FASTA searches a protein or DNA sequence data bank 36.3.4 Apr, 2011 Please cite: W.R. Pearson & D.J. Lipman PNAS (1988) 85:2444-2448 Query: pF1KB6560, 342 aa 1>>>pF1KB6560 342 - 342 aa - 342 aa Library: /omim/omim.rfq.tfa 60827320 residues in 85289 sequences Statistics: Expectation_n fit: rho(ln(x))= 7.3577+/-0.00033; mu= 7.0379+/- 0.021 mean_var=136.1637+/-27.380, 0's: 0 Z-trim(118.9): 197 B-trim: 45 in 1/55 Lambda= 0.109912 statistics sampled from 32192 (32415) to 32192 sequences Algorithm: FASTA (3.7 Nov 2010) [optimized] Parameters: BL50 matrix (15:-5), open/ext: -10/-2 ktup: 2, E-join: 1 (0.735), E-opt: 0.2 (0.38), width: 16 Scan time: 8.780 The best scores are: opt bits E(85289) NP_001074239 (OMIM: 604945) killer cell immunoglob ( 342) 2369 386.8 3.7e-107 NP_001074241 (OMIM: 604945) killer cell immunoglob ( 273) 1666 275.3 1.1e-73 NP_002246 (OMIM: 604945) killer cell immunoglobuli ( 377) 1666 275.3 1.4e-73 NP_065396 (OMIM: 605305) killer cell immunoglobuli ( 375) 1298 217.0 5.2e-56 XP_016885757 (OMIM: 615727) PREDICTED: killer cell ( 375) 1292 216.0 1e-55 XP_016885761 (OMIM: 615727) PREDICTED: killer cell ( 375) 1284 214.8 2.4e-55 XP_016885731 (OMIM: 615727) PREDICTED: killer cell ( 375) 1284 214.8 2.4e-55 NP_001018091 (OMIM: 615727) killer cell immunoglob ( 375) 1280 214.1 3.8e-55 XP_016885768 (OMIM: 615727) PREDICTED: killer cell ( 386) 1262 211.3 2.8e-54 XP_011525242 (OMIM: 604947) PREDICTED: killer cell ( 420) 1232 206.6 8.1e-53 XP_016885766 (OMIM: 615727) PREDICTED: killer cell ( 363) 1215 203.8 4.7e-52 XP_016885767 (OMIM: 604956) PREDICTED: LOW QUALITY ( 375) 1213 203.5 6e-52 NP_036446 (OMIM: 604955) killer cell immunoglobuli ( 304) 945 161.0 3.1e-39 XP_016882272 (OMIM: 604936) PREDICTED: killer cell ( 253) 927 158.1 1.9e-38 XP_016885735 (OMIM: 604937) PREDICTED: killer cell ( 374) 915 156.3 1e-37 XP_016885759 (OMIM: 604937) PREDICTED: killer cell ( 374) 915 156.3 1e-37 NP_036444 (OMIM: 604953) killer cell immunoglobuli ( 304) 913 155.9 1.1e-37 XP_016885764 (OMIM: 604953) PREDICTED: killer cell ( 304) 913 155.9 1.1e-37 NP_001278624 (OMIM: 604953) killer cell immunoglob ( 338) 913 155.9 1.1e-37 XP_016885734 (OMIM: 604937) PREDICTED: killer cell ( 348) 913 155.9 1.2e-37 XP_016885758 (OMIM: 604937) PREDICTED: killer cell ( 348) 913 155.9 1.2e-37 NP_055034 (OMIM: 604937) killer cell immunoglobuli ( 348) 913 155.9 1.2e-37 NP_055033 (OMIM: 604936) killer cell immunoglobuli ( 348) 911 155.6 1.5e-37 NP_056952 (OMIM: 604938) killer cell immunoglobuli ( 341) 903 154.3 3.5e-37 NP_055327 (OMIM: 604952) killer cell immunoglobuli ( 304) 894 152.9 8.5e-37 XP_016885782 (OMIM: 604936) PREDICTED: killer cell ( 330) 890 152.3 1.4e-36 XP_011546672 (OMIM: 604936) PREDICTED: killer cell ( 304) 888 151.9 1.6e-36 NP_036445 (OMIM: 604954) killer cell immunoglobuli ( 304) 886 151.6 2e-36 XP_016885760 (OMIM: 604954) PREDICTED: LOW QUALITY ( 360) 886 151.6 2.3e-36 XP_016885770 (OMIM: 604956) PREDICTED: killer cell ( 304) 883 151.1 2.8e-36 XP_016885769 (OMIM: 604956) PREDICTED: killer cell ( 304) 882 151.0 3.2e-36 NP_703144 (OMIM: 610095) killer cell immunoglobuli ( 410) 877 150.3 7e-36 NP_055328 (OMIM: 604956) killer cell immunoglobuli ( 304) 867 148.6 1.7e-35 XP_016885763 (OMIM: 604946,609423) PREDICTED: kill ( 397) 849 145.8 1.5e-34 XP_016882273 (OMIM: 604947) PREDICTED: killer cell ( 342) 845 145.1 2e-34 NP_001229796 (OMIM: 604947) killer cell immunoglob ( 438) 846 145.4 2.2e-34 NP_006728 (OMIM: 604947) killer cell immunoglobuli ( 455) 845 145.2 2.6e-34 NP_001278630 (OMIM: 604953) killer cell immunoglob ( 287) 828 142.4 1.1e-33 NP_001309097 (OMIM: 604946,609423) killer cell imm ( 444) 830 142.8 1.3e-33 NP_037421 (OMIM: 604946,609423) killer cell immuno ( 444) 830 142.8 1.3e-33 XP_011525241 (OMIM: 604936) PREDICTED: killer cell ( 235) 801 138.1 1.9e-32 XP_016885732 (OMIM: 604954) PREDICTED: LOW QUALITY ( 454) 804 138.7 2.3e-32 XP_016882271 (OMIM: 604936) PREDICTED: killer cell ( 295) 799 137.8 2.8e-32 XP_011546673 (OMIM: 604936) PREDICTED: killer cell ( 235) 783 135.2 1.4e-31 XP_016885733 (OMIM: 604956) PREDICTED: LOW QUALITY ( 541) 786 135.9 1.9e-31 XP_016885771 (OMIM: 604956) PREDICTED: LOW QUALITY ( 541) 786 135.9 1.9e-31 XP_016885756 (OMIM: 604956) PREDICTED: LOW QUALITY ( 541) 786 135.9 1.9e-31 XP_016885783 (OMIM: 604936) PREDICTED: killer cell ( 277) 778 134.4 2.7e-31 NP_001278625 (OMIM: 604953) killer cell immunoglob ( 204) 655 114.9 1.6e-25 XP_011524692 (OMIM: 604812) PREDICTED: leukocyte i ( 366) 516 93.0 1.1e-18 >>NP_001074239 (OMIM: 604945) killer cell immunoglobulin (342 aa) initn: 2369 init1: 2369 opt: 2369 Z-score: 2044.9 bits: 386.8 E(85289): 3.7e-107 Smith-Waterman score: 2369; 99.4% identity (99.7% similar) in 342 aa overlap (1-342:1-342) 10 20 30 40 50 60 pF1KB6 MSMSPTVIILACLGFFLDQSVWAHVGGQDKPFCSAWPSAVVPQGGHVTLRCHYRRGFNIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSMSPTVIILACLGFFLDQSVWAHVGGQDKPFCSAWPSAVVPQGGHVTLRCHYRRGFNIF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 TLYKKDGVPVPELYNRIFWNSFLISPVTPAHAGTYRCRGFHPHSPTEWSAPSNPLVIMVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TLYKKDGVPVPELYNRIFWNSFLISPVTPAHAGTYRCRGFHPHSPTEWSAPSNPLVIMVT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 GLYEKPSLTARPGPTVRTGENVTLSCSSQSSFDIYHLSREGEAHELRLPAVPSINGTFQA :::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::: NP_001 GLYEKPSLTARPGPTVRAGENVTLSCSSQSSFDIYHLSREGEAHELRLPAVPSINGTFQA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 DFPLGPATHGETYRCFGSFHGSPYEWSDASDPLPVSVTGNPSSSWPSPTEPSFKTDAAVM :::::::::::::::::::::::::::: ::::::::::::::::::::::::::::::: NP_001 DFPLGPATHGETYRCFGSFHGSPYEWSDPSDPLPVSVTGNPSSSWPSPTEPSFKTDAAVM 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 NQEPAGHRTVNREDSDEQDPQEVTYAQLDHCIFTQRKITGPSQRSKRPSTDTSVCIELPN :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 NQEPAGHRTVNREDSDEQDPQEVTYAQLDHCIFTQRKITGPSQRSKRPSTDTSVCIELPN 250 260 270 280 290 300 310 320 330 340 pF1KB6 AEPRALSPAHEHHSQALMGSSRETTALSQTQLASSNVPAAGI :::::::::::::::::::::::::::::::::::::::::: NP_001 AEPRALSPAHEHHSQALMGSSRETTALSQTQLASSNVPAAGI 310 320 330 340 >>NP_001074241 (OMIM: 604945) killer cell immunoglobulin (273 aa) initn: 1775 init1: 1666 opt: 1666 Z-score: 1443.9 bits: 275.3 E(85289): 1.1e-73 Smith-Waterman score: 1666; 98.3% identity (98.7% similar) in 238 aa overlap (1-238:1-238) 10 20 30 40 50 60 pF1KB6 MSMSPTVIILACLGFFLDQSVWAHVGGQDKPFCSAWPSAVVPQGGHVTLRCHYRRGFNIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 MSMSPTVIILACLGFFLDQSVWAHVGGQDKPFCSAWPSAVVPQGGHVTLRCHYRRGFNIF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 TLYKKDGVPVPELYNRIFWNSFLISPVTPAHAGTYRCRGFHPHSPTEWSAPSNPLVIMVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_001 TLYKKDGVPVPELYNRIFWNSFLISPVTPAHAGTYRCRGFHPHSPTEWSAPSNPLVIMVT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 GLYEKPSLTARPGPTVRTGENVTLSCSSQSSFDIYHLSREGEAHELRLPAVPSINGTFQA :::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::: NP_001 GLYEKPSLTARPGPTVRAGENVTLSCSSQSSFDIYHLSREGEAHELRLPAVPSINGTFQA 130 140 150 160 170 180 190 200 210 220 230 240 pF1KB6 DFPLGPATHGETYRCFGSFHGSPYEWSDASDPLPVSVTGNPSSSWPSPTEPSFKTDAAVM :::::::::::::::::::::::::::: :::::::::::::::::::::::::: : NP_001 DFPLGPATHGETYRCFGSFHGSPYEWSDPSDPLPVSVTGNPSSSWPSPTEPSFKTGIARH 190 200 210 220 230 240 250 260 270 280 290 300 pF1KB6 NQEPAGHRTVNREDSDEQDPQEVTYAQLDHCIFTQRKITGPSQRSKRPSTDTSVCIELPN NP_001 LHAVIRYSVAIILFTILPFFLLHRWCSKKKMLL 250 260 270 >>NP_002246 (OMIM: 604945) killer cell immunoglobulin-li (377 aa) initn: 1775 init1: 1666 opt: 1666 Z-score: 1441.8 bits: 275.3 E(85289): 1.4e-73 Smith-Waterman score: 2265; 89.8% identity (90.4% similar) in 374 aa overlap (1-339:1-374) 10 20 30 40 50 60 pF1KB6 MSMSPTVIILACLGFFLDQSVWAHVGGQDKPFCSAWPSAVVPQGGHVTLRCHYRRGFNIF :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 MSMSPTVIILACLGFFLDQSVWAHVGGQDKPFCSAWPSAVVPQGGHVTLRCHYRRGFNIF 10 20 30 40 50 60 70 80 90 100 110 120 pF1KB6 TLYKKDGVPVPELYNRIFWNSFLISPVTPAHAGTYRCRGFHPHSPTEWSAPSNPLVIMVT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 TLYKKDGVPVPELYNRIFWNSFLISPVTPAHAGTYRCRGFHPHSPTEWSAPSNPLVIMVT 70 80 90 100 110 120 130 140 150 160 170 180 pF1KB6 GLYEKPSLTARPGPTVRTGENVTLSCSSQSSFDIYHLSREGEAHELRLPAVPSINGTFQA :::::::::::::::::.:::::::::::::::::::::::::::::::::::::::::: NP_002 GLYEKPSLTARPGPTVRAGENVTLSCSSQSSFDIYHLSREGEAHELRLPAVPSINGTFQA 130 140 150 160 170 180 190 200 210 220 230 pF1KB6 DFPLGPATHGETYRCFGSFHGSPYEWSDASDPLPVSVTGNPSSSWPSPTEPSFKT----- :::::::::::::::::::::::::::: :::::::::::::::::::::::::: NP_002 DFPLGPATHGETYRCFGSFHGSPYEWSDPSDPLPVSVTGNPSSSWPSPTEPSFKTGIARH 190 200 210 220 230 240 240 250 260 pF1KB6 ------------------------------DAAVMNQEPAGHRTVNREDSDEQDPQEVTY .::::::::::::::::::::::::::::: NP_002 LHAVIRYSVAIILFTILPFFLLHRWCSKKKNAAVMNQEPAGHRTVNREDSDEQDPQEVTY 250 260 270 280 290 300 270 280 290 300 310 320 pF1KB6 AQLDHCIFTQRKITGPSQRSKRPSTDTSVCIELPNAEPRALSPAHEHHSQALMGSSRETT :::::::::::::::::::::::::::::::::::::::::::::::::::::::::::: NP_002 AQLDHCIFTQRKITGPSQRSKRPSTDTSVCIELPNAEPRALSPAHEHHSQALMGSSRETT 310 320 330 340 350 360 330 340 pF1KB6 ALSQTQLASSNVPAAGI :::::::::::::: NP_002 ALSQTQLASSNVPAAGI 370 >>NP_065396 (OMIM: 605305) killer cell immunoglobulin-li (375 aa) initn: 1298 init1: 1298 opt: 1298 Z-score: 1126.5 bits: 217.0 E(85289): 5.2e-56 Smith-Waterman score: 1773; 71.8% identity (82.8% similar) in 372 aa overlap (3-339:1-372) 10 20 30 40 50 60 pF1KB6 MSMSPTVIILACLGFFLDQSVWAHVGGQDKPFCSAWPSAVVPQGGHVTLRCHYRRGFNIF :: :: .::.:::: :..:.: ::::::. :::::::::.:::::: :. : ::.:: NP_065 MSLMVISMACVGFFLLQGAWTHEGGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIF 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 TLYKKDGVPVPELYNRIFWNSFLISPVTPAHAGTYRCRGFHPHSPTEWSAPSNPLVIMVT .:::.::::::::::.:::.:.:..:::::::::::::: ::.:: :::::::::::.:: NP_065 SLYKEDGVPVPELYNKIFWKSILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVIVVT 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 GLYEKPSLTARPGPTVRTGENVTLSCSSQSSFDIYHLSREGEAHELRLPAVPSINGTFQA ::. ::::.:.:::::::::::::::::.::::.:::::::.::: :::::::.:::::: NP_065 GLFGKPSLSAQPGPTVRTGENVTLSCSSRSSFDMYHLSREGRAHEPRLPAVPSVNGTFQA 120 130 140 150 160 170 190 200 210 220 230 pF1KB6 DFPLGPATHGETYRCFGSFHGSPYEWSDASDPLPVSVTGNPSSSWPSPTEPSFKT----- :::::::::: :: ::::.: ::::::: :::: :::::: ::: :::::: :: NP_065 DFPLGPATHGGTYTCFGSLHDSPYEWSDPSDPLLVSVTGNSSSSSSSPTEPSSKTGIRRH 180 190 200 210 220 230 240 250 260 pF1KB6 ------------------------------DAAVMNQEPAGHRTVNREDSDEQDPQEVTY .::::.::::: :::::::::.:::::::: NP_065 LHILIGTSVAIILFIILFFFLLHCCCSNKKNAAVMDQEPAGDRTVNREDSDDQDPQEVTY 240 250 260 270 280 290 270 280 290 300 310 320 pF1KB6 AQLDHCIFTQRKITGPSQRSKRPSTDTSVCIELPNAEPRALSPAHEHHSQALMGSSRETT ::::::.::: :::.:::: : : :::.. .:::::.::.:::::.:::::: ::::::: NP_065 AQLDHCVFTQTKITSPSQRPKTPPTDTTMYMELPNAKPRSLSPAHKHHSQALRGSSRETT 300 310 320 330 340 350 330 340 pF1KB6 ALSQTQLASSNVPAAGI ::::...:::.::: NP_065 ALSQNRVASSHVPAAGI 360 370 >>XP_016885757 (OMIM: 615727) PREDICTED: killer cell imm (375 aa) initn: 1292 init1: 1292 opt: 1292 Z-score: 1121.4 bits: 216.0 E(85289): 1e-55 Smith-Waterman score: 1767; 71.2% identity (82.8% similar) in 372 aa overlap (3-339:1-372) 10 20 30 40 50 60 pF1KB6 MSMSPTVIILACLGFFLDQSVWAHVGGQDKPFCSAWPSAVVPQGGHVTLRCHYRRGFNIF :: :. .::.:::: :..:.: ::::::. :::::.:::.:::::: :. : ::.:: XP_016 MSLMVVSMACVGFFLLQGAWTHEGGQDKPLLSAWPSTVVPRGGHVTLLCRSRLGFTIF 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 TLYKKDGVPVPELYNRIFWNSFLISPVTPAHAGTYRCRGFHPHSPTEWSAPSNPLVIMVT .:::.::::::::::.:::.:.:..:::::::::::::: ::.:: :::::::::::.:: XP_016 SLYKEDGVPVPELYNKIFWKSILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVIVVT 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 GLYEKPSLTARPGPTVRTGENVTLSCSSQSSFDIYHLSREGEAHELRLPAVPSINGTFQA ::. ::::.:.:::::::::::::::::.::::.:::::::.::: :::::::.:::::: XP_016 GLFGKPSLSAQPGPTVRTGENVTLSCSSRSSFDMYHLSREGRAHEPRLPAVPSVNGTFQA 120 130 140 150 160 170 190 200 210 220 230 pF1KB6 DFPLGPATHGETYRCFGSFHGSPYEWSDASDPLPVSVTGNPSSSWPSPTEPSFKT----- :::::::::: :: ::::.: ::::::: :::: :::::: ::: :::::: :: XP_016 DFPLGPATHGGTYTCFGSLHDSPYEWSDPSDPLLVSVTGNSSSSSSSPTEPSSKTGIRRH 180 190 200 210 220 230 240 250 260 pF1KB6 ------------------------------DAAVMNQEPAGHRTVNREDSDEQDPQEVTY .::::.::::: :::::::::.:::::::: XP_016 LHILIGTSVAIILFIILFFFLLHCCCSNKKNAAVMDQEPAGDRTVNREDSDDQDPQEVTY 240 250 260 270 280 290 270 280 290 300 310 320 pF1KB6 AQLDHCIFTQRKITGPSQRSKRPSTDTSVCIELPNAEPRALSPAHEHHSQALMGSSRETT ::::::.::: :::.:::: : : :::.. .:::::.::.:::::.:::::: ::::::: XP_016 AQLDHCVFTQTKITSPSQRPKTPPTDTTMYMELPNAKPRSLSPAHKHHSQALRGSSRETT 300 310 320 330 340 350 330 340 pF1KB6 ALSQTQLASSNVPAAGI ::::...:::.::: XP_016 ALSQNRVASSHVPAAGI 360 370 >>XP_016885761 (OMIM: 615727) PREDICTED: killer cell imm (375 aa) initn: 1284 init1: 1284 opt: 1284 Z-score: 1114.5 bits: 214.8 E(85289): 2.4e-55 Smith-Waterman score: 1759; 71.0% identity (82.8% similar) in 372 aa overlap (3-339:1-372) 10 20 30 40 50 60 pF1KB6 MSMSPTVIILACLGFFLDQSVWAHVGGQDKPFCSAWPSAVVPQGGHVTLRCHYRRGFNIF :: :. .::.:::: :..:.: ::::::. :::::::::.:::::: :. : ::.:: XP_016 MSLMVVSMACVGFFLLQGAWTHEGGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIF 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 TLYKKDGVPVPELYNRIFWNSFLISPVTPAHAGTYRCRGFHPHSPTEWSAPSNPLVIMVT .:::.::::::::::.:::.:.:..:::::::::::::: ::.:: :::::::::::.:: XP_016 SLYKEDGVPVPELYNKIFWKSILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVIVVT 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 GLYEKPSLTARPGPTVRTGENVTLSCSSQSSFDIYHLSREGEAHELRLPAVPSINGTFQA ::. ::::.:.:::::::::::::::::.::::.:::::::.::: :::::::..::::: XP_016 GLFGKPSLSAQPGPTVRTGENVTLSCSSRSSFDMYHLSREGRAHEPRLPAVPSVDGTFQA 120 130 140 150 160 170 190 200 210 220 230 pF1KB6 DFPLGPATHGETYRCFGSFHGSPYEWSDASDPLPVSVTGNPSSSWPSPTEPSFKT----- :::::::::: :: ::.:.: ::::::: :::: :::::: ::: :::::: :: XP_016 DFPLGPATHGGTYTCFSSLHDSPYEWSDPSDPLLVSVTGNSSSSSSSPTEPSSKTGIRRH 180 190 200 210 220 230 240 250 260 pF1KB6 ------------------------------DAAVMNQEPAGHRTVNREDSDEQDPQEVTY .::::.::::: :::::::::.:::::::: XP_016 LHILIGTSVAIILFIILFFFLLHCCCSNKKNAAVMDQEPAGDRTVNREDSDDQDPQEVTY 240 250 260 270 280 290 270 280 290 300 310 320 pF1KB6 AQLDHCIFTQRKITGPSQRSKRPSTDTSVCIELPNAEPRALSPAHEHHSQALMGSSRETT ::::::.::: :::.:::: : : :::.. .:::::.::.:::::.:::::: ::::::: XP_016 AQLDHCVFTQTKITSPSQRPKTPPTDTTMYMELPNAKPRSLSPAHKHHSQALRGSSRETT 300 310 320 330 340 350 330 340 pF1KB6 ALSQTQLASSNVPAAGI ::::...:::.::: XP_016 ALSQNRVASSHVPAAGI 360 370 >>XP_016885731 (OMIM: 615727) PREDICTED: killer cell imm (375 aa) initn: 1284 init1: 1284 opt: 1284 Z-score: 1114.5 bits: 214.8 E(85289): 2.4e-55 Smith-Waterman score: 1759; 71.0% identity (82.8% similar) in 372 aa overlap (3-339:1-372) 10 20 30 40 50 60 pF1KB6 MSMSPTVIILACLGFFLDQSVWAHVGGQDKPFCSAWPSAVVPQGGHVTLRCHYRRGFNIF :: :. .::.:::: :..:.: ::::::. :::::::::.:::::: :. : ::.:: XP_016 MSLMVVSMACVGFFLLQGAWTHEGGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIF 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 TLYKKDGVPVPELYNRIFWNSFLISPVTPAHAGTYRCRGFHPHSPTEWSAPSNPLVIMVT .:::.::::::::::.:::.:.:..:::::::::::::: ::.:: :::::::::::.:: XP_016 SLYKEDGVPVPELYNKIFWKSILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVIVVT 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 GLYEKPSLTARPGPTVRTGENVTLSCSSQSSFDIYHLSREGEAHELRLPAVPSINGTFQA ::. ::::.:.:::::::::::::::::.::::.:::::::.::: :::::::..::::: XP_016 GLFGKPSLSAQPGPTVRTGENVTLSCSSRSSFDMYHLSREGRAHEPRLPAVPSVDGTFQA 120 130 140 150 160 170 190 200 210 220 230 pF1KB6 DFPLGPATHGETYRCFGSFHGSPYEWSDASDPLPVSVTGNPSSSWPSPTEPSFKT----- :::::::::: :: ::.:.: ::::::: :::: :::::: ::: :::::: :: XP_016 DFPLGPATHGGTYTCFSSLHDSPYEWSDPSDPLLVSVTGNSSSSSSSPTEPSSKTGIRRH 180 190 200 210 220 230 240 250 260 pF1KB6 ------------------------------DAAVMNQEPAGHRTVNREDSDEQDPQEVTY .::::.::::: :::::::::.:::::::: XP_016 LHILIGTSVAIILFIILFFFLLHCCCSNKKNAAVMDQEPAGDRTVNREDSDDQDPQEVTY 240 250 260 270 280 290 270 280 290 300 310 320 pF1KB6 AQLDHCIFTQRKITGPSQRSKRPSTDTSVCIELPNAEPRALSPAHEHHSQALMGSSRETT ::::::.::: :::.:::: : : :::.. .:::::.::.:::::.:::::: ::::::: XP_016 AQLDHCVFTQTKITSPSQRPKTPPTDTTMYMELPNAKPRSLSPAHKHHSQALRGSSRETT 300 310 320 330 340 350 330 340 pF1KB6 ALSQTQLASSNVPAAGI ::::...:::.::: XP_016 ALSQNRVASSHVPAAGI 360 370 >>NP_001018091 (OMIM: 615727) killer cell immunoglobulin (375 aa) initn: 1280 init1: 1280 opt: 1280 Z-score: 1111.1 bits: 214.1 E(85289): 3.8e-55 Smith-Waterman score: 1745; 70.7% identity (82.5% similar) in 372 aa overlap (3-339:1-372) 10 20 30 40 50 60 pF1KB6 MSMSPTVIILACLGFFLDQSVWAHVGGQDKPFCSAWPSAVVPQGGHVTLRCHYRRGFNIF :: :: .::.:::: :..:.: ::::::. :::::::::.:::::: :. : ::.:: NP_001 MSLMVISMACVGFFLLQGAWTHEGGQDKPLLSAWPSAVVPRGGHVTLLCRSRLGFTIF 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 TLYKKDGVPVPELYNRIFWNSFLISPVTPAHAGTYRCRGFHPHSPTEWSAPSNPLVIMVT .:::.::::::::::.:::.:.:..:::::::::::::: ::.:: :::::::::::.:: NP_001 SLYKEDGVPVPELYNKIFWKSILMGPVTPAHAGTYRCRGSHPRSPIEWSAPSNPLVIVVT 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 GLYEKPSLTARPGPTVRTGENVTLSCSSQSSFDIYHLSREGEAHELRLPAVPSINGTFQA ::. ::::.:.:::::::::::.:::::.::::.:::::::.::: :::::::..::::: NP_001 GLFGKPSLSAQPGPTVRTGENVALSCSSRSSFDMYHLSREGRAHEPRLPAVPSVDGTFQA 120 130 140 150 160 170 190 200 210 220 230 pF1KB6 DFPLGPATHGETYRCFGSFHGSPYEWSDASDPLPVSVTGNPSSSWPSPTEPSFKT----- :::::::::: :: ::.:.: ::::::: :::: :::::: ::: :::::: :: NP_001 DFPLGPATHGGTYTCFSSLHDSPYEWSDPSDPLLVSVTGNSSSSSSSPTEPSSKTGIRRH 180 190 200 210 220 230 240 250 260 pF1KB6 ------------------------------DAAVMNQEPAGHRTVNREDSDEQDPQEVTY .::::.: ::: :::::::::.:::::::: NP_001 LHILIGTSVAIILFIILFFFLLHCCCSNKKNAAVMDQGPAGDRTVNREDSDDQDPQEVTY 240 250 260 270 280 290 270 280 290 300 310 320 pF1KB6 AQLDHCIFTQRKITGPSQRSKRPSTDTSVCIELPNAEPRALSPAHEHHSQALMGSSRETT ::::::.::: :::.:::: : : :::.. .:::::.::.:::::.:::::: ::::::: NP_001 AQLDHCVFTQTKITSPSQRPKAPPTDTTMYMELPNAKPRSLSPAHKHHSQALRGSSRETT 300 310 320 330 340 350 330 340 pF1KB6 ALSQTQLASSNVPAAGI ::::...:::.::: NP_001 ALSQNRVASSHVPAAGI 360 370 >>XP_016885768 (OMIM: 615727) PREDICTED: killer cell imm (386 aa) initn: 1262 init1: 1262 opt: 1262 Z-score: 1095.5 bits: 211.3 E(85289): 2.8e-54 Smith-Waterman score: 1737; 72.3% identity (83.1% similar) in 361 aa overlap (14-339:23-383) 10 20 30 40 50 pF1KB6 MSMSPTVIILACLGFFLDQSVWAHVGGQDKPFCSAWPSAVVPQGGHVTLRC :::: :..:.: ::::::. :::::::::.:::::: : XP_016 MGLQAGSLHSRQPCSWVQAGTEGFFLLQGAWTHEGGQDKPLLSAWPSAVVPRGGHVTLLC 10 20 30 40 50 60 60 70 80 90 100 110 pF1KB6 HYRRGFNIFTLYKKDGVPVPELYNRIFWNSFLISPVTPAHAGTYRCRGFHPHSPTEWSAP . : ::.::.:::.::::::::::.:::.:.:..:::::::::::::: ::.:: ::::: XP_016 RSRLGFTIFSLYKEDGVPVPELYNKIFWKSILMGPVTPAHAGTYRCRGSHPRSPIEWSAP 70 80 90 100 110 120 120 130 140 150 160 170 pF1KB6 SNPLVIMVTGLYEKPSLTARPGPTVRTGENVTLSCSSQSSFDIYHLSREGEAHELRLPAV ::::::.::::. ::::.:.:::::::::::::::::.::::.:::::::.::: ::::: XP_016 SNPLVIVVTGLFGKPSLSAQPGPTVRTGENVTLSCSSRSSFDMYHLSREGRAHEPRLPAV 130 140 150 160 170 180 180 190 200 210 220 230 pF1KB6 PSINGTFQADFPLGPATHGETYRCFGSFHGSPYEWSDASDPLPVSVTGNPSSSWPSPTEP ::.:::::::::::::::: :: ::::.: ::::::: :::: :::::: ::: ::::: XP_016 PSVNGTFQADFPLGPATHGGTYTCFGSLHDSPYEWSDPSDPLLVSVTGNSSSSSSSPTEP 190 200 210 220 230 240 240 250 pF1KB6 SFKT-----------------------------------DAAVMNQEPAGHRTVNREDSD : :: .::::.::::: ::::::::: XP_016 SSKTGIRRHLHILIGTSVAIILFIILFFFLLHCCCSNKKNAAVMDQEPAGDRTVNREDSD 250 260 270 280 290 300 260 270 280 290 300 310 pF1KB6 EQDPQEVTYAQLDHCIFTQRKITGPSQRSKRPSTDTSVCIELPNAEPRALSPAHEHHSQA .::::::::::::::.::: :::.:::: : : :::.. .:::::.::.:::::.::::: XP_016 DQDPQEVTYAQLDHCVFTQTKITSPSQRPKTPPTDTTMYMELPNAKPRSLSPAHKHHSQA 310 320 330 340 350 360 320 330 340 pF1KB6 LMGSSRETTALSQTQLASSNVPAAGI : :::::::::::...:::.::: XP_016 LRGSSRETTALSQNRVASSHVPAAGI 370 380 >>XP_011525242 (OMIM: 604947) PREDICTED: killer cell imm (420 aa) initn: 1977 init1: 1159 opt: 1232 Z-score: 1069.2 bits: 206.6 E(85289): 8.1e-53 Smith-Waterman score: 1232; 65.7% identity (80.4% similar) in 286 aa overlap (26-305:119-403) 10 20 30 40 50 pF1KB6 MSMSPTVIILACLGFFLDQSVWAHVGGQDKPFCSAWPSAVVPQGGHVTLRCHYRR :.. :: : :. .. .: : :.: XP_011 HAGTYRCRGSRPHSLTGWSAPSNPLVIMVTGNHRKPSLLAHPGPLLKSGETVILQCWSDV 90 100 110 120 130 140 60 70 80 90 100 pF1KB6 GFNIFTLYKKDGV---P---VPELYNRIFWNSFLISPVTPAHAGTYRCRGFHPHSPTEWS :. : :.. .:. : : .... . .: :.:. :. :::::: : :::: . : XP_011 MFEHFFLHR-EGISEDPSRLVGQIHDGVSKANFSIGPLMPVLAGTYRCYGSVPHSPYQLS 150 160 170 180 190 200 110 120 130 140 150 160 pF1KB6 APSNPLVIMVTGLYEKPSLTARPGPTVRTGENVTLSCSSQSSFDIYHLSREGEAHELRLP :::.:: :..:::::::::.:.:::::..:::::::::: ::.::::::::::::: :: XP_011 APSDPLDIVITGLYEKPSLSAQPGPTVQAGENVTLSCSSWSSYDIYHLSREGEAHERRLR 210 220 230 240 250 260 170 180 190 200 210 220 pF1KB6 AVPSINGTFQADFPLGPATHGETYRCFGSFHGSPYEWSDASDPLPVSVTGNPSSSWPSPT :::..: :::::::::::::: ::::::::.. : ::..:::: ::::::::::::::: XP_011 AVPKVNRTFQADFPLGPATHGGTYRCFGSFRALPCVWSNSSDPLLVSVTGNPSSSWPSPT 270 280 290 300 310 320 230 240 250 260 270 280 pF1KB6 EPSFKTDAAVMNQEPAGHRTVNREDSDEQDPQEVTYAQLDHCIFTQRKITGPSQRSKRPS ::: :.:::::.::::: :::::.::::::::::::::::::.: ::::. :::: : : XP_011 EPSSKSDAAVMDQEPAGDRTVNRQDSDEQDPQEVTYAQLDHCVFIQRKISRPSQRPKTPL 330 340 350 360 370 380 290 300 310 320 330 340 pF1KB6 TDTSVCIELPNAEPRALSPAHEHHSQALMGSSRETTALSQTQLASSNVPAAGI ::::: ::::::::. XP_011 TDTSVYTELPNAEPRSKVVSCPRAPQSGLEGVF 390 400 410 420 >-- initn: 576 init1: 576 opt: 576 Z-score: 507.0 bits: 102.5 E(85289): 1.7e-21 Smith-Waterman score: 576; 69.5% identity (85.6% similar) in 118 aa overlap (3-120:1-118) 10 20 30 40 50 60 pF1KB6 MSMSPTVIILACLGFFLDQSVWAHVGGQDKPFCSAWPSAVVPQGGHVTLRCHYRRGFNIF :: ::. .::.:::: :..: .::::::: :: ::.:::.::::.:.:::::::: : XP_011 MSLTVVSMACVGFFLLQGAWPLMGGQDKPFLSARPSTVVPRGGHVALQCHYRRGFNNF 10 20 30 40 50 70 80 90 100 110 120 pF1KB6 TLYKKDGVPVPELYNRIFWNSFLISPVTPAHAGTYRCRGFHPHSPTEWSAPSNPLVIMVT :::.: :: ...::: .::...:::::::::::::: .::: : ::::::::::::: XP_011 MLYKEDRSHVPIFHGRIFQESFIMGPVTPAHAGTYRCRGSRPHSLTGWSAPSNPLVIMVT 60 70 80 90 100 110 130 140 150 160 170 180 pF1KB6 GLYEKPSLTARPGPTVRTGENVTLSCSSQSSFDIYHLSREGEAHELRLPAVPSINGTFQA XP_011 GNHRKPSLLAHPGPLLKSGETVILQCWSDVMFEHFFLHREGISEDPSRLVGQIHDGVSKA 120 130 140 150 160 170 342 residues in 1 query sequences 60827320 residues in 85289 library sequences Tcomplib [36.3.4 Apr, 2011] (8 proc) start: Sat Nov 5 08:48:39 2016 done: Sat Nov 5 08:48:41 2016 Total Scan time: 8.780 Total Display time: 0.030 Function used was FASTA [36.3.4 Apr, 2011]