FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6559, 373 aa 1>>>pF1KB6559 373 - 373 aa - 373 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 11.6771+/-0.000409; mu= -8.2770+/- 0.026 mean_var=542.4899+/-112.737, 0's: 0 Z-trim(125.7): 229 B-trim: 878 in 1/60 Lambda= 0.055065 statistics sampled from 49751 (50041) to 49751 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.839), E-opt: 0.2 (0.587), width: 16 Scan time: 7.190 The best scores are: opt bits E(85289) NP_060026 (OMIM: 607747) filamin-binding LIM prote ( 373) 2735 231.1 3.1e-60 XP_011539919 (OMIM: 607747) PREDICTED: filamin-bin ( 373) 2735 231.1 3.1e-60 XP_016857014 (OMIM: 607747) PREDICTED: filamin-bin ( 373) 2735 231.1 3.1e-60 XP_005245966 (OMIM: 607747) PREDICTED: filamin-bin ( 373) 2735 231.1 3.1e-60 XP_011539920 (OMIM: 607747) PREDICTED: filamin-bin ( 314) 2152 184.7 2.5e-46 XP_005245960 (OMIM: 607747) PREDICTED: filamin-bin ( 374) 2154 185.0 2.5e-46 XP_006710767 (OMIM: 607747) PREDICTED: filamin-bin ( 374) 2154 185.0 2.5e-46 XP_016857012 (OMIM: 607747) PREDICTED: filamin-bin ( 374) 2154 185.0 2.5e-46 XP_005245959 (OMIM: 607747) PREDICTED: filamin-bin ( 374) 2154 185.0 2.5e-46 XP_011539918 (OMIM: 607747) PREDICTED: filamin-bin ( 374) 2154 185.0 2.5e-46 NP_001019386 (OMIM: 607747) filamin-binding LIM pr ( 374) 2154 185.0 2.5e-46 XP_006710768 (OMIM: 607747) PREDICTED: filamin-bin ( 374) 2154 185.0 2.5e-46 XP_016857013 (OMIM: 607747) PREDICTED: filamin-bin ( 374) 2154 185.0 2.5e-46 XP_005245957 (OMIM: 607747) PREDICTED: filamin-bin ( 374) 2154 185.0 2.5e-46 XP_016857011 (OMIM: 607747) PREDICTED: filamin-bin ( 374) 2154 185.0 2.5e-46 XP_016857010 (OMIM: 607747) PREDICTED: filamin-bin ( 374) 2154 185.0 2.5e-46 XP_016857009 (OMIM: 607747) PREDICTED: filamin-bin ( 374) 2154 185.0 2.5e-46 XP_016857008 (OMIM: 607747) PREDICTED: filamin-bin ( 374) 2154 185.0 2.5e-46 XP_005245958 (OMIM: 607747) PREDICTED: filamin-bin ( 374) 2154 185.0 2.5e-46 XP_016857015 (OMIM: 607747) PREDICTED: filamin-bin ( 309) 2149 184.5 2.9e-46 NP_001019387 (OMIM: 607747) filamin-binding LIM pr ( 276) 1487 131.8 1.8e-30 XP_011514871 (OMIM: 602002) PREDICTED: zyxin isofo ( 541) 794 77.1 1e-13 NP_001010972 (OMIM: 602002) zyxin [Homo sapiens] ( 572) 794 77.1 1.1e-13 NP_003452 (OMIM: 602002) zyxin [Homo sapiens] ( 572) 794 77.1 1.1e-13 XP_016868076 (OMIM: 602002) PREDICTED: zyxin isofo ( 631) 794 77.2 1.2e-13 NP_003293 (OMIM: 602933) thyroid receptor-interact ( 476) 720 71.2 5.7e-12 NP_001161144 (OMIM: 600700) lipoma-preferred partn ( 465) 703 69.8 1.4e-11 XP_016861871 (OMIM: 600700) PREDICTED: lipoma-pref ( 449) 695 69.2 2.2e-11 XP_011511138 (OMIM: 600700) PREDICTED: lipoma-pref ( 449) 695 69.2 2.2e-11 XP_011511133 (OMIM: 600700) PREDICTED: lipoma-pref ( 612) 695 69.3 2.6e-11 XP_011511130 (OMIM: 600700) PREDICTED: lipoma-pref ( 612) 695 69.3 2.6e-11 NP_001161143 (OMIM: 600700) lipoma-preferred partn ( 612) 695 69.3 2.6e-11 XP_016861868 (OMIM: 600700) PREDICTED: lipoma-pref ( 612) 695 69.3 2.6e-11 XP_011511129 (OMIM: 600700) PREDICTED: lipoma-pref ( 612) 695 69.3 2.6e-11 XP_011511135 (OMIM: 600700) PREDICTED: lipoma-pref ( 612) 695 69.3 2.6e-11 XP_011511136 (OMIM: 600700) PREDICTED: lipoma-pref ( 612) 695 69.3 2.6e-11 XP_011511122 (OMIM: 600700) PREDICTED: lipoma-pref ( 612) 695 69.3 2.6e-11 XP_016861866 (OMIM: 600700) PREDICTED: lipoma-pref ( 612) 695 69.3 2.6e-11 NP_005569 (OMIM: 600700) lipoma-preferred partner ( 612) 695 69.3 2.6e-11 XP_005247510 (OMIM: 600700) PREDICTED: lipoma-pref ( 612) 695 69.3 2.6e-11 XP_005247507 (OMIM: 600700) PREDICTED: lipoma-pref ( 612) 695 69.3 2.6e-11 XP_005247508 (OMIM: 600700) PREDICTED: lipoma-pref ( 612) 695 69.3 2.6e-11 XP_005247503 (OMIM: 600700) PREDICTED: lipoma-pref ( 612) 695 69.3 2.6e-11 XP_016861867 (OMIM: 600700) PREDICTED: lipoma-pref ( 612) 695 69.3 2.6e-11 XP_016861869 (OMIM: 600700) PREDICTED: lipoma-pref ( 612) 695 69.3 2.6e-11 XP_011511125 (OMIM: 600700) PREDICTED: lipoma-pref ( 637) 695 69.3 2.7e-11 NP_055055 (OMIM: 604543) LIM domain-containing pro ( 676) 661 66.7 1.8e-10 NP_116265 (OMIM: 609066) LIM domain-containing pro ( 538) 622 63.5 1.4e-09 NP_001073905 (OMIM: 614790) Wilms tumor protein 1- ( 430) 617 62.9 1.5e-09 XP_011524754 (OMIM: 614790) PREDICTED: Wilms tumor ( 472) 519 55.2 3.6e-07 >>NP_060026 (OMIM: 607747) filamin-binding LIM protein 1 (373 aa) initn: 2735 init1: 2735 opt: 2735 Z-score: 1202.3 bits: 231.1 E(85289): 3.1e-60 Smith-Waterman score: 2735; 99.7% identity (99.7% similar) in 373 aa overlap (1-373:1-373) 10 20 30 40 50 60 pF1KB6 MASKPEKRVASSVFITLAPPRRDVAVAEEVRQAVCEARRGRPWEAPAPMKTPEAGLAGRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 MASKPEKRVASSVFITLAPPRRDVAVAEEVRQAVCEARRGRPWEAPAPMKTPEAGLAGRP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 SPWTTPGRAAATVPAAPMQLFNGGCPPPPPVLDGEDVLPDLDLLPPPPPPPPVLLPSEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 SPWTTPGRAAATVPAAPMQLFNGGCPPPPPVLDGEDVLPDLDLLPPPPPPPPVLLPSEEE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 APAPMGASLIADLEQLHLSPPPPPPQAPAEGPSVQPGPLRPMEEELPPPPAEPVEKGAST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 APAPMGASLIADLEQLHLSPPPPPPQAPAEGPSVQPGPLRPMEEELPPPPAEPVEKGAST 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 DICAFCHKTVFPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTL :::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 DICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 ERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 ERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 PVCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLFC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_060 PVCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLFC 310 320 330 340 350 360 370 pF1KB6 KPCHVKRSAAGCC ::::::::::::: NP_060 KPCHVKRSAAGCC 370 >>XP_011539919 (OMIM: 607747) PREDICTED: filamin-binding (373 aa) initn: 2735 init1: 2735 opt: 2735 Z-score: 1202.3 bits: 231.1 E(85289): 3.1e-60 Smith-Waterman score: 2735; 99.7% identity (99.7% similar) in 373 aa overlap (1-373:1-373) 10 20 30 40 50 60 pF1KB6 MASKPEKRVASSVFITLAPPRRDVAVAEEVRQAVCEARRGRPWEAPAPMKTPEAGLAGRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MASKPEKRVASSVFITLAPPRRDVAVAEEVRQAVCEARRGRPWEAPAPMKTPEAGLAGRP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 SPWTTPGRAAATVPAAPMQLFNGGCPPPPPVLDGEDVLPDLDLLPPPPPPPPVLLPSEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPWTTPGRAAATVPAAPMQLFNGGCPPPPPVLDGEDVLPDLDLLPPPPPPPPVLLPSEEE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 APAPMGASLIADLEQLHLSPPPPPPQAPAEGPSVQPGPLRPMEEELPPPPAEPVEKGAST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 APAPMGASLIADLEQLHLSPPPPPPQAPAEGPSVQPGPLRPMEEELPPPPAEPVEKGAST 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 DICAFCHKTVFPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTL :::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 ERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 PVCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLFC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 PVCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLFC 310 320 330 340 350 360 370 pF1KB6 KPCHVKRSAAGCC ::::::::::::: XP_011 KPCHVKRSAAGCC 370 >>XP_016857014 (OMIM: 607747) PREDICTED: filamin-binding (373 aa) initn: 2735 init1: 2735 opt: 2735 Z-score: 1202.3 bits: 231.1 E(85289): 3.1e-60 Smith-Waterman score: 2735; 99.7% identity (99.7% similar) in 373 aa overlap (1-373:1-373) 10 20 30 40 50 60 pF1KB6 MASKPEKRVASSVFITLAPPRRDVAVAEEVRQAVCEARRGRPWEAPAPMKTPEAGLAGRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MASKPEKRVASSVFITLAPPRRDVAVAEEVRQAVCEARRGRPWEAPAPMKTPEAGLAGRP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 SPWTTPGRAAATVPAAPMQLFNGGCPPPPPVLDGEDVLPDLDLLPPPPPPPPVLLPSEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SPWTTPGRAAATVPAAPMQLFNGGCPPPPPVLDGEDVLPDLDLLPPPPPPPPVLLPSEEE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 APAPMGASLIADLEQLHLSPPPPPPQAPAEGPSVQPGPLRPMEEELPPPPAEPVEKGAST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 APAPMGASLIADLEQLHLSPPPPPPQAPAEGPSVQPGPLRPMEEELPPPPAEPVEKGAST 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 DICAFCHKTVFPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTL :::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 ERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 PVCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLFC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 PVCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLFC 310 320 330 340 350 360 370 pF1KB6 KPCHVKRSAAGCC ::::::::::::: XP_016 KPCHVKRSAAGCC 370 >>XP_005245966 (OMIM: 607747) PREDICTED: filamin-binding (373 aa) initn: 2735 init1: 2735 opt: 2735 Z-score: 1202.3 bits: 231.1 E(85289): 3.1e-60 Smith-Waterman score: 2735; 99.7% identity (99.7% similar) in 373 aa overlap (1-373:1-373) 10 20 30 40 50 60 pF1KB6 MASKPEKRVASSVFITLAPPRRDVAVAEEVRQAVCEARRGRPWEAPAPMKTPEAGLAGRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MASKPEKRVASSVFITLAPPRRDVAVAEEVRQAVCEARRGRPWEAPAPMKTPEAGLAGRP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 SPWTTPGRAAATVPAAPMQLFNGGCPPPPPVLDGEDVLPDLDLLPPPPPPPPVLLPSEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SPWTTPGRAAATVPAAPMQLFNGGCPPPPPVLDGEDVLPDLDLLPPPPPPPPVLLPSEEE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 APAPMGASLIADLEQLHLSPPPPPPQAPAEGPSVQPGPLRPMEEELPPPPAEPVEKGAST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 APAPMGASLIADLEQLHLSPPPPPPQAPAEGPSVQPGPLRPMEEELPPPPAEPVEKGAST 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 DICAFCHKTVFPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTL :::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 ERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFA :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFA 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 PVCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLFC :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 PVCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLFC 310 320 330 340 350 360 370 pF1KB6 KPCHVKRSAAGCC ::::::::::::: XP_005 KPCHVKRSAAGCC 370 >>XP_011539920 (OMIM: 607747) PREDICTED: filamin-binding (314 aa) initn: 2146 init1: 2146 opt: 2152 Z-score: 952.8 bits: 184.7 E(85289): 2.5e-46 Smith-Waterman score: 2152; 98.0% identity (98.3% similar) in 303 aa overlap (1-303:1-303) 10 20 30 40 50 60 pF1KB6 MASKPEKRVASSVFITLAPPRRDVAVAEEVRQAVCEARRGRPWEAPAPMKTPEAGLAGRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MASKPEKRVASSVFITLAPPRRDVAVAEEVRQAVCEARRGRPWEAPAPMKTPEAGLAGRP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 SPWTTPGRAAATVPAAPMQLFNGGCPPPPPVLDGEDVLPDLDLLPPPPPPPPVLLPSEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPWTTPGRAAATVPAAPMQLFNGGCPPPPPVLDGEDVLPDLDLLPPPPPPPPVLLPSEEE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 APAPMGASLIADLEQLHLSPPPPPPQAPAEGPSVQPGPLRPMEEELPPPPAEPVEKGAST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 APAPMGASLIADLEQLHLSPPPPPPQAPAEGPSVQPGPLRPMEEELPPPPAEPVEKGAST 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 DICAFCHKTVFPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTL :::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 ERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFA ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: . XP_011 ERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRTAG 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 PVCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLFC : XP_011 SSCLSSPRTKAATP 310 >>XP_005245960 (OMIM: 607747) PREDICTED: filamin-binding (374 aa) initn: 2146 init1: 2146 opt: 2154 Z-score: 952.8 bits: 185.0 E(85289): 2.5e-46 Smith-Waterman score: 2154; 97.7% identity (98.4% similar) in 304 aa overlap (1-304:1-304) 10 20 30 40 50 60 pF1KB6 MASKPEKRVASSVFITLAPPRRDVAVAEEVRQAVCEARRGRPWEAPAPMKTPEAGLAGRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MASKPEKRVASSVFITLAPPRRDVAVAEEVRQAVCEARRGRPWEAPAPMKTPEAGLAGRP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 SPWTTPGRAAATVPAAPMQLFNGGCPPPPPVLDGEDVLPDLDLLPPPPPPPPVLLPSEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SPWTTPGRAAATVPAAPMQLFNGGCPPPPPVLDGEDVLPDLDLLPPPPPPPPVLLPSEEE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 APAPMGASLIADLEQLHLSPPPPPPQAPAEGPSVQPGPLRPMEEELPPPPAEPVEKGAST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 APAPMGASLIADLEQLHLSPPPPPPQAPAEGPSVQPGPLRPMEEELPPPPAEPVEKGAST 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 DICAFCHKTVFPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTL :::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 ERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFA ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRYEK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 PVCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLFC .:. XP_005 GLCTGWGAGTGRDPSRVKELSLSPGCWARVSCLLVYYKEYYRAGLGAVAHACNPSTLGGR 310 320 330 340 350 360 >>XP_006710767 (OMIM: 607747) PREDICTED: filamin-binding (374 aa) initn: 2146 init1: 2146 opt: 2154 Z-score: 952.8 bits: 185.0 E(85289): 2.5e-46 Smith-Waterman score: 2154; 97.7% identity (98.4% similar) in 304 aa overlap (1-304:1-304) 10 20 30 40 50 60 pF1KB6 MASKPEKRVASSVFITLAPPRRDVAVAEEVRQAVCEARRGRPWEAPAPMKTPEAGLAGRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 MASKPEKRVASSVFITLAPPRRDVAVAEEVRQAVCEARRGRPWEAPAPMKTPEAGLAGRP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 SPWTTPGRAAATVPAAPMQLFNGGCPPPPPVLDGEDVLPDLDLLPPPPPPPPVLLPSEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 SPWTTPGRAAATVPAAPMQLFNGGCPPPPPVLDGEDVLPDLDLLPPPPPPPPVLLPSEEE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 APAPMGASLIADLEQLHLSPPPPPPQAPAEGPSVQPGPLRPMEEELPPPPAEPVEKGAST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 APAPMGASLIADLEQLHLSPPPPPPQAPAEGPSVQPGPLRPMEEELPPPPAEPVEKGAST 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 DICAFCHKTVFPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTL :::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 DICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 ERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFA ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_006 ERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRYEK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 PVCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLFC .:. XP_006 GLCTGWGAGTGRDPSRVKELSLSPGCWARVSCLLVYYKEYYRAGLGAVAHACNPSTLGGR 310 320 330 340 350 360 >>XP_016857012 (OMIM: 607747) PREDICTED: filamin-binding (374 aa) initn: 2146 init1: 2146 opt: 2154 Z-score: 952.8 bits: 185.0 E(85289): 2.5e-46 Smith-Waterman score: 2154; 97.7% identity (98.4% similar) in 304 aa overlap (1-304:1-304) 10 20 30 40 50 60 pF1KB6 MASKPEKRVASSVFITLAPPRRDVAVAEEVRQAVCEARRGRPWEAPAPMKTPEAGLAGRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 MASKPEKRVASSVFITLAPPRRDVAVAEEVRQAVCEARRGRPWEAPAPMKTPEAGLAGRP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 SPWTTPGRAAATVPAAPMQLFNGGCPPPPPVLDGEDVLPDLDLLPPPPPPPPVLLPSEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 SPWTTPGRAAATVPAAPMQLFNGGCPPPPPVLDGEDVLPDLDLLPPPPPPPPVLLPSEEE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 APAPMGASLIADLEQLHLSPPPPPPQAPAEGPSVQPGPLRPMEEELPPPPAEPVEKGAST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 APAPMGASLIADLEQLHLSPPPPPPQAPAEGPSVQPGPLRPMEEELPPPPAEPVEKGAST 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 DICAFCHKTVFPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTL :::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 DICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 ERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFA ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_016 ERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRYEK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 PVCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLFC .:. XP_016 GLCTGWGAGTGRDPSRVKELSLSPGCWARVSCLLVYYKEYYRAGLGAVAHACNPSTLGGR 310 320 330 340 350 360 >>XP_005245959 (OMIM: 607747) PREDICTED: filamin-binding (374 aa) initn: 2146 init1: 2146 opt: 2154 Z-score: 952.8 bits: 185.0 E(85289): 2.5e-46 Smith-Waterman score: 2154; 97.7% identity (98.4% similar) in 304 aa overlap (1-304:1-304) 10 20 30 40 50 60 pF1KB6 MASKPEKRVASSVFITLAPPRRDVAVAEEVRQAVCEARRGRPWEAPAPMKTPEAGLAGRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 MASKPEKRVASSVFITLAPPRRDVAVAEEVRQAVCEARRGRPWEAPAPMKTPEAGLAGRP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 SPWTTPGRAAATVPAAPMQLFNGGCPPPPPVLDGEDVLPDLDLLPPPPPPPPVLLPSEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 SPWTTPGRAAATVPAAPMQLFNGGCPPPPPVLDGEDVLPDLDLLPPPPPPPPVLLPSEEE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 APAPMGASLIADLEQLHLSPPPPPPQAPAEGPSVQPGPLRPMEEELPPPPAEPVEKGAST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 APAPMGASLIADLEQLHLSPPPPPPQAPAEGPSVQPGPLRPMEEELPPPPAEPVEKGAST 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 DICAFCHKTVFPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTL :::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 DICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 ERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFA ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_005 ERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRYEK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 PVCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLFC .:. XP_005 GLCTGWGAGTGRDPSRVKELSLSPGCWARVSCLLVYYKEYYRAGLGAVAHACNPSTLGGR 310 320 330 340 350 360 >>XP_011539918 (OMIM: 607747) PREDICTED: filamin-binding (374 aa) initn: 2146 init1: 2146 opt: 2154 Z-score: 952.8 bits: 185.0 E(85289): 2.5e-46 Smith-Waterman score: 2154; 97.7% identity (98.4% similar) in 304 aa overlap (1-304:1-304) 10 20 30 40 50 60 pF1KB6 MASKPEKRVASSVFITLAPPRRDVAVAEEVRQAVCEARRGRPWEAPAPMKTPEAGLAGRP :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 MASKPEKRVASSVFITLAPPRRDVAVAEEVRQAVCEARRGRPWEAPAPMKTPEAGLAGRP 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 SPWTTPGRAAATVPAAPMQLFNGGCPPPPPVLDGEDVLPDLDLLPPPPPPPPVLLPSEEE :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 SPWTTPGRAAATVPAAPMQLFNGGCPPPPPVLDGEDVLPDLDLLPPPPPPPPVLLPSEEE 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 APAPMGASLIADLEQLHLSPPPPPPQAPAEGPSVQPGPLRPMEEELPPPPAEPVEKGAST :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 APAPMGASLIADLEQLHLSPPPPPPQAPAEGPSVQPGPLRPMEEELPPPPAEPVEKGAST 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 DICAFCHKTVFPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTL :::::::::: ::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 DICAFCHKTVSPRELAVEAMKRQYHAQCFTCRTCRRQLAGQSFYQKDGRPLCEPCYQDTL 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 ERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRKFA ::::::::::::::::::::::::::::::::::::::::::::::::::::::::: XP_011 ERCGKCGEVVRDHIIRALGQAFHPSCFTCVTCARCIGDESFALGSQNEVYCLDDFYRYEK 250 260 270 280 290 300 310 320 330 340 350 360 pF1KB6 PVCSICENPIIPRDGKDAFKIECMGRNFHENCYRCEDCRILLSVEPTDQGCYPLNNHLFC .:. XP_011 GLCTGWGAGTGRDPSRVKELSLSPGCWARVSCLLVYYKEYYRAGLGAVAHACNPSTLGGR 310 320 330 340 350 360 373 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Fri Nov 4 23:19:29 2016 done: Fri Nov 4 23:19:30 2016 Total Scan time: 7.190 Total Display time: 0.000 Function used was FASTA [36.3.4 Apr, 2011]