130168
 statistics sampled from 36154 (36309) to 36154 sequences
Algorithm: FASTA (3.7 Nov 2010) [optimized]
Parameters: BL50 matrix (15:-5), open/ext: -10/-2
 ktup: 2, E-join: 1 (0.757), E-opt: 0.2 (0.426), width:  16
 Scan time:  9.210

The best scores are:                                      opt bits E(85289)
NP_001385 (OMIM: 602747) dual specificity protein  ( 394) 2644 506.3 5.3e-143
NP_476499 (OMIM: 602747) dual specificity protein  ( 303) 1717 332.1 1.1e-90
XP_011542730 (OMIM: 602747) PREDICTED: dual specif ( 303) 1717 332.1 1.1e-90
NP_004408 (OMIM: 600714) dual specificity protein  ( 367) 1521 295.3 1.5e-79
NP_004410 (OMIM: 603069) dual specificity protein  ( 384)  963 190.6 5.5e-48
NP_004409 (OMIM: 603068) dual specificity protein  ( 314)  947 187.5 3.8e-47
XP_016859035 (OMIM: 603068) PREDICTED: dual specif ( 342)  786 157.3 5.1e-38
NP_009138 (OMIM: 608867) dual specificity protein  ( 482)  582 119.1 2.3e-26
NP_001938 (OMIM: 602749) dual specificity protein  ( 419)  477 99.3 1.8e-20
NP_001937 (OMIM: 602748,615269) dual specificity p ( 381)  472 98.4 3.2e-20
XP_011529426 (OMIM: 300134) PREDICTED: dual specif ( 384)  454 95.0 3.3e-19
NP_001305432 (OMIM: 300134) dual specificity prote ( 384)  454 95.0 3.3e-19
NP_001386 (OMIM: 300134) dual specificity protein  ( 384)  454 95.0 3.3e-19
XP_011529425 (OMIM: 300134) PREDICTED: dual specif ( 415)  454 95.0 3.5e-19
NP_004411 (OMIM: 602038) dual specificity protein  ( 625)  415 87.8 7.9e-17
XP_011518235 (OMIM: 602038) PREDICTED: dual specif ( 625)  415 87.8 7.9e-17
XP_011518234 (OMIM: 602038) PREDICTED: dual specif ( 625)  415 87.8 7.9e-17
NP_085143 (OMIM: 607175) dual specificity protein  ( 665)  402 85.4 4.5e-16
XP_006719218 (OMIM: 607175) PREDICTED: dual specif ( 665)  402 85.4 4.5e-16
XP_011519159 (OMIM: 607175) PREDICTED: dual specif ( 665)  402 85.4 4.5e-16
XP_011519158 (OMIM: 607175) PREDICTED: dual specif ( 665)  402 85.4 4.5e-16
XP_011522536 (OMIM: 606618) PREDICTED: dual specif ( 198)  367 78.5 1.6e-14
XP_005257034 (OMIM: 606618) PREDICTED: dual specif ( 198)  367 78.5 1.6e-14
NP_008957 (OMIM: 606618) dual specificity protein  ( 198)  367 78.5 1.6e-14
XP_016875477 (OMIM: 607175) PREDICTED: dual specif ( 517)  347 75.0 4.7e-13
XP_005253545 (OMIM: 607175) PREDICTED: dual specif ( 517)  347 75.0 4.7e-13
NP_001154802 (OMIM: 606778) protein phosphatase Sl ( 692)  326 71.1 9.2e-12
NP_001154803 (OMIM: 606778) protein phosphatase Sl ( 703)  326 71.1 9.3e-12
XP_016880742 (OMIM: 606779) PREDICTED: protein pho ( 529)  324 70.7 9.6e-12
XP_016874981 (OMIM: 606778) PREDICTED: protein pho ( 923)  326 71.2 1.2e-11
XP_011536803 (OMIM: 606778) PREDICTED: protein pho ( 969)  326 71.2 1.2e-11
XP_005269042 (OMIM: 606778) PREDICTED: protein pho ( 969)  326 71.2 1.2e-11
XP_011536802 (OMIM: 606778) PREDICTED: protein pho ( 969)  326 71.2 1.2e-11
XP_016874980 (OMIM: 606778) PREDICTED: protein pho (1033)  326 71.2 1.3e-11
NP_061857 (OMIM: 606778) protein phosphatase Sling (1049)  326 71.2 1.3e-11
XP_005269041 (OMIM: 606778) PREDICTED: protein pho (1049)  326 71.2 1.3e-11
XP_011536799 (OMIM: 606778) PREDICTED: protein pho (1060)  326 71.2 1.3e-11
XP_011528222 (OMIM: 611446) PREDICTED: dual specif ( 188)  315 68.7 1.3e-11
XP_005261425 (OMIM: 611446) PREDICTED: dual specif ( 188)  315 68.7 1.3e-11
NP_689724 (OMIM: 611446) dual specificity protein  ( 188)  315 68.7 1.3e-11
XP_006724211 (OMIM: 611446) PREDICTED: dual specif ( 188)  315 68.7 1.3e-11
XP_016884117 (OMIM: 611446) PREDICTED: dual specif ( 188)  315 68.7 1.3e-11
NP_001291724 (OMIM: 611446) dual specificity prote ( 188)  315 68.7 1.3e-11
XP_016884116 (OMIM: 611446) PREDICTED: dual specif ( 188)  315 68.7 1.3e-11
NP_001291723 (OMIM: 611446) dual specificity prote ( 188)  315 68.7 1.3e-11
XP_011528223 (OMIM: 611446) PREDICTED: dual specif ( 188)  315 68.7 1.3e-11
XP_016880743 (OMIM: 606779) PREDICTED: protein pho ( 480)  320 69.9 1.5e-11
XP_016880741 (OMIM: 606779) PREDICTED: protein pho (1328)  322 70.5 2.6e-11
XP_011523708 (OMIM: 606779) PREDICTED: protein pho (1347)  322 70.5 2.7e-11
XP_011523709 (OMIM: 606779) PREDICTED: protein pho (1347)  322 70.5 2.7e-11


>>NP_001385 (OMIM: 602747) dual specificity protein phos  (394 aa)
 initn: 2644 init1: 2644 opt: 2644  Z-score: 2688.3  bits: 506.3 E(85289): 5.3e-143
Smith-Waterman score: 2644; 100.0% identity (100.0% similar) in 394 aa overlap (1-394:1-394)

               10        20        30        40        50        60
pF1KB6 MVTMEELREMDCSVLKRLMNRDENGGGAGGSGSHGTLGLPSGGKCLLLDCRPFLAHSAGY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 MVTMEELREMDCSVLKRLMNRDENGGGAGGSGSHGTLGLPSGGKCLLLDCRPFLAHSAGY
               10        20        30        40        50        60

               70        80        90       100       110       120
pF1KB6 ILGSVNVRCNTIVRRRAKGSVSLEQILPAEEEVRARLRSGLYSAVIVYDERSPRAESLRE
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 ILGSVNVRCNTIVRRRAKGSVSLEQILPAEEEVRARLRSGLYSAVIVYDERSPRAESLRE
               70        80        90       100       110       120

              130       140       150       160       170       180
pF1KB6 DSTVSLVVQALRRNAERTDICLLKGGYERFSSEYPEFCSKTKALAAIPPPVPPSATEPLD
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 DSTVSLVVQALRRNAERTDICLLKGGYERFSSEYPEFCSKTKALAAIPPPVPPSATEPLD
              130       140       150       160       170       180

              190       200       210       220       230       240
pF1KB6 LGCSSCGTPLHDQGGPVEILPFLYLGSAYHAARRDMLDALGITALLNVSSDCPNHFEGHY
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 LGCSSCGTPLHDQGGPVEILPFLYLGSAYHAARRDMLDALGITALLNVSSDCPNHFEGHY
              190       200       210       220       230       240

              250       260       270       280       290       300
pF1KB6 QYKCIPVEDNHKADISSWFMEAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKR
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 QYKCIPVEDNHKADISSWFMEAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKR
              250       260       270       280       290       300

              310       320       330       340       350       360
pF1KB6 VRLEEAFEFVKQRRSIISPNFSFMGQLLQFESQVLATSCAAEAASPSGPLRERGKTPATP
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_001 VRLEEAFEFVKQRRSIISPNFSFMGQLLQFESQVLATSCAAEAASPSGPLRERGKTPATP
              310       320       330       340       350       360

              370       380       390    
pF1KB6 TSQFVFSFPVSVGVHSAPSSLPYLHSPITTSPSC
       ::::::::::::::::::::::::::::::::::
NP_001 TSQFVFSFPVSVGVHSAPSSLPYLHSPITTSPSC
              370       380       390    

>>NP_476499 (OMIM: 602747) dual specificity protein phos  (303 aa)
 initn: 1712 init1: 1712 opt: 1717  Z-score: 1749.2  bits: 332.1 E(85289): 1.1e-90
Smith-Waterman score: 1717; 90.7% identity (93.4% similar) in 289 aa overlap (111-394:17-303)

               90       100       110       120       130          
pF1KB6 VSLEQILPAEEEVRARLRSGLYSAVIVYDERSPRAESLREDSTVSLVVQAL--RRNAERT
                                     :::: .. :. . :    .::   . : :.
NP_476               MGRKVHSNGSQFAEHSRSPR-RTGRDCKPVRAPSMALGVSQLAGRS
                             10        20         30        40     

      140          150       160       170       180       190     
pF1KB6 DICLL---KGGYERFSSEYPEFCSKTKALAAIPPPVPPSATEPLDLGCSSCGTPLHDQGG
         ::    .:::::::::::::::::::::::::::::::::::::::::::::::::::
NP_476 R-CLCSESQGGYERFSSEYPEFCSKTKALAAIPPPVPPSATEPLDLGCSSCGTPLHDQGG
           50        60        70        80        90       100    

         200       210       220       230       240       250     
pF1KB6 PVEILPFLYLGSAYHAARRDMLDALGITALLNVSSDCPNHFEGHYQYKCIPVEDNHKADI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_476 PVEILPFLYLGSAYHAARRDMLDALGITALLNVSSDCPNHFEGHYQYKCIPVEDNHKADI
          110       120       130       140       150       160    

         260       270       280       290       300       310     
pF1KB6 SSWFMEAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEFVKQRRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_476 SSWFMEAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEFVKQRRS
          170       180       190       200       210       220    

         320       330       340       350       360       370     
pF1KB6 IISPNFSFMGQLLQFESQVLATSCAAEAASPSGPLRERGKTPATPTSQFVFSFPVSVGVH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
NP_476 IISPNFSFMGQLLQFESQVLATSCAAEAASPSGPLRERGKTPATPTSQFVFSFPVSVGVH
          230       240       250       260       270       280    

         380       390    
pF1KB6 SAPSSLPYLHSPITTSPSC
       :::::::::::::::::::
NP_476 SAPSSLPYLHSPITTSPSC
          290       300   

>>XP_011542730 (OMIM: 602747) PREDICTED: dual specificit  (303 aa)
 initn: 1712 init1: 1712 opt: 1717  Z-score: 1749.2  bits: 332.1 E(85289): 1.1e-90
Smith-Waterman score: 1717; 90.7% identity (93.4% similar) in 289 aa overlap (111-394:17-303)

               90       100       110       120       130          
pF1KB6 VSLEQILPAEEEVRARLRSGLYSAVIVYDERSPRAESLREDSTVSLVVQAL--RRNAERT
                                     :::: .. :. . :    .::   . : :.
XP_011               MGRKVHSNGSQFAEHSRSPR-RTGRDCKPVRAPSMALGVSQLAGRS
                             10        20         30        40     

      140          150       160       170       180       190     
pF1KB6 DICLL---KGGYERFSSEYPEFCSKTKALAAIPPPVPPSATEPLDLGCSSCGTPLHDQGG
         ::    .:::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 R-CLCSESQGGYERFSSEYPEFCSKTKALAAIPPPVPPSATEPLDLGCSSCGTPLHDQGG
           50        60        70        80        90       100    

         200       210       220       230       240       250     
pF1KB6 PVEILPFLYLGSAYHAARRDMLDALGITALLNVSSDCPNHFEGHYQYKCIPVEDNHKADI
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 PVEILPFLYLGSAYHAARRDMLDALGITALLNVSSDCPNHFEGHYQYKCIPVEDNHKADI
          110       120       130       140       150       160    

         260       270       280       290       300       310     
pF1KB6 SSWFMEAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEFVKQRRS
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 SSWFMEAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEFVKQRRS
          170       180       190       200       210       220    

         320       330       340       350       360       370     
pF1KB6 IISPNFSFMGQLLQFESQVLATSCAAEAASPSGPLRERGKTPATPTSQFVFSFPVSVGVH
       ::::::::::::::::::::::::::::::::::::::::::::::::::::::::::::
XP_011 IISPNFSFMGQLLQFESQVLATSCAAEAASPSGPLRERGKTPATPTSQFVFSFPVSVGVH
          230       240       250       260       270       280    

         380       390    
pF1KB6 SAPSSLPYLHSPITTSPSC
       :::::::::::::::::::
XP_011 SAPSSLPYLHSPITTSPSC
          290       300   

>>NP_004408 (OMIM: 600714) dual specificity protein phos  (367 aa)
 initn: 1387 init1: 1189 opt: 1521  Z-score: 1549.0  bits: 295.3 E(85289): 1.5e-79
Smith-Waterman score: 1521; 63.1% identity (83.5% similar) in 369 aa overlap (26-394:6-367)

               10        20        30        40        50        60
pF1KB6 MVTMEELREMDCSVLKRLMNRDENGGGAGGSGSHGTLGLPSGGKCLLLDCRPFLAHSAGY
                                :   ..: .. ::   ...::::::: :.: .::.
NP_004                     MVMEVGTLDAGGLRALLG-ERAAQCLLLDCRSFFAFNAGH
                                   10         20        30         

               70        80        90       100       110       120
pF1KB6 ILGSVNVRCNTIVRRRAKGSVSLEQILPAEEEVRARLRSGLYSAVIVYDERSPRAESLRE
       : :::::: .:::::::::...::.:.: . :.:.:: .: : ::.. ::::   .. ..
NP_004 IAGSVNVRFSTIVRRRAKGAMGLEHIVP-NAELRGRLLAGAYHAVVLLDERSAALDGAKR
      40        50        60         70        80        90        

              130       140       150       160       170       180
pF1KB6 DSTVSLVVQALRRNAERTDICLLKGGYERFSSEYPEFCSKTKALAAIPPPVPPSATEPLD
       :.:..:.. :: :.:. ... .:::::: ::.  ::.::: ..  ..  :.  :. .  .
NP_004 DGTLALAAGALCREARAAQVFFLKGGYEAFSASCPELCSKQSTPMGLSLPLSTSVPDSAE
      100       110       120       130       140       150        

              190       200       210       220       230       240
pF1KB6 LGCSSCGTPLHDQGGPVEILPFLYLGSAYHAARRDMLDALGITALLNVSSDCPNHFEGHY
        :::::.:::.::::::::::::::::::::.:.:::::::::::.:::..:::::::::
NP_004 SGCSSCSTPLYDQGGPVEILPFLYLGSAYHASRKDMLDALGITALINVSANCPNHFEGHY
      160       170       180       190       200       210        

              250       260       270       280       290       300
pF1KB6 QYKCIPVEDNHKADISSWFMEAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKR
       ::: ::::::::::::::: :::..::..:.  :::.:::::::::::::::::::  .:
NP_004 QYKSIPVEDNHKADISSWFNEAIDFIDSIKNAGGRVFVHCQAGISRSATICLAYLMRTNR
      220       230       240       250       260       270        

              310       320       330       340       350       360
pF1KB6 VRLEEAFEFVKQRRSIISPNFSFMGQLLQFESQVLATSCAAEAASPSGPLRERGKTPATP
       :.:.::::::::::::::::::::::::::::::::  :.:::.::.  . .:: . .: 
NP_004 VKLDEAFEFVKQRRSIISPNFSFMGQLLQFESQVLAPHCSAEAGSPAMAVLDRGTSTTT-
      280       290       300       310       320       330        

              370       380       390    
pF1KB6 TSQFVFSFPVSVGVHSAPSSLPYLHSPITTSPSC
           ::.::::. :::. :.: ::.:::::::::
NP_004 ----VFNFPVSIPVHSTNSALSYLQSPITTSPSC
           340       350       360       

>>NP_004410 (OMIM: 603069) dual specificity protein phos  (384 aa)
 initn: 952 init1: 635 opt: 963  Z-score: 982.4  bits: 190.6 E(85289): 5.5e-48
Smith-Waterman score: 971; 46.7% identity (67.7% similar) in 381 aa overlap (41-394:19-384)

               20        30        40        50        60        70
pF1KB6 DCSVLKRLMNRDENGGGAGGSGSHGTLGLPSGGKCLLLDCRPFLAHSAGYILGSVNVRCN
                                     ....:..:::::.:: .:. . ::.::  :
NP_004             MKVTSLDGRQLRKMLRKEAAARCVVLDCRPYLAFAASNVRGSLNVNLN
                           10        20        30        40        

                80        90          100       110       120      
pF1KB6 TIVRRRAKG-SVSLEQILPAEEEVRARLRS---GLYSAVIVYDERSPRAESLREDSTVSL
       ..: :::.: .:: . .:: .: .:::: .   :  .::.: :. : . ..:::.:.. .
NP_004 SVVLRRARGGAVSARYVLP-DEAARARLLQEGGGGVAAVVVLDQGSRHWQKLREESAARV
       50        60         70        80        90       100       

        130        140       150       160       170       180     
pF1KB6 VVQALRRNAERTD-ICLLKGGYERFSSEYPEFCSKTKALAAIPPPVPPSATEPLDLGCSS
       :. .:         . .:::::: : ::::: :  .:       :.     :      :.
NP_004 VLTSLLACLPAGPRVYFLKGGYETFYSEYPECCVDVK-------PISQEKIESERALISQ
       110       120       130       140              150       160

         190               200       210       220       230       
pF1KB6 CGTPL--------HDQGGPVEILPFLYLGSAYHAARRDMLDALGITALLNVSSDCPNHFE
       :: :.        .::::::::::::::::::::.. ..:  : ::::::::    .   
NP_004 CGKPVVNVSYRPAYDQGGPVEILPFLYLGSAYHASKCEFLANLHITALLNVSRRTSEACA
              170       180       190       200       210       220

       240       250       260       270       280       290       
pF1KB6 GHYQYKCIPVEDNHKADISSWFMEAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMM
        : .:: :::::.: ::::: :.:::..:: :..  :.:::::.:::::: :::.:::: 
NP_004 THLHYKWIPVEDSHTADISSHFQEAIDFIDCVREKGGKVLVHCEAGISRSPTICMAYLMK
              230       240       250       260       270       280

       300       310       320       330              340          
pF1KB6 KKRVRLEEAFEFVKQRRSIISPNFSFMGQLLQFESQVLAT-------SCAAEAASPS--G
        :. ::.:::...:::::..::::.:::::::.::..: .       :: .:::. :  :
NP_004 TKQFRLKEAFDYIKQRRSMVSPNFGFMGQLLQYESEILPSTPNPQPPSCQGEAAGSSLIG
              290       300       310       320       330       340

      350       360        370           380       390    
pF1KB6 PLRERGKTPATPTSQFVF-SFPVSV----GVHSAPSSLPYLHSPITTSPSC
        :.       .:  : .. .::.::     .::. : :   .::..:. ::
NP_004 HLQT-----LSPDMQGAYCTFPASVLAPVPTHSTVSELS--RSPVATATSC
                   350       360       370         380    

>>NP_004409 (OMIM: 603068) dual specificity protein phos  (314 aa)
 initn: 866 init1: 729 opt: 947  Z-score: 967.5  bits: 187.5 E(85289): 3.8e-47
Smith-Waterman score: 950; 48.2% identity (71.4% similar) in 336 aa overlap (4-335:3-312)

               10        20        30        40        50        60
pF1KB6 MVTMEELREMDCSVLKRLMNRDENGGGAGGSGSHGTLGLPSGGKCLLLDCRPFLAHSAGY
          .:  ::..:..:  :. ::                   . . ::::::::::    .
NP_004  MGLEAARELECAALGTLL-RDPR----------------EAERTLLLDCRPFLAFCRRH
                10         20                        30        40  

               70          80        90       100       110        
pF1KB6 ILGSVNVRCNTIVRRRAKG--SVSLEQILPAEEEVRARLRSGLYSAVIVYDERSPRAESL
       . ..  :  :...::::.:  .. :  .:: .. .:.::  :  . ..: :: :  .  :
NP_004 VRAARPVPWNALLRRRARGPPAAVLACLLP-DRALRTRLVRGELARAVVLDEGSASVAEL
             50        60        70         80        90       100 

      120       130         140       150       160       170      
pF1KB6 REDSTVSLVVQAL--RRNAERTDICLLKGGYERFSSEYPEFCSKTKALAAIPPPVPPSAT
       : :: . ... ::  .  :  : . .:.::.. :..  :..::.. :     : .::.. 
NP_004 RPDSPAHVLLAALLHETRAGPTAVYFLRGGFDGFQGCCPDLCSEAPA-----PALPPTGD
             110       120       130       140            150      

        180       190       200       210       220       230      
pF1KB6 EPLDLGCSSCGTPLHDQGGPVEILPFLYLGSAYHAARRDMLDALGITALLNVSSDCPNHF
       .    . :.  .:..::::::::::.:.:::  :..  . :.: ::::.::::..:::::
NP_004 KT---SRSDSRAPVYDQGGPVEILPYLFLGSCSHSSDLQGLQACGITAVLNVSASCPNHF
           160       170       180       190       200       210   

        240       250       260       270       280       290      
pF1KB6 EGHYQYKCIPVEDNHKADISSWFMEAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLM
       :: ..:: ::::::. ..::.::.::: .:: ::.  :::::::::::::::::::::::
NP_004 EGLFRYKSIPVEDNQMVEISAWFQEAIGFIDWVKNSGGRVLVHCQAGISRSATICLAYLM
           220       230       240       250       260       270   

        300       310       320       330       340       350      
pF1KB6 MKKRVRLEEAFEFVKQRRSIISPNFSFMGQLLQFESQVLATSCAAEAASPSGPLRERGKT
       ...::::.:::.::::::..:::::::::::::::.:::                     
NP_004 QSRRVRLDEAFDFVKQRRGVISPNFSFMGQLLQFETQVLCH                   
           280       290       300       310                       

        360       370       380       390    
pF1KB6 PATPTSQFVFSFPVSVGVHSAPSSLPYLHSPITTSPSC

>>XP_016859035 (OMIM: 603068) PREDICTED: dual specificit  (342 aa)
 initn: 875 init1: 729 opt: 786  Z-score: 803.5  bits: 157.3 E(85289): 5.1e-38
Smith-Waterman score: 888; 44.7% identity (66.3% similar) in 365 aa overlap (4-335:3-340)

               10        20        30        40        50        60
pF1KB6 MVTMEELREMDCSVLKRLMNRDENGGGAGGSGSHGTLGLPSGGKCLLLDCRPFLAHSAGY
          .:  ::..:..:  :. ::                   . . ::::::::::    .
XP_016  MGLEAARELECAALGTLL-RDPR----------------EAERTLLLDCRPFLAFCRRH
                10         20                        30        40  

               70          80        90       100       110        
pF1KB6 ILGSVNVRCNTIVRRRAKG--SVSLEQILPAEEEVRARLRSGLYSAVIVYDERSPRAESL
       . ..  :  :...::::.:  .. :  .:: .. .:.::  :  . ..: :: :  .  :
XP_016 VRAARPVPWNALLRRRARGPPAAVLACLLP-DRALRTRLVRGELARAVVLDEGSASVAEL
             50        60        70         80        90       100 

      120       130                                      140       
pF1KB6 REDSTVSLVVQALRRN-------------------------------AERTDICLLKGGY
       : :: . ... :: ..                               :.:. . :: ::.
XP_016 RPDSPAHVLLAALLHETRAGPTAVYFLRGEQAGRPWPAPPDSSPAFPADRA-LPLLAGGF
             110       120       130       140       150        160

       150       160       170       180       190       200       
pF1KB6 ERFSSEYPEFCSKTKALAAIPPPVPPSATEPLDLGCSSCGTPLHDQGGPVEILPFLYLGS
       . :..  :..::.. :     : .::.. .    . :.  .:..::::::::::.:.:::
XP_016 DGFQGCCPDLCSEAPA-----PALPPTGDKT---SRSDSRAPVYDQGGPVEILPYLFLGS
              170            180          190       200       210  

       210       220       230       240       250       260       
pF1KB6 AYHAARRDMLDALGITALLNVSSDCPNHFEGHYQYKCIPVEDNHKADISSWFMEAIEYID
         :..  . :.: ::::.::::..::::::: ..:: ::::::. ..::.::.::: .::
XP_016 CSHSSDLQGLQACGITAVLNVSASCPNHFEGLFRYKSIPVEDNQMVEISAWFQEAIGFID
            220       230       240       250       260       270  

       270       280       290       300       310       320       
pF1KB6 AVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEFVKQRRSIISPNFSFMGQL
        ::.  :::::::::::::::::::::::...::::.:::.::::::..:::::::::::
XP_016 WVKNSGGRVLVHCQAGISRSATICLAYLMQSRRVRLDEAFDFVKQRRGVISPNFSFMGQL
            280       290       300       310       320       330  

       330       340       350       360       370       380       
pF1KB6 LQFESQVLATSCAAEAASPSGPLRERGKTPATPTSQFVFSFPVSVGVHSAPSSLPYLHSP
       ::::.:::                                                    
XP_016 LQFETQVLCH                                                  
            340                                                    

>>NP_009138 (OMIM: 608867) dual specificity protein phos  (482 aa)
 initn: 544 init1: 338 opt: 582  Z-score: 594.3  bits: 119.1 E(85289): 2.3e-26
Smith-Waterman score: 582; 34.0% identity (66.3% similar) in 297 aa overlap (39-331:167-459)

       10        20        30        40        50        60        
pF1KB6 EMDCSVLKRLMNRDENGGGAGGSGSHGTLGLPSGGKCLLLDCRPFLAHSAGYILGSVNVR
                                     ::: :  ...:::::. .. ..: :.:.. 
NP_009 VSGTPKQLASIKIIYPNDLAKKMTKCSKSHLPSQGP-VIIDCRPFMEYNKSHIQGAVHIN
        140       150       160       170        180       190     

        70         80        90       100       110       120      
pF1KB6 C-NTIVRRR-AKGSVSLEQILPAEEEVRARLRSGLYSAVIVYDERSPRAESLREDSTVSL
       : . : :::  .:.... ...  .:  .  ..  . . .::::: . .   .  .. . .
NP_009 CADKISRRRLQQGKITVLDLISCREG-KDSFKRIFSKEIIVYDENTNEPSRVMPSQPLHI
         200       210       220        230       240       250    

        130       140       150       160       170       180      
pF1KB6 VVQALRRNAERTDICLLKGGYERFSSEYPEFCSKTKALAAIPPPVPPSATEPLDLGCSSC
       :...:.:  :  .  .::::   :.... ..:...  :         ...    :     
NP_009 VLESLKR--EGKEPLVLKGGLSSFKQNHENLCDNSLQLQECREVGGGASAASSLLPQPIP
          260         270       280       290       300       310  

        190       200       210       220       230         240    
pF1KB6 GTPLHDQGGPVEILPFLYLGSAYHAARRDMLDALGITALLNVSSDCP-NHFE-GHYQYKC
        ::  ...  . :::::.::.   :   : .. :.:  ..::..  :  :.: : ..:: 
NP_009 TTPDIENAELTPILPFLFLGNEQDAQDLDTMQRLNIGYVINVTTHLPLYHYEKGLFNYKR
            320       330       340       350       360       370  

          250       260       270       280       290       300    
pF1KB6 IPVEDNHKADISSWFMEAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLE
       .:. :..: .. ..: ::.:.:. ...:   .:.:::::.:::::: .:::: . :. . 
NP_009 LPATDSNKQNLRQYFEEAFEFIEEAHQCGKGLLIHCQAGVSRSATIVIAYLMKHTRMTMT
            380       390       400       410       420       430  

          310       320       330       340       350       360    
pF1KB6 EAFEFVKQRRSIISPNFSFMGQLLQFESQVLATSCAAEAASPSGPLRERGKTPATPTSQF
       .:..::: .: :::::..::::::.::                                 
NP_009 DAYKFVKGKRPIISPNLNFMGQLLEFEEDLNNGVTPRILTPKLMGVETVV          
            440       450       460       470       480            

>>NP_001938 (OMIM: 602749) dual specificity protein phos  (419 aa)
 initn: 553 init1: 333 opt: 477  Z-score: 488.6  bits: 99.3 E(85289): 1.8e-20
Smith-Waterman score: 624; 34.4% identity (62.8% similar) in 366 aa overlap (24-345:37-397)

                      10        20        30        40             
pF1KB6        MVTMEELREMDCSVLKRLMNRDENGGGAGGSGSHGTLGLP-------------
                                     .:.:.:.... :. ..:             
NP_001 GPPARAHMSTSGAAAAGGTRAGSEPGAGSGSGAGTGAGAATGAGAMPCKSAEWLQEELEA
         10        20        30        40        50        60      

                50        60         70        80        90        
pF1KB6 -SGGKCLLLDCRPFLAHSAGYILGSVNVRC-NTIVRRRAKGSVSLEQILPAEEEVRARLR
        .:.. :::::::     ...:  ..:.   . ..::  ::.. ...:.: . . . :. 
NP_001 RGGASLLLLDCRPHELFESSHIETAINLAIPGLMLRRLRKGNLPIRSIIPNHAD-KERFA
         70        80        90       100       110       120      

      100        110         120       130       140       150     
pF1KB6 SGLYSA-VIVYDERSP--RAESLREDSTVSLVVQALRRNAERTDICLLKGGYERFSSEYP
       .   .: :..::: .   . :     :...:..: :: .. ..    :.::...:..:: 
NP_001 TRCKAATVLLYDEATAEWQPEPGAPASVLGLLLQKLRDDGCQAYY--LQGGFNKFQTEYS
         130       140       150       160       170         180   

         160       170       180                            190    
pF1KB6 EFCSKTKALAAIPPPVPPSATEPLDLG-------CS--------------SCGTPLHDQG
       : :  .   .. :   ::...  : ::       ::              : :.:. .. 
NP_001 EHCETNVDSSSSPSSSPPTSV--LGLGGLRISSDCSDGESDRELPSSATESDGSPVPSSQ
           190       200         210       220       230       240 

            200       210       220       230         240       250
pF1KB6 G--PVEILPFLYLGSAYHAARRDMLDALGITALLNVSSDCPNHFE--GHYQYKCIPVEDN
          ::.:::.:::: :  ..  :.:   ::  .:::. . :: ::  :.. :: ::. :.
NP_001 PAFPVQILPYLYLGCAKDSTNLDVLGKYGIKYILNVTPNLPNAFEHGGEFTYKQIPISDH
             250       260       270       280       290       300 

              260       270       280       290       300       310
pF1KB6 HKADISSWFMEAIEYIDAVKDCRGRVLVHCQAGISRSATICLAYLMMKKRVRLEEAFEFV
        . ..:..: ::: .:: ... .  ::::: ::::::.:. .::::.:  . :..:..::
NP_001 WSQNLSQFFPEAISFIDEARSKKCGVLVHCLAGISRSVTVTVAYLMQKMNLSLNDAYDFV
             310       320       330       340       350       360 

              320       330        340       350       360         
pF1KB6 KQRRSIISPNFSFMGQLLQFESQV-LATSCAAEAASPSGPLRERGKTPATPTSQFVFSFP
       :...: :::::.::::::.::  . :.. :  .:.:                        
NP_001 KRKKSNISPNFNFMGQLLDFERTLGLSSPCDNHASSEQLYFSTPTNHNLFPLNTLEST  
             370       380       390       400       410           

     370       380       390    
pF1KB6 VSVGVHSAPSSLPYLHSPITTSPSC

>>NP_001937 (OMIM: 602748,615269) dual specificity prote  (381 aa)
 initn: 570 init1: 318 opt: 472  Z-score: 484.1  bits: 98.4 E(85289): 3.2e-20
Smith-Waterman score: 589; 34.9% identity (62.9% similar) in 350 aa overlap (44-366:33-373)

            20        30        40        50        60        70   
pF1KB6 VLKRLMNRDENGGGAGGSGSHGTLGLPSGGKCLLLDCRPFLAHSAGYILGSVNVRCNTIV
                                     . ::.::::   . ...: ...::    :.
NP_001 DTLRPVPFASEMAISKTVAWLNEQLELGNERLLLMDCRPQELYESSHIESAINVAIPGIM
             10        20        30        40        50        60  

             80         90       100       110        120       130
pF1KB6 RRR-AKGSVSLEQILP-AEEEVRARLRSGLYSAVIVYDERSPR-AESLREDSTVSLVVQA
        ::  ::.. .. ..  .:.. :   : :  ..:..::: :    :.   .:...:... 
NP_001 LRRLQKGNLPVRALFTRGEDRDRFTRRCGT-DTVVLYDESSSDWNENTGGESVLGLLLKK
             70        80        90        100       110       120 

              140       150       160         170                  
pF1KB6 LRRNAERTDICLLKGGYERFSSEYPEFCSKT--KALAAIPPPVP------------PSAT
       :. .. :.    :.::. .:..:.   :  .   . ..  ::.:             :. 
NP_001 LKDEGCRA--FYLEGGFSKFQAEFSLHCETNLDGSCSSSSPPLPVLGLGGLRISSDSSSD
               130       140       150       160       170         

        180             190         200       210       220        
pF1KB6 EPLDL------GCSSCGTPLHDQGG--PVEILPFLYLGSAYHAARRDMLDALGITALLNV
          ::      . .: :.:: ..    ::::::::::: :  ..  :.:. .::  .:::
NP_001 IESDLDRDPNSATDSDGSPLSNSQPSFPVEILPFLYLGCAKDSTNLDVLEEFGIKYILNV
     180       190       200       210       220       230         

      230         240       250       260       270       280      
pF1KB6 SSDCPNHFE--GHYQYKCIPVEDNHKADISSWFMEAIEYIDAVKDCRGRVLVHCQAGISR
       . . :: ::  :...:: ::. :. . ..:..: ::: .:: ..     ::::: :::::
NP_001 TPNLPNLFENAGEFKYKQIPISDHWSQNLSQFFPEAISFIDEARGKNCGVLVHCLAGISR
     240       250       260       270       280       290         

        290       300       310       320       330       340      
pF1KB6 SATICLAYLMMKKRVRLEEAFEFVKQRRSIISPNFSFMGQLLQFESQVLATSCAAEAASP
       :.:. .::::.:  . ...:...::...: :::::.::::::.:: ..:. :   .   :
NP_001 SVTVTVAYLMQKLNLSMNDAYDIVKMKKSNISPNFNFMGQLLDFE-RTLGLSSPCDNRVP
     300       310       320       330       340        350        

        350       360       370       380       390    
pF1KB6 SGPLRERGKTPATPTSQFVFSFPVSVGVHSAPSSLPYLHSPITTSPSC
       .  :       .::..: :.                            
NP_001 AQQLYF-----TTPSNQNVYQVDSLQST                    
      360            370       380                     




394 residues in 1 query   sequences
60827320 residues in 85289 library sequences
 Tcomplib [36.3.4 Apr, 2011] (8 proc)
 start: Fri Nov  4 23:17:10 2016 done: Fri Nov  4 23:17:11 2016
 Total Scan time:  9.210 Total Display time:  0.010

Function used was FASTA [36.3.4 Apr, 2011]
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